Howard Gendelman

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Ghosh Anamitra; Roy Avik; Matras Joanna; Brahmachari Saurav; Gendelman Howard E; Pahan Kalipada
Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease.
Kraft-Terry Stephanie D; Buch Shilpa J; Fox Howard S; Gendelman Howard E
A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection.
Keblesh James P; Dou Huanyu; Gendelman Howard E; Xiong Huangui
4-Aminopyridine improves spatial memory in a murine model of HIV-1 encephalitis.

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All Publications

2009: Ghosh Anamitra; Roy Avik; Matras Joanna; Brahmachari Saurav; Gendelman Howard E; Pahan Kalipada
Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(43):13543-56.
2009: Kraft-Terry Stephanie D; Buch Shilpa J; Fox Howard S; Gendelman Howard E
A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection.
Neuron 2009;64(1):133-45.
2009: Keblesh James P; Dou Huanyu; Gendelman Howard E; Xiong Huangui
4-Aminopyridine improves spatial memory in a murine model of HIV-1 encephalitis.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2009;4(3):317-27.
2009: Joseph Jeymohan; Clifford David; Douglas Steven D; Fox Howard; Gendelman Howard E; Gonzalez-Scarano Francisco; Grant Igor; Major Eugene; McArthur Justin;
Planning Future Strategies for Domestic and International NeuroAIDS Research, July 24-25, 2008.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2009;4(3):283-97.
2009: Eggert Dawn; Dash Prasanta K; Serradji Nawal; Dong Chang-Zhi; Clayette Pascal; Heymans Francoise; Dou Huanyu; Gorantla Santhi; Gelbard Harris A; Poluektova Larisa; Gendelman Howard E
Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders.
Journal of neuroimmunology 2009;213(1-2):47-59.
2009: Nowacek Ari; Gendelman Howard E
NanoART, neuroAIDS and CNS drug delivery.
Nanomedicine (London, England) 2009;4(5):557-74.
2009: Nowacek Ari; Kosloski Lisa M; Gendelman Howard E
Neurodegenerative disorders and nanoformulated drug development.
Nanomedicine (London, England) 2009;4(5):541-55.
2009: Dou Huanyu; Grotepas Cassi B; McMillan JoEllyn M; Destache Christopher J; Chaubal Mahesh; Werling Jane; Kipp James; Rabinow Barrett; Gendelman Howard E
Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):661-9.
2009: Reynolds Ashley D; Stone David K; Mosley R Lee; Gendelman Howard E
Proteomic studies of nitrated alpha-synuclein microglia regulation by CD4+CD25+ T cells.
Journal of proteome research 2009;8(7):3497-511.
2009: Huang Xiuyan; Reynolds Ashley D; Mosley R Lee; Gendelman Howard E
CD 4+ T cells in the pathobiology of neurodegenerative disorders.
Journal of neuroimmunology 2009;211(1-2):3-15.
2009: Kiyota Tomomi; Yamamoto Masaru; Schroder Bryce; Jacobsen Michael T; Swan Russell J; Lambert Mary P; Klein William L; Gendelman Howard E; Ransohoff Richard M; Ikezu Tsuneya
AAV1/2-mediated CNS gene delivery of dominant-negative CCL2 mutant suppresses gliosis, beta-amyloidosis, and learning impairment of APP/PS1 mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(5):803-9.
2009: Schifitto Giovanni; Zhong Jianhui; Gill David; Peterson Derick R; Gaugh Michelle D; Zhu Tong; Tivarus Madalina; Cruttenden Kim; Maggirwar Sanjay B; Gendelman Howard E; Dewhurst Stephen; Gelbard Harris A
Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment.
Journal of neurovirology 2009;15(2):176-86.
2009: Reynolds Ashley D; Stone David K; Mosley R Lee; Gendelman Howard E
Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4137-49.
2009: Liu Jianuo; Gong Nan; Huang Xiuyan; Reynolds Ashley D; Mosley R Lee; Gendelman Howard E
Neuromodulatory activities of CD4+CD25+ regulatory T cells in a murine model of HIV-1-associated neurodegeneration.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3855-65.
2009: Gendelman Howard E; Ding Shengyuan; Gong Nan; Liu Jianuo; Ramirez Servio H; Persidsky Yuri; Mosley R Lee; Wang Tong; Volsky David J; Xiong Huangui
Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2009;4(1):47-59.
2009: Kiyota Tomomi; Yamamoto Masaru; Xiong Huangui; Lambert Mary P; Klein William L; Gendelman Howard E; Ransohoff Richard M; Ikezu Tsuneya
CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction.
PloS one 2009;4(7):e6197.
2009: Kadiu Irena; Wang Tong; Schlautman Joshua D; Dubrovsky Larisa; Ciborowski Pawel; Bukrinsky Michael; Gendelman Howard E
HIV-1 transforms the monocyte plasma membrane proteome.
Cellular immunology 2009;258(1):44-58.
2009: Beduneau Arnaud; Ma Zhiya; Grotepas Cassi B; Kabanov Alexander; Rabinow Barrett E; Gong Nan; Mosley R Lee; Dou Huanyu; Boska Michael D; Gendelman Howard E
Facilitated monocyte-macrophage uptake and tissue distribution of superparmagnetic iron-oxide nanoparticles.
PloS one 2009;4(2):e4343.
2008: Luciano-Montalvo C; Ciborowski P; Duan F; Gendelman H E; Meléndez L M
Proteomic analyses associate cystatin B with restricted HIV-1 replication in placental macrophages.
Placenta 2008;29(12):1016-23.
2008: Wang Tong; Gong Nan; Liu Jianuo; Kadiu Irena; Kraft-Terry Stephanie D; Schlautman Joshua D; Ciborowski Pawel; Volsky David J; Gendelman Howard E
HIV-1-infected astrocytes and the microglial proteome.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2008;3(3):173-86.
2008: Liu Yutong; Uberti Mariano G; Dou Huanyu; Banerjee Rebecca; Grotepas Cassi B; Stone David K; Rabinow Barrett E; Gendelman Howard E; Boska Michael D
Ingress of blood-borne macrophages across the blood-brain barrier in murine HIV-1 encephalitis.
Journal of neuroimmunology 2008;200(1-2):41-52.
2008: Gendelman Howard E
Disseminating research discovery through an interactive video: a paradigm shift for journal publication.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2008;3(2):57.
2008: Gendelman Howard E; Kabanov Alexander; Linder James
The promise and perils of CNS drug delivery: a video debate.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2008;3(2):58.
