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Stanton Gerson

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Michael S Gordon; Bryan R Leigh; Lili Liu; David Mendelson; Ramesh K Ramanathan; Lee S Rosen; Shawn Spencer; Charles P Theuer; Bonne J Adams; Stephen P Anthony; William D Figg; Stanton L Gerson; Jonathan Goldman; Yan Xu; Glen J Weiss
A phase 1 study of TRC102, an inhibitor of base excision repair, and pemetrexed in patients with advanced solid tumors.
Wen-Mei Yu; Jinhua Shen; Hal E Broxmeyer; TOREN FINKEL; Stanton L Gerson; Olga Jovanovic; Xia Liu; Elena E Pohl; Cheng-Kui Qu
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation.
Guangjin Zhou; G Brandon Atkins; Brett R Blackman; Lauren Boerboom; Amar Desai; Ryan E Feaver; Huiyun Gao; Stanton L Gerson; Andrew Hale; Anne Hamik; Xudong Liao; Yuan Lu; Lalitha Nayak; Alvin Schmaier; Nikunj Sharma; Hong Shi; Daniel I Simon; Hongmei Tian; Yunmei Wang; Mukesh K Jain
Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice.

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All Publications

2013: Michael S Gordon; Bryan R Leigh; Lili Liu; David Mendelson; Ramesh K Ramanathan; Lee S Rosen; Shawn Spencer; Charles P Theuer; Bonne J Adams; Stephen P Anthony; William D Figg; Stanton L Gerson; Jonathan Goldman; Yan Xu; Glen J Weiss
A phase 1 study of TRC102, an inhibitor of base excision repair, and pemetrexed in patients with advanced solid tumors.
Investigational new drugs 2013;31(3):714-23.
2013: Wen-Mei Yu; Jinhua Shen; Hal E Broxmeyer; TOREN FINKEL; Stanton L Gerson; Olga Jovanovic; Xia Liu; Elena E Pohl; Cheng-Kui Qu
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation.
Cell stem cell 2013;12(1):62-74.
2012: Guangjin Zhou; G Brandon Atkins; Brett R Blackman; Lauren Boerboom; Amar Desai; Ryan E Feaver; Huiyun Gao; Stanton L Gerson; Andrew Hale; Anne Hamik; Xudong Liao; Yuan Lu; Lalitha Nayak; Alvin Schmaier; Nikunj Sharma; Hong Shi; Daniel I Simon; Hongmei Tian; Yunmei Wang; Mukesh K Jain
Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice.
The Journal of clinical investigation 2012;122(12):4727-31.
2012: Allison G Condie; Stanton L Gerson; Robert H Miller; Yanming Wang
Two-photon fluorescent imaging of myelination in the spinal cord.
ChemMedChem 2012;7(12):2194-203.
2012: Rustom Falahati; Linda Flebbe-Rehwaldt; Stanton L Gerson; Yimin Shi; Jianqing Zhang; Karin M L Gaensler
Chemoselection of allogeneic HSC after murine neonatal transplantation without myeloablation or post-transplant immunosuppression.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(11):2180-9.
2012: Jonathan Kenyon; Karen Lingas; Gabriela Santos Guasch; Anshul Saurastri; Emily Thomas; David Wald; Pingfu Fu; Stanton L Gerson
Humans accumulate microsatellite instability with acquired loss of MLH1 protein in hematopoietic stem and progenitor cells as a function of age.
Blood 2012;120(16):3229-36.
2012: Shuming Yang; Stanton L Gerson; Lili Liu; Panayiotis Savvides; Yan Xu
Development and validation of an LC-MS/MS method for pharmacokinetic study of methoxyamine in phase I clinical trial.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;901():25-33.
2012: Narin Apisarnthanarax; Sean Carlson; Derek V Chan; Pingfu Fu; Stanton L Gerson; Anita Gilliam; Lili Liu; Scot C Remick; Seth R Stevens; Sarolta K Szabo; Gary S Wood; Kevin D Cooper
Phase I clinical trial of O6-benzylguanine and topical carmustine in the treatment of cutaneous T-cell lymphoma, mycosis fungoides type.
Archives of dermatology 2012;148(5):613-20.
2012: Yulan Qing; Yuan Lin; Stanton L Gerson
An intrinsic BM hematopoietic niche occupancy defect of HSC in scid mice facilitates exogenous HSC engraftment.
Blood 2012;119(7):1768-71.
2012: Justin Roth; Giuliana Ferrari; Mourad Ismail; Karen T Lingas; Jane S Reese; Stanton L Gerson
Cotransduction with MGMT and Ubiquitous or Erythroid-Specific GFP Lentiviruses Allows Enrichment of Dual-Positive Hematopoietic Progenitor Cells In Vivo.
ISRN hematology 2012;2012():212586.
2012: Michael O Alberti; Edward Abraham; Stanton L Gerson; Mourad Ismail; Larisa Pereboeva; Justin Roth; Yuko Tsuruta; David T Curiel
Derivation of a myeloid cell-binding adenovirus for gene therapy of inflammation.
PloS one 2012;7(5):e37812.
2011: Dan Xu; Wen-Mei Yu; Stanton L Gerson; Caiying Guo; Xia Liu; Howard J Meyerson; Cheng-Kui Qu
Non-lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells.
The Journal of experimental medicine 2011;208(10):1977-88.
2011: Hillard M Lazarus; F Liu; Scott R Sommers; N M Kaye; Tamila L Kindwall-Keller; Mary J Laughlin; Lisa M Arfons; S A Ataergin; Paul M Barr; Brenda W Cooper; Richard J Creger; Pingfu Fu; Stanton L Gerson; David Kaplan
Spontaneous autologous graft-versus-host disease in plasma cell myeloma autograft recipients: flow cytometric analysis of hematopoietic progenitor cell grafts.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2011;17(7):970-8.
2011: Yuan Lin; Justin Roth; David L Wilson; Perrin Cheung; Stanton L Gerson
Imaging stem cell-derived persistent foci after in vivo selection of lentiviral MGMT-P140K transduced murine bone marrow cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(7):1342-52.
