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William Gerald

Research Profile

Physiology

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Publications

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Janeen Azare; Marjan Berishaj; Hikmat Al-Ahmadie; Qing Chang; Ashley Doane; William Gerald; Maryam Hassimi; Kenneth Leslie; David Lyden; Kevin Mark; Jennifer Nnoli; Mary Stracke; Agnes Viale; Jacqueline F Bromberg
Stat3 mediates expression of autotaxin in breast cancer.
Udo Rudloff; Umesh Bhanot; William Gerald; David S Klimstra; William R Jarnagin; Murray F Brennan; Peter J Allen
Biobanking of human pancreas cancer tissue: impact of ex-vivo procurement times on RNA quality.
Kevin Kalinsky; Lindsay M Jacks; Adriana Heguy; Sujata M Patil; Marija Drobnjak; Umeshkumar K Bhanot; Cyrus V Hedvat; Tiffany A Traina; David B Solit; William Gerald; Mary Ellen Moynahan
PIK3CA mutation associates with improved outcome in breast cancer.

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All Publications

2011: Janeen Azare; Marjan Berishaj; Hikmat Al-Ahmadie; Qing Chang; Ashley Doane; William Gerald; Maryam Hassimi; Kenneth Leslie; David Lyden; Kevin Mark; Jennifer Nnoli; Mary Stracke; Agnes Viale; Jacqueline F Bromberg
Stat3 mediates expression of autotaxin in breast cancer.
PloS one 2011;6(11):e27851.
2010: Udo Rudloff; Umesh Bhanot; William Gerald; David S Klimstra; William R Jarnagin; Murray F Brennan; Peter J Allen
Biobanking of human pancreas cancer tissue: impact of ex-vivo procurement times on RNA quality.
Annals of surgical oncology 2010;17(8):2229-36.
2009: Kevin Kalinsky; Lindsay M Jacks; Adriana Heguy; Sujata M Patil; Marija Drobnjak; Umeshkumar K Bhanot; Cyrus V Hedvat; Tiffany A Traina; David B Solit; William Gerald; Mary Ellen Moynahan
PIK3CA mutation associates with improved outcome in breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(16):5049-59.
2009: Dhananjay A Chitale; Yixuan Gong; B S Taylor; S Broderick; Cameron Brennan; Romel Somwar; B Golas; Liang Wang; N Motoi; J Szoke; J M Reinersman; J Major; Chris Sander; Venkatraman E Seshan; Maureen F Zakowski; Valerie W Rusch; William Pao; William Gerald; Marc Ladanyi
An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors.
Oncogene 2009;28(31):2773-83.
2009: Xiang H-F Zhang; Qiongqing Wang; William Gerald; Clifford Hudis; Larry Norton; Marcel Smid; John A Foekens; Joan Massagué
Latent bone metastasis in breast cancer tied to Src-dependent survival signals.
Cancer cell 2009;16(1):67-78.
2009: Brett S Carver; Jennifer Tran; Anuradha Gopalan; Zhenbang Chen; Safa Shaikh; Arkaitz Carracedo; Andrea Alimonti; Caterina Nardella; Shohreh Varmeh; Peter T Scardino; Carlos Cordon-Cardo; William Gerald; Pier Paolo Pandolfi
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.
Nature genetics 2009;41(5):619-24.
2009: Alex J Rai; Rashmi M Kamath; William Gerald; Martin Fleisher
Analytical validation of the GeXP analyzer and design of a workflow for cancer-biomarker discovery using multiplexed gene-expression profiling.
Analytical and bioanalytical chemistry 2009;393(5):1505-11.
2009: Brett S Carver; Jennifer Tran; Zhenbang Chen; Arkaitz Carracedo-Perez; Andrea Alimonti; Caterina Nardella; Anuradha Gopalan; Peter T Scardino; Carlos Cordon-Cardo; William Gerald; Pier Paolo Pandolfi
ETS rearrangements and prostate cancer initiation.
Nature 2009;457(7231):E1; discussion E2-3.
