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Todd Gehr

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Disorders

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Kidneys

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Justine M Abais; Krishna M Boini; Todd W B Gehr; Qinglian Liu; Min Xia; Chun Zhang; Pin-Lan Li
NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia.
S S Ghosh; R Krieg; H D Massey; D A Sica; Itaf Fakhry; S Ghosh; Todd W B Gehr
Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.
Amit Sharma; Todd L Teigeler; Martha Behnke; Adrian Cotterell; Robert Fisher; Todd W B Gehr; Anne King; Marc Posner
The mode of pretransplant dialysis does not affect postrenal transplant outcomes in african americans.

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2013: Justine M Abais; Krishna M Boini; Todd W B Gehr; Qinglian Liu; Min Xia; Chun Zhang; Pin-Lan Li
NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia.
Antioxidants & redox signaling 2013;18(13):1537-48.
2012: S S Ghosh; R Krieg; H D Massey; D A Sica; Itaf Fakhry; S Ghosh; Todd W B Gehr
Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.
American journal of physiology. Renal physiology 2012;302(4):F439-54.
2012: Amit Sharma; Todd L Teigeler; Martha Behnke; Adrian Cotterell; Robert Fisher; Todd W B Gehr; Anne King; Marc Posner
The mode of pretransplant dialysis does not affect postrenal transplant outcomes in african americans.
Journal of transplantation 2012;2012():303596.
2012: Avani D Joshi; Darcy Mays; Donald F Brophy; Spencer E Harpe; David A Holdford; Todd W B Gehr
Utilization Patterns of IV Iron and Erythropoiesis Stimulating Agents in Anemic Chronic Kidney Disease Patients: A Multihospital Study.
Anemia 2012;2012():248430.
2011: Mariano J Scian; J L Suh; A R Wolen; H Davis Massey; M U Mba; Marc Posner; Kellie J Archer; Adrian Cotterell; K G David; Todd W B Gehr; Anne L King; Daniel G Maluf; Valeria R Mas
MicroRNA profiles in allograft tissues and paired urines associate with chronic allograft dysfunction with IF/TA.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2011;11(10):2110-22.
2011: Mariano J Scian; Daniel G Maluf; Kellie J Archer; Jihee L Suh; Davis Massey; Ryan C Fassnacht; Benjamin Whitehill; Amit Sharma; Anne King; Todd W B Gehr; Adrian Cotterell; Marc P Posner; Valeria R Mas
Gene expression changes are associated with loss of kidney graft function and interstitial fibrosis and tubular atrophy: diagnosis versus prediction.
Transplantation 2011;91(6):657-65.
2011: Valeria R Mas; Thomas F Mueller; Marc P Posner; Qing Ren; Mariano J Scian; Jihee L Suh; Kellie J Archer; Krystle G David; Todd W B Gehr; Anne L King; Daniel G Maluf
Pretransplant transcriptome profiles identify among kidneys with delayed graft function those with poorer quality and outcome.
Molecular medicine (Cambridge, Mass.) 2011;17(11-12):1311-22.
2011: Don Farthing; Domenic Sica; Michael Hindle; Les Edinboro; Lei Xi; Todd W B Gehr; Lynne Gehr; Christine Farthing; Terri L Larus; Itaf Fakhry; H Thomas Karnes
A rapid and simple chemiluminescence method for screening levels of inosine and hypoxanthine in non-traumatic chest pain patients.
Luminescence : the journal of biological and chemical luminescence 2011;26(1):65-75.
2010: Christine Farthing; Don Farthing; Saisudha Koka; Terri Larus; Itaf Fakhry; Lei Xi; Rakesh C Kukreja; Domenic Sica; Todd W B Gehr
A simple and sensitive HPLC fluorescence method for determination of tadalafil in mouse plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(28):2891-5.
2010: Daniel E Carl; Catherine Grossman; Martha Behnke; Curtis N Sessler; Todd W B Gehr
Effect of timing of dialysis on mortality in critically ill, septic patients with acute renal failure.
Hemodialysis international. International Symposium on Home Hemodialysis 2010;14(1):11-7.
