Martin Gellert

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Grundy Gabrielle J; Ramón-Maiques Santiago; Dimitriadis Emilios K; Kotova Svetlana; Biertümpfel Christian; Heymann J Bernard; Steven Alasdair C; Gellert Martin; Yang Wei
Initial stages of V(D)J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex.
Grundy Gabrielle J; Hesse Joanne E; Gellert Martin
Requirements for DNA hairpin formation by RAG1/2.
Jones Jessica M; Gellert Martin
Autoubiquitylation of the V(D)J recombinase protein RAG1.

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2009: Grundy Gabrielle J; Ramón-Maiques Santiago; Dimitriadis Emilios K; Kotova Svetlana; Biertümpfel Christian; Heymann J Bernard; Steven Alasdair C; Gellert Martin; Yang Wei
Initial stages of V(D)J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex.
Molecular cell 2009;35(2):217-27.
2007: Grundy Gabrielle J; Hesse Joanne E; Gellert Martin
Requirements for DNA hairpin formation by RAG1/2.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3078-83.
2003: Jones Jessica M; Gellert Martin
Autoubiquitylation of the V(D)J recombinase protein RAG1.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15446-51.
2003: Modesti Mauro; Junop Murray S; Ghirlando Rodolfo; van de Rakt Mandy; Gellert Martin; Yang Wei; Kanaar Roland
Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive.
Journal of molecular biology 2003;334(2):215-28.
2002: Shih I-hung; Melek Meni; Jayaratne Nadeesha D; Gellert Martin
Inverse transposition by the RAG1 and RAG2 proteins: role reversal of donor and target DNA.
The EMBO journal 2002;21(23):6625-33.
2002: Jones Jessica M; Gellert Martin
Ordered assembly of the V(D)J synaptic complex ensures accurate recombination.
The EMBO journal 2002;21(15):4162-71.
2002: Melek Meni; Jones Jessica M; O'Dea Mary H; Pais Godwin; Burke Terrence R; Pommier Yves; Neamati Nouri; Gellert Martin
Effect of HIV integrase inhibitors on the RAG1/2 recombinase.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):134-7.
2002: Gellert Martin
V(D)J recombination: RAG proteins, repair factors, and regulation.
Annual review of biochemistry 2002;71():101-32.
2001: Jones J M; Gellert M
Intermediates in V(D)J recombination: a stable RAG1/2 complex sequesters cleaved RSS ends.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):12926-31.
2001: Jones J M; Gellert M; Yang W
A Ku bridge over broken DNA.
Structure (London, England : 1993) 2001;9(10):881-4.
2001: Paull T T; Cortez D; Bowers B; Elledge S J; Gellert M
Direct DNA binding by Brca1.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6086-91.
2000: Junop M S; Modesti M; Guarné A; Ghirlando R; Gellert M; Yang W
Crystal structure of the Xrcc4 DNA repair protein and implications for end joining.
The EMBO journal 2000;19(22):5962-70.
2000: Paull T T; Rogakou E P; Yamazaki V; Kirchgessner C U; Gellert M; Bonner W M
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage.
Current biology : CB 2000;10(15):886-95.
2000: Melek M; Gellert M
RAG1/2-mediated resolution of transposition intermediates: two pathways and possible consequences.
Cell 2000;101(6):625-33.
2000: Paull T T; Gellert M
A mechanistic basis for Mre11-directed DNA joining at microhomologies.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6409-14.
1999: Paull T T; Gellert M
Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex.
Genes & development 1999;13(10):1276-88.
1999: Modesti M; Hesse J E; Gellert M
DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity.
The EMBO journal 1999;18(7):2008-18.
1999: Bahassi E M; O'Dea M H; Allali N; Messens J; Gellert M; Couturier M
Interactions of CcdB with DNA gyrase. Inactivation of Gyra, poisoning of the gyrase-DNA complex, and the antidote action of CcdA.
The Journal of biological chemistry 1999;274(16):10936-44.
1999: Gellert M; Hesse J E; Hiom K; Melek M; Modesti M; Paull T T; Ramsden D A; van Gent D C
V(D)J recombination: links to transposition and double-strand break repair.
