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Rolf Gebhardt

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Madlen Matz-Soja; Amalya Hovhannisyan; Rolf Gebhardt
Hedgehog signalling pathway in adult liver: a major new player in hepatocyte metabolism and zonation?
Claudia Merkwitz; Michiharu Sakurai; Jan Böttger; Rolf Gebhardt; Paul Lochhead; Madlen Matz-Soja; Albert M Ricken
Dual origin, development, and fate of bovine pancreatic islets.
Rolf Gebhardt; Paul J Coffer
Hepatic autophagy is differentially regulated in periportal and pericentral zones - a general mechanism relevant for other tissues?

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2013: Madlen Matz-Soja; Amalya Hovhannisyan; Rolf Gebhardt
Hedgehog signalling pathway in adult liver: a major new player in hepatocyte metabolism and zonation?
Medical hypotheses 2013;80(5):589-94.
2013: Claudia Merkwitz; Michiharu Sakurai; Jan Böttger; Rolf Gebhardt; Paul Lochhead; Madlen Matz-Soja; Albert M Ricken
Dual origin, development, and fate of bovine pancreatic islets.
Journal of anatomy 2013;222(3):358-71.
2013: Rolf Gebhardt; Paul J Coffer
Hepatic autophagy is differentially regulated in periportal and pericentral zones - a general mechanism relevant for other tissues?
Cell communication and signaling : CCS 2013;11(1):21.
2012: Stefanie Braun; Rainer Baran-Schmidt; Rolf Gebhardt; Alan Hipkiss; Amalya Hovhannisyan; Jürgen Meixensberger; Antje Mueller; Henry Oppermann; Christof Renner; Joachim Thiery; Frank Gaunitz
Hedgehog signaling in glioblastoma multiforme.
Cancer biology & therapy 2012;13(7):487-95.
2012: Sebastian Vlaic; Sebastian Zellmer; Reinhard Guthke; Jörg Linde; Eugenia Marbach; Madlen Matz-Soja; Anke Meyer-Baese; Wolfgang Schmidt-Heck; Rolf Gebhardt
The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes.
BMC systems biology 2012;6():147.
2012: Michael Schaab; Juergen Scheller; Joachim Thiery; Marcin Nowicki; Stefan Rose-John; Ulf Anderegg; Rolf Gebhardt; Henriette Kausch; Juergen Klammt; Juergen Kratzsch
Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action.
PloS one 2012;7(4):e34787.
2011: Mandy Eibisch; Beate Fuchs; Rolf Gebhardt; Rosmarie Süss; Sebastian Zellmer; Jürgen Schiller
Phosphatidylcholine dimers can be easily misinterpreted as cardiolipins in complex lipid mixtures: a matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of lipids from hepatocytes.
Rapid communications in mass spectrometry : RCM 2011;25(18):2619-26.
2011: Ansgar Asperger; Christof Renner; Mandy Menzel; Rolf Gebhardt; Jürgen Meixensberger; Frank Gaunitz
Identification of factors involved in the anti-tumor activity of carnosine on glioblastomas using a proteomics approach.
Cancer investigation 2011;29(4):272-81.
2010: Sebastian Zellmer; Wolfgang Schmidt-Heck; Patricio Godoy; Honglei Weng; Christoph Meyer; Thomas Lehmann; Titus Sparna; Wiebke Schormann; Seddik Hammad; Clemens Kreutz; Jens Timmer; Fritz von Weizsäcker; Petra A Thürmann; Irmgard Merfort; Reinhard Guthke; Steven Dooley; Jan G Hengstler; Rolf Gebhardt
Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes.
Hepatology (Baltimore, Md.) 2010;52(6):2127-36.
2010: Robert Koesters; Brigitte Kaissling; Michel LeHir; Nicolas Picard; Franziska Theilig; Rolf Gebhardt; Adam B Glick; Brunhilde Hähnel; Hiltraud Hosser; Hermann-Josef Gröne; Wilhelm Kriz
Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells.
The American journal of pathology 2010;177(2):632-43.
2010: Sandra Halwachs; Cathleen Lakoma; Rolf Gebhardt; Ingo Schäfer; Peter Seibel; Walther Honscha
Dioxin mediates downregulation of the reduced folate carrier transport activity via the arylhydrocarbon receptor signalling pathway.
Toxicology and applied pharmacology 2010;246(1-2):100-6.
2010: Stefan Hoehme; Marc Brulport; Alexander Bauer; Essam Bedawy; Wiebke Schormann; Matthias Hermes; Verena Puppe; Rolf Gebhardt; Sebastian Zellmer; Michael Schwarz; Ernesto Bockamp; Tobias Timmel; Jan G Hengstler; Dirk Drasdo
Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(23):10371-6.
2010: Rolf Gebhardt; Katja S Lerche; Frank Götschel; Robert Günther; Jens Kolander; Lars Teich; Sebastian Zellmer; Hans-Jörg Hofmann; Kurt Eger; Andreas Hecht; Frank Gaunitz
4-Aminoethylamino-emodin--a novel potent inhibitor of GSK-3beta--acts as an insulin-sensitizer avoiding downstream effects of activated beta-catenin.
Journal of cellular and molecular medicine 2010;14(6A):1276-93.
2010: Christof Renner; Ansgar Asperger; Anne Seyffarth; Jürgen Meixensberger; Rolf Gebhardt; Frank Gaunitz
Carnosine inhibits ATP production in cells from malignant glioma.
Neurological research 2010;32(1):101-5.
2010: Sanja Pavlica; Rolf Gebhardt
Protective effects of flavonoids and two metabolites against oxidative stress in neuronal PC12 cells.
Life sciences 2010;86(3-4):79-86.
2010: Elke Ueberham; Jan Böttger; Uwe Ueberham; Jens Grosche; Rolf Gebhardt
Response of sinusoidal mouse liver cells to choline-deficient ethionine-supplemented diet.
Comparative hepatology 2010;9():8.
2010: Inge Lindner; Nasr Hemdan; Martin Buchold; Klaus Huse; Marina Bigl; Ilka Oerlecke; Albert Ricken; Frank Gaunitz; Ulrich Sack; Andreas Naumann; Margrit Hollborn; Dietmar Thal; Rolf Gebhardt; Gerd Birkenmeier
Alpha2-macroglobulin inhibits the malignant properties of astrocytoma cells by impeding beta-catenin signaling.
Cancer research 2010;70(1):277-87.
2010: Antje Garten; S Petzold; A Barnikol-Oettler; Antje Körner; W E Thasler; Jürgen Kratzsch; Wieland Kiess; Rolf Gebhardt
Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes.
Biochemical and biophysical research communications 2010;391(1):376-81.
