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Christian Gespach

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Astrid De Boeck; Hannelore Denys; Christian Gespach; An Hendrix; Karen Hensen; Kathleen Lambein; Dawn Maynard; Patrick Pauwels; Jean-Luc Rummens; Wendy Westbroek; Marc Bracke; Geert Braems; Olivier De Wever
Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling.
Astrid De Boeck; Marc Bracke; Annick Daniëls; Christian Gespach; An Hendrix; Dawn Maynard; Patrick Pauwels; Mieke Van Bockstal; Olivier De Wever
Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression.
Radia Ouelaa-Benslama; Grégoire Prévost; Michèle Sabbah; Marc Bracke; Olivier De Wever; Shahin Emami; An Hendrix; Mien-Chie Hung; Kathleen Lambein; David Land; Annette K Larsen; Christian Gespach
Identification of a GαGβγ, AKT and PKCα signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchymal transition.

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All Publications

2013: Astrid De Boeck; Hannelore Denys; Christian Gespach; An Hendrix; Karen Hensen; Kathleen Lambein; Dawn Maynard; Patrick Pauwels; Jean-Luc Rummens; Wendy Westbroek; Marc Bracke; Geert Braems; Olivier De Wever
Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling.
Gut 2013;62(4):550-60.
2013: Astrid De Boeck; Marc Bracke; Annick Daniëls; Christian Gespach; An Hendrix; Dawn Maynard; Patrick Pauwels; Mieke Van Bockstal; Olivier De Wever
Differential secretome analysis of cancer-associated fibroblasts and bone marrow-derived precursors to identify microenvironmental regulators of colon cancer progression.
Proteomics 2013;13(2):379-88.
2012: Radia Ouelaa-Benslama; Grégoire Prévost; Michèle Sabbah; Marc Bracke; Olivier De Wever; Shahin Emami; An Hendrix; Mien-Chie Hung; Kathleen Lambein; David Land; Annette K Larsen; Christian Gespach
Identification of a GαGβγ, AKT and PKCα signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchymal transition.
International journal of oncology 2012;41(1):189-200.
2012: Joëlle Dupont; Christian Gespach; Bo Ji; Sonia Métayer-Coustard; Christelle Ramé; Brynn Voy; Jean Simon
Characterization of major elements of insulin signaling cascade in chicken adipose tissue: apparent insulin refractoriness.
General and comparative endocrinology 2012;176(1):86-93.
2012: Jean Simon; Sophie Tesseraud; Cedric Cabau; Estelle Cailleau-Audouin; Anne Collin; Sabine Crochet; Michel Derouet; Michel J Duclos; Joëlle Dupont; Christian Gespach; Estelle Godet; Christelle Hennequet-Antier; Sonia Métayer-Coustard; Dragan Milenkovic; Tom E Porter; Nicole Rideau; Larry A Cogburn
Insulin immuno-neutralization in fed chickens: effects on liver and muscle transcriptome.
Physiological genomics 2012;44(5):283-92.
2012: Christian Gespach
Increasing potential of HER3 signaling in colon cancer progression and therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(4):917-9.
2012: An Hendrix; Kathleen Lambein; Patrick Pauwels; Miguel C Seabra; Wendy Westbroek; Marc Bracke; Veronique Cocquyt; Christian Gespach; Olivier De Wever
An immunohistochemical analysis of Rab27B distribution in fetal and adult tissue.
The International journal of developmental biology 2012;56(5):363-8.
2012: Christian Gespach
Guidance for life, cell death, and colorectal neoplasia by netrin dependence receptors.
Advances in cancer research 2012;114():87-186.
2011: Soraya Sin; Akeila Bellahcène; Ivan Bièche; Florian Bonin; Vincent Castronovo; Olivier de Wever; Christian Gespach; François Lallemand; Rosette Lidereau; Didier Meseure; Valérie Petit; Keltouma Driouch
Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis.
Journal of the National Cancer Institute 2011;103(17):1323-37.
2011: Katherine S Lovejoy; Eric Raymond; Maria Serova; Ivan Bieche; Massimo Broggini; Esteban Cvitkovic; Maurizio D'Incalci; Shahin Emami; Eugenio Erba; Sandrine Faivre; Christian Gespach; Stephen J Lippard
Spectrum of cellular responses to pyriplatin, a monofunctional cationic antineoplastic platinum(II) compound, in human cancer cells.
Molecular cancer therapeutics 2011;10(9):1709-19.
2011: Olivier De Wever; Marc Bracke; Christian Gespach; Jean-Claude Michalski; Radia Ouelaa-Benslama; Joëlle Sobczak-Thépot; Dwayne G Stupack; Anne-Sophie Vercoutter-Edouart; Jean Y J Wang; Shahin Emami
Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts.
International journal of oncology 2011;39(2):393-400.
2011: Samir Attoub; Ahmed H Hassan; Barbara Vanhoecke; Rabah Iratni; Takashi Takahashi; Anne-Marie Gaben; Marc Bracke; Salma Awad; Anne John; Hamda Ahmed Kamalboor; Mahmood Ahmed Al Sultan; Kholoud Arafat; Christian Gespach; Georg Petroianu
Inhibition of cell survival, invasion, tumor growth and histone deacetylase activity by the dietary flavonoid luteolin in human epithelioid cancer cells.
European journal of pharmacology 2011;651(1-3):18-25.
2011: Christian Gespach
Signaling networks in cancer--an interview with Christian Gespach. Interview by Olivier De Wever.
The International journal of developmental biology 2011;55(7-9):713-8.
2010: Mathieu Boissan; Olivier De Wever; Floria Lizarraga; Dominique Wendum; Renaud Poincloux; Nicolas Chignard; Christèle Desbois-Mouthon; Sylvie Dufour; Béatrice Nawrocki-Raby; Philippe Birembaut; Marc Bracke; Philippe Chavrier; Christian Gespach; Marie-Lise Lacombe
Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.
Cancer research 2010;70(19):7710-22.
2010: Marco Alifano; Frédérique Souazé; Sandra Dupouy; Sophie Camilleri-Broët; Mohamad Younes; Sadi-Menad Ahmed-Zaïd; Takashi Takahashi; Alessandra Cancellieri; Stefania Damiani; Maurizio Boaron; Philippe Broët; Lance D Miller; Christian Gespach; Jean François Regnard; Patricia Forgez
Neurotensin receptor 1 determines the outcome of non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(17):4401-10.
