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John Gearhart

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Nikta Pashai; ANGELO ALL; Raghothama Chaerkady; Alejandro De Los Angeles; John D Gearhart; Siddharth Gupta; Haiping Hao; Candace Kerr
Genome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells.
Raghothama Chaerkady; Bernard Delanghe; John D Gearhart; Praveen Kumar; Brian Letzen; Akhilesh Pandey; Santosh Renuse; Nandini A Sahasrabuddhe; Nitish V Thakor; ANGELO ALL; Candace Kerr
Quantitative temporal proteomic analysis of human embryonic stem cell differentiation into oligodendrocyte progenitor cells.
P Esteso; John D Gearhart
The use of human embryonic stem cells in drug discovery. Counterpoint.

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All Publications

2012: Nikta Pashai; ANGELO ALL; Raghothama Chaerkady; Alejandro De Los Angeles; John D Gearhart; Siddharth Gupta; Haiping Hao; Candace Kerr
Genome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells.
PloS one 2012;7(6):e39088.
2011: Raghothama Chaerkady; Bernard Delanghe; John D Gearhart; Praveen Kumar; Brian Letzen; Akhilesh Pandey; Santosh Renuse; Nandini A Sahasrabuddhe; Nitish V Thakor; ANGELO ALL; Candace Kerr
Quantitative temporal proteomic analysis of human embryonic stem cell differentiation into oligodendrocyte progenitor cells.
Proteomics 2011;11(20):4007-20.
2011: P Esteso; John D Gearhart
The use of human embryonic stem cells in drug discovery. Counterpoint.
Clinical pharmacology and therapeutics 2011;89(5):641-3.
2011: Marc Hiller; Cyndi Liu; Paul D Blumenthal; John D Gearhart; Candace Kerr
Bone morphogenetic protein 4 mediates human embryonic germ cell derivation.
Stem cells and development 2011;20(2):351-61.
2011: John D Gearhart; Christos Coutifaris
In vitro fertilization, the Nobel Prize, and human embryonic stem cells.
Cell stem cell 2011;8(1):12-5.
2011: Russell C Addis; Rebecca L Wright; Douglas A Coulter; Fu-Chun Hsu; Marc A Dichter; John D Gearhart
Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector.
PloS one 2011;6(12):e28719.
2011: Samantha Maragh; Aida M Bertoli Avella; Seneca L Bessling; Bianca de Graaf; Shannon Fisher; John D Gearhart; David M McGaughey; Ronald A Miller; Eric A Stone; Marja W Wessels; Andy McCallion
Identification of RNA binding motif proteins essential for cardiovascular development.
BMC developmental biology 2011;11():62.
2010: Candace Kerr; Brian S Letzen; Christine M Hill; Gracee Agrawal; Nitish V Thakor; Jared L Sterneckert; John D Gearhart; ANGELO ALL
Efficient differentiation of human embryonic stem cells into oligodendrocyte progenitors for application in a rat contusion model of spinal cord injury.
The International journal of neuroscience 2010;120(4):305-13.
2010: Raghothama Chaerkady; Candace Kerr; Richard Kumaran Kandasamy; Arivusudar Marimuthu; John D Gearhart; Akhilesh Pandey
Comparative proteomics of human embryonic stem cells and embryonal carcinoma cells.
Proteomics 2010;10(7):1359-73.
2010: Nicolas Christoforou; Behzad Nasehi Oskouei; Paul Esteso; Christine M Hill; Jeffrey M Zimmet; Weining Bian; Nenad Bursac; Kam W Leong; Joshua M Hare; John D Gearhart
Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts.
PloS one 2010;5(7):e11536.
2010: Brian S Letzen; Cyndi Liu; Nitish V Thakor; John D Gearhart; ANGELO ALL; Candace Kerr
MicroRNA expression profiling of oligodendrocyte differentiation from human embryonic stem cells.
PloS one 2010;5(5):e10480.
2009: P S Duggan; Andrew Siegel; David M Blass; H Bok; J T Coyle; Ruth R Faden; J Finkel; John D Gearhart; H T Greely; ARGYE HILLIS-TRUPE; Ahmet Hoke; Richard T Johnson; Michael V Johnston; J Kahn; Douglas A Kerr; P King; J Kurtzberg; S M Liao; JOHN MCDONALD; Guy M McKhann; K B Nelson; Mahendra S Rao; A Regenberg; Kirby D Smith; D Solter; Hongjun Song; Jeremy Sugarman; R J Traystman; A Vescovi; J Yanofski; W Young; Debra J H Mathews
Unintended changes in cognition, mood, and behavior arising from cell-based interventions for neurological conditions: ethical challenges.
