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Gernot Geginat

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Henriette Schneider; Horst Schroten; Matthias Dürken; Gernot Geginat; Michael Hogardt; Alexandra Kramer; Tobias Tenenbaum
Pseudomonas aeruginosa outbreak in a pediatric oncology care unit caused by an errant water jet into contaminated siphons.
Silke Grauling-Halama; Simone Schenk; Andreas Bubert; Gernot Geginat
Linkage of bacterial protein synthesis and presentation of MHC class I-restricted Listeria monocytogenes-derived antigenic peptides.
Stefan Weichert; Katrin Zahn; Annebärbel Dietz; Gernot Geginat; Anna Kristina Kilian; Konrad Reinshagen; Horst Schroten; Tobias Tenenbaum
Candidiasis caused by Candida kefyr in a neonate: case report.

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All Publications

2012: Henriette Schneider; Horst Schroten; Matthias Dürken; Gernot Geginat; Michael Hogardt; Alexandra Kramer; Tobias Tenenbaum
Pseudomonas aeruginosa outbreak in a pediatric oncology care unit caused by an errant water jet into contaminated siphons.
The Pediatric infectious disease journal 2012;31(6):648-50.
2012: Silke Grauling-Halama; Simone Schenk; Andreas Bubert; Gernot Geginat
Linkage of bacterial protein synthesis and presentation of MHC class I-restricted Listeria monocytogenes-derived antigenic peptides.
PloS one 2012;7(3):e33335.
2012: Stefan Weichert; Katrin Zahn; Annebärbel Dietz; Gernot Geginat; Anna Kristina Kilian; Konrad Reinshagen; Horst Schroten; Tobias Tenenbaum
Candidiasis caused by Candida kefyr in a neonate: case report.
BMC infectious diseases 2012;12():61.
2011: Silvia Boschi Bazan; Tanja Breinig; Gernot Geginat; Manfred J Schmitt; Frank Breinig
Uptake of various yeast genera by antigen-presenting cells and influence of subcellular antigen localization on the activation of ovalbumin-specific CD8 T lymphocytes.
Vaccine 2011;29(45):8165-73.
2011: Ina Tammer; Gernot Geginat; Dirk Schlüter
[Perioperative antimicrobial prophylaxis].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2011;46(10):674-82.
2011: Barbara Walch; Tanja Breinig; Gernot Geginat; Manfred J Schmitt; Frank Breinig
Yeast-based protein delivery to mammalian phagocytic cells is increased by coexpression of bacterial listeriolysin.
Microbes and infection / Institut Pasteur 2011;13(11):908-13.
2010: Holger Rüssmann; Klaus Panthel; Brigitte Köhn; Stefan Jellbauer; Sebastian E Winter; Sara Garbom; Hans Wolf-Watz; Sigrid Hoffmann; Silke Grauling-Halama; Gernot Geginat
Alternative endogenous protein processing via an autophagy-dependent pathway compensates for Yersinia-mediated inhibition of endosomal major histocompatibility complex class II antigen presentation.
Infection and immunity 2010;78(12):5138-50.
2010: Kristina Schauer; Gernot Geginat; Chunguang Liang; Werner Goebel; Thomas Dandekar; Thilo M Fuchs
Deciphering the intracellular metabolism of Listeria monocytogenes by mutant screening and modelling.
BMC genomics 2010;11():573.
2009: Silke Grauling-Halama; Udo Bahr; Simone Schenk; Gernot Geginat
Role of tripeptidyl peptidase II in the processing of Listeria monocytogenes-derived MHC class I-presented antigenic peptides.
Microbes and infection / Institut Pasteur 2009;11(8-9):795-802.
2009: Ralf Fleck; Wolfgang Kurz; Britta Quade; Gernot Geginat; Herbert Hof
Human dirofilariasis due to Dirofilaria repens mimicking a scrotal tumor.
Urology 2009;73(1):209.e1-3.
2008: Robert Leibiger; Katy Niedung; Gernot Geginat; Jürgen Heesemann; Konrad Trülzsch
Yersinia enterocolitica Yop mutants as oral live carrier vaccines.
Vaccine 2008;26(51):6664-70.
2008: Claudio Kupfahl; Anna Michalka; Cornelia Lass-Flörl; Guido Fischer; Gerhard Haase; Thomas Ruppert; Gernot Geginat; Herbert Hof
Gliotoxin production by clinical and environmental Aspergillus fumigatus strains.
International journal of medical microbiology : IJMM 2008;298(3-4):319-27.
2008: Rafaela Holtappels; Jozef Janda; Doris Thomas; Simone Schenk; Matthias J Reddehase; Gernot Geginat
Adoptive CD8 T cell control of pathogens cannot be improved by combining protective epitope specificities.
The Journal of infectious diseases 2008;197(4):622-9.
2008: Jozef Janda; Gernot Geginat
A deterministic model for the processing and presentation of bacteria-derived antigenic peptides.