2008: Reynolds Ashley D; Kadiu Irena; Garg Sanjay K; Glanzer Jason G; Nordgren Tara; Ciborowski Pawel; Banerjee Ruma; Gendelman Howard E
Nitrated alpha-synuclein and microglial neuroregulatory activities.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2008;3(2):59-74.
2008: Reynolds Ashley D; Glanzer Jason G; Kadiu Irena; Ricardo-Dukelow Mary; Chaudhuri Anathbandhu; Ciborowski Pawel; Cerny Ronald; Gelman Benjamin; Thomas Mark P; Mosley R Lee; Gendelman Howard E
Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease.
Journal of neurochemistry 2008;104(6):1504-25.
2008: Chaudhuri Anathbandhu; Yang Bo; Gendelman Howard E; Persidsky Yuri; Kanmogne Georgette D
STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier.
Blood 2008;111(4):2062-72.
2008: Gorantla Santhi; Liu Jianuo; Wang Tong; Holguin Adelina; Sneller Hannah M; Dou Huanyu; Kipnis Jonathan; Poluektova Larisa; Gendelman Howard E
Modulation of innate immunity by copolymer-1 leads to neuroprotection in murine HIV-1 encephalitis.
Glia 2008;56(2):223-32.
2008: Schlautman Joshua D; Rozek Wojciech; Stetler Robert; Mosley R Lee; Gendelman Howard E; Ciborowski Pawel
Multidimensional protein fractionation using ProteomeLab PF 2Dtrade mark for profiling amyotrophic lateral sclerosis immunity: A preliminary report.
Proteome science 2008;6():26.
2008: Banerjee Rebecca; Mosley R Lee; Reynolds Ashley D; Dhar Alok; Jackson-Lewis Vernice; Gordon Paul H; Przedborski Serge; Gendelman Howard E
Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice.
PloS one 2008;3(7):e2740.
2008: Wang Tong; Gong Nan; Liu Jianuo; Kadiu Irena; Kraft-Terry Stephanie D; Mosley R Lee; Volsky David J; Ciborowski Pawel; Gendelman Howard E
Proteomic modeling for HIV-1 infected microglia-astrocyte crosstalk.
PloS one 2008;3(6):e2507.
2008: Benner Eric J; Banerjee Rebecca; Reynolds Ashley D; Sherman Simon; Pisarev Vladimir M; Tsiperson Vladislav; Nemachek Craig; Ciborowski Pawel; Przedborski Serge; Mosley R Lee; Gendelman Howard E
Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons.
PloS one 2008;3(1):e1376.
2007: Laspiur Juliana Pérez; Anderson Eric R; Ciborowski Pawel; Wojna Valerie; Rozek Wojciech; Duan Fenghai; Mayo Raul; Rodríguez Elaine; Plaud-Valentín Marinés; Rodríguez-Orengo José; Gendelman Howard E; Meléndez Loyda M
CSF proteomic fingerprints for HIV-associated cognitive impairment.
Journal of neuroimmunology 2007;192(1-2):157-70.
2007: Ghosh Anamitra; Roy Avik; Liu Xiaojuan; Kordower Jeffrey H; Mufson Elliott J; Hartley Dean M; Ghosh Sankar; Mosley R Lee; Gendelman Howard E; Pahan Kalipada
Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(47):18754-9.
2007: Liu Jianuo; Johnson Thomas V; Lin Jamie; Ramirez Servio H; Bronich Tatiana K; Caplan Steve; Persidsky Yuri; Gendelman Howard E; Kipnis Jonathan
T cell independent mechanism for copolymer-1-induced neuroprotection.
European journal of immunology 2007;37(11):3143-54.
2007: Rozek Wojciech; Ricardo-Dukelow Mary; Holloway Sondra; Gendelman Howard E; Wojna Valerie; Melendez Loyda M; Ciborowski Pawel
Cerebrospinal fluid proteomic profiling of HIV-1-infected patients with cognitive impairment.
Journal of proteome research 2007;6(11):4189-99.
2007: Reynolds Ashley D; Banerjee Rebecca; Liu Jianou; Gendelman Howard E; Mosley R Lee
Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease.
Journal of leukocyte biology 2007;82(5):1083-94.
2007: Gorantla Santhi; Liu Jianou; Sneller Hannah; Dou Huanyu; Holguin Adelina; Smith Lynette; Ikezu Tsuneya; Volsky David J; Poluektova Larisa; Gendelman Howard E
Copolymer-1 induces adaptive immune anti-inflammatory glial and neuroprotective responses in a murine model of HIV-1 encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(7):4345-56.
2007: Batrakova Elena V; Li Shu; Reynolds Ashley D; Mosley R Lee; Bronich Tatiana K; Kabanov Alexander V; Gendelman Howard E
A macrophage-nanozyme delivery system for Parkinson's disease.
Bioconjugate chemistry 2007;18(5):1498-506.
2007: Mosley R Lee; Gordon Paul H; Hasiak Christopher M; Van Wetering Francis J; Mitsumoto Hiroshi; Gendelman Howard E
Glatiramer acetate immunization induces specific antibody and cytokine responses in ALS patients.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2007;8(4):235-42.
2007: Glanzer Jason G; Enose Yoshimi; Wang Tong; Kadiu Irena; Gong Nan; Rozek Wojciech; Liu Jianuo; Schlautman Joshua D; Ciborowski Pawel S; Thomas Mark P; Gendelman Howard E
Genomic and proteomic microglial profiling: pathways for neuroprotective inflammatory responses following nerve fragment clearance and activation.
Journal of neurochemistry 2007;102(3):627-45.
2007: Gendelman Howard E
The Journal of Neuroimmune Pharmacology reaches its stride.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2007;2(2):129-30.
2007: Boska Michael D; Hasan Khader M; Kibuule Danette; Banerjee Rebecca; McIntyre Erin; Nelson Jay A; Hahn Theresa; Gendelman Howard E; Mosley R Lee
Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson's disease.
Neurobiology of disease 2007;26(3):590-6.
2007: Ciborowski Pawel; Kadiu Irena; Rozek Wojciech; Smith Lynette; Bernhardt Kristen; Fladseth Melissa; Ricardo-Dukelow Mary; Gendelman Howard E
Investigating the human immunodeficiency virus type 1-infected monocyte-derived macrophage secretome.
Virology 2007;363(1):198-209.
2007: Kadiu Irena; Ricardo-Dukelow Mary; Ciborowski Pawel; Gendelman Howard E
Cytoskeletal protein transformation in HIV-1-infected macrophage giant cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6404-15.
