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Jeroen Geurts

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Hanneke E Hulst; Chris H Polman; Petra J W Pouwels; Martijn D Steenwijk; Bernard M J Uitdehaag; Adriaan Versteeg; Hugo Vrenken; Jeroen J G Geurts; Frederik Barkhof
Cognitive impairment in MS: impact of white matter integrity, gray matter volume, and lesions.
Wolter L de Graaf; Jeroen J G Geurts; Iris D Kilsdonk; Alexandra Lopez-Soriano; Peter R Luijten; Chris H Polman; Petra J W Pouwels; Fredy Visser; Frederik Barkhof; Jonas A Castelijns; Jaco J M Zwanenburg; Mike P Wattjes
Clinical application of multi-contrast 7-T MR imaging in multiple sclerosis: increased lesion detection compared to 3 T confined to grey matter.
Roel Klaver; Geert J Schenk; Helga E de Vries; Jeroen J G Geurts
Grey matter damage in multiple sclerosis: a pathology perspective.

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All Publications

2013: Hanneke E Hulst; Chris H Polman; Petra J W Pouwels; Martijn D Steenwijk; Bernard M J Uitdehaag; Adriaan Versteeg; Hugo Vrenken; Jeroen J G Geurts; Frederik Barkhof
Cognitive impairment in MS: impact of white matter integrity, gray matter volume, and lesions.
Neurology 2013;80(11):1025-32.
2013: Wolter L de Graaf; Jeroen J G Geurts; Iris D Kilsdonk; Alexandra Lopez-Soriano; Peter R Luijten; Chris H Polman; Petra J W Pouwels; Fredy Visser; Frederik Barkhof; Jonas A Castelijns; Jaco J M Zwanenburg; Mike P Wattjes
Clinical application of multi-contrast 7-T MR imaging in multiple sclerosis: increased lesion detection compared to 3 T confined to grey matter.
European radiology 2013;23(2):528-40.
2013: Roel Klaver; Geert J Schenk; Helga E de Vries; Jeroen J G Geurts
Grey matter damage in multiple sclerosis: a pathology perspective.
Prion 2013;7(1):66-75.
2013: Becky Inkster; Ludwig Kappos; Paul M Matthews; Giovanni Montana; Chris H Polman; Ernst-Wilhelm Radue; Eva M M Strijbis; Bernard M J Uitdehaag; Maria Vounou; Frederik Barkhof; Jeroen J G Geurts
Histone deacetylase gene variants predict brain volume changes in multiple sclerosis.
Neurobiology of aging 2013;34(1):238-47.
2013: Menno M Schoonheim; Marieke L van der Meer; Hugo Vrenken; Frederik Barkhof; Linda Douw; Jeroen J G Geurts; Doriana Landi; Chris H Polman; Cornelis J Stam
Functional connectivity changes in multiple sclerosis patients: a graph analytical study of MEG resting state data.
Human brain mapping 2013;34(1):52-61.
2012: Menno M Schoonheim; Hugo Vrenken; Oliver T Wiebenga; Linda Douw; Jeroen J G Geurts; Chris H Polman; Veronica Popescu; Fernanda C Rueda Lopes; Frederik Barkhof
Subcortical atrophy and cognition: sex effects in multiple sclerosis.
Neurology 2012;79(17):1754-61.
2012: Hanneke E Hulst; Chris H Polman; Veronica Popescu; Stefan D Roosendaal; Menno M Schoonheim; Lizanne J S Schweren; Ysbrand D Van der Werf; Leo H Visser; Frederik Barkhof; Jeroen J G Geurts
Functional adaptive changes within the hippocampal memory system of patients with multiple sclerosis.
Human brain mapping 2012;33(10):2268-80.
2012: Evert-Jan Kooi; Eva M M Strijbis; Paul van der Valk; Jeroen J G Geurts
Heterogeneity of cortical lesions in multiple sclerosis: clinical and pathologic implications.
Neurology 2012;79(13):1369-76.
2012: Peter K Stys; Jan van Minnen; Gerald W Zamponi; Jeroen J G Geurts
Will the real multiple sclerosis please stand up?
