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Carsten Geisler

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Beatrice Dyring-Andersen; Carsten Geisler; Jens Peter H Lauritsen; Marianne B Løvendorf; Michael Bzorek; Sally Dabelsteen; Lone Skov; Knud Søndergaard; Charlotte Menné Bonefeld
CD4(+) T cells producing interleukin (IL)-17, IL-22 and interferon-γ are major effector T cells in nickel allergy.
Ida Holst Pedersen; Claudia Vetter-Kauczok; Mariusz A Wasik; Andreas Willerslev-Olsen; Anders Woetmann; Qian Zhang; Jurgen C Becker; Charlotte Menné Bonefeld; Sally Dabelsteen; Carsten Geisler; Katharina Luise Kopp; Thorbjørn Krejsgaard; Britt Lauenborg; Niels Odum
Vascular endothelial growth factor receptor-3 expression in mycosis fungoides.
Marie T Vennegaard; Anders Woetmann; Nannie Bangsgaard; Charlotte Menné Bonefeld; Carsten Geisler; Peter H Hagedorn; Marianne B Løvendorf; Niels Odum; Lone Skov
Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice.

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2013: Beatrice Dyring-Andersen; Carsten Geisler; Jens Peter H Lauritsen; Marianne B Løvendorf; Michael Bzorek; Sally Dabelsteen; Lone Skov; Knud Søndergaard; Charlotte Menné Bonefeld
CD4(+) T cells producing interleukin (IL)-17, IL-22 and interferon-γ are major effector T cells in nickel allergy.
Contact dermatitis 2013;68(6):339-47.
2013: Ida Holst Pedersen; Claudia Vetter-Kauczok; Mariusz A Wasik; Andreas Willerslev-Olsen; Anders Woetmann; Qian Zhang; Jurgen C Becker; Charlotte Menné Bonefeld; Sally Dabelsteen; Carsten Geisler; Katharina Luise Kopp; Thorbjørn Krejsgaard; Britt Lauenborg; Niels Odum
Vascular endothelial growth factor receptor-3 expression in mycosis fungoides.
Leukemia & lymphoma 2013;54(4):819-26.
2012: Marie T Vennegaard; Anders Woetmann; Nannie Bangsgaard; Charlotte Menné Bonefeld; Carsten Geisler; Peter H Hagedorn; Marianne B Løvendorf; Niels Odum; Lone Skov
Allergic contact dermatitis induces upregulation of identical microRNAs in humans and mice.
Contact dermatitis 2012;67(5):298-305.
2012: Thorbjørn Krejsgaard; Niels Odum; Mariusz A Wasik; Carsten Geisler; Anders Woetmann
Regulatory T cells and immunodeficiency in mycosis fungoides and Sézary syndrome.
Leukemia 2012;26(3):424-32.
2012: Marina Rode von Essen; Martin Kongsbak; Carsten Geisler
Mechanisms behind functional avidity maturation in T cells.
Clinical & developmental immunology 2012;2012():163453.
2012: Trine Bøegh Levring; Bodil L Nielsen; Niels Odum; Marina Rode von Essen; Anders Woetmann; Charlotte Menné Bonefeld; Ann Kathrine Hansen; Martin Kongsbak; Carsten Geisler
Activated human CD4+ T cells express transporters for both cysteine and cystine.
Scientific reports 2012;2():266.
2011: Ulrik Ralfkiaer; Mads A Røpke; Lone Skov; Rolf Søkilde; Malgorzata Sokolowska-Wojdylo; Lars Svensson; Marie T Vennegaard; Mariusz A Wasik; Anders Woetmann; John R Zibert; Catherine Queille-Roussel; Elisabeth Ralfkiaer; Charlotte B Ahler; Nannie Bangsgaard; Charlotte Menné Bonefeld; Carsten Geisler; Lise Mette Gjerdrum; Christian Glue; Robert Gniadecki; Kirsten Grønbaek; Peter H Hagedorn; Katharina L Kopp; Thorbjørn Krejsgaard; tord labuda; Britt Lauenborg; Thomas Litman; Marianne B Løvendorf; Anne-Merete Mathiesen; Niels Odum
Diagnostic microRNA profiling in cutaneous T-cell lymphoma (CTCL).
Blood 2011;118(22):5891-900.
2011: Mikkel L Hansen; Katharina L M Kopp; Thorbjørn Krejsgaard; Thomas Litman; Niels Odum; Rolf Søkilde; Per thor Straten; Mariusz A Wasik; Anders Woetmann; Carsten Geisler; Karsten W Eriksen
IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity.
