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James Gern

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Monica L Gavala; Hiba Bashir; James E Gern
Virus/Allergen interactions in asthma.
Minal Calışkan; Gaixin Du; James E Gern; Daniel J Jackson; Eskil Kreiner-Møller; Robert F Lemanske; Dan L Nicolae; Hans Bisgaard; Yury A Bochkov; Klaus Bønnelykke; Michelle M Stein; Carole Ober
Rhinovirus wheezing illness and genetic risk of childhood-onset asthma.
Shamaila Ashraf; Yury A Bochkov; Rebecca Brockman-Schneider; Thomas R Pasic; James E Gern
Biological characteristics and propagation of human rhinovirus-C in differentiated sinus epithelial cells.

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2013: Monica L Gavala; Hiba Bashir; James E Gern
Virus/Allergen interactions in asthma.
Current allergy and asthma reports 2013;13(3):298-307.
2013: Minal Calışkan; Gaixin Du; James E Gern; Daniel J Jackson; Eskil Kreiner-Møller; Robert F Lemanske; Dan L Nicolae; Hans Bisgaard; Yury A Bochkov; Klaus Bønnelykke; Michelle M Stein; Carole Ober
Rhinovirus wheezing illness and genetic risk of childhood-onset asthma.
The New England journal of medicine 2013;368(15):1398-407.
2013: Shamaila Ashraf; Yury A Bochkov; Rebecca Brockman-Schneider; Thomas R Pasic; James E Gern
Biological characteristics and propagation of human rhinovirus-C in differentiated sinus epithelial cells.
Virology 2013;436(1):143-9.
2013: D J Stoltz; Christopher J Tisler; Michael D Evans; Ronald E Gangnon; James E Gern; D J Jackson; Robert F Lemanske
Specific patterns of allergic sensitization in early childhood and asthma & rhinitis risk.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2013;43(2):233-41.
2013: Robert V Cadman; Michael D Evans; James E Gern; Daniel J Jackson; Robert F Lemanske; Ronald L Sorkness; Sean B Fain
Pulmonary 3He magnetic resonance imaging of childhood asthma.
The Journal of allergy and clinical immunology 2013;131(2):369-76.e1-5.
2013: Anne Marie Singh; Christopher J Tisler; Kristjan Burmeister; Paul Dahlberg; Douglas F Dasilva; Michael D Evans; Ronald Gangnon; James E Gern; Robert F Lemanske; Tressa Pappas; Kathy A Roberg; Lisa Salazar; Christine M Seroogy
Inhaled corticosteroid use is associated with increased circulating T regulatory cells in children with asthma.
Clinical and molecular allergy : CMA 2013;11(1):1.
2012: James E Gern; Katy F Jaffee; Carin Lamm; Robert F Lemanske; Tressa Pappas; Alkis Togias; Marina Tuzova; Cynthia M Visness; Robert A Wood; Gordon R Bloomberg; William W Cruikshank; Wai Ming Lee
Comparison of the etiology of viral respiratory illnesses in inner-city and suburban infants.
The Journal of infectious diseases 2012;206(9):1342-9.
2012: Kei E Fujimura; James E Gern; Shoko Iwai; Christine C Johnson; Suzanne Kennedy; Henry Lynn; Elizabeth C Matsui; Herman Mitchell; Marcus Rauch; Alkis Togias; Homer A Boushey; Agustin Calatroni; Susan V Lynch
Development of a standardized approach for environmental microbiota investigations related to asthma development in children.
Journal of microbiological methods 2012;91(2):231-9.
2012: Douglas F McMahon; Victoria Rajamanickam; Lisa Salazar; Ronald Gangnon; James E Gern
Do asthma symptoms lag behind cold symptoms in a viral illness?
The Journal of allergy and clinical immunology 2012;130(4):990-1.
2012: Sandy R Durrani; Ronald E Gangnon; James E Gern; Michelle A Gill; Robert F Lemanske; Daniel J Montville; Allison S Pratt; Victoria Rajamanickam; Sanjukta Sahu; Mark K DeVries; Daniel J Jackson
Innate immune responses to rhinovirus are reduced by the high-affinity IgE receptor in allergic asthmatic children.
The Journal of allergy and clinical immunology 2012;130(2):489-95.
2012: David M Manthei; Christopher J Tisler; Michael D Evans; Ronald E Gangnon; James E Gern; Daniel J Jackson; Robert F Lemanske; Loren C Denlinger
Protection from asthma in a high-risk birth cohort by attenuated P2X(7) function.
The Journal of allergy and clinical immunology 2012;130(2):496-502.
2012: Kirsten M Kloepfer; Wai Ming Lee; Robert F Lemanske; Guiyan Liu; Jaime P Olenec; Kathy A Roberg; Rose F Vrtis; Michael D Evans; Ronald E Gangnon; James E Gern
Increased H1N1 infection rate in children with asthma.
American journal of respiratory and critical care medicine 2012;185(12):1275-9.
2012: Yury A Bochkov; James E Gern
Clinical and molecular features of human rhinovirus C.
Microbes and infection / Institut Pasteur 2012;14(6):485-94.