2010: An Hendrix; Dawn Maynard; Patrick Pauwels; Geert Braems; Hannelore Denys; Rudy Van den Broecke; Jo Lambert; Simon Van Belle; Veronique Cocquyt; Christian Gespach; Marc Bracke; Miguel C Seabra; William A Gahl; Olivier De Wever; Wendy Westbroek
Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis.
Journal of the National Cancer Institute 2010;102(12):866-80.
2010: Anne-Frédérique Dessein; Laurence Stechly; Nicolas Jonckheere; Patrick Dumont; didier monte; Emmanuelle Leteurtre; Stéphanie Truant; François-René Pruvot; Martin Figeac; Mohamed Hebbar; Charles-Henri Lecellier; Thécla Lesuffleur; Rodrigue Dessein; Georges Grard; Marie-José Dejonghe; Yvan de Launoit; Yasuhiro Furuichi; Grégoire Prévost; Nicole Porchet; Christian Gespach; Guillemette Huet
Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells.
Cancer research 2010;70(11):4644-54.
2010: Maria Serova; Lucile Astorgues-Xerri; Ivan Bieche; Sebastien Albert; Michel Vidaud; Karim Benhadji; Shahin Emami; Dominique Vidaud; Pascal Hammel; Nathalie Theou-Anton; Christian Gespach; Sandrine Faivre; Eric Raymond
Epithelial-to-mesenchymal transition and oncogenic Ras expression in resistance to the protein kinase Cbeta inhibitor enzastaurin in colon cancer cells.
Molecular cancer therapeutics 2010;9(5):1308-17.
2010: Olivier De Wever; An Hendrix; Astrid De Boeck; Wendy Westbroek; Geert Braems; Shahin Emami; Michle Sabbah; Christian Gespach; Marc Bracke
Modeling and quantification of cancer cell invasion through collagen type I matrices.
The International journal of developmental biology 2010;54(5):887-96.
2009: Mohammed Akli Ayoub; Marjorie Damian; Christian Gespach; Eric Ferrandis; Olivier Lavergne; Olivier De Wever; Jean-Louis Banères; Jean-Philippe Pin; Grégoire Pierre Prévost
Inhibition of heterotrimeric G protein signaling by a small molecule acting on Galpha subunit.
The Journal of biological chemistry 2009;284(42):29136-45.
2009: Sandra Dupouy; Véronique Viardot-Foucault; Marco Alifano; Frédérique Souazé; Geneviève Plu-Bureau; Marc Chaouat; Anne Lavaur; Danielle Hugol; Christian Gespach; anne Gompel; Patricia Forgez
The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression.
PloS one 2009;4(1):e4223.
2008: Jean-Pierre Roperch; Karima El Ouadrani; Ann Hendrix; Shahin Emami; Olivier De Wever; Gerry Melino; Christian Gespach
Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73alpha tumor suppressor.
Cancer research 2008;68(20):8231-9.
2008: Samir Attoub; Olivier De Wever; Eric Bruyneel; Marc Mareel; Christian Gespach
The transforming functions of PI3-kinase-gamma are linked to disruption of intercellular adhesion and promotion of cancer cell invasion.
Annals of the New York Academy of Sciences 2008;1138():204-13.
2008: Olivier De Wever; Patrick Pauwels; Bram De Craene; Michèle Sabbah; Shahin Emami; Gérard Redeuilh; Christian Gespach; Marc Bracke; Geert Berx
Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front.
Histochemistry and cell biology 2008;130(3):481-94.
2008: Hannelore Denys; Lara Derycke; An Hendrix; Wendy Westbroek; Alexander Gheldof; Kishan Narine; Patrick Pauwels; Christian Gespach; Marc Bracke; Olivier De Wever
Differential impact of TGF-beta and EGF on fibroblast differentiation and invasion reciprocally promotes colon cancer cell invasion.
Cancer letters 2008;266(2):263-74.
2008: Michèle Sabbah; Shahin Emami; Gérard Redeuilh; Sylvia Julien; Grégoire Prévost; Amazia Zimber; Radia Ouelaa; Marc Bracke; Olivier De Wever; Christian Gespach
Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2008;11(4-5):123-51.
2008: Amazia Zimber; Christian Gespach
Bile acids and derivatives, their nuclear receptors FXR, PXR and ligands: role in health and disease and their therapeutic potential.
Anti-cancer agents in medicinal chemistry 2008;8(5):540-63.
2008: Joëlle Dupont; Sophie Tesseraud; Michel Derouet; Anne Collin; Nicole Rideau; Sabine Crochet; ESTELLE GODET; Estelle Cailleau-Audouin; Sonia Métayer-Coustard; Michel J Duclos; Christian Gespach; Tom E Porter; Larry A Cogburn; Jean Simon
Insulin immuno-neutralization in chicken: effects on insulin signaling and gene expression in liver and muscle.
The Journal of endocrinology 2008;197(3):531-42.
2008: Asmaà Fritah; Cécile Saucier; Olivier De Wever; Marc Bracke; Ivan Bièche; Rosette Lidereau; Christian Gespach; Sylvain Drouot; Gérard Redeuilh; Michèle Sabbah
Role of WISP-2/CCN5 in the maintenance of a differentiated and noninvasive phenotype in human breast cancer cells.
Molecular and cellular biology 2008;28(3):1114-23.
2007: Severine Van Slambrouck; Clara Grijelmo; Olivier De Wever; Erik Bruyneel; Shahin Emami; Christian Gespach; Wim F A Steelant
Activation of the FAK-src molecular scaffolds and p130Cas-JNK signaling cascades by alpha1-integrins during colon cancer cell invasion.
International journal of oncology 2007;31(6):1501-8.
2007: S Moniz; F Veríssimo; Paulo Matos; R Brazão; E Silva; L Kotelevets; L Kotevelets; Eric Chastre; Christian Gespach; peter Jordan
Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2.
Oncogene 2007;26(41):6071-81.
2007: Sylvie Rodrigues; Olivier De Wever; Erik Bruyneel; Robert J. Rooney; Christian Gespach
Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasis.
Oncogene 2007;26(38):5615-25.
2007: Clara Grijelmo; Christelle Rodrigue; Magalie Svrcek; Erik Bruyneel; An Hendrix; Olivier De Wever; Christian Gespach
Proinvasive activity of BMP-7 through SMAD4/src-independent and ERK/Rac/JNK-dependent signaling pathways in colon cancer cells.
Cellular signalling 2007;19(8):1722-32.