2007: Spitzenberger Timothy J; Heilman David; Diekmann Casey; Batrakova Elena V; Kabanov Alexander V; Gendelman Howard E; Elmquist William F; Persidsky Yuri
Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(5):1033-42.
2007: Ricardo-Dukelow Mary; Kadiu Irena; Rozek Wojciech; Schlautman Joshua; Persidsky Yuri; Ciborowski Pawel; Kanmogne Georgette D; Gendelman Howard E
HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: new insights into blood-brain barrier dysfunction for HIV-1-associated dementia.
Journal of neuroimmunology 2007;185(1-2):37-46.
2007: Haenggeli Christine; Julien Jean-Pierre; Mosley R Lee; Perez Natalie; Dhar Alok; Gendelman Howard E; Rothstein Jeffrey D
Therapeutic immunization with a glatiramer acetate derivative does not alter survival in G93A and G37R SOD1 mouse models of familial ALS.
Neurobiology of disease 2007;26(1):146-52.
2007: Dewhurst Stephen; Maggirwar Sanjay B; Schifitto Giovanni; Gendelman Howard E; Gelbard Harris A
Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2007;2(1):93-6.
2007: Gendelman Howard E
Biomarkers, laboratory, and animal models for the design and development of adjunctive therapies for HIV-1 dementia and other neuroinflammatory disorders.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2007;2(1):8-13.
2007: Gorantla Santhi; Sneller Hannah; Walters Lisa; Sharp John G; Pirruccello Samuel J; West John T; Wood Charles; Dewhurst Stephen; Gendelman Howard E; Poluektova Larisa
Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice.
Journal of virology 2007;81(6):2700-12.
2007: Yamamoto Masaru; Kiyota Tomomi; Horiba Masahide; Buescher James L; Walsh Shannon M; Gendelman Howard E; Ikezu Tsuneya
Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.
The American journal of pathology 2007;170(2):680-92.
2007: Laurie Chad; Reynolds Ashley; Coskun Ozlem; Bowman Erik; Gendelman Howard E; Mosley R Lee
CD4+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Journal of neuroimmunology 2007;183(1-2):60-8.
2007: Dou Huanyu; Morehead Justin; Destache Christopher J; Kingsley Jeffrey D; Shlyakhtenko Lyudmila; Zhou You; Chaubal Mahesh; Werling Jane; Kipp James; Rabinow Barrett E; Gendelman Howard E
Laboratory investigations for the morphologic, pharmacokinetic, and anti-retroviral properties of indinavir nanoparticles in human monocyte-derived macrophages.
Virology 2007;358(1):148-58.
2007: Thomas Mark P; Chartrand Kathryn; Reynolds Ashley; Vitvitsky Victor; Banerjee Ruma; Gendelman Howard E
Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease.
Journal of neurochemistry 2007;100(2):503-19.
2007: Kanmogne Georgette D; Schall Kathy; Leibhart Jessica; Knipe Bryan; Gendelman Howard E; Persidsky Yuri
HIV-1 gp120 compromises blood-brain barrier integrity and enhances monocyte migration across blood-brain barrier: implication for viral neuropathogenesis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(1):123-34.
2007: Buescher James L; Gross Sara; Gendelman Howard E; Ikezu Tsuneya
The neuropathogenesis of HIV-1 infection.
Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn 2007;85():45-67.
2007: Reynolds Ashley; Laurie Chad; Mosley R Lee; Gendelman Howard E
Oxidative stress and the pathogenesis of neurodegenerative disorders.
International review of neurobiology 2007;82():297-325.
2006: Garg Sanjay; Vitvitsky Victor; Gendelman Howard E; Banerjee Ruma
Monocyte differentiation, activation, and mycobacterial killing are linked to transsulfuration-dependent redox metabolism.
The Journal of biological chemistry 2006;281(50):38712-20.
2006: Vitvitsky Victor; Thomas Mark; Ghorpade Anuja; Gendelman Howard E; Banerjee Ruma
A functional transsulfuration pathway in the brain links to glutathione homeostasis.
The Journal of biological chemistry 2006;281(47):35785-93.
2006: Peng Hui; Erdmann Nathan; Whitney Nicholas; Dou Huangyu; Gorantla Santhi; Gendelman Howard E; Ghorpade Anuja; Zheng Jialin
HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
Glia 2006;54(6):619-29.
2006: Gorantla Santhi; Dou Huanyu; Boska Michael; Destache Chris J; Nelson Jay; Poluektova Larisa; Rabinow Barett E; Gendelman Howard E; Mosley R Lee
Quantitative magnetic resonance and SPECT imaging for macrophage tissue migration and nanoformulated drug delivery.
Journal of leukocyte biology 2006;80(5):1165-74.
2006: Dou Huanyu; Destache Christopher J; Morehead Justin R; Mosley R Lee; Boska Michael D; Kingsley Jeffrey; Gorantla Santhi; Poluektova Larisa; Nelson Jay A; Chaubal Mahesh; Werling Jane; Kipp James; Rabinow Barrett E; Gendelman Howard E
Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery.
Blood 2006;108(8):2827-35.
2006: Kingsley Jeffrey D; Dou Huanyu; Morehead Justin; Rabinow Barrett; Gendelman Howard E; Destache Christopher J
Nanotechnology: a focus on nanoparticles as a drug delivery system.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2006;1(3):340-50.
2006: Crutcher Keith A; Gendelman Howard E; Kipnis Jonathan; Perez-Polo J Regino; Perry V H; Popovich Phillip G; Weaver Lynne C
Debate: "is increasing neuroinflammation beneficial for neural repair?".
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2006;1(3):195-211.
2006: Dou Huanyu; Morehead Justin; Bradley Jennifer; Gorantla Santhi; Ellison Brent; Kingsley Jeff; Smith Lynette M; Chao Wei; Bentsman Galina; Volsky David J; Gendelman Howard E
Neuropathologic and neuroinflammatory activities of HIV-1-infected human astrocytes in murine brain.
Glia 2006;54(2):81-93.
2006: Ciborowski Pawel; Gendelman Howard E
Human immunodeficiency virus-mononuclear phagocyte interactions: emerging avenues of biomarker discovery, modes of viral persistence and disease pathogenesis.
Current HIV research 2006;4(3):279-91.
2006: Schifitto G; Peterson D R; Zhong J; Ni H; Cruttenden K; Gaugh M; Gendelman H E; Boska M; Gelbard H
Valproic acid adjunctive therapy for HIV-associated cognitive impairment: a first report.
Neurology 2006;66(6):919-21.