2012: Kaharu Sumino; Jennifer Tucker; Cynthia M Visness; Gordon R Bloomberg; James E Gern; Katy F Jaffee; Muhammad Shahab; Michael J Holtzman
Antiviral IFN-γ responses of monocytes at birth predict respiratory tract illness in the first year of life.
The Journal of allergy and clinical immunology 2012;129(5):1267-1273.e1.
2012: Amy L O'Brian; Robert F Lemanske; Michael D Evans; Ronald E Gangnon; James E Gern; Daniel J Jackson
Recurrent severe exacerbations in early life and reduced lung function at school age.
The Journal of allergy and clinical immunology 2012;129(4):1162-4.
2012: R M McLoughlin; B Ruiz-Perez; M Tuzova; Cynthia M Visness; P K Wallace; G R Bloomberg; A Calatroni; W W Cruikshank; James E Gern; M Kattan; Howard M Lederman; Ngoc P Ly; Diane R Gold
Longitudinal relationship of early life immunomodulatory T cell phenotype and function to development of allergic sensitization in an urban cohort.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2012;42(3):392-404.
2012: William W Busse; James E Gern
Asthma and pregnancy: do they give clues to abnormal antiviral activity?
Thorax 2012;67(3):189-90.
2012: Daniel J Jackson; Wai-Ming Lee; Michael D Evans; Ronald E Gangnon; James E Gern; Tressa E Pappas; Christopher J Tisler; Robert F Lemanske
Evidence for a causal relationship between allergic sensitization and rhinovirus wheezing in early life.
American journal of respiratory and critical care medicine 2012;185(3):281-5.
2012: Louis A Rosenthal; Renee J Szakaly; Yina Xing; Svetlana P Amineva; James E Gern; Marchel R Hill; Ann C Palmenberg; Ronald L Sorkness
Lower respiratory tract infection induced by a genetically modified picornavirus in its natural murine host.
PloS one 2012;7(2):e32061.
2011: Robert S Zeiger; Leonard B Bacharier; Elizabeth Bade; Avraham Beigelman; Susan J Boehmer; Vernon M Chinchilli; Ronina A Covar; Noah J Friedman; James E Gern; Theresa W Guilbert; Daniel J Jackson; H William Kelly; Robert F Lemanske; Jonathan Malka-Rais; Fernando D Martinez; David T Mauger; Michael H Mellon; Wayne J Morgan; Hengameh H Raissy; Michael Schatz; Christine A Sorkness; Robert C Strunk; Stanley J Szefler; Lynn M Taussig
Daily or intermittent budesonide in preschool children with recurrent wheezing.
The New England journal of medicine 2011;365(21):1990-2001.
2011: Svetlana P Amineva; James E Gern; Aleksey G Aminev; Ann C Palmenberg
Comparison of rhinovirus A infection in human primary epithelial and HeLa cells.
The Journal of general virology 2011;92(Pt 11):2549-57.
2011: Theresa W Guilbert; Daniel J Jackson; Tressa E Pappas; Kathy A Roberg; Anne Marie Singh; Elizabeth L Anderson; Ryan Burton; Zoran Danov; Michael D Evans; Ronald E Gangnon; James E Gern; Robert F Lemanske
Decreased lung function after preschool wheezing rhinovirus illnesses in children at risk to develop asthma.
The Journal of allergy and clinical immunology 2011;128(3):532-8.e1-10.
2011: Dagan A Loisel; Zheng Tan; Christopher J Tisler; Michael D Evans; Ronald E Gangnon; James E Gern; Daniel J Jackson; Robert F Lemanske; Carole Ober
IFNG genotype and sex interact to influence the risk of childhood asthma.
The Journal of allergy and clinical immunology 2011;128(3):524-31.
2011: Monica L Gavala; Paul J Bertics; James E Gern
Rhinoviruses, allergic inflammation, and asthma.
Immunological reviews 2011;242(1):69-90.
2011: Yury A Bochkov; Ann C Palmenberg; Wai-Ming Lee; Jennifer A Rathe; Svetlana P Amineva; Xin Sun; Thomas R Pasic; Nizar N Jarjour; Stephen B Liggett; James E Gern
Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C.
Nature medicine 2011;17(5):627-32.
2011: Robert A Wood; Gordon R Bloomberg; Meyer Kattan; Kathleen Conroy; Megan T Sandel; Amy Dresen; Peter J Gergen; Diane R Gold; John C Schwarz; Cynthia M Visness; James E Gern
Relationships among environmental exposures, cord blood cytokine responses, allergy, and wheeze at 1 year of age in an inner-city birth cohort (Urban Environment and Childhood Asthma study).
The Journal of allergy and clinical immunology 2011;127(4):913-9.e1-6.
2011: William W Busse; Wayne J Morgan; Peter J Gergen; Herman E Mitchell; James E Gern; Andrew H Liu; Rebecca S Gruchalla; Meyer Kattan; Stephen J Teach; Jacqueline A Pongracic; James F Chmiel; Suzanne F Steinbach; Agustin Calatroni; Alkis Togias; Katherine M Thompson; Stanley J Szefler; Christine A Sorkness
Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children.
The New England journal of medicine 2011;364(11):1005-15.