The American journal of bioethics : AJOB 2009;9(5):31-6.
2009: Raghothama Chaerkady; Candace Kerr; Arivusudar Marimuthu; Dhanashree S Kelkar; Manoj Kumar Kashyap; Marjan Gucek; John D Gearhart; Akhilesh Pandey
Temporal analysis of neural differentiation using quantitative proteomics.
Journal of proteome research 2009;8(3):1315-26.
2009: John D Gearhart; Russell C Addis
The use of animals in human stem cell research: past, present, and future.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2009;51(1):1-2.
2009: John D Gearhart
A decade of stem-cell research. An interview with John Gearhart, Director of the Institute for Regenerative Medicine at the University of Pennsylvania, USA. Interview by Howard Wolinsky.
EMBO reports 2009;10(1):12-6.
2009: Alan Regenberg; Debra J H Mathews; David M Blass; Hilary Bok; Joseph T Coyle; Patrick Duggan; Ruth R Faden; Julia Finkel; John D Gearhart; ARGYE HILLIS-TRUPE; Ahmet Hoke; Richard T Johnson; Michael V Johnston; Jeffrey Kahn; Douglas A Kerr; Patricia King; Joanne Kurtzberg; S Matthew Liao; JOHN MCDONALD; Guy M McKhann; Karin B Nelson; Mahendra S Rao; Andrew Siegel; Kirby D Smith; Davor Solter; Hongjun Song; Jeremy Sugarman; Angelo Vescovi; Wise Young; Henry T Greely; Richard J Traystman
The role of animal models in evaluating reasonable safety and efficacy for human trials of cell-based interventions for neurologic conditions.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2009;29(1):1-9.
2008: Ethan S Patterson; Russell C Addis; Michael J Shamblott; John D Gearhart
SOX17 directly activates Zfp202 transcription during in vitro endoderm differentiation.
Physiological genomics 2008;34(3):277-84.
2008: Jacobus F A Jansen; John D Gearhart; Jeff W M Bulte
Comment on "Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain".
Science (New York, N.Y.) 2008;321(5889):640;author reply 640.
2008: Debra J H Mathews; Jeremy Sugarman; Hilary Bok; David M Blass; J T Coyle; P Duggan; J Finkel; H T Greely; ARGYE HILLIS-TRUPE; Ahmet Hoke; Richard T Johnson; Michael V Johnston; J Kahn; Douglas A Kerr; J Kurtzberg; S Matthew Liao; JOHN MCDONALD; Guy M McKhann; K B Nelson; Mahendra S Rao; A Regenberg; Andrew Siegel; Kirby D Smith; Davor Solter; Hongjun Song; A Vescovi; W Young; John D Gearhart; Ruth R Faden
Cell-based interventions for neurologic conditions: ethical challenges for early human trials.
Neurology 2008;71(4):288-93.
2008: R C Addis; Jeff W M Bulte; John D Gearhart
Special cells, special considerations: the challenges of bringing embryonic stem cells from the laboratory to the clinic.
Clinical pharmacology and therapeutics 2008;83(3):386-9.
2008: Nicolas Christoforou; Ronald A Miller; Christine M Hill; Chunfa Jie; Andy McCallion; John D Gearhart
Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes.
The Journal of clinical investigation 2008;118(3):894-903.
2008: Candace Kerr; Christine M Hill; Paul D Blumenthal; John D Gearhart
Expression of pluripotent stem cell markers in the human fetal ovary.
Human reproduction (Oxford, England) 2008;23(3):589-99.
2008: Candace Kerr; Christine M Hill; Paul D Blumenthal; John D Gearhart
Expression of pluripotent stem cell markers in the human fetal testis.
Stem cells (Dayton, Ohio) 2008;26(2):412-21.
2008: Bibhuti Mishra; John D Gearhart; Vassilios Papadopoulos
Disease markers. Foreword.
Disease markers 2008;24(4-5):199-200.
2008: Ronald A Miller; Nicolas Christoforou; Jonathan Pevsner; Andy McCallion; John D Gearhart
Efficient array-based identification of novel cardiac genes through differentiation of mouse ESCs.
