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Peter Ghazal

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Holly C Gibbs; Garwin Sing; Colin J Campbell; Peter Ghazal; Juan Carlos González Armas; Alvin T Yeh
Time-lapse ultrashort pulse microscopy of infection in three-dimensional versus two-dimensional culture environments reveals enhanced extra-chromosomal virus replication compartment formation.
Steven Watterson; Markus R Wenk; Mathieu Blanc; Holly Gibbs; Maria Luisa Guerriero; Jane Hillston; Laurence Loewe; Alexander Mazein; Kevin A Robertson; Guanghou Shui; Peter Ghazal
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction.
Mathieu Blanc; Douglas F Covey; Marie Craigon; Thorsten Forster; Ana Angulo; Christopher K Glass; Samantha J Griffiths; William J Griffiths; Jürgen Haas; Wei Yuan Hsieh; Kathiresan Krishnan; Kai A Kropp; Paul Lacaze; Anna Meljon; Kevin A Robertson; Zsolts Ruzsics; Guanghou Shui; Nathanael J Spann; Simon Talbot; Yuqin Wang; Steven Watterson; Markus R Wenk; Peter Ghazal
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.

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2013: Holly C Gibbs; Garwin Sing; Colin J Campbell; Peter Ghazal; Juan Carlos González Armas; Alvin T Yeh
Time-lapse ultrashort pulse microscopy of infection in three-dimensional versus two-dimensional culture environments reveals enhanced extra-chromosomal virus replication compartment formation.
Journal of biomedical optics 2013;18(3):031111.
2013: Steven Watterson; Markus R Wenk; Mathieu Blanc; Holly Gibbs; Maria Luisa Guerriero; Jane Hillston; Laurence Loewe; Alexander Mazein; Kevin A Robertson; Guanghou Shui; Peter Ghazal
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction.
Biochimie 2013;95(3):613-21.
2013: Mathieu Blanc; Douglas F Covey; Marie Craigon; Thorsten Forster; Ana Angulo; Christopher K Glass; Samantha J Griffiths; William J Griffiths; Jürgen Haas; Wei Yuan Hsieh; Kathiresan Krishnan; Kai A Kropp; Paul Lacaze; Anna Meljon; Kevin A Robertson; Zsolts Ruzsics; Guanghou Shui; Nathanael J Spann; Simon Talbot; Yuqin Wang; Steven Watterson; Markus R Wenk; Peter Ghazal
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.
Immunity 2013;38(1):106-18.
2013: M Piotrowski; T M Sloan; Thorsten Forster; Peter Ghazal; A D Lloyd; G A McGilvary; Muriel Mewissen; L Mitchell; J Hill
Exploiting parallel R in the cloud with SPRINT.
Methods of information in medicine 2013;52(1):80-90.
2012: Damion Corrigan; Jason Crain; Peter Ghazal; Gerard Giraud; Grace Henihan; Andrew R Mount; Ronald Pethig; Holger Schulze; Jonathan G Terry; Anthony J Walton; Colin J Campbell; Ilenia Ciani; Till T Bachmann
Impedimetric detection of single-stranded PCR products derived from methicillin resistant Staphylococcus aureus (MRSA) isolates.
Biosensors & bioelectronics 2012;34(1):178-84.
2012: Sara Rodríguez-Martín; Hille Tekotte; Vanessa Wilhelmi; Ana Angulo; Manfred Auer; Mathieu Blanc; Andreas Busche; Iain Fraser; Wei Yuan Hsieh; Stipan Jonjic; Kai Alexander Kropp; Vanda Juranic Lisnic; Andrew Livingston; Martin Messerle; Matthias J Reddehase; Peter Ghazal
Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection.
PLoS pathogens 2012;8(8):e1002901.