2011: Kirsten M Kloepfer; Jennifer P DeMore; Rose F Vrtis; Cheri A Swenson; Katie L Gaworski; Jack A Bork; Michael D Evans; James E Gern
Effects of montelukast on patients with asthma after experimental inoculation with human rhinovirus 16.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2011;106(3):252-7.
2010: Zhumin Zhang; HuiChuan J Lai; Kathy A Roberg; Ronald E Gangnon; Michael D Evans; Elizabeth L Anderson; Tressa E Pappas; Douglas F Dasilva; Christopher J Tisler; Lisa P Salazar; James E Gern; Robert F Lemanske
Early childhood weight status in relation to asthma development in high-risk children.
The Journal of allergy and clinical immunology 2010;126(6):1157-62.
2010: Kirsten M Kloepfer; James E Gern
Virus/allergen interactions and exacerbations of asthma.
Immunology and allergy clinics of North America 2010;30(4):553-63, vii.
2010: William W Busse; Robert F Lemanske; James E Gern
Role of viral respiratory infections in asthma and asthma exacerbations.
Lancet 2010;376(9743):826-34.
2010: Michael E Possin; Stephanie Morgan; Douglas F Dasilva; Christopher J Tisler; Tressa E Pappas; Kathy A Roberg; Elizabeth Anderson; Michael D Evans; Ronald E Gangnon; Robert F Lemanske; James E Gern
The relationships among immunoglobulin levels, allergic sensitization, and viral respiratory illnesses in early childhood.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2010;21(6):990-6.
2010: Patricia M Zook; Carolina Jordan; Bernadette Adams; Cynthia M Visness; Michelle Walter; Kathryn Pollenz; Jennette Logan; Elizabeth Tesson; Ernestine Smartt; Amy Chen; John D'Agostino; James E Gern
Retention strategies and predictors of attrition in an urban pediatric asthma study.
Clinical trials (London, England) 2010;7(4):400-10.
2010: N L Korpi-Steiner; S M Valkenaar; Mary Ellen Bates; Michael D Evans; James E Gern; Paul J Bertics
Human monocytic cells direct the robust release of CXCL10 by bronchial epithelial cells during rhinovirus infection.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2010;40(8):1203-13.
2010: Rosalind J Wright; Cynthia M Visness; Agustin Calatroni; Mitchell H Grayson; Diane R Gold; Megan T Sandel; Aviva Lee-Parritz; Robert A Wood; Meyer Kattan; Gordon R Bloomberg; Melissa Burger; Alkis Togias; Frank R Witter; Rhoda S Sperling; Yoel Sadovsky; James E Gern
Prenatal maternal stress and cord blood innate and adaptive cytokine responses in an inner-city cohort.
American journal of respiratory and critical care medicine 2010;182(1):25-33.
2010: Louis A Rosenthal; Pedro C Avila; Peter W Heymann; Richard J Martin; E Kathryn Miller; Nikolaos G Papadopoulos; R Stokes Peebles; James E Gern
Viral respiratory tract infections and asthma: the course ahead.
The Journal of allergy and clinical immunology 2010;125(6):1212-7.
2010: Jaime P Olenec; Woo Kyung Kim; Wai-Ming Lee; Fue Vang; Tressa E Pappas; Lisa E P Salazar; Michael D Evans; JM Bork; Kathy A Roberg; Robert F Lemanske; James E Gern
Weekly monitoring of children with asthma for infections and illness during common cold seasons.
The Journal of allergy and clinical immunology 2010;125(5):1001-1006.e1.
2010: James E Gern
The Urban Environment and Childhood Asthma study.
The Journal of allergy and clinical immunology 2010;125(3):545-9.
2010: Y A Bochkov; K M Hanson; S Keles; Rebecca A Brockman-Schneider; Nizar N Jarjour; James E Gern
Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma.
Mucosal immunology 2010;3(1):69-80.
2009: Diane R Gold; Gordon R Bloomberg; William W Cruikshank; Cynthia M Visness; John Schwarz; Meyer Kattan; George T O'Connor; Robert A Wood; Melissa S Burger; Rosalind J Wright; Frank R Witter; Aviva Lee-Parritz; Rhoda Sperling; Yoel Sadovsky; Alkis Togias; James E Gern
Parental characteristics, somatic fetal growth, and season of birth influence innate and adaptive cord blood cytokine responses.
The Journal of allergy and clinical immunology 2009;124(5):1078-87.
2009: Daniel J Jackson; Christine M Virnig; Ronald E Gangnon; Michael D Evans; Kathy A Roberg; Elizabeth L Anderson; Ryan M Burton; Lisa P Salazar; Douglas F Dasilva; Kathleen M Shanovich; Christopher J Tisler; James E Gern; Robert F Lemanske
Fractional exhaled nitric oxide measurements are most closely associated with allergic sensitization in school-age children.
The Journal of allergy and clinical immunology 2009;124(5):949-53.
2009: Jennifer P DeMore; Elizabeth H Weisshaar; Rose F Vrtis; Cheri A Swenson; Michael D Evans; Allison Morin; Elizabeth Hazel; Jack A Bork; Sujani Kakumanu; Ronald L Sorkness; William W Busse; James E Gern
Similar colds in subjects with allergic asthma and nonatopic subjects after inoculation with rhinovirus-16.
