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Ali Gharavi

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Jiri Mestecky; Zina Moldoveanu; Ali G Gharavi; Bruce A Julian; Karel Matousovic; Lea Novak; Milan Raska; Matthew B Renfrow; Jan Novak
IgA nephropathy: molecular mechanisms of the disease.
Francesca Lugani; Cathy L Mendelsohn; Virginia E Papaioannou; Natalia Papeta; Ami Patel; Ruth A Singer; Roel Sterken; Lori Sussel; Zongyu Zheng; Ripla Arora; Gianluca Caridi; Ali G Gharavi
A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse.
Krzysztof Kiryluk; Jan Novak; Ali G Gharavi
Pathogenesis of immunoglobulin A nephropathy: recent insight from genetic studies.

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All Publications

2013: Jiri Mestecky; Zina Moldoveanu; Ali G Gharavi; Bruce A Julian; Karel Matousovic; Lea Novak; Milan Raska; Matthew B Renfrow; Jan Novak
IgA nephropathy: molecular mechanisms of the disease.
Annual review of pathology 2013;8():217-40.
2013: Francesca Lugani; Cathy L Mendelsohn; Virginia E Papaioannou; Natalia Papeta; Ami Patel; Ruth A Singer; Roel Sterken; Lori Sussel; Zongyu Zheng; Ripla Arora; Gianluca Caridi; Ali G Gharavi
A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse.
PLoS genetics 2013;9(2):e1003206.
2013: Krzysztof Kiryluk; Jan Novak; Ali G Gharavi
Pathogenesis of immunoglobulin A nephropathy: recent insight from genetic studies.
Annual review of medicine 2013;64():339-56.
2012: Na Zhao; Ali G Gharavi; Ping Hou; Krzysztof Kiryluk; Yifu Li; Jicheng Lv; Zina Moldoveanu; Jan Novak; Hong Zhang
The level of galactose-deficient IgA1 in the sera of patients with IgA nephropathy is associated with disease progression.
Kidney international 2012;82(7):790-6.
2012: Jingyuan Xie; Wen Zhang; Xiaonong Chen; Ali G Gharavi; Shanmai Guo; Krzysztof Kiryluk; Xiao Li; Yifu Li; Xiaoxia Pan; Hong Ren; Pingyan Shen; Hao Shi; Weiming Wang; Zhaohui Wang; Nan Chen
Predicting progression of IgA nephropathy: new clinical progression risk score.
PloS one 2012;7(6):e38904.
2011: Natalia Papeta; Ami Patel; Michael J Ross; Holly J Snyder; Roel Sterken; Jonathan A Winston; Christina M Wyatt; Robert J Wyatt; Phil H Imus; Bruce A Julian; Nilgun Kacak; Krzysztof Kiryluk; Mary E Klotman; Paul Klotman; Anil K Lawani; Anand N Mhatre; Jan Novak; Gerald B Appel; David J Cohen; Vivette D D'Agati; Ali G Gharavi
APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy.
Journal of the American Society of Nephrology : JASN 2011;22(11):1991-6.
2011: Hitoshi Suzuki; Robert J Wyatt; Ali G Gharavi; Andrew B Herr; Krzysztof Kiryluk; Jiri Mestecky; Zina Moldoveanu; Jan Novak; Matthew B Renfrow; Francesco Scolari; Bruce A Julian
The pathophysiology of IgA nephropathy.
Journal of the American Society of Nephrology : JASN 2011;22(10):1795-803.
2011: Roberta Camilla; Alessandro Amore; Gerald B Appel; Valentina Daprà; Ali G Gharavi; Gian Marco Ghiggeri; Bruce A Julian; Elisa Loiacono; Gianna Mazzucco; Jan Novak; Licia Peruzzi; Francesco Scolari; Hitoshi Suzuki; Stéphan Troyanov; Rosanna Coppo
Oxidative stress and galactose-deficient IgA1 as markers of progression in IgA nephropathy.
Clinical journal of the American Society of Nephrology : CJASN 2011;6(8):1903-11.
