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Saul Genuth

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Vincent M Monnier; David R Sell; Christopher M Strauch; Wanjie Sun; Patricia A Cleary; Saul Genuth; John M Lachin
The association between skin collagen glucosepane and past progression of microvascular and neuropathic complications in type 1 diabetes.
Mary E Larkin; Gayle M Lorenzi; Ellen Golden; Susan Hitt; Annette Barnie; Meg Bayless; Patricia A Cleary; Saul Genuth
Evolution of the study coordinator role: the 28-year experience in Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC).
Faramarz Ismail-Beigi; Diane Karl; Lois Katz; Patrick J O'Connor; Jeffrey L Probstfield; Ulrich Schubart; Jorge Calles-Escandon; Timothy E Craven; William C Cushman; Saul Genuth; Hertzel C Gerstein; Irene Hramiak
Combined intensive blood pressure and glycemic control does not produce an additive benefit on microvascular outcomes in type 2 diabetic patients.

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All Publications

2013: Vincent M Monnier; David R Sell; Christopher M Strauch; Wanjie Sun; Patricia A Cleary; Saul Genuth; John M Lachin
The association between skin collagen glucosepane and past progression of microvascular and neuropathic complications in type 1 diabetes.
Journal of diabetes and its complications 2013;27(2):141-9.
2012: Mary E Larkin; Gayle M Lorenzi; Ellen Golden; Susan Hitt; Annette Barnie; Meg Bayless; Patricia A Cleary; Saul Genuth
Evolution of the study coordinator role: the 28-year experience in Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC).
Clinical trials (London, England) 2012;9(4):418-25.
2012: Faramarz Ismail-Beigi; Diane Karl; Lois Katz; Patrick J O'Connor; Jeffrey L Probstfield; Ulrich Schubart; Jorge Calles-Escandon; Timothy E Craven; William C Cushman; Saul Genuth; Hertzel C Gerstein; Irene Hramiak
Combined intensive blood pressure and glycemic control does not produce an additive benefit on microvascular outcomes in type 2 diabetic patients.
Kidney international 2012;81(6):586-94.
2011: Evrim B Turkbey; Rob J van der Geest; Jye-Yu C Backlund; David A Bluemke; Patricia A Cleary; Saul Genuth; Aditya Jain; John M Lachin; João A C Lima; Chia-Ying Liu; Cuilian Miao; David M Nathan; Elsayed Z Soliman
Myocardial structure, function, and scar in patients with type 1 diabetes mellitus.
Circulation 2011;124(16):1737-46.
2011: Burton E Sobel; Robert Wolk; Maria M Brooks; Robert L Frye; Saul Genuth; Regina M Hardison; Kurt Huber; Ashok Krishnaswami; Robert D McBane; Richard E Pratley; David J Schneider
Profibrinolytic, antithrombotic, and antiinflammatory effects of an insulin-sensitizing strategy in patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial.
Circulation 2011;124(6):695-703.
2011: Faramarz Ismail-Beigi; Etie Moghissi; Margaret Tiktin; Irl B Hirsch; Silvio E Inzucchi; Saul Genuth
Individualizing glycemic targets in type 2 diabetes mellitus: implications of recent clinical trials.
Annals of internal medicine 2011;154(8):554-9.
2011: Hertzel C Gerstein; Michael E Miller; Saul Genuth; Faramarz Ismail-Beigi; John B Buse; David C Goff; Jeffrey L Probstfield; William C Cushman; Henry N Ginsberg; J Thomas Bigger; Richard H Grimm; Robert P Byington; Yves D Rosenberg; William T Friedewald
Long-term effects of intensive glucose lowering on cardiovascular outcomes.
The New England journal of medicine 2011;364(9):818-28.
2010: Dima Abdelmannan; Rundsara Tahboub; Saul Genuth; Faramarz Ismail-Beigi
Effect of dexamethasone on oral glucose tolerance in healthy adults.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2010;16(5):770-7.
2010: Faramarz Ismail-Beigi; Timothy Craven; Mary Ann Banerji; Jan Basile; Jorge Calles; Robert M Cohen; Robert Cuddihy; William C Cushman; Saul Genuth; Richard H Grimm; Bruce P Hamilton; Byron Hoogwerf; Diane Karl; Lois Katz; Armand Krikorian; Patrick O'Connor; Rodica Pop-Busui; Ulrich Schubart; Debra Simmons; Harris Taylor; Abraham H. Thomas; Daniel Weiss; Irene Hramiak
Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial.
Lancet 2010;376(9739):419-30.