2008: Irene Y Cheung; Yi Feng; William Gerald; Nai-Kong V Cheung
Exploiting gene expression profiling to identify novel minimal residual disease markers of neuroblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(21):7020-7.
2008: Ann Forslund; Zhaoshi Zeng; Li-Xuan Qin; Shoshana Rosenberg; MacKevin Ndubuisi; Hanna Pincas; William Gerald; Daniel A Notterman; Francis Barany; Philip B Paty
MDM2 gene amplification is correlated to tumor progression but not to the presence of SNP309 or TP53 mutational status in primary colorectal cancers.
Molecular cancer research : MCR 2008;6(2):205-11.
2007: James Bean; Cameron Brennan; Jin-Yuan Shih; Gregory J Riely; Agnes Viale; Lu Wang; Dhananjay Chitale; Noriko Motoi; Janos Szoke; Stephen Broderick; Marissa N Balak; Wen-Cheng Chang; Chong-Jen Yu; Adi F Gazdar; Harvey I Pass; Valerie W Rusch; William Gerald; Shiu-Feng Huang; Pan-Chyr Yang; Vincent A Miller; Marc Ladanyi; Chih-Hsin Yang; William Pao
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(52):20932-7.
2007: Stephen W Gilheeney; David Lyden; Shirley Sgouros; Nuno Lobo Antunes; William Gerald; Kim Kramer; Eric Lis; Paul A Meyers; Nancy Rosen; Howard T Thaler; Tanya M Trippett; Leonard H Wexler; Ira J Dunkel
A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignancies.
Pediatric blood & cancer 2007;49(3):261-5.
2007: Janeen Azare; Kenneth Leslie; Hikmat Al-Ahmadie; William Gerald; Paul H Weinreb; Shelia M Violette; Jacqueline F Bromberg
Constitutively activated Stat3 induces tumorigenesis and enhances cell motility of prostate epithelial cells through integrin beta 6.
Molecular and cellular biology 2007;27(12):4444-53.
2007: Irene Y Cheung; Yi Feng; Andrew J Vickers; William Gerald; Nai-Kong V Cheung
Cyclin D1, a novel molecular marker of minimal residual disease, in metastatic neuroblastoma.
The Journal of molecular diagnostics : JMD 2007;9(2):237-41.
2007: Matthew G Fury; Andrew J Zahalsky; Richard J Wong; Venkatraman E Seshan; Eric Lis; Lucy E Hann; Timothy B Aliff; William Gerald; Martin Fleisher; David G Pfister
A Phase II study of SU5416 in patients with advanced or recurrent head and neck cancers.
Investigational new drugs 2007;25(2):165-72.
2007: Sarah E Ferguson; William Gerald; Richard R Barakat; Dennis S Chi; Robert A Soslow
Clinicopathologic features of rhabdomyosarcoma of gynecologic origin in adults.
The American journal of surgical pathology 2007;31(3):382-9.
2006: Yu Wen; Sarah F Giardina; David Hamming; Jennifer Greenman; Emmanuel Zachariah; Manny Bacolod; Hao Liu; Jinru Shia; Peter S Amenta; Francis Barany; Philip B Paty; William Gerald; Daniel A Notterman
GROalpha is highly expressed in adenocarcinoma of the colon and down-regulates fibulin-1.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 1):5951-9.
2006: Charles J Ryan; Alex Smith; Priti Lal; Jaya M Satagopan; Victor E Reuter; Peter T Scardino; William Gerald; Howard I Scher
Persistent prostate-specific antigen expression after neoadjuvant androgen depletion: an early predictor of relapse or incomplete androgen suppression.
Urology 2006;68(4):834-9.
2006: Rohit Bhargava; Beiyun Chen; David S Klimstra; Leonard B Saltz; Cyrus V Hedvat; Laura H Tang; William Gerald; Julie T Feldstein; Philip B Paty; Jing Qin; Jinru Shia
Comparison of two antibodies for immunohistochemical evaluation of epidermal growth factor receptor expression in colorectal carcinomas, adenomas, and normal mucosa.
Cancer 2006;106(8):1857-62.