2010: Sanja Pavlica; Rolf Gebhardt
Comparison of uptake and neuroprotective potential of seven zinc-salts.
Neurochemistry international 2010;56(1):84-93.
2010: Rolf Gebhardt; Amalya Hovhannisyan
Organ patterning in the adult stage: the role of Wnt/beta-catenin signaling in liver zonation and beyond.
Developmental dynamics : an official publication of the American Association of Anatomists 2010;239(1):45-55.
2009: Amalya Hovhannisyan; Madlen Matz; Rolf Gebhardt
From teratogens to potential therapeutics: natural inhibitors of the Hedgehog signaling network come of age.
Planta medica 2009;75(13):1371-80.
2009: Sebastian Zellmer; Stephan Sickinger; Wolfgang Schmidt-Heck; Reinhard Guthke; Rolf Gebhardt
Heterogeneous expression of suppressor of cytokine signalling 2 (SOCS-2) in liver tissue.
Journal of anatomy 2009;215(2):176-83.
2009: Sanja Pavlica; Frank Gaunitz; Rolf Gebhardt
Comparative in vitro toxicity of seven zinc-salts towards neuronal PC12 cells.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(4):653-9.
2009: Rolf Gebhardt
Prevention of cadmium-induced toxicity in liver-derived cells by the combination preparation Hepeel(®).
Environmental toxicology and pharmacology 2009;27(3):402-9.
2009: Karoline Leonhardt; Rolf Gebhardt; Joachim Mössner; Svetlana Lutsenko; Daniel Huster
Functional interactions of Cu-ATPase ATP7B with cisplatin and the role of ATP7B in the resistance of cells to the drug.
The Journal of biological chemistry 2009;284(12):7793-802.
2009: Claudia Wierzchacz; Enis Su; Jens Kolander; Rolf Gebhardt
Differential inhibition of matrix metalloproteinases-2, -9, and -13 activities by selected anthraquinones.
Planta medica 2009;75(4):327-9.
2009: Lusine Danielyan; Sebastian Zellmer; Stefan Sickinger; Genrich V Tolstonog; Jürgen Salvetter; Ali Lourhmati; Dieter Reissig; Cristoph H Gleiter; Rolf Gebhardt; Gayane H Buniatian
Keratinocytes as depository of ammonium-inducible glutamine synthetase: age- and anatomy-dependent distribution in human and rat skin.
PloS one 2009;4(2):e4416.
2008: Felix Glahn; Wolfgang Schmidt-Heck; Sebastian Zellmer; Reinhard Guthke; Jan Wiese; Klaus Golka; Roland Hergenröder; Gisela H Degen; Thomas Lehmann; Matthias Hermes; Wiebke Schormann; Marc Brulport; Alexander Bauer; Essam Bedawy; Rolf Gebhardt; Jan G Hengstler; Heidi Foth
Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors.
Archives of toxicology 2008;82(8):513-24.
2008: Steven Dooley; Jafar Hamzavi; Loredana Ciuclan; Patricio Godoy; Iryna Ilkavets; Sabrina Ehnert; Elke Ueberham; Rolf Gebhardt; Stephan Kanzler; Andreas Geier; Katja Breitkopf; Honglei Weng; Peter R Mertens
Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage.
Gastroenterology 2008;135(2):642-59.
2008: Elke Ueberham; Ricco Lindner; Manja Kamprad; Rico Hiemann; Nadja Hilger; Barbara Woithe; Doris Mahn; Michael Cross; Ulrich Sack; Rolf Gebhardt; Thomas Arendt; Uwe Ueberham
Oval cell proliferation in p16INK4a expressing mouse liver is triggered by chronic growth stimuli.
Journal of cellular and molecular medicine 2008;12(2):622-38.
2008: Thore Santel; Gabi Pflug; Nasr Hemdan; Angelika Schäfer; Marcus Hollenbach; Martin Buchold; Anja Hintersdorf; Inge Lindner; Andreas Otto; Marina Bigl; Ilka Oerlecke; Antje Hutschenreuter; Ulrich Sack; Klaus Huse; Marco Groth; Claudia Birkemeyer; Wolfgang Schellenberger; Rolf Gebhardt; Mathias Platzer; Thomas Weiss; Mookambeswaran A Vijayalakshmi; Monika Krüger; Antje Hutschenreuther; Gerd Birkenmeier
Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity.
PloS one 2008;3(10):e3508.
2008: Madeleine Austinat; Ruediger Dunsch; Christian Wittekind; Andrea Tannapfel; Rolf Gebhardt; Frank Gaunitz
Correlation between beta-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma.
Molecular cancer 2008;7():21.
2007: Hong-lei Weng; Loredana Ciuclan; Yan Liu; Jafar Hamzavi; Patricio Godoy; Haristi Gaitantzi; Stefan Kanzler; Rainer Heuchel; Uwe Ueberham; Rolf Gebhardt; Katja Breitkopf; Steven Dooley
Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes.
Hepatology (Baltimore, Md.) 2007;46(4):1257-70.
2007: Shmuel E Cohen; Efi Kokkotou; Sudha B Biddinger; Tatsuya Kondo; Rolf Gebhardt; Jürgen Kratzsch; Christos S Mantzoros; C Ronald Kahn
High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice.
The Journal of biological chemistry 2007;282(32):23672-8.
2007: Elke Ueberham; Thomas Aigner; Uwe Ueberham; Rolf Gebhardt
E-cadherin as a reliable cell surface marker for the identification of liver specific stem cells.
Journal of molecular histology 2007;38(4):359-68.
2007: Stefan Höhme; Jan G Hengstler; Marc Brulport; Marc Schäfer; Alexander Bauer; Rolf Gebhardt; Dirk Drasdo
Mathematical modelling of liver regeneration after intoxication with CCl(4).
Chemico-biological interactions 2007;168(1):74-93.
2007: Lusine Danielyan; Genrich Tolstonog; Peter Traub; Juergen Salvetter; Christoph H Gleiter; Dieter Reisig; Rolf Gebhardt; Gayane H Buniatian
Colocalization of glial fibrillary acidic protein, metallothionein, and MHC II in human, rat, NOD/SCID, and nude mouse skin keratinocytes and fibroblasts.
The Journal of investigative dermatology 2007;127(3):555-63.
2007: Rolf Gebhardt; Alicja Baldysiak-Figiel; Vera Krügel; Elke Ueberham; Frank Gaunitz
Hepatocellular expression of glutamine synthetase: an indicator of morphogen actions as master regulators of zonation in adult liver.
Progress in histochemistry and cytochemistry 2007;41(4):201-66.