2005: Poluektova Larisa; Meyer Vakara; Walters Lisa; Paez Ximena; Gendelman Howard E
Macrophage-induced inflammation affects hippocampal plasticity and neuronal development in a murine model of HIV-1 encephalitis.
Glia 2005;52(4):344-53.
2005: Kadiu I; Glanzer J G; Kipnis J; Gendelman H E; Thomas M P
Mononuclear phagocytes in the pathogenesis of neurodegenerative diseases.
Neurotoxicity research 2005;8(1-2):25-50.
2005: Potula Raghava; Poluektova Larisa; Knipe Bryan; Chrastil Jesse; Heilman David; Dou Huanyu; Takikawa Osamu; Munn David H; Gendelman Howard E; Persidsky Yuri
Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis.
Blood 2005;106(7):2382-90.
2005: Dou Huanyu; Ellison Brent; Bradley Jennifer; Kasiyanov Alexander; Poluektova Larisa Y; Xiong Huangui; Maggirwar Sanjay; Dewhurst Stephen; Gelbard Harris A; Gendelman Howard E
Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(37):8375-85.
2005: Enose Yoshimi; Destache Christopher J; Mack Andrea L; Anderson James R; Ullrich Fred; Ciborowski Pawel S; Gendelman Howard E
Proteomic fingerprints distinguish microglia, bone marrow, and spleen macrophage populations.
Glia 2005;51(3):161-72.
2005: Ghorpade Anuja; Bruch Leslie; Persidsky Yuri; Chin Betty; Brown William H C; Borgmann Kathleen; Persidsky Raisa; Wu Li; Holter Spring; Cotter Robin; Faraci Jill; Heilman David; Meyer VaKara; Potter Jane F; Swindells Susan; Gendelman Howard E
Development of a rapid autopsy program for studies of brain immunity.
Journal of neuroimmunology 2005;163(1-2):135-44.
2005: Ghorpade Anuja; Persidsky Yury; Swindells Susan; Borgmann Kathleen; Persidsky Raisa; Holter Spring; Cotter Robin; Gendelman Howard E
Neuroinflammatory responses from microglia recovered from HIV-1-infected and seronegative subjects.
Journal of neuroimmunology 2005;163(1-2):145-56.
2005: Yamamoto Masaru; Horiba Masahide; Buescher James L; Huang DeReng; Gendelman Howard E; Ransohoff Richard M; Ikezu Tsuneya
Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition.
The American journal of pathology 2005;166(5):1475-85.
2005: Nelson J A; Dou H; Ellison B; Uberti M; Xiong H; Anderson E; Mellon M; Gelbard H A; Boska M; Gendelman H E
Coregistration of quantitative proton magnetic resonance spectroscopic imaging with neuropathological and neurophysiological analyses defines the extent of neuronal impairments in murine human immunodeficiency virus type-1 encephalitis.
Journal of neuroscience research 2005;80(4):562-75.
2005: Boska Michael D; Lewis Travis B; Destache Christopher J; Benner Eric J; Nelson Jay A; Uberti Mariano; Mosley R Lee; Gendelman Howard E
Quantitative 1H magnetic resonance spectroscopic imaging determines therapeutic immunization efficacy in an animal model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(7):1691-700.
2005: Gorantla Santhi; Santos Kathlyn; Meyer Vakara; Dewhurst Stephen; Bowers William J; Federoff Howard J; Gendelman Howard E; Poluektova Larisa
Human dendritic cells transduced with herpes simplex virus amplicons encoding human immunodeficiency virus type 1 (HIV-1) gp120 elicit adaptive immune responses from human cells engrafted into NOD/SCID mice and confer partial protection against HIV-1 challenge.
Journal of virology 2005;79(4):2124-32.
2005: Gendelman Howard E; Persidsky Yuri
Infections of the nervous system.
Lancet neurology 2005;4(1):12-3.
2005: Borgmann Kathleen; Gendelman Howard E; Ghorpade Anuja
Isolation and HIV-1 infection of primary human microglia from fetal and adult tissue.
Methods in molecular biology (Clifton, N.J.) 2005;304():49-70.
2005: Gorantla Santhi; Che Myhanh; Gendelman Howard E
Isolation, propagation, and HIV-1 infection of monocyte-derived macrophages and recovery of virus from brain and cerebrospinal fluid.
Methods in molecular biology (Clifton, N.J.) 2005;304():35-48.
2004: Ciborowski Pawel; Enose Yoshimi; Mack Andrea; Fladseth Melissa; Gendelman Howard E
Diminished matrix metalloproteinase 9 secretion in human immunodeficiency virus-infected mononuclear phagocytes: modulation of innate immunity and implications for neurological disease.
Journal of neuroimmunology 2004;157(1-2):11-6.
2004: Anderson Eric R; Gendelman Howard E; Xiong Huangui
Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(32):7194-8.
2004: Benner Eric J; Mosley R Lee; Destache Chris J; Lewis Travis B; Jackson-Lewis Vernice; Gorantla Santhi; Nemachek Craig; Green Steven R; Przedborski Serge; Gendelman Howard E
Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9435-40.
2004: Poluektova Larisa; Gorantla Santhi; Faraci Jill; Birusingh Kevin; Dou Huanyu; Gendelman Howard E
Neuroregulatory events follow adaptive immune-mediated elimination of HIV-1-infected macrophages: studies in a murine model of viral encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7610-7.
2004: Carlson Kimberly A; Limoges Jenae; Pohlman Garrett D; Poluektova Larisa Y; Langford Dianne; Masliah Eliezer; Ikezu Tsuneya; Gendelman Howard E
OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis.
Journal of neuroimmunology 2004;150(1-2):186-98.
2004: Ryan Lisa A; Peng Hui; Erichsen David A; Huang Yunlong; Persidsky Yuri; Zhou You; Gendelman Howard E; Zheng Jialin
TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia.
Journal of neuroimmunology 2004;148(1-2):127-39.
2004: Carlson Kimberly A; Ciborowski Pawel; Schellpeper Courtney N; Biskup Toni M; Shen Rong Fong; Luo Xiaoguang; Destache Christopher J; Gendelman Howard E
Proteomic fingerprinting of HIV-1-infected human monocyte-derived macrophages: a preliminary report.
Journal of neuroimmunology 2004;147(1-2):35-42.
2004: Boska Michael D; Mosley R Lee; Nawab Mehmood; Nelson Jay A; Zelivyanskaya Marina; Poluektova Larisa; Uberti Mariano; Dou Huanyu; Lewis Travis B; Gendelman Howard E
Advances in neuroimaging for HIV-1 associated neurological dysfunction: clues to the diagnosis, pathogenesis and therapeutic monitoring.