2011: Simone Sanna-Cherchi; Francesco Scolari; Lawrence S Shapiro; Patricia L Weng; Maddalena A Allegretta; Landino Allegri; Monica Bodria; Katelyn E Burgess; Gianluca Caridi; Alba Carrea; Lorraine N Clark; Daniele Cusi; Vivette D'Agati; Monica Dagnino; Loreto Gesualdo; Gian Marco Ghiggeri; Maddalena Gigante; Hyunjae R Kim; Sergey Kisselev; Shannon N Nees; Teresa Palomero; Carmine Pecoraro; Brittany J Perry; Ali G Gharavi
Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome.
Kidney international 2011;80(4):389-96.
2011: Krzysztof Kiryluk; Zina Moldoveanu; Jan Novak; John T Sanders; Hitoshi Suzuki; T Matthew Eison; Ali G Gharavi; Bruce A Julian; Robert J Wyatt
Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-Schönlein purpura nephritis.
Kidney international 2011;80(1):79-87.
2011: Rosemary Thomas; Simone Sanna-Cherchi; Bradley A Warady; Susan L Furth; Frederick J Kaskel; Ali G Gharavi
HNF1B and PAX2 mutations are a common cause of renal hypodysplasia in the CKiD cohort.
Pediatric nephrology (Berlin, Germany) 2011;26(6):897-903.
2011: Natalia Papeta; Roel Sterken; Krzysztof Kiryluk; Robert Kalyesubula; Ali G Gharavi
The molecular pathogenesis of HIV-1 associated nephropathy: recent advances.
Journal of molecular medicine (Berlin, Germany) 2011;89(5):429-36.
2011: Jan Novak; Milan Raska; Yusuke Suzuki; Yasuhiko Tomino; Robert J Wyatt; Ali G Gharavi; Bruce A Julian; Jiri Mestecky; Zina Moldoveanu; Hitoshi Suzuki
Aberrant glycosylation of IgA1 and anti-glycan antibodies in IgA nephropathy: role of mucosal immune system.
Advances in oto-rhino-laryngology 2011;72():60-3.
2010: Hussein H Karnib; Ali G Gharavi; Georges Aftimos; ziyad mahfoud; Reem Saad; Elias Gemayel; Badiaa Masri; Shafika Assaad; KAMAL BADR; Fuad N Ziyadeh
A 5-year survey of biopsy proven kidney diseases in Lebanon: significant variation in prevalence of primary glomerular diseases by age, population structure and consanguinity.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(12):3962-9.
2010: Natalia Papeta; Zongyu Zheng; Eric A Schon; Sonja Brosel; Mehmet Mete Altintas; Samih H Nasr; Jochen Reiser; Vivette D D'Agati; Ali G Gharavi
Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice.
The Journal of clinical investigation 2010;120(11):4055-64.
2010: Margaret C Hastings; Zina Moldoveanu; Bruce A Julian; Jan Novak; John T Sanders; Kim R McGlothan; Ali G Gharavi; Robert J Wyatt
Galactose-deficient IgA1 in African Americans with IgA nephropathy: serum levels and heritability.
Clinical journal of the American Society of Nephrology : CJASN 2010;5(11):2069-74.
2010: Krzysztof Kiryluk; Bruce A Julian; Robert J Wyatt; Francesco Scolari; Hong Zhang; Jan Novak; Ali G Gharavi
Genetic studies of IgA nephropathy: past, present, and future.
Pediatric nephrology (Berlin, Germany) 2010;25(11):2257-68.
2010: Streamson Chua Jr.; Yifu Li; Shun Mei Liu; Ruijie Liu; Ka Tak Chan; Jeremiah Martino; Zongyu Zheng; Katalin Susztak; Vivette D D'Agati; Ali G Gharavi
A susceptibility gene for kidney disease in an obese mouse model of type II diabetes maps to chromosome 8.
Kidney international 2010;78(5):453-62.
2010: Krzysztof Kiryluk; Ali G Gharavi; Claudia Izzi; Francesco Scolari
IgA nephropathy--the case for a genetic basis becomes stronger.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010;25(2):336-8.