Journal of theoretical biology 2008;250(3):532-46.
2007: Claudio Kupfahl; Thomas Ruppert; Annebärbel Dietz; Gernot Geginat; Holger Hof
Candida species fail to produce the immunosuppressive secondary metabolite gliotoxin in vitro.
FEMS yeast research 2007;7(6):986-92.
2006: Claudio Kupfahl; Gernot Geginat; Holger Hof
Gliotoxin-mediated suppression of innate and adaptive immune functions directed against Listeria monocytogenes.
Medical mycology : official publication of the International Society for Human and Animal Mycology 2006;44(7):591-9.
2006: Claudio Kupfahl; Thorsten Heinekamp; Gernot Geginat; Thomas Ruppert; Albert Härtl; Holger Hof; Axel A Brakhage
Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model.
Molecular microbiology 2006;62(1):292-302.
2006: Klaus Panthel; Katrin M Meinel; Victòria E Sevil Domènech; Gernot Geginat; Kathrin Linkemann; Dirk H Busch; Holger Rüssmann
Prophylactic anti-tumor immunity against a murine fibrosarcoma triggered by the Salmonella type III secretion system.
Microbes and infection / Institut Pasteur 2006;8(9-10):2539-46.
2006: Annette Paschen; Mingxia Song; Simone Schenk; Jozef Janda; Xuan Duc Nguyen; Wolfram Osen; Dirk Schadendorf; Gernot Geginat
Identification of a cross-reactive HLA-DRB1*0301-restricted CD4 T cell response directed against cholesterol-binding cytolysins from two different pathogens.
Microbes and infection / Institut Pasteur 2006;8(8):2034-43.
2006: Claudio Kupfahl; Gernot Geginat; Holger Hof
Lentinan has a stimulatory effect on innate and adaptive immunity against murine Listeria monocytogenes infection.
International immunopharmacology 2006;6(4):686-96.
2005: Christoph Schoen; Annette Kolb-Mäurer; Gernot Geginat; Daniela Löffler; Birgit Bergmann; Jochen Stritzker; Aladar A Szalay; Sabine Pilgrim; Werner Goebel
Bacterial delivery of functional messenger RNA to mammalian cells.
Cellular microbiology 2005;7(5):709-24.
2005: Konrad Trülzsch; Gernot Geginat; Thorsten Sporleder; Klaus Ruckdeschel; Reinhardt Hoffmann; Jürgen Heesemann; Holger Rüssmann
Yersinia outer protein P inhibits CD8 T cell priming in the mouse infection model.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):4244-51.
2004: Jozef Janda; Petra Schöneberger; mojca skoberne; Martin Messerle; Holger Rüssmann; Gernot Geginat
Cross-presentation of Listeria-derived CD8 T cell epitopes requires unstable bacterial translation products.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5644-51.
2004: Jochen Stritzker; Jozef Janda; Christoph Schoen; Marcus Taupp; Sabine Pilgrim; Ivaylo Gentschev; Peter Schreier; Gernot Geginat; Werner Goebel
Growth, virulence, and immunogenicity of Listeria monocytogenes aro mutants.
Infection and immunity 2004;72(10):5622-9.
2003: Sabine Pilgrim; Jochen Stritzker; Christoph Schoen; Annette Kolb-Mäurer; Gernot Geginat; M J Loessner; Ivaylo Gentschev; Werner Goebel
Bactofection of mammalian cells by Listeria monocytogenes: improvement and mechanism of DNA delivery.
Gene therapy 2003;10(24):2036-45.
2003: Holger Rüssmann; Ulrike Gerdemann; Emeka I Igwe; Klaus Panthel; Jürgen Heesemann; Sara Garbom; Hans Wolf-Watz; Gernot Geginat
Attenuated Yersinia pseudotuberculosis carrier vaccine for simultaneous antigen-specific CD4 and CD8 T-cell induction.
Infection and immunity 2003;71(6):3463-72.
2003: Christian Kamm; mojca skoberne; Gernot Geginat
CD8 T cell immunome analysis of Listeria monocytogenes.
FEMS immunology and medical microbiology 2003;35(3):235-42.
2002: Emeka I Igwe; Gernot Geginat; Holger Rüssmann
Concomitant cytosolic delivery of two immunodominant listerial antigens by Salmonella enterica serovar typhimurium confers superior protection against murine listeriosis.
Infection and immunity 2002;70(12):7114-9.
2002: mojca skoberne; Simone Schenk; Holger Hof; Gernot Geginat
Cross-presentation of Listeria monocytogenes-derived CD4 T cell epitopes.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1410-8.
2002: mojca skoberne; Gernot Geginat
Efficient in vivo presentation of Listeria monocytogenes- derived CD4 and CD8 T cell epitopes in the absence of IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1854-60.