2011: Maria C Athanasiou; Michael Dettling; Ingolf Cascorbi; Igor Mosyagin; Benjamin A Salisbury; Kerri A Pierz; Wei Zou; Heidi Whalen; Anil Malhotra; Todd Lencz; Stanton L Gerson; John M Kane; Carol R Reed
Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine-induced agranulocytosis.
The Journal of clinical psychiatry 2011;72(4):458-63.
2010: David A Rizzieri; Samantha LoRusso; William Tse; Khuda Khan; Anjali Advani; Joseph Moore; Verena Karsten; Ann Cahill; Stanton L Gerson
Phase I study of temozolomide and laromustine (VNP40101M) in patients with relapsed or refractory leukemia.
Clinical lymphoma, myeloma & leukemia 2010;10(3):211-6.
2009: Yanming Wang; Lili Liu; Chunying Wu; Alina Bulgar; Eduardo Somoza; Wenxia Zhu; Stanton L Gerson
Direct detection and quantification of abasic sites for in vivo studies of DNA damage and repair.
Nuclear medicine and biology 2009;36(8):975-83.
2009: Paul M Barr; Pingfu Fu; Hillard M Lazarus; Nancy Horvath; Stanton L Gerson; Omer N Koc; Nizar J Bahlis; Michael R Snell; Afshin Dowlati; Brenda W Cooper
Phase I trial of fludarabine, bortezomib and rituximab for relapsed and refractory indolent and mantle cell non-Hodgkin lymphoma.
British journal of haematology 2009;147(1):89-96.
2009: Crawford J Strunk; Uwe Platzbecker; Christian Thiede; Markus Schaich; Thomas Illmer; Zizhen Kang; Patrick Leahy; Chunbiao Li; Xiuyan Xie; Mary J Laughlin; Hillard M Lazarus; Stanton L Gerson; Kevin D Bunting; Gerhard Ehninger; William Tse
Elevated AF1q expression is a poor prognostic marker for adult acute myeloid leukemia patients with normal cytogenetics.
American journal of hematology 2009;84(5):308-9.
2009: Fangjing Wang; James E Dennis; Amad Awadallah; Luis A Solchaga; Joseph Molter; Yu Kuang; Nicolas Salem; Yuan Lin; Haibin Tian; Jeffery A Kolthammer; Yunhui Kim; Zachary B Love; Stanton L Gerson; Zhenghong Lee
Transcriptional profiling of human mesenchymal stem cells transduced with reporter genes for imaging.
Physiological genomics 2009;37(1):23-34.
2008: Z Tang; R Du; S Jiang; Chuanyue Wu; D S Barkauskas; J Richey; J Molter; M Lam; Chris A Flask; Stanton L Gerson; Afshin Dowlati; L Liu; Zhenghong Lee; Balazs Halmos; Y Wang; Jeffrey A Kern; Patrick C Ma
Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer.
British journal of cancer 2008;99(6):911-22.
2008: Zhenghong Lee; James E Dennis; Stanton L Gerson
Imaging stem cell implant for cellular-based therapies.
Experimental biology and medicine (Maywood, N.J.) 2008;233(8):930-40.
2008: David N Wald; Hanna M Vermaat; Shaolei Zang; Andrew Lavik; Zizhen Kang; Gil Peleg; Stanton L Gerson; Kevin D Bunting; Munna L Agarwal; Bryan L Roth; William Tse
Identification of 6-benzylthioinosine as a myeloid leukemia differentiation-inducing compound.
Cancer research 2008;68(11):4369-76.
2008: Yong Gao; Michael A Lobritz; Justin Roth; Measho Abreha; Kenneth N Nelson; Immaculate Nankya; Dawn M Moore-Dudley; Awet Abraha; Stanton L Gerson; Eric J Arts
Targets of small interfering RNA restriction during human immunodeficiency virus type 1 replication.
Journal of virology 2008;82(6):2938-51.
2008: Jane S Reese; Justin Roth; Stanton L Gerson
Bone marrow-derived cells exhibiting lung epithelial cell characteristics are enriched in vivo using methylguanine DNA methyltransferase-mediated drug resistance.
Stem cells (Dayton, Ohio) 2008;26(3):675-81.
2008: Pingfu Fu; Willem J van Heeckeren; Punit D Wadhwa; D J Bajor; Richard J Creger; Z Xu; Brenda W Cooper; Mary J Laughlin; Stanton L Gerson; Omer N Koç; Hillard M Lazarus
Time-dependent effect of non-Hodgkin's lymphoma grade on disease-free survival of relapsed/refractory patients treated with high-dose chemotherapy plus autotransplantation.
Contemporary clinical trials 2008;29(2):157-64.
2008: Sridharan Gururangan; Christopher D Turner; Clinton F Stewart; Melinda O'Shaughnessy; Mehmet Kocak; Tina Young Poussaint; Peter C Phillips; Stewart Goldman; Roger Packer; Ian F Pollack; Susan M Blaney; Verena Karsten; Stanton L Gerson; James M Boyett; Henry S Friedman; Larry E Kun
Phase I trial of VNP40101M (Cloretazine) in children with recurrent brain tumors: a pediatric brain tumor consortium study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):1124-30.
2008: Yuan Lin; Joe Molter; Zhenghong Lee; Stanton L Gerson
Bioluminescence imaging of hematopoietic stem cell repopulation in murine models.
Methods in molecular biology (Clifton, N.J.) 2008;430():295-306.
2007: Eric D Batts; Christopher Maisel; Donna Kane; Lili Liu; Pingfu Fu; Timothy O'Brien; Scot C Remick; Nizar J Bahlis; Stanton L Gerson
O6-benzylguanine and BCNU in multiple myeloma: a phase II trial.
Cancer chemotherapy and pharmacology 2007;60(3):415-21.
2007: Ling Yan; Alina Bulgar; Yanling Miao; Varun Mahajan; Jon R Donze; Stanton L Gerson; Lili Liu
Combined treatment with temozolomide and methoxyamine: blocking apurininc/pyrimidinic site repair coupled with targeting topoisomerase IIalpha.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(5):1532-9.
2007: Jonathan Kenyon; Stanton L Gerson
The role of DNA damage repair in aging of adult stem cells.
Nucleic acids research 2007;35(22):7557-65.
