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Robert Geisler

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Christopher M Dooley; Martina Konantz; Alessandro Mongera; Kaspar P Mueller; Stephan C F Neuhauss; Christiane Nüsslein-Volhard; Heinz Schwarz; Robert Geisler
Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease.
Uwe Strähle; Carsten Weiss; Hilda Witters; Robert Geisler; Petra Greiner; Henner Hollert; Sepand Rastegar; Stefan Scholz; Axel Schumacher; Ingrid Selderslaghs; Thomas Braunbeck
Zebrafish embryos as an alternative to animal experiments--a commentary on the definition of the onset of protected life stages in animal welfare regulations.
Helia B Schonthaler; Tamara A Franz-Odendaal; Corinne Hodel; Ines Gehring; Robert Geisler; Heinz Schwarz; Stephan C F Neuhauss; Ralf Dahm
The zebrafish mutant bumper shows a hyperproliferation of lens epithelial cells and fibre cell degeneration leading to functional blindness.

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All Publications

2013: Christopher M Dooley; Martina Konantz; Alessandro Mongera; Kaspar P Mueller; Stephan C F Neuhauss; Christiane Nüsslein-Volhard; Heinz Schwarz; Robert Geisler
Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease.
Pigment cell & melanoma research 2013;26(2):205-17.
2012: Uwe Strähle; Carsten Weiss; Hilda Witters; Robert Geisler; Petra Greiner; Henner Hollert; Sepand Rastegar; Stefan Scholz; Axel Schumacher; Ingrid Selderslaghs; Thomas Braunbeck
Zebrafish embryos as an alternative to animal experiments--a commentary on the definition of the onset of protected life stages in animal welfare regulations.
Reproductive toxicology (Elmsford, N.Y.) 2012;33(2):128-32.
2010: Helia B Schonthaler; Tamara A Franz-Odendaal; Corinne Hodel; Ines Gehring; Robert Geisler; Heinz Schwarz; Stephan C F Neuhauss; Ralf Dahm
The zebrafish mutant bumper shows a hyperproliferation of lens epithelial cells and fibre cell degeneration leading to functional blindness.
Mechanisms of development 2010;127(3-4):203-19.
2009: Caghan Kizil; Georg W Otto; Robert Geisler; Christiane Nüsslein-Volhard; Christopher L Antos
Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration.
Developmental biology 2009;325(2):329-40.
2008: Susana Lopes; Xueyan Yang; Jeanette Müller; Thomas J Carney; Anthony R McAdow; Gerd-Jörg Rauch; Arie S Jacoby; Laurence D Hurst; Mariana Delfino-Machín; Pascal Haffter; Robert Geisler; Stephen L Johnson; Andrew Ward; Robert Neil Kelsh
Leukocyte tyrosine kinase functions in pigment cell development.
PLoS genetics 2008;4(3):e1000026.
2008: Helia B Schonthaler; Valerie C Fleisch; Oliver Biehlmaier; Yuri V Makhankov; Oliver Rinner; Ronja Bahadori; Robert Geisler; Heinz Schwarz; Stephan Neuhauss; Ralf Dahm
The zebrafish mutant lbk/vam6 resembles human multisystemic disorders caused by aberrant trafficking of endosomal vesicles.
Development (Cambridge, England) 2008;135(2):387-99.
2007: Christelle Etard; Martine Behra; Nadine Fischer; David Hutcheson; Robert Geisler; Uwe Strähle
The UCS factor Steif/Unc-45b interacts with the heat shock protein Hsp90a during myofibrillogenesis.
Developmental biology 2007;308(1):133-43.
2007: Yanmei Liu; Linsen Du; Motomi Osato; Eng Hui Teo; Feng Qian; Hao Jin; Fenghua Zhen; Jin Xu; Lin Guo; Honghui Huang; Jun Chen; Robert Geisler; Yun-Jin Jiang; Jinrong Peng; Zilong Wen
The zebrafish udu gene encodes a novel nuclear factor and is essential for primitive erythroid cell development.
Blood 2007;110(1):99-106.
2007: Doris Voelker; christoph Vess; Michaela Tillmann; Roland Nagel; Georg W Otto; Robert Geisler; Kristin Schirmer; Stefan Scholz
Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae.
Aquatic toxicology (Amsterdam, Netherlands) 2007;81(4):355-64.
2006: Ralf Dahm; Robert Geisler
Learning from small fry: the zebrafish as a genetic model organism for aquaculture fish species.
Marine biotechnology (New York, N.Y.) 2006;8(4):329-45.