Current HIV research 2004;2(1):61-78.
2004: Carlson Kimberly A; Leisman Gary; Limoges Jenae; Pohlman Garrett D; Horiba Masahide; Buescher James; Gendelman Howard E; Ikezu Tsuneya
Molecular characterization of a putative antiretroviral transcriptional factor, OTK18.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):381-91.
2004: Dou Huanyu; Kingsley Jeffrey D; Mosley R Lee; Gelbard Harris A; Gendelman Howard E
Neuroprotective strategies for HIV-1 associated dementia.
Neurotoxicity research 2004;6(7-8):503-21.
2004: Nukuna Adeline; Gendelman Howard E; Limoges Jenae; Rasmussen Jennifer; Poluektova Larisa; Ghorpade Anuja; Persidsky Yuri
Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis.
Journal of neurovirology 2004;10 Suppl 1():82-90.
2004: Wojna Valerie; Carlson Kimberly A; Luo Xiaoguang; Mayo Raúl; Meléndez Loyda M; Kraiselburd Edmundo; Gendelman Howard E
Proteomic fingerprinting of human immunodeficiency virus type 1-associated dementia from patient monocyte-derived macrophages: A case study.
Journal of neurovirology 2004;10 Suppl 1():74-81.
2003: Persidsky Yuri; Gendelman Howard E
Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection.
Journal of leukocyte biology 2003;74(5):691-701.
2003: Dou Huanyu; Birusingh Kevin; Faraci Jill; Gorantla Santhi; Poluektova Larisa Y; Maggirwar Sanjay B; Dewhurst Stephen; Gelbard Harris A; Gendelman Howard E
Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(27):9162-70.
2003: Suryadevara Radhika; Holter Spring; Borgmann Kathleen; Persidsky Raisa; Labenz-Zink Christine; Persidsky Yuri; Gendelman Howard E; Wu Li; Ghorpade Anuja
Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia.
Glia 2003;44(1):47-56.
2003: Shibata Annemarie; Zelivyanskaya Marina; Limoges Jenae; Carlson Kimberly A; Gorantla Santhi; Branecki Chad; Bishu Shrinivas; Xiong Huangui; Gendelman Howard E
Peripheral nerve induces macrophage neurotrophic activities: regulation of neuronal process outgrowth, intracellular signaling and synaptic function.
Journal of neuroimmunology 2003;142(1-2):112-29.
2003: Zelivyanskaya Marina L; Nelson Jay A; Poluektova Larissa; Uberti Mariano; Mellon Melissa; Gendelman Howard E; Boska Michael D
Tracking superparamagnetic iron oxide labeled monocytes in brain by high-field magnetic resonance imaging.
Journal of neuroscience research 2003;73(3):284-95.
2003: Luo X; Carlson K A; Wojna V; Mayo R; Biskup T M; Stoner J; Anderson J; Gendelman H E; Meléndez L M
Macrophage proteomic fingerprinting predicts HIV-1-associated cognitive impairment.
Neurology 2003;60(12):1931-7.
2003: Erichsen David; Lopez Alicia L; Peng Hui; Niemann Douglas; Williams Clancy; Bauer Michael; Morgello Susan; Cotter Robin L; Ryan Lisa A; Ghorpade Anuja; Gendelman Howard E; Zheng Jialin
Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia.
Journal of neuroimmunology 2003;138(1-2):144-55.
2003: Xiong Huangui; McCabe Laura; Skifter Donald; Monaghan Daniel T; Gendelman Howard E
Activation of NR1a/NR2B receptors by monocyte-derived macrophage secretory products: implications for human immunodeficiency virus type one-associated dementia.
Neuroscience letters 2003;341(3):246-50.
2003: Luo Xiaoguang; Weber Gregory A; Zheng Jialin; Gendelman Howard E; Ikezu Tsuneya
C1q-calreticulin induced oxidative neurotoxicity: relevance for the neuropathogenesis of Alzheimer's disease.
Journal of neuroimmunology 2003;135(1-2):62-71.
2003: Xiong Huangui; Boyle Jeffery; Winkelbauer Matthew; Gorantla Santhi; Zheng Jialin; Ghorpade Anuja; Persidsky Yuri; Carlson Kimberly A; Gendelman Howard E
Inhibition of long-term potentiation by interleukin-8: implications for human immunodeficiency virus-1-associated dementia.
Journal of neuroscience research 2003;71(4):600-7.
2003: Anderson E R; Boyle J; Zink W E; Persidsky Y; Gendelman H E; Xiong H
Hippocampal synaptic dysfunction in a murine model of human immunodeficiency virus type 1 encephalitis.
Neuroscience 2003;118(2):359-69.
2002: Persidsky Yuri; Gendelman Howard E
Murine models for human immunodeficiency virus type 1-associated dementia: the development of new treatment testing paradigms.
Journal of neurovirology 2002;8 Suppl 2():49-52.
2002: Gendelman Howard E
Neural immunity: Friend or foe?
Journal of neurovirology 2002;8(6):474-9.
2002: Anderson Eric; Zink Walter; Xiong Huangui; Gendelman Howard E
HIV-1-associated dementia: a metabolic encephalopathy perpetrated by virus-infected and immune-competent mononuclear phagocytes.
Journal of acquired immune deficiency syndromes (1999) 2002;31 Suppl 2():S43-54.
2002: Diesing Thomas S; Swindells Susan; Gelbard Harris; Gendelman Howard E
HIV-1-associated dementia: a basic science and clinical perspective.
The AIDS reader 2002;12(8):358-68.
2002: Poluektova Larisa Y; Munn David H; Persidsky Yuri; Gendelman Howard E
Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3941-9.
2002: Ryan Lisa A; Cotter Robin L; Zink Walter E; Gendelman Howard E; Zheng Jialin
Macrophages, chemokines and neuronal injury in HIV-1-associated dementia.
Cellular and molecular biology (Noisy-le-Grand, France) 2002;48(2):137-50.
2002: Zink Walter E; Anderson Eric; Boyle Jeffrey; Hock Lynette; Rodriguez-Sierra Jorge; Xiong Huangui; Gendelman Howard E; Persidsky Yuri
Impaired spatial cognition and synaptic potentiation in a murine model of human immunodeficiency virus type 1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(6):2096-105.
2002: Chung Induk; Zelivyanskaya Marina; Gendelman Howard E
Mononuclear phagocyte biophysiology influences brain transendothelial and tissue migration: implication for HIV-1-associated dementia.