2006: Pingfu Fu; R K Bagai; Howard J Meyerson; D Kane; Robert M Fox; Richard J Creger; Brenda W Cooper; Stanton L Gerson; Mary J Laughlin; Omer N Koc; Hillard M Lazarus
Pre-mobilization therapy blood CD34+ cell count predicts the likelihood of successful hematopoietic stem cell mobilization.
Bone marrow transplantation 2006;38(3):189-96.
2006: Meltem Yüksel; Elma D Baron; Melissa Camouse; Brenda W Cooper; Hillard M Lazarus; Stanton L Gerson; Mary J Laughlin; Kevin D Cooper; Anita Gilliam; Pingfu Fu; Seth Stevens; Omer N Koç
Peritransplant use of ultraviolet-B irradiation (UV-B) therapy is detrimental to allogeneic stem cell transplantation outcome.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(6):665-71.
2006: Feng-Qi An; Hope Merlene Folarin; Nicole Compitello; Justin Roth; Stanton L Gerson; Keith R McCrae; Farnaz D Fakhari; Dirk P Dittmer; Rolf Renne
Long-term-infected telomerase-immortalized endothelial cells: a model for Kaposi's sarcoma-associated herpesvirus latency in vitro and in vivo.
Journal of virology 2006;80(10):4833-46.
2006: Stanton L Gerson
Clozapine alone versus clozapine and risperidone for refractory schizophrenia.
The New England journal of medicine 2006;354(17):1846-8; author reply 1846-8.
2006: Lili Liu; Stanton L Gerson
Targeted modulation of MGMT: clinical implications.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(2):328-31.
2006: Aparecida Maria Fontes; Brian M Davis; Lance P Encell; Karen T Lingas; Dimas Tadeu Covas; Marco Zago; Lawrence A Loeb; Anthony E Pegg; Stanton L Gerson
Differential competitive resistance to methylating versus chloroethylating agents among five O6-alkylguanine DNA alkyltransferases in human hematopoietic cells.
Molecular cancer therapeutics 2006;5(1):121-8.
2006: Willem J van Heeckeren; Jennifer Vollweiler; Pingfu Fu; Brenda W Cooper; Howard J Meyerson; Hillard M Lazarus; Alexandra Simic; Mary J Laughlin; Stanton L Gerson; Omer N Koç
Randomised comparison of two B-cell purging protocols for patients with B-cell non-Hodgkin lymphoma: in vivo purging with rituximab versus ex vivo purging with CliniMACS CD34 cell enrichment device.
British journal of haematology 2006;132(1):42-55.
2005: Thomas F Gajewski; Jeffrey A Sosman; Stanton L Gerson; Lili Liu; Eileen Dolan; Shang Lin; Everett E Vokes
Phase II trial of the O6-alkylguanine DNA alkyltransferase inhibitor O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea in advanced melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7861-5.
2005: Nizar J Bahlis; Yanling Miao; Omer N Koc; Kelvin Lee; Lawrence Boise; Stanton L Gerson
N-benzoylstaurosporine (PKC412) inhibits Akt kinase inducing apoptosis in multiple myeloma cells.
Leukemia & lymphoma 2005;46(6):899-908.
2005: Hillard M Lazarus; Omer N Koc; Steven M Devine; Peter Curtin; Richard T Maziarz; H Kent Holland; Elizabeth J Shpall; Philip McCarthy; Kerry Atkinson; Brenda W Cooper; Stanton L Gerson; Mary J Laughlin; Fausto R Loberiza; Annemarie Moseley; Andrea Bacigalupo
Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(5):389-98.
2005: Youngji Park; Stanton L Gerson
DNA repair defects in stem cell function and aging.
Annual review of medicine 2005;56():495-508.
2005: Punit D Wadhwa; Pingfu Fu; Omer N Koc; Brenda W Cooper; Robert M Fox; Richard J Creger; David L Bajor; Teja Bedi; Mary J Laughlin; Jennifer Payne; Stanton L Gerson; Hillard M Lazarus
High-dose carmustine, etoposide, and cisplatin for autologous stem cell transplantation with or without involved-field radiation for relapsed/refractory lymphoma: an effective regimen with low morbidity and mortality.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(1):13-22.
2004: Emmanuel Richard; Elodie Robert; Muriel Cario-André; Cécile Ged; Fabien Géronimi; Stanton L Gerson; Hubert de Verneuil; François Moreau-Gaudry
Hematopoietic stem cell gene therapy of murine protoporphyria by methylguanine-DNA-methyltransferase-mediated in vivo drug selection.
Gene therapy 2004;11(22):1638-47.
2004: Brenda W Cooper; Gareth Veal; Tomas Radivoyevitch; Michael J Tilby; Howard J Meyerson; Hillard M Lazarus; Omer N Koc; Richard J Creger; Graham Pearson; Geoff M Nowell; David Gosky; Stephen T Ingalls; Charles L Hoppel; Stanton L Gerson
A phase I and pharmacodynamic study of fludarabine, carboplatin, and topotecan in patients with relapsed, refractory, or high-risk acute leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(20):6830-9.
2004: Lili Liu; Stanton L Gerson
Therapeutic impact of methoxyamine: blocking repair of abasic sites in the base excision repair pathway.
Current opinion in investigational drugs (London, England : 2000) 2004;5(6):623-7.
2004: Steven P Zielske; Karen T Lingas; Yan Li; Stanton L Gerson
Limited lentiviral transgene expression with increasing copy number in an MGMT selection model: lack of copy number selection by drug treatment.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;9(6):923-31.
2004: Stanton L Gerson
MGMT: its role in cancer aetiology and cancer therapeutics.
Nature reviews. Cancer 2004;4(4):296-307.
2004: Lisa A Hammond; John R Eckardt; John Kuhn; Stanton L Gerson; Tom Johnson; Lon Smith; Ronald L Drengler; Elizabeth Campbell; Geoffrey R Weiss; Daniel Von Hoff; Eric K Rowinsky
A randomized phase I and pharmacological trial of sequences of 1,3-bis(2-chloroethyl)-1-nitrosourea and temozolomide in patients with advanced solid neoplasms.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(5):1645-56.