2006: Martijn B A van Doorn; Sonia M S Espirito Santo; Piet Meijer; I M C Kamerling; Rik C Schoemaker; Verena M Dirsch; Angelika M Vollmar; Thomas Haffner; Rolf Gebhardt; Adam Cohen; Hans M G Princen; Jacobus Burggraaf
Effect of garlic powder on C-reactive protein and plasma lipids in overweight and smoking subjects.
The American journal of clinical nutrition 2006;84(6):1324-9.
2006: U Klingmüller; A Bauer; S Bohl; P J Nickel; K Breitkopf; S Dooley; S Zellmer; C Kern; I Merfort; T Sparna; J Donauer; G Walz; M Geyer; C Kreutz; Matthias Hermes; F Götschel; A Hecht; D Walter; L Egger; K Neubert; C Borner; M Brulport; W Schormann; C Sauer; F Baumann; R Preiss; S MacNelly; P Godoy; E Wiercinska; Loredana Ciuclan; Jeanett Edelmann; K Zeilinger; M Heinrich; Uli Zanger; Rolf Gebhardt; T Maiwald; R Heinrich; J Timmer; F von Weizsäcker; Jan G Hengstler
Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways.
Systems biology 2006;153(6):433-47.
2006: Max Werth; Rolf Gebhardt; Frank Gaunitz
Hepatic expression of glutamine synthetase in rats is controlled by STAT5 and TCF transcription factors.
Hepatology (Baltimore, Md.) 2006;44(4):967-75.
2006: Rolf Gebhardt; Elke Ueberham
Zonal gene expression in murine liver: Are tumors helping us to solve the mystery?
Hepatology (Baltimore, Md.) 2006;44(2):512; author reply 512-3.
2006: Doreen Schlupper; Sabine Giesa; Rolf Gebhardt
Influence of biotransformation of luteolin, luteolin 7-O-glucoside, 3',4'-dihydroxyflavone and apigenin by cultured rat hepatocytes on antioxidative capacity and inhibition of EGF receptor tyrosine kinase activity.
Planta medica 2006;72(7):596-603.
2005: Sanja Pavlica; Rolf Gebhardt
Protective effects of ellagic and chlorogenic acids against oxidative stress in PC12 cells.
Free radical research 2005;39(12):1377-90.
2005: E Arendt; Uwe Ueberham; R Bittner; Rolf Gebhardt; Elke Ueberham
Enhanced matrix degradation after withdrawal of TGF-beta1 triggers hepatocytes from apoptosis to proliferation and regeneration.
Cell proliferation 2005;38(5):287-99.
2005: Uwe Ueberham; Elke Ueberham; Martina K Brückner; Gudrun Seeger; Ulrich Gärtner; Hildegard Gruschka; Rolf Gebhardt; Thomas Arendt
Inducible neuronal expression of transgenic TGF-beta1 in vivo: dissection of short-term and long-term effects.
The European journal of neuroscience 2005;22(1):50-64.
2005: Marianna Kruithof-de Julio; Wil T Labruyère; Jan M Ruijter; Jacqueline L M Vermeulen; Vesna Stanulović; Jan M P Stallen; Alicja Baldysiak-Figiel; Rolf Gebhardt; Wouter H Lamers; Theodorus B M Hakvoort
The RL-ET-14 cell line mediates expression of glutamine synthetase through the upstream enhancer/promoter region.
Journal of hepatology 2005;43(1):126-31.
2005: Frank Gaunitz; Danilo Deichsel; Kerstin Heise; Max Werth; Ulf Anderegg; Rolf Gebhardt
An intronic silencer element is responsible for specific zonal expression of glutamine synthetase in the rat liver.
Hepatology (Baltimore, Md.) 2005;41(6):1225-32.
2005: Ulrich Sack; Astrid Hirth; Benjamin Funke; Katharina Wiedemeyer; Franziska Lange; Michael Tröltzsch; Andrea Tannapfel; Rolf Gebhardt; Frank Emmrich; Joerg Lehmann
A novel model of fibroblast-mediated cartilage destruction.
Scandinavian journal of immunology 2005;61(1):18-28.
2004: Lars Teich; Katja Scarlett Daub; Vera Krügel; Ludwig Nissler; Rolf Gebhardt; Kurt Eger
Synthesis and biological evaluation of new derivatives of emodin.
Bioorganic & medicinal chemistry 2004;12(22):5961-71.
2004: Christina Ende; Rolf Gebhardt
Inhibition of matrix metalloproteinase-2 and -9 activities by selected flavonoids.
Planta medica 2004;70(10):1006-8.
2004: Ludwig Nissler; Rolf Gebhardt; Stefan Berger
Flavonoid binding to a multi-drug-resistance transporter protein: an STD-NMR study.
Analytical and bioanalytical chemistry 2004;379(7-8):1045-9.
2004: K Meyer; Elke Ueberham; Rolf Gebhardt
Influence of organosulphur compounds from garlic on the secretion of matrix metalloproteinases and their inhibitor TIMP-1 by cultured HUVEC cells.
Cell biology and toxicology 2004;20(4):253-60.
2004: Elke Ueberham; Elisabeth Arendt; Michael Starke; Renate Bittner; Rolf Gebhardt
Reduction and expansion of the glutamine synthetase expressing zone in livers from tetracycline controlled TGF-beta1 transgenic mice and multiple starved mice.
Journal of hepatology 2004;41(1):75-81.
2004: Holger A Scheidt; André Pampel; Ludwig Nissler; Rolf Gebhardt; Daniel Huster
Investigation of the membrane localization and distribution of flavonoids by high-resolution magic angle spinning NMR spectroscopy.
Biochimica et biophysica acta 2004;1663(1-2):97-107.
2004: Frank Gaunitz; Kerstin Heise; Rolf Gebhardt
A silencer element in the first intron of the glutamine synthetase gene represses induction by glucocorticoids.
Molecular endocrinology (Baltimore, Md.) 2004;18(1):63-9.
2003: Rolf Gebhardt
Variable influence of kaempferol and myricetin on in vitro hepatocellular cholesterol biosynthesis.
Planta medica 2003;69(12):1071-4.
2003: Rolf Gebhardt; Jan G Hengstler; Dieter Müller; Reinhild Glöckner; Peter Buenning; Britta Laube; Eva Schmelzer; Martina Ullrich; Dietmar Utesch; Nicola Hewitt; Michael Ringel; Beate Reder Hilz; Augustinus Bader; Angelika Langsch; Thomas Koose; Hans-Joerg burgerh; Jochen Maas; Franz Oesch
New hepatocyte in vitro systems for drug metabolism: metabolic capacity and recommendations for application in basic research and drug development, standard operation procedures.