The Journal of allergy and clinical immunology 2009;124(2):245-52, 252.e1-3.
2009: Loren C Denlinger; Lei Shi; Arturo Guadarrama; Kathleen Schell; Dawn Green; Alison Morrin; Kirk Hogan; Ronald L Sorkness; William W Busse; James E Gern
Attenuated P2X7 pore function as a risk factor for virus-induced loss of asthma control.
American journal of respiratory and critical care medicine 2009;179(4):265-70.
2009: James E Gern
Rhinovirus and the initiation of asthma.
Current opinion in allergy and clinical immunology 2009;9(1):73-8.
2009: Louis A Rosenthal; Svetlana P Amineva; Renee J Szakaly; Robert F Lemanske; James E Gern; Ronald L Sorkness
A rat model of picornavirus-induced airway infection and inflammation.
Virology journal 2009;6():122.
2009: Ngoc P Ly; Begona Ruiz-Perez; Rachel M McLoughlin; Cynthia M Visness; Paul K Wallace; William W Cruikshank; Arthur O Tzianabos; George T O'Connor; Diane R Gold; James E Gern
Characterization of regulatory T cells in urban newborns.
Clinical and molecular allergy : CMA 2009;7():8.
2009: James E Gern; Cynthia M Visness; Peter J Gergen; Robert A Wood; Gordon R Bloomberg; George T O'Connor; Meyer Kattan; Hugh A Sampson; Frank R Witter; Megan T Sandel; Wayne Shreffler; Rosalind J Wright; Samuel J Arbes; William W Busse
The Urban Environment and Childhood Asthma (URECA) birth cohort study: design, methods, and study population.
BMC pulmonary medicine 2009;9():17.
2008: Rebecca A Brockman-Schneider; Svetlana P Amineva; Maria V Bulat; James E Gern
Serial culture of murine primary airway epithelial cells and ex vivo replication of human rhinoviruses.
Journal of immunological methods 2008;339(2):264-9.
2008: James E Gern
Viral respiratory infection and the link to asthma.
The Pediatric infectious disease journal 2008;27(10 Suppl):S97-103.
2008: Ronald L Sorkness; Guillermo Gonzalez-Fernandez; Erin E Billmeyer; Michael D Evans; James E Gern; Nizar N Jarjour
The asthma index: a continuous variable to characterize exacerbations of asthma.
The Journal of allergy and clinical immunology 2008;122(4):838-40.
2008: Daniel J Jackson; Ronald E Gangnon; Michael D Evans; Kathy A Roberg; Elizabeth L Anderson; Tressa E Pappas; Magnolia C Printz; Wai-Ming Lee; Peter A Shult; Erik Reisdorf; Kirstin T Carlson-Dakes; Lisa P Salazar; Douglas F Dasilva; Christopher J Tisler; James E Gern; Robert F Lemanske
Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children.
American journal of respiratory and critical care medicine 2008;178(7):667-72.
2008: Marc G Busch; Allen C Bateman; Gabriele A Landolt; Alexander I Karasin; Rebecca A Brockman-Schneider; James E Gern; Marulasiddappa Suresh; Christopher W Olsen
Identification of amino acids in the HA of H3 influenza viruses that determine infectivity levels in primary swine respiratory epithelial cells.
Virus research 2008;133(2):269-79.
2008: Bogdan Jakiela; Rebecca Brockman-Schneider; Svetlana Amineva; Wai-Ming Lee; James E Gern
Basal cells of differentiated bronchial epithelium are more susceptible to rhinovirus infection.
American journal of respiratory cell and molecular biology 2008;38(5):517-23.
2008: Carole Ober; Zheng Tan; Ying Sun; Jennifer D Possick; Lin Pan; Raluca Nicolae; Sadie Radford; Rodney R Parry; Andrea Heinzmann; Klaus A Deichmann; Lucille A Lester; James E Gern; Robert F Lemanske; Dan L Nicolae; Jack A Elias; Geoffrey L Chupp
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
The New England journal of medicine 2008;358(16):1682-91.
2008: K T Sullivan Dillie; Christopher J Tisler; Douglas F Dasilva; T E Pappas; Kathy A Roberg; Kirstin T Carlson-Dakes; Michael D Evans; Louis A Rosenthal; Ronald E Gangnon; James E Gern; Robert F Lemanske
The influence of processing factors and non-atopy-related maternal and neonate characteristics on yield and cytokine responses of cord blood mononuclear cells.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2008;38(2):298-304.
2008: James E Gern; C K Stone; M Nakano; Douglas B Muchmore; Amparo de la Peña; S Park; A Suri; F Tibaldi; D Soon; William W Busse
Effect of upper respiratory tract infection on AIR inhaled insulin pharmacokinetics and glucodynamics in healthy subjects.
Clinical pharmacology and therapeutics 2008;83(2):307-11.
2007: David J Marshall; Erik Reisdorf; Gerda Harms; Edward L Beaty; Michael J Moser; Wai-Ming Lee; James E Gern; Frederick S. Nolte; Peter A Shult; James R Prudent
Evaluation of a multiplexed PCR assay for detection of respiratory viral pathogens in a public health laboratory setting.