2007: J Ewald; Christelle M Rodrigue; Najat Mourra; jeremie lefevre; Jean-François Fléjou; Emmanuel Tiret; Christian Gespach; Yann Parc
Immunohistochemical staining for mismatch repair proteins, and its relevance in the diagnosis of hereditary non-polyposis colorectal cancer.
The British journal of surgery 2007;94(8):1020-7.
2007: Frank Gieseler; Inke Lühr; Thomas Kunze; Christoph Mundhenke; Nicolai Maass; Tobias Erhart; Momme Denker; Dennis Beckmann; Markus Tiemann; Christoph Schulte; Peter Dohrmann; Françoise Cavaillé; François Godeau; Christian Gespach
Activated coagulation factors in human malignant effusions and their contribution to cancer cell metastasis and therapy.
Thrombosis and haemostasis 2007;97(6):1023-30.
2006: jeremie lefevre; Christelle M Rodrigue; Najat Mourra; Malika Bennis; Jean-François Flejou; Rolland Parc; Emmanuel Tiret; Christian Gespach; Yann Parc
Implication of MYH in colorectal polyposis.
Annals of surgery 2006;244(6):874-9; discussion 879-80.
2006: Sylvie Rodrigues; Christelle M Rodrigue; Samir Attoub; Jean-François Fléjou; Erik Bruyneel; Marc Bracke; Shahin Emami; Christian Gespach
Induction of the adenoma-carcinoma progression and Cdc25A-B phosphatases by the trefoil factor TFF1 in human colon epithelial cells.
Oncogene 2006;25(50):6628-36.
2006: Grégoire Prévost; Marie O Lonchampt; Susan Holbeck; Samir Attoub; Daniel W Zaharevitz; Mike Alley; John Wright; Marie-Christine Brezak; Hélène Coulomb; Ann Savola; Marion Huchet; Sophie Chaumeron; Quang-Dé Nguyen; Patricia Forgez; Erik Bruyneel; Marc Bracke; Eric Ferrandis; Pierre Roubert; Danièle Demarquay; Christian Gespach; Philip G Kasprzyk
Anticancer activity of BIM-46174, a new inhibitor of the heterotrimeric Galpha/Gbetagamma protein complex.
Cancer research 2006;66(18):9227-34.
2006: Quang-Dé Nguyen; Sylvie Rodrigues; Christelle M Rodrigue; Christine Rivat; Clara Grijelmo; Erik Bruyneel; Shahin Emami; Samir Attoub; Christian Gespach
Inhibition of vascular endothelial growth factor (VEGF)-165 and semaphorin 3A-mediated cellular invasion and tumor growth by the VEGF signaling inhibitor ZD4190 in human colon cancer cells and xenografts.
Molecular cancer therapeutics 2006;5(8):2070-7.
2006: Frédérique Souazé; Sandra Dupouy; Véronique Viardot-Foucault; Erik Bruyneel; Samir Attoub; Christian Gespach; anne Gompel; Patricia Forgez
Expression of neurotensin and NT1 receptor in human breast cancer: a potential role in tumor progression.
Cancer research 2006;66(12):6243-9.
2006: Frédérique Souazé; Véronique Viardot-Foucault; Nicolas Roullet; Mireille Toy-Miou-Leong; anne Gompel; Erik Bruyneel; Eva Comperat; Maree C Faux; Marc Mareel; William Rostène; Jean-François Fléjou; Christian Gespach; Patricia Forgez
Neurotensin receptor 1 gene activation by the Tcf/beta-catenin pathway is an early event in human colonic adenomas.
Carcinogenesis 2006;27(4):708-16.
2005: Quang-Dé Nguyen; Olivier De Wever; Erik Bruyneel; An Hendrix; Wan-zhuo Xie; Alain Lombet; Martin Leibl; Marc Mareel; Frank Gieseler; Marc Bracke; Christian Gespach
Commutators of PAR-1 signaling in cancer cell invasion reveal an essential role of the Rho-Rho kinase axis and tumor microenvironment.
Oncogene 2005;24(56):8240-51.
2005: Christian Gespach
Crosstalk between the cell cycle regulator Cdk2 and the Cdx2 tumor suppressor at the proliferation-differentiation interface.
Oncogene 2005;24(54):7953-4.
2005: Pierre-Olivier Lafontaine; Murielle Arnal; Nelly Buron; Eric Solary; Alain M Bron; Bruce R Westley; Felicity E B May; Jacques Bara; Christian Gespach; Catherine Creuzot-Garcher
Trefoil factor family mRNA and protein expression in pterygium.
International journal of oncology 2005;27(4):997-1003.
2005: Valérie Le Meuth-Metzinger; Véronique Philouze-Rome; Laurent Metzinger; Christian Gespach; Paul Guilloteau
Differential activation of adenylate cyclase by secretin and VIP receptors in the calf pancreas.
Pancreas 2005;31(2):174-81.
2005: Anne-Marie Coudray; Christophe Louvet; Michel Kornprobst; Eric Raymond; Thierry André; Christophe Tournigand; Sandrine Faivre; Aimery de Gramont; Annette K Larsen; Christian Gespach
Increased anticancer activity of the thymidylate synthase inhibitor BGC9331 combined with the topoisomerase I inhibitor SN-38 in human colorectal and breast cancer cells: induction of apoptosis and ROCK cleavage through caspase-3-dependent and -independent mechanisms.
International journal of oncology 2005;27(2):553-61.
2005: Christelle M Rodrigue; Françoise Porteu; Nicole Navarro; Erik Bruyneel; Marc Bracke; Paul-Henri Romeo; Christian Gespach; Marie-Claude Garel
The cancer chemopreventive agent resveratrol induces tensin, a cell-matrix adhesion protein with signaling and antitumor activities.
Oncogene 2005;24(20):3274-84.
2005: Christine Rivat; Rivat Christine; Sylvie Rodrigues; Rodrigues Sylvie; Erik Bruyneel; Bruyneel Erik; Geneviève Piétu; Piétu Geneviève; Amélie Robert; Robert Amélie; Gérard Redeuilh; Redeuilh Gérard; Marc Bracke; Bracke Marc; Christian Gespach; Gespach Christian; Samir Attoub; Attoub Samir
Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3) -- and vascular endothelial growth factor-mediated cellular invasion and tumor growth.
Cancer research 2005;65(1):195-202.