Drug metabolism reviews 2003;35(2-3):145-213.
2003: Elke Ueberham; Rainer Löw; Uwe Ueberham; Kai Schönig; Hermann Bujard; Rolf Gebhardt
Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis.
Hepatology (Baltimore, Md.) 2003;37(5):1067-78.
2003: Rolf Gebhardt
Antioxidative, antiproliferative and biochemical effects in HepG2 cells of a homeopathic remedy and its constituent plant tinctures tested separately or in combination.
Arzneimittel-Forschung 2003;53(12):823-30.
2002: Sandra Loeppen; Daniela Schneider; Frank Gaunitz; Rolf Gebhardt; Raffael Kurek; Albrecht Buchmann; Michael Schwarz
Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital.
Cancer research 2002;62(20):5685-8.
2002: Rolf Gebhardt
Prevention of taurolithocholate-induced hepatic bile canalicular distortions by HPLC-characterized extracts of artichoke (Cynara scolymus) leaves.
Planta medica 2002;68(9):776-9.
2002: Frank Gaunitz; Kerstin Heise; Robert Schumann; Rolf Gebhardt
Glucocorticoid induced expression of glutamine synthetase in hepatoma cells.
Biochemical and biophysical research communications 2002;296(4):1026-32.
2002: Rolf Gebhardt
Inhibition of cholesterol biosynthesis in HepG2 cells by artichoke extracts is reinforced by glucosidase pretreatment.
Phytotherapy research : PTR 2002;16(4):368-72.
2002: Rolf Gebhardt
Oxidative stress, plant-derived antioxidants and liver fibrosis.
Planta medica 2002;68(4):289-96.
2002: Ulf D Renner; Georgios Piperopoulos; Rolf Gebhardt; Gerhard Ehninger; Klaus-Peter Zeller
The oxidative biotransformation of losoxantrone (CI-941).
Drug metabolism and disposition: the biological fate of chemicals 2002;30(4):464-78.
2002: Pavel Kosina; Vladimír Kren; Rolf Gebhardt; Frantisek Grambal; Jitka Ulrichová; Daniela Walterová
Antioxidant properties of silybin glycosides.
Phytotherapy research : PTR 2002;16 Suppl 1():S33-9.
2002: Susanne Neumann; Klaus Huse; Robert Semrau; Anno Diegeler; Rolf Gebhardt; Gayane H Buniatian; Gerhard Scholz
Aldosterone and D-glucose stimulate the proliferation of human cardiac myofibroblasts in vitro.
Hypertension 2002;39(3):756-60.
2002: Rolf Gebhardt
Liver epithelial cell culture.
Methods in molecular biology (Clifton, N.J.) 2002;188():53-63.
2002: Rolf Gebhardt
Co-cultivation of liver epithelial cells with hepatocytes.
Methods in molecular biology (Clifton, N.J.) 2002;188():337-46.
2002: G Glässer; Eva Ulrike Graefe; F Struck; Markus Veit; Rolf Gebhardt
Comparison of antioxidative capacities and inhibitory effects on cholesterol biosynthesis of quercetin and potential metabolites.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2002;9(1):33-40.
2001: A Y Surovoi; Elena A Sukhacheva; M Y Wert; F O Yarovinsky; E S Zeinalova; Frank Gaunitz; E Uberahm; Rolf Gebhardt
Obtaining of monoclonal antibodies by means of DNA immunization.
Doklady. Biochemistry and biophysics 2001;379():255-6.
2001: Frank Gaunitz; S Weber; L Scheja; Rolf Gebhardt
Identification of a cis-acting element and a novel trans-acting factor of the glutamine synthetase gene in liver cells.
Biochemical and biophysical research communications 2001;284(2):377-83.
2001: Rolf Gebhardt
Anticholestatic activity of flavonoids from artichoke (Cynara scolymus L.) and of their metabolites.
Medical science monitor : international medical journal of experimental and clinical research 2001;7 Suppl 1():316-20.
2001: Gayane H Buniatian; Hans-Jürgen Hartmann; Peter Traub; Ulrich Weser; Heinrich Wiesinger; Rolf Gebhardt
Acquisition of blood--tissue barrier--supporting features by hepatic stellate cells and astrocytes of myofibroblastic phenotype. Inverse dynamics of metallothionein and glial fibrillary acidic protein expression.
Neurochemistry international 2001;38(5):373-83.
2001: Sebastian Zellmer; A Surovoy; Frank Gaunitz; Jürgen Salvetter; Rolf Gebhardt; Dieter Reissig
Transfection of normal human epidermal keratinocytes with lipid/dna complexes in vitro.
Journal of liposome research 2001;11(1):43-54.
2001: Sebastian Zellmer; Frank Gaunitz; Jürgen Salvetter; A Surovoy; Dieter Reissig; Rolf Gebhardt
Long-term expression of foreign genes in normal human epidermal keratinocytes after transfection with lipid/DNA complexes.
Histochemistry and cell biology 2001;115(1):41-7.
2000: W Haupt; Frank Gaunitz; Rolf Gebhardt
Post-transcriptional inhibition of glutamine synthetase induction in rat liver epithelial cells exerted by conditioned medium from rat hepatocytes.
Life sciences 2000;67(26):3191-8.
2000: G Glässer; Rolf Gebhardt; Frank Gaunitz
Heterogeneous expression of mRNA in rat liver lobules as detected by differential display.
Histochemistry and cell biology 2000;114(5):357-62.
2000: Rolf Gebhardt
In vitro screening of plant extracts and phytopharmaceuticals: novel approaches for the elucidation of active compounds and their mechanisms.
Planta medica 2000;66(2):99-105.
1999: Gayane H Buniatian; Rolf Gebhardt; Peter Traub; Dieter Mecke; Hartmut Osswald
Dynamics of glial fibrillary acidic protein distribution in cultured glomerular podocytes and mesangial cells of the rat kidney.
Biology of the cell / under the auspices of the European Cell Biology Organization 1999;91(9):675-84.
1999: Gayane H Buniatian; Rolf Gebhardt; Dieter Mecke; Peter Traub; Heinrich Wiesinger
Common myofibroblastic features of newborn rat astrocytes and cirrhotic rat liver stellate cells in early cultures and in vivo.
Neurochemistry international 1999;35(4):317-27.
1999: Gerd Birkenmeier; F Struck; Rolf Gebhardt
Clearance mechanism of prostate specific antigen and its complexes with alpha2-macroglobulin and alpha1-antichymotrypsin.
The Journal of urology 1999;162(3 Pt 1):897-901.
1999: Rolf Gebhardt; C Lippert; A Schneider; J Doehmer
Improved Determination of Drug Metabolism by Perifusion of Recombinant V79 Cells Carrying Human CYP3A4.
