Teunis Geijtenbeek

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Gringhuis Sonja I; den Dunnen Jeroen; Litjens Manja; van der Vlist Michiel; Geijtenbeek Teunis B H
Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori.
Op den Brouw Marjoleine L; Binda Rekha S; Geijtenbeek Teunis B H; Janssen Harry L A; Woltman Andrea M
The mannose receptor acts as hepatitis B virus surface antigen receptor mediating interaction with intrahepatic dendritic cells.
Geijtenbeek Teunis B H; den Dunnen Jeroen; Gringhuis Sonja I
Pathogen recognition by DC-SIGN shapes adaptive immunity.

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All Publications

2009: Gringhuis Sonja I; den Dunnen Jeroen; Litjens Manja; van der Vlist Michiel; Geijtenbeek Teunis B H
Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori.
Nature immunology 2009;10(10):1081-8.
2009: Op den Brouw Marjoleine L; Binda Rekha S; Geijtenbeek Teunis B H; Janssen Harry L A; Woltman Andrea M
The mannose receptor acts as hepatitis B virus surface antigen receptor mediating interaction with intrahepatic dendritic cells.
Virology 2009;393(1):84-90.
2009: Geijtenbeek Teunis B H; den Dunnen Jeroen; Gringhuis Sonja I
Pathogen recognition by DC-SIGN shapes adaptive immunity.
Future microbiology 2009;4():879-90.
2009: Geijtenbeek Teunis B H; Gringhuis Sonja I
Signalling through C-type lectin receptors: shaping immune responses.
Nature reviews. Immunology 2009;9(7):465-79.
2009: Saeland Eirikur; de Jong Marein A W P; Nabatov Alexey A; Kalay Hakan; Geijtenbeek Teunis B H; van Kooyk Yvette
MUC1 in human milk blocks transmission of human immunodeficiency virus from dendritic cells to T cells.
Molecular immunology 2009;46(11-12):2309-16.
2009: den Dunnen Jeroen; Gringhuis Sonja I; Geijtenbeek Teunis B H
Innate signaling by the C-type lectin DC-SIGN dictates immune responses.
Cancer immunology, immunotherapy : CII 2009;58(7):1149-57.
2009: Gringhuis Sonja I; den Dunnen Jeroen; Litjens Manja; van der Vlist Michiel; Wevers Brigitte; Bruijns Sven C M; Geijtenbeek Teunis B H
Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-kappaB activation through Raf-1 and Syk.
Nature immunology 2009;10(2):203-13.
2009: de Witte Lot; de Jong Marein A W P; den Dunnen Jeroen; van Kooyk Yvette; Geijtenbeek Teunis B H
Identification of pathogen receptors on dendritic cells to understand their function and to identify new drug targets.
Methods in molecular biology (Clifton, N.J.) 2009;531():267-85.
2008: de Jong Marein A W P; de Witte Lot; Bolmstedt Anders; van Kooyk Yvette; Geijtenbeek Teunis B H
Dendritic cells mediate herpes simplex virus infection and transmission through the C-type lectin DC-SIGN.
The Journal of general virology 2008;89(Pt 10):2398-409.
2008: de Jong Marein A W P; de Witte Lot; Oudhoff Menno J; Gringhuis Sonja I; Gallay Philippe; Geijtenbeek Teunis B H
TNF-alpha and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivo.
The Journal of clinical investigation 2008;118(10):3440-52.
2008: Cunningham Anthony L; Carbone Francis; Geijtenbeek Teunis B H
Langerhans cells and viral immunity.
European journal of immunology 2008;38(9):2377-85.
2008: van Vliet Sandra J; Paessens Lutz C; Broks-van den Berg Venice C M; Geijtenbeek Teunis B H; van Kooyk Yvette
The C-type lectin macrophage galactose-type lectin impedes migration of immature APCs.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):3148-55.