2003: Afshin Dowlati; Hillard M Lazarus; Paul Hartman; James Jacobberger; Cecilia M Whitacre; Stanton L Gerson; Pamela Ksenich; Brenda W Cooper; Phyllis S Frisa; Megan Gottlieb; Anthony J Murgo; Scot C Remick
Phase I and correlative study of combination bryostatin 1 and vincristine in relapsed B-cell malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(16 Pt 1):5929-35.
2003: Steven P Zielske; Jane S Reese; Karen T Lingas; Jon R Donze; Stanton L Gerson
In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning.
The Journal of clinical investigation 2003;112(10):1561-70.
2003: Shuming Yang; Lili Liu; Stanton L Gerson; Yan Xu
Measurement of anti-cancer agent methoxyamine in plasma by tandem mass spectrometry with on-line sample extraction.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;795(2):295-307.
2003: Lili Liu; Ling Yan; Jon R Donze; Stanton L Gerson
Blockage of abasic site repair enhances antitumor efficacy of 1,3-bis-(2-chloroethyl)-1-nitrosourea in colon tumor xenografts.
Molecular cancer therapeutics 2003;2(10):1061-6.
2003: Emmanuel Richard; Fabien Géronimi; Magalie Lalanne; Cécile Ged; Isabelle Redonnet-Vernhet; Isabelle Lamrissi-Garcia; Stanton L Gerson; Hubert de Verneuil; François Moreau-Gaudry
A bicistronic SIN-lentiviral vector containing G156A MGMT allows selection and metabolic correction of hematopoietic protoporphyric cell lines.
The journal of gene medicine 2003;5(9):737-47.
2003: Omer N Koç; Stanton L Gerson
Akt helps stem cells heal the heart.
Nature medicine 2003;9(9):1109-10.
2003: Jane S Reese; Lili Liu; Stanton L Gerson
Repopulating defect of mismatch repair-deficient hematopoietic stem cells.
Blood 2003;102(5):1626-33.
2003: Brian M Davis; Jane S Reese; Karen T Lingas; Stanton L Gerson
Drug selection of mutant methylguanine methyltransferase from different oncoretroviral backbones results in multilineage hematopoietic transgene expression in primary and secondary recipients.
Journal of hematotherapy & stem cell research 2003;12(4):375-87.
2003: Kou-Yi Tserng; Stephen T Ingalls; Erik M Boczko; Timothy P Spiro; Xiaolin Li; Susan Majka; Stanton L Gerson; James Willson; Charles L Hoppel
Pharmacokinetics of O6-benzylguanine (NSC637037) and its metabolite, 8-oxo-O6-benzylguanine.
Journal of clinical pharmacology 2003;43(8):881-93.
2003: Fred O Odago; Stanton L Gerson
Telomerase inhibition and telomere erosion: a two-pronged strategy in cancer therapy.
Trends in pharmacological sciences 2003;24(7):328-31.
2003: Steven P Zielske; Stanton L Gerson
SarCNU mediates selection of P140K methylguanine-DNA-methyltransferase transduced human CD34(+) cells in vitro.
Blood cells, molecules & diseases 2003;31(1):48-50.
2003: Janice E Bowman; Jane S Reese; Karen T Lingas; Stanton L Gerson
Myeloablation is not required to select and maintain expression of the drug-resistance gene, mutant MGMT, in primary and secondary recipients.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;8(1):42-50.
2003: J L Vollweiler; Steven P Zielske; Jane S Reese; Stanton L Gerson
Hematopoietic stem cell gene therapy: progress toward therapeutic targets.
Bone marrow transplantation 2003;32(1):1-7.
2003: Steven P Zielske; Stanton L Gerson
Cytokines, including stem cell factor alone, enhance lentiviral transduction in nondividing human LTCIC and NOD/SCID repopulating cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(3):325-33.
2003: Brenda W Cooper; Erin Donaher; Hillard M Lazarus; Sylvan B Green; David Gosky; Nancy S Rosenthal; Sosamma J Berger; Xiaolin Li; Stephen T Ingalls; Charles L Hoppel; Stanton L Gerson
A phase I and pharmacodynamic study of sequential topotecan and etoposide in patients with relapsed or refractory acute myelogenous and lymphoblastic leukemia.
Leukemia research 2003;27(1):35-44.
2002: Hang Zhou; Lili Liu; Keunmyoung Lee; Xiusheng Qin; Adam W Grasso; Hsing-Jien Kung; Joseph E Willis; Jeffery Kern; Thomas E Wagner; Stanton L Gerson
Lung tumorigenesis associated with erb-B-2 and erb-B-3 overexpression in human erb-B-3 transgenic mice is enhanced by methylnitrosourea.
Oncogene 2002;21(57):8732-40.
2002: Lili Liu; Yoko Nakatsuru; Stanton L Gerson
Base excision repair as a therapeutic target in colon cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2985-91.
2002: Omer N Koç; J Day; ML Nieder; Stanton L Gerson; Hillard M Lazarus; William Krivit
Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH).
Bone marrow transplantation 2002;30(4):215-22.
2002: Stanton L Gerson; Sheldon L Kaplan; Jon Bruss; Vu Le; Felix M Arellano; Barry Hafkin; David J Kuter
Hematologic effects of linezolid: summary of clinical experience.
Antimicrobial agents and chemotherapy 2002;46(8):2723-6.
2002: Lili Liu; Stuart Schwartz; Brian M Davis; Stanton L Gerson
Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.
Cancer research 2002;62(11):3070-6.
2002: Stanton L Gerson
Clinical relevance of MGMT in the treatment of cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(9):2388-99.
2002: Steven P Zielske; Stanton L Gerson
Lentiviral transduction of P140K MGMT into human CD34(+) hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(4):381-7.
2002: Christopher B Ballas; Steven P Zielske; Stanton L Gerson
Adult bone marrow stem cells for cell and gene therapies: implications for greater use.
Journal of cellular biochemistry. Supplement 2002;38():20-8.
2002: Punit D Wadhwa; Steven P Zielske; Justin Roth; Christopher B Ballas; Janice E Bowman; Stanton L Gerson
Cancer gene therapy: scientific basis.
Annual review of medicine 2002;53():437-52.