Journal of neuroimmunology 2002;122(1-2):40-54.
2001: Poluektova L; Moran T; Zelivyanskaya M; Swindells S; Gendelman H E; Persidsky Y
The regulation of alpha chemokines during HIV-1 infection and leukocyte activation: relevance for HIV-1-associated dementia.
Journal of neuroimmunology 2001;120(1-2):112-28.
2001: Zheng J; Thylin M R; Persidsky Y; Williams C E; Cotter R L; Zink W; Ryan L; Ghorpade A; Lewis K; Gendelman H E
HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise.
Neurotoxicity research 2001;3(5):461-84.
2001: Zheng J; Thylin M R; Cotter R L; Lopez A L; Ghorpade A; Persidsky Y; Xiong H; Leisman G B; Che M H; Gendelman H E
HIV-1 infected and immune competent mononuclear phagocytes induce quantitative alterations in neuronal dendritic arbor: relevance for HIV-1-associated dementia.
Neurotoxicity research 2001;3(5):443-59.
2001: Ryan L A; Zheng J; Brester M; Bohac D; Hahn F; Anderson J; Ratanasuwan W; Gendelman H E; Swindells S
Plasma levels of soluble CD14 and tumor necrosis factor-alpha type II receptor correlate with cognitive dysfunction during human immunodeficiency virus type 1 infection.
The Journal of infectious diseases 2001;184(6):699-706.
2001: Ghorpade A; Persidskaia R; Suryadevara R; Che M; Liu X J; Persidsky Y; Gendelman H E
Mononuclear phagocyte differentiation, activation, and viral infection regulate matrix metalloproteinase expression: implications for human immunodeficiency virus type 1-associated dementia.
Journal of virology 2001;75(14):6572-83.
2001: Cotter R L; Zheng J; Che M; Niemann D; Liu Y; He J; Thomas E; Gendelman H E
Regulation of human immunodeficiency virus type 1 infection, beta-chemokine production, and CCR5 expression in CD40L-stimulated macrophages: immune control of viral entry.
Journal of virology 2001;75(9):4308-20.
2001: Persidsky Y; Limoges J; Rasmussen J; Zheng J; Gearing A; Gendelman H E
Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis.
Journal of neuroimmunology 2001;114(1-2):57-68.
2001: Limoges J; Poluektova L; Ratanasuwan W; Rasmussen J; Zelivyanskaya M; McClernon D R; Lanier E R; Gendelman H E; Persidsky Y
The efficacy of potent anti-retroviral drug combinations tested in a murine model of HIV-1 encephalitis.
Virology 2001;281(1):21-34.
2001: Zink W E; Boyle J; Persidsky Y; Xiong H; Gendelman H E
Model systems for assessing cognitive function: implications for HIV-1 infection and drugs of abuse.
Advances in experimental medicine and biology 2001;493():7-27.
2000: Persidsky Y; Zheng J; Miller D; Gendelman H E
Mononuclear phagocytes mediate blood-brain barrier compromise and neuronal injury during HIV-1-associated dementia.
Journal of leukocyte biology 2000;68(3):413-22.
2000: Xiong H; Zeng Y C; Lewis T; Zheng J; Persidsky Y; Gendelman H E
HIV-1 infected mononuclear phagocyte secretory products affect neuronal physiology leading to cellular demise: relevance for HIV-1-associated dementia.
Journal of neurovirology 2000;6 Suppl 1():S14-23.
2000: Tong N; Perry S W; Zhang Q; James H J; Guo H; Brooks A; Bal H; Kinnear S A; Fine S; Epstein L G; Dairaghi D; Schall T J; Gendelman H E; Dewhurst S; Sharer L R; Gelbard H A
Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1333-9.
2000: Limoges J; Persidsky Y; Poluektova L; Rasmussen J; Ratanasuwan W; Zelivyanskaya M; McClernon D R; Lanier E R; Gendelman H E
Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice.
Neurology 2000;54(2):379-89.
1999: Zink W E; Zheng J; Persidsky Y; Poluektova L; Gendelman H E
The neuropathogenesis of HIV-1 infection.
FEMS immunology and medical microbiology 1999;26(3-4):233-41.
1999: Persidsky Y; Ghorpade A; Rasmussen J; Limoges J; Liu X J; Stins M; Fiala M; Way D; Kim K S; Witte M H; Weinand M; Carhart L; Gendelman H E
Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis.
The American journal of pathology 1999;155(5):1599-611.
1999: Xiong H; Zeng Y C; Zheng J; Thylin M; Gendelman H E
Soluble HIV-1 infected macrophage secretory products mediate blockade of long-term potentiation: a mechanism for cognitive dysfunction in HIV-1-associated dementia.
Journal of neurovirology 1999;5(5):519-28.
1999: Zheng J; Ghorpade A; Niemann D; Cotter R L; Thylin M R; Epstein L; Swartz J M; Shepard R B; Liu X; Nukuna A; Gendelman H E
Lymphotropic virions affect chemokine receptor-mediated neural signaling and apoptosis: implications for human immunodeficiency virus type 1-associated dementia.
Journal of virology 1999;73(10):8256-67.
1999: Zheng J; Thylin M R; Ghorpade A; Xiong H; Persidsky Y; Cotter R; Niemann D; Che M; Zeng Y C; Gelbard H A; Shepard R B; Swartz J M; Gendelman H E
Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia.
Journal of neuroimmunology 1999;98(2):185-200.
1999: Al-Omaishi J; Bashir R; Gendelman H E
The cellular immunology of multiple sclerosis.
Journal of leukocyte biology 1999;65(4):444-52.
1999: Cotter R L; Burke W J; Thomas V S; Potter J F; Zheng J; Gendelman H E
Insights into the neurodegenerative process of Alzheimer's disease: a role for mononuclear phagocyte-associated inflammation and neurotoxicity.
Journal of leukocyte biology 1999;65(4):416-27.
1999: Gendelman H E; Folks D G
Innate and acquired immunity in neurodegenerative disorders.
Journal of leukocyte biology 1999;65(4):407-8.
1999: Swindells S; Zheng J; Gendelman H E
HIV-associated dementia: new insights into disease pathogenesis and therapeutic interventions.
AIDS patient care and STDs 1999;13(3):153-63.
1999: Xiong H; Zheng J; Thylin M; Gendelman H E
Unraveling the mechanisms of neurotoxicity in HIV type 1-associated dementia: inhibition of neuronal synaptic transmission by macrophage secretory products.