2009: Donald F Brophy; Bonny L Bukaveckas; Andrea Ferreira-Gonzalez; Kellie J Archer; Erika J Martin; Todd W B Gehr
A pilot study of genetic polymorphisms and hemodialysis vascular access thrombosis.
Hemodialysis international. International Symposium on Home Hemodialysis 2009;13(1):19-26.
2008: Lena M Maynor; Daniel E Carl; Gary R Matzke; Todd W B Gehr; Christine Farthing; Don Farthing; Donald F Brophy
An in vivo-in vitro study of cefepime and cefazolin dialytic clearance during high-flux hemodialysis.
Pharmacotherapy 2008;28(8):977-83.
2008: Shreyank S Tripathi; Eric M Gibney; Todd W B Gehr; Anne L King; Matthew J Beckman
High prevalence of vitamin D deficiency in African American kidney transplant recipients.
Transplantation 2008;85(5):767-70.
2007: Don Farthing; Lynne Gehr; H Thomas Karnes; Domenic A Sica; Todd W B Gehr; Terri Larus; Christine Farthing; Lei Xi
Effects of salicylic acid on post-ischaemic ventricular function and purine efflux in isolated mouse hearts.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2007;12(6):623-34.
2007: Domenic A Sica; Todd W B Gehr; William H Frishman
Use of diuretics in the treatment of heart failure in the elderly.
Heart failure clinics 2007;3(4):455-64.
2007: Don Farthing; Domenic A Sica; Todd W B Gehr; Bill Wilson; Itaf Fakhry; Terri Larus; Christine Farthing; H Thomas Karnes
An HPLC method for determination of inosine and hypoxanthine in human plasma from healthy volunteers and patients presenting with potential acute cardiac ischemia.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;854(1-2):158-64.
2007: Domenic A Sica; Todd W B Gehr; William H Frishman
Use of diuretics in the treatment of heart failure in the elderly.
Clinics in geriatric medicine 2007;23(1):107-21.
2006: Donald F Brophy; Marcus E Carr; Erika J Martin; Jürgen Venitz; Todd W B Gehr
The pharmacokinetics of enoxaparin do not correlate with its pharmacodynamic effect in patients receiving dialysis therapies.
Journal of clinical pharmacology 2006;46(8):887-94.
2006: Donald F Brophy; Erika J Martin; Todd W B Gehr; Al M Best; K Paul; Marcus E Carr
Thrombin generation time is a novel parameter for monitoring enoxaparin therapy in patients with end-stage renal disease.
Journal of thrombosis and haemostasis : JTH 2006;4(2):372-6.
2006: Domenic A Sica; Todd W B Gehr
Desmopressin : safety considerations in patients with chronic renal disease.
Drug safety : an international journal of medical toxicology and drug experience 2006;29(7):553-6.
2005: Don Farthing; Domenic A Sica; Itaf Fakhry; Terri Larus; Sid Ghosh; Christine Farthing; Michael Vranian; Todd W B Gehr
Simple HPLC-UV method for determination of iohexol, iothalamate, p-aminohippuric acid and n-acetyl-p-aminohippuric acid in human plasma and urine with ERPF, GFR and ERPF/GFR ratio determination using colorimetric analysis.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;826(1-2):267-72.
2005: Domenic A Sica; Todd W B Gehr; Siddhartha Ghosh
Clinical pharmacokinetics of losartan.
Clinical pharmacokinetics 2005;44(8):797-814.
2004: Donald F Brophy; Erika J Martin; Al M Best; Todd W B Gehr; Marcus E Carr
Antifactor Xa activity correlates to thrombin generation time, platelet contractile force and clot elastic modulus following ex vivo enoxaparin exposure in patients with and without renal dysfunction.
Journal of thrombosis and haemostasis : JTH 2004;2(8):1299-304.
2004: Donald F Brophy; Erika J Martin; Todd W B Gehr; Marcus E Carr
Enhanced anticoagulant activity of enoxaparin in patients with ESRD as measured by thrombin generation time.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2004;44(2):270-7.
2004: Niall McLaughlin; Todd W B Gehr; Domenic A Sica
Aldosterone-receptor antagonism and end-stage renal disease.
Current hypertension reports 2004;6(4):327-30.
