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Howard Gendelman

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Andrea L Martinez-Skinner; JoEllyn M McMillan; Ram S Veerubhotla; Huangui Xiong; Fang Yu; Han Liu; Howard E Gendelman
Functional proteome of macrophage carried nanoformulated antiretroviral therapy demonstrates enhanced particle carrying capacity.
Tomomi Kiyota; Robert A Weir; Gang Zhang; Howard E Gendelman; E Elizabeth Higgins; Mohit Jain
CCL2 affects β-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease.
Marco Cosentino; Howard E Gendelman
The first Insubria autumn school on neuroimmunopharmacology: challenging paradigms beyond boundaries.

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2013: Andrea L Martinez-Skinner; JoEllyn M McMillan; Ram S Veerubhotla; Huangui Xiong; Fang Yu; Han Liu; Howard E Gendelman
Functional proteome of macrophage carried nanoformulated antiretroviral therapy demonstrates enhanced particle carrying capacity.
Journal of proteome research 2013;12(5):2282-94.
2013: Tomomi Kiyota; Robert A Weir; Gang Zhang; Howard E Gendelman; E Elizabeth Higgins; Mohit Jain
CCL2 affects β-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease.
Neurobiology of aging 2013;34(4):1060-8.
2013: Marco Cosentino; Howard E Gendelman
The first Insubria autumn school on neuroimmunopharmacology: challenging paradigms beyond boundaries.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2013;8(1):1-3.
2013: Matthew J Haney; Emily B Harrison; Zhijian He; Shawn D Hingtgen; Alexander V Kabanov; Natalia L Klyachko; Vivek Mahajan; R Lee Mosley; Poornima Suresh; Yuling Zhao; Shaheen Ahmed; Howard E Gendelman; Elena V Batrakova
Specific transfection of inflamed brain by macrophages: a new therapeutic strategy for neurodegenerative diseases.
PloS one 2013;8(4):e61852.
2013: Ari Nowacek; Irena Kadiu; JoEllyn McMillan; Howard E Gendelman
Methods for isolation and identification of nanoparticle-containing subcellular compartments.
Methods in molecular biology (Clifton, N.J.) 2013;991():47-55.
2013: Ari Nowacek; Irena Kadiu; JoEllyn McMillan; Howard E Gendelman
Immunoisolation of nanoparticles containing endocytic vesicles for drug quantitation.
Methods in molecular biology (Clifton, N.J.) 2013;991():41-6.
2012: Howard E Gendelman
Change in evolution.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2012;7(4):715-6.
2012: Jessica A Hutter Saunders; David G Standaert; Diego R Torres-Russotto; Hesham H Ali; Heather E Allen; John M Bertoni; Kathryn M Dempsey; Katherine A Estes; Lisa M Kosloski; Jane L Meza; R Lee Mosley; Daniel L Murman; Pamela M Santamaria; Howard E Gendelman
CD4+ regulatory and effector/memory T cell subsets profile motor dysfunction in Parkinson's disease.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2012;7(4):927-38.
2012: Upal Roy; Nathan Smith; Susan Swindells; Yazen Alnouti; Shantanu Balkundi; Samuel M Cohen; Prasanta Dash; Nagsen Gautum; Santhi Gorantla; Georgette Kanmogne; Andrea Martinez-Skinner; JoEllyn McMillan; Jane Meza; R Lee Mosley; Larisa Poluektova; Howard E Gendelman
Pharmacodynamic and antiretroviral activities of combination nanoformulated antiretrovirals in HIV-1-infected human peripheral blood lymphocyte-reconstituted mice.
The Journal of infectious diseases 2012;206(10):1577-88.
2012: Prasanta K Dash; Harris A Gelbard; Howard E Gendelman; Santhi Gorantla; Joellyn McMillan; Rodney L Mosley; Yazen Alnouti; Shantanu Balkundi; Upal Roy; Larisa Poluektova
Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice.
AIDS (London, England) 2012;26(17):2135-44.
2012: David K Stone; Tomomi Kiyota; R Lee Mosley; Howard E Gendelman
A model of nitric oxide induced α-synuclein misfolding in Parkinson's disease.
Neuroscience letters 2012;523(2):167-73.
2012: Irena Kadiu; prabagaran narayanasamy; Wei Zhang; Prasanta K Dash; Howard E Gendelman
Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(2):744-54.
2012: Howard S Fox; Howard E Gendelman
Commentary: Animal models of neuroAIDS.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2012;7(2):301-5.
2012: Matthew J Haney; Alexander V Kabanov; Irena Kadiu; Georgette D Kanmogne; Natalia L Klyachko; R Lee Mosley; Marina Sokolsky-Papkov; Poornima Suresh; Yuling Zhao; Howard E Gendelman; Elena V Batrakova
Blood-borne macrophage-neural cell interactions hitchhike on endosome networks for cell-based nanozyme brain delivery.
Nanomedicine (London, England) 2012;7(6):815-33.
2012: Santhi Gorantla; Howard E Gendelman; Larisa Poluektova
Can humanized mice reflect the complex pathobiology of HIV-associated neurocognitive disorders?
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2012;7(2):352-62.
2012: Sai P Bathena; Michael D Boska; Adrian A Epstein; Howard E Gendelman; Jiangeng Huang; Yazen Alnouti
Rapid and reliable quantitation of amino acids and myo-inositol in mouse brain by high performance liquid chromatography and tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;893-894():15-20.
2012: Santhi Gorantla; Larisa Poluektova; Howard E Gendelman
Rodent models for HIV-associated neurocognitive disorders.
Trends in neurosciences 2012;35(3):197-208.
2012: Kathleen M Grant; Tricia D LeVan; Ming Li; Scott F Stoltenberg; Sandra M Wells; Gustavo Carlo; Howard E Gendelman; Rick A Bevins
Methamphetamine-associated psychosis.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2012;7(1):113-39.
2012: Jessica A L Hutter-Saunders; Howard E Gendelman; R Lee Mosley
Murine motor and behavior functional evaluations for acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxication.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2012;7(1):279-88.
2012: Avik Roy; Saurav Brahmachari; Howard E Gendelman; Anamitra Ghosh; Arundhati Jana; Xiaojuan Liu; Kalipada Pahan
Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease.
PloS one 2012;7(6):e38113.
2012: Georgette D Kanmogne; Xinming Liu; Joellyn McMillan; Larisa Poluektova; Upal Roy; Sangya Singh; Nathan Smith; You Zhou; Yazen Alnouti; Shantanu Balkundi; Tatiana Bronich; Nagsen Gautam; Santhi Gorantla; Alexander Kabanov; Howard E Gendelman
Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells.
International journal of nanomedicine 2012;7():2373-88.
2012: Gwenael Pottiez; Fang Yu; Nichole A Duarte; Ronald Ellis; Howard S Fox; Howard E Gendelman; Igor Grant; Teena Jagadish; Scott Letendre; Pawel Ciborowski
Plasma proteomic profiling in HIV-1 infected methamphetamine abusers.
PloS one 2012;7(2):e31031.
2012: R Lee Mosley; David K Stone; Jessica A Hutter-Saunders; Howard E Gendelman
Inflammation and adaptive immunity in Parkinson's disease.
Cold Spring Harbor perspectives in medicine 2012;2(1):a009381.
2012: Yutong Liu; Balasrinivasa R Sajja; Mariano Uberti; Howard E Gendelman; Tammy Kielian; Michael D Boska
Landmark optimization using local curvature for point-based nonlinear rodent brain image registration.
International journal of biomedical imaging 2012;2012():635207.
2011: Jessica A L Hutter-Saunders; Rodney Lee Mosley; Howard E Gendelman
Pathways towards an effective immunotherapy for Parkinson's disease.
Expert review of neurotherapeutics 2011;11(12):1703-15.
2011: Howard E Gendelman; Stanley H Appel
Neuroprotective activities of regulatory T cells.
Trends in molecular medicine 2011;17(12):687-8.
2011: Irena Kadiu; Howard E Gendelman
Human immunodeficiency virus type 1 endocytic trafficking through macrophage bridging conduits facilitates spread of infection.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2011;6(4):658-75.
2011: Rafael F Bressani; Howard E Gendelman; Shantanu Balkundi; Joellyn McMillan; Ari S Nowacek; Barrett Rabinow; Sangya Singh; Georgette D Kanmogne
Pharmacotoxicology of monocyte-macrophage nanoformulated antiretroviral drug uptake and carriage.
Nanotoxicology 2011;5(4):592-605.
2011: Matthew J Haney; Sheila Higginbotham; Alexander V Kabanov; Shu Li; R Lee Mosley; Joseph A Vetro; Yuling Zhao; Stephanie L Booth; Howard E Gendelman; Huai-Yun Han; Elena V Batrakova
Cell-mediated transfer of catalase nanoparticles from macrophages to brain endothelial, glial and neuronal cells.
Nanomedicine (London, England) 2011;6(7):1215-30.
2011: Jiangeng Huang; JoEllyn McMillan; Upal Roy; Sai Praneeth R Bathena; Nagsen Gautam; Howard E Gendelman; Yazen Alnouti
UPLC-MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2011;879(23):2332-8.