AIDS research and human retroviruses 1999;15(1):57-63.
1998: Gendelman H E; Zheng J; Coulter C L; Ghorpade A; Che M; Thylin M; Rubocki R; Persidsky Y; Hahn F; Reinhard J; Swindells S
Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia.
The Journal of infectious diseases 1998;178(4):1000-7.
1998: Ghorpade A; Xia M Q; Hyman B T; Persidsky Y; Nukuna A; Bock P; Che M; Limoges J; Gendelman H E; Mackay C R
Role of the beta-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia.
Journal of virology 1998;72(4):3351-61.
1998: Ghorpade A; Nukuna A; Che M; Haggerty S; Persidsky Y; Carter E; Carhart L; Shafer L; Gendelman H E
Human immunodeficiency virus neurotropism: an analysis of viral replication and cytopathicity for divergent strains in monocytes and microglia.
Journal of virology 1998;72(4):3340-50.
1997: Persidsky Y; Buttini M; Limoges J; Bock P; Gendelman H E
An analysis of HIV-1-associated inflammatory products in brain tissue of humans and SCID mice with HIV-1 encephalitis.
Journal of neurovirology 1997;3(6):401-16.
1997: Zheng J; Gendelman H E
The HIV-1 associated dementia complex: a metabolic encephalopathy fueled by viral replication in mononuclear phagocytes.
Current opinion in neurology 1997;10(4):319-25.
1997: Persidsky Y; Gendelman H E
Development of laboratory and animal model systems for HIV-1 encephalitis and its associated dementia.
Journal of leukocyte biology 1997;62(1):100-6.
1997: Krajewski S; James H J; Ross J; Blumberg B M; Epstein L G; Gendelman H E; Gummuluru S; Dewhurst S; Sharer L R; Reed J C; Gelbard H A
Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis.
Neuropathology and applied neurobiology 1997;23(3):242-53.
1997: Limoges J; Persidsky Y; Bock P; Gendelman H E
Dexamethasone therapy worsens the neuropathology of human immunodeficiency virus type 1 encephalitis in SCID mice.
The Journal of infectious diseases 1997;175(6):1368-81.
1997: Persidsky Y; Stins M; Way D; Witte M H; Weinand M; Kim K S; Bock P; Gendelman H E; Fiala M
A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3499-510.
1997: Gendelman H E; Persidsky Y; Ghorpade A; Limoges J; Stins M; Fiala M; Morrisett R
The neuropathogenesis of the AIDS dementia complex.
AIDS (London, England) 1997;11 Suppl A():S35-45.
1996: Persidsky Y; Limoges J; McComb R; Bock P; Baldwin T; Tyor W; Patil A; Nottet H S; Epstein L; Gelbard H; Flanagan E; Reinhard J; Pirruccello S J; Gendelman H E
Human immunodeficiency virus encephalitis in SCID mice.
The American journal of pathology 1996;149(3):1027-53.
1996: Nottet H S; Flanagan E M; Flanagan C R; Gelbard H A; Gendelman H E; Reinhard J F
The regulation of quinolinic acid in human immunodeficiency virus-infected monocytes.
Journal of neurovirology 1996;2(2):111-7.
1996: Swindells S; Baldwin T; Kelly C; Baca-Regen L; Loomis L; Post D; Brichacek B; Stevenson M; Dominguez E A; Reddy R; Klein R; Liao M J; Testa D; McDonald T; Bellanti J; Skurkovich S; Gendelman H E
Regulation and characterization of the interferon-alpha present in patients with advanced human immunodeficiency virus type 1 disease.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1996;16(2):127-37.
1996: Nottet H S; Persidsky Y; Sasseville V G; Nukuna A N; Bock P; Zhai Q H; Sharer L R; McComb R D; Swindells S; Soderland C; Gendelman H E
Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):1284-95.
1996: Schmidtmayerova H; Nottet H S; Nuovo G; Raabe T; Flanagan C R; Dubrovsky L; Gendelman H E; Cerami A; Bukrinsky M; Sherry B
Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):700-4.
1995: Swindells S; McConnell J R; McComb R D; Gendelman H E
Utility of cerebral proton magnetic resonance spectroscopy in differential diagnosis of HIV-related dementia.
Journal of neurovirology 1995;1(3-4):268-74.
1995: Persidsky Y; Nottet H S; Sasseville V G; Epstein L G; Gendelman H E
The development of animal model systems for HIV-1 encephalitis and its associated dementia.
Journal of neurovirology 1995;1(3-4):229-43.
1995: Nottet H S; Gendelman H E
Unraveling the neuroimmune mechanisms for the HIV-1-associated cognitive/motor complex.
Immunology today 1995;16(9):441-8.
1995: Bukrinsky M I; Nottet H S; Schmidtmayerova H; Dubrovsky L; Flanagan C R; Mullins M E; Lipton S A; Gendelman H E
Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease.
The Journal of experimental medicine 1995;181(2):735-45.
1995: Heinzinger N; Baca-Regen L; Stevenson M; Gendelman H E
Efficient synthesis of viral nucleic acids following monocyte infection by HIV-1.
Virology 1995;206(1):731-5.
1994: Baca-Regen L; Heinzinger N; Stevenson M; Gendelman H E
Alpha interferon-induced antiretroviral activities: restriction of viral nucleic acid synthesis and progeny virion production in human immunodeficiency virus type 1-infected monocytes.
Journal of virology 1994;68(11):7559-65.
1994: Gendelman H E; Baldwin T; Baca-Regen L; Swindells S; Loomis L; Skurkovich S
Regulation of HIV1 replication by interferon alpha: from laboratory bench to bedside.
Research in immunology 1994;145(8-9):679-84; discussion 684-5.
1994: Gendelman H E; Lipton S A; Tardieu M; Bukrinsky M I; Nottet H S
The neuropathogenesis of HIV-1 infection.
Journal of leukocyte biology 1994;56(3):389-98.
1994: Gendelman H E; Tardieu M
Macrophages/microglia and the pathophysiology of CNS injuries in AIDS.
Journal of leukocyte biology 1994;56(3):387-8.
1994: Stevenson M; Gendelman H E
Cellular and viral determinants that regulate HIV-1 infection in macrophages.
Journal of leukocyte biology 1994;56(3):278-88.
1994: McConnell J R; Swindells S; Ong C S; Gmeiner W H; Chu W K; Brown D K; Gendelman H E
Prospective utility of cerebral proton magnetic resonance spectroscopy in monitoring HIV infection and its associated neurological impairment.
AIDS research and human retroviruses 1994;10(8):977-82.