PloS one 2008;3(5):e2176.
2007: John D Gearhart; Evanthia E Pashos; Megana K Prasad
Pluripotency redux--advances in stem-cell research.
The New England journal of medicine 2007;357(15):1469-72.
2007: Nicolas Christoforou; John D Gearhart
Stem cells and their potential in cell-based cardiac therapies.
Progress in cardiovascular diseases 2007;49(6):396-413.
2006: Candace Kerr; John D Gearhart; Aaron M Elliott; Peter J Donovan
Embryonic germ cells: when germ cells become stem cells.
Seminars in reproductive medicine 2006;24(5):304-13.
2006: Jacobus F A Jansen; Michael J Shamblott; Peter C M van Zijl; Kimmo Kristian Lehtimäki; Jeff W M Bulte; John D Gearhart; Juhana M Hakumäki
Stem cell profiling by nuclear magnetic resonance spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(3):666-70.
2006: Dominic Frimberger; Nelly Morales; John D Gearhart; John P Gearhart; Yegappan Lakshmanan
Human embryoid body-derived stem cells in tissue engineering-enhanced migration in co-culture with bladder smooth muscle and urothelium.
Urology 2006;67(6):1298-303.
2006: Candace Kerr; Michael J Shamblott; John D Gearhart
Pluripotent stem cells from germ cells.
Methods in enzymology 2006;419():400-26.
2005: Ian Wilmut; Michael D West; Robert Lanza; John D Gearhart; Austin Smith; Alan Colman; Alan O Trounson; Keith Campbell
Human embryonic stem cells.
Science (New York, N.Y.) 2005;310(5756):1903.
2005: Dawn Mueller; Michael J Shamblott; Harold E Fox; John D Gearhart; Lee J Martin
Transplanted human embryonic germ cell-derived neural stem cells replace neurons and oligodendrocytes in the forebrain of neonatal mice with excitotoxic brain damage.
Journal of neuroscience research 2005;82(5):592-608.
2005: Mark Greene; Kathryn Schill; Shoji Takahashi; Alison Bateman-House; Tom L Beauchamp; Hilary Bok; Dorothy Cheney; Joseph Coyle; Terrence Deacon; Daniel Dennett; Peter Donovan; Owen Flanagan; Steven Goldman; Henry T Greely; Lee J Martin; Earl Miller; Dawn Mueller; Andrew Siegel; Davor Solter; John D Gearhart; Guy M McKhann; Ruth R Faden
Ethics: Moral issues of human-non-human primate neural grafting.
Science (New York, N.Y.) 2005;309(5733):385-6.
2005: Dominic Frimberger; Nelly Morales; Michael J Shamblott; John D Gearhart; John P Gearhart; Yegappan Lakshmanan
Human embryoid body-derived stem cells in bladder regeneration using rodent model.
Urology 2005;65(4):827-32.
2005: Yegappan Lakshmanan; Dominic Frimberger; John D Gearhart; John P Gearhart
Human embryoid body-derived stem cells in co-culture with bladder smooth muscle and urothelium.
Urology 2005;65(4):821-6.
2005: Jared L Sterneckert; Christine M Hill; Richard Palmer; John D Gearhart
Bone morphogenetic proteins produced by cells within embryoid bodies inhibit ventral directed differentiation by Sonic Hedgehog.
Cloning and stem cells 2005;7(1):27-34.
2005: Myoung Sook Kim; Nathaniel Hwang; Janice Lee; Tae-Kyun Kim; Kam Leong; Michael J Shamblott; John D Gearhart; Jennifer H Elisseeff
Musculoskeletal differentiation of cells derived from human embryonic germ cells.
Stem cells (Dayton, Ohio) 2005;23(1):113-23.
2004: Ruth R Faden; John D Gearhart
Facts on stem cells.
Washington post (Washington, D.C. : 1974) 2004;():A15.
2004: Xiangcan Zhan; Gautam Dravid; Zhaohui Ye; Holly Hammond; Michael J Shamblott; John D Gearhart; Linzhao Cheng
Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro.
Lancet 2004;364(9429):163-71.
2004: John D Gearhart
New human embryonic stem-cell lines--more is better.
The New England journal of medicine 2004;350(13):1275-6.