Toxicology in vitro : an international journal published in association with BIBRA 1999;13(4-5):639-43.
1999: Doris Mayer; Gayane H Buniatian; Corinna Metzger; Peter Bannasch; Rolf Gebhardt
Dehydroepiandrosterone increases the zone [correction of in zone] of glutamine synthetase-positive hepatocytes in female rat liver: a putative androgenic effect.
Histochemistry and cell biology 1999;111(5):375-80.
1998: Gary M Williams; Michael J Iatropoulos; CX Wang; Alan M Jeffrey; S Thompson; Brian Pittman; M Palasch; Rolf Gebhardt
Nonlinearities in 2-acetylaminofluorene exposure responses for genotoxic and epigenetic effects leading to initiation of carcinogenesis in rat liver.
Toxicological sciences : an official journal of the Society of Toxicology 1998;45(2):152-61.
1998: Rolf Gebhardt
Inhibition of cholesterol biosynthesis in primary cultured rat hepatocytes by artichoke (Cynara scolymus L.) extracts.
The Journal of pharmacology and experimental therapeutics 1998;286(3):1122-8.
1998: Rolf Gebhardt; M Schuler; D Schörner
The spontaneous induction of glutamine synthetase in pig hepatocytes cocultured with RL-ET-14 cells is completely inhibited by trijodothyronine and okadaic acid.
Biochemical and biophysical research communications 1998;246(3):895-8.
1998: Nobuyoshi Shiojiri; J Wada; Rolf Gebhardt
Heterogeneous carbamoylphosphate synthetase I expression in testicular transplants of fetal mouse liver.
European journal of cell biology 1998;75(4):389-92.
1998: W Haupt; W Schrode; Rolf Gebhardt
Conditioned medium from cultured rat hepatocytes completely blocks induction of glutamine synthetase by dexamethasone in several rat liver epithelial cell lines.
Cell biology and toxicology 1998;14(1):69-80.
1998: Rolf Gebhardt; W Schrode; I Eisenmann-Tappe
Cellular characteristics of epithelial cell lines from juvenile rat liver: selective induction of glutamine synthetase by dexamethasone.
Cell biology and toxicology 1998;14(1):55-67.
1998: Takashi Umemura; K Takada; C Schulz; Rolf Gebhardt; Yuji Kurokawa; Gary M Williams
Cell proliferation in the livers of male mice and rats exposed to the carcinogen P-dichlorobenzene: evidence for thresholds.
Drug and chemical toxicology 1998;21(1):57-66.
1998: Rolf Gebhardt
Perifusion culture of hepatocytes.
Methods in molecular biology (Clifton, N.J.) 1998;107():329-39.
1998: Rolf Gebhardt
Isolation of periportal and pericentral hepatocytes.
Methods in molecular biology (Clifton, N.J.) 1998;107():319-28.
1998: Gayane H Buniatian; Peter Traub; Margitta Albinus; G Beckers; Albrecht Buchmann; Rolf Gebhardt; Hartmut Osswald
The immunoreactivity of glial fibrillary acidic protein in mesangial cells and podocytes of the glomeruli of rat kidney in vivo and in culture.
Biology of the cell / under the auspices of the European Cell Biology Organization 1998;90(1):53-61.
1997: Nobuyoshi Shiojiri; T Ohta; K Ogawa; Rolf Gebhardt
Complementary expression of glutamine synthetase and carbamoylphosphate synthetase I in ornithine carbamoyltransferase-deficient mouse liver (spf-ash mouse).
Histochemistry and cell biology 1997;108(6):489-94.
1997: Rolf Gebhardt; M Fausel
Antioxidant and hepatoprotective effects of artichoke extracts and constituents in cultured rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 1997;11(5):669-72.
1997: S Klein; Rolf Gebhardt
Sensitive detection of growth stimulating tumour promoters in perifused primary rat hepatocyte cultures.
Toxicology in vitro : an international journal published in association with BIBRA 1997;11(5):543-7.
1997: Rolf Gebhardt; G Beckers; Frank Gaunitz; W Haupt; D Jonitza; S Klein; L Scheja
Treatment of cirrhotic rats with L-ornithine-L-aspartate enhances urea synthesis and lowers serum ammonia levels.
The Journal of pharmacology and experimental therapeutics 1997;283(1):1-6.
1997: Rolf Gebhardt; Frank Gaunitz
Cell-cell interactions in the regulation of the expression of hepatic enzymes.
Cell biology and toxicology 1997;13(4-5):263-73.
1997: Rolf Gebhardt
Antioxidative and protective properties of extracts from leaves of the artichoke (Cynara scolymus L.) against hydroperoxide-induced oxidative stress in cultured rat hepatocytes.
Toxicology and applied pharmacology 1997;144(2):279-86.
1997: Rolf Gebhardt
Garlic: the key to sophisticated lowering of hepatocellular lipid.
Nutrition (Burbank, Los Angeles County, Calif.) 1997;13(4):379-80.
1997: Kurt Geckeler; Rolf Gebhardt; H Grünwald
Surface modification of polyethylene by plasma grafting with styrene for enhanced biocompatibility.
Die Naturwissenschaften 1997;84(4):150-1.
1997: Frank Gaunitz; C Gaunitz; M Papke; Rolf Gebhardt
Cis-regulatory sequences from the first intron of the rat glutamine synthetase gene are involved in hepatocyte specific expression of the enzyme.
Biological chemistry 1997;378(1):11-8.
1996: Rolf Gebhardt; H Beck
Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures.
Lipids 1996;31(12):1269-76.
1996: Gary M Williams; M J Iatropoulos; C X Wang; N Ali; A Rivenson; L A Peterson; C Schulz; Rolf Gebhardt
Diethylnitrosamine exposure-responses for DNA damage, centrilobular cytotoxicity, cell proliferation and carcinogenesis in rat liver exhibit some non-linearities.
Carcinogenesis 1996;17(10):2253-8.
1996: H Sirma; G M Williams; Rolf Gebhardt
Strain- and sex-specific variations in hepatic glutamine synthetase activity and distribution in rats and mice.
Liver 1996;16(3):166-73.
1996: Gayane H Buniatian; Rolf Gebhardt; D Schrenk; Bernd Hamprecht
Colocalization of three types of intermediate filament proteins in perisinusoidal stellate cells: glial fibrillary acidic protein as a new cellular marker.
European journal of cell biology 1996;70(1):23-32.
1996: Frank Gaunitz; M Papke; Rolf Gebhardt
Transient transfection of primary cultured hepatocytes using CaPO4/DNA precipitation.
BioTechniques 1996;20(5):826-30, 832.