Cold Spring Harbor symposia on quantitative biology 1999;64():161-7.
1998: Hiom K; Melek M; Gellert M
DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations.
Cell 1998;94(4):463-70.
1998: Hiom K; Gellert M
Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination.
Molecular cell 1998;1(7):1011-9.
1998: Paull T T; Gellert M
The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks.
Molecular cell 1998;1(7):969-79.
1998: Melek M; Gellert M; van Gent D C
Rejoining of DNA by the RAG1 and RAG2 proteins.
Science (New York, N.Y.) 1998;280(5361):301-3.
1998: Ramsden D A; Gellert M
Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks.
The EMBO journal 1998;17(2):609-14.
1997: Critchlow S E; O'Dea M H; Howells A J; Couturier M; Gellert M; Maxwell A
The interaction of the F plasmid killer protein, CcdB, with DNA gyrase: induction of DNA cleavage and blocking of transcription.
Journal of molecular biology 1997;273(4):826-39.
1997: Ramsden D A; Paull T T; Gellert M
Cell-free V(D)J recombination.
Nature 1997;388(6641):488-91.
1997: van Gent D C; Hiom K; Paull T T; Gellert M
Stimulation of V(D)J cleavage by high mobility group proteins.
The EMBO journal 1997;16(10):2665-70.
1997: Krah R; O'Dea M H; Gellert M
Reverse gyrase from Methanopyrus kandleri. Reconstitution of an active extremozyme from its two recombinant subunits.
The Journal of biological chemistry 1997;272(21):13986-90.
1997: Ramsden D A; van Gent D C; Gellert M
Specificity in V(D)J recombination: new lessons from biochemistry and genetics.
Current opinion in immunology 1997;9(1):114-20.
1997: Hiom K; Gellert M
A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage.
Cell 1997;88(1):65-72.
1997: Gellert M
Recent advances in understanding V(D)J recombination.
Advances in immunology 1997;64():39-64.
1996: Ramsden D A; McBlane J F; van Gent D C; Gellert M
Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage.
The EMBO journal 1996;15(12):3197-206.
1996: O'Dea M H; Tamura J K; Gellert M
Mutations in the B subunit of Escherichia coli DNA gyrase that affect ATP-dependent reactions.
The Journal of biological chemistry 1996;271(16):9723-9.
1996: van Gent D C; Ramsden D A; Gellert M
The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination.
Cell 1996;85(1):107-13.
1996: van Gent D C; Mizuuchi K; Gellert M
Similarities between initiation of V(D)J recombination and retroviral integration.
Science (New York, N.Y.) 1996;271(5255):1592-4.
1996: Bates A D; O'Dea M H; Gellert M
Energy coupling in Escherichia coli DNA gyrase: the relationship between nucleotide binding, strand passage, and DNA supercoiling.
Biochemistry 1996;35(5):1408-16.
1996: Krah R; Kozyavkin S A; Slesarev A I; Gellert M
A two-subunit type I DNA topoisomerase (reverse gyrase) from an extreme hyperthermophile.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(1):106-10.
1996: van Gent D C; McBlane J F; Ramsden D A; Sadofsky M J; Hesse J E; Gellert M
Initiation of V(D)J recombinations in a cell-free system by RAG1 and RAG2 proteins.
Current topics in microbiology and immunology 1996;217():1-10.
1995: McBlane J F; van Gent D C; Ramsden D A; Romeo C; Cuomo C A; Gellert M; Oettinger M A
Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.
Cell 1995;83(3):387-95.
1995: Nakajima P B; Menetski J P; Roth D B; Gellert M; Bosma M J
V-D-J rearrangements at the T cell receptor delta locus in mouse thymocytes of the alpha beta lineage.
Immunity 1995;3(5):609-21.
1995: Ramsden D A; Gellert M
Formation and resolution of double-strand break intermediates in V(D)J rearrangement.
Genes & development 1995;9(19):2409-20.
