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Daniel Gewirth

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Publications

TOP 3
Robert M Immormino; Louis E Metzger; Patrick N Reardon; D Eric Dollins; Brian S J Blagg; Daniel T Gewirth
Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
D Eric Dollins; Joshua J Warren; Robert M Immormino; Daniel T Gewirth
Structures of GRP94-nucleotide complexes reveal mechanistic differences between the hsp90 chaperones.
Robert M Immormino; Yanlong Kang; Gabriela Chiosis; Daniel T Gewirth
Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors.

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All Publications

2009: Robert M Immormino; Louis E Metzger; Patrick N Reardon; D Eric Dollins; Brian S J Blagg; Daniel T Gewirth
Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
Journal of molecular biology 2009;388(5):1033-42.
2007: D Eric Dollins; Joshua J Warren; Robert M Immormino; Daniel T Gewirth
Structures of GRP94-nucleotide complexes reveal mechanistic differences between the hsp90 chaperones.
Molecular cell 2007;28(1):41-56.
2006: Robert M Immormino; Yanlong Kang; Gabriela Chiosis; Daniel T Gewirth
Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors.
Journal of medicinal chemistry 2006;49(16):4953-60.
2006: Allison H Williams; Robert M Immormino; Daniel T Gewirth; Christian R H Raetz
Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(29):10877-82.
2006: Huazhong He; Danuta Zatorska; Joungnam Kim; Julia Aguirre; Laura Llauger; Yuhong She; Nian Wu; Robert M Immormino; Daniel T Gewirth; Gabriela Chiosis
Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.
Journal of medicinal chemistry 2006;49(1):381-90.
2005: D Eric Dollins; Robert M Immormino; Daniel T Gewirth
Structure of unliganded GRP94, the endoplasmic reticulum Hsp90. Basis for nucleotide-induced conformational change.
The Journal of biological chemistry 2005;280(34):30438-47.
2005: Paul L Shaffer; Donald P McDonnell; Daniel T Gewirth
Characterization of transcriptional activation and DNA-binding functions in the hinge region of the vitamin D receptor.
Biochemistry 2005;44(7):2678-85.
2004: Robert M Immormino; D Eric Dollins; Paul L Shaffer; Karen L Soldano; Melissa A Walker; Daniel T Gewirth
Ligand-induced conformational shift in the N-terminal domain of GRP94, an Hsp90 chaperone.
The Journal of biological chemistry 2004;279(44):46162-71.
2004: Paul L Shaffer; Daniel T Gewirth
Structural analysis of RXR-VDR interactions on DR3 DNA.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):215-9.
2004: Paul L Shaffer; Arif Jivan; D Eric Dollins; Frank Claessens; Daniel T Gewirth
Structural basis of androgen receptor binding to selective androgen response elements.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4758-63.
2004: Frank Claessens; Daniel T Gewirth
DNA recognition by nuclear receptors.
Essays in biochemistry 2004;40():59-72.
2004: Paul L Shaffer; Daniel T Gewirth
Vitamin D receptor-DNA interactions.
Vitamins and hormones 2004;68():257-73.
2003: Karen L Soldano; Arif Jivan; Christopher V Nicchitta; Daniel T Gewirth
Structure of the N-terminal domain of GRP94. Basis for ligand specificity and regulation.
The Journal of biological chemistry 2003;278(48):48330-8.
2002: Paul L Shaffer; Daniel T Gewirth
Structural basis of VDR-DNA interactions on direct repeat response elements.
The EMBO journal 2002;21(9):2242-52.
2001: S M Wang ; G J Kim ; Daniel T Gewirth
Structural studies of a yeast quaternary transcription-initiation complex.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 3):441-4.