1996: L O Klotz; J Müller; M Fausel; Rolf Gebhardt; Ulrich Weser
Reactivity of lipophilic diSchiff-Base coordinated copper in rat hepatocytes.
Biochemical pharmacology 1996;51(7):919-29.
1996: Rolf Gebhardt; H Wegner; J Alber
Perifusion of co-cultured hepatocytes: optimization of studies on drug metabolism and cytotoxicity in vitro.
Cell biology and toxicology 1996;12(2):57-68.
1996: G Buniatian; B Hamprecht; Rolf Gebhardt
Glial fibrillary acidic protein as a marker of perisinusoidal stellate cells that can distinguish between the normal and myofibroblast-like phenotypes.
Biology of the cell / under the auspices of the European Cell Biology Organization 1996;87(1-2):65-73.
1996: K Bergbauer; Ralf Dringen; Stephan Verleysdonk; Rolf Gebhardt; Bernd Hamprecht; Heinrich Wiesinger
Studies on fructose metabolism in cultured astroglial cells and control hepatocytes: lack of fructokinase activity and immunoreactivity in astrocytes.
Developmental neuroscience 1996;18(5-6):371-9.
1995: Rolf Gebhardt; G M Williams
Glutamine synthetase and hepatocarcinogenesis.
Carcinogenesis 1995;16(8):1673-81.
1995: Rolf Gebhardt
Amplification of palmitate-induced inhibition of cholesterol biosynthesis in cultured rat hepatocytes by garlic-derived organosulfur compounds.
Phytomedicine : international journal of phytotherapy and phytopharmacology 1995;2(1):29-34.
1995: Nobuyoshi Shiojiri; J I Wada; T Tanaka; M Noguchi; M Ito; Rolf Gebhardt
Heterogeneous hepatocellular expression of glutamine synthetase in developing mouse liver and in testicular transplants of fetal liver.
Laboratory investigation; a journal of technical methods and pathology 1995;72(6):740-7.
1995: Jos W R Twisk; M F Hoekman; Willem H Mager; A F Moorman; P A de Boer; L Scheja; Hans M G Princen; Rolf Gebhardt
Heterogeneous expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase genes in the rat liver lobulus.
The Journal of clinical investigation 1995;95(3):1235-43.
1995: Annette Volk; G Michalopoulos; M Weidner; Rolf Gebhardt
Different proliferative responses of periportal and pericentral rat hepatocytes to hepatocyte growth factor.
Biochemical and biophysical research communications 1995;207(2):578-84.
1995: D Schmoll; E Führmann; Rolf Gebhardt; Bernd Hamprecht
Significant amounts of glycogen are synthesized from 3-carbon compounds in astroglial primary cultures from mice with participation of the mitochondrial phosphoenolpyruvate carboxykinase isoenzyme.
European journal of biochemistry / FEBS 1995;227(1-2):308-15.
1994: Katryn Furuya; Rolf Gebhardt; Erin G Schuetz; John D Schuetz
Isolation of rat pgp3 cDNA: evidence for gender and zonal regulation of expression in the liver.
Biochimica et biophysica acta 1994;1219(3):636-44.
1994: Frej Stenbäck; Rolf Gebhardt; H Sirma; J M Garbay; G M Williams
Sequential functional and morphological alterations during hepatocarcinogenesis induced in rats by feeding of a low dose of 2-acetylaminofluorene.
Toxicologic pathology 1994;22(6):620-32.
1994: Rolf Gebhardt; J Reichen
Changes in distribution and activity of glutamine synthetase in carbon tetrachloride-induced cirrhosis in the rat: potential role in hyperammonemia.
Hepatology (Baltimore, Md.) 1994;20(3):684-91.
1994: Rolf Gebhardt; J Alber; H Wegner; Dieter Mecke
Different drug metabolizing capacities in cultured periportal and pericentral hepatocytes.
Biochemical pharmacology 1994;48(4):761-6.
1994: Rolf Gebhardt; H Beck; K G Wagner
Inhibition of cholesterol biosynthesis by allicin and ajoene in rat hepatocytes and HepG2 cells.
Biochimica et biophysica acta 1994;1213(1):57-62.
1994: Laurence Christa; M T Simon; J P Flinois; Rolf Gebhardt; Christian Brechot; C Lasserre
Overexpression of glutamine synthetase in human primary liver cancer.
Gastroenterology 1994;106(5):1312-20.
1994: Dieter Schrenk; Albrecht Buchmann; K Dietz; H P Lipp; H Brunner; H Sirma; Peter A Münzel; Hanspaul Hagenmaier; Rolf Gebhardt; Karl Walter Bock
Promotion of preneoplastic foci in rat liver with 2,3,7,8-tetrachlorodibenzo-p-dioxin, 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin and a defined mixture of 49 polychlorinated dibenzo-p-dioxins.
Carcinogenesis 1994;15(3):509-15.
1994: Rolf Gebhardt; Frank Gaunitz; Dieter Mecke
Heterogeneous (positional) expression of hepatic glutamine synthetase: features, regulation and implications for hepatocarcinogenesis.
Advances in enzyme regulation 1994;34():27-56.
1993: K Mewes; J Blanz; Gerhard Ehninger; Rolf Gebhardt; K P Zeller
Cytochrome P-450-induced cytotoxicity of mitoxantrone by formation of electrophilic intermediates.
Cancer research 1993;53(21):5135-42.
1993: Ralf Dringen; Rolf Gebhardt; Bernd Hamprecht
Glycogen in astrocytes: possible function as lactate supply for neighboring cells.
Brain research 1993;623(2):208-14.
1993: Gary M Williams; Rolf Gebhardt; H Sirma; F Stenbäck
Non-linearity of neoplastic conversion induced in rat liver by low exposures to diethylnitrosamine.
Carcinogenesis 1993;14(10):2149-56.
1993: T Umemura; K Tokumo; H Sirma; Rolf Gebhardt; M C Poirier; Gary M Williams
Dose response effects of 2-acetylaminofluorene on DNA damage, cytotoxicity, cell proliferation and neoplastic conversion in rat liver.
Cancer letters 1993;73(1):1-10.
1993: K Tokumo; T Umemura; H Sirma; Rolf Gebhardt; M C Poirier; Gary M Williams
Inhibition by gonadectomy of effects of 2-acetylaminofluorene in livers of male, but not female rats.
Carcinogenesis 1993;14(9):1747-50.
1993: Rolf Gebhardt
Multiple inhibitory effects of garlic extracts on cholesterol biosynthesis in hepatocytes.
Lipids 1993;28(7):613-9.