Journal of clinical microbiology 2007;45(12):3875-82.
2007: Zheng Tan; Glenn Randall; Jihua Fan; Blanca Camoretti-Mercado; Rebecca A Brockman-Schneider; Lin Pan; Julian Solway; James E Gern; Robert F Lemanske; Dan L Nicolae; Carole Ober
Allele-specific targeting of microRNAs to HLA-G and risk of asthma.
American journal of human genetics 2007;81(4):829-34.
2007: Jeremy D Bufford; James E Gern
Early exposure to pets: good or bad?
Current allergy and asthma reports 2007;7(5):375-82.
2007: Wai-Ming Lee; Kristine A Grindle; Tressa Pappas; David J Marshall; Michael J Moser; Edward L Beaty; Peter A Shult; James R Prudent; James E Gern
High-throughput, sensitive, and accurate multiplex PCR-microsphere flow cytometry system for large-scale comprehensive detection of respiratory viruses.
Journal of clinical microbiology 2007;45(8):2626-34.
2007: Tuomas Jartti; Kristjan A Burmeister; Christine M Seroogy; Martha L Jennens-Clough; Christopher J Tisler; Lisa P Salazar; Douglas F Dasilva; Michael D Evans; Rose F Vrtis; Paul K Wallace; Begona Ruiz-Perez; Ronald E Gangnon; Robert F Lemanske; James E Gern
Association between CD4(+)CD25(high) T cells and atopy in children.
The Journal of allergy and clinical immunology 2007;120(1):177-83.
2007: Emma E Thompson; Lin Pan; Irina Ostrovnaya; Lauren A Weiss; James E Gern; Robert F Lemanske; Dan L Nicolae; Carole Ober
Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life.
The Journal of allergy and clinical immunology 2007;119(6):1423-9.
2007: James E Gern; Anne G Mosser; Cheri A Swenson; Paul J Rennie; R James England; Jacqueline Shaffer; Haruko Mizoguchi
Inhibition of rhinovirus replication in vitro and in vivo by acid-buffered saline.
The Journal of infectious diseases 2007;195(8):1137-43.
2007: Anne Marie Singh; Paul E Moore; James E Gern; Robert F Lemanske; Tina V Hartert
Bronchiolitis to asthma: a review and call for studies of gene-virus interactions in asthma causation.
American journal of respiratory and critical care medicine 2007;175(2):108-19.
2007: Wai-Ming Lee; Christin Kiesner; Tressa Pappas; Iris Lee; Kristine A Grindle; Tuomas Jartti; Bogdan Jakiela; Robert F Lemanske; Peter A Shult; James E Gern
A diverse group of previously unrecognized human rhinoviruses are common causes of respiratory illnesses in infants.
PloS one 2007;2(10):e966.
2006: Sara J Uekert; Gloria Akan; Michael D Evans; Zhanhai Li; Kathy A Roberg; Christopher J Tisler; Douglas F Dasilva; Elizabeth Anderson; Ronald E Gangnon; David B Allen; James E Gern; Robert F Lemanske
Sex-related differences in immune development and the expression of atopy in early childhood.
The Journal of allergy and clinical immunology 2006;118(6):1375-81.
2006: Svetlana P Amineva; Anne G Mosser; J J Binder; Aleksey G Aminev; Ann C Palmenberg; James E Gern
Synthesis of the allergen ovomucoid by a replicating Mengo virus.
Archives of virology 2006;151(10):1933-46.
2006: David B Lewis; James E Gern; HARRY HILL; Samuel L Friedlander; Timothy R La Pine; Robert F Lemanske; E Richard Stiehm
Newborn immunology: relevance to the clinician.
Current problems in pediatric and adolescent health care 2006;36(5):189-204.
2006: Wayne Shreffler; Cynthia M Visness; Melissa Burger; William W Cruikshank; Howard M Lederman; Maite de la Morena; Kristine Grindle; Agustin Calatroni; Frans Heeman; James E Gern
Standardization and performance evaluation of mononuclear cell cytokine secretion assays in a multicenter study.
BMC immunology 2006;7():29.
2006: James E Gern; G Daniel Brooks; Patricia Meyer; Andy Chang; Kunling Shen; Michael D Evans; Christopher J Tisler; Douglas F Dasilva; Kathy A Roberg; Lance D Mikus; Louis A Rosenthal; Carol J Kirk; Peter A Shult; Abhik Bhattacharya; Zhanhai Li; Ronald E Gangnon; Robert F Lemanske
Bidirectional interactions between viral respiratory illnesses and cytokine responses in the first year of life.
The Journal of allergy and clinical immunology 2006;117(1):72-8.
2005: Samuel L Friedlander; Daniel J Jackson; Ronald E Gangnon; Michael D Evans; Zhanhai Li; Kathy A Roberg; Elizabeth L Anderson; Kirstin T Carlson-Dakes; Kiva J Adler; Stephanie Gilbertson-White; Tressa E Pappas; Douglas F Dasilva; Christopher J Tisler; Lisa E Pleiss; Lance D Mikus; Louis A Rosenthal; Peter A Shult; Carol J Kirk; Erik Reisdorf; Sabine Hoffjan; James E Gern; Robert F Lemanske
Viral infections, cytokine dysregulation and the origins of childhood asthma and allergic diseases.