Nature reviews. Neuroscience 2012;13(7):507-14.
2012: René M Vigeveno; Mike P Wattjes; Oliver T Wiebenga; Jeroen J G Geurts; Frederik Barkhof
Shifting imaging targets in multiple sclerosis: from inflammation to neurodegeneration.
Journal of magnetic resonance imaging : JMRI 2012;36(1):1-19.
2012: Kerstin Bendfeldt; Frederik Barkhof; Achim Gass; Jeroen J G Geurts; Louis Hofstetter; Ludwig Kappos; Pascal Kuster; Nicole Mueller-Lenke; Yvonne Naegelin; Thomas E Nichols; Ernst-Wilhelm Radue; Stefan D Roosendaal; Stefan Traud; Hugo Vrenken; Stefan J Borgwardt
Longitudinal gray matter changes in multiple sclerosis--differential scanner and overall disease-related effects.
Human brain mapping 2012;33(5):1225-45.
2012: Massimo Filippi; Jeroen J G Geurts; Hans Lassmann; Claudia Lucchinetti; David H Miller; Daniel Pelletier; Bogdan F Gh Popescu; Maria A Rocca; Frederik Barkhof; Wolfgang Brück; Jacqueline T Chen; Giancarlo Comi; Nicola de Stefano; Gabriele DeLuca; Bradley J Erickson; Nikos Evangelou; Franz Fazekas
Association between pathological and MRI findings in multiple sclerosis.
Lancet neurology 2012;11(4):349-60.
2012: Martin Hardmeier; Arjan Hillebrand; Chris H Polman; Menno M Schoonheim; Frederik Barkhof; Jeroen J G Geurts; Cornelis J Stam
Cognitive dysfunction in early multiple sclerosis: altered centrality derived from resting-state functional connectivity using magneto-encephalography.
PloS one 2012;7(7):e42087.
2012: Wolter L de Graaf; Jeroen J G Geurts; Peter R Luijten; Chris H Polman; Petra J W Pouwels; Fredy Visser; Mike P Wattjes; Jaco J M Zwanenburg; Frederik Barkhof; Jonas A Castelijns
Lesion detection at seven Tesla in multiple sclerosis using magnetisation prepared 3D-FLAIR and 3D-DIR.
European radiology 2012;22(1):221-31.
2011: Yolanda S Kap; Evert-Jan Kooi; Jon D Laman; Paul W H I Parren; Jan Bauer; Wim K Bleeker; Erwin L A Blezer; Jenny L Craigen; Nikki van Driel; Jeroen J G Geurts; Bert A 't Hart
B-cell depletion attenuates white and gray matter pathology in marmoset experimental autoimmune encephalomyelitis.
Journal of neuropathology and experimental neurology 2011;70(11):992-1005.
2011: Evert-Jan Kooi; Marloes Prins; Anne-Marie Van Dam; Paul Van Der Valk; Jack van Horssen; Eleonora Aronica; Natasha Bajic; Jeroen A M Beliën; Paul T Francis; Wouter H Gerritsen; Jeroen J M Hoozemans; Jeroen J G Geurts
Cholinergic imbalance in the multiple sclerosis hippocampus.
Acta neuropathologica 2011;122(3):313-22.
2011: Declan T Chard; Jeroen J G Geurts
Predicting the development of multiple sclerosis: is gray matter a missing piece of the puzzle?
Neurology 2011;77(3):210-1.
2011: Jeroen J G Geurts; S D Roosendaal; M Calabrese; O Ciccarelli; Federica Agosta; D T Chard; A Gass; E Huerga; B Moraal; D Pareto; M A Rocca; Mike P Wattjes; Tarek A Yousry; B M J Uitdehaag; Frederik Barkhof
Consensus recommendations for MS cortical lesion scoring using double inversion recovery MRI.
Neurology 2011;76(5):418-24.
2011: Johannes M van Noort; Peter J van den Elsen; Jack van Horssen; Jeroen J G Geurts; Paul Van Der Valk; Sandra Amor
Preactive multiple sclerosis lesions offer novel clues for neuroprotective therapeutic strategies.