2005: Nathalie Le Floch; Christine Rivat; Olivier De Wever; Erik Bruyneel; Marc Mareel; Trevor Dale; Christian Gespach
The proinvasive activity of Wnt-2 is mediated through a noncanonical Wnt pathway coupled to GSK-3beta and c-Jun/AP-1 signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(1):144-6.
2004: Amazia Zimber; Quang-Dé Nguyen; Christian Gespach
Nuclear bodies and compartments: functional roles and cellular signalling in health and disease.
Cellular signalling 2004;16(10):1085-104.
2004: Olivier De Wever; Wendy Westbroek; Alain Verloes; Nele Bloemen; Marc Bracke; Christian Gespach; Erik Bruyneel; Marc Mareel
Critical role of N-cadherin in myofibroblast invasion and migration in vitro stimulated by colon-cancer-cell-derived TGF-beta or wounding.
Journal of cell science 2004;117(Pt 20):4691-703.
2004: Laetitia Mazelin; Agnès Bernet; Christelle Bonod-Bidaud; Laurent Pays; Ségolène Arnaud; Christian Gespach; Dale E Bredesen; Jean-Yves Scoazec; Patrick Mehlen
Netrin-1 controls colorectal tumorigenesis by regulating apoptosis.
Nature 2004;431(7004):80-4.
2004: Michèle Cazillis; Annie-France Bringuier; Danièle Delautier; Maud Buisine; Dominique Bernuau; Christian Gespach; André Groyer
Disruption of MKK4 signaling reveals its tumor-suppressor role in embryonic stem cells.
Oncogene 2004;23(27):4735-44.
2004: Olivier De Wever; Quang-Dé Nguyen; Leen Van Hoorde; Marc Bracke; Erik Bruyneel; Christian Gespach; Marc Mareel
Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent pro-invasive signals to human colon cancer cells through RhoA and Rac.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(9):1016-8.
2004: Sylvie Rodrigues; Erik Bruyneel; Christelle M Rodrigue; Emami Shahin; Christian Gespach
[Cyclooxygenase 2 and carcinogenesis].
Bulletin du cancer 2004;91 Suppl 2():S61-76.
2004: Sylvie Rodrigues; Erik Bruyneel; Christelle M Rodrigue; Emami Shahin; Christian Gespach
[Cyclooxygenase 2 and carcinogenesis].
Bulletin du cancer 2004;91 Spec No():S61-76.
2004: Shahin Emami; Sylvie Rodrigues; Christelle M Rodrigue; Nathalie Le Floch; Christine Rivat; Samir Attoub; Erik Bruyneel; Christian Gespach
Trefoil factor family (TFF) peptides and cancer progression.
Peptides 2004;25(5):885-98.
2004: Christine Rivat; Olivier De Wever; Erik Bruyneel; Marc Mareel; Christian Gespach; Samir Attoub
Disruption of STAT3 signaling leads to tumor cell invasion through alterations of homotypic cell-cell adhesion complexes.
Oncogene 2004;23(19):3317-27.
2004: Frédéric André; Barbara Janssens; Erik Bruyneel; Frans van Roy; Christian Gespach; Marc Mareel; Marc Bracke
Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells.
Oncogene 2004;23(6):1177-86.
2003: Pierre-Olivier Lafontaine; M Arnal; Nelly Buron; Eric Solary; S Lizard; Alain Bron; Jacques Bara; Christian Gespach; Catherine Creuzot-Garcher
[Trefoil factor family gene and peptide expression in pterygium].
Journal français d'ophtalmologie 2003;26(10):1007-14.
2003: Christine Rivat; Nathalie Le Floch; Michèle Sabbah; Isabelle Teyrol; Gérard Redeuilh; Erik Bruyneel; Marc Mareel; Lynn M Matrisian; Howard C Crawford; Christian Gespach; Samir Attoub
Synergistic cooperation between the AP-1 and LEF-1 transcription factors in activation of the matrilysin promoter by the src oncogene: implications in cellular invasion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1721-3.
2003: Sylvie Rodrigues; Samir Attoub; Quang-Dé Nguyen; Erik Bruyneel; Christelle M Rodrigue; Bruce R Westley; Felicity E B May; Lars Thim; Marc Mareel; Shahin Emami; Christian Gespach
Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells.
Oncogene 2003;22(29):4488-97.
2003: Sylvie Rodrigues; Elisabeth Van Aken; Saskia Van Bocxlaer; Samir Attoub; Quang-Dé Nguyen; Erik Bruyneel; Bruce R Westley; Felicity E B May; Lars Thim; Marc Mareel; Christian Gespach; Shahin Emami
Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(1):7-16.
2002: Philip Debruyne; Erik Bruyneel; I-M Karaguni; Xd Li; G Flatau; Oliver Müller; Amazia Zimber; Christian Gespach; Marc M Mareel
Bile acids stimulate invasion and haptotaxis in human colorectal cancer cells through activation of multiple oncogenic signaling pathways.
Oncogene 2002;21(44):6740-50.
2002: Samir Attoub; Christine Rivat; Sylvie Rodrigues; Saskia Van Bocxlaer; Monique Bedin; Erik Bruyneel; Christophe Louvet; Michel Kornprobst; Thierry André; Marc Mareel; Jan Mester; Christian Gespach
The c-kit tyrosine kinase inhibitor STI571 for colorectal cancer therapy.
Cancer research 2002;62(17):4879-83.
2002: Eric Raymond; Christophe Louvet; Christophe Tournigand; Anne-Marie Coudray; Sandrine Faivre; Aimery de Gramont; Christian Gespach
Pemetrexed disodium combined with oxaliplatin, SN38, or 5-fluorouracil, based on the quantitation of drug interactions in human HT29 colon cancer cells.
International journal of oncology 2002;21(2):361-7.
2002: Karine L Régnauld; Quang-Dé Nguyen; Luc Vakaet; Erik Bruyneel; Jean-Marie Launay; Takeshi Endo; Marc Mareel; Christian Gespach; Shahin Emami
G-protein alpha(olf) subunit promotes cellular invasion, survival, and neuroendocrine differentiation in digestive and urogenital epithelial cells.
Oncogene 2002;21(25):4020-31.
2002: Quang-Dé Nguyen; Sandrine Faivre; Erik Bruyneel; Christine Rivat; Minoru Seto; Takeshi Endo; Marc Mareel; Shahin Emami; Christian Gespach
RhoA- and RhoD-dependent regulatory switch of Galpha subunit signaling by PAR-1 receptors in cellular invasion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(6):565-76.