2008: Nabatov Alexey A; de Jong Marein A W P; de Witte Lot; Bulgheresi Silvia; Geijtenbeek Teunis B H
C-type lectin Mermaid inhibits dendritic cell mediated HIV-1 transmission to CD4+ T cells.
Virology 2008;378(2):323-8.
2008: Op den Brouw M L; de Jong M A W P; Ludwig I S; van der Molen R G; Janssen H L A; Geijtenbeek T B H; Woltman A M
Branched oligosaccharide structures on HBV prevent interaction with both DC-SIGN and L-SIGN.
Journal of viral hepatitis 2008;15(9):675-83.
2008: Koppel Estella A; Litjens Manja; van den Berg Venice C; van Kooyk Yvette; Geijtenbeek Teunis B H
Interaction of SIGNR1 expressed by marginal zone macrophages with marginal zone B cells is essential to early IgM responses against Streptococcus pneumoniae.
Molecular immunology 2008;45(10):2881-7.
2008: de Witte Lot; de Vries Rory D; van der Vlist Michiel; Yüksel Selma; Litjens Manja; de Swart Rik L; Geijtenbeek Teunis B H
DC-SIGN and CD150 have distinct roles in transmission of measles virus from dendritic cells to T-lymphocytes.
PLoS pathogens 2008;4(4):e1000049.
2008: Bobardt Michael D; Cheng Guofeng; de Witte Lot; Selvarajah Suganya; Chatterji Udayan; Sanders-Beer Brigitte E; Geijtenbeek Teunis B H; Chisari Francis V; Gallay Philippe A
Hepatitis C virus NS5A anchor peptide disrupts human immunodeficiency virus.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(14):5525-30.
2008: García-Vallejo Juan J; van Liempt Ellis; da Costa Martins Paula; Beckers Cora; van het Hof Bert; Gringhuis Sonja I; Zwaginga Jaap-Jan; van Dijk Willem; Geijtenbeek Teunis B H; van Kooyk Yvette; van Die Irma
DC-SIGN mediates adhesion and rolling of dendritic cells on primary human umbilical vein endothelial cells through LewisY antigen expressed on ICAM-2.
Molecular immunology 2008;45(8):2359-69.
2008: Appelmelk B J; den Dunnen J; Driessen N N; Ummels R; Pak M; Nigou J; Larrouy-Maumus G; Gurcha S S; Movahedzadeh F; Geurtsen J; Brown E J; Eysink Smeets M M; Besra G S; Willemsen P T J; Lowary T L; van Kooyk Y; Maaskant J J; Stoker N G; van der Ley P; Puzo G; Vandenbroucke-Grauls C M J E; Wieland C W; van der Poll T; Geijtenbeek T B H; van der Sar A M; Bitter W
The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction.
Cellular microbiology 2008;10(4):930-44.
2008: Hovius Joppe W R; de Jong Marein A W P; den Dunnen Jeroen; Litjens Manja; Fikrig Erol; van der Poll Tom; Gringhuis Sonja I; Geijtenbeek Teunis B H
Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization.
PLoS pathogens 2008;4(2):e31.
2008: de Witte Lot; Nabatov Alexey; Geijtenbeek Teunis B H
Distinct roles for DC-SIGN+-dendritic cells and Langerhans cells in HIV-1 transmission.
Trends in molecular medicine 2008;14(1):12-9.
2007: de Witte Lot; Bobardt Michael; Chatterji Udayan; Degeest Gisèle; David Guido; Geijtenbeek Teunis B H; Gallay Philippe
Syndecan-3 is a dendritic cell-specific attachment receptor for HIV-1.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19464-9.
2007: de Swart Rik L; Ludlow Martin; de Witte Lot; Yanagi Yusuke; van Amerongen Geert; McQuaid Stephen; Yüksel Selma; Geijtenbeek Teunis B H; Duprex W Paul; Osterhaus Albert D M E
Predominant infection of CD150+ lymphocytes and dendritic cells during measles virus infection of macaques.
PLoS pathogens 2007;3(11):e178.
