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Cristina Geroni
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Living Beings
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Network (preview)
15
Cozzi, Paolo
12
Mongelli, Nicola
11
Broggini, Massimo
10
D'Incalci, Maurizio
10
Giuliani, FC
10
Marchini, Sergio
8
Romagnoli, Romeo
8
Baraldi, Pier Giovanni
8
Beria, Italo
6
Capolongo, L
5
Arcamone, FM
5
Caldarelli, Marina
5
Spalluto, Giampiero
3
Moneta, Donatella
3
Sessa, Cristiana
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Geonetwork of Cristina Geroni (preview)
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All Publications
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2009: Pellizzari Tregno Francesca; Sau Andrea; Pezzola Silvia; Geroni Cristina; Lapenta Caterina; Spada Massimo; Filomeni Giuseppe; Bonanno Elena; Federici Giorgio; Caccuri Anna Maria
In vitro and in vivo efficacy of 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) on human melanoma.
European journal of cancer (Oxford, England : 1990) 2009;45(14):2606-17.
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2008: Quintieri Luigi; Fantin Marianna; Palatini Pietro; De Martin Sara; Rosato Antonio; Caruso Michele; Geroni Cristina; Floreani Maura
In vitro hepatic conversion of the anticancer agent nemorubicin to its active metabolite PNU-159682 in mice, rats and dogs: a comparison with human liver microsomes.
Biochemical pharmacology 2008;76(6):784-95.
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2007: Sessa Cristiana; Valota Olga; Geroni Cristina
Ongoing phase I and II studies of novel anthracyclines.
Cardiovascular toxicology 2007;7(2):75-9.
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2005: Pasello Michela; Hattinger Claudia Maria; Stoico Giuseppina; Manara Maria Cristina; Benini Stefania; Geroni Cristina; Mercuri Mario; Scotlandi Katia; Picci Piero; Serra Massimo
4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): a promising new candidate for chemotherapeutic treatment of osteosarcoma patients.
European journal of cancer (Oxford, England : 1990) 2005;41(14):2184-95.
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2005: Quintieri Luigi; Geroni Cristina; Fantin Marianna; Battaglia Rosangela; Rosato Antonio; Speed William; Zanovello Paola; Floreani Maura
Formation and antitumor activity of PNU-159682, a major metabolite of nemorubicin in human liver microsomes.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(4):1608-17.
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2004: Baraldi Pier Giovanni; Beria Italo; Cozzi Paolo; Geroni Cristina; Espinosa Antonio; Gallo Miguel A; Entrena Antonio; Bingham John P; Hartley John A; Romagnoli Romeo
Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies.
Bioorganic & medicinal chemistry 2004;12(14):3911-21.
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2004: Beria Italo; Baraldi Pier Giovanni; Cozzi Paolo; Caldarelli Marina; Geroni Cristina; Marchini Sergio; Mongelli Nicola; Romagnoli Romeo
Cytotoxic alpha-halogenoacrylic derivatives of distamycin A and congeners.
Journal of medicinal chemistry 2004;47(10):2611-23.
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2004: Broggini Massimo; Marchini Sergio; Fontana Erminia; Moneta Donatella; Fowst Camilla; Geroni Cristina
Brostallicin: a new concept in minor groove DNA binder development.
Anti-cancer drugs 2004;15(1):1-6.
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2003: Sabatino Maria Antonietta; Colombo Tina; Geroni Cristina; Marchini Sergio; Broggini Massimo
Enhancement of in vivo antitumor activity of classical anticancer agents by combination with the new, glutathione-interacting DNA minor groove-binder, brostallicin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(14):5402-8.
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2003: Fedier A; Fowst C; Tursi J; Geroni C; Haller U; Marchini S; Fink D
Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells.
British journal of cancer 2003;89(8):1559-65.
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2003: Pilati Pierluigi; Mocellin Simone; Rossi Carlo R; Scalerta Romano; Alaggio Rita; Giacomelli Luciano; Geroni Cristina; Nitti Donato; Lise Mario
Doxorubicin activity is enhanced by hyperthermia in a model of ex vivo vascular perfusion of human colon carcinoma.
World journal of surgery 2003;27(6):640-6.
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2003: Ferruzzi E; Franceschini R; Cazzolato G; Geroni C; Fowst C; Pastorino U; Tradati N; Tursi J; Dittadi R; Gion M
Blood glutathione as a surrogate marker of cancer tissue glutathione S-transferase activity in non-small cell lung cancer and squamous cell carcinoma of the head and neck.