The Pediatric infectious disease journal 2005;24(11 Suppl):S170-6, discussion S174-5.
2005: Christine M Seroogy; James E Gern
The role of T regulatory cells in asthma.
The Journal of allergy and clinical immunology 2005;116(5):996-9.
2005: Robert F Lemanske; Daniel J Jackson; Ronald E Gangnon; Michael D Evans; Zhanhai Li; Peter A Shult; Carol J Kirk; Erik Reisdorf; Kathy A Roberg; Elizabeth L Anderson; Kirstin T Carlson-Dakes; Kiva J Adler; Stephanie Gilbertson-White; Tressa E Pappas; Douglas F Dasilva; Christopher J Tisler; James E Gern
Rhinovirus illnesses during infancy predict subsequent childhood wheezing.
The Journal of allergy and clinical immunology 2005;116(3):571-7.
2005: Lauren A Weiss; Lucille A Lester; James E Gern; Raoul L Wolf; Rodney Parry; Robert F Lemanske; Julian Solway; Carole Ober
Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations.
American journal of respiratory and critical care medicine 2005;172(1):67-73.
2005: Jeremy D Bufford; James E Gern
The hygiene hypothesis revisited.
Immunology and allergy clinics of North America 2005;25(2):247-62, v-vi.
2005: Elinor Simons; Mary K Schroth; James E Gern
Analysis of tracheal secretions for rhinovirus during natural colds.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2005;16(3):276-8.
2005: James E Gern; Louis A Rosenthal; Ronald L Sorkness; Robert F Lemanske
Effects of viral respiratory infections on lung development and childhood asthma.
The Journal of allergy and clinical immunology 2005;115(4):668-74; quiz 675.
2005: Sabine Hoffjan; Dan L Nicolae; Irina Ostrovnaya; Kathy A Roberg; Michael Evans; Daniel B Mirel; Lori Steiner; Karen Walker; Peter A Shult; Ronald E Gangnon; James E Gern; Fernando D Martinez; Robert F Lemanske; Carole Ober
Gene-environment interaction effects on the development of immune responses in the 1st year of life.
American journal of human genetics 2005;76(4):696-704.
2005: Anne G Mosser; Rose F Vrtis; Lacinda Burchell; Wai-Ming Lee; Claire R Dick; Elizabeth Weisshaar; Diane Bock; Cheri A Swenson; Richard D Cornwell; Keith C Meyer; Nizar N Jarjour; William W Busse; James E Gern
Quantitative and qualitative analysis of rhinovirus infection in bronchial tissues.
American journal of respiratory and critical care medicine 2005;171(6):645-51.
2004: Svetlana P Amineva; Aleksey G Aminev; Ann C Palmenberg; James E Gern
Rhinovirus 3C protease precursors 3CD and 3CD' localize to the nuclei of infected cells.
The Journal of general virology 2004;85(Pt 10):2969-79.
2004: Christopher C Copenhaver; James E Gern; Zhanhai Li; Peter A Shult; Louis A Rosenthal; Lance D Mikus; Carol J Kirk; Kathy A Roberg; Elizabeth L Anderson; Christopher J Tisler; Douglas F Dasilva; Heidi J Hiemke; Kevin Gentile; Ronald E Gangnon; Robert F Lemanske
Cytokine response patterns, exposure to viruses, and respiratory infections in the first year of life.
American journal of respiratory and critical care medicine 2004;170(2):175-80.
2004: Sabine Hoffjan; Irina Ostrovnaja; Dan L Nicolae; Dina L Newman; Raluca Nicolae; Ronald E Gangnon; Lori Steiner; Karen Walker; Rebecca Reynolds; Deborah Greene; Daniel Mirel; James E Gern; Robert F Lemanske; Carole Ober
Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy.
The Journal of allergy and clinical immunology 2004;113(3):511-8.
2004: James E Gern; Claudia L Reardon; Sabine Hoffjan; Dan L Nicolae; Zhanhai Li; Kathy A Roberg; William A Neaville; Kirstin T Carlson-Dakes; Kiva Adler; Rebekah Hamilton; Elizabeth Anderson; Stephanie Gilbertson-White; Christopher J Tisler; Douglas F Dasilva; Kelly Anklam; Lance D Mikus; Louis A Rosenthal; Carole Ober; Ronald E Gangnon; Robert F Lemanske
Effects of dog ownership and genotype on immune development and atopy in infancy.
The Journal of allergy and clinical immunology 2004;113(2):307-14.
2004: James E Gern
Viral respiratory infection and the link to asthma.
The Pediatric infectious disease journal 2004;23(1 Suppl):S78-86.
2003: G Daniel Brooks; Kim A Buchta; Cheri A Swenson; James E Gern; William W Busse
Rhinovirus-induced interferon-gamma and airway responsiveness in asthma.
American journal of respiratory and critical care medicine 2003;168(9):1091-4.