2003: Ruth R Faden; Liza Dawson; Alison S Bateman-House; Dawn Mueller Agnew; Hilary Bok; Dan W Brock; Aravinda Chakravarti; Xiao-Jiang Gao; Mark Greene; John A Hansen; Patricia A King; Stephen J O'Brien; David H Sachs; Kathryn E Schill; Andrew Siegel; Davor Solter; Sonia M Suter; Catherine M Verfaillie; LeRoy B Walters; John D Gearhart
Public stem cell banks: considerations of justice in stem cell research and therapy.
The Hastings Center report 2003;33(6):13-27.
2003: M A Siddiqi; G M Kilduff; John D Gearhart
Use of a night vision intensifier for direct visualization by eye of far-red and near-infrared fluorescence through an optical microscope.
Journal of microscopy 2003;212(Pt 2):132-43.
2003: Liza Dawson; Alison S Bateman-House; Dawn Mueller Agnew; Hilary Bok; Dan W Brock; Aravinda Chakravarti; Mark Greene; Patricia A King; Stephen J O'Brien; David H Sachs; Kathryn E Schill; Andrew Siegel; Davor Solter; Sonia M Suter; Catherine M Verfaillie; LeRoy B Walters; John D Gearhart; Ruth R Faden
Safety issues in cell-based intervention trials.
Fertility and sterility 2003;80(5):1077-85.
2003: Douglas A Kerr; Jerònia Lladó; Michael J Shamblott; Nicholas J Maragakis; David N Irani; Thomas O Crawford; Chitra Krishnan; Sonny Dike; John D Gearhart; Jeffrey rothstein
Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(12):5131-40.
2002: Timothy H Moran; George T Capone; Susan Knipp; Muriel T Davisson; Roger H Reeves; John D Gearhart
The effects of piracetam on cognitive performance in a mouse model of Down's syndrome.
Physiology & behavior 2002;77(2-3):403-9.
2002: Ie-Ming Shih; Mei-Yu Hsu; Robert J Oldt; Meenhard Herlyn; John D Gearhart; Robert J Kurman
The Role of E-cadherin in the Motility and Invasion of Implantation Site Intermediate Trophoblast.
Placenta 2002;23(10):706-15.
2002: Patrick Onyango; Shan Jiang; Hiroshi Uejima; Michael J Shamblott; John D Gearhart; Hengmi Cui; Andrew P Feinberg
Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10599-604.
2002: Michael J Shamblott; Elizabeth M Bugg; Ann M Lawler; John D Gearhart
Craniofacial abnormalities resulting from targeted disruption of the murine Sim2 gene.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;224(4):373-80.
2002: Timothy N Hickman; Le-Ming Shih; Howard Zacur; Robert J Kurman; Marie Diener-West; John D Gearhart
Decreased progesterone receptor expression in the intermediate trophoblastic cells of spontaneous abortions.
Fertility and sterility 2002;77(5):1001-5.
2001: P J Donovan; John D Gearhart
The end of the beginning for pluripotent stem cells.
Nature 2001;414(6859):92-7.
2001: Nikos F. Vlahos; Elizabeth M Bugg; Michael J Shamblott; John Y Phelps; John D Gearhart; Howard Zacur
Prolactin receptor gene expression and immunolocalization of the prolactin receptor in human luteinized granulosa cells.
Molecular human reproduction 2001;7(11):1033-8.
2001: Michael J Shamblott; Joyce Axelman; J W Littlefield; P D Blumenthal; George Huggins; Y Cui; Linzhao Cheng; John D Gearhart
Human embryonic germ cell derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(1):113-8.
2000: LM Call; CS Moore; Gail Stetten; John D Gearhart
A cre-lox recombination system for the targeted integration of circular yeast artificial chromosomes into embryonic stem cells.
Human molecular genetics 2000;9(12):1745-51.
2000: B E Edwards; John D Gearhart; Edward E Wallach
The human pluripotent stem cell: impact on medicine and society.
Fertility and sterility 2000;74(1):1-7.
1999: Davor Solter; John D Gearhart
Putting stem cells to work.
Science (New York, N.Y.) 1999;283(5407):1468-70.
1999: Ying Litingtung; Ann M Lawler; Suzanne M Sebald; E Lee; John D Gearhart; Heiner Westphal; Jeffry L Corden
Growth retardation and neonatal lethality in mice with a homozygous deletion in the C-terminal domain of RNA polymerase II.
Molecular & general genetics : MGG 1999;261(1):100-5.