2002: Karine L Régnauld; Emmanuelle Leteurtre; J Silvio Gutkind; Christian Gespach; Shahin Emami
Activation of adenylyl cyclases, regulation of insulin status, and cell survival by G(alpha)olf in pancreatic beta-cells.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;282(3):R870-80.
2001: Maryse Barbier; Samir Attoub; Ronan Calvez; Muriel Laffargue; A Jarry; M Mareel; Fiorella Altruda; Christian Gespach; D Wu; B Lu; Emilio Hirsch; Matthias P Wymann
Tumour biology. Weakening link to colorectal cancer?
Nature 2001;413(6858):796.
2001: Philip Debruyne; Erik Bruyneel; X Li; Amazia Zimber; Christian Gespach; Marc M Mareel
The role of bile acids in carcinogenesis.
Mutation research 2001;480-481():359-69.
2001: Eric Raymond; Sandrine Faivre; Anne-Marie Coudray; Christophe Louvet; Christian Gespach
[Preclinical studies of oxaliplatin in combination chemotherapy].
Bulletin du cancer 2001;88 Spec No():S26-34.
2001: Sandrine Faivre; Karine L Régnauld; Erik Bruyneel; Quang-Dé Nguyen; Marc Mareel; Shahin Emami; Christian Gespach
Suppression of cellular invasion by activated G-protein subunits Galphao, Galphai1, Galphai2, and Galphai3 and sequestration of Gbetagamma.
Molecular pharmacology 2001;60(2):363-72.
2001: Sylvie Rodrigues; Quang-Dé Nguyen; Sandrine Faivre; Erik Bruyneel; Lars Thim; Bruce R Westley; F May; G Flatau; Marc Mareel; Christian Gespach; Shahin Emami
Activation of cellular invasion by trefoil peptides and src is mediated by cyclooxygenase- and thromboxane A2 receptor-dependent signaling pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(9):1517-28.
2001: Abdelilah Wakkach; Eric Chastre; C Bruand; Sylvia Cohen-Kaminsky; S Emami; Christian Gespach; Sonia Berrih-Aknin
Phenotypic and functional characterization of human thymic stromal cell lines.
Cellular and molecular biology (Noisy-le-Grand, France) 2001;47(1):167-78.
2001: Shahin Emami; Nathalie Le Floch; Erik Bruyneel; Lars Thim; F May; Bruce R Westley; M Rio; Marc Mareel; Christian Gespach
Induction of scattering and cellular invasion by trefoil peptides in src- and RhoA-transformed kidney and colonic epithelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(2):351-61.
2000: Paulo Matos; J Skaug; Bárbara Marques; S Beck; F Veríssimo; Christian Gespach; Maria G Boavida; S W Scherer; peter Jordan
Small GTPase Rac1: structure, localization, and expression of the human gene.
Biochemical and biophysical research communications 2000;277(3):741-51.
2000: Samir Attoub; V Noe; Luciano Pirola; Erik Bruyneel; Eric Chastre; Marc Mareel; Matthias P Wymann; Christian Gespach
Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(14):2329-38.
2000: Christophe Louvet; Anne-Marie Coudray; Christophe Tournigand; S Prévost; Eric Raymond; Aimery de Gramont; M Chazard; Christian Gespach
Synergistic antitumoral activity of combined UFT, folinic acid and oxaliplatin against human colorectal HT29 cell xenografts in athymic nude mice.
Anti-cancer drugs 2000;11(7):579-82.
2000: B Z Vider; Amazia Zimber; Eric Chastre; Christian Gespach; M Halperin; P Mashiah; Abraham Yaniv; Arnona Gazit
Deregulated expression of homeobox-containing genes, HOXB6, B8, C8, C9, and Cdx-1, in human colon cancer cell lines.
Biochemical and biophysical research communications 2000;272(2):513-8.
2000: H H Phan; C Boissard; Marcia Pessah; K Regnauld; Shahin Emami; Christian Gespach; GE Rosselin
Decreased ADP-ribosylation of the Galpha(olf) and Galpha(s) subunits by high glucose in pancreatic B-cells.
Biochemical and biophysical research communications 2000;271(1):86-90.
2000: Thierry André; Larissa Kotelevets; JC Vaillant; Anne-Marie Coudray; L Weber; Sophie Prévot; Rolland Parc; Christian Gespach; Eric Chastre
Vegf, Vegf-B, Vegf-C and their receptors KDR, FLT-1 and FLT-4 during the neoplastic progression of human colonic mucosa.
International journal of cancer. Journal international du cancer 2000;86(2):174-81.
2000: A Mazars; C Tournigand; P Mollat; Céline Prunier; Nathalie Ferrand; Marie-Françoise Bourgeade; Christian Gespach; Azeddine Atfi
Differential roles of JNK and Smad2 signaling pathways in the inhibition of c-Myc-induced cell death by TGF-beta.
Oncogene 2000;19(10):1277-87.
2000: Amazia Zimber; A Chedeville; J P Abita; V Barbu; Christian Gespach
Functional interactions between bile acids, all-trans retinoic acid, and 1,25-dihydroxy-vitamin D3 on monocytic differentiation and myeloblastin gene down-regulation in HL60 and THP-1 human leukemia cells.
Cancer research 2000;60(3):672-8.
1999: peter Jordan; R Brazåo; Maria G Boavida; Christian Gespach; Eric Chastre
Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors.
Oncogene 1999;18(48):6835-9.
1999: Abdelilah Wakkach; S Poea; Eric Chastre; Christian Gespach; Florence Lecerf; Sabine De La Porte; Socrates J Tzartos; A Coulombe; Sonia Berrih-Aknin
Establishment of a human thymic myoid cell line. Phenotypic and functional characteristics.
The American journal of pathology 1999;155(4):1229-40.
1999: Céline Prunier; A Mazars; Veerle Noë; Erik Bruyneel; Marc Mareel; Christian Gespach; Azeddine Atfi
Evidence that Smad2 is a tumor suppressor implicated in the control of cellular invasion.
The Journal of biological chemistry 1999;274(33):22919-22.
1999: Azeddine Atfi; Céline Prunier; A Mazars; A S Défachelles; Yvon E Cayre; Christian Gespach; Marie-Françoise Bourgeade
The oncogenic TEL/PDGFR beta fusion protein induces cell death through JNK/SAPK pathway.
Oncogene 1999;18(26):3878-85.
