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Biljana Georgievska

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Biljana Georgievska; Susanne Gruber; Sven Hellberg; Anette Mörtberg; Jan Neelissen; Yvonne Nilsson; Gunilla Osswald; Johan Sandin; Pär Schött; Anita Andersson; Per I Arvidsson; Stefan Berg; James Doherty; Johanna Fälting; Ratan V Bhat
AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
Britt-Marie Swahn; Dominika Turek; Stefan von Berg; Fredrik von Kieseritzky; Lars Andersson; Stefan Berg; Margareta Bergh; Krisztian Bogar; Susanna Eketjäll; Biljana Georgievska; Jörg Holenz; Juliette Janson; Fredrik Jeppsson; Sofia Karlström; Annika Kers; Jacob Kihlström; Karin Kolmodin; Johan Lindström; Liselotte Ohberg; Lise-Lotte Olsson; David Pyring; Didier Rotticci; Can Slivo; Peter Söderman; Marie Sundström; Johanna Fälting
Design and synthesis of β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors with in vivo brain reduction of β-amyloid peptides.
Nadia Stefanova; Håkan Eriksson; Biljana Georgievska; Werner Poewe; Gregor K Wenning
Myeloperoxidase inhibition ameliorates multiple system atrophy-like degeneration in a transgenic mouse model.

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All Publications

2013: Biljana Georgievska; Susanne Gruber; Sven Hellberg; Anette Mörtberg; Jan Neelissen; Yvonne Nilsson; Gunilla Osswald; Johan Sandin; Pär Schött; Anita Andersson; Per I Arvidsson; Stefan Berg; James Doherty; Johanna Fälting; Ratan V Bhat
AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
Journal of neurochemistry 2013;125(3):446-56.
2012: Britt-Marie Swahn; Dominika Turek; Stefan von Berg; Fredrik von Kieseritzky; Lars Andersson; Stefan Berg; Margareta Bergh; Krisztian Bogar; Susanna Eketjäll; Biljana Georgievska; Jörg Holenz; Juliette Janson; Fredrik Jeppsson; Sofia Karlström; Annika Kers; Jacob Kihlström; Karin Kolmodin; Johan Lindström; Liselotte Ohberg; Lise-Lotte Olsson; David Pyring; Didier Rotticci; Can Slivo; Peter Söderman; Marie Sundström; Johanna Fälting
Design and synthesis of β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors with in vivo brain reduction of β-amyloid peptides.
Journal of medicinal chemistry 2012;55(21):9346-61.
2012: Nadia Stefanova; Håkan Eriksson; Biljana Georgievska; Werner Poewe; Gregor K Wenning
Myeloperoxidase inhibition ameliorates multiple system atrophy-like degeneration in a transgenic mouse model.
Neurotoxicity research 2012;21(4):393-404.
2012: Britt-Marie Swahn; Stefan von Berg; Margareta Ek; Johanna Fälting; Biljana Georgievska; Susanne Gustavsson; Jörg Holenz; Jacob Kihlström; Karin Kolmodin; Johan Lindström; Jan Neelissen; Lise-Lotte Olsson; Niklas Plobeck; Didier Rotticci; Fernando Sehgelmeble; Marie Sundström; Stefan Berg
Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacy.
Bioorganic & medicinal chemistry letters 2012;22(5):1854-9.
2011: Mickael Decressac; Biljana Georgievska; Deniz Kirik; Bengt Mattsson; Marina Romero-Ramos; Ayse Ulusoy; Anders Björklund
GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson's disease.
Brain : a journal of neurology 2011;134(Pt 8):2302-11.
2007: Kanter-Schlifke Irene; Biljana Georgievska; Deniz Kirik; Merab Kokaia
Brain area, age and viral vector-specific glial cell-line-derived neurotrophic factor expression and transport in rat.
Neuroreport 2007;18(9):845-50.
2007: Kanter-Schlifke Irene; Biljana Georgievska; Deniz Kirik; Merab Kokaia
Seizure suppression by GDNF gene therapy in animal models of epilepsy.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(6):1106-13.
2006: Christian Winkler; Biljana Georgievska; Thomas Carlsson; Benjamin Lacar; Deniz Kirik
Continuous exposure to glial cell line-derived neurotrophic factor to mature dopaminergic transplants impairs the graft's ability to improve spontaneous motor behavior in parkinsonian rats.
Neuroscience 2006;141(1):521-31.
2006: Johan Jakobsson; T Tolstrup Nielsen; Karin Staflin; Biljana Georgievska; Cecilia Lundberg
Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors.
Gene therapy 2006;13(12):966-73.
2006: Sophie Pezet; Agnieszka Krzyzanowska; Liang-Fong Wong; John Grist; Nicholas D Mazarakis; Biljana Georgievska; Stephen McMahon
Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(6):1101-9.
2005: Cecilia Ericson; Biljana Georgievska; Cecilia Lundberg
Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease.
The European journal of neuroscience 2005;22(11):2755-64.
2005: Andisheh Eslamboli; Biljana Georgievska; Rosalind M Ridley; Harry F Baker; Nicholas Muzyczka; Corinna Burger; Ronald J Mandel; Lucy E Annett; Deniz Kirik
Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(4):769-77.
2004: Biljana Georgievska; Thomas Carlsson; Benjamin Lacar; Christian Winkler; Deniz Kirik
Dissociation between short-term increased graft survival and long-term functional improvements in Parkinsonian rats overexpressing glial cell line-derived neurotrophic factor.
The European journal of neuroscience 2004;20(11):3121-30.
2004: Biljana Georgievska; Johan Jakobsson; Elisabeth Persson; Cecilia Ericson; Deniz Kirik; Cecilia Lundberg
Regulated delivery of glial cell line-derived neurotrophic factor into rat striatum, using a tetracycline-dependent lentiviral vector.
Human gene therapy 2004;15(10):934-44.
2004: Biljana Georgievska; Deniz Kirik; Anders Björklund
Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(29):6437-45.
2004: Johan Jakobsson; Biljana Georgievska; Cecilia Ericson; Cecilia Lundberg
Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector.
The European journal of neuroscience 2004;19(3):761-5.
2004: Deniz Kirik; Biljana Georgievska; Anders Björklund
Localized striatal delivery of GDNF as a treatment for Parkinson disease.
Nature neuroscience 2004;7(2):105-10.
2003: Carl Rosenblad; Biljana Georgievska; Deniz Kirik
Long-term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system.
The European journal of neuroscience 2003;17(2):260-70.
2002: Biljana Georgievska; Deniz Kirik; Anders Björklund
Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer.
Experimental neurology 2002;177(2):461-74.
2002: Deniz Kirik; Biljana Georgievska; Corinna Burger; Christian Winkler; Nicholas Muzyczka; Ronald J Mandel; Anders Björklund
Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of L-dopa using rAAV-mediated gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4708-13.
2002: Biljana Georgievska; Deniz Kirik; Carl Rosenblad; Cecilia Lundberg; Anders Björklund
Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector.
Neuroreport 2002;13(1):75-82.
2001: Deniz Kirik; Biljana Georgievska; Carl Rosenblad; Anders Björklund
Delayed infusion of GDNF promotes recovery of motor function in the partial lesion model of Parkinson's disease.
The European journal of neuroscience 2001;13(8):1589-99.
2000: Anders Björklund; Deniz Kirik; Carl Rosenblad; Biljana Georgievska; Cecilia Lundberg; Ronald J Mandel
Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model.
Brain research 2000;886(1-2):82-98.