2001: K Lee; Stanton L Gerson; Basabi Maitra; Omer N Koç
G156A MGMT-transduced human mesenchymal stem cells can be selectively enriched by O6-benzylguanine and BCNU.
Journal of hematotherapy & stem cell research 2001;10(5):691-701.
2001: Afshin Dowlati; John R Haaga; Scot C Remick; Timothy P Spiro; Stanton L Gerson; Lili Liu; Sosamma J Berger; Nathan A Berger; James Willson
Sequential tumor biopsies in early phase clinical trials of anticancer agents for pharmacodynamic evaluation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(10):2971-6.
2001: Hang Zhou; Wei-Dong Chen; Xiusheng Qin; K Lee; Lili Liu; Sanford D Markowitz; Stanton L Gerson
MMTV promoter hypomethylation is linked to spontaneous and MNU associated c-neu expression and mammary carcinogenesis in MMTV c-neu transgenic mice.
Oncogene 2001;20(42):6009-17.
2001: Jane S Reese; E Allay; Stanton L Gerson
Overexpression of human O6-alkylguanine DNA alkyltransferase (AGT) prevents MNU induced lymphomas in heterozygous p53 deficient mice.
Oncogene 2001;20(38):5258-63.
2001: Lili Liu; Timothy P Spiro; Xiusheng Qin; Susan Majka; John R Haaga; Jane E Schupp; James Willson; Stanton L Gerson
Differential degradation rates of inactivated alkyltransferase in blood mononuclear cells and tumors of patients after treatment with O(6)-benzylguanine.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2318-24.
2001: Timothy P Spiro; Lili Liu; Susan Majka; John R Haaga; James Willson; Stanton L Gerson
Temozolomide: the effect of once- and twice-a-day dosing on tumor tissue levels of the DNA repair protein O(6)-alkylguanine-DNA-alkyltransferase.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2309-17.
2001: Mary J Laughlin; Juliet N Barker; B Bambach; Omer N Koc; David A Rizzieri; John E Wagner; Stanton L Gerson; Hillard M Lazarus; Mitchell S Cairo; Cladd E Stevens; Pablo Rubinstein; Joanne Kurtzberg
Hematopoietic engraftment and survival in adult recipients of umbilical-cord blood from unrelated donors.
The New England journal of medicine 2001;344(24):1815-22.
2001: Pietro Taverna; Lili Liu; Hwa-shin Hwang; A J Hanson; Timothy J Kinsella; Stanton L Gerson
Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells.
Mutation research 2001;485(4):269-81.
2001: Brian M Davis; Lance P Encell; Steven P Zielske; FC Christians; Lili Liu; S E Friebert; Lawrence A Loeb; Stanton L Gerson
Applied molecular evolution of O6-benzylguanine-resistant DNA alkyltransferases in human hematopoietic cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):4950-4.
2001: Afshin Dowlati; C L Hoppel; Stephen T Ingalls; Susan Majka; X Li; N Sedransk; T Spiro; Stanton L Gerson; Percy Ivy; Scot C Remick
Phase I clinical and pharmacokinetic study of rebeccamycin analog NSC 655649 given daily for five consecutive days.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(8):2309-18.
2001: Jane S Reese; Xiusheng Qin; Christopher B Ballas; M Sekiguchi; Stanton L Gerson
MGMT expression in murine bone marrow is a major determinant of animal survival after alkylating agent exposure.
Journal of hematotherapy & stem cell research 2001;10(1):115-23.
2000: Manas Majumdar; MA Thiede; Stephen E Haynesworth; Scott P Bruder; Stanton L Gerson
Human marrow-derived mesenchymal stem cells (MSCs) express hematopoietic cytokines and support long-term hematopoiesis when differentiated toward stromal and osteogenic lineages.
Journal of hematotherapy & stem cell research 2000;9(6):841-8.
2000: Stanton L Gerson
Drug resistance gene transfer: Stem cell protection and therapeutic efficacy.
Experimental hematology 2000;28(12):1315-24.
2000: Rui Chen; S Nagarajan; G M Prince; U Maheshwari; L W Terstappen; D R Kaplan; Stanton L Gerson; Jeffrey M Albert; Daniel E Dunn; Hillard M Lazarus; M Edward Medof
Impaired growth and elevated fas receptor expression in PIGA(+) stem cells in primary paroxysmal nocturnal hemoglobinuria.
The Journal of clinical investigation 2000;106(5):689-96.
2000: Timothy P Spiro; Lili Liu; Stanton L Gerson
New cytotoxic agents for the treatment of metastatic malignant melanoma: temozolomide and related alkylating agents in combination with guanine analogues to abrogate drug resistance.
Forum (Genoa, Italy) 2000;10(3):274-85.
2000: Brian M Davis; Omer N Koç; Stanton L Gerson
Limiting numbers of G156A O(6)-methylguanine-DNA methyltransferase-transduced marrow progenitors repopulate nonmyeloablated mice after drug selection.
Blood 2000;95(10):3078-84.
2000: Omer N Koç; Stanton L Gerson; Brenda W Cooper; M Laughlin; Howard J Meyerson; LA Kutteh; Robert M Fox; Emese Szekely; N Tainer; Hillard M Lazarus
Randomized cross-over trial of progenitor-cell mobilization: high-dose cyclophosphamide plus granulocyte colony-stimulating factor (G-CSF) versus granulocyte-macrophage colony-stimulating factor plus G-CSF.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(9):1824-30.
2000: Xiusheng Qin; D Shibata; Stanton L Gerson
Heterozygous DNA mismatch repair gene PMS2-knockout mice are susceptible to intestinal tumor induction with N-methyl-N-nitrosourea.
Carcinogenesis 2000;21(4):833-8.
2000: Hillard M Lazarus; Andrew L Pecora; Thomas C Shea; Omer N Koç; J M White; Don A Gabriel; Brenda W Cooper; Stanton L Gerson; M Krieger; A P Sing
CD34+ selection of hematopoietic blood cell collections and autotransplantation in lymphoma: overnight storage of cells at 4 degrees C does not affect outcome.
Bone marrow transplantation 2000;25(5):559-66.