1994: Heinzinger N K; Bukinsky M I; Haggerty S A; Ragland A M; Kewalramani V; Lee M A; Gendelman H E; Ratner L; Stevenson M; Emerman M
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7311-5.
1994: Baca L M; Genis P; Kalvakolanu D; Sen G; Meltzer M S; Zhou A; Silverman R; Gendelman H E
Regulation of interferon-alpha-inducible cellular genes in human immunodeficiency virus-infected monocytes.
Journal of leukocyte biology 1994;55(3):299-309.
1994: Gendelman H E; Genis P; Jett M; Zhai Q H; Nottet H S
An experimental model system for HIV-1-induced brain injury.
Advances in neuroimmunology 1994;4(3):189-93.
1994: Turpin J A; Fan S X; Hansen B D; Francis M L; Baca-Regen L M; Gendelman H E; Meltzer M S
Regulation of HIV replication in monocytes by interferon.
Progress in molecular and subcellular biology 1994;14():222-41.
1993: Tyor W R; Power C; Gendelman H E; Markham R B
A model of human immunodeficiency virus encephalitis in scid mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(18):8658-62.
1992: Hansen B D; Nara P L; Maheshwari R K; Sidhu G S; Bernbaum J G; Hoekzema D; Meltzer M S; Gendelman H E
Loss of infectivity by progeny virus from alpha interferon-treated human immunodeficiency virus type 1-infected T cells is associated with defective assembly of envelope gp120.
Journal of virology 1992;66(12):7543-8.
1992: Francis M L; Meltzer M S; Gendelman H E
Interferons in the persistence, pathogenesis, and treatment of HIV infection.
AIDS research and human retroviruses 1992;8(2):199-207.
1992: Gendelman H E; Baca L M; Kubrak C A; Genis P; Burrous S; Friedman R M; Jacobs D; Meltzer M S
Induction of IFN-alpha in peripheral blood mononuclear cells by HIV-infected monocytes. Restricted antiviral activity of the HIV-induced IFN.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(2):422-9.
1992: Gendelman H E; Skillman D R; Meltzer M S
Interferon alpha (IFN)-macrophage interactions in human immunodeficiency virus (HIV) infection: role of IFN in the tempo and progression of HIV disease.
International reviews of immunology 1992;8(1):43-54.
1991: Kalter D C; Gendelman H E; Meltzer M S
Inhibition of human immunodeficiency virus infection in monocytes by monoclonal antibodies against leukocyte adhesion molecules.
Immunology letters 1991;30(2):219-27.
1991: Gendelman H E; Ehrlich G D; Baca L M; Conley S; Ribas J; Kalter D C; Meltzer M S; Poiesz B J; Nara P
The inability of human immunodeficiency virus to infect chimpanzee monocytes can be overcome by serial viral passage in vivo.
Journal of virology 1991;65(7):3853-63.
1991: Gendelman H E; Friedman R M; Joe S; Baca L M; Turpin J A; Dveksler G; Meltzer M S; Dieffenbach C
A selective defect of interferon alpha production in human immunodeficiency virus-infected monocytes.
The Journal of experimental medicine 1991;173(1):277.
1991: Kalter D C; Nakamura M; Turpin J A; Baca L M; Hoover D L; Dieffenbach C; Ralph P; Gendelman H E; Meltzer M S
Enhanced HIV replication in macrophage colony-stimulating factor-treated monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(1):298-306.
1991: Meltzer M S; Baca L; Turpin J A; Kalter D C; Dieffenbach C; Friedman R M; Gendelman H E
Regulation of cytokine and viral gene expression in monocytes infected with the human immunodeficiency virus.
Pathobiology : journal of immunopathology, molecular and cellular biology 1991;59(4):209-13.
1990: Gendelman H E; Friedman R M; Joe S; Baca L M; Turpin J A; Dveksler G; Meltzer M S; Dieffenbach C
A selective defect of interferon alpha production in human immunodeficiency virus-infected monocytes.
The Journal of experimental medicine 1990;172(5):1433-42.
1990: Gendelman H E; Baca L M; Turpin J; Kalter D C; Hansen B; Orenstein J M; Dieffenbach C W; Friedman R M; Meltzer M S
Regulation of HIV replication in infected monocytes by IFN-alpha. Mechanisms for viral restriction.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(8):2669-76.
1990: Meltzer M S; Nakamura M; Hansen B D; Turpin J A; Kalter D C; Gendelman H E
Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease.
AIDS research and human retroviruses 1990;6(8):967-71.
1990: Gendelman H E; Baca L; Turpin J A; Kalter D C; Hansen B D; Orenstein J M; Friedman R M; Meltzer M S
Restriction of HIV replication in infected T cells and monocytes by interferon-alpha.
AIDS research and human retroviruses 1990;6(8):1045-9.
1990: Gomatos P J; Stamatos N M; Gendelman H E; Fowler A; Hoover D L; Kalter D C; Burke D S; Tramont E C; Meltzer M S
Relative inefficiency of soluble recombinant CD4 for inhibition of infection by monocyte-tropic HIV in monocytes and T cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(11):4183-8.
1990: Meltzer M S; Skillman D R; Hoover D L; Hanson B D; Turpin J A; Kalter D C; Gendelman H E
Macrophages and the human immunodeficiency virus.
Immunology today 1990;11(6):217-23.
1990: Gendelman H E; Baca L M; Husayni H; Turpin J A; Skillman D; Kalter D C; Orenstein J M; Hoover D L; Meltzer M S
Macrophage-HIV interaction: viral isolation and target cell tropism.
AIDS (London, England) 1990;4(3):221-8.
1990: Meltzer M S; Skillman D R; Gomatos P J; Kalter D C; Gendelman H E
Role of mononuclear phagocytes in the pathogenesis of human immunodeficiency virus infection.
Annual review of immunology 1990;8():169-94.
1990: Gendelman H E; Baca L M; Turpin J A; Kalter D C; Dieffenbach C; Friedman R M; Meltzer M S
Interactions between interferon and the human immunodeficiency virus.
Journal of experimental pathology 1990;5(2):53-67.
1989: Gendelman H E; Orenstein J M; Baca L M; Weiser B; Burger H; Kalter D C; Meltzer M S
The macrophage in the persistence and pathogenesis of HIV infection.
AIDS (London, England) 1989;3(8):475-95.
1988: Meltzer M S; Gendelman H E
Effects of colony stimulating factors on the interaction of monocytes and the human immunodeficiency virus.
Immunology letters 1988;19(3):193-8.

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