CNS & neurological disorders drug targets 2011;10(1):68-81.
2011: Alida A Gouw; Alexandra Seewann; Wiesje M van der Flier; Frederik Barkhof; Annemieke M Rozemuller; Philip scheltens; Jeroen J G Geurts
Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations.
Journal of neurology, neurosurgery, and psychiatry 2011;82(2):126-35.
2010: Jeroen J G Geurts; Evert-Jan Kooi; Maarten E Witte; Paul Van Der Valk
Multiple sclerosis as an "inside-out" disease.
Annals of neurology 2010;68(5):767-8; author reply 768.
2010: Jeroen J G Geurts; Hugo Vrenken
Toward understanding cortical lesions in multiple sclerosis.
Neurology 2010;75(14):1224-5.
2010: Maarten E Witte; Jeroen J G Geurts; Helga E de Vries; Paul Van Der Valk; Jack van Horssen
Mitochondrial dysfunction: a potential link between neuroinflammation and neurodegeneration?
Mitochondrion 2010;10(5):411-8.
2010: Birgit Simon; Stephan Schmidt; Carsten Lukas; Jürgen Gieseke; Frank Träber; Dirk L Knol; Winfried A Willinek; Jeroen J G Geurts; Hans H Schild; Frederik Barkhof; Mike P Wattjes
Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla.
European radiology 2010;20(7):1675-83.
2010: Øivind Torkildsen; Christine Stansberg; Solveig M Angelskår; Evert-Jan Kooi; Jeroen J G Geurts; Paul van der Valk; Kjell-Morten Myhr; Vidar M Steen; Lars Bø
Upregulation of immunoglobulin-related genes in cortical sections from multiple sclerosis patients.
Brain pathology (Zurich, Switzerland) 2010;20(4):720-9.
2010: Stefan D Roosendaal; Menno M Schoonheim; Hanneke E Hulst; Ernesto Sanz Arigita; Stephen M Smith; Jeroen J G Geurts; Frederik Barkhof
Resting state networks change in clinically isolated syndrome.
Brain : a journal of neurology 2010;133(Pt 6):1612-21.
2010: Bastiaan Moraal; Ivo J van den Elskamp; Dirk L Knol; Bernard M J Uitdehaag; Jeroen J G Geurts; Hugo Vrenken; Petra J W Pouwels; Ronald A van Schijndel; Dominik S Meier; Charles R G Guttmann; Frederik Barkhof
Long-interval T2-weighted subtraction magnetic resonance imaging: a powerful new outcome measure in multiple sclerosis trials.
Annals of neurology 2010;67(5):667-75.
2010: Menno M Schoonheim; Jeroen J G Geurts; Frederik Barkhof
The limits of functional reorganization in multiple sclerosis.
Neurology 2010;74(16):1246-7.
2010: Bastiaan Moraal; Mike P Wattjes; Jeroen J G Geurts; Dirk L Knol; Ronald A van Schijndel; Petra J W Pouwels; Hugo Vrenken; Frederik Barkhof
Improved detection of active multiple sclerosis lesions: 3D subtraction imaging.
Radiology 2010;255(1):154-63.
2010: Jeroen J G Geurts; Jack van Horssen
The brake on neurodegeneration: Increased mitochondrial metabolism in the injured MS spinal cord.
Neurology 2010;74(9):710-1.
2009: Madeleine H Sombekke; Carsten Lukas; J B A Crusius; Diego Tejedor; Joep Killestein; David Arteta; Antonio Martínez; Bernard M J Uitdehaag; Dirk L Knol; Amado Salvador Peña; Jeroen J G Geurts; Philip L De Jager; Frederik Barkhof; Hugo Vrenken; Chris H Polman
HLA-DRB1*1501 and spinal cord magnetic resonance imaging lesions in multiple sclerosis.
Archives of neurology 2009;66(12):1531-6.