2000: Pietro Taverna; Lili Liu; A J Hanson; A Monks; Stanton L Gerson
Characterization of MLH1 and MSH2 DNA mismatch repair proteins in cell lines of the NCI anticancer drug screen.
Cancer chemotherapy and pharmacology 2000;46(6):507-16.
2000: Omer N Koç; Stanton L Gerson; Brenda W Cooper; S M Dyhouse; Stephen E Haynesworth; Arnold I Caplan; Hillard M Lazarus
Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(2):307-16.
1999: Brian M Davis; Justin Roth; Lili Liu; M Xu-Welliver; Anthony E Pegg; Stanton L Gerson
Characterization of the P140K, PVP(138-140)MLK, and G156A O6-methylguanine-DNA methyltransferase mutants: implications for drug resistance gene therapy.
Human gene therapy 1999;10(17):2769-78.
1999: Omer N Koç; Charles Peters; Patrick R Aubourg; S Raghavan; S Dyhouse; Rita DeGasperi; E H Kolodny; Y B Yoseph; Stanton L Gerson; H M Lazarus; Arnold I Caplan; Paul A Watkins; William Krivit
Bone marrow-derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases.
Experimental hematology 1999;27(11):1675-81.
1999: Jane S Reese; Omer N Koç; Stanton L Gerson
Human mesenchymal stem cells provide stromal support for efficient CD34+ transduction.
Journal of hematotherapy & stem cell research 1999;8(5):515-23.
1999: Lili Liu; Pietro Taverna; Cecilia M Whitacre; Satadal Chatterjee; Stanton L Gerson
Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10):2908-17.
1999: Xiusheng Qin; Hang Zhou; Lili Liu; Stanton L Gerson
Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis.
Carcinogenesis 1999;20(9):1667-73.
1999: Xiusheng Qin; Lili Liu; Stanton L Gerson
Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT.
Oncogene 1999;18(30):4394-400.
1999: Omer N Koç; Jane S Reese; Emese Szekely; Stanton L Gerson
Human long-term culture initiating cells are sensitive to benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea and protected after mutant (G156A) methylguanine methyltransferase gene transfer.
Cancer gene therapy 1999;6(4):340-8.
1999: E Allay; Martina L Veigl; Stanton L Gerson
Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea.
Oncogene 1999;18(25):3783-7.
1999: Timothy P Spiro; Stanton L Gerson; Lili Liu; Susan Majka; John R Haaga; Charles L Hoppel; Stephen T Ingalls; J M Pluda; James Willson
O6-benzylguanine: a clinical trial establishing the biochemical modulatory dose in tumor tissue for alkyltransferase-directed DNA repair.
Cancer research 1999;59(10):2402-10.
1999: Omer N Koç; Jane S Reese; Brian M Davis; Lili Liu; K J Majczenko; Stanton L Gerson
DeltaMGMT-transduced bone marrow infusion increases tolerance to O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea and allows intensive therapy of 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant human colon cancer xenografts.
Human gene therapy 1999;10(6):1021-30.
1999: Stanton L Gerson; Jane E Schupp; Lili Liu; Anthony E Pegg; S Srinivasen
Leukocyte O6-alkylguanine-DNA alkyltransferase from human donors is uniformly sensitive to O6-benzylguanine.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(3):521-4.
1999: Lili Liu; Xiusheng Qin; Stanton L Gerson
Reduced lung tumorigenesis in human methylguanine DNA--methyltransferase transgenic mice achieved by expression of transgene within the target cell.
Carcinogenesis 1999;20(2):279-84.
1999: W P Phillips; Stanton L Gerson
Acquired resistance to O6-benzylguanine plus chloroethylnitrosoureas in human breast cancer.
Cancer chemotherapy and pharmacology 1999;44(4):319-26.
1999: Brian M Davis; Omer N Koç; Jane S Reese; Stanton L Gerson
O6-benzylguanine-resistant mutant MGMT genes improve hematopoietic cell tolerance to alkylating agents.
Progress in experimental tumor research 1999;36():65-81.
1999: Jane S Reese; Brian M Davis; Lili Liu; Stanton L Gerson
Simultaneous protection of G156A methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and sensitization of tumor cells using O6-benzylguanine and temozolomide.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):163-9.
1998: Manas Majumdar; MA Thiede; Joseph Mosca; Mark Moorman; Stanton L Gerson
Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells.
Journal of cellular physiology 1998;176(1):57-66.
1998: Lili Liu; K Lee; Jane E Schupp; Omer N Koç; Stanton L Gerson
Heterogeneity of O6-alkylguanine-DNA-alkyltransferase measured by flow cytometric analysis in blood and bone marrow mononuclear cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):475-81.
1998: Omer N Koç; Stanton L Gerson; Gordon L Phillips; Brenda W Cooper; LA Kutteh; Gary Van Zant; Donna Reece; Robert M Fox; Jane E Schupp; N Tainer; Hillard M Lazarus
Autologous CD34+ cell transplantation for patients with advanced lymphoma: effects of overnight storage on peripheral blood progenitor cell enrichment and engraftment.
Bone marrow transplantation 1998;21(4):337-43.
1997: T L Stefan; Stephen T Ingalls; Paul E Minkler; James Willson; Stanton L Gerson; Timothy P Spiro; Charles L Hoppel
Simultaneous determination of O6-benzylguanine and 8-oxo-O6-benzylguanine in human plasma by reversed-phase high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 1997;704(1-2):289-98.
1997: Brian M Davis; Jane S Reese; Omer N Koç; K Lee; Jane E Schupp; Stanton L Gerson
Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.
Cancer research 1997;57(22):5093-9.
1997: W P Phillips; James Willson; Sanford D Markowitz; Elizabeth Zborowska; N H Zaidi; Lili Liu; Nahida H Gordon; Stanton L Gerson
O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogenous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU.
Cancer research 1997;57(21):4817-23.
1997: E Allay; Jane S Reese; E A McGuire; Omer N Koç; N Sedransk; Stanton L Gerson
Potentiation of lymphomagenesis by methylnitrosourea in mice transgenic for LMO1 is blocked by O6-alkylguanine DNA-alkyltransferase.
Oncogene 1997;15(17):2127-32.