2010: Emily Y Chew; Walter T Ambrosius; Matthew D Davis; Ronald P Danis; Sapna Gangaputra; Craig M Greven; Larry Hubbard; Barbara A Esser; James F Lovato; Letitia H Perdue; David C Goff; William C Cushman; Henry N Ginsberg; Marshall B Elam; Saul Genuth; Hertzel C Gerstein; Ulrich Schubart; Lawrence Fine
Effects of medical therapies on retinopathy progression in type 2 diabetes.
The New England journal of medicine 2010;363(3):233-44.
2010: Rodica Pop-Busui; Gregory W Evans; Hertzel C Gerstein; Vivian Fonseca; Jerome L Fleg; Byron J Hoogwerf; Saul Genuth; Richard H Grimm; Marshall A Corson; Ronald Prineas
Effects of cardiac autonomic dysfunction on mortality risk in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.
Diabetes care 2010;33(7):1578-84.
2010: Elizabeth F O Kern; Penny Erhard; Wanjie Sun; Saul Genuth; Miriam F Weiss
Early urinary markers of diabetic kidney disease: a nested case-control study from the Diabetes Control and Complications Trial (DCCT).
American journal of kidney diseases : the official journal of the National Kidney Foundation 2010;55(5):824-34.
2010: Lesley A Stevens; Christopher Schmid; Yaping L Zhang; Josef Coresh; Jane Manzi; Richard Landis; Omran Bakoush; Gabriel Contreras; Saul Genuth; Goran B Klintmalm; Emilio Poggio; Peter Rossing; Andrew D Rule; Matthew R Weir; John W Kusek; Tom Greene; Andrew S Levey
Development and validation of GFR-estimating equations using diabetes, transplant and weight.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(2):449-57.
2010: Michael E Miller; Denise E Bonds; Hertzel C Gerstein; Elizabeth R Seaquist; Richard M Bergenstal; Jorge Calles-Escandon; R Dale Childress; Timothy E Craven; Robert M Cuddihy; George Dailey; Mark N Feinglos; Farmarz Ismail-Beigi; Joe F Largay; Patrick J O'Connor; Terri Paul; Peter J Savage; Ulrich Schubart; Ajay Sood; Saul Genuth
The effects of baseline characteristics, glycaemia treatment approach, and glycated haemoglobin concentration on the risk of severe hypoglycaemia: post hoc epidemiological analysis of the ACCORD study.
BMJ (Clinical research ed.) 2010;340():b5444.
2009: David M Nathan; Bernard Zinman; Patricia A Cleary; Jye-Yu C Backlund; Saul Genuth; Rachel Miller; Trevor J Orchard
Modern-day clinical course of type 1 diabetes mellitus after 30 years' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience (1983-2005).
Archives of internal medicine 2009;169(14):1307-16.
2008: Saul Genuth
The UKPDS and its global impact.
Diabetic medicine : a journal of the British Diabetic Association 2008;25 Suppl 2():57-62.
2008: Hertzel C Gerstein; Michael E Miller; Robert P Byington; David C Goff; J Thomas Bigger; John B Buse; William Cushman; Saul Genuth; Faramarz Ismail-Beigi; Richard H Grimm; Jeffrey L Probstfield; Denise Simons-Morton; William T Friedewald
Effects of intensive glucose lowering in type 2 diabetes.
The New England journal of medicine 2008;358(24):2545-59.
2008: Saul Genuth; Richard Kahn
A step backward--or is it forward?
Diabetes care 2008;31(6):1093-6.
2008: John M Lachin; Saul Genuth; David M Nathan; Bernard Zinman; Brandy N Rutledge
Effect of glycemic exposure on the risk of microvascular complications in the diabetes control and complications trial--revisited.
Diabetes 2008;57(4):995-1001.
2007: John M Lachin; Saul Genuth; David M Nathan; Brandy N Rutledge
The hemoglobin glycation index is not an independent predictor of the risk of microvascular complications in the Diabetes Control and Complications Trial.
Diabetes 2007;56(7):1913-21.
2007: David C Goff; Hertzel C Gerstein; Henry N Ginsberg; William Cushman; Karen L Margolis; Robert P Byington; John B Buse; Saul Genuth; Jeffrey L Probstfield; Denise Simons-Morton
Prevention of cardiovascular disease in persons with type 2 diabetes mellitus: current knowledge and rationale for the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.
The American journal of cardiology 2007;99(12A):4i-20i.
2007: John B Buse; J Thomas Bigger; Robert P Byington; Lawton S Cooper; William Cushman; William T Friedewald; Saul Genuth; Hertzel C Gerstein; Henry N Ginsberg; David C Goff; Richard H Grimm; Karen L Margolis; Jeffrey L Probstfield; Denise Simons-Morton; Mark D Sullivan
Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial: design and methods.