2007: van Vliet Sandra J; den Dunnen Jeroen; Gringhuis Sonja I; Geijtenbeek Teunis Bh; van Kooyk Yvette
Innate signaling and regulation of Dendritic cell immunity.
Current opinion in immunology 2007;19(4):435-40.
2007: van Vliet Sandra J; Aarnoudse Corlien A; Broks-van den Berg Venice C M; Boks Martine; Geijtenbeek Teunis B H; van Kooyk Yvette
MGL-mediated internalization and antigen presentation by dendritic cells: a role for tyrosine-5.
European journal of immunology 2007;37(8):2075-81.
2007: Saeland Eirikur; van Vliet Sandra J; Bäckström Malin; van den Berg Venice C M; Geijtenbeek Teunis B H; Meijer Gerrit A; van Kooyk Yvette
The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma.
Cancer immunology, immunotherapy : CII 2007;56(8):1225-36.
2007: Dasgupta Suryasarathi; Navarrete Ana-Maria; Bayry Jagadeesh; Delignat Sandrine; Wootla Bharath; André Sébastien; Christophe Olivier; Nascimbeni Michelina; Jacquemin Marc; Martinez-Pomares Luisa; Geijtenbeek Teunis B H; Moris Arnaud; Saint-Remy Jean-Marie; Kazatchkine Michel D; Kaveri Srinivas V; Lacroix-Desmazes Sébastien
A role for exposed mannosylations in presentation of human therapeutic self-proteins to CD4+ T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):8965-70.
2007: Gringhuis Sonja I; den Dunnen Jeroen; Litjens Manja; van Het Hof Bert; van Kooyk Yvette; Geijtenbeek Teunis B H
C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB.
Immunity 2007;26(5):605-16.
2007: de Witte Lot; Nabatov Alexey; Pion Marjorie; Fluitsma Donna; de Jong Marein A W P; de Gruijl Tanja; Piguet Vincent; van Kooyk Yvette; Geijtenbeek Teunis B H
Langerin is a natural barrier to HIV-1 transmission by Langerhans cells.
Nature medicine 2007;13(3):367-71.
2007: van Montfort Thijs; Nabatov Alexey A; Geijtenbeek Teunis B H; Pollakis Georgios; Paxton William A
Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):3177-85.
2007: Wieland Catharina W; Koppel Estella A; den Dunnen Jeroen; Florquin Sandrine; McKenzie Andrew N J; van Kooyk Yvette; van der Poll Tom; Geijtenbeek Teunis B H
Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis.
Microbes and infection / Institut Pasteur 2007;9(2):134-41.
2007: de Witte Lot; Zoughlami Younes; Aengeneyndt Birgit; David Guido; van Kooyk Yvette; Gissmann Lutz; Geijtenbeek Teunis B H
Binding of human papilloma virus L1 virus-like particles to dendritic cells is mediated through heparan sulfates and induces immune activation.
Immunobiology 2007;212(9-10):679-91.
2006: Nabatov Alexey A; van Montfort Thijs; Geijtenbeek Teunis B H; Pollakis Georgios; Paxton William A
Interaction of HIV-1 with dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-expressing cells is influenced by gp120 envelope modifications associated with disease progression.
The FEBS journal 2006;273(21):4944-58.
2006: van Vliet Sandra J; Gringhuis Sonja I; Geijtenbeek Teunis B H; van Kooyk Yvette
Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45.
Nature immunology 2006;7(11):1200-8.
2006: van Kooyk Yvette; Geijtenbeek Teunis B H
Toll-like receptors keep antigen sorting on the right track.
Immunity 2006;25(4):525-7.
2006: Naarding Marloes A; Dirac Annette M; Ludwig Irene S; Speijer Dave; Lindquist Susanne; Vestman Eva-Lotta; Stax Martijn J; Geijtenbeek Teunis B H; Pollakis Georgios; Hernell Olle; Paxton William A
Bile salt-stimulated lipase from human milk binds DC-SIGN and inhibits human immunodeficiency virus type 1 transfer to CD4+ T cells.