1993: J Fahrner; W T Labruyere; C Gaunitz; A F Moorman; Rolf Gebhardt; W H Lamers
Identification and functional characterization of regulatory elements of the glutamine synthetase gene from rat liver.
European journal of biochemistry / FEBS 1993;213(3):1067-73.
1992: Rolf Gebhardt
Cell-cell interactions: clues to hepatocyte heterogeneity and beyond?
Hepatology (Baltimore, Md.) 1992;16(3):843-5.
1992: H Wegner; Wolfgang Schareck; H Bayer-Helms; Rolf Gebhardt
Different proliferative potential of rat and pig hepatocytes in pure primary culture and coculture.
European journal of cell biology 1992;58(2):411-7.
1992: Rolf Gebhardt; U Marti
Heterogeneous distribution of the epidermal growth factor receptor in rat liver parenchyma.
Progress in histochemistry and cytochemistry 1992;26(1-4):164-8.
1992: Rolf Gebhardt
Metabolic zonation of the liver: regulation and implications for liver function.
Pharmacology & therapeutics 1992;53(3):275-354.
1991: Rolf Gebhardt; D Jonitza
Different proliferative responses of periportal and perivenous hepatocytes to EGF.
Biochemical and biophysical research communications 1991;181(3):1201-7.
1991: Rolf Gebhardt; K Lindros; W H Lamers; A F Moorman
Hepatocellular heterogeneity in ammonia metabolism: demonstration of limited colocalization of carbamoylphosphate synthetase and glutamine synthetase.
European journal of cell biology 1991;56(2):464-7.
1991: I Eisenmann-Tappe; S Wizigmann; Rolf Gebhardt
Glutamate uptake in primary cultures of biliary epithelial cells from normal rat liver.
Cell biology and toxicology 1991;7(4):315-25.
1991: Rolf Gebhardt
Inhibition of cholesterol biosynthesis by a water-soluble garlic extract in primary cultures of rat hepatocytes.
Arzneimittel-Forschung 1991;41(8):800-4.
1991: Ulrich Marti; Rolf Gebhardt
Acinar heterogeneity of the epidermal growth factor receptor in the liver of male rats.
European journal of cell biology 1991;55(1):158-64.
1991: Dieter Schrenk; I Eisenmann-Tappe; Rolf Gebhardt; D Mayer; M el Mouelhi; E Röhrdanz; Peter A Münzel; Karl Walter Bock
Drug metabolizing enzyme activities in rat liver epithelial cell lines, hepatocytes and bile duct cells.
Biochemical pharmacology 1991;41(11):1751-7.
1991: B Ugele; H J Kempen; J M Kempen; Rolf Gebhardt; P Meijer; Hans-Joerg burgerh; Hans M G Princen
Heterogeneity of rat liver parenchyma in cholesterol 7 alpha-hydroxylase and bile acid synthesis.
The Biochemical journal 1991;276 ( Pt 1)():73-7.
1991: Rolf Gebhardt
Histochemical approaches to the screening of carcinogens in vitro.
Progress in histochemistry and cytochemistry 1991;23(1-4):91-9.
1990: Rolf Gebhardt; H Fitzke; M Fausel; I Eisenmann-Tappe; Dieter Mecke
Influence of hormones and drugs on glutathione-S-transferase levels in primary culture of adult rat hepatocytes.
Cell biology and toxicology 1990;6(4):365-78.
1990: W Schrode; Dieter Mecke; Rolf Gebhardt
Induction of glutamine synthetase in periportal hepatocytes by cocultivation with a liver epithelial cell line.
European journal of cell biology 1990;53(1):35-41.
1990: Rolf Gebhardt
Altered acinar distribution of glutamine synthetase and different growth response of cultured enzyme-positive and -negative hepatocytes after partial hepatectomy.
Cancer research 1990;50(14):4407-10.
1990: Rolf Gebhardt
Heterogeneous intrahepatic distribution of glutamine synthetase.
Acta histochemica. Supplementband 1990;40():23-8.
1990: Ludger Schöls; Dieter Mecke; Rolf Gebhardt
Reestablishment of the heterogeneous distribution of hepatic glutamine synthetase during regeneration after CCl4-intoxication.
Histochemistry 1990;94(1):49-54.
1989: Rolf Gebhardt; T Tanaka; G M Williams
Glutamine synthetase heterogeneous expression as a marker for the cellular lineage of preneoplastic and neoplastic liver populations.
Carcinogenesis 1989;10(10):1917-23.
1989: W A Schulz; Rolf Gebhardt; D Mecke
Spermidine level and protein synthesis are coregulated in nonproliferating hepatocytes.
Biological chemistry Hoppe-Seyler 1989;370(7):729-36.
1989: Rolf Gebhardt; H Schmid; H Fitzke
Immunohistochemical localization of glutamine synthetase in human liver.
Experientia 1989;45(2):137-9.
1989: Rolf Gebhardt; R Jirtle; A F Moorman; W H Lamers; G Michalopoulos
Induction of glutamine synthetase and transient co-expression with carbamoylphosphate synthetase in hepatocytes transplanted into fat pads of syngeneic hosts.
Histochemistry 1989;92(4):337-42.
1989: Hans-Joerg burgerh; Rolf Gebhardt; C Mayer; Dieter Mecke
Different capacities for amino acid transport in periportal and perivenous hepatocytes isolated by digitonin/collagenase perfusion.
Hepatology (Baltimore, Md.) 1989;9(1):22-8.
1988: Rolf Gebhardt; A Ebert; G Bauer
Heterogeneous expression of glutamine synthetase mRNA in rat liver parenchyma revealed by in situ hybridization and Northern blot analysis of RNA from periportal and perivenous hepatocytes.
FEBS letters 1988;241(1-2):89-93.
1988: Rolf Gebhardt; I Schäfer-Degenhart
Monoclonal antibodies directed against rat liver epithelial cell lines selectively recognize bile duct epithelium in livers of adult rats.
Cell biology and toxicology 1988;4(4):379-92.
1988: Rolf Gebhardt; Hans-Joerg burgerh; H Heini; K L Schreiber; Dieter Mecke
Alterations of hepatic enzyme levels and of the acinar distribution of glutamine synthetase in response to experimental liver injury in the rat.
Hepatology (Baltimore, Md.) 1988;8(4):822-30.
1988: H Maruyama; T Tanaka; Rolf Gebhardt; L Berghem; Gary M Williams
Decreased fibronectin in rat liver altered foci and adenomas induced by N-2-fluorenylacetamide.
Laboratory investigation; a journal of technical methods and pathology 1988;58(6):630-5.
1988: Rolf Gebhardt
Different proliferative activity in vitro of periportal and perivenous hepatocytes.