Molecular immunology 2011;48(15-16):2087-93.
2011: Ann K Hansen; Martin Kongsbak; Arno Müllbacher; Matthias Regner; Lasse Boding; Charlotte Menné Bonefeld; Carsten Geisler; Niels Odum; Marina R von Essen
TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections.
European journal of immunology 2011;41(7):1948-57.
2011: Thorbjørn Krejsgaard; Ulrik Ralfkiaer; Erik Clasen-Linde; Karsten Wessel Eriksen; Katharina L Kopp; Charlotte Menné Bonefeld; Carsten Geisler; Sally Dabelsteen; Mariusz A Wasik; Elisabeth Ralfkiaer; Anders Woetmann; Niels Odum
Malignant cutaneous T-cell lymphoma cells express IL-17 utilizing the Jak3/Stat3 signaling pathway.
The Journal of investigative dermatology 2011;131(6):1331-8.
2010: Thorbjørn Krejsgaard; Katharina Kopp; Elisabeth Ralfkiaer; Ayelah E Willumsgaard; Karsten Wessel Eriksen; tord labuda; Susanne Rasmussen; Anne-Merete Mathiesen; Carsten Geisler; Britt Lauenborg; Jürgen C Becker; Qian Zhang; Mariusz A Wasik; Niels Odum; Anders Woetmann
A novel xenograft model of cutaneous T-cell lymphoma.
Experimental dermatology 2010;19(12):1096-102.
2010: I M C Rubin; S Dabelsteen; M M Nielsen; I R White; Jeanne Duus Johansen; Carsten Geisler; Charlotte Menné Bonefeld
Repeated exposure to hair dye induces regulatory T cells in mice.
The British journal of dermatology 2010;163(5):992-8.
2010: Britt Lauenborg; Katharina Kopp; Thorbjørn Krejsgaard; Karsten W Eriksen; Carsten Geisler; Sally Dabelsteen; Robert Gniadecki; Qian Zhang; Mariusz A Wasik; Anders Woetmann; Niels Odum
Programmed cell death-10 enhances proliferation and protects malignant T cells from apoptosis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2010;118(10):719-28.
2010: Lasse Boding; Martin Weiss Nielsen; Charlotte Menné Bonefeld; Marina Rode von Essen; Bodil L Nielsen; Jens Peter H Lauritsen; Ann Kathrine Hansen; Martin M Nielsen; Martin Kongsbak; Maria Rubin; Marie Torp Vennegaard; Niels Odum; Carsten Geisler
Polymorphisms of the T cell receptor CD3delta and CD3epsilon chains affect anti-CD3 antibody binding and T cell activation.
Molecular immunology 2010;47(15):2450-7.
2010: K L M Kopp; C S Kauczok; B Lauenborg; Thorbjørn Krejsgaard; Karsten Wessel Eriksen; Qian Zhang; Mariusz A Wasik; Carsten Geisler; Elisabeth Ralfkiaer; Jürgen C Becker; N Ødum; Anders Woetmann
COX-2-dependent PGE(2) acts as a growth factor in mycosis fungoides (MF).
Leukemia 2010;24(6):1179-85.
2010: Karsten Wessel Eriksen; Anders Woetmann; Lone Skov; Thorbjørn Krejsgaard; Lone F Bovin; Mikkel L Hansen; Kirsten Grønbaek; Nils Billestrup; Mogens H Nissen; Carsten Geisler; Mariusz A Wasik; Niels Ødum
Deficient SOCS3 and SHP-1 expression in psoriatic T cells.
The Journal of investigative dermatology 2010;130(6):1590-7.
2010: Marina Rode von Essen; Martin Kongsbak; Peter Schjerling; Klaus Olgaard; Niels Odum; Carsten Geisler
Vitamin D controls T cell antigen receptor signaling and activation of human T cells.
Nature immunology 2010;11(4):344-9.
2010: Charlotte Menné Bonefeld; J M Larsen; Sally Dabelsteen; Carsten Geisler; I R White; Torkil Menné; Jeanne Duus Johansen
Consumer available permanent hair dye products cause major allergic immune activation in an animal model.
The British journal of dermatology 2010;162(1):102-7.
2009: Lasse Boding; Charlotte Menné Bonefeld; Bodil L Nielsen; Jens Peter H Lauritsen; Marina Rode von Essen; Ann Kathrine Hansen; Jeppe Madura Larsen; Martin M Nielsen; Niels Odum; Carsten Geisler
TCR down-regulation controls T cell homeostasis.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(8):4994-5005.