1997: Hillard M Lazarus; Stephen E Haynesworth; Stanton L Gerson; Arnold I Caplan
Human bone marrow-derived mesenchymal (stromal) progenitor cells (MPCs) cannot be recovered from peripheral blood progenitor cell collections.
Journal of hematotherapy 1997;6(5):447-55.
1997: J A Allay; B M Davis; Stanton L Gerson
Human alkyltransferase-transduced murine myeloid progenitors are enriched in vivo by BCNU treatment of transplanted mice.
Experimental hematology 1997;25(10):1069-76.
1997: J A Allay; James E Dennis; Stephen E Haynesworth; Manas Majumdar; D W Clapp; L D Shultz; Arnold I Caplan; Stanton L Gerson
LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors.
Human gene therapy 1997;8(12):1417-27.
1997: Brenda W Cooper; Wilma Mackay; Stanton L Gerson; Hillard M Lazarus
Erythroid burst-forming units (BFU-E) predict hematopoietic recovery after peripheral blood progenitor cell transplantation in patients with advanced breast cancer.
Bone marrow transplantation 1997;19(11):1089-94.
1996: Lili Liu; Sanford Markowitz; Stanton L Gerson
Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea.
Cancer research 1996;56(23):5375-9.
1996: Jane S Reese; Omer N Koç; K M Lee; Lili Liu; J A Allay; W P Phillips; Stanton L Gerson
Retroviral transduction of a mutant methylguanine DNA methyltransferase gene into human CD34 cells confers resistance to O6-benzylguanine plus 1,3-bis(2-chloroethyl)-1-nitrosourea.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):14088-93.
1996: Brian M Davis; O N Koc; K Lee; Stanton L Gerson
Current progress in the gene therapy of cancer.
Current opinion in oncology 1996;8(6):499-508.
1996: A A Ross; T J Layton; A B Ostrander; J L Passos-Coelho; JANICE DAVIS SPROUL; A M Huelskamp; Stephen J Noga; Nancy E Davidson; M J Kennedy; Brenda W Cooper; Stanton L Gerson; Hillard M Lazarus; K Holland; Stefan Gluck; T J Moss; A Kaubish; Linda Vahdat; K Antman
Comparative analysis of breast cancer contamination in mobilized and nonmobilized hematopoietic grafts.
Journal of hematotherapy 1996;5(5):549-52.
1996: Stanton L Gerson; W Phillips; M Kastan; L L Dumenco; C Donovan
Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6-benzylguanine plus BCNU.
Blood 1996;88(5):1649-55.
1996: J A Allay; Omer N Koç; Brian M Davis; Stanton L Gerson
Retroviral-mediated gene transduction of human alkyltransferase complementary DNA confers nitrosourea resistance to human hematopoietic progenitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(8):1353-9.
1996: T L Stefan; Stephen T Ingalls; Stanton L Gerson; James Willson; Charles L Hoppel
Determination of O6-benzylguanine in human plasma by reversed-phase high-performance liquid chromatography.
Journal of chromatography. B, Biomedical applications 1996;681(2):331-8.
1996: G R Roush; NS Rosenthal; Stanton L Gerson; E M Toy; P McCarthy; N V Hirschler; Roslyn Yomtovian
An unusual case of autoimmune hemolytic anemia with reticulocytopenia, erythroid dysplasia, and an IgG2 autoanti-U.
Transfusion 1996;36(6):575-80.
1996: Lili Liu; K Lee; E Wasan; Stanton L Gerson
Differential sensitivity of human and mouse alkyltransferase to O6-benzylguanine using a transgenic model.
Cancer research 1996;56(8):1880-5.
1996: N H Zaidi; Lili Liu; Stanton L Gerson
Quantitative immunohistochemical estimates of O6-alkylguanine-DNA alkyltransferase expression in normal and malignant human colon.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(3):577-84.
1996: Omer N Koç; J A Allay; K Lee; Brian M Davis; Jane S Reese; Stanton L Gerson
Transfer of drug resistance genes into hematopoietic progenitors to improve chemotherapy tolerance.
Seminars in oncology 1996;23(1):46-65.
1996: Omer N Koç; W P Phillips; K Lee; Lili Liu; N H Zaidi; J A Allay; Stanton L Gerson
Role of DNA repair in resistance to drugs that alkylate O6 of guanine.
Cancer treatment and research 1996;87():123-46.
1995: Hillard M Lazarus; Stephen E Haynesworth; Stanton L Gerson; NS Rosenthal; Arnold I Caplan
Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use.
Bone marrow transplantation 1995;16(4):557-64.
1995: James Willson; John R Haaga; J E Trey; T A Stellato; Nahida H Gordon; Stanton L Gerson
Modulation of O6-alkylguanine alkyltransferase-directed DNA repair in metastatic colon cancers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995;13(9):2301-8.
1995: J A Allay; L L Dumenco; O N Koc; Lili Liu; Stanton L Gerson
Retroviral transduction and expression of the human alkyltransferase cDNA provides nitrosourea resistance to hematopoietic cells.
Blood 1995;85(11):3342-51.
1995: Stanton L Gerson; E Allay; K Vitantonio; L L Dumenco
Determinants of O6-alkylguanine-DNA alkyltransferase activity in human colon cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(5):519-25.
1995: N H Zaidi; E Allay; T C Ayi; Benjamin F L Li; L L Dumenco; Man-Sun Sy; Stanton L Gerson
The immature thymocyte is protected from N-methylnitrosourea-induced lymphoma by the human MGMT-CD2 transgene.
Carcinogenesis 1995;16(5):1047-53.
1995: Stanton L Gerson; James Willson
O6-alkylguanine-DNA alkyltransferase. A target for the modulation of drug resistance.
Hematology/oncology clinics of North America 1995;9(2):431-50.
1995: N H Zaidi; Theresa P Pretlow; Mary Ann O'Riordan; L L Dumenco; E Allay; Stanton L Gerson
Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon.
Carcinogenesis 1995;16(3):451-6.
1994: Lili Liu; E Allay; L L Dumenco; Stanton L Gerson
Rapid repair of O6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas.
Cancer research 1994;54(17):4648-52.
1994: Stanton L Gerson
G-CSF and the management of clozapine-induced agranulocytosis.