2009: Mike P Wattjes; Wouter J P Henneman; Wiesje M van der Flier; Oscar de Vries; Frank Träber; Jeroen J G Geurts; Philip scheltens; Hugo Vrenken; Frederik Barkhof
Diagnostic imaging of patients in a memory clinic: comparison of MR imaging and 64-detector row CT.
Radiology 2009;253(1):174-83.
2009: Maarten E Witte; Lars Bø; Richard J Rodenburg; Jeroen A M Belien; Rene Musters; Thierry Hazes; Liesbeth T Wintjes; Jan A Smeitink; Jeroen J G Geurts; Helga E de Vries; Paul Van Der Valk; Jack van Horssen
Enhanced number and activity of mitochondria in multiple sclerosis lesions.
The Journal of pathology 2009;219(2):193-204.
2009: Evert-Jan Kooi; Jeroen J G Geurts; Jack van Horssen; Lars Bø; Paul van der Valk
Meningeal inflammation is not associated with cortical demyelination in chronic multiple sclerosis.
Journal of neuropathology and experimental neurology 2009;68(9):1021-8.
2009: Jeroen J G Geurts; Peter K Stys; A Minagar; Sandra Amor; R Zivadinov
Gray matter pathology in (chronic) MS: modern views on an early observation.
Journal of the neurological sciences 2009;282(1-2):12-20.
2009: Jeroen J G Geurts
Milestone: neurology's growth factor: 100 years of Rita Levi-Montalcini.
Nature reviews. Neurology 2009;5(7):355-6.
2009: E-J Kooi; Jack van Horssen; M E Witte; Sandra Amor; L Bø; Christine D Dijkstra; Paul Van Der Valk; Jeroen J G Geurts
Abundant extracellular myelin in the meninges of patients with multiple sclerosis.
Neuropathology and applied neurobiology 2009;35(3):283-95.
2009: A Seewann; E-J Kooi; S D Roosendaal; Frederik Barkhof; P van der Valk; Jeroen J G Geurts
Translating pathology in multiple sclerosis: the combination of postmortem imaging, histopathology and clinical findings.
Acta neurologica Scandinavica 2009;119(6):349-55.
2009: Alexandra Seewann; Hugo Vrenken; Paul Van Der Valk; Erwin L A Blezer; Dirk L Knol; Jonas A Castelijns; Chris H Polman; Petra J W Pouwels; Frederik Barkhof; Jeroen J G Geurts
Diffusely abnormal white matter in chronic multiple sclerosis: imaging and histopathologic analysis.
Archives of neurology 2009;66(5):601-9.
2009: Machteld M Vellinga; Hugo Vrenken; Hanneke E Hulst; Chris H Polman; Bernard M J Uitdehaag; Petra J W Pouwels; Frederik Barkhof; Jeroen J G Geurts
Use of ultrasmall superparamagnetic particles of iron oxide (USPIO)-enhanced MRI to demonstrate diffuse inflammation in the normal-appearing white matter (NAWM) of multiple sclerosis (MS) patients: an exploratory study.
Journal of magnetic resonance imaging : JMRI 2009;29(4):774-9.
2009: S D Roosendaal; Jeroen J G Geurts; Hugo Vrenken; H E Hulst; Keith S Cover; Jonas A Castelijns; Petra J W Pouwels; Frederik Barkhof
Regional DTI differences in multiple sclerosis patients.
NeuroImage 2009;44(4):1397-403.
2009: Richard Daniëls; Jeroen J G Geurts; Joost C J Bot; Wouter J Schonewille; Bob W van Oosten
Steroid-responsive edema in CAA-related inflammation.
Journal of neurology 2009;256(2):285-6.
2009: Bastiaan Moraal; Dominik Meier; Peter A Poppe; Jeroen J G Geurts; Hugo Vrenken; William M A Jonker; Dirk L Knol; Ronald A van Schijndel; Petra J W Pouwels; Christoph Pohl; Lars Bauer; Rupert Sandbrink; Charles R G Guttmann; Frederik Barkhof
Subtraction MR images in a multiple sclerosis multicenter clinical trial setting.
Radiology 2009;250(2):506-14.