1999: Jacky Marie; Abdelilah Wakkach; Anne-Marie Coudray; Eric Chastre; Sonia Berrih-Aknin; Christian Gespach
Functional expression of receptors for calcitonin gene-related peptide, calcitonin, and vasoactive intestinal peptide in the human thymus and thymomas from myasthenia gravis patients.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(4):2103-12.
1999: O Lorentz; Axelle Cadoret; Isabelle Duluc; Jacqueline Capeau; Christian Gespach; G Cherqui; Jean-Noel Freund
Downregulation of the colon tumour-suppressor homeobox gene Cdx-2 by oncogenic ras.
Oncogene 1999;18(1):87-92.
1999: Veerle Noë; Eric Chastre; Erik Bruyneel; Christian Gespach; Marc Mareel
Extracellular regulation of cancer invasion: the E-cadherin-catenin and other pathways.
Biochemical Society symposium 1999;65():43-62.
1998: Thierry André; Eric Chastre; Larissa Kotelevets; JC Vaillant; Christophe Louvet; Jacques Balosso; E Le Gall; Sophie Prévot; Christian Gespach
[Tumoral angiogenesis: physiopathology, prognostic value and therapeutic perspectives].
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne 1998;19(12):904-13.
1998: A C Prost; Fabrice Ménégaux; P Langlois; J M Vidal; M Koulibaly; J L Jost; J J Duron; Jean-Paul Chigot; P Vayre; André Aurengo; J C Legrand; GE Rosselin; Christian Gespach
Differential transferrin receptor density in human colorectal cancer: A potential probe for diagnosis and therapy.
International journal of oncology 1998;13(4):871-5.
1998: Axelle Cadoret; S Baron-Delage; France Bertrand; M Kornprost; André Groyer; Christian Gespach; Jacqueline Capeau; G Cherqui
Oncogene-induced up-regulation of Caco-2 cell proliferation involves IGF-II gene activation through a protein kinase C-mediated pathway.
Oncogene 1998;17(7):877-87.
1998: Françoise Besançon; Azeddine Atfi; Christian Gespach; Yvon E Cayre; Marie-Françoise Bourgeade
Evidence for a role of NF-kappaB in the survival of hematopoietic cells mediated by interleukin 3 and the oncogenic TEL/platelet-derived growth factor receptor beta fusion protein.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(14):8081-6.
1998: Larissa Kotelevets; Veerle Noë; Erik Bruyneel; E Myssiakine; Eric Chastre; Marc Mareel; Christian Gespach
Inhibition by platelet-activating factor of Src- and hepatocyte growth factor-dependent invasiveness of intestinal and kidney epithelial cells. Phosphatidylinositol 3'-kinase is a critical mediator of tumor invasion.
The Journal of biological chemistry 1998;273(23):14138-45.
1998: Henri Porte; J P Triboulet; Larissa Kotelevets; Fabrice CARRAT; Sophie Prévot; B Nordlinger; Y DiGioia; Alain Wurtz; P Comoglio; Christian Gespach; Eric Chastre
Overexpression of stromelysin-3, BM-40/SPARC, and MET genes in human esophageal carcinoma: implications for prognosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(6):1375-82.
1997: Azeddine Atfi; M Buisine; A Mazars; Christian Gespach
Induction of apoptosis by DPC4, a transcriptional factor regulated by transforming growth factor-beta through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) signaling pathway.
The Journal of biological chemistry 1997;272(40):24731-4.
1997: Eric Raymond; C Buquet-Fagot; S Djelloul; Jan Mester; Esteban Cvitkovic; P Allain; Christophe Louvet; Christian Gespach
Antitumor activity of oxaliplatin in combination with 5-fluorouracil and the thymidylate synthase inhibitor AG337 in human colon, breast and ovarian cancers.
Anti-cancer drugs 1997;8(9):876-85.
1997: Pascal Clerc; Marlène Dufresne; C Saillan; Eric Chastre; Thierry André; Chantal Escrieut; K Kennedy; Nicole Vaysse; Christian Gespach; Daniel Fourmy
Differential expression of the CCK-A and CCK-B/gastrin receptor genes in human cancers of the esophagus, stomach and colon.
International journal of cancer. Journal international du cancer 1997;72(6):931-6.
1997: Pascal Hammel; Marie-Elisabeth Forgue-Lafitte; Philippe Lévy; H Voitot; Valérie Vilgrain; Jean-François Fléjou; G Molas; Christian Gespach; Philippe Ruszniewski; P Bernades; Jacques Bara
Detection of gastric mucins (M1 antigens) in cyst fluid for the diagnosis of cystic lesions of the pancreas.
International journal of cancer. Journal international du cancer 1997;74(3):286-90.
1997: J Thompson; M Seitz; Eric Chastre; Margarethe Ditter; C Aldrian; Christian Gespach; Wolfgang Zimmermann
Down-regulation of carcinoembryonic antigen family member 2 expression is an early event in colorectal tumorigenesis.
Cancer research 1997;57(9):1776-84.
1997: S Djelloul; Marie-Elisabeth Forgue-Lafitte; Brigitte Hermelin; Marc Mareel; Erik Bruyneel; A Baldi; Antonio Giordano; Eric Chastre; Christian Gespach
Enterocyte differentiation is compatible with SV40 large T expression and loss of p53 function in human colonic Caco-2 cells. Status of the pRb1 and pRb2 tumor suppressor gene products.
FEBS letters 1997;406(3):234-42.
1997: Axelle Cadoret; France Bertrand; S Baron-Delage; Peggy Lévy; G Courtois; Christian Gespach; Jacqueline Capeau; G Cherqui
Down-regulation of NF-kappaB activity and NF-kappaB p65 subunit expression by ras and polyoma middle T oncogenes in human colonic Caco-2 cells.
Oncogene 1997;14(13):1589-600.
1997: B Z Vider; Amazia Zimber; D Hirsch; Dov Estlein; Eric Chastre; S Prevot; Christian Gespach; Abraham Yaniv; Arnona Gazit
Human colorectal carcinogenesis is associated with deregulation of homeobox gene expression.
Biochemical and biophysical research communications 1997;232(3):742-8.
1997: Peggy Lévy; A Munier; S Baron-Delage; Eric Chastre; Christian Gespach; Jacqueline Capeau; G Cherqui
[Oncogenic activation of p21ras or pp60c-src in human colonic Caco-2 cells induces post-translation alterations of syndecan-1].
Bulletin du cancer 1997;84(3):235-7.
1997: Azeddine Atfi; S Djelloul; Eric Chastre; R Davis; Christian Gespach
Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor beta-mediated signaling.