1998: Michael J Shamblott; Joyce Axelman; S Wang; Elizabeth M Bugg; J W Littlefield; P J Donovan; P D Blumenthal; George Huggins; John D Gearhart
Derivation of pluripotent stem cells from cultured human primordial germ cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13726-31.
1998: John D Gearhart
New potential for human embryonic stem cells.
Science (New York, N.Y.) 1998;282(5391):1061-2.
1998: Ann M Lawler; John D Gearhart
Genetic counseling for patients who will be undergoing treatment with assisted reproductive technology.
Fertility and sterility 1998;70(3):412-3.
1998: Ie-Ming Shih; Tian-Li Wang; Tzyy-choou Wu; Robert J Kurman; John D Gearhart
Expression of Mel-CAM in implantation site intermediate trophoblastic cell line, IST-1, limits its migration on uterine smooth muscle cells.
Journal of cell science 1998;111 ( Pt 17)():2655-64.
1998: CS Moore; Corey H Mjaatvedt; John D Gearhart
Expression and function of activin beta A during mouse cardiac cushion tissue formation.
Developmental dynamics : an official publication of the American Association of Anatomists 1998;212(4):548-62.
1998: Lopa Mishra; T Cai; A Levine; D Weng; E Mezey; B Mishra; John D Gearhart
Identification of elf1, a beta-spectrin, in early mouse liver development.
The International journal of developmental biology 1998;42(2):221-4.
1998: Narayan Iyer; Lori E Kotch; Faton H Agani; Steve W Leung; E Laughner; R H Wenger; M Gassmann; John D Gearhart; Ann M Lawler; AY Yu; Gregg L Semenza
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha.
Genes & development 1998;12(2):149-62.
1997: Ie-Ming Shih; Ronald Schnaar; John D Gearhart; Robert J Kurman
Distribution of cells bearing the HNK-1 epitope in the human placenta.
Placenta 1997;18(8):667-74.
1997: William Schwindinger; Kimberly J Reese; Ann M Lawler; John D Gearhart; Michael Levine
Targeted disruption of Gnas in embryonic stem cells.
Endocrinology 1997;138(10):4058-63.
1997: Bruce Lamb; LM Call; Hilda H Slunt; K A Bardel; Ann M Lawler; Christopher B Eckman; Steven G Younkin; Greg Holtz; Steven L Wagner; Donald L Price; Sangram S Sisodia; John D Gearhart
Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.
Human molecular genetics 1997;6(9):1535-41.
1997: C Montrose-Rafizadeh; Jolanta Kole; L M Bartkowski; L H Lee; D L Blackmon; S E Behnken; John D Gearhart; Jonathan A Cohn; MH Montrose
Gene targeting of a CFTR allele in HT29 human epithelial cells.
Journal of cellular physiology 1997;170(3):299-308.
1996: Noel Y Calingasan; Sam Gandy; H Baker; KF Sheu; Jonathan D. Smith; Bruce Lamb; John D Gearhart; Joseph Buxbaum; C Harper; Dennis J Selkoe; Donald L Price; Sangram S Sisodia; Gary Gibson
Novel neuritic clusters with accumulations of amyloid precursor protein and amyloid precursor-like protein 2 immunoreactivity in brain regions damaged by thiamine deficiency.
The American journal of pathology 1996;149(3):1063-71.
1996: C Rosenberg; A K Voltz; Ann M Lawler; Bruce Lamb; Gail Stetten; John D Gearhart
Alterations of yeast artificial chromosome transgenic sequences in stretched embryonic stem-cell chromatin visualized by fluorescence in situ hybridization.
Cytogenetics and cell genetics 1996;75(1):67-70.
1995: Michael Bustin; P J Alfonso; J M Pash; J M Ward; John D Gearhart; Roger H Reeves
Characterization of transgenic mice with an increased content of chromosomal protein HMG-14 in their chromatin.
DNA and cell biology 1995;14(12):997-1005.
1995: Bruce Lamb; John D Gearhart
YAC transgenics and the study of genetics and human disease.
Current opinion in genetics & development 1995;5(3):342-8.
1995: L Bi; Ann M Lawler; Stylianos Antonarakis; K A High; John D Gearhart; Haig Kazazian
Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A.
Nature genetics 1995;10(1):119-21.