Scandinavian journal of gastroenterology. Supplement 1988;151():8-18.
1987: Rolf Gebhardt; E Kleemann
Hormonal regulation of amino acid transport system N in primary cultures of rat hepatocytes.
European journal of biochemistry / FEBS 1987;166(2):339-44.
1987: Rolf Gebhardt; Hans-Joerg burgerh
Selective loss of hormonal induction of glutamate transport in primary cultures of hepatocytes from rats treated with CCl4.
Journal of hepatology 1987;4(3):381-9.
1987: Rolf Gebhardt; H Robenek
Ligand-dependent redistribution of the IgA receptor on cultured rat hepatocytes and its disturbance by cytochalasin B.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1987;35(3):301-9.
1987: H G Heini; Rolf Gebhardt; A Brecht; D Mecke
Purification and characterization of rat liver glutaminase.
European journal of biochemistry / FEBS 1987;162(3):541-6.
1987: J W Gaasbeek Janzen; Rolf Gebhardt; G H ten Voorde; Wouter H Lamers; R Charles; Antoon F M Moorman
Heterogeneous distribution of glutamine synthetase during rat liver development.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1987;35(1):49-54.
1986: Rolf Gebhardt; G M Williams
Amino acid transport in established adult rat liver epithelial cell lines.
Cell biology and toxicology 1986;2(1):9-20.
1986: S H Bigner; H S Friedman; J A Biegel; C J Wikstrand; J Mark; Rolf Gebhardt; L F Eng; D D Bigner
Specific chromosomal abnormalities characterize four established cell lines derived from malignant human gliomas.
Acta neuropathologica 1986;72(1):86-97.
1986: Rolf Gebhardt; J Cruise; K A Houck; N C Luetteke; A Novotny; F Thaler; G K Michalopoulos
Differential effect of growth factors on growth stimulation and phenotypic stability of glutamine-synthetase-positive and -negative hepatocytes in primary culture.
Differentiation; research in biological diversity 1986;33(1):45-55.
1985: W A Schulz; Rolf Gebhardt; D Mecke
Dexamethasone restores hormonal inducibility of ornithine decarboxylase in primary cultures of rat hepatocytes.
European journal of biochemistry / FEBS 1985;146(3):549-53.
1985: W Jung; Rolf Gebhardt; H Robenek
Primary culture of rat hepatocytes as a model system of canalicular development, biliary secretion, and intrahepatic cholestasis. V. Disturbance of the cellular membrane and bile canalicular ultrastructure induced by chlorpromazine.
Virchows Archiv. B, Cell pathology including molecular pathology 1985;49(4):349-63.
1984: Rolf Gebhardt
Participation of microtubules and microfilaments in the transcellular biliary secretion of immunoglobulin A in primary cultures of rat hepatocytes.
Experientia 1984;40(3):269-71.
1983: Rolf Gebhardt; D Mecke
Glutamate uptake by cultured rat hepatocytes is mediated by hormonally inducible, sodium-dependent transport systems.
FEBS letters 1983;161(2):275-8.
1983: H Robenek; Rolf Gebhardt
Primary cultures of rat hepatocytes as a model system of canalicular development, biliary secretion, and intrahepatic cholestasis. IV. Disintegration of bile canaliculi and disturbance of tight junction formation caused by vinblastine.
European journal of cell biology 1983;31(2):283-9.
1983: Rolf Gebhardt
Primary cultures of rat hepatocytes as a model system of canalicular development, biliary secretion, and intrahepatic cholestasis. III. Properties of the biliary transport of immunoglobulin A revealed by immunofluorescence.
Gastroenterology 1983;84(6):1462-70.
1983: Rolf Gebhardt
Disappearance of visible bile canaliculi caused by vinblastine in primary cultures of rat hepatocytes.
Experimental cell research 1983;144(1):218-23.
1983: Rolf Gebhardt; D Mecke
Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture.
The EMBO journal 1983;2(4):567-70.
1982: W Jung; Rolf Gebhardt; H Robenek
Primary cultures of rat hepatocytes as a model system of canalicular development, biliary secretion, and intrahepatic cholestasis. II. Taurolithocholate-induced alterations of canalicular morphology and of the distribution of filipin-cholesterol complexes.
European journal of cell biology 1982;29(1):77-82.
1982: Rolf Gebhardt; W Jung; H Robenek
Primary cultures of rat hepatocytes as a model system of canalicular development, biliary secretion, and intrahepatic cholestasis. I. Distribution of filipin-cholesterol complexes during de novo formation of bile canaliculi.
European journal of cell biology 1982;29(1):68-76.
1982: Rolf Gebhardt; W Jung
Biliary secretion of sodium fluorescein in primary monolayer cultures of adult rat hepatocytes and its stimulation by nicotinamide.
Journal of cell science 1982;56():233-44.
1982: W Jung; Rolf Gebhardt; D Mecke
Alterations in activity and ultrastructural localization of several phosphatases on the surface of adult rat hepatocytes in primary monolayer culture.
European journal of cell biology 1982;27(2):230-41.
1982: H Metzler; Rolf Gebhardt; W Oberrauch; D Mecke
A convenient and highly sensitive spectrophotometric assay for tryptophan 2,3-dioxygenase.
Analytical biochemistry 1982;121(1):10-6.
1982: H Robenek; W Jung; Rolf Gebhardt
The topography of filipin-cholesterol complexes in the plasma membrane of cultured hepatocytes and their relation to cell junction formation.
Journal of ultrastructure research 1982;78(1):95-106.
1979: Rolf Gebhardt; D Mecke
Perifused monolayer cultures of rat hepatocytes as an improved in vitro system for studies on ureogenesis.
Experimental cell research 1979;124(2):349-59.
1979: Rolf Gebhardt; D Mecke
The role of growth hormone, dexamethasone and triiodothyronine in the regulation of glutamine synthetase in primary cultures of rat hepatocytes.
European journal of biochemistry / FEBS 1979;100(2):519-25.
1979: Rolf Gebhardt; D Mecke
Permissive effect of dexamethasone on glucagon induction of urea-cycle enzymes in perifused primary monolayer cultures of rat hepatocytes.
European journal of biochemistry / FEBS 1979;97(1):29-35.
1978: Rolf Gebhardt; P Bellemann; D Mecke
Metabolic and enzymatic characteristics of adult rat liver parenchymal cells in non-proliferating primary monolayer cultures.
Experimental cell research 1978;112(2):431-41.
1977: P Bellemann; Rolf Gebhardt; D Mecke
An improved method for the isolation of hepatocytes from liver slices. Selective removal of Trypan blue-dyeable cells.
Analytical biochemistry 1977;81(2):408-15.