The Journal of biological chemistry 1997;272(3):1429-32.
1997: S Empereur; S Djelloul; Yolande Di Gioia; Erik Bruyneel; Marc Mareel; Jolanda van Hengel; Frans van Roy; P Comoglio; S Courtneidge; C Paraskeva; Eric Chastre; Christian Gespach
Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: cooperation between src and HGF/Met in invasion.
British journal of cancer 1997;75(2):241-50.
1996: S E Davenport; Martine Mergey; G Cherqui; Richard C Boucher; Christian Gespach; Sherif E Gabriel
Deregulated expression and function of CFTR and Cl- secretion after activation of the Ras and Src/PyMT pathways in Caco-2 cells.
Biochemical and biophysical research communications 1996;229(2):663-72.
1996: Marie-Elisabeth Forgue-Lafitte; A M Coudray; J P Aubert; Christian Gespach; Jacques Bara
Devazepide (L-364718) inhibits growth and increases expression of tumor markers in HT29-S-B6 cells.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1996;319(12):1133-8.
1996: Eric Raymond; S Djelloul; C Buquet-Fagot; Jan Mester; Christian Gespach
Synergy between the non-classical thymidylate synthase inhibitor AG337 (Thymitaq) and cisplatin in human colon and ovarian cancer cells.
Anti-cancer drugs 1996;7(7):752-7.
1996: P Levy; Annie Munier; S Baron-Delage; Y Di Gioia; Christian Gespach; Jacqueline Capeau; G Cherqui
Syndecan-1 alterations during the tumorigenic progression of human colonic Caco-2 cells induced by human Ha-ras or polyoma middle T oncogenes.
British journal of cancer 1996;74(3):423-31.
1996: Christophe Louvet; S Djelloul; Marie-Elisabeth Forgue-Lafitte; Jan Mester; A Zimber; Christian Gespach
Antiproliferative effects of the arotinoid Ro 40-8757 in human gastrointestinal and pancreatic cancer cell lines: combinations with 5-fluorouracil and interferon-alpha.
British journal of cancer 1996;74(3):394-9.
1996: Louis Buscail; Nathalie Saint-Laurent; Eric Chastre; JC Vaillant; Christian Gespach; G Capella; H Kalthoff; F Lluis; Nicole Vaysse; Christiane Susini
Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer.
Cancer research 1996;56(8):1823-7.
1996: S Baron-Delage; Lahcen Mahraoui; Axelle Cadoret; D Veissiere; Jean-Louis Taillemite; Eric Chastre; Christian Gespach; Alain Zweibaum; Jacqueline Capeau; Edith Brot-Laroche; G Cherqui
Deregulation of hexose transporter expression in Caco-2 cells by ras and polyoma middle T oncogenes.
The American journal of physiology 1996;270(2 Pt 1):G314-23.
1996: B Z Vider; A Zimber; Eric Chastre; S Prevot; Christian Gespach; Dov Estlein; Y Wolloch; S R Tronick; Arnona Gazit; Abraham Yaniv
Evidence for the involvement of the Wnt 2 gene in human colorectal cancer.
Oncogene 1996;12(1):153-8.
1995: M Nagano; Eric Chastre; A Choquet; J Bara; Christian Gespach; Paul A Kelly
Expression of prolactin and growth hormone receptor genes and their isoforms in the gastrointestinal tract.
The American journal of physiology 1995;268(3 Pt 1):G431-42.
1995: Henri Porte; Eric Chastre; S Prevot; B Nordlinger; S Empereur; P Basset; P Chambon; Christian Gespach
Neoplastic progression of human colorectal cancer is associated with overexpression of the stromelysin-3 and BM-40/SPARC genes.
International journal of cancer. Journal international du cancer 1995;64(1):70-5.
1994: A Zimber; A Chedeville; Christian Gespach; J P Abita
Inhibition of proliferation and induction of monocytic differentiation on HL60 human promyelocytic leukemia cells treated with bile acids in vitro.
International journal of cancer. Journal international du cancer 1994;59(1):71-7.
1994: S Baron-Delage; V Barbu; France Bertrand; Eric Chastre; Peggy Lévy; Christian Gespach; Jacqueline Capeau; G Cherqui
[Oncogenic activation of p21(ras) and pp60(c-src) in human colonic Caco-2 cells decreases insulin receptor function and expression through protein kinase C-dependent and independent pathways].
Bulletin du cancer 1994;81(10):882-5.
1994: Christophe Louvet; S Empereur; D Fagot; E Forgue-Lafitte; Eric Chastre; A Zimber; Jan Mester; Christian Gespach
The arotinoid Ro 40-8757 has antiproliferative effects in drug-resistant human colon and breast cancer cell lines in vitro.
Cancer letters 1994;85(1):83-6.
1994: L Mirossay; Eric Chastre; J Callebert; J M Launay; B Housset; A Zimber; J P Abita; Christian Gespach
Histamine H2 receptors and histidine decarboxylase in normal and leukemic human monocytes and macrophages.
The American journal of physiology 1994;267(2 Pt 2):R602-11.
1994: S Baron-Delage; Jacqueline Capeau; V Barbu; Eric Chastre; P Levy; Christian Gespach; G Cherqui
Reduced insulin receptor expression and function in human colonic Caco-2 cells by ras and polyoma middle T oncogenes.
The Journal of biological chemistry 1994;269(28):18686-93.
1993: V Le Meuth; V Philouze-Rome; I Le Huerou-Luron; M Formal; Nicole Vaysse; Christian Gespach; Paul Guilloteau; Daniel Fourmy
Differential expression of A- and B-subtypes of cholecystokinin/gastrin receptors in the developing calf pancreas.
Endocrinology 1993;133(3):1182-91.
1993: S Delage; Eric Chastre; S Empereur; D Wicek; D Veissiére; Jacqueline Capeau; Christian Gespach; G Cherqui
Increased protein kinase C alpha expression in human colonic Caco-2 cells after insertion of human Ha-ras or polyoma virus middle T oncogenes.
Cancer research 1993;53(12):2762-70.
1993: A Chedeville; L Mirossay; Eric Chastre; I Hurbain-Kosmath; M Lopez; Christian Gespach
Interaction of VIP, PACAP and related peptides in normal and leukemic human monocytes and macrophages.
FEBS letters 1993;319(1-2):171-6.