2004: Don Farthing; Terri Larus; Itaf Fakhry; Todd W B Gehr; Jayne Prats; Domenic A Sica
Liquid chromatography method for determination of bivalirudin in human plasma and urine using automated ortho-phthalaldehyde derivatization and fluorescence detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;802(2):355-9.
2003: Domenic A Sica; Todd W B Gehr
Diuretic use in stage 5 chronic kidney disease and end-stage renal disease.
Current opinion in nephrology and hypertension 2003;12(5):483-90.
2003: Domenic A Sica; Todd W B Gehr; Clyde Yancy
Hyperkalemia, congestive heart failure, and aldosterone receptor antagonism.
Congestive heart failure (Greenwich, Conn.) 2003;9(4):224-9.
2003: Siddhartha S Ghosh; Todd W B Gehr; Shobha Ghosh; Itaf Fakhry; Domenic A Sica; Vijay Lyall; Anton C Schoolwerth
PPARgamma ligand attenuates PDGF-induced mesangial cell proliferation: role of MAP kinase.
Kidney international 2003;64(1):52-62.
2003: Domenic A Sica; Todd W B Gehr
Calcium-channel blockers and end-stage renal disease: pharmacokinetic and pharmacodynamic considerations.
Current opinion in nephrology and hypertension 2003;12(2):123-31.
2003: Todd W B Gehr; Filitsa Bender; Jeffrey C Fink; Paul Light; Karen Elliott; Christie Shield; Mary Turner; Cathy Mays; Joan Parrish; Nancy Armistead
Improving adequacy of peritoneal dialysis in ESRD Network 5 (Maryland; Washington, DC; Virginia; West Virginia).
Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 2003;19():86-92.
2002: Domenic A Sica; Todd W B Gehr
The pharmacokinetics and pharmacodynamics of angiotensin-receptor blockers in end-stage renal disease.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2002;3(4):247-54.
2002: Siddhartha Ghosh; Domenic A Sica; Anton C Schoolwerth; Richard J Quigg; Mark Haas; Itaf Fakhry; Todd W B Gehr
The role of the renin-angiotensin system in cholesterol and puromycin mediated renal injury.
The American journal of the medical sciences 2002;324(6):296-304.
2002: Domenic A Sica; Todd W B Gehr
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and rhabdomyolysis: considerations in the renal failure patient.
Current opinion in nephrology and hypertension 2002;11(2):123-33.
2002: Adrian Cotterell; Robert A Fisher; Anne L King; Todd W B Gehr; Sherfield Sherfield Dawson; Richard K Sterling; R Todd Stravitz; Velimir A Luketic; Arun J Sanyal; Mitchell L Shiffman; Marc P Posner
Calcineurin inhibitor-induced chronic nephrotoxicity in liver transplant patients is reversible using rapamycin as the primary immunosuppressive agent.
Clinical transplantation 2002;16 Suppl 7():49-51.
2002: Domenic A Sica; Todd W B Gehr
Rhabdomyolysis and statin therapy: relevance to the elderly.
The American journal of geriatric cardiology 2002;11(1):48-55.
2001: Jerome I Tokars; Todd W B Gehr; William R Jarvis; JOHN ANDERSON; Nancy Armistead; ER Miller; Joan Parrish; S Qaiyumi; Matthew Arduino; SC Holt; Fred C Tenover; Glennis Westbrook; Paul Light
Vancomycin-resistant enterococci colonization in patients at seven hemodialysis centers.
Kidney international 2001;60(4):1511-6.
2001: Jerome I Tokars; Paul Light; JOHN ANDERSON; ER Miller; Joan Parrish; Nancy Armistead; William R Jarvis; Todd W B Gehr
A prospective study of vascular access infections at seven outpatient hemodialysis centers.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2001;37(6):1232-40.
2001: Domenic A Sica; Todd W B Gehr
Direct vasodilators and their role in hypertension management: minoxidil.
Journal of clinical hypertension (Greenwich, Conn.) 2001;3(2):110-4.
2001: Donald F Brophy; LD Wazny; Todd W B Gehr; T J Comstock; Jürgen Venitz
The pharmacokinetics of subcutaneous enoxaparin in end-stage renal disease.
Pharmacotherapy 2001;21(2):169-74.