2009: Thorbjørn Krejsgaard; Claudia S Vetter-Kauczok; Anders Woetmann; Hermann Kneitz; Karsten Wessel Eriksen; Paola Lovato; Qian Zhang; Mariusz A Wasik; Carsten Geisler; Elisabeth Ralfkiaer; Jürgen C Becker; Niels Ødum
Ectopic expression of B-lymphoid kinase in cutaneous T-cell lymphoma.
Blood 2009;113(23):5896-904.
2009: Jeppe Madura Larsen; Charlotte Menné Bonefeld; Steen Seier Poulsen; Carsten Geisler; Lone Skov
IL-23 and T(H)17-mediated inflammation in human allergic contact dermatitis.
The Journal of allergy and clinical immunology 2009;123(2):486-92.
2009: Karsten W Eriksen; Henrik Søndergaard; Anders Woetmann; Thorbjørn Krejsgaard; Kresten Skak; Carsten Geisler; Mariusz A Wasik; Niels Odum
The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy.
Molecular immunology 2009;46(5):812-20.
2008: Charlotte Menné Bonefeld; Mariëlle Haks; Bodil Nielsen; Marina von Essen; Lasse Boding; Ann Kathrine Hansen; Jeppe Madura Larsen; Niels Odum; Paul Krimpenfort; Ada Kruisbeek; Jan Pravsgaard Christensen; Allan Randrup Thomsen; Carsten Geisler
TCR down-regulation controls virus-specific CD8+ T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(11):7786-99.
2008: Carsten Geisler; Arne Kolstad; Anna Laurell; Niels S Andersen; Lone B Pedersen; Mats Jerkeman; Mikael Eriksson; Marie Nordström; Eva Kimby; Anne Marie Boesen; Outi Kuittinen; Grete F Lauritzsen; Herman Nilsson-Ehle; Elisabeth Ralfkiaer; Måns Akerman; Mats Ehinger; Christer Sundström; Ruth Langholm; Jan Delabie; Marja-Liisa Karjalainen-Lindsberg; Peter Brown; Erkki Elonen
Long-term progression-free survival of mantle cell lymphoma after intensive front-line immunochemotherapy with in vivo-purged stem cell rescue: a nonrandomized phase 2 multicenter study by the Nordic Lymphoma Group.
Blood 2008;112(7):2687-93.
2007: Jeppe Madura Larsen; Carsten Geisler; Martin Weiss Nielsen; Lasse Boding; Marina von Essen; Ann Kathrine Hansen; Lone Skov; Charlotte Menné Bonefeld
Cellular dynamics in the draining lymph nodes during sensitization and elicitation phases of contact hypersensitivity.
Contact dermatitis 2007;57(5):300-8.
2007: Anders Woetmann; Paola Lovato; Karsten Wessel Eriksen; Thorbjørn Krejsgaard; tord labuda; Qian Zhang; Anne-Merethe Mathiesen; Carsten Geisler; Arne Svejgaard; Mariusz A Wasik; Niels Ødum
Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins.
Blood 2007;109(8):3325-32.
2006: Marina von Essen; Martin Weiss Nielsen; Charlotte Menné Bonefeld; Lasse Boding; Jeppe M Larsen; Michael Leitges; Gottfried Baier; Niels Odum; Carsten Geisler
Protein kinase C (PKC) alpha and PKC theta are the major PKC isotypes involved in TCR down-regulation.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7502-10.
2005: Karsten Wessel Eriksen; Paola Lovato; Lone Skov; Thorbjørn Krejsgaard; Keld Kaltoft; Carsten Geisler; Niels Ødum
Increased sensitivity to interferon-alpha in psoriatic T cells.
The Journal of investigative dermatology 2005;125(5):936-44.
2005: Christine Brender; Paola Lovato; Viveca Horst Sommer; Anders Woetmann; A-M Mathiesen; Carsten Geisler; Mariusz A Wasik; Niels Ødum
Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha.
Leukemia 2005;19(2):209-13.
2004: Jens Peter H Lauritsen; Charlotte Menné Bonefeld; Marina von Essen; Martin Weiss Nielsen; Anette Bødker Rasmussen; Niels Ødum; Jes Dietrich; Carsten Geisler
Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression.
Traffic (Copenhagen, Denmark) 2004;5(9):672-84.
2004: Marina von Essen; Charlotte Menné Bonefeld; Volkert Siersma; Anette Bødker Rasmussen; Jens Peter H Lauritsen; Bodil L Nielsen; Carsten Geisler
Constitutive and ligand-induced TCR degradation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):384-93.
