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Vazganush Gharibyan

Research Profile

Physiology

Chemicals & Drugs

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Noël J-M Raynal; Jiali Si; Rodolphe F Taby; Jaroslav Jelinek; Saira Ahmed; Marcos R H Estécio; Vazganush Gharibyan; Jean-Pierre J Issa
DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory.
Astrid Spannhoff; Yong Kee Kim; Noel J-M Raynal; Vazganush Gharibyan; Ming-Bo Su; Yue-Yang Zhou; Jia Li; Sabrina Castellano; Gianluca Sbardella; Jean-Pierre J Issa; Mark T Bedford
Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees.
Yanis A Boumber; Yutaka Kondo; Xuqi Chen; Lanlan Shen; Vazganush Gharibyan; Kazuo Konishi; Elihu Estey; Andrew Lamb; Guillermo Garcia-Manero; Jean-Pierre J Issa
RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis.

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2012: Noël J-M Raynal; Jiali Si; Rodolphe F Taby; Jaroslav Jelinek; Saira Ahmed; Marcos R H Estécio; Vazganush Gharibyan; Jean-Pierre J Issa
DNA methylation does not stably lock gene expression but instead serves as a molecular mark for gene silencing memory.
Cancer research 2012;72(5):1170-81.
2011: Astrid Spannhoff; Yong Kee Kim; Noel J-M Raynal; Vazganush Gharibyan; Ming-Bo Su; Yue-Yang Zhou; Jia Li; Sabrina Castellano; Gianluca Sbardella; Jean-Pierre J Issa; Mark T Bedford
Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees.
EMBO reports 2011;12(3):238-43.
2007: Yanis A Boumber; Yutaka Kondo; Xuqi Chen; Lanlan Shen; Vazganush Gharibyan; Kazuo Konishi; Elihu Estey; Andrew Lamb; Guillermo Garcia-Manero; Jean-Pierre J Issa
RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis.
Cancer research 2007;67(5):1997-2005.
2007: Yasuhiro Oki; Hagop M Kantarjian; Vazganush Gharibyan; Dan Jones; Susan O'Brien; Srdan Verstovsek; Jorge Cortes; Gail M Morris; Guillermo Garcia-Manero; Jean-Pierre J Issa
Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia.
Cancer 2007;109(5):899-906.
2007: Marcos R H Estécio; Vazganush Gharibyan; Lanlan Shen; Ashraf E K Ibrahim; Ketan Doshi; Rong He; Jaroslav Jelinek; Allen S Yang; Pearlly S Yan; Hui-Ming (Tim) Huang; Eloiza H Tajara; Jean-Pierre J Issa
LINE-1 hypomethylation in cancer is highly variable and inversely correlated with microsatellite instability.
PloS one 2007;2(5):e399.
2005: Jaroslav Jelinek; Yasuhiro Oki; Vazganush Gharibyan; Carlos E Bueso-Ramos; Josef T Prchal; Srdan Verstovsek; Miloslav Beran; Elihu Estey; Hagop M Kantarjian; Jean-Pierre J Issa
JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia.
Blood 2005;106(10):3370-3.
2005: Jean-Pierre J Issa; Vazganush Gharibyan; Jorge Cortes; Jaroslav Jelinek; Gail Morris; Srdan Verstovsek; Moshe Talpaz; Guillermo Garcia-Manero; Hagop M Kantarjian
Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(17):3948-56.