2000: Domenic A Sica; W Liao; Todd W B Gehr; S Khan; Mohammed Jemal; CL Delaney; I M Ferreira; B K Malhotra
Disposition and safety of omapatrilat in subjects with renal impairment.
Clinical pharmacology and therapeutics 2000;68(3):261-9.
2000: Donald F Brophy; J F Wallace; Daniel T Kennedy; Todd W B Gehr; David A Holdford
Cost-effectiveness of sevelamer versus calcium carbonate plus atorvastatin to reduce LDL in patients with chronic renal insufficiency with dyslipidemia and hyperphosphatemia.
Pharmacotherapy 2000;20(8):950-7.
2000: GL Bloomfield; Harvey J Sugerman; Charles R Blocher; Todd W B Gehr; Domenic A Sica
Chronically increased intra-abdominal pressure produces systemic hypertension in dogs.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24(7):819-24.
2000: Domenic A Sica; C E Halstenson; Todd W B Gehr; W F Keane
Pharmacokinetics and blood pressure response of losartan in end-stage renal disease.
Clinical pharmacokinetics 2000;38(6):519-26.
2000: Domenic A Sica; Todd W B Gehr; A Fernandez
Risk-benefit ratio of angiotensin antagonists versus ACE inhibitors in end-stage renal disease.
Drug safety : an international journal of medical toxicology and drug experience 2000;22(5):350-60.
2000: James M Doty; Bob H Saggi; Charles R Blocher; Itaf Fakhry; Todd W B Gehr; Domenic A Sica; Harvey J Sugerman
Effects of increased renal parenchymal pressure on renal function.
The Journal of trauma 2000;48(5):874-7.
2000: A A Pedro; Todd W B Gehr; Donald F Brophy; Domenic A Sica
The pharmacokinetics and pharmacodynamics of losartan in continuous ambulatory peritoneal dialysis.
Journal of clinical pharmacology 2000;40(4):389-95.
1999: James M Doty; Bob H Saggi; Harvey J Sugerman; Charles R Blocher; R Pin; Itaf Fakhry; Todd W B Gehr; Domenic A Sica
Effect of increased renal venous pressure on renal function.
The Journal of trauma 1999;47(6):1000-3.
1999: Todd W B Gehr; David M Tenero; Duane A Boyle; Y Qian; Domenic A Sica; N H Shusterman
The pharmacokinetics of carvedilol and its metabolites after single and multiple dose oral administration in patients with hypertension and renal insufficiency.
European journal of clinical pharmacology 1999;55(4):269-77.
1997: Don Farthing; Domenic A Sica; Itaf Fakhry; A Pedro; Todd W B Gehr
Simple high-performance liquid chromatographic method for determination of losartan and E-3174 metabolite in human plasma, urine and dialysate.
Journal of chromatography. B, Biomedical sciences and applications 1997;704(1-2):374-8.
1997: Domenic A Sica; Maria R Marino; Janis L Hammett; I Ferreira; Todd W B Gehr; Neville F Ford
The pharmacokinetics of irbesartan in renal failure and maintenance hemodialysis.
Clinical pharmacology and therapeutics 1997;62(6):610-8.
1997: Todd W B Gehr; Domenic A Sica; PH Slugg; Janis L Hammett; R Raymond; Neville F Ford
The pharmacokinetics of pravastatin in patients on chronic hemodialysis.
European journal of clinical pharmacology 1997;53(2):117-21.
1996: Domenic A Sica; Todd W B Gehr
Diuretic combinations in refractory oedema states: pharmacokinetic-pharmacodynamic relationships.
Clinical pharmacokinetics 1996;30(3):229-49.
1996: D C Gore; J M Dalton; Todd W B Gehr
Colloid infusions reduce glomerular filtration in resuscitated burn victims.
The Journal of trauma 1996;40(3):356-60.
1996: J Shi; E Ripley; Todd W B Gehr; Domenic A Sica; K A Dandekar; P H Hinderling
Pharmacokinetics of sematilide in renal failure.
Journal of clinical pharmacology 1996;36(2):131-43.
1995: Domenic A Sica; M W Lo; W C Shaw; W F Keane; Todd W B Gehr; C E Halstenson; K Lipschutz; C I Furtek; M A Ritter; S Shahinfar
The pharmacokinetics of losartan in renal insufficiency.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1995;13(1):S49-52.