2003: William A Neaville; Christopher J Tisler; Abhik Bhattacharya; Kelly Anklam; Stephanie Gilbertson-White; Rebekah Hamilton; Kiva Adler; Douglas F Dasilva; Kathy A Roberg; Kirstin T Carlson-Dakes; Elizabeth Anderson; Debbie Yoshihara; Ronald E Gangnon; Lance D Mikus; Louis A Rosenthal; James E Gern; Robert F Lemanske
Developmental cytokine response profiles and the clinical and immunologic expression of atopy during the first year of life.
The Journal of allergy and clinical immunology 2003;112(4):740-6.
2003: James E Gern; Rebecca A Brockman-Schneider; Saswati Bhattacharya; James S Malter; William W Busse
Serum and low-density lipoprotein enhance interleukin-8 secretion by airway epithelial cells.
American journal of respiratory cell and molecular biology 2003;29(4):483-9.
2003: James E Gern; Robert F Lemanske
Infectious triggers of pediatric asthma.
Pediatric clinics of North America 2003;50(3):555-75, vi.
2003: James E Gern; Delores A French; Kristine A Grindle; Rebecca A Brockman-Schneider; Shinichi Konno; William W Busse
Double-stranded RNA induces the synthesis of specific chemokines by bronchial epithelial cells.
American journal of respiratory cell and molecular biology 2003;28(6):731-7.
2003: Julie M Kessel; James E Gern; Rose F Vrtis; Julie B Sedgwick; William W Busse
Ligation of intercellular adhesion molecule 3 inhibits GM-CSF production by human eosinophils.
The Journal of allergy and clinical immunology 2003;111(5):1024-31.
2003: Elinor Simons; William M Nauseef; Anh Dai Nguyen; James E Gern
The marble test for gastric outlet obstruction in chronic granulomatous disease.
The Journal of allergy and clinical immunology 2003;111(4):899-901.
2003: Anh Dai K Nguyen; James E Gern
Food allergy masquerading as foreign body obstruction.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2003;90(2):271-2.
2003: James E Gern
Mechanisms of virus-induced asthma.
The Journal of pediatrics 2003;142(2 Suppl):S9-13; discussion S13-4.
2002: James E Gern; Matthew S Martin; Kelly Anklam; Kunling Shen; Kathy A Roberg; Kirstin T Carlson-Dakes; Kiva Adler; Stephanie Gilbertson-White; Rebekah Hamilton; Peter A Shult; Carol J Kirk; Douglas F Da Silva; Sarah A Sund; Michael R Kosorok; Robert F Lemanske
Relationships among specific viral pathogens, virus-induced interleukin-8, and respiratory symptoms in infancy.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2002;13(6):386-93.
2002: Lin Ying Liu; Julie B Sedgwick; Mary Ellen Bates; Rose F Vrtis; James E Gern; Hirohita Kita; Nizar N Jarjour; William W Busse; Elizabeth A B Kelly
Decreased expression of membrane IL-5 receptor alpha on human eosinophils: II. IL-5 down-modulates its receptor via a proteinase-mediated process.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(11):6459-66.
2002: Lin Ying Liu; Julie B Sedgwick; Mary Ellen Bates; Rose F Vrtis; James E Gern; Hirohita Kita; Nizar N Jarjour; William W Busse; Elizabeth A B Kelly
Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challenge.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(11):6452-8.
2002: Julie B Sedgwick; Indu Menon; James E Gern; William W Busse
Effects of inflammatory cytokines on the permeability of human lung microvascular endothelial cell monolayers and differential eosinophil transmigration.
The Journal of allergy and clinical immunology 2002;110(5):752-6.
2002: Ronald L Sorkness; James E Gern; Kristine A Grindle; Anne G Mosser; Louis A Rosenthal; Lance D Mikus; Robert F Lemanske
Persistence of viral RNA in 2 rat strains differing in susceptibility to postbronchiolitis airway dysfunction.
The Journal of allergy and clinical immunology 2002;110(4):607-9.
2002: Shinichi Konno; Kristine A Grindle; Wai-Ming Lee; Mary K Schroth; Anne G Mosser; Rebecca A Brockman-Schneider; William W Busse; James E Gern
Interferon-gamma enhances rhinovirus-induced RANTES secretion by airway epithelial cells.
American journal of respiratory cell and molecular biology 2002;26(5):594-601.
2002: James E Gern
Rhinovirus respiratory infections and asthma.
The American journal of medicine 2002;112 Suppl 6A():19S-27S.
2002: Anne G Mosser; Rebecca A Brockman-Schneider; Svetlana P Amineva; Lacinda Burchell; Julie B Sedgwick; William W Busse; James E Gern
Similar frequency of rhinovirus-infectible cells in upper and lower airway epithelium.
The Journal of infectious diseases 2002;185(6):734-43.
2002: James E Gern; William W Busse
Relationship of viral infections to wheezing illnesses and asthma.
Nature reviews. Immunology 2002;2(2):132-8.
2002: Kishore Narayanan; Bradly J Seufzer; Rebecca A Brockman-Schneider; James E Gern; Arun Balakrishnan; shigeki miyamoto
CD14-dependent activation of NF-kappaB by filarial parasitic sheath proteins.