2001: mojca skoberne; Rafaela Holtappels; Holger Hof; Gernot Geginat
Dynamic antigen presentation patterns of Listeria monocytogenes-derived CD8 T cell epitopes in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):2209-18.
2001: Marianne Kretschmar; Gernot Geginat; T Bertsch; S Walter; Holger Hof; Thomas Nichterlein
Influence of liposomal amphotericin B on CD8 T-cell function.
Antimicrobial agents and chemotherapy 2001;45(8):2383-5.
2001: Holger Rüssmann; Emeka I Igwe; J Sauer; Wolf-Dietrich Hardt; A Bubert; Gernot Geginat
Protection against murine listeriosis by oral vaccination with recombinant Salmonella expressing hybrid Yersinia type III proteins.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(1):357-65.
2001: Martina Deckert; Sabine Soltek; Gernot Geginat; Sonja Lütjen; Manuel Montesinos-Rongen; Holger Hof; Dirk Schlüter
Endogenous interleukin-10 is required for prevention of a hyperinflammatory intracerebral immune response in Listeria monocytogenes meningoencephalitis.
Infection and immunity 2001;69(7):4561-71.
2001: Gernot Geginat; Simone Schenk; mojca skoberne; W Goebel; Holger Hof
A novel approach of direct ex vivo epitope mapping identifies dominant and subdominant CD4 and CD8 T cell epitopes from Listeria monocytogenes.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1877-84.
2000: Hartmut Hengel; Uwe Reusch; Gernot Geginat; Rafaela Holtappels; Thomas Ruppert; E Hellebrand; Ulrich H Koszinowski
Macrophages escape inhibition of major histocompatibility complex class I-dependent antigen presentation by cytomegalovirus.
Journal of virology 2000;74(17):7861-8.
2000: Marianne Kretschmar; Andreas Hein; Gernot Geginat; C Mueller; Holger Hof; Thomas Nichterlein
Inefficient T cell memory in the brain of mice infected with Candida albicans.
Journal of neuroimmunology 2000;105(2):161-8.
2000: Holger Rüssmann; A Weissmüller; Gernot Geginat; Emeka I Igwe; Andreas Roggenkamp; A Bubert; W Goebel; H Hof; Jürgen Heesemann
Yersinia enterocolitica-mediated translocation of defined fusion proteins to the cytosol of mammalian cells results in peptide-specific MHC class I-restricted antigen presentation.
European journal of immunology 2000;30(5):1375-84.
2000: Rafaela Holtappels; Doris Thomas; Jürgen Podlech; Gernot Geginat; Hans-Peter Steffens; Matthias J Reddehase
The putative natural killer decoy early gene m04 (gp34) of murine cytomegalovirus encodes an antigenic peptide recognized by protective antiviral CD8 T cells.
Journal of virology 2000;74(4):1871-84.
1999: Gernot Geginat; Marianne Kretschmar; S Walter; D Junker; Holger Hof; Thomas Nichterlein
Suppression of acquired immunity against Listeria monocytogenes by amphotericin B-mediated inhibition of CD8 T cell function.
The Journal of infectious diseases 1999;180(4):1186-94.
1999: Gernot Geginat; Thomas Nichterlein; Marianne Kretschmar; Simone Schenk; Holger Hof; M Lalic-Mülthaler; W Goebel; A Bubert
Enhancement of the Listeria monocytogenes p60-specific CD4 and CD8 T cell memory by nonpathogenic Listeria innocua.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(8):4781-9.
1998: Rafaela Holtappels; Jürgen Podlech; Gernot Geginat; Hans-Peter Steffens; Doris Thomas; Matthias J Reddehase
Control of murine cytomegalovirus in the lungs: relative but not absolute immunodominance of the immediate-early 1 nonapeptide during the antiviral cytolytic T-lymphocyte response in pulmonary infiltrates.
Journal of virology 1998;72(9):7201-12.
1998: Gernot Geginat; M Lalic; Marianne Kretschmar; W Goebel; Holger Hof; D Palm; A Bubert
Th1 cells specific for a secreted protein of Listeria monocytogenes are protective in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(12):6046-55.
1997: Gernot Geginat; Thomas Ruppert; Hartmut Hengel; Rafaela Holtappels; Ulrich H Koszinowski
IFN-gamma is a prerequisite for optimal antigen processing of viral peptides in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3303-10.
1996: Thomas Nichterlein; Marianne Kretschmar; Gernot Geginat; K Hirth; H P Altenburg; Holger Hof
Effects of FK-506 on the course of murine salmonellosis.
Journal of chemotherapy (Florence, Italy) 1996;8(6):449-56.
1995: R Thäle; U Szepan; Hartmut Hengel; Gernot Geginat; Pero Lucin; Ulrich H Koszinowski
Identification of the mouse cytomegalovirus genomic region affecting major histocompatibility complex class I molecule transport.
Journal of virology 1995;69(10):6098-105.