2011: Stuart W J Ember; Peter Ghazal; Gerard Giraud; Mizanur Khondoker; Julie Luby; Andrew R Mount; Alan J Ross; Holger Schulze; Jonathan G Terry; Chaker Tlili; Anthony J Walton; Till Bachmann; Ilenia Ciani; Jason Crain; Colin J Campbell
Fast DNA and protein microarray tests for the diagnosis of hepatitis C virus infection on a single platform.
Analytical and bioanalytical chemistry 2011;401(8):2549-59.
2011: Kai A Kropp; Paul Lacaze; Mathias Mueller; Kevin A Robertson; Sara Rodriguez-Martin; Garwin Sing; Birgit Strobl; Ana Angulo; Mathieu Blanc; Andreas Busche; Paul Dickinson; Thorsten Forster; Muhamad F B Noor Hassim; Stipan Jonjic; Mizanur R Khondoker; Peter Ghazal
Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state.
Journal of virology 2011;85(19):10286-99.
2011: Pablo Engel; Peter Ghazal; Natàlia Pérez-Carmona; Kevin Robertson; M Mar Albà; Ana Angulo
Human cytomegalovirus UL7, a homologue of the SLAM-family receptor CD229, impairs cytokine production.
Immunology and cell biology 2011;89(7):753-66.
2011: Gerard Giraud; Grace Henihan; Anoop Menachery; Andrew R Mount; Ronald Pethig; Holger Schulze; Jonathan G Terry; Anthony J Walton; Colin J Campbell; Ilenia Ciani; Damion Corrigan; Jason Crain; Peter Ghazal; Till Bachmann
Dielectrophoretic manipulation of ribosomal RNA.
Biomicrofluidics 2011;5(2):24116.
2011: Paul Lacaze; Thorsten Forster; Alan Ross; Lorraine E Kerr; Eliane Salvo-Chirnside; Vanda Juranic Lisnic; Guillermo H López-Campos; José J García-Ramírez; Martin Messerle; Joanne Trgovcich; Ana Angulo; Peter Ghazal
Temporal profiling of the coding and noncoding murine cytomegalovirus transcriptomes.
Journal of virology 2011;85(12):6065-76.
2011: Mathieu Blanc; Wei Yuan Hsieh; Kevin A Robertson; Steven Watterson; Guanghou Shui; Paul Lacaze; Mizanur Khondoker; Paul Dickinson; Garwin Sing; Sara Rodríguez-Martín; Peter Phelan; Thorsten Forster; Birgit Strobl; Matthias Müller; Rudolph Riemersma; Timothy Osborne; Markus R Wenk; Ana Angulo; Peter Ghazal
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis.
PLoS biology 2011;9(3):e1000598.
2011: Elena Isern; Montse Gustems; Martin Messerle; Eva Borst; Peter Ghazal; Ana Angulo
The activator protein 1 binding motifs within the human cytomegalovirus major immediate-early enhancer are functionally redundant and act in a cooperative manner with the NF-{kappa}B sites during acute infection.
Journal of virology 2011;85(4):1732-46.
2011: Holger Schulze; Alan J Ross; Stuart W J Ember; Julie Luby; Mizanur Khondoker; Gerard Giraud; Ilenia Ciani; Chaker Tlili; Davide Papale; Jonathan G Terry; Andrew R Mount; Anthony J Walton; Jason Crain; Peter Ghazal; Till Bachmann; Colin J Campbell
Peptide-tags for enhanced DNA microarray performance.
Faraday discussions 2011;149():201-10; discussion 227-45.
2011: Peter Ghazal; Kevin Robertson; Steven Watterson; David C Kluth
The in silico macrophage: toward a better understanding of inflammatory disease.
Genome medicine 2011;3(1):4.
2010: Mizanur R Khondoker; Till Bachmann; Muriel Mewissen; Paul Dickinson; Bartosz Dobrzelecki; Colin J Campbell; Andrew R Mount; Anthony J Walton; Jason Crain; Holger Schulze; Gerard Giraud; Alan J Ross; Ilenia Ciani; Stuart W J Ember; Chaker Tlili; Jonathan G Terry; Eilidh Grant; Nicola McDonnell; Peter Ghazal
Multi-factorial analysis of class prediction error: estimating optimal number of biomarkers for various classification rules.