European journal of cancer (Oxford, England : 1990) 2003;39(7):1019-29.
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2003: Moneta D; Geroni C; Valota O; Grossi P; de Jonge M J A; Brughera M; Colajori E; Ghielmini M; Sessa C
Predicting the maximum-tolerated dose of PNU-159548 (4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin) in humans using CFU-GM clonogenic assays and prospective validation.
European journal of cancer (Oxford, England : 1990) 2003;39(5):675-83.
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2002: Beria Italo; Caldarelli Marina; Geroni Cristina; Mongelli Nicola; Reinach Benedetta; Vignati Luisella; Cozzi Paolo
Cytotoxic alpha-bromoacrylic derivatives of low molecular weight.
Bioorganic & medicinal chemistry letters 2002;12(11):1467-71.
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2002: Geroni Cristina; Marchini Sergio; Cozzi Paolo; Galliera Emanuela; Ragg Enzio; Colombo Tina; Battaglia Rosangela; Howard Martin; D'Incalci Maurizio; Broggini Massimo
Brostallicin, a novel anticancer agent whose activity is enhanced upon binding to glutathione.
Cancer research 2002;62(8):2332-6.
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2001: Marchini S; Damia G; Broggini M; Pennella G; Ripamonti M; Marsiglio A; Geroni C
4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548), a novel anticancer agent active against tumor cell lines with different resistance mechanisms.
Cancer research 2001;61(5):1991-5.
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2001: Geroni C; Ripamonti M; Arrigoni C; Fiorentini F; Capolongo L; Moneta D; Marchini S; Della Torre P; Albanese C; Lamparelli M G; Ciomei M; Rossi R; Caruso M
Pharmacological and toxicological aspects of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): a novel antineoplastic agent.
Cancer research 2001;61(5):1983-90.
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2000: Cozzi P; Beria I; Caldarelli M; Capolongo L; Geroni C; Mazzini S; Ragg E
Phenyl sulfur mustard derivatives of distamycin A.
Bioorganic & medicinal chemistry letters 2000;10(15):1653-6.
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2000: Baraldi P G; Romagnoli R; Beria I; Cozzi P; Geroni C; Mongelli N; Bianchi N; Mischiati C; Gambari R
Synthesis and antitumor activity of new benzoheterocyclic derivatives of distamycin A.
Journal of medicinal chemistry 2000;43(14):2675-84.
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2000: Cozzi P; Beria I; Caldarelli M; Geroni C; Mongelli N; Pennella G
Cytotoxic alpha-bromoacrylic derivatives of distamycin analogues modified at the amidino moiety.
Bioorganic & medicinal chemistry letters 2000;10(11):1273-6.
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2000: Cozzi P; Beria I; Caldarelli M; Capolongo L; Geroni C; Mongelli N
Cytotoxic halogenoacrylic derivatives of distamycin A.
Bioorganic & medicinal chemistry letters 2000;10(11):1269-72.
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2000: Quintieri L; Rosato A; Napoli E; Sola F; Geroni C; Floreani M; Zanovello P
In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
Cancer research 2000;60(12):3232-8.
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1999: Marchini S; Cirò M; Gallinari F; Geroni C; Cozzi P; D'Incalci M; Broggini M
Alpha-bromoacryloyl derivative of distamycin A (PNU 151807): a new non-covalent minor groove DNA binder with antineoplastic activity.
British journal of cancer 1999;80(7):991-7.
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1999: Baraldi P G; Balboni G; Romagnoli R; Spalluto G; Cozzi P; Geroni C; Mongelli N; Rutigliano C; Bianchi N; Gambari R
PNU 157977: a new potent antitumour agent exhibiting low in vivo toxicity in mice injected with L1210 leukaemia cells.
Anti-cancer drug design 1999;14(1):71-6.
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1999: Baraldi P G; Cozzi P; Geroni C; Mongelli N; Romagnoli R; Spalluto G
Novel benzoyl nitrogen mustard derivatives of pyrazole analogues of distamycin A: synthesis and antileukemic activity.
Bioorganic & medicinal chemistry 1999;7(2):251-62.
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1998: Marchini S; Cozzi P; Beria I; Geroni C; Capolongo L; D'Incalci M; Broggini M
Sequence-specific DNA alkylation of novel tallimustine derivatives.