2011: Irena Kadiu; Joellyn McMillan; Ari Nowacek; Howard E Gendelman
Macrophage endocytic trafficking of antiretroviral nanoparticles.
Nanomedicine (London, England) 2011;6(6):975-94.
2011: Irena Kadiu; Howard E Gendelman
Macrophage bridging conduit trafficking of HIV-1 through the endoplasmic reticulum and Golgi network.
Journal of proteome research 2011;10(7):3225-38.
2011: Stephanie D Kraft-Terry; Ian L Engebretsen; Dhundy K Bastola; Howard S Fox; Pawel Ciborowski; Howard E Gendelman
Pulsed stable isotope labeling of amino acids in cell culture uncovers the dynamic interactions between HIV-1 and the monocyte-derived macrophage.
Journal of proteome research 2011;10(6):2852-62.
2011: J A L Hutter-Saunders; L M Kosloski; JoEllyn M McMillan; N Yotam; T Rinat; R Lee Mosley; Howard E Gendelman
BL-1023 improves behavior and neuronal survival in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-intoxicated mice.
Neuroscience 2011;180():293-304.
2011: Elena V Batrakova; Howard E Gendelman; Alexander Kabanov
Cell-mediated drug delivery.
Expert opinion on drug delivery 2011;8(4):415-33.
2011: Ari S Nowacek; Shantanu Balkundi; JoEllyn McMillan; Upal Roy; Andrea Martinez-Skinner; R Lee Mosley; Georgette Kanmogne; Alexander Kabanov; Tatiana Bronich; Howard E Gendelman
Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages.
Journal of controlled release : official journal of the Controlled Release Society 2011;150(2):204-11.
2011: Prasanta K Dash; Santhi Gorantla; Howard E Gendelman; Jaclyn Knibbe; George P Casale; Edward Makarov; Adrian A Epstein; Harris A Gelbard; Michael D Boska; Larisa Y Poluektova
Loss of neuronal integrity during progressive HIV-1 infection of humanized mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(9):3148-57.
2011: Shantanu Balkundi; Tatiana Bronich; Han Chen; Alexander V Kabanov; Georgette Kanmogne; Xinming Liu; Andrea Martinez-Skinner; JoEllyn McMillan; R Lee Mosley; Ari S Nowacek; Upal Roy; Ram S Veerubhotla; Howard E Gendelman
Comparative manufacture and cell-based delivery of antiretroviral nanoformulations.
International journal of nanomedicine 2011;6():3393-404.
2011: JoEllyn McMillan; Elena Batrakova; Howard E Gendelman
Cell delivery of therapeutic nanoparticles.
Progress in molecular biology and translational science 2011;104():563-601.
2011: Stephanie D Kraft-Terry; Howard E Gendelman
Proteomic biosignatures for monocyte-macrophage differentiation.
Cellular immunology 2011;271(2):239-55.
2011: Yuling Zhao; Matthew J Haney; Natalia L Klyachko; Shu Li; Stephanie L Booth; Sheila Higginbotham; Jocelyn Jones; Matthew C Zimmerman; R Lee Mosley; Alexander Kabanov; Howard E Gendelman; Elena V Batrakova
Polyelectrolyte complex optimization for macrophage delivery of redox enzyme nanoparticles.
Nanomedicine (London, England) 2011;6(1):25-42.
2011: Nan Gong; Jianuo Liu; Ashley D Reynolds; Santhi Gorantla; R Lee Mosley; Howard E Gendelman
Brain ingress of regulatory T cells in a murine model of HIV-1 encephalitis.
Journal of neuroimmunology 2011;230(1-2):33-41.
2010: Xiuyan Huang; David K Stone; Fang Yu; Yaoying Zeng; Howard E Gendelman
Functional proteomic analysis for regulatory T cell surveillance of the HIV-1-infected macrophage.
Journal of proteome research 2010;9(12):6759-73.
2010: Santhi Gorantla; Edward Makarov; Jennifer Finke-Dwyer; Antonio Castanedo; Adelina Holguin; Catherine L Gebhart; Howard E Gendelman; Larisa Poluektova
Links between progressive HIV-1 infection of humanized mice and viral neuropathogenesis.
The American journal of pathology 2010;177(6):2938-49.
2010: Ari S Nowacek; JoEllyn McMillan; Reagan Miller; Alec Anderson; Barrett Rabinow; Howard E Gendelman
Nanoformulated antiretroviral drug combinations extend drug release and antiretroviral responses in HIV-1-infected macrophages: implications for neuroAIDS therapeutics.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2010;5(4):592-601.
2010: Harris A Gelbard; Stephen Dewhurst; Sanjay B Maggirwar; Michelle Kiebala; Oksana Polesskaya; Howard E Gendelman
Rebuilding synaptic architecture in HIV-1 associated neurocognitive disease: a therapeutic strategy based on modulation of mixed lineage kinase.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2010;7(4):392-8.
2010: Jayme L Wiederin; Robert M Donahoe; James Robert Anderson; Fang Yu; Howard S Fox; Howard E Gendelman; Pawel S Ciborowski
Plasma proteomic analysis of simian immunodeficiency virus infection of rhesus macaques.
Journal of proteome research 2010;9(9):4721-31.
2010: Stephanie Kraft-Terry; Yamil Gerena; Valerie Wojna; Marines Plaud-Valentin; Yolanda Rodriguez; Pawel Ciborowski; Raul Mayo; Richard L Skolasky; Howard E Gendelman; Loyda M Meléndez
Proteomic analyses of monocytes obtained from Hispanic women with HIV-associated dementia show depressed antioxidants.
Proteomics. Clinical applications 2010;4(8-9):706-14.
2010: Santhi Gorantla; Edward Makarov; Deepa Roy; Jennifer Finke-Dwyer; Leonard Murrin; Howard E Gendelman; Larisa Poluektova
Immunoregulation of a CB2 receptor agonist in a murine model of neuroAIDS.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2010;5(3):456-68.
2010: Lisa M Kosloski; Duy M Ha; Jessica A L Hutter; David K Stone; Michael R Pichler; Ashley D Reynolds; Howard E Gendelman; R Lee Mosley
Adaptive immune regulation of glial homeostasis as an immunization strategy for neurodegenerative diseases.
Journal of neurochemistry 2010;114(5):1261-76.
2010: Tomomi Kiyota; Satoshi Okuyama; Russell J Swan; Michael T Jacobsen; Howard E Gendelman; Tsuneya Ikezu
CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(8):3093-102.
2010: Santhi Gorantla; Edward Makarov; Jennifer Finke-Dwyer; Catherine L Gebhart; William Domm; Stephen Dewhurst; Howard E Gendelman; Larisa Poluektova
CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(12):7082-91.
2010: Honghong Yao; Yanjing Yang; Kee Jun Kim; Crystal Bethel-Brown; Nan Gong; Keiko Funa; Howard E Gendelman; Tsung-Ping Su; John Q Wang; Shilpa Buch
Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration.
Blood 2010;115(23):4951-62.
2010: Elena V Batrakova; Shu Li; Anna M Brynskikh; Amit K Sharma; Yili Li; Michael D Boska; Nan Gong; R Lee Mosley; Valery Alakhov; Howard E Gendelman; Alexander Kabanov
Effects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers.
Journal of controlled release : official journal of the Controlled Release Society 2010;143(3):290-301.
2010: Anna M Brynskikh; Yuling Zhao; R Lee Mosley; Shu Li; Michael D Boska; Natalia L Klyachko; Alexander Kabanov; Howard E Gendelman; Elena V Batrakova
Macrophage delivery of therapeutic nanozymes in a murine model of Parkinson's disease.
Nanomedicine (London, England) 2010;5(3):379-96.
2010: Ashley D Reynolds; David Stone; Jessica A L Hutter; Eric J Benner; R Lee Mosley; Howard E Gendelman
Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(5):2261-71.
2010: R Lee Mosley; Howard E Gendelman
Control of neuroinflammation as a therapeutic strategy for amyotrophic lateral sclerosis and other neurodegenerative disorders.
Experimental neurology 2010;222(1):1-5.
2010: Stephanie D Kraft-Terry; Andrew R Stothert; Shilpa Buch; Howard E Gendelman
HIV-1 neuroimmunity in the era of antiretroviral therapy.
Neurobiology of disease 2010;37(3):542-8.
2010: Dawn Eggert; Prasanta K Dash; Santhi Gorantla; Huanyu Dou; Giovanni Schifitto; Sanjay B Maggirwar; Stephen Dewhurst; Larisa Poluektova; Harris A Gelbard; Howard E Gendelman
Neuroprotective activities of CEP-1347 in models of neuroAIDS.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(2):746-56.
2010: Michael Boska; Yutong Liu; Mariano Uberti; Balarininvasa R Sajja; Shantanu Balkundi; Joellyn McMillan; Howard E Gendelman
Registered bioimaging of nanomaterials for diagnostic and therapeutic monitoring.
Journal of visualized experiments : JoVE 2010;(46):.
