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Ameen Ghannam

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Bin Ye; Shawn Bauer; Brad Buckman; Ameen Ghannam; Brian D Griedel; Seock-Kyu Khim; Wheeseong Lee; Karna L Sacchi; Kenneth J Shaw; Amy Liang; Qingyu Wu; Zuchun Zhao
Synthesis and biological evaluation of menthol-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1).
Brad Buckman; Ameen Ghannam; Li Angela; Meina Liang; Raju Mohan; Howard P Ng
Automated parallel solid-phase synthesis of non-peptide CCR1 receptor antagonists.
Richard Horuk; S Shurey; Howard P Ng; K May; John G Bauman; Imadul Islam; Ameen Ghannam; Brad Buckman; Guo-Ping Wei; Wei Xu; Meina Liang; Mary Rosser; Laura Dunning; Joseph Hesselgesser; RM Snider; Michael M Morrissey; H Daniel Perez; C Green
CCR1-specific non-peptide antagonist: efficacy in a rabbit allograft rejection model.

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All Publications

2003: Bin Ye; Shawn Bauer; Brad Buckman; Ameen Ghannam; Brian D Griedel; Seock-Kyu Khim; Wheeseong Lee; Karna L Sacchi; Kenneth J Shaw; Amy Liang; Qingyu Wu; Zuchun Zhao
Synthesis and biological evaluation of menthol-based derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1).
Bioorganic & medicinal chemistry letters 2003;13(19):3361-5.
2002: Brad Buckman; Ameen Ghannam; Li Angela; Meina Liang; Raju Mohan; Howard P Ng
Automated parallel solid-phase synthesis of non-peptide CCR1 receptor antagonists.
Combinatorial chemistry & high throughput screening 2002;5(3):249-51.
2001: Richard Horuk; S Shurey; Howard P Ng; K May; John G Bauman; Imadul Islam; Ameen Ghannam; Brad Buckman; Guo-Ping Wei; Wei Xu; Meina Liang; Mary Rosser; Laura Dunning; Joseph Hesselgesser; RM Snider; Michael M Morrissey; H Daniel Perez; C Green
CCR1-specific non-peptide antagonist: efficacy in a rabbit allograft rejection model.
Immunology letters 2001;76(3):193-201.
2001: Richard Horuk; C Clayberger; Alan Krensky; Z Wang; H J Grone; C Weber; Kim S C Weber; Peter J Nelson; K May; Mary Rosser; Laura Dunning; Meina Liang; Brad Buckman; Ameen Ghannam; Howard P Ng; Imadul Islam; John G Bauman; Guo-Ping Wei; S Monahan; Wei Xu; RM Snider; Michael M Morrissey; Joseph Hesselgesser; H Daniel Perez
A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection.
The Journal of biological chemistry 2001;276(6):4199-204.
2000: Meina Liang; Cornell Mallari; Mary Rosser; Howard P Ng; K May; S Monahan; John G Bauman; Imadul Islam; Ameen Ghannam; Brad Buckman; K Shaw; Guo-Ping Wei; Wei Xu; Z Zhao; E Ho; J Shen; H Oanh; Babu Subramanyam; Ronald Vergona; D Taub; Laura Dunning; S Harvey; RM Snider; Joseph Hesselgesser; Michael M Morrissey; H Daniel Perez
Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1.
The Journal of biological chemistry 2000;275(25):19000-8.
2000: Meina Liang; Mary Rosser; Howard P Ng; K May; John G Bauman; Imadul Islam; Ameen Ghannam; P J Kretschmer; H Pu; Laura Dunning; RM Snider; Michael M Morrissey; Joseph Hesselgesser; H Daniel Perez; Richard Horuk
Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor.
European journal of pharmacology 2000;389(1):41-9.
1999: Howard P Ng; K May; John G Bauman; Ameen Ghannam; Imadul Islam; Meina Liang; Richard Horuk; Joseph Hesselgesser; RM Snider; H Daniel Perez; Michael M Morrissey
Discovery of novel non-peptide CCR1 receptor antagonists.
Journal of medicinal chemistry 1999;42(22):4680-94.
1998: Joseph Hesselgesser; Howard P Ng; Meina Liang; W Zheng; K May; John G Bauman; S Monahan; Imadul Islam; Guo-Ping Wei; Ameen Ghannam; D D Taub; Mary Rosser; RM Snider; Michael M Morrissey; H Daniel Perez; Richard Horuk
Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor.
The Journal of biological chemistry 1998;273(25):15687-92.