2008: Karin Boer; Dirk Troost; Floor Jansen; Mark Nellist; Ans M W van den Ouweland; Jeroen J G Geurts; Wim G M Spliet; Peter B Crino; Eleonora Aronica
Clinicopathological and immunohistochemical findings in an autopsy case of tuberous sclerosis complex.
Neuropathology : official journal of the Japanese Society of Neuropathology 2008;28(6):577-90.
2008: Bastiaan Moraal; Stefan D Roosendaal; Petra J W Pouwels; Hugo Vrenken; Ronald A van Schijndel; Dominik Meier; Charles R G Guttmann; Jeroen J G Geurts; Frederik Barkhof
Multi-contrast, isotropic, single-slab 3D MR imaging in multiple sclerosis.
European radiology 2008;18(10):2311-20.
2008: Jeroen J G Geurts
Is progressive multiple sclerosis a gray matter disease?
Annals of neurology 2008;64(3):230-2.
2008: Stefan D Roosendaal; Bastiaan Moraal; Hugo Vrenken; Jonas A Castelijns; Petra J W Pouwels; Frederik Barkhof; Jeroen J G Geurts
In vivo MR imaging of hippocampal lesions in multiple sclerosis.
Journal of magnetic resonance imaging : JMRI 2008;27(4):726-31.
2008: Machteld M Vellinga; Raoul D Oude Engberink; Alexandra Seewann; Petra J W Pouwels; Mike P Wattjes; Susanne M A van der Pol; Christiane Pering; Chris H Polman; Helga E de Vries; Jeroen J G Geurts; Frederik Barkhof
Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement.
Brain : a journal of neurology 2008;131(Pt 3):800-7.
2008: Jeroen J G Geurts; Erwin L A Blezer; Hugo Vrenken; Annette van der Toorn; Jonas A Castelijns; Chris H Polman; Petra J W Pouwels; Lars Bö; Frederik Barkhof
Does high-field MR imaging improve cortical lesion detection in multiple sclerosis?
Journal of neurology 2008;255(2):183-91.
2007: Jeroen J G Geurts; Lars Bö; Stefan D Roosendaal; Thierry Hazes; Richard Daniëls; Frederik Barkhof; Menno P Witter; Inge Huitinga; Paul Van Der Valk
Extensive hippocampal demyelination in multiple sclerosis.
Journal of neuropathology and experimental neurology 2007;66(9):819-27.
2007: Hugo Vrenken; Petra J W Pouwels; Stefan Ropele; Dirk L Knol; Jeroen J G Geurts; Chris H Polman; Frederik Barkhof; Jonas A Castelijns
Magnetization transfer ratio measurement in multiple sclerosis normal-appearing brain tissue: limited differences with controls but relationships with clinical and MR measures of disease.
Multiple sclerosis (Houndmills, Basingstoke, England) 2007;13(6):708-16.
2007: Nynke F Kalkers; Rob L M Strijers; M M S Jasperse; V Neacsu; Jeroen J G Geurts; Frederik Barkhof; Chris H Polman; Cornelis Stam
Motor evoked potential: a reliable and objective measure to document the functional consequences of multiple sclerosis? Relation to disability and MRI.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2007;118(6):1332-40.
2007: Hugo Vrenken; Jeroen J G Geurts
Gray and normal-appearing white matter in multiple sclerosis: an MRI perspective.
Expert review of neurotherapeutics 2007;7(3):271-9.
2007: Lars Bö; Jeroen J G Geurts; Paul Van Der Valk; Chris H Polman; Frederik Barkhof
Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis.
Archives of neurology 2007;64(1):76-80.
2006: Hugo Vrenken; Jeroen J G Geurts; Dirk L Knol; Chris H Polman; Jonas A Castelijns; Petra J W Pouwels; Frederik Barkhof
Normal-appearing white matter changes vary with distance to lesions in multiple sclerosis.
AJNR. American journal of neuroradiology 2006;27(9):2005-11.
2006: Hugo Vrenken; Jeroen J G Geurts; Dirk L Knol; L Noor van Dijk; Vincenzo Dattola; jasperse bas; Ronald A van Schijndel; Chris H Polman; Jonas A Castelijns; Frederik Barkhof; Petra J W Pouwels
Whole-brain T1 mapping in multiple sclerosis: global changes of normal-appearing gray and white matter.