2005: Christelle Etard; Martine Behra; Raymond Ertzer; Nadine Fischer; Suresh Jesuthasan; Patrick Blader; Robert Geisler; Uwe Strähle
Mutation in the delta-subunit of the nAChR suppresses the muscle defects caused by lack of Dystrophin.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;234(4):1016-25.
2005: Dörthe Jülich; Chiaw Hwee Lim; Jennifer Round; Claudia Nicolaije; Joshua Schroeder; Alexander Davies; Robert Geisler; Julian Lewis; Yun-Jin Jiang; Scott A Holley
beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation.
Developmental biology 2005;286(2):391-404.
2005: Helia B Schonthaler; Johanna M Lampert; Johannes Von Lintig; Heinz Schwarz; Robert Geisler; Stephan Neuhauss
A mutation in the silver gene leads to defects in melanosome biogenesis and alterations in the visual system in the zebrafish mutant fading vision.
Developmental biology 2005;284(2):421-36.
2005: Mahendra Sonawane; Yamila Carpio; Robert Geisler; Heinz Schwarz; Hans-Martin Maischein; Christiane Nuesslein-Volhard
Zebrafish penner/lethal giant larvae 2 functions in hemidesmosome formation, maintenance of cellular morphology and growth regulation in the developing basal epidermis.
Development (Cambridge, England) 2005;132(14):3255-65.
2005: Jochen A Stadler; Alena Shkumatava; William H J Norton; Marlene J Rau; Robert Geisler; Sabine Fischer; Carl J Neumann
Histone deacetylase 1 is required for cell cycle exit and differentiation in the zebrafish retina.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;233(3):883-9.
2005: Annemarie H Meijer; Fons J Verbeek; Enrique Salas-Vidal; Maximiliano Corredor-Adámez; Jeroen Bussman; Astrid van der Sar; Georg W Otto; Robert Geisler; Herman P Spaink
Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection.
Molecular immunology 2005;42(10):1185-203.
2005: Dörthe Jülich; Robert Geisler; Scott A Holley
Integrinalpha5 and delta/notch signaling have complementary spatiotemporal requirements during zebrafish somitogenesis.
Developmental cell 2005;8(4):575-86.
2005: William H J Norton; Maryam Mangoli; Zsolt Lele; Hans-Martin Pogoda; Brianne Diamond; Sara Mercurio; Claire Russell; Hiroki Teraoka; Heather L Stickney; Gerd-Jörg Rauch; Carl-Philipp Heisenberg; Corinne Houart; Thomas F Schilling; Hans-Georg Frohnhoefer; Sepand Rastegar; Carl J Neumann; R Mark Gardiner; Uwe Strähle; Robert Geisler; Michelle Rees; William S Talbot; Stephen W Wilson
Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphé neurones and cranial motoneurones.
Development (Cambridge, England) 2005;132(4):645-58.
2004: Jeong-Soo Lee; Sophia von der Hardt; Melissa A Rusch; Sally E Stringer; Heather L Stickney; William S Talbot; Robert Geisler; Christiane Nüsslein-Volhard; Scott B Selleck; Chi-Bin Chien; Henry Roehl
Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer).
Neuron 2004;44(6):947-60.
2004: Christian Söllner; Heinz Schwarz; Robert Geisler; Teresa Nicolson
Mutated otopetrin 1 affects the genesis of otoliths and the localization of Starmaker in zebrafish.
Development genes and evolution 2004;214(12):582-90.
2004: Christian Wolff; Sudipto Roy; Katharine E Lewis; Heike Schauerte; Gerd Joerg-Rauch; Annette Kirn; Christian Weiler; Robert Geisler; Pascal Haffter; Philip Ingham
iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo.
Genes & development 2004;18(13):1565-76.
2004: Christian Söllner; Gerd-Jörg Rauch; Jan Siemens; Robert Geisler; Stephan C Schuster; Ulrich Müller; Teresa Nicolson
Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells.
Nature 2004;428(6986):955-9.
2004: Jagan Srinivasan; Georg W Otto; Ulrich Kahlow; Robert Geisler; Ralf J Sommer
AppaDB: an AcedB database for the nematode satellite organism Pristionchus pacificus.
Nucleic acids research 2004;32(Database issue):D421-2.
2003: Robert D Knight; Sreelaja Nair; Sarah S Nelson; Ali Afshar; Yashar Javidan; Robert Geisler; Gerd-Jörg Rauch; Thomas F Schilling
lockjaw encodes a zebrafish tfap2a required for early neural crest development.
Development (Cambridge, England) 2003;130(23):5755-68.
2003: Tatjana Piotrowski; Dae-gwon Ahn; Thomas F Schilling; Sreelaja Nair; Ilya Ruvinsky; Robert Geisler; Gerd-Jörg Rauch; Pascal Haffter; Leonard I Zon; Yi Zhou; Helen Foott; Igor B Dawid; Robert K Ho
The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humans.