2010: Shantanu Balkundi; Ari S Nowacek; Upal Roy; Andrea Martinez-Skinner; Joellyn McMillan; Howard E Gendelman
Methods development for blood borne macrophage carriage of nanoformulated antiretroviral drugs.
Journal of visualized experiments : JoVE 2010;(46):.
2009: Ari S Nowacek; Reagan L Miller; Joellyn McMillan; Georgette Kanmogne; Michel Kanmogne; R Lee Mosley; Zhiya Ma; Sabine Graham; Mahesh Chaubal; Jane Werling; Barrett Rabinow; Huanyu Dou; Howard E Gendelman
NanoART synthesis, characterization, uptake, release and toxicology for human monocyte-macrophage drug delivery.
Nanomedicine (London, England) 2009;4(8):903-17.
2009: Anamitra Ghosh; Avik Roy; Joanna Matras; Saurav Brahmachari; Howard E Gendelman; Kalipada Pahan
Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(43):13543-56.
2009: Stephanie D Kraft-Terry; Shilpa J Buch; Howard S Fox; Howard E Gendelman
A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection.
Neuron 2009;64(1):133-45.
2009: James P Keblesh; Huanyu Dou; Howard E Gendelman; Huangui Xiong
4-Aminopyridine improves spatial memory in a murine model of HIV-1 encephalitis.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2009;4(3):317-27.
2009: Jeymohan Joseph; David Clifford; Steven D Douglas; Howard Fox; Howard E Gendelman; Francisco Gonzalez-Scarano; Igor Grant; Eugene Major; justin charles mcarthur
Planning Future Strategies for Domestic and International NeuroAIDS Research, July 24-25, 2008.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2009;4(3):283-97.
2009: David Stone; Ashley D Reynolds; R Lee Mosley; Howard E Gendelman
Innate and adaptive immunity for the pathobiology of Parkinson's disease.
Antioxidants & redox signaling 2009;11(9):2151-66.
2009: Dawn Eggert; Prasanta K Dash; Nawal Serradji; Chang-Zhi Dong; Pascal Clayette; Francoise Heymans; Huanyu Dou; Santhi Gorantla; Harris A Gelbard; Larisa Poluektova; Howard E Gendelman
Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders.
Journal of neuroimmunology 2009;213(1-2):47-59.
2009: Ari Nowacek; Howard E Gendelman
NanoART, neuroAIDS and CNS drug delivery.
Nanomedicine (London, England) 2009;4(5):557-74.
2009: Ari Nowacek; Lisa M Kosloski; Howard E Gendelman
Neurodegenerative disorders and nanoformulated drug development.
Nanomedicine (London, England) 2009;4(5):541-55.
2009: Huanyu Dou; Cassi B Grotepas; JoEllyn M McMillan; Christopher J Destache; Mahesh Chaubal; Jane Werling; James Kipp; Barrett Rabinow; Howard E Gendelman
Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):661-9.
2009: Ashley D Reynolds; David Stone; R Lee Mosley; Howard E Gendelman
Proteomic studies of nitrated alpha-synuclein microglia regulation by CD4+CD25+ T cells.
Journal of proteome research 2009;8(7):3497-511.
2009: Xiuyan Huang; Ashley D Reynolds; R Lee Mosley; Howard E Gendelman
CD 4+ T cells in the pathobiology of neurodegenerative disorders.
Journal of neuroimmunology 2009;211(1-2):3-15.
2009: Tomomi Kiyota; Masaru Yamamoto; Bryce Schroder; Michael T Jacobsen; Russell J Swan; Mary P Lambert; William L Klein; Howard E Gendelman; Richard M Ransohoff; Tsuneya Ikezu
AAV1/2-mediated CNS gene delivery of dominant-negative CCL2 mutant suppresses gliosis, beta-amyloidosis, and learning impairment of APP/PS1 mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(5):803-9.
2009: Giovanni Schifitto; Jianhui Zhong; David Gill; Derick R Peterson; Michelle D Gaugh; Tong Zhu; Madalina Tivarus; Kim Cruttenden; Sanjay B Maggirwar; Howard E Gendelman; Stephen Dewhurst; Harris A Gelbard
Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment.
Journal of neurovirology 2009;15(2):176-86.
2009: Ashley D Reynolds; David Stone; R Lee Mosley; Howard E Gendelman
Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4137-49.
2009: Jianuo Liu; Nan Gong; Xiuyan Huang; Ashley D Reynolds; R Lee Mosley; Howard E Gendelman
Neuromodulatory activities of CD4+CD25+ regulatory T cells in a murine model of HIV-1-associated neurodegeneration.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(6):3855-65.
2009: Howard E Gendelman; Shengyuan Ding; Nan Gong; Jianuo Liu; Servio Ramirez; Yuri Persidsky; R Lee Mosley; Tong Wang; David J Volsky; Huangui Xiong
Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2009;4(1):47-59.
2009: Tomomi Kiyota; Masaru Yamamoto; Huangui Xiong; Mary P Lambert; William L Klein; Howard E Gendelman; Richard M Ransohoff; Tsuneya Ikezu
CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction.
PloS one 2009;4(7):e6197.
2009: Irena Kadiu; Tong Wang; Joshua D Schlautman; Larisa Dubrovsky; Pawel Ciborowski; Michael Bukrinsky; Howard E Gendelman
HIV-1 transforms the monocyte plasma membrane proteome.
Cellular immunology 2009;258(1):44-58.
2009: Arnaud Beduneau; Zhiya Ma; Cassi B Grotepas; Alexander Kabanov; Barrett Rabinow; Nan Gong; R Lee Mosley; Huanyu Dou; Michael D Boska; Howard E Gendelman
Facilitated monocyte-macrophage uptake and tissue distribution of superparmagnetic iron-oxide nanoparticles.
PloS one 2009;4(2):e4343.
2008: C Luciano-Montalvo; Pawel Ciborowski; F Duan; Howard E Gendelman; Loyda M Meléndez
Proteomic analyses associate cystatin B with restricted HIV-1 replication in placental macrophages.
Placenta 2008;29(12):1016-23.
2008: Tong Wang; Nan Gong; Jianuo Liu; Irena Kadiu; Stephanie D Kraft-Terry; Joshua D Schlautman; Pawel Ciborowski; David J Volsky; Howard E Gendelman
HIV-1-infected astrocytes and the microglial proteome.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2008;3(3):173-86.
2008: Yutong Liu; Mariano G Uberti; Huanyu Dou; Rebecca Banerjee; Cassi B Grotepas; David Stone; Barrett Rabinow; Howard E Gendelman; Michael D Boska
Ingress of blood-borne macrophages across the blood-brain barrier in murine HIV-1 encephalitis.
Journal of neuroimmunology 2008;200(1-2):41-52.
2008: Howard E Gendelman
Disseminating research discovery through an interactive video: a paradigm shift for journal publication.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2008;3(2):57.
2008: Howard E Gendelman; Alexander Kabanov; James Linder
The promise and perils of CNS drug delivery: a video debate.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2008;3(2):58.
2008: Ashley D Reynolds; Irena Kadiu; Sanjay Garg; Jason G Glanzer; Tara Nordgren; Pawel Ciborowski; Ruma Banerjee; Howard E Gendelman
Nitrated alpha-synuclein and microglial neuroregulatory activities.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2008;3(2):59-74.
2008: Ashley D Reynolds; Jason G Glanzer; Irena Kadiu; Mary Ricardo-Dukelow; Anathbandhu Chaudhuri; Pawel Ciborowski; Ronald L Cerny; Benjamin Gelman; Mark P Thomas; R Lee Mosley; Howard E Gendelman
Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease.
Journal of neurochemistry 2008;104(6):1504-25.
2008: Anathbandhu Chaudhuri; Bo Yang; Howard E Gendelman; Yuri Persidsky; Georgette D Kanmogne
STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier.
Blood 2008;111(4):2062-72.
2008: Santhi Gorantla; Jianuo Liu; Tong Wang; Adelina Holguin; Hannah Sneller; Huanyu Dou; Jonathan Kipnis; Larisa Poluektova; Howard E Gendelman
Modulation of innate immunity by copolymer-1 leads to neuroprotection in murine HIV-1 encephalitis.
Glia 2008;56(2):223-32.
2008: Joshua D Schlautman; Wojciech Rozek; Robert Stetler; R Lee Mosley; Howard E Gendelman; Pawel Ciborowski
Multidimensional protein fractionation using ProteomeLab PF 2D for profiling amyotrophic lateral sclerosis immunity: A preliminary report.
Proteome science 2008;6():26.
2008: Rebecca Banerjee; R Lee Mosley; Ashley D Reynolds; Alok Dhar; Vernice Jackson-Lewis; Paul H Gordon; Serge Przedborski; Howard E Gendelman
Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice.
PloS one 2008;3(7):e2740.
2008: Tong Wang; Nan Gong; Jianuo Liu; Irena Kadiu; Stephanie D Kraft-Terry; R Lee Mosley; David J Volsky; Pawel Ciborowski; Howard E Gendelman
Proteomic modeling for HIV-1 infected microglia-astrocyte crosstalk.