2006: Kenneth Leslie; Cynthia Lang; Geeta Devgan; Janeen Azare; Marjan Berishaj; William Gerald; Young Bae Kim; Keren Paz; James E Darnell; Chris Albanese; Toshiyuki Sakamaki; Richard G Pestell; Jacqueline F Bromberg
Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3.
Cancer research 2006;66(5):2544-52.
2005: Jinru Shia; David S Klimstra; Allan R Li; Jing Qin; Leonard B Saltz; Julie T Feldstein; MUZAFFAR M AKRAM; Ki Young Chung; Davis Yao; Philip B Paty; William Gerald; Beiyun Chen
Epidermal growth factor receptor expression and gene amplification in colorectal carcinoma: an immunohistochemical and chromogenic in situ hybridization study.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(10):1350-6.
2005: Zhenbang Chen; Lloyd C Trotman; David Shaffer; Hui-Kuan Lin; Zohar A Dotan; Masaru Niki; Jason A Koutcher; Howard I Scher; Thomas Ludwig; William Gerald; Carlos Cordon-Cardo; Pier Paolo Pandolfi
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Nature 2005;436(7051):725-30.
2005: Rohit Bhargava; Orit Oppenheimer; William Gerald; Suresh C Jhanwar; Beiyun Chen
Identification of MYCN gene amplification in neuroblastoma using chromogenic in situ hybridization (CISH): an alternative and practical method.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2005;14(2):72-6.
2004: Francis M Sirotnak; Yuhong She; Nushmia Z Khokhar; Paula Hayes; William Gerald; Howard I Scher
Microarray analysis of prostate cancer progression to reduced androgen dependence: studies in unique models contrasts early and late molecular events.
Molecular carcinogenesis 2004;41(3):150-63.
2004: Howard I Scher; Grant Buchanan; William Gerald; Lisa M Butler; Wayne D Tilley
Targeting the androgen receptor: improving outcomes for castration-resistant prostate cancer.
Endocrine-related cancer 2004;11(3):459-76.
2004: Eva Hernando; Zaher Nahlé; Gloria Juan; Elena Diaz-Rodriguez; Miguel Alaminos; Michael T Hemann; Loren Michel; Vivek Mittal; William Gerald; Robert Benezra; Scott W Lowe; Carlos Cordon-Cardo
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.
Nature 2004;430(7001):797-802.
2003: Marianna B Ruzinova; Rebecca A Schoer; William Gerald; James Egan; Pier Paolo Pandolfi; Shahin Rafii; Katia Manova-Todorova; Vivek Mittal; Robert Benezra
Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors.
Cancer cell 2003;4(4):277-89.
2003: Daniel R Nathanson; Garrett M Nash; Beiyun Chen; William Gerald; Philip B Paty
Detection of HER-2/neu gene amplification in breast cancer using a novel polymerase chain reaction/ligase detection reaction technique.
Journal of the American College of Surgeons 2003;197(3):419-25.
2003: Daniel R Nathanson; Alfred T Culliford; Jinru Shia; Beiyun Chen; Matthew D'Alessio; Zhaoshi Zeng; Garrett M Nash; William Gerald; Francis Barany; Philip B Paty
HER 2/neu expression and gene amplification in colon cancer.
International journal of cancer. Journal international du cancer 2003;105(6):796-802.
2003: Suchitra S. Acharya; Kyriakie Sarafoglou; Michael P LaQuaglia; Skyler K Lindsley; William Gerald; Norma Wollner; Charlotte Tan; Charles A Sklar
Thyroid neoplasms after therapeutic radiation for malignancies during childhood or adolescence.
Cancer 2003;97(10):2397-403.
2002: Shakeel Modak; William Gerald; Nai-Kong V Cheung
Disialoganglioside GD2 and a novel tumor antigen: potential targets for immunotherapy of desmoplastic small round cell tumor.
Medical and pediatric oncology 2002;39(6):547-51.
2002: Kotha Subbaramaiah; Larry Norton; William Gerald; Andrew J Dannenberg
Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3.
The Journal of biological chemistry 2002;277(21):18649-57.
