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Lee Gehrke

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Dina Uzri; Lee Gehrke
Nucleotide sequences and modifications that determine RIG-I/RNA binding and signaling activities.
Vienna L Reichert; Mehee Choi; Jessica E Petrillo; Lee Gehrke
Alfalfa mosaic virus coat protein bridges RNA and RNA-dependent RNA polymerase in vitro.
Michael Boyce; Felicia Scott; Laura M Guogas; Lee Gehrke
Base-pairing potential identified by in vitro selection predicts the kinked RNA backbone observed in the crystal structure of the alfalfa mosaic virus RNA-coat protein complex.

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All Publications

2009: Dina Uzri; Lee Gehrke
Nucleotide sequences and modifications that determine RIG-I/RNA binding and signaling activities.
Journal of virology 2009;83(9):4174-84.
2007: Vienna L Reichert; Mehee Choi; Jessica E Petrillo; Lee Gehrke
Alfalfa mosaic virus coat protein bridges RNA and RNA-dependent RNA polymerase in vitro.
Virology 2007;364(1):214-26.
2006: Michael Boyce; Felicia Scott; Laura M Guogas; Lee Gehrke
Base-pairing potential identified by in vitro selection predicts the kinked RNA backbone observed in the crystal structure of the alfalfa mosaic virus RNA-coat protein complex.
Journal of molecular recognition : JMR 2006;19(1):68-78.
2005: Laura M Guogas; Siana M Laforest; Lee Gehrke
Coat protein activation of alfalfa mosaic virus replication is concentration dependent.
Journal of virology 2005;79(9):5752-61.
2005: Jessica E Petrillo; Gail Rocheleau; Brenna Kelley-Clarke; Lee Gehrke
Evaluation of the conformational switch model for alfalfa mosaic virus RNA replication.
Journal of virology 2005;79(9):5743-51.
2004: Laura M Guogas; David J Filman; James M Hogle; Lee Gehrke
Cofolding organizes alfalfa mosaic virus RNA and coat protein for replication.
Science (New York, N.Y.) 2004;306(5704):2108-11.
2004: Gail Rocheleau; Jessica E Petrillo; Laura M Guogas; Lee Gehrke
Degenerate in vitro genetic selection reveals mutations that diminish alfalfa mosaic virus RNA replication without affecting coat protein binding.
Journal of virology 2004;78(15):8036-46.
2004: Siana M Laforest; Lee Gehrke
Spatial determinants of the alfalfa mosaic virus coat protein binding site.
RNA (New York, N.Y.) 2004;10(1):48-58.
1998: P Ansel-McKinney; Lee Gehrke
RNA determinants of a specific RNA-coat protein peptide interaction in alfalfa mosaic virus: conservation of homologous features in ilarvirus RNAs.
Journal of molecular biology 1998;278(4):767-85.
1998: M M Swanson; P Ansel-McKinney; F Houser-Scott; V Yusibov; LS Loesch-Fries; Lee Gehrke
Viral coat protein peptides with limited sequence homology bind similar domains of alfalfa mosaic virus and tobacco streak virus RNAs.
Journal of virology 1998;72(4):3227-34.
1997: K J MacBeth; Young Tae Ro; Lee Gehrke; Jean L Patterson
Cleavage site mapping and substrate-specificity of Leishmaniavirus 2-1 capsid endoribonuclease activity.
Journal of biochemistry 1997;122(1):193-200.
1997: L E Hann; A C Webb; J M Cai; Lee Gehrke
Identification of a competitive translation determinant in the 3' untranslated region of alfalfa mosaic virus coat protein mRNA.
Molecular and cellular biology 1997;17(4):2005-13.
1997: F Houser-Scott; P Ansel-McKinney; J M Cai; Lee Gehrke
In vitro genetic selection analysis of alfalfa mosaic virus coat protein binding to 3'-terminal AUGC repeats in the viral RNAs.
Journal of virology 1997;71(3):2310-9.
1996: P Ansel-McKinney; Simon W Scott; M Swanson; X Ge; Lee Gehrke
A plant viral coat protein RNA binding consensus sequence contains a crucial arginine.
The EMBO journal 1996;15(18):5077-84.
1996: D Rousseau; R Kaspar; Igor B Rosenwald; Lee Gehrke; Nahum Sonenberg
Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(3):1065-70.
1995: Igor B Rosenwald; R Kaspar; D Rousseau; Lee Gehrke; Philippe Leboulch; J J Chen; Emmett V Schmidt; Nahum Sonenberg; I M London
Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels.
The Journal of biological chemistry 1995;270(36):21176-80.
1995: L E Hann; Lee Gehrke
mRNAs containing the unstructured 5' leader sequence of alfalfa mosaic virus RNA 4 translate inefficiently in lysates from poliovirus-infected HeLa cells.
Journal of virology 1995;69(8):4986-93.
1994: P J Chefalo; J M Yang; K V Ramaiah; Lee Gehrke; J J Chen
Inhibition of protein synthesis in insect cells by baculovirus-expressed heme-regulated eIF-2 alpha kinase.
The Journal of biological chemistry 1994;269(41):25788-94.
1994: F Houser-Scott; M L Baer; K F Liem; J M Cai; Lee Gehrke
Nucleotide sequence and structural determinants of specific binding of coat protein or coat protein peptides to the 3' untranslated region of alfalfa mosaic virus RNA 4.
Journal of virology 1994;68(4):2194-205.
1994: M L Baer; F Houser; LS Loesch-Fries; Lee Gehrke
Specific RNA binding by amino-terminal peptides of alfalfa mosaic virus coat protein.
The EMBO journal 1994;13(3):727-35.
1992: Philip E. auron; G J Quigley; L J Rosenwasser; Lee Gehrke
Multiple amino acid substitutions suggest a structural basis for the separation of biological activity and receptor binding in a mutant interleukin-1 beta protein.
Biochemistry 1992;31(29):6632-8.
1991: A C Webb; M K Bradley; S A Phelan; J Q Wu; Lee Gehrke
Use of the polymerase chain reaction for screening and evaluation of recombinant baculovirus clones.
BioTechniques 1991;11(4):512-9.
1991: J J Chen; M S Throop; Lee Gehrke; I Kuo; J K Pal; Michael H Brodsky; I M London
Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7729-33.
1991: J J Chen; J K Pal; RA Petryshyn; I Kuo; J M Yang; M S Throop; Lee Gehrke; I M London
Amino acid microsequencing of internal tryptic peptides of heme-regulated eukaryotic initiation factor 2 alpha subunit kinase: homology to protein kinases.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(2):315-9.
1990: Lee Gehrke; Steve Jobling; L S Paik; B McDonald; L J Rosenwasser; Philip E. auron
A point mutation uncouples human interleukin-1 beta biological activity and receptor binding.
The Journal of biological chemistry 1990;265(11):5922-5.
1988: Steve Jobling; Philip E. auron; G Gurka; A C Webb; B McDonald; L J Rosenwasser; Lee Gehrke
Biological activity and receptor binding of human prointerleukin-1 beta and subpeptides.
The Journal of biological chemistry 1988;263(31):16372-8.
1988: Karen S Browning; S R Lax; J Humphreys; J M Ravel; Steve Jobling; Lee Gehrke
Evidence that the 5'-untranslated leader of mRNA affects the requirement for wheat germ initiation factors 4A, 4F, and 4G.
The Journal of biological chemistry 1988;263(20):9630-4.
1988: Steve Jobling; C M Cuthbert; S G Rogers; R T Fraley; Lee Gehrke
In vitro transcription and translational efficiency of chimeric SP6 messenger RNAs devoid of 5' vector nucleotides.
Nucleic acids research 1988;16(10):4483-98.
1987: Steve Jobling; Lee Gehrke
Enhanced translation of chimaeric messenger RNAs containing a plant viral untranslated leader sequence.
Nature 1987;325(6105):622-5.
1986: L J Rosenwasser; A C Webb; B D Clark; S Irie; L Chang; C A Dinarello; Lee Gehrke; S M Wolff; A Rich; Philip E. auron
Expression of biologically active human interleukin 1 subpeptides by transfected simian COS cells.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(14):5243-6.
1984: G J Quigley; Lee Gehrke; D A Roth; Philip E. auron
Computer-aided nucleic acid secondary structure modeling incorporating enzymatic digestion data.
Nucleic acids research 1984;12(1 Pt 1):347-66.
1983: Lee Gehrke; Philip E. auron; G J Quigley; A Rich; N Sonenberg
5'-Conformation of capped alfalfa mosaic virus ribonucleic acid 4 may reflect its independence of the cap structure or of cap-binding protein for efficient translation.
Biochemistry 1983;22(22):5157-64.