Antimicrobial agents and chemotherapy 2006;50(10):3367-74.
2006: Ludwig Irene S; Geijtenbeek Teunis B H; van Kooyk Yvette
Two way communication between neutrophils and dendritic cells.
Current opinion in pharmacology 2006;6(4):408-13.
2006: Lekkerkerker Annemarie N; van Kooyk Yvette; Geijtenbeek Teunis B H
Viral piracy: HIV-1 targets dendritic cells for transmission.
Current HIV research 2006;4(2):169-76.
2006: de Witte Lot; Abt Marion; Schneider-Schaulies Sibylle; van Kooyk Yvette; Geijtenbeek Teunis B H
Measles virus targets DC-SIGN to enhance dendritic cell infection.
Journal of virology 2006;80(7):3477-86.
2006: Oosterling Steven J; Mels Anneke K; Geijtenbeek Teunis B H; van der Bij Gerben J; Tuk Cornelis W; Vuylsteke Ronald J C L M; van Leeuwen Paul A M; Meijer Gerrit A; Meijer Sybren; Beelen Robert H J; van Egmond Marjolein
Preoperative granulocyte/macrophage colony-stimulating factor (GM-CSF) increases hepatic dendritic cell numbers and clustering with lymphocytes in colorectal cancer patients.
Immunobiology 2006;211(6-8):641-9.
2006: van Vliet Sandra J; van Liempt Ellis; Geijtenbeek Teunis B H; van Kooyk Yvette
Differential regulation of C-type lectin expression on tolerogenic dendritic cell subsets.
Immunobiology 2006;211(6-8):577-85.
2005: van Gisbergen Klaas P J M; Geijtenbeek Teunis B H; van Kooyk Yvette
Close encounters of neutrophils and DCs.
Trends in immunology 2005;26(12):626-31.
2005: van Gisbergen Klaas P J M; Ludwig Irene S; Geijtenbeek Teunis B H; van Kooyk Yvette
Interactions of DC-SIGN with Mac-1 and CEACAM1 regulate contact between dendritic cells and neutrophils.
FEBS letters 2005;579(27):6159-68.
2005: Naarding Marloes A; Ludwig Irene S; Groot Fedde; Berkhout Ben; Geijtenbeek Teunis B H; Pollakis Georgios; Paxton William A
Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes.
The Journal of clinical investigation 2005;115(11):3256-64.
2005: Koppel Estella A; Wieland Catharina W; van den Berg Venice C M; Litjens Manja; Florquin Sandrine; van Kooyk Yvette; van der Poll Tom; Geijtenbeek Teunis B H
Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection.
European journal of immunology 2005;35(10):2962-9.
2005: van Gisbergen Klaas P J M; Aarnoudse Corlien A; Meijer Gerrit A; Geijtenbeek Teunis B H; van Kooyk Yvette
Dendritic cells recognize tumor-specific glycosylation of carcinoembryonic antigen on colorectal cancer cells through dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin.
Cancer research 2005;65(13):5935-44.
2005: van Vliet Sandra J; van Liempt Ellis; Saeland Eirikur; Aarnoudse Corlien A; Appelmelk Ben; Irimura Tatsuro; Geijtenbeek Teunis B H; Blixt Ola; Alvarez Richard; van Die Irma; van Kooyk Yvette
Carbohydrate profiling reveals a distinctive role for the C-type lectin MGL in the recognition of helminth parasites and tumor antigens by dendritic cells.
International immunology 2005;17(5):661-9.
2005: van Gisbergen Klaas P J M; Sanchez-Hernandez Marta; Geijtenbeek Teunis B H; van Kooyk Yvette
Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN.
The Journal of experimental medicine 2005;201(8):1281-92.
2005: van Gisbergen Klaas P J M; Paessens Lutz C; Geijtenbeek Teunis B H; van Kooyk Yvette
Molecular mechanisms that set the stage for DC-T cell engagement.