2004: Anette Bødker Rasmussen; M-B Zocca; Charlotte Menné Bonefeld; Marina von Essen; Jens Peter H Lauritsen; Søren Tomra; Niels Ødum; Carsten Geisler
Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen.
Scandinavian journal of immunology 2004;59(2):220-7.
2004: Karsten Wessel Eriksen; Viveca Horst Sommer; Anders Woetmann; Anette Bødker Rasmussen; Christine Brender; Arne Svejgaard; Søren Skov; Carsten Geisler; Niels Ødum
Bi-phasic effect of interferon (IFN)-alpha: IFN-alpha up- and down-regulates interleukin-4 signaling in human T cells.
The Journal of biological chemistry 2004;279(1):169-76.
2004: Carsten Geisler
TCR trafficking in resting and stimulated T cells.
Critical reviews in immunology 2004;24(1):67-86.
2003: Charlotte Menné Bonefeld; Anette Bødker Rasmussen; Jens Peter H Lauritsen; Marina von Essen; Niels Ødum; Peter S Andersen; Carsten Geisler
TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):3003-9.
2003: Anders Woetmann; Johannes Brockdorff; Paola Lovato; Morten Nielsen; Vagn Leick; Klaus Rieneck; Arne Svejgaard; Carsten Geisler; Niels Ødum
Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling.
The Journal of biological chemistry 2003;278(5):2787-91.
2002: Jens Kastrup; Lars Østergaard Pedersen; Jes Dietrich; Jens Peter H Lauritsen; Charlotte Menné; Carsten Geisler
In vitro production and characterization of partly assembled human CD3 complexes.
Scandinavian journal of immunology 2002;56(5):436-42.
2002: Jes Dietrich; Charlotte Menné; Jens Peter H Lauritsen; Marina von Essen; Anette Bødker Rasmussen; Niels Ødum; Carsten Geisler
Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(11):5434-40.
2002: Marina von Essen; Charlotte Menné; Bodil L Nielsen; Jens Peter H Lauritsen; Jes Dietrich; Peter S Andersen; Klaus Karjalainen; Niels Ødum; Carsten Geisler
The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4519-23.
2002: Peter S Andersen; Peter Schuck; Eric Sundberg; Carsten Geisler; Klaus Karjalainen; Roy A Mariuzza
Quantifying the energetics of cooperativity in a ternary protein complex.
Biochemistry 2002;41(16):5177-84.
2002: Charlotte Menné; Tine Møller Sørensen; Volkert Siersma; Marina von Essen; Niels Ødum; Carsten Geisler
Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling.
European journal of immunology 2002;32(3):616-26.
2002: Morten Nielsen; Mogens H Nissen; Jens Gerwien; Mai-Britt Zocca; Helene M Rasmussen; Koichi Nakajima; Carsten Röpke; Carsten Geisler; Keld Kaltoft; Niels Ødum
Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3.
Blood 2002;99(3):973-7.
2001: Peter S Andersen; Charlotte Menné; Roy A Mariuzza; Carsten Geisler; Klaus Karjalainen
A response calculus for immobilized T cell receptor ligands.
The Journal of biological chemistry 2001;276(52):49125-32.
2001: Peter S Andersen; Carsten Geisler; Soren Buus; Roy A Mariuzza; Klaus Karjalainen
Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens.
The Journal of biological chemistry 2001;276(36):33452-7.
2001: Karsten Wessel Eriksen; Keld Kaltoft; Gerd Just Mikkelsen; Morten Nielsen; Qian Zhang; Carsten Geisler; Mogens H Nissen; Carsten Röpke; Mariusz A Wasik; Niels Odum
Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells.
Leukemia 2001;15(5):787-93.
2001: Charlotte Menné; Jens Peter H Lauritsen; Jes Dietrich; Jens Kastrup; A K Wegener; Peter S Andersen; Niels Odum; Carsten Geisler
T-cell receptor downregulation by ceramide-induced caspase activation and cleavage of the zeta chain.
Scandinavian journal of immunology 2001;53(2):176-83.
2001: Johannes Brockdorff; Haihua Gu; Tomas Mustelin; Keld Kaltoft; Carsten Geisler; Carsten Röpke; Niels Ødum
Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a.
Experimental and clinical immunogenetics 2001;18(2):86-95.
2001: Christine Brender; Morten Nielsen; Carsten Röpke; Mogens H Nissen; Arne Svejgaard; Nils Billestrup; Carsten Geisler; Niels Ødum
Interferon-alpha induces transient suppressors of cytokine signalling expression in human T cells.
Experimental and clinical immunogenetics 2001;18(2):80-5.