1994: Roger H Reeves; J Yao; M R Crowley; S Buck; X Zhang; Paul J Yarowsky; John D Gearhart; D C Hilt
Astrocytosis and axonal proliferation in the hippocampus of S100b transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(12):5359-63.
1993: Bruce Lamb; Sangram S Sisodia; Ann M Lawler; Hilda H Slunt; C A Kitt; William G Kearns; P L Pearson; Donald L Price; John D Gearhart
Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected].
Nature genetics 1993;5(1):22-30.
1993: O Ezaki; J R Flores-Riveros; Klaus kaestner; John D Gearhart; M Daniel Lane
Regulated expression of an insulin-responsive glucose transporter (GLUT4) minigene in 3T3-L1 adipocytes and transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3348-52.
1993: L E Urven; D E Weng; A L Schumaker; John D Gearhart; John R McCarrey
Differential gene expression in fetal mouse germ cells.
Biology of reproduction 1993;48(3):564-74.
1992: Y Wang; Jennifer P Macke; Shannath L Merbs; Donald J Zack; B Klaunberg; J Bennett; John D Gearhart; Jeremy Nathans
A locus control region adjacent to the human red and green visual pigment genes.
Neuron 1992;9(3):429-40.
1991: Gregg L Semenza; Stephen Thomas Koury; M K Nejfelt; John D Gearhart; S E Antonarakis
Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8725-9.
1991: Asad Umar; P A Schweitzer; N S Levy; John D Gearhart; Patricia J Gearhart
Mutation in a reporter gene depends on proximity to and transcription of immunoglobulin variable transgenes.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):4902-6.
1991: Shannon Fisher; John D Gearhart; M L Oster-Granite
Expression of the amyloid precursor protein gene in mouse oocytes and embryos.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(5):1779-82.
1991: Donald J Zack; J Bennett; Y Wang; C Davenport; B Klaunberg; John D Gearhart; Jeremy Nathans
Unusual topography of bovine rhodopsin promoter-lacZ fusion gene expression in transgenic mouse retinas.
Neuron 1991;6(2):187-99.
1991: Joseph T Coyle; M L Oster-Granite; Roger H Reeves; Christine F Hohmann; P Corsi; John D Gearhart
Down syndrome and the trisomy 16 mouse: impact of gene imbalance on brain development and aging.
Research publications - Association for Research in Nervous and Mental Disease 1991;69():85-99.
1991: Don W Cleveland; Mervyn Monteiro; Philip C Wong; S R Gill; John D Gearhart; Paul N Hoffman
Involvement of neurofilaments in the radial growth of axons.
Journal of cell science. Supplement 1991;15():85-95.
1990: MARIAN DAMEWOOD; J S Hesla; William D Schlaff; M Hubbard; John D Gearhart; John A Rock
Effect of serum from patients with minimal to mild endometriosis on mouse embryo development in vitro.
Fertility and sterility 1990;54(5):917-20.
1990: Mervyn Monteiro; Paul N Hoffman; John D Gearhart; Don W Cleveland
Expression of NF-L in both neuronal and nonneuronal cells of transgenic mice: increased neurofilament density in axons without affecting caliber.
The Journal of cell biology 1990;111(4):1543-57.
1990: Roger H Reeves; M R Crowley; B F O'Hara; John D Gearhart
Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse chromosome 16.
Genomics 1990;8(1):141-8.
1990: Gregg L Semenza; R C Dureza; M D Traystman; John D Gearhart; S E Antonarakis
Human erythropoietin gene expression in transgenic mice: multiple transcription initiation sites and cis-acting regulatory elements.
Molecular and cellular biology 1990;10(3):930-8.
1989: Roger H Reeves; John D Gearhart; N B Hecht; P Yelick; P Johnson; S J O'Brien
Mapping of PRM1 to human chromosome 16 and tight linkage of Prm-1 and Prm-2 on mouse chromosome 16.
The Journal of heredity 1989;80(6):442-6.
1989: B F O'Hara; Shannon Fisher; M L Oster-Granite; John D Gearhart; Roger H Reeves
Developmental expression of the amyloid precursor protein, growth-associated protein 43, and somatostatin in normal and trisomy 16 mice.
Brain research. Developmental brain research 1989;49(2):300-4.
1989: J A DeLoia; Robert D Burk; John D Gearhart
Developmental regulation of hepatitis B surface antigen expression in two lines of hepatitis B virus transgenic mice.
Journal of virology 1989;63(9):4069-73.