Immunology letters 2005;97(2):199-208.
2005: Groot Fedde; Geijtenbeek Teunis B H; Sanders Rogier W; Baldwin Christopher E; Sanchez-Hernandez Marta; Floris René; van Kooyk Yvette; de Jong Esther C; Berkhout Ben
Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction.
Journal of virology 2005;79(5):3009-15.
2005: Koppel Estella A; van Gisbergen Klaas P J M; Geijtenbeek Teunis B H; van Kooyk Yvette
Distinct functions of DC-SIGN and its homologues L-SIGN (DC-SIGNR) and mSIGNR1 in pathogen recognition and immune regulation.
Cellular microbiology 2005;7(2):157-65.
2005: Koppel Estella A; Saeland Eirikur; de Cooker Désirée J M; van Kooyk Yvette; Geijtenbeek Teunis B H
DC-SIGN specifically recognizes Streptococcus pneumoniae serotypes 3 and 14.
Immunobiology 2005;210(2-4):203-10.
2005: Koppel Estella A; Ludwig Irene S; Appelmelk Ben J; van Kooyk Yvette; Geijtenbeek Teunis B H
Carbohydrate specificities of the murine DC-SIGN homologue mSIGNR1.
Immunobiology 2005;210(2-4):195-201.
2004: Arrighi Jean-François; Pion Marjorie; Garcia Eduardo; Escola Jean-Michel; van Kooyk Yvette; Geijtenbeek Teunis B; Piguet Vincent
DC-SIGN-mediated infectious synapse formation enhances X4 HIV-1 transmission from dendritic cells to T cells.
The Journal of experimental medicine 2004;200(10):1279-88.
2004: Lekkerkerker Annemarie N; Ludwig Irene S; van Vliet Sandra J; van Kooyk Yvette; Geijtenbeek Teunis B H
Potency of HIV-1 envelope glycoprotein gp120 antibodies to inhibit the interaction of DC-SIGN with HIV-1 gp120.
Virology 2004;329(2):465-76.
2004: Arrighi Jean-François; Pion Marjorie; Wiznerowicz Maciej; Geijtenbeek Teunis B; Garcia Eduardo; Abraham Shahnaz; Leuba Florence; Dutoit Valérie; Ducrey-Rundquist Odile; van Kooyk Yvette; Trono Didier; Piguet Vincent
Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells.
Journal of virology 2004;78(20):10848-55.
2004: Lekkerkerker Annemarie N; Van Kooyk Yvette; Geijtenbeek Teunis B H
Mucosal-targeted AIDS vaccines: the next generation?
Trends in microbiology 2004;12(10):447-50.
2004: Ludwig Irene S; Lekkerkerker Annemarie N; Depla Erik; Bosman Fons; Musters René J P; Depraetere Stany; van Kooyk Yvette; Geijtenbeek Teunis B H
Hepatitis C virus targets DC-SIGN and L-SIGN to escape lysosomal degradation.
Journal of virology 2004;78(15):8322-32.
2004: van Kooyk Yvette; Engering Anneke; Lekkerkerker Annemarie N; Ludwig Irene S; Geijtenbeek Teunis B H
Pathogens use carbohydrates to escape immunity induced by dendritic cells.
Current opinion in immunology 2004;16(4):488-93.
2004: Van Liempt Ellis; Imberty Anne; Bank Christine M C; Van Vliet Sandra J; Van Kooyk Yvette; Geijtenbeek Teunis B H; Van Die Irma
Molecular basis of the differences in binding properties of the highly related C-type lectins DC-SIGN and L-SIGN to Lewis X trisaccharide and Schistosoma mansoni egg antigens.
The Journal of biological chemistry 2004;279(32):33161-7.
2004: Engering Anneke; van Vliet Sandra J; Hebeda Konnie; Jackson David G; Prevo Remko; Singh Satwinder K; Geijtenbeek Teunis B H; van Krieken Han; van Kooyk Yvette
Dynamic populations of dendritic cell-specific ICAM-3 grabbing nonintegrin-positive immature dendritic cells and liver/lymph node-specific ICAM-3 grabbing nonintegrin-positive endothelial cells in the outer zones of the paracortex of human lymph nodes.