2001: Jens Peter H Lauritsen; Charlotte Menné; Jens Kastrup; Jes Dietrich; Carsten Geisler
Protein phosphatase 2A isotypes regulate cell surface expression of the T cell receptor.
Experimental and clinical immunogenetics 2001;18(1):24-33.
2000: Jens Peter H Lauritsen; Charlotte Menné; Jens Kastrup; Jes Dietrich; Niels Odum; Carsten Geisler
beta2-adaptin is constitutively de-phosphorylated by serine/threonine protein phosphatase PP2A and phosphorylated by a staurosporine-sensitive kinase.
Biochimica et biophysica acta 2000;1497(3):297-307.
2000: Charlotte Menné; Jens Peter H Lauritsen; Jes Dietrich; Jens Kastrup; A M Wegener; Niels Odum; Carsten Geisler
Ceramide-induced TCR up-regulation.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3065-72.
2000: MB Nielsen; Alexei F Kirkin; DJ Loftus; Mogens H Nissen; L Rivoltini; Jesper Zeuthen; Carsten Geisler; Niels Odum
Amino acid substitutions in the melanoma antigen recognized by T cell 1 peptide modulate cytokine responses in melanoma-specific T cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2000;23(4):405-11.
2000: Johannes Brockdorff; Morten Nielsen; Keld Kaltoft; Tomas Mustelin; Carsten Röpke; A Svejaard; Carsten Geisler; Niels Odum
Lck is involved in interleukin-2 induced proliferation but not cell survival in human T cells through a MAP kinase-independent pathway.
European cytokine network 2000;11(2):225-31.
2000: MD Christensen; Carsten Geisler
Recruitment of SHP-1 protein tyrosine phosphatase and signalling by a chimeric T-cell receptor-killer inhibitory receptor.
Scandinavian journal of immunology 2000;51(6):557-64.
2000: Jens Kastrup; Jens Peter H Lauritsen; Charlotte Menné; Jes Dietrich; Carsten Geisler
The phosphatase domains of CD45 are required for ligand induced T-cell receptor downregulation.
Scandinavian journal of immunology 2000;51(5):491-6.
1999: Anders Woetmann; Morten Nielsen; Søren T Christensen; Johannes Brockdorff; Keld Kaltoft; Anne-Marie Engel; Søren Skov; Christine Brender; Carsten Geisler; Arne Svejgaard; Jørgen Rygaard; Vagn Leick; Niels Odum
Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(19):10620-5.
1999: Jens Gerwien; Morten Nielsen; tord labuda; Mogens H Nissen; Arne Svejgaard; Carsten Geisler; Carsten Röpke; Niels Odum
Cutting edge: TCR stimulation by antibody and bacterial superantigen induces Stat3 activation in human T cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(4):1742-5.
1999: Morten Nielsen; Charlotte G Kaestel; Karsten Wessel Eriksen; Anders Woetmann; T Stokkedal; Keld Kaltoft; Carsten Geisler; Carsten Röpke; Niels Odum
Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells.
Leukemia 1999;13(5):735-8.
1999: Jes Dietrich; Jens Kastrup; Jens Peter H Lauritsen; Charlotte Menné; F von Bülow; Carsten Geisler
TCRzeta is transported to and retained in the Golgi apparatus independently of other TCR chains: implications for TCR assembly.
European journal of immunology 1999;29(5):1719-28.
1998: MB Nielsen; Niels Odum; Jens Gerwien; Arne Svejgaard; Klaus Bendtzen; S Bregentholt; Carsten Röpke; Carsten Geisler; M Dohlsten; Keld Kaltoft
Staphylococcal enterotoxin-A directly stimulates signal transduction and interferon-gamma production in psoriatic T-cell lines.
Tissue antigens 1998;52(6):530-8.
1998: Jes Dietrich; Carsten Geisler
T cell receptor zeta allows stable expression of receptors containing the CD3gamma leucine-based receptor-sorting motif.
The Journal of biological chemistry 1998;273(41):26281-4.
1998: Jes Dietrich; T Bäckström; Jens Peter H Lauritsen; Jens Kastrup; MD Christensen; F von Bülow; E Palmer; Carsten Geisler
The phosphorylation state of CD3gamma influences T cell responsiveness and controls T cell receptor cycling.
The Journal of biological chemistry 1998;273(37):24232-8.
1998: C L Amos; Anders Woetmann; Morten Nielsen; Carsten Geisler; Niels Odum; Barry L Brown; P R M Dobson
The role of caspase 3 and BclxL in the action of interleukin 7 (IL-7): a survival factor in activated human T cells.
Cytokine 1998;10(9):662-8.