1994: DW Rudy; Todd W B Gehr; G R Matzke; W G Kramer; Domenic A Sica; D Craig Brater
The pharmacodynamics of intravenous and oral torsemide in patients with chronic renal insufficiency.
Clinical pharmacology and therapeutics 1994;56(1):39-47.
1994: Todd W B Gehr; DW Rudy; G R Matzke; W G Kramer; Domenic A Sica; D Craig Brater
The pharmacokinetics of intravenous and oral torsemide in patients with chronic renal insufficiency.
Clinical pharmacology and therapeutics 1994;56(1):31-8.
1994: Don Farthing; Domenic A Sica; Itaf Fakhry; Todd W B Gehr
Novel high-performance liquid chromatographic method using solid-phase on-line elution for determination of metolazone in plasma and whole blood.
Journal of chromatography. B, Biomedical applications 1994;653(2):171-6.
1994: E B Ripley; Todd W B Gehr; H Wallace; J Wade; C Kish; Domenic A Sica
The effect of nonsteroidal agents (NSAIDs) on the pharmacokinetics and pharmacodynamics of metolazone.
International journal of clinical pharmacology and therapeutics 1994;32(1):12-8.
1994: Todd W B Gehr; B A Walters
Catheter-related Mycobacterium chelonei infection in a CAPD patient.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 1994;14(3):278-9.
1994: E B Ripley; Todd W B Gehr; C W Kish; Domenic A Sica
Hormonal, blood pressure, and peritoneal transport response to short-term ACE inhibition.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 1994;14(4):378-83.
1993: J D Hanna; J W Foreman; Todd W B Gehr; James C M Chan; J Wolfrum; J Ruddley
The peritoneal equilibration test in children.
Pediatric nephrology (Berlin, Germany) 1993;7(6):731-4.
1993: D Craig Brater; D R Rudy; J R Voelker; P K Greene; Todd W B Gehr; Domenic A Sica
Pharmacokinetics and pharmacodynamics of torasemide in patients with chronic renal insufficiency--preliminary evaluation.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1993;7 Suppl 1():69-73.
1993: Todd W B Gehr; Domenic A Sica; D M Grasela; K L Duchin
The pharmacokinetics and pharmacodynamics of fosinopril in haemodialysis patients.
European journal of clinical pharmacology 1993;45(5):431-6.
1992: Don Farthing; T Karnes; Todd W B Gehr; C March; Itaf Fakhry; Domenic A Sica
External-standard high-performance liquid chromatographic method for quantitative determination of furosemide in plasma by using solid-phase extraction and on-line elution.
Journal of pharmaceutical sciences 1992;81(6):569-71.
1991: Todd W B Gehr; Domenic A Sica; D C Brater; H J Wallace; J Davis; Itaf Fakhry
Metolazone pharmacokinetics and pharmacodynamics in renal transplantation.
International journal of clinical pharmacology, therapy, and toxicology 1991;29(3):116-23.
1991: Todd W B Gehr; Domenic A Sica; D M Grasela; Itaf Fakhry; J Davis; K L Duchin
Fosinopril pharmacokinetics and pharmacodynamics in chronic ambulatory peritoneal dialysis patients.
European journal of clinical pharmacology 1991;41(2):165-9.
1990: Don Farthing; Itaf Fakhry; Todd W B Gehr; Domenic A Sica
Quantitation of metolazone in urine by high-performance liquid chromatography with fluorescence detection.
Journal of chromatography 1990;534():228-32.
1989: Domenic A Sica; Todd W B Gehr
Diuretics in congestive heart failure.
Cardiology clinics 1989;7(1):87-97.
1989: Domenic A Sica; Todd W B Gehr
Triamterene and the kidney.
Nephron 1989;51(4):454-61.
1988: Todd W B Gehr; Domenic A Sica; C Brater; J Davis; Itaf Fakhry
Furosemide pharmacokinetics and pharmacodynamics in renal transplantation.
Clinical pharmacology and therapeutics 1988;43(5):547-53.
1987: Todd W B Gehr; Domenic A Sica
Case report and review of the literature: ureteral endometriosis.
The American journal of the medical sciences 1987;294(5):346-52.