The American journal of pathology 2004;164(5):1587-95.
2004: Koppel Estella A; Ludwig Irene S; Hernandez Marta Sanchez; Lowary Todd L; Gadikota Rajendrakumar R; Tuzikov Alexander B; Vandenbroucke-Grauls Christina M J E; van Kooyk Yvette; Appelmelk Ben J; Geijtenbeek Teunis B H
Identification of the mycobacterial carbohydrate structure that binds the C-type lectins DC-SIGN, L-SIGN and SIGNR1.
Immunobiology 2004;209(1-2):117-27.
2004: Geijtenbeek Teunis B H; van Vliet Sandra J; Engering Anneke; 't Hart Bert A; van Kooyk Yvette
Self- and nonself-recognition by C-type lectins on dendritic cells.
Annual review of immunology 2004;22():33-54.
2003: Stuyt Rogier J L; Netea Mihai G; Geijtenbeek Teunis B H; Kullberg Bart Jan; Dinarello Charles A; van der Meer Jos W M
Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes.
Immunology 2003;110(3):329-34.
2003: van Kooyk Yvette; Geijtenbeek Teunis B H
DC-SIGN: escape mechanism for pathogens.
Nature reviews. Immunology 2003;3(9):697-709.
2003: Geijtenbeek Teunis B H; van Kooyk Yvette
Pathogens target DC-SIGN to influence their fate DC-SIGN functions as a pathogen receptor with broad specificity.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2003;111(7-8):698-714.
2003: van Die Irma; van Vliet Sandra J; Nyame A Kwame; Cummings Richard D; Bank Christine M C; Appelmelk Ben; Geijtenbeek Teunis B H; van Kooyk Yvette
The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.
Glycobiology 2003;13(6):471-8.
2003: van Kooyk Yvette; Appelmelk Ben; Geijtenbeek Teunis B H
A fatal attraction: Mycobacterium tuberculosis and HIV-1 target DC-SIGN to escape immune surveillance.
Trends in molecular medicine 2003;9(4):153-9.
2003: Kämmerer Ulrike; Eggert Andreas O; Kapp Michaela; McLellan Alexander D; Geijtenbeek Teunis B H; Dietl Johannes; van Kooyk Yvette; Kämpgen Eckhart
Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy.
The American journal of pathology 2003;162(3):887-96.
2003: Appelmelk Ben J; van Die Irma; van Vliet Sandra J; Vandenbroucke-Grauls Christina M J E; Geijtenbeek Teunis B H; van Kooyk Yvette
Cutting edge: carbohydrate profiling identifies new pathogens that interact with dendritic cell-specific ICAM-3-grabbing nonintegrin on dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(4):1635-9.
2003: Geijtenbeek Teunis B H; Van Vliet Sandra J; Koppel Estella A; Sanchez-Hernandez Marta; Vandenbroucke-Grauls Christine M J E; Appelmelk Ben; Van Kooyk Yvette
Mycobacteria target DC-SIGN to suppress dendritic cell function.
The Journal of experimental medicine 2003;197(1):7-17.
2003: Geijtenbeek T B H; van Kooyk Y
DC-SIGN: a novel HIV receptor on DCs that mediates HIV-1 transmission.
Current topics in microbiology and immunology 2003;276():31-54.
2002: Geijtenbeek Teunis B H; Groot Peter C; Nolte Martijn A; van Vliet Sandra J; Gangaram-Panday Shanti T; van Duijnhoven Gerard C F; Kraal Georg; van Oosterhout Antoon J M; van Kooyk Yvette
Marginal zone macrophages express a murine homologue of DC-SIGN that captures blood-borne antigens in vivo.
Blood 2002;100(8):2908-16.