1998: Carsten Geisler; Jes Dietrich; Bodil L Nielsen; Jens Kastrup; Jens Peter H Lauritsen; Niels Odum; MD Christensen
Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane.
The Journal of biological chemistry 1998;273(33):21316-23.
1998: Jens Peter H Lauritsen; MD Christensen; Jes Dietrich; Jens Kastrup; Niels Odum; Carsten Geisler
Two distinct pathways exist for down-regulation of the TCR.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):260-7.
1998: Johannes Brockdorff; S B Kanner; Morten Nielsen; N Borregaard; Carsten Geisler; Arne Svejgaard; Niels Odum
Interleukin-2 induces beta2-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB).
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6959-64.
1998: DJ Loftus; Paola Squarcina; M B Nielsen; Carsten Geisler; Chiara Castelli; Niels Odum; Ettore Appella; Giorgio Parmiani; Licia Rivoltini
Peptides derived from self-proteins as partial agonists and antagonists of human CD8+ T-cell clones reactive to melanoma/melanocyte epitope MART1(27-35).
Cancer research 1998;58(11):2433-9.
1998: Jens Gerwien; Keld Kaltoft; Morten Nielsen; MB Nielsen; Arne Svejgaard; Carsten Geisler; Carsten Röpke; Niels Odum
Staphylococcus enterotoxin A modulates interleukin 15-induced signaling and mitogenesis in human T cells.
Tissue antigens 1998;51(2):164-73.
1998: Morten Nielsen; Jens Gerwien; Carsten Geisler; Carsten Röpke; Arne Svejgaard; Niels Odum
MHC class II ligation induces CD58 (LFA-3)-mediated adhesion in human T cells.
Experimental and clinical immunogenetics 1998;15(2):61-8.
1998: Licia Rivoltini; DJ Loftus; Paola Squarcina; Chiara Castelli; Francesca Rini; Flavio Arienti; Filiberto Belli; F M Marincola; Carsten Geisler; A Borsatti; Ettore Appella; Giorgio Parmiani
Recognition of melanoma-derived antigens by CTL: possible mechanisms involved in down-regulating anti-tumor T-cell reactivity.
Critical reviews in immunology 1998;18(1-2):55-63.
1997: Jes Dietrich; Jens Kastrup; Bodil L Nielsen; Niels Odum; Carsten Geisler
Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro.
The Journal of cell biology 1997;138(2):271-81.
1997: Morten Nielsen; Keld Kaltoft; M Nordahl; Carsten Röpke; Carsten Geisler; Tomas Mustelin; P Dobson; Arne Svejgaard; Niels Odum
Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(13):6764-9.
1997: Johannes Brockdorff; Morten Nielsen; Arne Svejgaard; P Dobson; Carsten Röpke; Carsten Geisler; Niels Odum
Protein phosphatase 2A plays a critical role in interleukin-2-induced beta 2-integrin dependent homotypic adhesion in human CD4+ T cell lines.
Cytokine 1997;9(5):333-9.
1997: Johannes Brockdorff; Morten Nielsen; P Dobson; Carsten Geisler; Carsten Röpke; Arne Svejgaard; Niels Odum
Interleukin 2 induces a transient downregulation of protein phosphatase 1 and 2A activity in human T cells.
Tissue antigens 1997;49(3 Pt 1):228-35.
1996: Morten Nielsen; Arne Svejgaard; Søren Skov; P Dobson; Klaus Bendtzen; Carsten Geisler; Niels Odum
IL-2 induces beta2-integrin adhesion via a wortmannin/LY294002-sensitive, rapamycin-resistant pathway. Phosphorylation of a 125-kilodalton protein correlates with induction of adhesion, but not mitogenesis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5350-8.
1996: Jes Dietrich; X Hou; A M Wegener; LO Pedersen; Niels Odum; Carsten Geisler
Molecular characterization of the di-leucine-based internalization motif of the T cell receptor.
The Journal of biological chemistry 1996;271(19):11441-8.
1996: Jes Dietrich; A Neisig; X Hou; A M Wegener; Michael Gajhede; Carsten Geisler
Role of CD3 gamma in T cell receptor assembly.
The Journal of cell biology 1996;132(3):299-310.
1995: A M Wegener; X Hou; Jes Dietrich; Carsten Geisler
Distinct domains of the CD3-gamma chain are involved in surface expression and function of the T cell antigen receptor.
The Journal of biological chemistry 1995;270(9):4675-80.
1994: S Caspar-Bauguil; Jacques Arnaud; A Huchenq; W R Hein; Carsten Geisler; Bent Rubin
A highly conserved phenylalanine in the alpha, beta-T cell receptor (TCR) constant region determines the integrity of TCR/CD3 complexes.