PloS one 2008;3(6):e2507.
2008: Eric J Benner; Rebecca Banerjee; Ashley D Reynolds; Simon Sherman; Vladimir Pisarev; Vladislav Tsiperson; Craig Nemachek; Pawel Ciborowski; Serge Przedborski; R Lee Mosley; Howard E Gendelman
Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons.
PloS one 2008;3(1):e1376.
2007: Juliana Pérez Laspiur; Eric R Anderson; Pawel Ciborowski; Valerie Wojna; Wojciech Rozek; Fenghai Duan; Raul Mayo; Elaine Rodríguez; Marinés Plaud-Valentín; José F Rodríguez-Orengo; Howard E Gendelman; Loyda M Meléndez
CSF proteomic fingerprints for HIV-associated cognitive impairment.
Journal of neuroimmunology 2007;192(1-2):157-70.
2007: Anamitra Ghosh; Avik Roy; Xiaojuan Liu; Jeffrey Kordower; Elliott J Mufson; Dean Hartley; Sankar Ghosh; R Lee Mosley; Howard E Gendelman; Kalipada Pahan
Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(47):18754-9.
2007: Jianuo Liu; Thomas Johnson; Jamie Lin; Servio Ramirez; Tatiana K Bronich; Steve Caplan; Yuri Persidsky; Howard E Gendelman; Jonathan Kipnis
T cell independent mechanism for copolymer-1-induced neuroprotection.
European journal of immunology 2007;37(11):3143-54.
2007: Wojciech Rozek; Mary Ricardo-Dukelow; Sondra Holloway; Howard E Gendelman; Valerie Wojna; Loyda Melendez; Pawel Ciborowski
Cerebrospinal fluid proteomic profiling of HIV-1-infected patients with cognitive impairment.
Journal of proteome research 2007;6(11):4189-99.
2007: Ashley D Reynolds; Rebecca Banerjee; Jianou Liu; Howard E Gendelman; R Lee Mosley
Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease.
Journal of leukocyte biology 2007;82(5):1083-94.
2007: Santhi Gorantla; Jianou Liu; Hannah Sneller; Huanyu Dou; Adelina Holguin; Lynette Smith; Tsuneya Ikezu; David J Volsky; Larisa Poluektova; Howard E Gendelman
Copolymer-1 induces adaptive immune anti-inflammatory glial and neuroprotective responses in a murine model of HIV-1 encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(7):4345-56.
2007: Elena V Batrakova; Shu Li; Ashley D Reynolds; R Lee Mosley; Tatiana K Bronich; Alexander Kabanov; Howard E Gendelman
A macrophage-nanozyme delivery system for Parkinson's disease.
Bioconjugate chemistry 2007;18(5):1498-506.
2007: R Lee Mosley; Paul H Gordon; Christopher M Hasiak; Francis J Van Wetering; Hiroshi Mitsumoto; Howard E Gendelman
Glatiramer acetate immunization induces specific antibody and cytokine responses in ALS patients.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2007;8(4):235-42.
2007: Jason G Glanzer; Yoshimi Enose; Tong Wang; Irena Kadiu; Nan Gong; Wojciech Rozek; Jianuo Liu; Joshua D Schlautman; Pawel Ciborowski; Mark P Thomas; Howard E Gendelman
Genomic and proteomic microglial profiling: pathways for neuroprotective inflammatory responses following nerve fragment clearance and activation.
Journal of neurochemistry 2007;102(3):627-45.
2007: Pawel Ciborowski; Irena Kadiu; Wojciech Rozek; Lynette Smith; Kristen Bernhardt; Melissa Fladseth; Mary Ricardo-Dukelow; Howard E Gendelman
Investigating the human immunodeficiency virus type 1-infected monocyte-derived macrophage secretome.
Virology 2007;363(1):198-209.
2007: Howard E Gendelman
The Journal of Neuroimmune Pharmacology reaches its stride.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2007;2(2):129-30.
2007: Michael D Boska; Khader M Hasan; Danette Kibuule; Rebecca Banerjee; Erin McIntyre; Jay A Nelson; Theresa Hahn; Howard E Gendelman; R Lee Mosley
Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson's disease.
Neurobiology of disease 2007;26(3):590-6.
2007: Irena Kadiu; Mary Ricardo-Dukelow; Pawel Ciborowski; Howard E Gendelman
Cytoskeletal protein transformation in HIV-1-infected macrophage giant cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6404-15.
2007: Timothy J Spitzenberger; David Heilman; Casey Diekmann; Elena V Batrakova; Alexander Kabanov; Howard E Gendelman; William F Elmquist; Yuri Persidsky
Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(5):1033-42.
2007: Mary Ricardo-Dukelow; Irena Kadiu; Wojciech Rozek; Joshua Schlautman; Yuri Persidsky; Pawel Ciborowski; Georgette D Kanmogne; Howard E Gendelman
HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: new insights into blood-brain barrier dysfunction for HIV-1-associated dementia.
Journal of neuroimmunology 2007;185(1-2):37-46.
2007: Christine Haenggeli; Jean-Pierre Julien; R Lee Mosley; Natalie Perez; Alok Dhar; Howard E Gendelman; Jeffrey rothstein
Therapeutic immunization with a glatiramer acetate derivative does not alter survival in G93A and G37R SOD1 mouse models of familial ALS.
Neurobiology of disease 2007;26(1):146-52.
2007: Stephen Dewhurst; Sanjay B Maggirwar; Giovanni Schifitto; Howard E Gendelman; Harris A Gelbard
Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2007;2(1):93-6.
2007: Howard E Gendelman
Biomarkers, laboratory, and animal models for the design and development of adjunctive therapies for HIV-1 dementia and other neuroinflammatory disorders.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2007;2(1):8-13.
2007: Santhi Gorantla; Hannah Sneller; Lisa Walters; J Graham Sharp; Samuel J Pirruccello; John T West; Charles Wood; Stephen Dewhurst; Howard E Gendelman; Larisa Poluektova
Human immunodeficiency virus type 1 pathobiology studied in humanized BALB/c-Rag2-/-gammac-/- mice.
Journal of virology 2007;81(6):2700-12.
2007: Huanyu Dou; Justin Morehead; Christopher J Destache; Jeffrey D Kingsley; Luda S Shlyakhtenko; You Zhou; Mahesh Chaubal; Jane Werling; James Kipp; Barrett Rabinow; Howard E Gendelman
Laboratory investigations for the morphologic, pharmacokinetic, and anti-retroviral properties of indinavir nanoparticles in human monocyte-derived macrophages.
Virology 2007;358(1):148-58.
2007: Masaru Yamamoto; Tomomi Kiyota; Masahide Horiba; James L Buescher; Shannon M Walsh; Howard E Gendelman; Tsuneya Ikezu
Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.
The American journal of pathology 2007;170(2):680-92.
2007: Chad Laurie; Ashley Reynolds; Ozlem Coskun; Erik Bowman; Howard E Gendelman; R Lee Mosley
CD4+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
Journal of neuroimmunology 2007;183(1-2):60-8.
2007: James L Buescher; Sara Gross; Howard E Gendelman; Tsuneya Ikezu
The neuropathogenesis of HIV-1 infection.
Handbook of clinical neurology 2007;85():45-67.
2007: Ashley Reynolds; Chad Laurie; R Lee Mosley; Howard E Gendelman
Oxidative stress and the pathogenesis of neurodegenerative disorders.
International review of neurobiology 2007;82():297-325.
2007: Mark P Thomas; Kathryn Chartrand; Ashley Reynolds; Victor M Vitvitsky; Ruma Banerjee; Howard E Gendelman
Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease.
Journal of neurochemistry 2007;100(2):503-19.
2007: Georgette D Kanmogne; Kathy Schall; Jessica Leibhart; Bryan Knipe; Howard E Gendelman; Yuri Persidsky
HIV-1 gp120 compromises blood-brain barrier integrity and enhances monocyte migration across blood-brain barrier: implication for viral neuropathogenesis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(1):123-34.
2006: Sanjay Garg; Victor M Vitvitsky; Howard E Gendelman; Ruma Banerjee
Monocyte differentiation, activation, and mycobacterial killing are linked to transsulfuration-dependent redox metabolism.
The Journal of biological chemistry 2006;281(50):38712-20.
2006: Victor M Vitvitsky; Mark Thomas; Anuja Ghorpade; Howard E Gendelman; Ruma Banerjee
A functional transsulfuration pathway in the brain links to glutathione homeostasis.
The Journal of biological chemistry 2006;281(47):35785-93.
2006: Hui Peng; Nathan Erdmann; Nicholas Whitney; Huanyu Dou; Santhi Gorantla; Howard E Gendelman; Anuja Ghorpade; Jialin Charles Zheng
HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
Glia 2006;54(6):619-29.
2006: Santhi Gorantla; Huanyu Dou; Michael D Boska; Christopher J Destache; Jay Nelson; Larisa Poluektova; Barrett Rabinow; Howard E Gendelman; R Lee Mosley
Quantitative magnetic resonance and SPECT imaging for macrophage tissue migration and nanoformulated drug delivery.
