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Lena Gerwick

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Marine Biology

Chemicals & Drugs

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Publications

TOP 3
Jennifer Gehret McCarthy; David H Sherman; Peter Wipf; Eli B Eisman; Lena Gerwick; William H Gerwick; Sarang Kulkarni; Janet L Smith
Structural basis of functional group activation by sulfotransferases in complex metabolic pathways.
Marcy J Balunas; Niclas Engene; Lena Gerwick; Manuel F Grosso; Dennis E Kyle; Kerry L McPhail; Laura M Pineda; Carmenza Spadafora; Kevin Tidgewell; Francisco A Villa; William H Gerwick
Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins.
Hyukjae Choi; Lena Gerwick; Tara Byrum; Samantha J Mascuch; Linda B Preskitt; David C Rowley; Jennifer E Smith; Margaret E Teasdale; Francisco A Villa; William H Gerwick
Honaucins A-C, potent inhibitors of inflammation and bacterial quorum sensing: synthetic derivatives and structure-activity relationships.

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All Publications

2012: Jennifer Gehret McCarthy; David H Sherman; Peter Wipf; Eli B Eisman; Lena Gerwick; William H Gerwick; Sarang Kulkarni; Janet L Smith
Structural basis of functional group activation by sulfotransferases in complex metabolic pathways.
ACS chemical biology 2012;7(12):1994-2003.
2012: Marcy J Balunas; Niclas Engene; Lena Gerwick; Manuel F Grosso; Dennis E Kyle; Kerry L McPhail; Laura M Pineda; Carmenza Spadafora; Kevin Tidgewell; Francisco A Villa; William H Gerwick
Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins.
Organic letters 2012;14(15):3878-81.
2012: Hyukjae Choi; Lena Gerwick; Tara Byrum; Samantha J Mascuch; Linda B Preskitt; David C Rowley; Jennifer E Smith; Margaret E Teasdale; Francisco A Villa; William H Gerwick
Honaucins A-C, potent inhibitors of inflammation and bacterial quorum sensing: synthetic derivatives and structure-activity relationships.
Chemistry & biology 2012;19(5):589-98.
2012: Adam C Jones; Bradley S Moore; Sabine Ottilie; Daniel J Edwards; Alessandra S Eustáquio; Lena Gerwick; William H Gerwick
Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A.
The FEBS journal 2012;279(7):1243-51.
2012: Tristan M Carland; Jeffrey B Locke; Victor Nizet; Lena Gerwick
Differential expression and intrachromosomal evolution of the sghC1q genes in zebrafish (Danio rerio).
Developmental and comparative immunology 2012;36(1):31-8.
2011: Niclas Engene; Eduardo Esquenazi; Lena Gerwick; Tara Byrum; Zhengyu Cao; Hyukjae Choi; Pieter dorrestein; Thomas F Murray; Francisco A Villa; William H Gerwick
Phylogeny-guided isolation of ethyl tumonoate A from the marine cyanobacterium cf. Oscillatoria margaritifera.
Journal of natural products 2011;74(8):1737-43.
2011: Daniel W Udwary; Erin A Gontang; Adam C Jones; Carla S Jones; Andrew W Schultz; Jaclyn M Winter; Jane Y Yang; Nicholas Beauchemin; Todd L Capson; Benjamin R Clark; Eduardo Esquenazi; Alessandra S Eustáquio; Kelle Freel; Lena Gerwick; William H Gerwick; David Gonzalez; Wei-Ting Liu; Karla L Malloy; Katherine N Maloney; Markus Nett; Joshawna K Nunnery; Kevin Penn; Alejandra Prieto-Davo; Thomas L Simmons; Sara Weitz; Micheal C Wilson; Louis S Tisa; Pieter dorrestein; Bradley S Moore
Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses.
Applied and environmental microbiology 2011;77(11):3617-25.
2011: Adam C Jones; Emily A Monroe; Sheila Podell; Wolfgang R Hess; Sven Klages; Eduardo Esquenazi; Sherry Niessen; Heather Hoover; Michael Rothmann; Roger S Lasken; John R Yates; Richard Reinhardt; Michael Kube; Michael D Burkart; Eric E Allen; Pieter dorrestein; William H Gerwick; Lena Gerwick
Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(21):8815-20.
2011: Karla L Malloy; Francisco A Villa; Niclas Engene; Teatulohi Matainaho; Lena Gerwick; William H Gerwick
Malyngamide 2, an oxidized lipopeptide with nitric oxide inhibiting activity from a Papua New Guinea marine cyanobacterium.
Journal of natural products 2011;74(1):95-8.
2011: Rashel V Grindberg; Thomas Ishoey; Dumitru Brinza; Eduardo Esquenazi; R Cameron Coates; Wei-Ting Liu; Lena Gerwick; Pieter dorrestein; Pavel A Pevzner; Roger Lasken; William H Gerwick