The American journal of cardiology 2007;99(12A):21i-33i.
2007: Emily Y Chew; Walter T Ambrosius; Letitia T Howard; Craig M Greven; Samantha Johnson; Ronald P Danis; Matthew D Davis; Saul Genuth; Michael Domanski
Rationale, design, and methods of the Action to Control Cardiovascular Risk in Diabetes Eye Study (ACCORD-EYE).
The American journal of cardiology 2007;99(12A):103i-111i.
2006: Patricia A Cleary; Trevor J Orchard; Saul Genuth; Nathan D Wong; Robert Detrano; Jye-Yu C Backlund; Bernard Zinman; Alan Jacobson; Wanjie Sun; John M Lachin; David M Nathan
The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study.
Diabetes 2006;55(12):3556-65.
2006: Maria Mori Brooks; Robert L Frye; Saul Genuth; Katherine M Detre; Richard W Nesto; Burton E Sobel; Sheryl F Kelsey; Trevor J Orchard
Hypotheses, design, and methods for the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial.
The American journal of cardiology 2006;97(12A):9G-19G.
2006: Saul Genuth
Insights from the diabetes control and complications trial/epidemiology of diabetes interventions and complications study on the use of intensive glycemic treatment to reduce the risk of complications of type 1 diabetes.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2006;12 Suppl 1():34-41.
2005: David M Nathan; Patricia A Cleary; Jye-Yu C Backlund; Saul Genuth; John M Lachin; Trevor J Orchard; Philip Raskin; Bernard Zinman
Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.
The New England journal of medicine 2005;353(25):2643-53.
2005: Saul Genuth; Wanjie Sun; Patricia Cleary; David R Sell; William Dahms; John Malone; William I Sivitz; Vincent M Monnier
Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications participants with type 1 diabetes.
Diabetes 2005;54(11):3103-11.
2005: Vincent M Monnier; David R Sell; Saul Genuth
Glycation products as markers and predictors of the progression of diabetic complications.
Annals of the New York Academy of Sciences 2005;1043():567-81.
2005: Denise Simons-Morton; Saul Genuth; Robert P Byington; Hertzel C Gerstein; William T Friedewald
The burden of treatment failure in type 2 diabetes: response to Brown et al.
Diabetes care 2005;28(3):761-2.
2005: Saul Genuth; John M Lachin; David M Nathan
Biological variation in HbA1c predicts risk of retinopathy and nephropathy in type 1 diabetes: response to McCarter et al.
Diabetes care 2005;28(1):233; author reply 234-5.
2003: Saul Genuth
Lowering the criterion for impaired fasting glucose is in order.
Diabetes care 2003;26(12):3331-2.
2003: Saul Genuth; K G M M Alberti; Peter Bennett; John B Buse; Ralph DeFronzo; Richard Kahn; John Kitzmiller; William C Knowler; Harold E Lebovitz; Ake Lernmark; David Nathan; Jerry Palmer; Robert A Rizza; Christopher D Saudek; Jonathan Shaw; Michael Steffes; Michael P Stern; Jaako Tuomilehto; Paul Zimmet
Follow-up report on the diagnosis of diabetes mellitus.
Diabetes care 2003;26(11):3160-7.
2003: David M Nathan; John M Lachin; Patricia Cleary; Trevor Orchard; David J Brillon; Jye-Yu C Backlund; Daniel H O'Leary; Saul Genuth
Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus.
The New England journal of medicine 2003;348(23):2294-303.
2003: Saul Genuth; Richard Eastman; Richard Kahn; Ronald Klein; John M Lachin; Harold E Lebovitz; David Nathan; Frank Vinicor
Implications of the United kingdom prospective diabetes study.
Diabetes care 2003;26 Suppl 1():S28-32.
2000: Saul Genuth
Implications of the United Kingdom prospective diabetes study for patients with obesity and type 2 diabetes.
Obesity research 2000;8(2):198-201.
1999: Vincent M Monnier; O Bautista; D Kenny; David R Sell; J Fogarty; William Dahms; Patricia A Cleary; John M Lachin; Saul Genuth
Skin collagen glycation, glycoxidation, and crosslinking are lower in subjects with long-term intensive versus conventional therapy of type 1 diabetes: relevance of glycated collagen products versus HbA1c as markers of diabetic complications. DCCT Skin Collagen Ancillary Study Group. Diabetes Control and Complications Trial.
Diabetes 1999;48(4):870-80.
1997: Saul Genuth
Diabetic ketoacidosis and hyperglycemic hyperosmolar coma.
Current therapy in endocrinology and metabolism 1997;6():438-47.