Radiology 2006;240(3):811-20.
2006: Hugo Vrenken; Petra J W Pouwels; Jeroen J G Geurts; Dirk L Knol; Chris H Polman; Frederik Barkhof; Jonas A Castelijns
Altered diffusion tensor in multiple sclerosis normal-appearing brain tissue: cortical diffusion changes seem related to clinical deterioration.
Journal of magnetic resonance imaging : JMRI 2006;23(5):628-36.
2006: Jeroen J G Geurts; Ilona E W Reuling; Hugo Vrenken; Bernard Uitdehaag; Chris H Polman; Jonas A Castelijns; Frederik Barkhof; Petra J W Pouwels
MR spectroscopic evidence for thalamic and hippocampal, but not cortical, damage in multiple sclerosis.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;55(3):478-83.
2006: Keith S Cover; Hugo Vrenken; Jeroen J G Geurts; Bob W van Oosten; Brechtje Jelles; Chris H Polman; Cornelis Stam; Bob W van Dijk
Multiple sclerosis patients show a highly significant decrease in alpha band interhemispheric synchronization measured using MEG.
NeuroImage 2006;29(3):783-8.
2006: Lars Bö; Jeroen J G Geurts; Sverre Mörk; Paul Van Der Valk
Grey matter pathology in multiple sclerosis.
Acta neurologica Scandinavica. Supplementum 2006;183():48-50.
2005: Catharina M P Vos; Jeroen J G Geurts; Lisette Montagne; Elise S van Haastert; Lars Bö; Paul Van Der Valk; Frederik Barkhof; Helga E de Vries
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis.
Neurobiology of disease 2005;20(3):953-60.
2005: Jeroen J G Geurts; Petra J W Pouwels; Bernard Uitdehaag; Chris H Polman; Frederik Barkhof; Jonas A Castelijns
Intracortical lesions in multiple sclerosis: improved detection with 3D double inversion-recovery MR imaging.
Radiology 2005;236(1):254-60.
2005: Jeroen J G Geurts; Lars Bö; Petra J W Pouwels; Jonas A Castelijns; Chris H Polman; Frederik Barkhof
Cortical lesions in multiple sclerosis: combined postmortem MR imaging and histopathology.
AJNR. American journal of neuroradiology 2005;26(3):572-7.
2005: Jeroen J G Geurts; G Wolswijk; Lars Bö; Sandra Redeker; Marja Ramkema; Dirk Troost; Eleonora Aronica
Expression patterns of Group III metabotropic glutamate receptors mGluR4 and mGluR8 in multiple sclerosis lesions.
Journal of neuroimmunology 2005;158(1-2):182-90.
2004: Jeroen J G Geurts; Frederik Barkhof; Jonas A Castelijns; Bernard Uitdehaag; Chris H Polman; Petra J W Pouwels
Quantitative 1H-MRS of healthy human cortex, hippocampus, and thalamus: metabolite concentrations, quantification precision, and reproducibility.
Journal of magnetic resonance imaging : JMRI 2004;20(3):366-71.
2004: Lars Bö; Jeroen J G Geurts; Rivka Ravid; Frederik Barkhof
Magnetic resonance imaging as a tool to examine the neuropathology of multiple sclerosis.
Neuropathology and applied neurobiology 2004;30(2):106-17.
2003: Frederik Barkhof; Wolfgang Bruck; Christianne J M De Groot; Elisabeth Bergers; Sandra Hulshof; Jeroen J G Geurts; Chris H Polman; Paul Van Der Valk
Remyelinated lesions in multiple sclerosis: magnetic resonance image appearance.
Archives of neurology 2003;60(8):1073-81.
2003: Jeroen J G Geurts; G Wolswijk; Lars Bö; Paul Van Der Valk; Chris H Polman; Dirk Troost; Eleonora Aronica
Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis.
Brain : a journal of neurology 2003;126(Pt 8):1755-66.