1989: Gregg L Semenza; M D Traystman; John D Gearhart; S E Antonarakis
Polycythemia in transgenic mice expressing the human erythropoietin gene.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2301-5.
1989: S L Marban; J A DeLoia; John D Gearhart
Hyperinsulinemia in transgenic mice carrying multiple copies of the human insulin gene.
Developmental genetics 1989;10(5):356-64.
1989: David Weng; R A Morgan; John D Gearhart
Estimates of mRNA abundance in the mouse blastocyst based on cDNA library analysis.
Molecular reproduction and development 1989;1(4):233-41.
1988: B F O'Hara; C Bendotti; Roger H Reeves; M L Oster-Granite; Joseph T Coyle; John D Gearhart
Genetic mapping and analysis of somatostatin expression in Snell dwarf mice.
Brain research 1988;464(4):283-92.
1988: Roger H Reeves; B F O'Hara; william pavan; John D Gearhart; Otto Haller
Genetic mapping of the Mx influenza virus resistance gene within the region of mouse chromosome 16 that is homologous to human chromosome 21.
Journal of virology 1988;62(11):4372-5.
1988: J T Coyle; M L Oster-Granite; Roger H Reeves; John D Gearhart
Down syndrome, Alzheimer's disease and the trisomy 16 mouse.
Trends in neurosciences 1988;11(9):390-4.
1988: C Bendotti; Gianluigi Forloni; R A Morgan; B F O'Hara; M L Oster-Granite; Roger H Reeves; John D Gearhart; Joseph T Coyle
Neuroanatomical localization and quantification of amyloid precursor protein mRNA by in situ hybridization in the brains of normal, aneuploid, and lesioned mice.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(10):3628-32.
1988: Robert D Burk; J A DeLoia; Mostafa El Awady; John D Gearhart
Tissue preferential expression of the hepatitis B virus (HBV) surface antigen gene in two lines of HBV transgenic mice.
Journal of virology 1988;62(2):649-54.
1987: Roger H Reeves; Nikolaos K Robakis; M L Oster-Granite; Henryk M Wisniewski; Joseph T Coyle; John D Gearhart
Genetic linkage in the mouse of genes involved in Down syndrome and Alzheimer's disease in man.
Brain research 1987;388(3):215-21.
1987: J A DeLoia; John D Gearhart
Transgenic mice in the study of development.
Mead Johnson Symposium on Perinatal and Developmental Medicine 1987;(29):41-6.
1987: John D Gearhart; M L Oster-Granite; Roger H Reeves; Joseph T Coyle
Developmental consequences of autosomal aneuploidy in mammals.
Developmental genetics 1987;8(4):249-65.
1987: Mario Saltarelli; Gianluigi Forloni; M L Oster-Granite; John D Gearhart; Joseph T Coyle
Neurochemical characterization of embryonic brain development in trisomy 19 (Ts19) mice: implications of selective deficits observed for abnormal neural development in aneuploidy.
Developmental genetics 1987;8(4):267-79.
1987: Roger H Reeves; D Gallahan; B F O'Hara; R Callahan; John D Gearhart
Genetic mapping of Prm-1, Igl-1, Smst, Mtv-6, Sod-1, and Ets-2 and localization of the Down syndrome region on mouse chromosome 16.
Cytogenetics and cell genetics 1987;44(2-3):76-81.
1986: John D Gearhart; M T Davisson; M L Oster-Granite
Autosomal aneuploidy in mice: generation and developmental consequences.
Brain research bulletin 1986;16(6):789-801.
1986: Roger H Reeves; John D Gearhart; J W Littlefield
Genetic basis for a mouse model of Down syndrome.
Brain research bulletin 1986;16(6):803-14.
1986: John D Gearhart; Harvey S Singer; Timothy H Moran; Michael Tiemeyer; M L Oster-Granite; J T Coyle
Mouse chimeras composed of trisomy 16 and normal (2N) cells: preliminary studies.
Brain research bulletin 1986;16(6):815-24.
1986: J T Coyle; M L Oster-Granite; John D Gearhart
The neurobiologic consequences of Down syndrome.
Brain research bulletin 1986;16(6):773-87.
1986: Dennis Watson; M J McWilliams-Smith; C Kozak; Roger H Reeves; John D Gearhart; M F Nunn; W Nash; J R Fowle; P Duesberg; T S Papas
Conserved chromosomal positions of dual domains of the ets protooncogene in cats, mice, and humans.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(6):1792-6.