Scandinavian journal of immunology 1994;40(3):323-36.
1994: S Caspar-Bauguil; Jacques Arnaud; C Gouaillard; X Hou; Carsten Geisler; Bent Rubin
Functionally important amino acids in the TCR revealed by immunoselection of membrane TCR-negative T cells.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(11):5288-98.
1994: X Hou; Jes Dietrich; J Kuhlmann; A M Wegener; Carsten Geisler
Structure of the T cell receptor in a Ti alpha V beta 2, alpha V beta 8-positive T cell line.
European journal of immunology 1994;24(5):1228-33.
1993: A Neisig; A Vangsted; Jesper Zeuthen; Carsten Geisler
Assembly of the T-cell antigen receptor. Participation of the CD3 omega chain.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(2):870-9.
1993: A Vangsted; A Neisig; Håkan Wallin; Jesper Zeuthen; Carsten Geisler
Induction of CD3 delta epsilon omega by phorbol 12-myristate 13-acetate.
European journal of immunology 1993;23(6):1351-7.
1993: Mogens H Claesson; Steen Dissing; T Tscherning; Carsten Geisler
T-cell activation. V. Anti-major histocompatibility complex class I antibody-induced activation and clonal abortion in Jurkat T-leukaemic cells.
Immunology 1993;78(3):444-8.
1993: J Kuhlmann; S Caspar-Bauguil; Carsten Geisler; Bent Rubin
Characterization of T cell receptor assembly and expression in a Ti gamma delta-positive cell line.
European journal of immunology 1993;23(2):487-93.
1993: J Kuhlmann; Carsten Geisler
Structure of the T-cell receptor in a Ti alpha beta, Ti gamma delta double positive T-cell line.
Scandinavian journal of immunology 1993;37(2):271-5.
1992: Carsten Geisler; Bent Rubin; S Caspar-Bauguil; E Champagne; A Vangsted; X Hou; Michael Gajhede
Structural mutations of C-domains in members of the Ig superfamily. Consequences for the interactions between the T cell antigen receptor and the zeta 2 homodimer.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(11):3469-77.
1992: Carsten Geisler
Failure to synthesize the CD3-gamma chain. Consequences for T cell antigen receptor assembly, processing, and expression.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(8):2437-45.
1991: N Illum; E Ralfkiaer; G Pallesen; Carsten Geisler
Phenotypical and functional characterization of double-negative (CD4-CD8-) alpha beta T-cell receptor positive cells from an immunodeficient patient.
Scandinavian journal of immunology 1991;34(5):635-45.
1991: P Philip; Carsten Geisler; MM Hansen; H Hasselbalch; Bjarne E Christensen; A Drivsholm; B Lund; J B Nielsen; K B Jensen; E Andersen
Aberrations of chromosome 6 in 193 newly diagnosed untreated cases of chronic lymphocytic leukemia.
Cancer genetics and cytogenetics 1991;53(1):35-43.
1990: Carsten Geisler; J Kuhlmann; T Møller; T Plesner; B Rubin
Transmembrane signalling via HLA-DR molecules on T cells from a Sezary T-cell leukaemia line.
Scandinavian journal of immunology 1990;32(6):731-5.
1990: Carsten Geisler; J Schøller; M A Wahi; B Rubin; A Weiss
Association of the human CD3-zeta chain with the alpha beta-T cell receptor/CD3 complex. Clues from a T cell variant with a mutated T cell receptor-alpha chain.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(6):1761-7.
1990: Niels Odum; L P Ryder; J Georgsen; B K Jakobsen; Carsten Geisler; J Møller; Niels Morling; Ebbe Dickmeiss; Arne Svejgaard
Accessory signals in T-T cell interactions between antigen- and alloantigen-specific, human memory T cells generated in vitro.
Scandinavian journal of immunology 1990;31(6):717-28.
1990: A M Wegener; B Holm; Carsten Geisler; B Rubin
Cellular and molecular characteristics of transformed T cells from an antigen-specific T-cell line.
Scandinavian journal of immunology 1990;31(5):645-56.
1990: Steen Dissing; Carsten Geisler; B Rubin; T Plesner; Mogens H Claesson
T cell activation. II. Activation of human T lymphoma cells by cross-linking of their MHC class I antigens.
Cellular immunology 1990;126(1):196-210.
1989: Carsten Geisler; J Kuhlmann; B Rubin
Assembly, intracellular processing, and expression at the cell surface of the human alpha beta T cell receptor/CD3 complex. Function of the CD3-zeta chain.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(12):4069-77.