1995: Sadofsky M J; Hesse J E; van Gent D C; Gellert M
RAG-1 mutations that affect the target specificity of V(D)j recombination: a possible direct role of RAG-1 in site recognition.
Genes & development 1995;9(17):2193-9.
1995: van Gent D C; McBlane J F; Ramsden D A; Sadofsky M J; Hesse J E; Gellert M
Initiation of V(D)J recombination in a cell-free system.
Cell 1995;81(6):925-34.
1995: Gellert M; McBlane J F
Steps along the pathway of V (D)J recombination.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1995;347(1319):43-7.
1994: Sadofsky M J; Hesse J E; Gellert M
Definition of a core region of RAG-2 that is functional in V(D)J recombination.
Nucleic acids research 1994;22(10):1805-9.
1994: Kozyavkin S A; Krah R; Gellert M; Stetter K O; Lake J A; Slesarev A I
A reverse gyrase with an unusual structure. A type I DNA topoisomerase from the hyperthermophile Methanopyrus kandleri is a two-subunit protein.
The Journal of biological chemistry 1994;269(15):11081-9.
1994: Sadofsky M J; Hesse J E; McBlane J F; Gellert M
Expression and V(D)J recombination activity of mutated RAG-1 proteins.
Nucleic acids research 1994;22(3):550.
1994: Slesarev A I; Lake J A; Stetter K O; Gellert M; Kozyavkin S A
Purification and characterization of DNA topoisomerase V. An enzyme from the hyperthermophilic prokaryote Methanopyrus kandleri that resembles eukaryotic topoisomerase I.
The Journal of biological chemistry 1994;269(5):3295-303.
1993: Sadofsky M J; Hesse J E; McBlane J F; Gellert M
Expression and V(D)J recombination activity of mutated RAG-1 proteins.
Nucleic acids research 1993;21(24):5644-50.
1993: Slesarev A I; Stetter K O; Lake J A; Gellert M; Krah R; Kozyavkin S A
DNA topoisomerase V is a relative of eukaryotic topoisomerase I from a hyperthermophilic prokaryote.
Nature 1993;364(6439):735-7.
1992: Gellert M
V(D)J recombination gets a break.
Trends in genetics : TIG 1992;8(12):408-12.
1992: Roth D B; Menetski J P; Nakajima P B; Bosma M J; Gellert M
V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes.
Cell 1992;70(6):983-91.
1992: Tamura J K; Bates A D; Gellert M
Slow interaction of 5'-adenylyl-beta,gamma-imidodiphosphate with Escherichia coli DNA gyrase. Evidence for cooperativity in nucleotide binding.
The Journal of biological chemistry 1992;267(13):9214-22.
1992: Roth D B; Nakajima P B; Menetski J P; Bosma M J; Gellert M
V(D)J recombination in mouse thymocytes: double-strand breaks near T cell receptor delta rearrangement signals.
Cell 1992;69(1):41-53.
1992: Roth D B; Nakajima P B; Menetski J P; Bosma M J; Gellert M
Double-strand breaks associated with V(D)J recombination at the TCR delta locus in murine thymocytes.
Current topics in microbiology and immunology 1992;182():115-24.
1992: Gellert M
Molecular analysis of V(D)J recombination.
Annual review of genetics 1992;26():425-46.
1990: Tamura J K; Gellert M
Characterization of the ATP binding site on Escherichia coli DNA gyrase. Affinity labeling of Lys-103 and Lys-110 of the B subunit by pyridoxal 5'-diphospho-5'-adenosine.
The Journal of biological chemistry 1990;265(34):21342-9.
1990: Menetski J P; Gellert M
V(D)J recombination activity in lymphoid cell lines is increased by agents that elevate cAMP.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9324-8.
1990: Krueger S; Zaccai G; Wlodawer A; Langowski J; O'Dea M; Maxwell A; Gellert M
Neutron and light-scattering studies of DNA gyrase and its complex with DNA.
Journal of molecular biology 1990;211(1):211-20.
1989: Hesse J E; Lieber M R; Mizuuchi K; Gellert M
V(D)J recombination: a functional definition of the joining signals.
Genes & development 1989;3(7):1053-61.