Journal of leukocyte biology 2006;80(5):1165-74.
2006: Huanyu Dou; Christopher J Destache; Justin Morehead; R Lee Mosley; Michael D Boska; Jeffrey D Kingsley; Santhi Gorantla; Larisa Poluektova; Jay A Nelson; Mahesh Chaubal; Jane Werling; James Kipp; Barrett Rabinow; Howard E Gendelman
Development of a macrophage-based nanoparticle platform for antiretroviral drug delivery.
Blood 2006;108(8):2827-35.
2006: Jeffrey D Kingsley; Huanyu Dou; Justin Morehead; Barrett Rabinow; Howard E Gendelman; Christopher J Destache
Nanotechnology: a focus on nanoparticles as a drug delivery system.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2006;1(3):340-50.
2006: keith crutcher; Howard E Gendelman; Jonathan Kipnis; J Regino Perez-Polo; V H Perry; Phillip Popovich; Lynne C Weaver
Debate: "is increasing neuroinflammation beneficial for neural repair?".
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2006;1(3):195-211.
2006: Huanyu Dou; Justin Morehead; Jennifer Bradley; Santhi Gorantla; Brent Ellison; Jeffrey D Kingsley; Lynette M Smith; Wei Chao; Galina Bentsman; David J Volsky; Howard E Gendelman
Neuropathologic and neuroinflammatory activities of HIV-1-infected human astrocytes in murine brain.
Glia 2006;54(2):81-93.
2006: Pawel Ciborowski; Howard E Gendelman
Human immunodeficiency virus-mononuclear phagocyte interactions: emerging avenues of biomarker discovery, modes of viral persistence and disease pathogenesis.
Current HIV research 2006;4(3):279-91.
2006: Giovanni Schifitto; Derick R Peterson; J Zhong; H Ni; Kim A Cruttenden; M Gaugh; Howard E Gendelman; Michael D Boska; Harris A Gelbard
Valproic acid adjunctive therapy for HIV-associated cognitive impairment: a first report.
Neurology 2006;66(6):919-21.
2005: Larisa Poluektova; Vakara Meyer; Lisa Walters; Ximena Paez; Howard E Gendelman
Macrophage-induced inflammation affects hippocampal plasticity and neuronal development in a murine model of HIV-1 encephalitis.
Glia 2005;52(4):344-53.
2005: Irena Kadiu; Jason G Glanzer; Jonathan Kipnis; Howard E Gendelman; Mark P Thomas
Mononuclear phagocytes in the pathogenesis of neurodegenerative diseases.
Neurotoxicity research 2005;8(1-2):25-50.
2005: Raghava Potula; Larisa Poluektova; Bryan Knipe; Jesse Chrastil; David Heilman; Huanyu Dou; Osamu Takikawa; David H Munn; Howard E Gendelman; Yuri Persidsky
Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis.
Blood 2005;106(7):2382-90.
2005: Huanyu Dou; Brent Ellison; Jennifer Bradley; Alexander Kasiyanov; Larisa Poluektova; Huangui Xiong; Sanjay B Maggirwar; Stephen Dewhurst; Harris A Gelbard; Howard E Gendelman
Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(37):8375-85.
2005: Yoshimi Enose; Christopher J Destache; Andrea L Mack; James Robert Anderson; Fred A Ullrich; Pawel Ciborowski; Howard E Gendelman
Proteomic fingerprints distinguish microglia, bone marrow, and spleen macrophage populations.
Glia 2005;51(3):161-72.
2005: Anuja Ghorpade; Leslie Bruch; Yuri Persidsky; Betty Chin; William H C Brown; Kathleen Borgmann; Raisa Persidsky; Li Wu; Spring Holter; Robin Cotter; Jill Faraci; David Heilman; Vakara Meyer; Jane Potter; Susan Swindells; Howard E Gendelman
Development of a rapid autopsy program for studies of brain immunity.
Journal of neuroimmunology 2005;163(1-2):135-44.
2005: Anuja Ghorpade; Yuri Persidsky; Susan Swindells; Kathleen Borgmann; Raisa Persidsky; Spring Holter; Robin Cotter; Howard E Gendelman
Neuroinflammatory responses from microglia recovered from HIV-1-infected and seronegative subjects.
Journal of neuroimmunology 2005;163(1-2):145-56.
2005: Jay A Nelson; Huanyu Dou; Brent Ellison; Mariano Uberti; Huangui Xiong; Eric Anderson; M Mellon; Harris A Gelbard; Michael D Boska; Howard E Gendelman
Coregistration of quantitative proton magnetic resonance spectroscopic imaging with neuropathological and neurophysiological analyses defines the extent of neuronal impairments in murine human immunodeficiency virus type-1 encephalitis.
Journal of neuroscience research 2005;80(4):562-75.
2005: Masaru Yamamoto; Masahide Horiba; James L Buescher; DeReng Huang; Howard E Gendelman; Richard M Ransohoff; Tsuneya Ikezu
Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition.
The American journal of pathology 2005;166(5):1475-85.
2005: Michael D Boska; Travis B Lewis; Christopher J Destache; Eric J Benner; Jay A Nelson; Mariano Uberti; R Lee Mosley; Howard E Gendelman
Quantitative 1H magnetic resonance spectroscopic imaging determines therapeutic immunization efficacy in an animal model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(7):1691-700.
2005: Santhi Gorantla; Kathlyn Santos; Vakara Meyer; Stephen Dewhurst; William J Bowers; Howard Federoff; Howard E Gendelman; Larisa Poluektova
Human dendritic cells transduced with herpes simplex virus amplicons encoding human immunodeficiency virus type 1 (HIV-1) gp120 elicit adaptive immune responses from human cells engrafted into NOD/SCID mice and confer partial protection against HIV-1 challenge.
Journal of virology 2005;79(4):2124-32.
2005: Kathleen Borgmann; Howard E Gendelman; Anuja Ghorpade
Isolation and HIV-1 infection of primary human microglia from fetal and adult tissue.
Methods in molecular biology (Clifton, N.J.) 2005;304():49-70.
2005: Santhi Gorantla; Myhanh Che; Howard E Gendelman
Isolation, propagation, and HIV-1 infection of monocyte-derived macrophages and recovery of virus from brain and cerebrospinal fluid.
Methods in molecular biology (Clifton, N.J.) 2005;304():35-48.
2005: Howard E Gendelman; Yuri Persidsky
Infections of the nervous system.
Lancet neurology 2005;4(1):12-3.
2004: Pawel Ciborowski; Yoshimi Enose; Andrea Mack; Melissa Fladseth; Howard E Gendelman
Diminished matrix metalloproteinase 9 secretion in human immunodeficiency virus-infected mononuclear phagocytes: modulation of innate immunity and implications for neurological disease.
Journal of neuroimmunology 2004;157(1-2):11-6.
2004: Eric R Anderson; Howard E Gendelman; Huangui Xiong
Memantine protects hippocampal neuronal function in murine human immunodeficiency virus type 1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(32):7194-8.
2004: Eric J Benner; R Lee Mosley; Christopher J Destache; Travis B Lewis; Vernice Jackson-Lewis; Santhi Gorantla; Craig Nemachek; Steven R Green; Serge Przedborski; Howard E Gendelman
Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9435-40.
2004: Larisa Poluektova; Santhi Gorantla; Jill Faraci; Kevin Birusingh; Huanyu Dou; Howard E Gendelman
Neuroregulatory events follow adaptive immune-mediated elimination of HIV-1-infected macrophages: studies in a murine model of viral encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7610-7.
2004: Kimberly A Carlson; Jenae Limoges; Garrett D Pohlman; Larisa Poluektova; Dianne Langford; Eliezer Masliah; Tsuneya Ikezu; Howard E Gendelman
OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis.
Journal of neuroimmunology 2004;150(1-2):186-98.
2004: Lisa A Ryan; Hui Peng; David Erichsen; Yunlong Huang; Yuri Persidsky; You Zhou; Howard E Gendelman; Jialin Charles Zheng
TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia.
Journal of neuroimmunology 2004;148(1-2):127-39.
2004: Kimberly A Carlson; Pawel Ciborowski; Courtney N Schellpeper; Toni M Biskup; Rong-Fong Shen; Xiaoguang Luo; Christopher J Destache; Howard E Gendelman
Proteomic fingerprinting of HIV-1-infected human monocyte-derived macrophages: a preliminary report.
Journal of neuroimmunology 2004;147(1-2):35-42.
2004: Huanyu Dou; Jeffrey D Kingsley; R Lee Mosley; Harris A Gelbard; Howard E Gendelman
Neuroprotective strategies for HIV-1 associated dementia.
Neurotoxicity research 2004;6(7-8):503-21.
2004: Michael D Boska; R Lee Mosley; Mehmood Nawab; Jay A Nelson; Marina Zelivyanskaya; Larisa Poluektova; Mariano Uberti; Huanyu Dou; Travis B Lewis; Howard E Gendelman
Advances in neuroimaging for HIV-1 associated neurological dysfunction: clues to the diagnosis, pathogenesis and therapeutic monitoring.
Current HIV research 2004;2(1):61-78.