2009: Neal Paragas; Thomas L Nickolas; Christina Wyatt; Catherine S Forster; Meghan Sise; Susan Morgello; Bernd Jagla; Charles Buchen; Peter Stella; Simone Sanna-Cherchi; Maria Luisa Carnevali; Silvia Mattei; Achiropita Bovino; Lucia Argentiero; Andrea Magnano; Prasad Devarajan; Kai M Schmidt-Ott; Landino Allegri; Paul Klotman; Vivette D'Agati; Ali G Gharavi; Jonathan Barasch
Urinary NGAL marks cystic disease in HIV-associated nephropathy.
Journal of the American Society of Nephrology : JASN 2009;20(8):1687-92.
2009: Patricia L Weng; Simone Sanna-Cherchi; Terry W Hensle; Ellen Shapiro; Alan Werzberger; Gianluca Caridi; Claudia Izzi; Anita Konka; Adam C Reese; Rong Cheng; Samuel Werzberger; Richard N Schlussel; Robert D Burk; Joseph Lee; Roberto Ravazzolo; Francesco Scolari; Gian Marco Ghiggeri; Kenneth Glassberg; Ali G Gharavi
A recessive gene for primary vesicoureteral reflux maps to chromosome 12p11-q13.
Journal of the American Society of Nephrology : JASN 2009;20(7):1633-40.
2009: Natalia Papeta; Ka-Tak Chan; Sindhuri Prakash; Jeremiah Martino; Krzysztof Kiryluk; David Ballard; Leslie A Bruggeman; Rachelle Frankel; Zongyu Zheng; Paul Klotman; Hongyu Zhao; Vivette D D'Agati; Richard P Lifton; Ali G Gharavi
Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression.
The Journal of clinical investigation 2009;119(5):1178-88.
2009: Ka T Chan; Natalia Papeta; Jeremiah Martino; Zongyu Zheng; Rachelle Z Frankel; Paul E Klotman; Vivette D D'Agati; Richard P Lifton; Ali G Gharavi
Accelerated development of collapsing glomerulopathy in mice congenic for the HIVAN1 locus.
Kidney international 2009;75(4):366-72.
2008: Ali G Gharavi; Zina Moldoveanu; Robert Wyatt; Catherine V Barker; Susan Woodford; Richard P Lifton; Jiri Mestecky; Jan Novak; Bruce A Julian
Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy.
Journal of the American Society of Nephrology : JASN 2008;19(5):1008-14.
2007: Simone Sanna-Cherchi; Gianluca Caridi; Patricia L Weng; Francesco Scolari; Francesco Perfumo; Ali G Gharavi; Gian Marco Ghiggeri
Genetic approaches to human renal agenesis/hypoplasia and dysplasia.
Pediatric nephrology (Berlin, Germany) 2007;22(10):1675-84.
2007: Krzysztof Kiryluk; Jeremiah Martino; Ali G Gharavi
Genetic susceptibility, HIV infection, and the kidney.
Clinical journal of the American Society of Nephrology : CJASN 2007;2 Suppl 1():S25-35.
2007: Isabel Beerman; Jan Novak; Robert Wyatt; Bruce A Julian; Ali G Gharavi
The genetics of IgA nephropathy.
Nature clinical practice. Nephrology 2007;3(6):325-38.
2007: Simone Sanna-Cherchi; Gianluca Caridi; Patricia L Weng; Monica Dagnino; Marco Seri; Anita Konka; Danio Somenzi; Alba Carrea; Claudia Izzi; Domenica Casu; Landino Allegri; Kai M Schmidt-Ott; Jonathan Barasch; Francesco Scolari; Roberto Ravazzolo; Gian Marco Ghiggeri; Ali G Gharavi
Localization of a gene for nonsyndromic renal hypodysplasia to chromosome 1p32-33.
American journal of human genetics 2007;80(3):539-49.
2007: Hussein H Karnib; Simone Sanna-Cherchi; Pierre A Zalloua; Walid Medawar; Vivette D D'Agati; Richard P Lifton; KAMAL BADR; Ali G Gharavi
Characterization of a large Lebanese family segregating IgA nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(3):772-7.
2007: H H Karnib; Streamson Chua Jr.; Ali G Gharavi
Genes for diabetic nephropathy: sweet prospects on the horizon.
Kidney international 2007;71(2):94-6.