Development (Cambridge, England) 2003;130(20):5043-52.
2003: Ronja Bahadori; Matthias Huber; Oliver Rinner; Mathias W Seeliger; Silke Geiger-Rudolph; Robert Geisler; Stephan Neuhauss
Retinal function and morphology in two zebrafish models of oculo-renal syndromes.
The European journal of neuroscience 2003;18(6):1377-86.
2003: Robert J Bink; Hiroko Habuchi; Zsolt Lele; Edward Dolk; Jos Joore; Gerd-Jörg Rauch; Robert Geisler; Stephen W Wilson; Jeroen den Hertog; Koji Kimata; Danica Zivkovic
Heparan sulfate 6-o-sulfotransferase is essential for muscle development in zebrafish.
The Journal of biological chemistry 2003;278(33):31118-27.
2003: Holger Knaut; Christian Werz; Robert Geisler; Christiane Nüsslein-Volhard
A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor.
Nature 2003;421(6920):279-82.
2002: Zsolt Lele; Anja Folchert; Miguel L Concha; Gerd-Jörg Rauch; Robert Geisler; Frédéric M Rosa; Stephen W Wilson; Matthias Hammerschmidt; Laure Bally-Cuif
parachute/n-cadherin is required for morphogenesis and maintained integrity of the zebrafish neural tube.
Development (Cambridge, England) 2002;129(14):3281-94.
2002: Heiner Grandel; Klaus Lun; Gerd-Jörg Rauch; Muriel Rhinn; Tatjana Piotrowski; Corinne Houart; Paolo Sordino; Axel M Küchler; Stefan Schulte-Merker; Robert Geisler; Nigel Holder; Stephen W Wilson; Michael Brand
Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud.
Development (Cambridge, England) 2002;129(12):2851-65.
2002: Scott A Holley; Dörthe Jülich; Gerd-Jörg Rauch; Robert Geisler; Christiane Nüsslein-Volhard
her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis.
Development (Cambridge, England) 2002;129(5):1175-83.
2001: Kirsten A Dutton; A Pauliny; Susana Lopes; stone elworthy; Thomas J Carney; J Rauch; Robert Geisler; Pascal Haffter; Robert Neil Kelsh
Zebrafish colourless encodes sox10 and specifies non-ectomesenchymal neural crest fates.
Development (Cambridge, England) 2001;128(21):4113-25.
2001: Gerrit Begemann; Thomas F Schilling; Gerd-Jörg Rauch; Robert Geisler; Philip Ingham
The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain.
Development (Cambridge, England) 2001;128(16):3081-94.
2001: Carl-Philipp Heisenberg; Corinne Houart; Masaya Take-Uchi; Gerd-Jörg Rauch; Neville Young; Pedro Coutinho; Ichiro Masai; Luca Caneparo; Miguel L Concha; Robert Geisler; T C Dale; Stephen W Wilson; Derek L Stemple
A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon.
Genes & development 2001;15(11):1427-34.
2001: Hermann Bauer; Zsolt Lele; Gerd-Jörg Rauch; Robert Geisler; Matthias Hammerschmidt
The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo.
Development (Cambridge, England) 2001;128(6):849-58.
2000: Holger Sültmann; Akie Sato; BW Murray; Naoko Takezaki; Robert Geisler; Gerd-Jörg Rauch; Jan Klein
Conservation of Mhc class III region synteny between zebrafish and human as determined by radiation hybrid mapping.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(12):6984-93.
2000: S Ernest; Gerd-Jörg Rauch; Pascal Haffter; Robert Geisler; Christine Petit; Teresa Nicolson
Mariner is defective in myosin VIIA: a zebrafish model for human hereditary deafness.
Human molecular genetics 2000;9(14):2189-96.
2000: Scott A Holley; Robert Geisler; Christiane Nüsslein-Volhard
Control of her1 expression during zebrafish somitogenesis by a delta-dependent oscillator and an independent wave-front activity.
Genes & development 2000;14(13):1678-90.
2000: Carl-Philipp Heisenberg; Masazumi Tada; Gerd-Jörg Rauch; Leonor Saúde; Miguel L Concha; Robert Geisler; Derek L Stemple; J C Smith; Stephen W Wilson
Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation.
Nature 2000;405(6782):76-81.
1999: Richard I Dorsky; A Snyder; C J Cretekos; David Jonah Grunwald; Robert Geisler; Pascal Haffter; Randall T Moon; David W Raible
Maternal and embryonic expression of zebrafish lef1.
Mechanisms of development 1999;86(1-2):147-50.