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Jeanne Geyer

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Chemicals & Drugs

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Jeanne A Geyer; Susan Keenan; Cassandra L Woodard; Philip A Thompson; Lucia Gerena; Daniel A Nichols; Clare E Gutteridge; Norman C Waters
Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones.
Cassandra L Woodard; Susan Keenan; Lucia Gerena; WILLIAM J WELSH; Jeanne A Geyer; Norman C Waters
Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk.
Yueqin Chen; Dayadevi Jirage; Diana Caridha; April K Kathcart; Edison A Cortes; Richard A Dennull; Jeanne A Geyer; Sean T Prigge; Norman C Waters
Identification of an effector protein and gain-of-function mutants that activate Pfmrk, a malarial cyclin-dependent protein kinase.

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All Publications

2009: Jeanne A Geyer; Susan Keenan; Cassandra L Woodard; Philip A Thompson; Lucia Gerena; Daniel A Nichols; Clare E Gutteridge; Norman C Waters
Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones.
Bioorganic & medicinal chemistry letters 2009;19(7):1982-5.
2007: Cassandra L Woodard; Susan Keenan; Lucia Gerena; WILLIAM J WELSH; Jeanne A Geyer; Norman C Waters
Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk.
Bioorganic & medicinal chemistry letters 2007;17(17):4961-6.
2006: Yueqin Chen; Dayadevi Jirage; Diana Caridha; April K Kathcart; Edison A Cortes; Richard A Dennull; Jeanne A Geyer; Sean T Prigge; Norman C Waters
Identification of an effector protein and gain-of-function mutants that activate Pfmrk, a malarial cyclin-dependent protein kinase.
Molecular and biochemical parasitology 2006;149(1):48-57.
2005: Jeanne A Geyer; Sean T Prigge; Norman C Waters
Targeting malaria with specific CDK inhibitors.
Biochimica et biophysica acta 2005;1754(1-2):160-70.
2005: Susan Keenan; Jeanne A Geyer; WILLIAM J WELSH; Sean T Prigge; Norman C Waters
Rational inhibitor design and iterative screening in the identification of selective plasmodial cyclin dependent kinase inhibitors.
Combinatorial chemistry & high throughput screening 2005;8(1):27-38.
2004: Apurba K Bhattacharjee; Jeanne A Geyer; Cassandra L Woodard; April K Kathcart; Daniel A Nichols; Sean T Prigge; Zhiyu Li; Bryan T Mott; Norman C Waters
A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors.
Journal of medicinal chemistry 2004;47(22):5418-26.
2003: Cassandra L Woodard; Zhiyu Li; April K Kathcart; James Terrell; Lucia Gerena; Miriam Lopez-Sanchez; Dennis E Kyle; Apurba K Bhattacharjee; Daniel A Nichols; William Ellis; Sean T Prigge; Jeanne A Geyer; Norman C Waters
Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.
Journal of medicinal chemistry 2003;46(18):3877-82.
2003: Norman C Waters; Jeanne A Geyer
Cyclin-dependent protein kinases as therapeutic drug targets for antimalarial drug development.
Expert opinion on therapeutic targets 2003;7(1):7-17.
2001: Zhiyu Li; Karine G Le Roch; Jeanne A Geyer; Cassandra L Woodard; Sean T Prigge; James Koh; Christian Doerig; Norman C Waters
Influence of human p16(INK4) and p21(CIP1) on the in vitro activity of recombinant Plasmodium falciparum cyclin-dependent protein kinases.
Biochemical and biophysical research communications 2001;288(5):1207-11.