2006: Zongyu Zheng; Paul Pavlidis; Streamson Chua Jr.; Vivette D D'Agati; Ali G Gharavi
An ancestral haplotype defines susceptibility to doxorubicin nephropathy in the laboratory mouse.
Journal of the American Society of Nephrology : JASN 2006;17(7):1796-800.
2006: Claudia Izzi; Simone Sanna-Cherchi; Elisabetta Prati; R Belleri; A Remedio; Regina Tardanico; Marina Foramitti; Simona Guerini; Battista Fabio Viola; Ezio Movilli; I Beerman; Richard P Lifton; L Leone; Ali G Gharavi; Francesco Scolari
Familial aggregation of primary glomerulonephritis in an Italian population isolate: Valtrompia study.
Kidney international 2006;69(6):1033-40.
2005: Simone Sanna-Cherchi; Adam Reese; Terry W Hensle; Gianluca Caridi; Claudia Izzi; You Yeun Kim; Anita Konka; Luisa Murer; Francesco Scolari; Roberto Ravazzolo; Gian Marco Ghiggeri; Ali G Gharavi
Familial vesicoureteral reflux: testing replication of linkage in seven new multigenerational kindreds.
Journal of the American Society of Nephrology : JASN 2005;16(6):1781-7.
2005: Zongyu Zheng; Kai M Schmidt-Ott; Streamson Chua Jr.; Kirk A Foster; Rachelle Z Frankel; Paul Pavlidis; Jonathan Barasch; Vivette D D'Agati; Ali G Gharavi
A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(7):2502-7.
2004: Giovanni M Frascá; Letizia Soverini; Ali G Gharavi; Richard P Lifton; Cristina Canova; Paola Preda; Alba Vangelista; Sergio Stefoni
Thin basement membrane disease in patients with familial IgA nephropathy.
Journal of nephrology 2004;17(6):778-85.
2004: Sonia Davila; Laszlo Furu; Ali G Gharavi; Xin Tian; Tamehito Onoe; Qi Qian; Airong Li; Yiqiang Cai; Patrick S Kamath; Bernard F King; Pablo J Azurmendi; Pia Tahvanainen; Helena Kääriäinen; Krister Höckerstedt; Olivier Devuyst; Yves Pirson; Rodolfo S Martin; Richard P Lifton; Esa Tahvanainen; Vicente E Torres; Stefan Somlo
Mutations in SEC63 cause autosomal dominant polycystic liver disease.
Nature genetics 2004;36(6):575-7.
2004: Ali G Gharavi; Tariq Ahmad; Robert D Wong; Roozbeh Hooshyar; Janene Vaughn; Sarah Oller; Rachelle Z Frankel; Leslie A Bruggeman; Vivette D D'Agati; Paul E Klotman; Richard P Lifton
Mapping a locus for susceptibility to HIV-1-associated nephropathy to mouse chromosome 3.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2488-93.
2003: Laszlo Furu; Luiz F Onuchic; Ali G Gharavi; Xiaoying Hou; Ernie L Esquivel; Yasuyuki Nagasawa; Carsten Bergmann; Jan Senderek; Ellis D Avner; Klaus Zerres; Gregory G Germino; Lisa M Guay-Woodford; Stefan Somlo
Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations.
Journal of the American Society of Nephrology : JASN 2003;14(8):2004-14.
2002: Noel M Delos Santos; Bettina H Ault; Ali G Gharavi; Stephen B Kritchevsky; Michael W Quasney; Elizabeth C Jackson; Kimberly A Fisher; Susan Woodford; Bonnie L Mitchell; Lillian W Gaber; Kristopher L Arheart; Robert Wyatt
Angiotensin-converting enzyme genotype and outcome in pediatric IgA nephropathy.
Pediatric nephrology (Berlin, Germany) 2002;17(7):496-502.
2000: Ali G Gharavi; Y Yan; Francesco Scolari; Francesco Paolo Schena; G M Frasca; Gian Marco Ghiggeri; K Cooper; Antonio Amoroso; Battista Fabio Viola; G Battini; Gianluca Caridi; Cristina Canova; anita farhi; V Subramanian; Carol Nelson-Williams; Susan Woodford; B A Julian; Robert Wyatt; Richard P Lifton
IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23.
Nature genetics 2000;26(3):354-7.