Cell biology international 2002;26(1):43-54.
2000: James E Gern; Rose F Vrtis; Kristine A Grindle; Cheri A Swenson; William W Busse
Relationship of upper and lower airway cytokines to outcome of experimental rhinovirus infection.
American journal of respiratory and critical care medicine 2000;162(6):2226-31.
2000: S S Eapen; E L Connor; James E Gern
Insulin desensitization with insulin lispro and an insulin pump in a 5-year-old child.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2000;85(5):395-7.
2000: James E Gern; William W Busse
The role of viral infections in the natural history of asthma.
The Journal of allergy and clinical immunology 2000;106(2):201-12.
2000: Amjad Tuffaha; James E Gern; Robert F Lemanske
The role of respiratory viruses in acute and chronic asthma.
Clinics in chest medicine 2000;21(2):289-300.
2000: Nizar N Jarjour; James E Gern; Elizabeth A B Kelly; Cheri A Swenson; C R Dick; William W Busse
The effect of an experimental rhinovirus 16 infection on bronchial lavage neutrophils.
The Journal of allergy and clinical immunology 2000;105(6 Pt 1):1169-77.
2000: D E Parry; William W Busse; K A Sukow; C R Dick; C Swenson; James E Gern
Rhinovirus-induced PBMC responses and outcome of experimental infection in allergic subjects.
The Journal of allergy and clinical immunology 2000;105(4):692-8.
2000: James E Gern
Viral and bacterial infections in the development and progression of asthma.
The Journal of allergy and clinical immunology 2000;105(2 Pt 2):S497-502.
1999: James E Gern; Robert F Lemanske; William W Busse
Early life origins of asthma.
The Journal of clinical investigation 1999;104(7):837-43.
1999: M K Schroth; E Grimm; P Frindt; DM Galagan; Shinichi Konno; R Love; James E Gern
Rhinovirus replication causes RANTES production in primary bronchial epithelial cells.
American journal of respiratory cell and molecular biology 1999;20(6):1220-8.
1999: James E Gern; William W Busse
Association of rhinovirus infections with asthma.
Clinical microbiology reviews 1999;12(1):9-18.
1998: KA McGill; Christine A Sorkness; C Ferguson-Page; James E Gern; Thomas C Havighurst; B Knipfer; Robert F Lemanske; William W Busse
Asthma in non-inner city Head Start children.
Pediatrics 1998;102(1 Pt 1):77-83.
1998: Z T Handzel; William W Busse; Julie B Sedgwick; Rose F Vrtis; Wai-Ming Lee; Elizabeth A B Kelly; James E Gern
Eosinophils bind rhinovirus and activate virus-specific T cells.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(3):1279-84.
1998: Ellen B Cook; Jim Stahl; Steven T Miller; James E Gern; K A Sukow; Frank M Graziano; Neal P Barney
Isolation of human conjunctival mast cells and epithelial cells: tumor necrosis factor-alpha from mast cells affects intercellular adhesion molecule 1 expression on epithelial cells.
Investigative ophthalmology & visual science 1998;39(2):336-43.
1997: William W Busse; James E Gern
Viruses in asthma.
The Journal of allergy and clinical immunology 1997;100(2):147-50.
1997: James E Gern; William J Calhoun; C Swenson; G Shen; William W Busse
Rhinovirus infection preferentially increases lower airway responsiveness in allergic subjects.
American journal of respiratory and critical care medicine 1997;155(6):1872-6.
1997: James E Gern; E C Dick; Elizabeth A B Kelly; Rose F Vrtis; B Klein
Rhinovirus-specific T cells recognize both shared and serotype-restricted viral epitopes.
The Journal of infectious diseases 1997;175(5):1108-14.
1997: James E Gern; DM Galagan; N N Jarjour; E C Dick; W W Busse
Detection of rhinovirus RNA in lower airway cells during experimentally induced infection.
American journal of respiratory and critical care medicine 1997;155(3):1159-61.
1997: William W Busse; James E Gern; E C Dick
The role of respiratory viruses in asthma.
Ciba Foundation symposium 1997;206():208-13; discussion 213-9.
1996: James E Gern; B Joseph; D M Galagan; W R Borcherding; E C Dick
Rhinovirus inhibits antigen-specific T cell proliferation through an intercellular adhesion molecule-1-dependent mechanism.
The Journal of infectious diseases 1996;174(6):1143-50.
1996: James E Gern; Rose F Vrtis; Elizabeth A B Kelly; E C Dick; William W Busse
Rhinovirus produces nonspecific activation of lymphocytes through a monocyte-dependent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1605-12.
1996: James E Gern; E C Dick; W M Lee; S Murray; K Meyer; Z T Handzel; William W Busse
Rhinovirus enters but does not replicate inside monocytes and airway macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):621-7.
1995: James E Gern; M K Schroth; Robert F Lemanske
Childhood asthma. Older children and adolescents.
Clinics in chest medicine 1995;16(4):657-70.
1995: James E Gern; William W Busse
The effects of rhinovirus infections on allergic airway responses.
American journal of respiratory and critical care medicine 1995;152(4 Pt 2):S40-5.