Anti-cancer drug design 1998;13(3):193-205.
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1998: Ghielmini M; Colli E; Bosshard G; Pennella G; Geroni C; Torri V; D'Incalci M; Cavalli F; Sessa C
Hematotoxicity on human bone marrow- and umbilical cord blood-derived progenitor cells and in vitro therapeutic index of methoxymorpholinyldoxorubicin and its metabolites.
Cancer chemotherapy and pharmacology 1998;42(3):235-40.
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1997: Baraldi P G; Cacciari B; Guiotto A; Romagnoli R; Spalluto G; Zaid A N; Capolongo L; Cozzi P; Geroni C; Mongelli N
Synthesis, solvolytic stability and cytotoxicity of a modified derivative of CPzI, a pyrazole analog of the alkylation subunit of the antitumor agent CC-1065: effect of the nitrogen substitution on the functional reactivity.
Farmaco (Società chimica italiana : 1989) 1997;52(12):717-23.
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1997: Baraldi P G; Cacciari B; Guiotto A; Romagnoli R; Spalluto G; Zaid A N; Cozzi P; Geroni C; Mongelli N
Synthesis, cytotoxicity and antitumor activity of some new simplified pyrazole analogs of the antitumor agent CC-1065. Effect of an hydrophobic group on antitumor activity.
Farmaco (Società chimica italiana : 1989) 1997;52(12):711-6.
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1997: Baraldi P G; Cacciari B; Romagnoli R; Spalluto G; Gambari R; Bianchi N; Passadore M; Ambrosino P; Mongelli N; Cozzi P; Geroni C
Synthesis, cytotoxicity, antitumor activity and sequence selective binding of two pyrazole analogs structurally related to the antitumor agents U-71,184 and adozelesin.
Anti-cancer drug design 1997;12(7):555-76.
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1995: Marchini S; Gonzalez Paz O; Ripamonti M; Geroni C; Bargiotti A; Caruso M; Todeschi S; D'Incalci M; Broggini M
Sequence-specific DNA interactions by novel alkylating anthracycline derivatives.
Anti-cancer drug design 1995;10(8):641-53.
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1995: Ciomei M; Pastori W; Capolongo L; Geroni C; Melegaro G; Pennella G; Grandi M
Decreased tyrosine phosphorylation in tumour cells resistant to FCE 24517 (tallimustine).
British journal of cancer 1995;72(6):1504-8.
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1994: Geroni C; Pesenti E; Broggini M; Belvedere G; Tagliabue G; D'Incalci M; Pennella G; Grandi M
L1210 cells selected for resistance to methoxymorpholinyl doxorubicin appear specifically resistant to this class of morpholinyl derivatives.
British journal of cancer 1994;69(2):315-9.
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1993: Tagliabue G; Pifferi A; Balconi G; Mascellani E; Geroni C; D'Incalci M; Ubezio P
Intracellular glutathione heterogeneity in L1210 murine leukemia sublines made resistant to DNA-interacting anti-neoplastic agents.
International journal of cancer. Journal international du cancer 1993;54(3):435-42.
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1993: Geroni C; Pesenti E; Tagliabue G; Ballinari D; Mongelli N; Broggini M; Erba E; D'Incalci M; Spreafico F; Grandi M
Establishment of L1210 leukemia cells resistant to the distamycin-A derivative (FCE 24517): characterization and cross-resistance studies.
International journal of cancer. Journal international du cancer 1993;53(2):308-14.
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1991: Facchetti I; Grandi M; Cucchi P; Geroni C; Penco S; Vigevani A
Influence of lipophilicity on cytotoxicity of anthracyclines in LoVo and LoVo/Dx human cell lines.
Anti-cancer drug design 1991;6(5):385-97.
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1991: Broggini M; Erba E; Ponti M; Ballinari D; Geroni C; Spreafico F; D'Incalci M
Selective DNA interaction of the novel distamycin derivative FCE 24517.
Cancer research 1991;51(1):199-204.
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1990: Cassinelli G; Arlandini E; Ballabio M; Bordoni T; Geroni C; Giuliani F; Grein A; Merli S; Rivola G
New biosynthetic anthracyclines related to barminomycins incorporating barbiturates in their moiety.
The Journal of antibiotics 1990;43(1):19-28.
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1990: Cantoni O; Sestili P; Cattabeni F; Geroni C; Giuliani F
Comparative effects of doxorubicin and 4'-epi-doxorubicin on nucleic acid metabolism and cytotoxicity in a human tumor cell line.