1989: Carsten Geisler; J Kuhlmann; T Plesner; B Rubin
Failure to synthesize the human T-cell CD3-zeta chain and its consequence for the T-cell receptor-CD3 complex expression.
Scandinavian journal of immunology 1989;30(2):191-7.
1989: Carsten Geisler; G Pallesen; P Platz; Niels Odum; Ebbe Dickmeiss; L P Ryder; Arne Svejgaard; T Plesner; J K Larsen; Christian Koch
Novel primary thymic defect with T lymphocytes expressing gamma delta T cell receptor.
Journal of clinical pathology 1989;42(7):705-11.
1989: Niels Odum; Ebbe Dickmeiss; B Hofmann; B K Jakobsen; Niels Morling; P Platz; L P Ryder; Carsten Geisler; Arne Svejgaard
Alloactivated HLA class II-positive T-cell lines induce IL-2 reactivity but lack accessory cell function in mixed leukocyte culture.
Human immunology 1989;25(2):135-48.
1989: Carsten Geisler; J Møller; T Plesner; Ebbe Dickmeiss; G Pallesen; J K Larsen; N Jacobsen; A Svejgaard
Specific depletion of mature T lymphocytes from human bone marrow.
Scandinavian journal of immunology 1989;29(5):617-25.
1989: B Rubin; Carsten Geisler; J Kuhlmann; T Plesner
Fractionation of T cell subsets on Ig anti-Ig columns: isolation of helper T cells from nonresponder mice, demonstration of antigen-specific T suppressor cells, and selection of CD-3 negative variants of Jurkat T cells.
Cellular immunology 1989;119(2):327-40.
1988: Carsten Geisler; J K Larsen; T Plesner
Identification of alpha beta and gamma delta T cell receptor-positive cells.
Scandinavian journal of immunology 1988;28(6):741-5.
1988: Niels Odum; B Hofmann; Niels Morling; P Platz; L P Ryder; N Tvede; Carsten Geisler; Arne Svejgaard
Differences between primed allogeneic T-cell responses and the primary mixed leucocyte reaction. Primed T cells become independent of the blocking effects of monoclonal antibodies against IL-1 beta and the CD5, CD11a (LFA-1), and CD11c (p 150,95) molecules.
Scandinavian journal of immunology 1988;27(4):405-11.
1988: Carsten Geisler; J K Larsen; E Andersen; Henrik Birgens; Bjarne E Christensen; A Drivsholm; MM Hansen; P Hokland; K B Jensen; T Plesner
The CLL2 study: preliminary results of flow cytometry immunophenotyping in the first 500 patients.
Nouvelle revue française d'hématologie 1988;30(5-6):335-7.
1988: MM Hansen; E Andersen; Bjarne E Christensen; I Christiansen; Carsten Geisler; D Kristensen; K B Jensen; P Junker
CHOP versus prednisolone + chlorambucil in chronic lymphocytic leukemia (CLL): preliminary results of a randomized multicenter study.
Nouvelle revue française d'hématologie 1988;30(5-6):433-6.
1987: Y Merrick; L P Rasmussen; Carsten Geisler; B V Jensen; B Guldhammer
Hypereosinophilia in a patient with acute lymphoblastic leukemia.
Medical oncology and tumor pharmacotherapy 1987;4(2):97-100.
1986: Carsten Geisler; P Philip; T Plesner; P Andersson; J Zeuthen; B Guldhammer; M M Hansen
Simultaneous presence of translocations t(14;18) and t(2;8) in a case of chronic lymphocytic leukemia.
Cancer genetics and cytogenetics 1986;22(1):35-44.
1985: H Hasselbalch; Henrik Birgens; Carsten Geisler; Niels Ebbe Hansen
Hypercalcaemia in the accelerated phase of chronic myelogenous leukaemia: no relationship to the phenotype of the blast cells.
Scandinavian journal of haematology 1985;35(3):333-8.
1983: Carsten Geisler; E Ralfkiaer; L Astrup; I Christensen; Ebbe Dickmeiss; M M Hansen; J K Larsen; J Petersen; T Plesner
Chronic lymphocytic leukaemia of T cell origin. Clinical variation possibly due to involvement of different T lymphocyte subpopulations.
Scandinavian journal of haematology 1983;31(2):109-21.
1983: M Wilken; T Plesner; Carsten Geisler; O J Bjerrum
Demonstration and partial characterization of chronic lymphocytic leukemia lymphocyte-associated antigens by crossed immunoelectrophoresis of Triton X-100 extracts.
Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology 1983;91(4):237-44.