2004: Adeline Nukuna; Howard E Gendelman; Jenae Limoges; Jennifer Rasmussen; Larisa Poluektova; Anuja Ghorpade; Yuri Persidsky
Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis.
Journal of neurovirology 2004;10 Suppl 1():82-90.
2004: Valerie Wojna; Kimberly A Carlson; Xiaoguang Luo; Raul Mayo; Loyda M Meléndez; Edmundo Kraiselburd; Howard E Gendelman
Proteomic fingerprinting of human immunodeficiency virus type 1-associated dementia from patient monocyte-derived macrophages: A case study.
Journal of neurovirology 2004;10 Suppl 1():74-81.
2004: Kimberly A Carlson; Gary Leisman; Jenae Limoges; Garrett D Pohlman; Masahide Horiba; James L Buescher; Howard E Gendelman; Tsuneya Ikezu
Molecular characterization of a putative antiretroviral transcriptional factor, OTK18.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):381-91.
2003: Yuri Persidsky; Howard E Gendelman
Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection.
Journal of leukocyte biology 2003;74(5):691-701.
2003: Huanyu Dou; Kevin Birusingh; Jill Faraci; Santhi Gorantla; Larisa Poluektova; Sanjay B Maggirwar; Stephen Dewhurst; Harris A Gelbard; Howard E Gendelman
Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(27):9162-70.
2003: Radhika Suryadevara; Spring Holter; Kathleen Borgmann; Raisa Persidsky; Christine Labenz-Zink; Yuri Persidsky; Howard E Gendelman; Li Wu; Anuja Ghorpade
Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia.
Glia 2003;44(1):47-56.
2003: Annemarie Shibata; Marina Zelivyanskaya; Jenae Limoges; Kimberly A Carlson; Santhi Gorantla; Chad Branecki; Shrinivas Bishu; Huangui Xiong; Howard E Gendelman
Peripheral nerve induces macrophage neurotrophic activities: regulation of neuronal process outgrowth, intracellular signaling and synaptic function.
Journal of neuroimmunology 2003;142(1-2):112-29.
2003: Marina Zelivyanskaya; Jay A Nelson; Larisa Poluektova; Mariano Uberti; Melissa Mellon; Howard E Gendelman; Michael D Boska
Tracking superparamagnetic iron oxide labeled monocytes in brain by high-field magnetic resonance imaging.
Journal of neuroscience research 2003;73(3):284-95.
2003: Xiaoguang Luo; Kimberly A Carlson; Valerie Wojna; Raul Mayo; T M Biskup; J Stoner; J Anderson; Howard E Gendelman; Loyda M Meléndez
Macrophage proteomic fingerprinting predicts HIV-1-associated cognitive impairment.
Neurology 2003;60(12):1931-7.
2003: Huangui Xiong; Laura McCabe; Donald A Skifter; Daniel T Monaghan; Howard E Gendelman
Activation of NR1a/NR2B receptors by monocyte-derived macrophage secretory products: implications for human immunodeficiency virus type one-associated dementia.
Neuroscience letters 2003;341(3):246-50.
2003: David Erichsen; Alicia L Lopez; Hui Peng; Douglas Niemann; Clancy Williams; Michael Bauer; Susan Morgello; Robin L Cotter; Lisa A Ryan; Anuja Ghorpade; Howard E Gendelman; Jialin Charles Zheng
Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia.
Journal of neuroimmunology 2003;138(1-2):144-55.
2003: Huangui Xiong; Jeffrey Boyle; Matthew Winkelbauer; Santhi Gorantla; Jialin Charles Zheng; Anuja Ghorpade; Yuri Persidsky; Kimberly A Carlson; Howard E Gendelman
Inhibition of long-term potentiation by interleukin-8: implications for human immunodeficiency virus-1-associated dementia.
Journal of neuroscience research 2003;71(4):600-7.
2003: Xiaoguang Luo; Gregory A Weber; Jialin Charles Zheng; Howard E Gendelman; Tsuneya Ikezu
C1q-calreticulin induced oxidative neurotoxicity: relevance for the neuropathogenesis of Alzheimer's disease.
Journal of neuroimmunology 2003;135(1-2):62-71.
2003: E R Anderson; Jeffrey Boyle; Walter E Zink; Yuri Persidsky; Howard E Gendelman; Huangui Xiong
Hippocampal synaptic dysfunction in a murine model of human immunodeficiency virus type 1 encephalitis.
Neuroscience 2003;118(2):359-69.
2002: Yuri Persidsky; Howard E Gendelman
Murine models for human immunodeficiency virus type 1-associated dementia: the development of new treatment testing paradigms.
Journal of neurovirology 2002;8 Suppl 2():49-52.
2002: Howard E Gendelman
Neural immunity: Friend or foe?
Journal of neurovirology 2002;8(6):474-9.
2002: Eric Anderson; Walter E Zink; Huangui Xiong; Howard E Gendelman
HIV-1-associated dementia: a metabolic encephalopathy perpetrated by virus-infected and immune-competent mononuclear phagocytes.
Journal of acquired immune deficiency syndromes (1999) 2002;31 Suppl 2():S43-54.
2002: Thomas S Diesing; Susan Swindells; Harris A Gelbard; Howard E Gendelman
HIV-1-associated dementia: a basic science and clinical perspective.
The AIDS reader 2002;12(8):358-68.
2002: Larisa Poluektova; David H Munn; Yuri Persidsky; Howard E Gendelman
Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3941-9.
2002: Walter E Zink; Eric Anderson; Jeffrey Boyle; Lynette M Hock; Jorge Rodriguez-Sierra; Huangui Xiong; Howard E Gendelman; Yuri Persidsky
Impaired spatial cognition and synaptic potentiation in a murine model of human immunodeficiency virus type 1 encephalitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(6):2096-105.
2002: Lisa A Ryan; Robin L Cotter; Walter E Zink; Howard E Gendelman; Jialin Charles Zheng
Macrophages, chemokines and neuronal injury in HIV-1-associated dementia.
Cellular and molecular biology (Noisy-le-Grand, France) 2002;48(2):137-50.
2002: Induk Chung; Marina Zelivyanskaya; Howard E Gendelman
Mononuclear phagocyte biophysiology influences brain transendothelial and tissue migration: implication for HIV-1-associated dementia.
Journal of neuroimmunology 2002;122(1-2):40-54.
2001: Larisa Poluektova; T Moran; Marina Zelivyanskaya; Susan Swindells; Howard E Gendelman; Yuri Persidsky
The regulation of alpha chemokines during HIV-1 infection and leukocyte activation: relevance for HIV-1-associated dementia.
Journal of neuroimmunology 2001;120(1-2):112-28.
2001: Jialin Charles Zheng; MR Thylin; Yuri Persidsky; C E Williams; Robin L Cotter; Walter E Zink; L Ryan; Anuja Ghorpade; K Lewis; Howard E Gendelman
HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise.
Neurotoxicity research 2001;3(5):461-84.
2001: Jialin Charles Zheng; MR Thylin; Robin L Cotter; Alicia L Lopez; Anuja Ghorpade; Yuri Persidsky; Huangui Xiong; G B Leisman; MH Che; Howard E Gendelman
HIV-1 infected and immune competent mononuclear phagocytes induce quantitative alterations in neuronal dendritic arbor: relevance for HIV-1-associated dementia.
Neurotoxicity research 2001;3(5):443-59.
2001: Lisa A Ryan; Jialin Charles Zheng; Michelle Brester; Daryl Bohac; F Hahn; J Anderson; W Ratanasuwan; Howard E Gendelman; Susan Swindells
Plasma levels of soluble CD14 and tumor necrosis factor-alpha type II receptor correlate with cognitive dysfunction during human immunodeficiency virus type 1 infection.
The Journal of infectious diseases 2001;184(6):699-706.
2001: Anuja Ghorpade; RN Persidskaia; R Suryadevara; MH Che; X J Liu; Yuri Persidsky; Howard E Gendelman
Mononuclear phagocyte differentiation, activation, and viral infection regulate matrix metalloproteinase expression: implications for human immunodeficiency virus type 1-associated dementia.
Journal of virology 2001;75(14):6572-83.
2001: Robin L Cotter; Jialin Charles Zheng; MH Che; Douglas Niemann; Y Liu; J He; E Thomas; Howard E Gendelman
Regulation of human immunodeficiency virus type 1 infection, beta-chemokine production, and CCR5 expression in CD40L-stimulated macrophages: immune control of viral entry.
Journal of virology 2001;75(9):4308-20.
2001: Yuri Persidsky; Jenae Limoges; Jennifer Rasmussen; Jialin Charles Zheng; A Gearing; Howard E Gendelman
Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis.
Journal of neuroimmunology 2001;114(1-2):57-68.
2001: Jenae Limoges; Larisa Poluektova; W Ratanasuwan; Jennifer Rasmussen; Marina Zelivyanskaya; Daniel R McClernon; E Randall Lanier; Howard E Gendelman; Yuri Persidsky
The efficacy of potent anti-retroviral drug combinations tested in a murine model of HIV-1 encephalitis.
Virology 2001;281(1):21-34.