1985: John A Rock; Howard Zacur; MARIAN DAMEWOOD; William D Schlaff; John D Gearhart; T Chang; A Schuetz; G Foster; B R Smith; N B Rosenshein
In vitro fertilization and embryo transfer: the Johns Hopkins Hospital, Baltimore, Maryland.
Journal of in vitro fertilization and embryo transfer : IVF 1985;2(2):110-2.
1984: Harvey S Singer; Michael Tiemeyer; J C Hedreen; John D Gearhart; J T Coyle
Morphologic and neurochemical studies of embryonic brain development in murine trisomy 16.
Brain research 1984;317(2):155-66.
1983: K M Murphy; Robert Gould; M L Oster-Granite; John D Gearhart; Solomon H Snyder
Phorbol ester receptors: autoradiographic identification in the developing rat.
Science (New York, N.Y.) 1983;222(4627):1036-8.
1981: M L Oster-Granite; John D Gearhart
Cell lineage analysis of cerebellar Purkinje cells in mouse chimeras.
Developmental biology 1981;85(1):199-208.
1981: John D Gearhart; M L Oster-Granite; J M Musser
Immunoreactivity of the two common allozymes of murine glucosephosphate isomerase.
Biochemical genetics 1981;19(5-6):445-55.
1981: John D Gearhart; M L Oster-Granite
Reproduction in a population of chimeric mice: relationship of chromosomal sex to functional germ cells and proportions of chimeric components in several tissues.
Biology of reproduction 1981;24(4):713-22.
1981: John D Gearhart; M L Oster-Granite
Age-related pigmentation changes in the coats of allophenic mice.
The Journal of heredity 1981;72(1):3-5.
1980: John D Gearhart; M L Oster-Granite
Glucosephosphate isomerase distribution during oocyte maturation and early embryologic stages of the mouse.
Biology of reproduction 1980;23(4):837-45.
1980: M L Oster-Granite; John D Gearhart
Immunofluorescence and histochemical localization of glucosephosphate isomerase in neural tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1980;28(3):250-4.
1980: John D Gearhart; M L Oster-Granite
An immunofluorescence procedure for the tissue localization of glucosephosphate isomerase.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1980;28(3):245-9.
1979: John D Gearhart; M L Oster-Granite; L Guth
Histological changes after transection of the spinal cord of fetal and neonatal mice.
Experimental neurology 1979;66(1):1-15.
1978: John D Gearhart; M L Oster-Granite
Antibodies to allozymes as potential cell markers for chimeric mouse studies.
Basic life sciences 1978;12():111-22.
1977: Michael J Dewey; John D Gearhart; B Mintz
Cell surface antigens of totipotent mouse teratocarcinoma cells grown in vivo: their relation to embryo, adult, and tumor antigens.
Developmental biology 1977;55(2):359-74.
1975: John D Gearhart; B Mintz
Creatine kinase, myokinase, and acetylcholinesterase activities in muscle-forming primary cultures of mouse teratocarcinoma cells.
Cell 1975;6(1):61-6.
1974: John D Gearhart; B Mintz
Contact-mediated myogenesis and increased acetylcholinesterase activity in primary cultures of mouse teratocarcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(5):1734-8.
1973: B Mintz; John D Gearhart; A O Guymont
Phytohemagglutinin-mediated blastomere aggregation and development of allophenic mice.
Developmental biology 1973;31(1):195-9.
1973: B Mintz; John D Gearhart
Subnormal zona pellucida change in parthenogenetic mouse embryos.
Developmental biology 1973;31(1):178-84.
1972: John D Gearhart; B Mintz
Glucosephosphate isomerase subunit-reassociation tests for maternal-fetal and fetal-fetal cell fusion in the mouse placenta.
Developmental biology 1972;29(1):55-64.
1972: John D Gearhart; B Mintz
Clonal origins of somites and their muscle derivatives: evidence from allophenic mice.
Developmental biology 1972;29(1):27-37.
1971: John D Gearhart; R J MacIntyre
Lack of intercellular suppression of position-effect variegation by supernumerary Y chromosomes during cell differentiation in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(1):13-5.
1970: John D Gearhart; R J MacIntyre
Quantification of drosopterins in single eyes of Drosophila melanogaster.
Analytical biochemistry 1970;37(1):21-5.