The Journal of clinical psychiatry 1994;55 Suppl B():139-42.
1994: Stanton L Gerson; Sosamma J Berger; M E Varnes; C Donovan
Combined depletion of O6-alkylguanine-DNA alkyltransferase and glutathione to modulate nitrosourea resistance in breast cancer.
Biochemical pharmacology 1994;48(3):543-8.
1994: Stanton L Gerson; N H Zaidi; L L Dumenco; E Allay; C Y Fan; Lili Liu; P J O'Connor
Alkyltransferase transgenic mice: probes of chemical carcinogenesis.
Mutation research 1994;307(2):541-55.
1994: Stanton L Gerson; C Arce; Herbert Y Meltzer
N-desmethylclozapine: a clozapine metabolite that suppresses haemopoiesis.
British journal of haematology 1994;86(3):555-61.
1993: D T Minnick; Stanton L Gerson; L L Dumenco; Martina L Veigl; W David Sedwick
Specificity of bischloroethylnitrosourea-induced mutation in a Chinese hamster ovary cell line transformed to express human O6-alkylguanine-DNA alkyltransferase.
Cancer research 1993;53(5):997-1003.
1993: Stanton L Gerson; Elizabeth Zborowska; K Norton; Nahida H Gordon; James Willson
Synergistic efficacy of O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in a human colon cancer xenograft completely resistant to BCNU alone.
Biochemical pharmacology 1993;45(2):483-91.
1993: L L Dumenco; E Allay; K Norton; Stanton L Gerson
The prevention of thymic lymphomas in transgenic mice by human O6-alkylguanine-DNA alkyltransferase.
Science (New York, N.Y.) 1993;259(5092):219-22.
1992: Stanton L Gerson; Nathan A Berger; C Arce; S J Petzold; James Willson
Modulation of nitrosourea resistance in human colon cancer by O6-methylguanine.
Biochemical pharmacology 1992;43(5):1101-7.
1992: Stanton L Gerson; Herbert Y Meltzer
Mechanisms of clozapine-induced agranulocytosis.
Drug safety : an international journal of medical toxicology and drug experience 1992;7 Suppl 1():17-25.
1991: D W Clapp; L L Dumenco; Maria Hatzoglou; Stanton L Gerson
Fetal liver hematopoietic stem cells as a target for in utero retroviral gene transfer.
Blood 1991;78(4):1132-9.
1991: L L Dumenco; C Arce; K Norton; J Yun; Thomas E Wagner; Stanton L Gerson
Enhanced repair of O6-methylguanine DNA adducts in the liver of transgenic mice expressing the ada gene.
Cancer research 1991;51(13):3391-8.
1990: I K Lim; L L Dumenco; Maria Hatzoglou; Richard W Hanson; Stanton L Gerson
Increased drug resistance following retroviral gene transfer of a chimeric P-enolpyruvate carboxykinase (GTP)-bacterial O6-alkylguanine-DNA alkyltransferase gene into NRK cells.
Carcinogenesis 1990;11(5):737-43.
1990: I K Lim; L L Dumenco; J Yun; C Donovan; B Warman; N Gorodetzkaya; Thomas E Wagner; D W Clapp; Richard W Hanson; Stanton L Gerson
High level, regulated expression of the chimeric P-enolpyruvate carboxykinase (GTP)-bacterial O6-alkylguanine-DNA alkyltransferase (ada) gene in transgenic mice.
Cancer research 1990;50(6):1701-8.
1990: L L Dumenco; C Donovan; B Warman; D W Clapp; I K Lim; J Yun; Thomas E Wagner; Richard W Hanson; Stanton L Gerson
Transgenic mice expressing the bacterial O6 alkylguanine-DNA alkyltransferase gene: an animal model to study the role of DNA repair in the carcinogenesis of N-nitroso compounds.
Progress in clinical and biological research 1990;340A():369-78.
1989: Hillard M Lazarus; R J Creger; Stanton L Gerson
Infectious emergencies in oncology patients.
Seminars in oncology 1989;16(6):543-60.
1989: Stanton L Gerson; Hillard M Lazarus
Hematopoietic emergencies.
Seminars in oncology 1989;16(6):532-42.
1989: L L Dumenco; B Warman; Maria Hatzoglou; I K Lim; Sherry L Abboud; Stanton L Gerson
Increase in nitrosourea resistance in mammalian cells by retrovirally mediated gene transfer of bacterial O6-alkylguanine-DNA alkyltransferase.
Cancer research 1989;49(21):6044-51.
1989: E U Dexter; T S Yamashita; C Donovan; Stanton L Gerson
Modulation of O6-alkylguanine-DNA alkyltransferase in rats following intravenous administration of O6-methylguanine.
Cancer research 1989;49(13):3520-4.
1989: D W Clapp; Jill Baley; Stanton L Gerson
Gestational age-dependent changes in circulating hematopoietic stem cells in newborn infants.
The Journal of laboratory and clinical medicine 1989;113(4):422-7.
1988: Stanton L Gerson
Regeneration of O6-alkylguanine-DNA alkyltransferase in human lymphocytes after nitrosourea exposure.
Cancer research 1988;48(18):5368-73.
1988: Stanton L Gerson; J E Trey
Modulation of nitrosourea resistance in myeloid leukemias.
Blood 1988;71(5):1487-94.
1988: Stanton L Gerson; J E Trey; K Miller
Potentiation of nitrosourea cytotoxicity in human leukemic cells by inactivation of O6-alkylguanine-DNA alkyltransferase.
Cancer research 1988;48(6):1521-7.
1988: J Stein; S Strandjord; U Saarinen; Phyllis I Warkentin; Stanton L Gerson; H Lazarus; Daniel Von Hoff; P Coccia; Nai-Kong V Cheung
In vitro treatment of autologous bone marrow for neuroblastoma patients with anti GD2 monoclonal antibody and human complement: a pilot study.
Progress in clinical and biological research 1988;271():237-48.
1987: Nathan A Berger; S J Berger; Stanton L Gerson
DNA repair, ADP-ribosylation and pyridine nucleotide metabolism as targets for cancer chemotherapy.
Anti-cancer drug design 1987;2(2):203-9.