2001: Walter E Zink; Jeffrey Boyle; Yuri Persidsky; Huangui Xiong; Howard E Gendelman
Model systems for assessing cognitive function: implications for HIV-1 infection and drugs of abuse.
Advances in experimental medicine and biology 2001;493():7-27.
2000: Yuri Persidsky; Jialin Charles Zheng; D Miller; Howard E Gendelman
Mononuclear phagocytes mediate blood-brain barrier compromise and neuronal injury during HIV-1-associated dementia.
Journal of leukocyte biology 2000;68(3):413-22.
2000: Huangui Xiong; YC Zeng; T Lewis; Jialin Charles Zheng; Yuri Persidsky; Howard E Gendelman
HIV-1 infected mononuclear phagocyte secretory products affect neuronal physiology leading to cellular demise: relevance for HIV-1-associated dementia.
Journal of neurovirology 2000;6 Suppl 1():S14-23.
2000: Ning Tong; Seth W Perry; Qian Zhang; HJ James; Huang Guo; A Brooks; H Bal; S A Kinnear; S Fine; Leon G Epstein; Daniel J Dairaghi; Thomas J Schall; Howard E Gendelman; Stephen Dewhurst; Leroy R Sharer; Harris A Gelbard
Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1333-9.
2000: Jenae Limoges; Yuri Persidsky; Larisa Poluektova; Jennifer Rasmussen; W Ratanasuwan; Marina Zelivyanskaya; Daniel R McClernon; E Randall Lanier; Howard E Gendelman
Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice.
Neurology 2000;54(2):379-89.
1999: Walter E Zink; Jialin Charles Zheng; Yuri Persidsky; Larisa Poluektova; Howard E Gendelman
The neuropathogenesis of HIV-1 infection.
FEMS immunology and medical microbiology 1999;26(3-4):233-41.
1999: Yuri Persidsky; Anuja Ghorpade; Jennifer Rasmussen; Jenae Limoges; X J Liu; Monique F Stins; Milan Fiala; DL Way; KS Kim; Marlys H Witte; Martin Weinand; L Carhart; Howard E Gendelman
Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis.
The American journal of pathology 1999;155(5):1599-611.
1999: Huangui Xiong; YC Zeng; Jialin Charles Zheng; MR Thylin; Howard E Gendelman
Soluble HIV-1 infected macrophage secretory products mediate blockade of long-term potentiation: a mechanism for cognitive dysfunction in HIV-1-associated dementia.
Journal of neurovirology 1999;5(5):519-28.
1999: Jialin Charles Zheng; Anuja Ghorpade; Douglas Niemann; Robin L Cotter; MR Thylin; L Epstein; J M Swartz; R B Shepard; X Liu; Adeline Nukuna; Howard E Gendelman
Lymphotropic virions affect chemokine receptor-mediated neural signaling and apoptosis: implications for human immunodeficiency virus type 1-associated dementia.
Journal of virology 1999;73(10):8256-67.
1999: Jialin Charles Zheng; MR Thylin; Anuja Ghorpade; Huangui Xiong; Yuri Persidsky; Robin Cotter; Douglas Niemann; MH Che; YC Zeng; Harris A Gelbard; R B Shepard; J M Swartz; Howard E Gendelman
Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia.
Journal of neuroimmunology 1999;98(2):185-200.
1999: Jinan Al-Omaishi; R Bashir; Howard E Gendelman
The cellular immunology of multiple sclerosis.
Journal of leukocyte biology 1999;65(4):444-52.
1999: Robin L Cotter; W J Burke; Vince Thomas; Jane F Potter; Jialin Charles Zheng; Howard E Gendelman
Insights into the neurodegenerative process of Alzheimer's disease: a role for mononuclear phagocyte-associated inflammation and neurotoxicity.
Journal of leukocyte biology 1999;65(4):416-27.
1999: Howard E Gendelman; David G Folks
Innate and acquired immunity in neurodegenerative disorders.
Journal of leukocyte biology 1999;65(4):407-8.
1999: Susan Swindells; Jialin Charles Zheng; Howard E Gendelman
HIV-associated dementia: new insights into disease pathogenesis and therapeutic interventions.
AIDS patient care and STDs 1999;13(3):153-63.
1999: Huangui Xiong; Jialin Charles Zheng; MR Thylin; Howard E Gendelman
Unraveling the mechanisms of neurotoxicity in HIV type 1-associated dementia: inhibition of neuronal synaptic transmission by macrophage secretory products.
AIDS research and human retroviruses 1999;15(1):57-63.
1998: Howard E Gendelman; Jialin Charles Zheng; C L Coulter; Anuja Ghorpade; MH Che; MR Thylin; Ronald J Rubocki; Yuri Persidsky; F Hahn; J Reinhard; Susan Swindells
Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia.
The Journal of infectious diseases 1998;178(4):1000-7.
1998: Anuja Ghorpade; MengQi Xia; Bradley T Hyman; Yuri Persidsky; Adeline Nukuna; P Bock; MH Che; Jenae Limoges; Howard E Gendelman; C R Mackay
Role of the beta-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia.
Journal of virology 1998;72(4):3351-61.
1998: Anuja Ghorpade; Adeline Nukuna; MH Che; S Haggerty; Yuri Persidsky; E Carter; L Carhart; Laura R Shafer; Howard E Gendelman
Human immunodeficiency virus neurotropism: an analysis of viral replication and cytopathicity for divergent strains in monocytes and microglia.
Journal of virology 1998;72(4):3340-50.
1997: Yuri Persidsky; M Buttini; Jenae Limoges; P Bock; Howard E Gendelman
An analysis of HIV-1-associated inflammatory products in brain tissue of humans and SCID mice with HIV-1 encephalitis.
Journal of neurovirology 1997;3(6):401-16.
1997: Jialin Charles Zheng; Howard E Gendelman
The HIV-1 associated dementia complex: a metabolic encephalopathy fueled by viral replication in mononuclear phagocytes.
Current opinion in neurology 1997;10(4):319-25.
1997: Yuri Persidsky; Howard E Gendelman
Development of laboratory and animal model systems for HIV-1 encephalitis and its associated dementia.
Journal of leukocyte biology 1997;62(1):100-6.
1997: S Krajewski; HJ James; J Ross; B M Blumberg; Leon G Epstein; Howard E Gendelman; S Gummuluru; Stephen Dewhurst; Leroy R Sharer; J C Reed; Harris A Gelbard
Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis.
Neuropathology and applied neurobiology 1997;23(3):242-53.
1997: Jenae Limoges; Yuri Persidsky; P Bock; Howard E Gendelman
Dexamethasone therapy worsens the neuropathology of human immunodeficiency virus type 1 encephalitis in SCID mice.
The Journal of infectious diseases 1997;175(6):1368-81.
1997: Yuri Persidsky; Monique F Stins; DL Way; Marlys H Witte; Martin Weinand; KS Kim; P Bock; Howard E Gendelman; Milan Fiala
A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3499-510.
1997: Howard E Gendelman; Yuri Persidsky; Anuja Ghorpade; Jenae Limoges; Monique F Stins; Milan Fiala; Richard A Morrisett
The neuropathogenesis of the AIDS dementia complex.
AIDS (London, England) 1997;11 Suppl A():S35-45.
1996: Yuri Persidsky; Jenae Limoges; R McComb; P Bock; T Baldwin; William R Tyor; A Patil; H S Nottet; L Epstein; Harris A Gelbard; E Flanagan; J Reinhard; Samuel J Pirruccello; Howard E Gendelman
Human immunodeficiency virus encephalitis in SCID mice.
The American journal of pathology 1996;149(3):1027-53.
1996: H S Nottet; E M Flanagan; C R Flanagan; Harris A Gelbard; Howard E Gendelman; J F Reinhard
The regulation of quinolinic acid in human immunodeficiency virus-infected monocytes.
Journal of neurovirology 1996;2(2):111-7.
1996: Susan Swindells; T Baldwin; C Kelly; L Baca-Regen; L Loomis; D Post; Beda Brichacek; Mario Stevenson; E A Dominguez; R Reddy; R Klein; M J Liao; D Testa; T McDonald; J Bellanti; S Skurkovich; Howard E Gendelman
Regulation and characterization of the interferon-alpha present in patients with advanced human immunodeficiency virus type 1 disease.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1996;16(2):127-37.
1996: H S Nottet; Yuri Persidsky; V G Sasseville; Adeline Nukuna; P Bock; Q H Zhai; L R Sharer; R D McComb; Susan Swindells; C Soderland; Howard E Gendelman
Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):1284-95.
1996: Helena Schmidtmayerova; H S Nottet; G Nuovo; T Raabe; C R Flanagan; Larisa Dubrovsky; Howard E Gendelman; Anthony Cerami; Michael Bukrinsky; Barbara Sherry
Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(2):700-4.
1995: Susan Swindells; J R McConnell; R D McComb; Howard E Gendelman
Utility of cerebral proton magnetic resonance spectroscopy in differential diagnosis of HIV-related dementia.
Journal of neurovirology 1995;1(3-4):268-74.
