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Katia Georgopoulos

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Rong Han; Lionel Larue; Yun-Kyoung Lee; En Li; Lorin Weiner; Hideyuki Beppu; Katia Georgopoulos; Janice L Brissette
A pair of transmembrane receptors essential for the retention and pigmentation of hair.
Nicola Harker; Anna Garefalaki; Ursula Menzel; Eleni Ktistaki; Taku Naito; Katia Georgopoulos; Dimitris Kioussis
Pre-TCR signaling and CD8 gene bivalent chromatin resolution during thymocyte development.
Toshimi Yoshida; Samuel Yao-Ming Ng; Katia Georgopoulos
Awakening lineage potential by Ikaros-mediated transcriptional priming.

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All Publications

2012: Rong Han; Lionel Larue; Yun-Kyoung Lee; En Li; Lorin Weiner; Hideyuki Beppu; Katia Georgopoulos; Janice L Brissette
A pair of transmembrane receptors essential for the retention and pigmentation of hair.
Genesis (New York, N.Y. : 2000) 2012;50(11):783-800.
2011: Nicola Harker; Anna Garefalaki; Ursula Menzel; Eleni Ktistaki; Taku Naito; Katia Georgopoulos; Dimitris Kioussis
Pre-TCR signaling and CD8 gene bivalent chromatin resolution during thymocyte development.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(11):6368-77.
2010: Toshimi Yoshida; Samuel Yao-Ming Ng; Katia Georgopoulos
Awakening lineage potential by Ikaros-mediated transcriptional priming.
Current opinion in immunology 2010;22(2):154-60.
2009: Samuel Yao-Ming Ng; Toshimi Yoshida; Jiangwen Zhang; Katia Georgopoulos
Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells.
Immunity 2009;30(4):493-507.
2008: Toshimi Yoshida; Idit Hazan; Jiangwen Zhang; Samuel Y Ng; Taku Naito; Hugo J Snippert; Eric Heller; Xiaoqing Qi; Lee N Lawton; Christine J Williams; Katia Georgopoulos
The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation.
Genes & development 2008;22(9):1174-89.
2007: Taku Naito; Pablo Gómez-del Arco; Christine J Williams; Katia Georgopoulos
Antagonistic interactions between Ikaros and the chromatin remodeler Mi-2beta determine silencer activity and Cd4 gene expression.
Immunity 2007;27(5):723-34.
2007: Dimitris Kioussis; Katia Georgopoulos
Epigenetic flexibility underlying lineage choices in the adaptive immune system.
Science (New York, N.Y.) 2007;317(5838):620-2.
2007: Mariko Kashiwagi; Bruce A Morgan; Katia Georgopoulos
The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny.
Development (Cambridge, England) 2007;134(8):1571-82.
2007: Samuel Yao-Ming Ng; Toshimi Yoshida; Katia Georgopoulos
Ikaros and chromatin regulation in early hematopoiesis.
Current opinion in immunology 2007;19(2):116-22.
2006: Toshimi Yoshida; Samuel Yao-Ming Ng; Juan Carlos Zuniga-Pflucker; Katia Georgopoulos
Early hematopoietic lineage restrictions directed by Ikaros.
Nature immunology 2006;7(4):382-91.
2006: Yoshihide Ueda; Masaki Okano; Christine Williams; Taiping Chen; Katia Georgopoulos; En Li
Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome.
Development (Cambridge, England) 2006;133(6):1183-92.
2005: Emerson Liu; Sumita Sinha; Christine Williams; Marcoli Cyrille; Eric Heller; Scott B Snapper; Katia Georgopoulos; René St-Arnaud; Thomas Force; Shoukat Dedhar; Robert E Gerszten
Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival.
Molecular and cellular biology 2005;25(24):11145-55.
2005: Pablo Gómez-del Arco; Joseph Koipally; Katia Georgopoulos
Ikaros SUMOylation: switching out of repression.
Molecular and cellular biology 2005;25(7):2688-97.
2004: Christine J Williams; Taku Naito; Pablo Gómez-Del Arco; John R Seavitt; Susan M Cashman; Beverly De Souza; Xiaoqing Qi; Piper Keables; Ulrich H von Andrian; Katia Georgopoulos
The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development.
Immunity 2004;20(6):719-33.
2004: Pablo Gómez-del Arco; Kazushige Maki; Katia Georgopoulos
Phosphorylation controls Ikaros's ability to negatively regulate the G(1)-S transition.
Molecular and cellular biology 2004;24(7):2797-807.
2004: Marta Cortés; Katia Georgopoulos
Aiolos is required for the generation of high affinity bone marrow plasma cells responsible for long-term immunity.
The Journal of experimental medicine 2004;199(2):209-19.
2003: Christoph Kaufmann; Toshimi Yoshida; Elizabeth A Perotti; Esther Landhuis; Paul Wu; Katia Georgopoulos
A complex network of regulatory elements in Ikaros and their activity during hemo-lymphopoiesis.
The EMBO journal 2003;22(9):2211-23.
2002: Nicola Harker; Taku Naito; Marta Cortes; Arnd Hostert; Sandra Hirschberg; Mauro Tolaini; Kathleen Roderick; Katia Georgopoulos; Dimitris Kioussis
The CD8alpha gene locus is regulated by the Ikaros family of proteins.
Molecular cell 2002;10(6):1403-15.
2002: Joseph Koipally; Katia Georgopoulos
A molecular dissection of the repression circuitry of Ikaros.
The Journal of biological chemistry 2002;277(31):27697-705.
2002: Joseph Koipally; Katia Georgopoulos
Ikaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repression.
The Journal of biological chemistry 2002;277(26):23143-9.