1989: Lieber M R; Hesse J E; Lewis S; Bosma G C; Rosenberg N; Mizuuchi K; Bosma M J; Gellert M
Abnormal V(D)J recombination in murine severe combined immune deficiency: absence of coding joints and formation of alternative products. Abnormal V(D)J recombination in murine severe combined immune deficiency: absence of coding joints and formation of alternative products.
Current topics in microbiology and immunology 1989;152():69-75.
1988: Lewis S M; Hesse J E; Mizuuchi K; Gellert M
Novel strand exchanges in V(D)J recombination.
Cell 1988;55(6):1099-107.
1988: Lieber M R; Hesse J E; Mizuuchi K; Gellert M
Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(22):8588-92.
1988: Lieber M R; Hesse J E; Lewis S; Bosma G C; Rosenberg N; Mizuuchi K; Bosma M J; Gellert M
The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination.
Cell 1988;55(1):7-16.
1988: Westerhoff H V; O'Dea M H; Maxwell A; Gellert M
DNA supercoiling by DNA gyrase. A static head analysis.
Cell biophysics 1988;12():157-81.
1988: Lieber M R; Hesse J E; Mizuuchi K; Gellert M
Studies of V(D)J recombination with extrachromosomal substrates.
Current topics in microbiology and immunology 1988;137():94-9.
1987: Lieber M R; Hesse J E; Mizuuchi K; Gellert M
Developmental stage specificity of the lymphoid V(D)J recombination activity.
Genes & development 1987;1(8):751-61.
1987: Hesse J E; Lieber M R; Gellert M; Mizuuchi K
Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals.
Cell 1987;49(6):775-83.
1987: Garner M M; Felsenfeld G; O'Dea M H; Gellert M
Effects of DNA supercoiling on the topological properties of nucleosomes.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(9):2620-3.
1987: Adachi T; Mizuuchi M; Robinson E A; Appella E; O'Dea M H; Gellert M; Mizuuchi K
DNA sequence of the E. coli gyrB gene: application of a new sequencing strategy.
Nucleic acids research 1987;15(2):771-84.
1984: Mizuuchi K; Mizuuchi M; O'Dea M H; Gellert M
Cloning and simplified purification of Escherichia coli DNA gyrase A and B proteins.
The Journal of biological chemistry 1984;259(14):9199-201.
1984: Friedman D I; Plantefaber L C; Olson E J; Carver D; O'Dea M H; Gellert M
Mutations in the DNA gyrB gene that are temperature sensitive for lambda site-specific recombination, Mu growth, and plasmid maintenance.
Journal of bacteriology 1984;157(2):490-7.
1984: Friedman D I; Olson E J; Carver D; Gellert M
Synergistic effect of himA and gyrB mutations: evidence that him functions control expression of ilv and xyl genes.
Journal of bacteriology 1984;157(2):484-9.
1983: Gellert M; O'Dea M H; Mizuuchi K
Slow cruciform transitions in palindromic DNA.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(18):5545-9.
1983: Gellert M; Menzel R; Mizuuchi K; O'Dea M H; Friedman D I
Regulation of DNA supercoiling in Escherichia coli.
Cold Spring Harbor symposia on quantitative biology 1983;47 Pt 2():763-7.
1982: Mizuuchi K; Mizuuchi M; Gellert M
Cruciform structures in palindromic DNA are favored by DNA supercoiling.
Journal of molecular biology 1982;156(2):229-43.
1981: Fisher L M; Mizuuchi K; O'Dea M H; Ohmori H; Gellert M
Site-specific interaction of DNA gyrase with DNA.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(7):4165-9.
1981: Gellert M; Fisher L M; Ohmori H; O'Dea M H; Mizuuchi K
DNA gyrase: site-specific interactions and transient double-strand breakage of DNA.
Cold Spring Harbor symposia on quantitative biology 1981;45 Pt 1():391-8.
1980: Mizuuchi K; Fisher L M; O'Dea M H; Gellert M
DNA gyrase action involves the introduction of transient double-strand breaks into DNA.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(4):1847-51.

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Martin Gellert

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