1993: M Lemnaouar; Eric Chastre; Annick Paul; Martine Mergey; D Veissière; G Cherqui; Pascal Barbry; Brigitte Simon-Bouy; Pascale Fanen; Christian Gespach
Oncogene-mediated propagation of tracheal epithelial cells from two cystic fibrosis fetuses with different mutations. Characterization of CFT-1 and CFT-2 cells in culture.
European journal of clinical investigation 1993;23(3):151-60.
1992: L Mirossay; Y Di Gioia; Eric Chastre; Shahin Emami; Christian Gespach
Pharmacological control of gastric acid secretion: molecular and cellular aspects.
Bioscience reports 1992;12(5):319-68.
1992: P Berthon; L Mirossay; S Ito; F Calvo; Christian Gespach
Functional expression of VIP receptors in normal, immortalized and transformed mammary epithelial cells.
Life sciences 1992;50(11):791-8.
1991: Eric Chastre; Y Di Gioia; Pascal Barbry; Brigitte Simon-Bouy; Etienne Mornet; Pascale Fanen; G Champigny; Shahin Emami; Christian Gespach
Functional insertion of the SV40 large T oncogene in cystic fibrosis intestinal epithelium. Characterization of CFI-3 cells.
The Journal of biological chemistry 1991;266(31):21239-46.
1991: V Le Meuth; N Farjaudon; W Bawab; Eric Chastre; GE Rosselin; Paul Guilloteau; Christian Gespach
Characterization of binding sites for VIP-related peptides and activation of adenylate cyclase in developing pancreas.
The American journal of physiology 1991;260(2 Pt 1):G265-74.
1991: W Bawab; Eric Chastre; Christian Gespach
Functional and structural characterization of the secretin receptors in rat gastric glands: desensitization and glycoprotein nature.
Bioscience reports 1991;11(1):33-42.
1990: Shahin Emami; Eric Chastre; S Nizard; Y Di Gioia; V Barbu; Jean-Louis Taillemite; S Ito; Christian Gespach
Immortalization and neoplastic transformation of fetal rat intestinal epithelial cells: morphological and cytogenetic analysis, (proto)oncogene expression and effect of gamma-interferon on cell growth.
Digestion 1990;46 Suppl 2():74-91.
1990: Christian Gespach; Shahin Emami; Y Di Gioia; Eric Chastre
[Gastric acid secretion and histamine H2 receptor antagonists].
Gastroentérologie clinique et biologique 1990;14(12):982-94.
1989: Eric Chastre; W Bawab; Christophe Faure; Shahin Emami; F Muller; A Boué; Christian Gespach
Vasoactive intestinal peptide and its receptors in fetuses with cystic fibrosis.
The American journal of physiology 1989;257(4 Pt 1):G561-9.
1989: Shahin Emami; L Mir; Christian Gespach; GE Rosselin
Transfection of fetal rat intestinal epithelial cells by viral oncogenes: establishment and characterization of the E1A-immortalized SLC-11 cell line.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3194-8.
1989: Christian Gespach; A Hansen; J Holst
Differential regulation of membrane receptors sensitive to histamine (H2-type), isoproterenol (beta 2-type) and glucagon-like peptides by the somatostatin analogue Sandostatin in rat gastric glands.
Agents and actions 1989;27(1-2):169-72.
1989: Christian Gespach; D Fagot; Shahin Emami
Pharmacological control of the human gastric histamine H2 receptor by famotidine: comparison with H1, H2 and H3 receptor agonists and antagonists.
European journal of clinical investigation 1989;19(1):1-10.
1989: Eric Chastre; Shahin Emami; Christian Gespach
Expression of membrane receptors and (proto)oncogenes during the ontogenic development and neoplastic transformation of the intestinal mucosa.
Life sciences 1989;44(23):1721-42.
1988: Christian Gespach; W Bawab; P de Cremoux; F Calvo
Pharmacology, molecular identification and functional characteristics of vasoactive intestinal peptide receptors in human breast cancer cells.
Cancer research 1988;48(18):5079-83.
1988: A B Hansen; Christian Gespach; GE Rosselin; J J Holst
Effect of truncated glucagon-like peptide 1 on cAMP in rat gastric glands and HGT-1 human gastric cancer cells.
FEBS letters 1988;236(1):119-22.
1988: Christian Gespach; Shahin Emami; Eric Chastre
Membrane receptors in the gastrointestinal tract.
Bioscience reports 1988;8(3):199-232.
1988: D Fagot; Shahin Emami; Eric Chastre; W Bawab; Christian Gespach
Pharmacological control of the histamine H2 receptor-adenylate cyclase system by famotidine and ranitidine in normal and cancerous human gastric epithelia.
Agents and actions 1988;23(3-4):293-6.
1988: Shahin Emami; L Mir; P Chanut; Eric Chastre; F Chatelet; Jean Feunteun; Christian Gespach
Expression of histamine and vasoactive intestinal peptide (VIP) receptors in immortalized rat fetal intestinal cells.
Agents and actions 1988;23(3-4):276-9.
1988: Christian Gespach; W Bawab; Eric Chastre; Shahin Emami; N Yanaihara; GE Rosselin
Pharmacology and molecular identification of vasoactive intestinal peptide (VIP) receptors in normal and cancerous gastric mucosa in man.
Biochemical and biophysical research communications 1988;151(2):939-47.
1988: W Bawab; Christian Gespach; J C Marie; Eric Chastre; GE Rosselin
Pharmacology and molecular identification of secretin receptors in rat gastric glands.
Life sciences 1988;42(7):791-8.
1987: Eric Chastre; Shahin Emami; GE Rosselin; Christian Gespach
Ontogenic development of vasoactive intestinal peptide receptors in rat intestinal cells and liver.
Endocrinology 1987;121(6):2211-21.
1987: Christian Gespach; Shahin Emami; Eric Chastre; J M Launay; GE Rosselin
Up- and down-regulation of membrane receptors as possible mechanisms related to the antiulcer actions of milk in rat gastric mucosa.
Bioscience reports 1987;7(2):135-42.
1986: C Boissard; J C Marie; G Hejblum; Christian Gespach; GE Rosselin
Vasoactive intestinal peptide receptor regulation and reversible desensitization in human colonic carcinoma cells in culture.
Cancer research 1986;46(9):4406-13.
1984: C Boissard; G Hejblum; J C Marie; Christian Gespach; GE Rosselin
[Desensitization to VIP by down regulation of its peptide receptors in transformed HT-29 cells of human colonic epithelium in culture].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1984;299(19):795-8.