2002: Joseph Koipally; Eric Heller; John R Seavitt; Katia Georgopoulos
Unconventional potentiation of gene expression by Ikaros.
The Journal of biological chemistry 2002;277(15):13007-15.
2001: Annaiah Cariappa; M Tang; C Parng; E Nebelitskiy; M Carroll; Katia Georgopoulos; Shiv Pillai
The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21.
Immunity 2001;14(5):603-15.
2001: Li Wu; Stephane Vandenabeele; Katia Georgopoulos
Derivation of dendritic cells from myeloid and lymphoid precursors.
International reviews of immunology 2001;20(1):117-35.
2000: Joseph Koipally; Katia Georgopoulos
Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity.
The Journal of biological chemistry 2000;275(26):19594-602.
1999: A Nichogiannopoulou; M Trevisan; S Neben; C Friedrich; Katia Georgopoulos
Defects in hemopoietic stem cell activity in Ikaros mutant mice.
The Journal of experimental medicine 1999;190(9):1201-14.
1999: Susan M. Winandy; L Wu; J H Wang; Katia Georgopoulos
Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros.
The Journal of experimental medicine 1999;190(8):1039-48.
1999: Joseph Koipally; A Renold; J Kim; Katia Georgopoulos
Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes.
The EMBO journal 1999;18(11):3090-100.
1999: Katia Georgopoulos
Gene regulation and cancer. AACR meeting review, the Homestead, Hot Springs, VA, USA, 14-18 October 1998.
Biochimica et biophysica acta 1999;1423(3):R75-9.
1999: M Cortes; E Wong; Joseph Koipally; Katia Georgopoulos
Control of lymphocyte development by the Ikaros gene family.
Current opinion in immunology 1999;11(2):167-71.
1999: J Kim; Saïd Sif; B Jones; A Jackson; Joseph Koipally; Eric Heller; Susan M. Winandy; A Viel; A Sawyer; T Ikeda; R Kingston; Katia Georgopoulos
Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.
Immunity 1999;10(3):345-55.
1999: N Avitahl; Susan M. Winandy; C Friedrich; B Jones; Y Ge; Katia Georgopoulos
Ikaros sets thresholds for T cell activation and regulates chromosome propagation.
Immunity 1999;10(3):333-43.
1999: Joseph Koipally; J Kim; B Jones; A Jackson; N Avitahl; Susan M. Winandy; M Trevisan; A Nichogiannopoulou; C Kelley; Katia Georgopoulos
Ikaros chromatin remodeling complexes in the control of differentiation of the hemo-lymphoid system.
Cold Spring Harbor symposia on quantitative biology 1999;64():79-86.
1998: J H Wang; N Avitahl; Annaiah Cariappa; C Friedrich; T Ikeda; A Renold; K Andrikopoulos; L Liang; Shiv Pillai; Bruce A Morgan; Katia Georgopoulos
Aiolos regulates B cell activation and maturation to effector state.
Immunity 1998;9(4):543-53.
1998: C M Kelley; T Ikeda; Joseph Koipally; N Avitahl; L Wu; Katia Georgopoulos; Bruce A Morgan
Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors.
Current biology : CB 1998;8(9):508-15.
1998: A Nichogiannopoulou; M Trevisan; C Friedrich; Katia Georgopoulos
Ikaros in hemopoietic lineage determination and homeostasis.
Seminars in immunology 1998;10(2):119-25.
1997: Li Wu; A Nichogiannopoulou; Ken Shortman; Katia Georgopoulos
Cell-autonomous defects in dendritic cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage.
Immunity 1997;7(4):483-92.
1997: B Morgan; L Sun; N Avitahl; K Andrikopoulos; T Ikeda; E Gonzales; P Wu; S Neben; Katia Georgopoulos
Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation.
The EMBO journal 1997;16(8):2004-13.
1997: Katia Georgopoulos
Transcription factors required for lymphoid lineage commitment.
Current opinion in immunology 1997;9(2):222-7.
1997: Katia Georgopoulos; Susan M. Winandy; N Avitahl
The role of the Ikaros gene in lymphocyte development and homeostasis.
Annual review of immunology 1997;15():155-76.
1996: J H Wang; A Nichogiannopoulou; Li Wu; L Sun; A H Sharpe; M Bigby; Katia Georgopoulos
Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation.
Immunity 1996;5(6):537-49.
1996: L Sun; A Liu; Katia Georgopoulos
Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development.
The EMBO journal 1996;15(19):5358-69.
1996: A Molnár; P Wu; D A Largespada; A Vortkamp; S Scherer; N G Copeland; N A Jenkins; G Bruns; Katia Georgopoulos
The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):585-92.
1995: Susan M. Winandy; P Wu; Katia Georgopoulos
A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma.
Cell 1995;83(2):289-99.
1994: A Molnár; Katia Georgopoulos
The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins.
Molecular and cellular biology 1994;14(12):8292-303.
1994: Katia Georgopoulos; M Bigby; J H Wang; A Molnar; P Wu; Susan M. Winandy; A Sharpe
The Ikaros gene is required for the development of all lymphoid lineages.
Cell 1994;79(1):143-56.
1992: Katia Georgopoulos; David D Moore; B Derfler
Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment.
Science (New York, N.Y.) 1992;258(5083):808-12.
1992: Katia Georgopoulos; B A Morgan; David D Moore
Functionally distinct isoforms of the CRE-BP DNA-binding protein mediate activity of a T-cell-specific enhancer.
Molecular and cellular biology 1992;12(2):747-57.