1995: Yuri Persidsky; H S Nottet; V G Sasseville; L G Epstein; Howard E Gendelman
The development of animal model systems for HIV-1 encephalitis and its associated dementia.
Journal of neurovirology 1995;1(3-4):229-43.
1995: H S Nottet; Howard E Gendelman
Unraveling the neuroimmune mechanisms for the HIV-1-associated cognitive/motor complex.
Immunology today 1995;16(9):441-8.
1995: Michael Bukrinsky; H S Nottet; Helena Schmidtmayerova; Larisa Dubrovsky; C R Flanagan; M E Mullins; S A Lipton; Howard E Gendelman
Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease.
The Journal of experimental medicine 1995;181(2):735-45.
1995: N Heinzinger; L Baca-Regen; Mario Stevenson; Howard E Gendelman
Efficient synthesis of viral nucleic acids following monocyte infection by HIV-1.
Virology 1995;206(1):731-5.
1994: L Baca-Regen; N Heinzinger; Mario Stevenson; Howard E Gendelman
Alpha interferon-induced antiretroviral activities: restriction of viral nucleic acid synthesis and progeny virion production in human immunodeficiency virus type 1-infected monocytes.
Journal of virology 1994;68(11):7559-65.
1994: Howard E Gendelman; T Baldwin; L Baca-Regen; Susan Swindells; L Loomis; S Skurkovich
Regulation of HIV1 replication by interferon alpha: from laboratory bench to bedside.
Research in immunology 1994;145(8-9):679-84; discussion 684-5.
1994: Howard E Gendelman; S A Lipton; M Tardieu; Michael Bukrinsky; H S Nottet
The neuropathogenesis of HIV-1 infection.
Journal of leukocyte biology 1994;56(3):389-98.
1994: Howard E Gendelman; M Tardieu
Macrophages/microglia and the pathophysiology of CNS injuries in AIDS.
Journal of leukocyte biology 1994;56(3):387-8.
1994: Mario Stevenson; Howard E Gendelman
Cellular and viral determinants that regulate HIV-1 infection in macrophages.
Journal of leukocyte biology 1994;56(3):278-88.
1994: J R McConnell; Susan Swindells; C S Ong; William H Gmeiner; W K Chu; D K Brown; Howard E Gendelman
Prospective utility of cerebral proton magnetic resonance spectroscopy in monitoring HIV infection and its associated neurological impairment.
AIDS research and human retroviruses 1994;10(8):977-82.
1994: N K Heinzinger; M I Bukinsky; S A Haggerty; A M Ragland; V Kewalramani; M A Lee; Howard E Gendelman; L Ratner; Mario Stevenson; M Emerman
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7311-5.
1994: L M Baca; P Genis; Dhan V Kalvakolanu; G Sen; M S Meltzer; A Zhou; R Silverman; Howard E Gendelman
Regulation of interferon-alpha-inducible cellular genes in human immunodeficiency virus-infected monocytes.
Journal of leukocyte biology 1994;55(3):299-309.
1994: Howard E Gendelman; P Genis; Marti Jett; Q H Zhai; H S Nottet
An experimental model system for HIV-1-induced brain injury.
Advances in neuroimmunology 1994;4(3):189-93.
1994: J A Turpin; S X Fan; B D Hansen; M L Francis; L M Baca-Regen; Howard E Gendelman; M S Meltzer
Regulation of HIV replication in monocytes by interferon.
Progress in molecular and subcellular biology 1994;14():222-41.
1993: William R Tyor; C Power; Howard E Gendelman; Richard B Markham
A model of human immunodeficiency virus encephalitis in scid mice.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(18):8658-62.
1992: B D Hansen; P L Nara; R K Maheshwari; G S Sidhu; J G Bernbaum; D Hoekzema; M S Meltzer; Howard E Gendelman
Loss of infectivity by progeny virus from alpha interferon-treated human immunodeficiency virus type 1-infected T cells is associated with defective assembly of envelope gp120.
Journal of virology 1992;66(12):7543-8.
1992: M L Francis; M S Meltzer; Howard E Gendelman
Interferons in the persistence, pathogenesis, and treatment of HIV infection.
AIDS research and human retroviruses 1992;8(2):199-207.
1992: Howard E Gendelman; L M Baca; C A Kubrak; P Genis; S Burrous; R M Friedman; D Jacobs; M S Meltzer
Induction of IFN-alpha in peripheral blood mononuclear cells by HIV-infected monocytes. Restricted antiviral activity of the HIV-induced IFN.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(2):422-9.
1992: Howard E Gendelman; D R Skillman; M S Meltzer
Interferon alpha (IFN)-macrophage interactions in human immunodeficiency virus (HIV) infection: role of IFN in the tempo and progression of HIV disease.
International reviews of immunology 1992;8(1):43-54.
1991: D C Kalter; Howard E Gendelman; M S Meltzer
Inhibition of human immunodeficiency virus infection in monocytes by monoclonal antibodies against leukocyte adhesion molecules.
Immunology letters 1991;30(2):219-27.
1991: Howard E Gendelman; G D Ehrlich; L M Baca; S Conley; J Ribas; D C Kalter; M S Meltzer; B J Poiesz; P Nara
The inability of human immunodeficiency virus to infect chimpanzee monocytes can be overcome by serial viral passage in vivo.
Journal of virology 1991;65(7):3853-63.
1991: Howard E Gendelman; R M Friedman; S Joe; L M Baca; J A Turpin; Gabriela S Dveksler; M S Meltzer; Carl W Dieffenbach
A selective defect of interferon alpha production in human immunodeficiency virus-infected monocytes.
The Journal of experimental medicine 1991;173(1):277.
1991: M S Meltzer; L Baca; J A Turpin; D C Kalter; Carl W Dieffenbach; R M Friedman; Howard E Gendelman
Regulation of cytokine and viral gene expression in monocytes infected with the human immunodeficiency virus.
Pathobiology : journal of immunopathology, molecular and cellular biology 1991;59(4):209-13.
1991: D C Kalter; M Nakamura; J A Turpin; L M Baca; D L Hoover; Carl W Dieffenbach; P Ralph; Howard E Gendelman; M S Meltzer
Enhanced HIV replication in macrophage colony-stimulating factor-treated monocytes.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(1):298-306.
1990: Howard E Gendelman; R M Friedman; S Joe; L M Baca; J A Turpin; Gabriela S Dveksler; M S Meltzer; Carl W Dieffenbach
A selective defect of interferon alpha production in human immunodeficiency virus-infected monocytes.
The Journal of experimental medicine 1990;172(5):1433-42.
1990: Howard E Gendelman; L M Baca; J Turpin; D C Kalter; B Hansen; J M Orenstein; Carl W Dieffenbach; R M Friedman; M S Meltzer
Regulation of HIV replication in infected monocytes by IFN-alpha. Mechanisms for viral restriction.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(8):2669-76.
1990: M S Meltzer; M Nakamura; B D Hansen; J A Turpin; D C Kalter; Howard E Gendelman
Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease.
AIDS research and human retroviruses 1990;6(8):967-71.
1990: Howard E Gendelman; L Baca; J A Turpin; D C Kalter; B D Hansen; J M Orenstein; R M Friedman; M S Meltzer
Restriction of HIV replication in infected T cells and monocytes by interferon-alpha.
AIDS research and human retroviruses 1990;6(8):1045-9.
1990: P J Gomatos; Nicholas M Stamatos; Howard E Gendelman; A Fowler; D L Hoover; D C Kalter; Donald S. Burke; E C Tramont; M S Meltzer
Relative inefficiency of soluble recombinant CD4 for inhibition of infection by monocyte-tropic HIV in monocytes and T cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(11):4183-8.
1990: M S Meltzer; D R Skillman; D L Hoover; B D Hanson; J A Turpin; D C Kalter; Howard E Gendelman
Macrophages and the human immunodeficiency virus.
Immunology today 1990;11(6):217-23.
1990: Howard E Gendelman; L M Baca; H Husayni; J A Turpin; D Skillman; D C Kalter; J M Orenstein; D L Hoover; M S Meltzer
Macrophage-HIV interaction: viral isolation and target cell tropism.
AIDS (London, England) 1990;4(3):221-8.
1990: M S Meltzer; D R Skillman; P J Gomatos; D C Kalter; Howard E Gendelman
Role of mononuclear phagocytes in the pathogenesis of human immunodeficiency virus infection.
Annual review of immunology 1990;8():169-94.
1990: Howard E Gendelman; L M Baca; J A Turpin; D C Kalter; Carl W Dieffenbach; R M Friedman; M S Meltzer
Interactions between interferon and the human immunodeficiency virus.
Journal of experimental pathology 1990;5(2):53-67.
1989: Howard E Gendelman; J M Orenstein; L M Baca; B Weiser; H Burger; D C Kalter; M S Meltzer
The macrophage in the persistence and pathogenesis of HIV infection.
AIDS (London, England) 1989;3(8):475-95.
1988: M S Meltzer; Howard E Gendelman
Effects of colony stimulating factors on the interaction of monocytes and the human immunodeficiency virus.
Immunology letters 1988;19(3):193-8.