2002: Engering Anneke; Geijtenbeek Teunis B H; van Kooyk Yvette
Immune escape through C-type lectins on dendritic cells.
Trends in immunology 2002;23(10):480-5.
2002: Engering Anneke; Van Vliet Sandra J; Geijtenbeek Teunis B H; Van Kooyk Yvette
Subset of DC-SIGN(+) dendritic cells in human blood transmits HIV-1 to T lymphocytes.
Blood 2002;100(5):1780-6.
2002: van Kooyk Yvette; Geijtenbeek Teunis B H
A novel adhesion pathway that regulates dendritic cell trafficking and T cell interactions.
Immunological reviews 2002;186():47-56.
2002: Geijtenbeek Teunis B H; Engering Anneke; Van Kooyk Yvette
DC-SIGN, a C-type lectin on dendritic cells that unveils many aspects of dendritic cell biology.
Journal of leukocyte biology 2002;71(6):921-31.
2002: Engering Anneke; Geijtenbeek Teunis B H; van Vliet Sandra J; Wijers Mietske; van Liempt Ellis; Demaurex Nicolas; Lanzavecchia Antonio; Fransen Jack; Figdor Carl G; Piguet Vincent; van Kooyk Yvette
The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(5):2118-26.
2002: Geijtenbeek Teunis B H; van Duijnhoven Gerard C F; van Vliet Sandra J; Krieger Elmar; Vriend Gert; Figdor Carl G; van Kooyk Yvette
Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1.
The Journal of biological chemistry 2002;277(13):11314-20.
2002: Smits Hermelijn H; de Jong Esther C; Schuitemaker Joost H N; Geijtenbeek Theo B H; van Kooyk Yvette; Kapsenberg Martien L; Wierenga Eddy A
Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(4):1710-6.
2001: Geijtenbeek T B; Koopman G; van Duijnhoven G C; van Vliet S J; van Schijndel A C; Engering A; Heeney J L; van Kooyk Y
Rhesus macaque and chimpanzee DC-SIGN act as HIV/SIV gp120 trans-receptors, similar to human DC-SIGN.
Immunology letters 2001;79(1-2):101-7.
2001: Bleijs D A; Geijtenbeek T B; Figdor C G; van Kooyk Y
DC-SIGN and LFA-1: a battle for ligand.
Trends in immunology 2001;22(8):457-63.
2001: Geijtenbeek T B; van Vliet S J; van Duijnhoven G C; Figdor C G; van Kooyk Y
DC-SIGN, a dentritic cell-specific HIV-1 receptor present in placenta that infects T cells in trans-a review.
Placenta 2001;22 Suppl A():S19-23.
2001: Bashirova A A; Geijtenbeek T B; van Duijnhoven G C; van Vliet S J; Eilering J B; Martin M P; Wu L; Martin T D; Viebig N; Knolle P A; KewalRamani V N; van Kooyk Y; Carrington M
A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection.
The Journal of experimental medicine 2001;193(6):671-8.
2000: Geijtenbeek T B; Krooshoop D J; Bleijs D A; van Vliet S J; van Duijnhoven G C; Grabovsky V; Alon R; Figdor C G; van Kooyk Y
DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking.
Nature immunology 2000;1(4):353-7.
2000: Geijtenbeek T B; Kwon D S; Torensma R; van Vliet S J; van Duijnhoven G C; Middel J; Cornelissen I L; Nottet H S; KewalRamani V N; Littman D R; Figdor C G; van Kooyk Y
DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells.
Cell 2000;100(5):587-97.
2000: Geijtenbeek T B; Torensma R; van Vliet S J; van Duijnhoven G C; Adema G J; van Kooyk Y; Figdor C G
Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses.
Cell 2000;100(5):575-85.
1999: Geijtenbeek T B; van Kooyk Y; van Vliet S J; Renes M H; Raymakers R A; Figdor C G
High frequency of adhesion defects in B-lineage acute lymphoblastic leukemia.
Blood 1999;94(2):754-64.

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