2002: David G Pfister; John McCaffrey; Andrew J Zahalsky; Gary K Schwartz; Eric Lis; William Gerald; Andrew G Huvos; Jatin P Shah; Dennis H Kraus; Ashok R Shaha; Bhuvanesh Singh; Suzanne L Wolden; Michael J Zelefsky; Ilana Palgi
A phase II trial of bryostatin-1 in patients with metastatic or recurrent squamous cell carcinoma of the head and neck.
Investigational new drugs 2002;20(1):123-7.
2002: Maura Cosetti; Leonard H Wexler; Elizabeth Calleja; Tanya M Trippett; Michael P LaQuaglia; Andrew G Huvos; William Gerald; John Healey; Paul A Meyers; Richard Gorlick
Irinotecan for pediatric solid tumors: the Memorial Sloan-Kettering experience.
Journal of pediatric hematology/oncology 2002;24(2):101-5.
2001: Jaume Mora; Nai-Kong V Cheung; Lieping Chen; Jing Qin; William Gerald
Loss of heterozygosity at 19q13.3 is associated with locally aggressive neuroblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(5):1358-61.
2001: Loren S Michel; Vasco Liberal; A Chatterjee; R Kirchwegger; Boris Pasche; William Gerald; Max Dobles; Peter K Sorger; Vundavalli Murty; Robert Benezra
MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells.
Nature 2001;409(6818):355-9.
2001: Jaume Mora; Nai-Kong V Cheung; Lieping Chen; Jing Qin; William Gerald
Survival analysis of clinical, pathologic, and genetic features in neuroblastoma presenting as locoregional disease.
Cancer 2001;91(2):435-42.
2001: Nai-Kong V Cheung; Brian H Kushner; Michael P LaQuaglia; Kim Kramer; SV Gollamudi; Glenn Heller; William Gerald; S Yeh; Ronald Finn; Steven M Larson; David Wuest; M Byrnes; E Dantis; Jaume Mora; Irene Y Cheung; NS Rosenfield; Sara Abramson; Richard J O'Reilly
N7: a novel multi-modality therapy of high risk neuroblastoma (NB) in children diagnosed over 1 year of age.
Medical and pediatric oncology 2001;36(1):227-30.
1999: V Adsay; J Cheng; Edward A Athanasian; William Gerald; Juan Rosai
Primary desmoplastic small cell tumor of soft tissues and bone of the hand.
The American journal of surgical pathology 1999;23(11):1408-13.
1999: David Lyden; A Z Young; David Zagzag; W Yan; William Gerald; Richard J O'Reilly; B L Bader; R O Hynes; Y Zhuang; Katia Manova-Todorova; Robert Benezra
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts.
Nature 1999;401(6754):670-7.
1998: Nai-Kong V Cheung; Brian H Kushner; Irene Y Cheung; Kim Kramer; A Canete; William Gerald; M A Bonilla; Ronald Finn; S J Yeh; Steven M Larson
Anti-G(D2) antibody treatment of minimal residual stage 4 neuroblastoma diagnosed at more than 1 year of age.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(9):3053-60.
1997: NC Saenz; F Ghavimi; William Gerald; SV Gollamudi; Michael P LaQuaglia
Chest wall rhabdomyosarcoma.
Cancer 1997;80(8):1513-7.
1997: Nai-Kong V Cheung; Brian H Kushner; Michael P LaQuaglia; Kim Kramer; Peter F Ambros; I Ambros; Marc Ladanyi; J Eddy; M A Bonilla; William Gerald
Survival from non-stage 4 neuroblastoma without cytotoxic therapy: an analysis of clinical and biological markers.
European journal of cancer (Oxford, England : 1990) 1997;33(12):2117-20.
1997: Kim Kramer; William Gerald; L LeSauteur; H Uri Saragovi; Nai-Kong V Cheung
Monoclonal antibody to human Trk-A: diagnostic and therapeutic potential in neuroblastoma.
European journal of cancer (Oxford, England : 1990) 1997;33(12):2090-1.
1997: E S Hwang; William Gerald; Norma Wollner; Paul A Meyers; Michael P LaQuaglia
Leiomyosarcoma in childhood and adolescence.
Annals of surgical oncology 1997;4(3):223-7.