Single cell genome amplification accelerates identification of the apratoxin biosynthetic pathway from a complex microbial assemblage.
PloS one 2011;6(4):e18565.
2010: Tristan M Carland; Lena Gerwick
The C1q domain containing proteins: Where do they come from and what do they do?
Developmental and comparative immunology 2010;34(8):785-90.
2010: Adam C Jones; Emily A Monroe; Eli B Eisman; Lena Gerwick; David H Sherman; William H Gerwick
The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria.
Natural product reports 2010;27(7):1048-65.
2010: Francisco A Villa; Lena Gerwick
Marine natural product drug discovery: Leads for treatment of inflammation, cancer, infections, and neurological disorders.
Immunopharmacology and immunotoxicology 2010;32(2):228-37.
2010: Francisco A Villa; Kelly Lieske; Lena Gerwick
Selective MyD88-dependent pathway inhibition by the cyanobacterial natural product malyngamide F acetate.
European journal of pharmacology 2010;629(1-3):140-6.
2009: Adam C Jones; Lena Gerwick; David Gonzalez; Pieter C Dorrestein; William H Gerwick
Transcriptional analysis of the jamaicamide gene cluster from the marine cyanobacterium Lyngbya majuscula and identification of possible regulatory proteins.
BMC microbiology 2009;9():247.
2008: T Luke Simmons; Niclas Engene; Luis David Ureña; Luz I Romero; Eduardo Ortega-Barría; Lena Gerwick; William H Gerwick
Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis.
Journal of natural products 2008;71(9):1544-50.
2007: T S Momoda; A R Schwindt; Grant W Feist; Lena Gerwick; Christopher J Bayne; Carl B Schreck
Gene expression in the liver of rainbow trout, Oncorhynchus mykiss, during the stress response.
Comparative biochemistry and physiology. Part D, Genomics & proteomics 2007;2(4):303-15.
2007: Lena Gerwick; Graham E Corley-Smith; Christopher J Bayne
Gene transcript changes in individual rainbow trout livers following an inflammatory stimulus.
Fish & shellfish immunology 2007;22(3):157-71.
2006: Christopher J Bayne; Lena Gerwick; Paul A Wheeler; Gary H Thorgaard
Transcriptome profiles of livers and kidneys from three rainbow trout (Oncorhynchus mykiss) clonal lines distinguish stocks from three allopatric populations.
Comparative biochemistry and physiology. Part D, Genomics & proteomics 2006;1(4):396-403.
2005: Susan C Tilton; Lena Gerwick; Jerry D Hendricks; Caprice S Rosato; Graham E Corley-Smith; Scott A Givan; George S Bailey; Christopher J Bayne; David E Williams
Use of a rainbow trout oligonucleotide microarray to determine transcriptional patterns in aflatoxin B1-induced hepatocellular carcinoma compared to adjacent liver.
Toxicological sciences : an official journal of the Society of Toxicology 2005;88(2):319-30.
2003: Kazuhiro Fujiki; Lena Gerwick; Christopher J Bayne; Leslie Mitchell; Julie Gauley; Niels C Bols; Brian Dixon
Molecular cloning and characterization of rainbow trout (Oncorhynchus mykiss) CCAAT/enhancer binding protein beta.
Immunogenetics 2003;55(4):253-61.
2002: Lena Gerwick; R Steinhauer; SE LaPatra; T Sandell; J Ortuno; N Hajiseyedjavadi; Christopher J Bayne
The acute phase response of rainbow trout (Oncorhynchus mykiss) plasma proteins to viral, bacterial and fungal inflammatory agents.
Fish & shellfish immunology 2002;12(3):229-42.
2001: Christopher J Bayne; Lena Gerwick
The acute phase response and innate immunity of fish.
Developmental and comparative immunology 2001;25(8-9):725-43.
2001: Christopher J Bayne; Lena Gerwick; Kazuhiro Fujiki; Miki Nakao; Tomoki Yano
Immune-relevant (including acute phase) genes identified in the livers of rainbow trout, Oncorhynchus mykiss, by means of suppression subtractive hybridization.
Developmental and comparative immunology 2001;25(3):205-17.
2000: Lena Gerwick; WS Reynolds; Christopher J Bayne
A precerebellin-like protein is part of the acute phase response in rainbow trout, Oncorhynchus mykiss.
Developmental and comparative immunology 2000;24(6-7):597-607.
1999: Lena Gerwick; N E Demers; Christopher J Bayne
Modulation of stress hormones in rainbow trout by means of anesthesia, sensory deprivation and receptor blockade.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 1999;124(3):329-34.