Cancer chemotherapy and pharmacology 1990;27(1):47-51.
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1989: Belvedere G; Suarato A; Geroni C; Giuliani F C; D'Incalci M
Comparison of intracellular drug retention, DNA damage and cytotoxicity of derivatives of doxorubicin and daunorubicin in a human colon adenocarcinoma cell line (LoVo).
Biochemical pharmacology 1989;38(21):3713-21.
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1989: Arcamone F M; Animati F; Barbieri B; Configliacchi E; D'Alessio R; Geroni C; Giuliani F C; Lazzari E; Menozzi M; Mongelli N
Synthesis, DNA-binding properties, and antitumor activity of novel distamycin derivatives.
Journal of medicinal chemistry 1989;32(4):774-8.
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1989: Cantoni O; Sestili P; Cattabeni F; Geroni C; Grandi M; Giuliani F C
Cellular and molecular pharmacology of 4'-epidoxorubicin in HeLa cells. Comparison with its parent drug, doxorubicin.
Journal of cancer research and clinical oncology 1989;115(4):373-8.
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1988: Broggini M; Grandi M; Ubezio P; Geroni C; Giuliani F C; D'Incalci M
Intracellular doxorubicin concentrations and drug-induced DNA damage in a human colon adenocarcinoma cell line and in a drug-resistant subline.
Biochemical pharmacology 1988;37(23):4423-31.
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1988: Rizzo V; Penco S; Menozzi M; Geroni C; Vigevani A; Arcamone F
Studies of anthracycline--DNA complexes by circular dichroism.
Anti-cancer drug design 1988;3(2):103-15.
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1988: Cristalli G; Franchetti P; Grifantini M; Vittori S; Lupidi G; Riva F; Bordoni T; Geroni C; Verini M A
Adenosine deaminase inhibitors. Synthesis and biological activity of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine.
Journal of medicinal chemistry 1988;31(2):390-3.
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1987: Cristalli G; Franchetti P; Grifantini M; Vittori S; Bordoni T; Geroni C
Improved synthesis and antitumor activity of 1-deazaadenosine.
Journal of medicinal chemistry 1987;30(9):1686-8.
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1987: Barbieri B; Giuliani F C; Bordoni T; Casazza A M; Geroni C; Bellini O; Suarato A; Gioia B; Penco S; Arcamone F
Chemical and biological characterization of 4'-iodo-4'-deoxydoxorubicin.
Cancer research 1987;47(15):4001-6.
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1986: Cassinelli G; Geroni C; Botta B; delle Monache G; delle Monache F
Cytotoxic and antitumor activity of vismiones isolated from vismieae.
Journal of natural products 1986;49(5):929-31.
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1986: Grandi M; Geroni C; Giuliani F C
Isolation and characterization of a human colon adenocarcinoma cell line resistant to doxorubicin.
British journal of cancer 1986;54(3):515-8.
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1986: Spadari S; Pedrali-Noy G; Focher F; Montecucco A; Bordoni T; Geroni C; Giuliani F C; Ventrella G; Arcamone F; Ciarrocchi G
DNA polymerases and DNA topoisomerases as targets for the development of anticancer drugs.
Anticancer research 1986;6(5):935-40.
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1986: Zunino F; Barbieri B; Bellini O; Casazza A M; Geroni C; Giuliani F; Ciana A; Manzini G; Quadrifoglio F
Biochemical and biological activity of the anthracycline analog, 4-demethyl-6-O-methyl-doxorubicin.
Investigational new drugs 1986;4(1):17-23.
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1986: Facchinetti T; Geroni C; Fumagalli A; Giuliani F C
In vitro studies on anthracycline haloderivatives.
Drugs under experimental and clinical research 1986;12(8):657-61.
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1983: Penco S; Casazza A M; Franchi G; Barbieri B; Bellini O; Podestà A; Savi G; Pratesi G; Geroni C; Di Marco A; Arcamone F
Synthesis, antitumor activity, and cardiac toxicity of new 4-demethoxyanthracyclines.
Cancer treatment reports 1983;67(7-8):665-73.
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1981: Zunino F; Gambetta R; Vigevani A; Penco S; Geroni C; Di Marco A
Biologic activity of daunorubicin linked to proteins via the methylketone side chain.
Tumori 1981;67(6):521-4.
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