Journal of bioinformatics and computational biology 2010;8(6):945-65.
2010: G H Ashrafi; Esther Grinfeld; Paul Montague; Thorsten Forster; Alan Ross; Peter Ghazal; Fiona Scott; Judith Breuer; Roslyn Goodwin; Peter G E Kennedy
Assessment of transcriptomal analysis of Varicella-Zoster-virus gene expression in patients with and without post-herpetic neuralgia.
Virus genes 2010;41(2):192-201.
2010: Diwakar Santhakumar; Thorsten Forster; Nouf N Laqtom; Rennos Fragkoudis; Paul Dickinson; Cei Abreu-Goodger; Sergei A Manakov; Nila Roy Choudhury; Samantha J Griffiths; Annaleen Vermeulen; Anton J Enright; Bernadette Dutia; Alain Kohl; Peter Ghazal; Amy H Buck
Combined agonist-antagonist genome-wide functional screening identifies broadly active antiviral microRNAs.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(31):13830-5.
2010: Steven Watterson; Peter Ghazal
Use of logic theory in understanding regulatory pathway signaling in response to infection.
Future microbiology 2010;5(2):163-76.
2010: Colin D McGuinness; Mira K Y Nishimura; David Keszenman-Pereyra; Paul Dickinson; Colin J Campbell; Till Bachmann; Peter Ghazal; Jason Crain
Detection of single nucleotide polymorphisms using a DNA Holliday junction nanoswitch--a high-throughput fluorescence lifetime assay.
Molecular bioSystems 2010;6(2):386-90.
2010: Tom C Freeman; Sobia Raza; Athanasios Theocharidis; Peter Ghazal
The mEPN scheme: an intuitive and flexible graphical system for rendering biological pathways.
BMC systems biology 2010;4():65.
2010: Sobia Raza; Neil McDerment; Paul A Lacaze; Kevin Robertson; Steven Watterson; Ying Chen; Michael Chisholm; George Eleftheriadis; Stephanie Monk; Maire O'Sullivan; Arran Turnbull; Douglas Roy; Athanasios Theocharidis; Peter Ghazal; Tom C Freeman
Construction of a large scale integrated map of macrophage pathogen recognition and effector systems.
BMC systems biology 2010;4():63.
2009: Colin J Campbell; Christopher P Mountford; Helene C Stoquert; Amy H Buck; Paul Dickinson; Elena Ferapontova; Jonathan G Terry; John S Beattie; Anthony J Walton; Jason Crain; Peter Ghazal; Andrew R Mount
A DNA nanoswitch incorporating the fluorescent base analogue 2-aminopurine detects single nucleotide mismatches in unlabelled targets.
The Analyst 2009;134(9):1873-9.
2009: A W Horne; W Colin Duncan; Anne E King; S Burgess; PC Lourenco; Pamela Ann cornes; Peter Ghazal; Alistair R W Williams; L Udby; Hilary Critchley
Endometrial cysteine-rich secretory protein 3 is inhibited by human chorionic gonadotrophin, and is increased in the decidua of tubal ectopic pregnancy.
Molecular human reproduction 2009;15(5):287-94.
2009: Andreas Busche; Anja Marquardt; Andre Bleich; Peter Ghazal; Ana Angulo; Martin Messerle
The mouse cytomegalovirus immediate-early 1 gene is not required for establishment of latency or for reactivation in the lungs.
Journal of virology 2009;83(9):4030-8.
2009: Gerard Giraud; Holger Schulze; Till Bachmann; Colin J Campbell; Andrew R Mount; Peter Ghazal; Mizanur R Khondoker; Alan J Ross; Stuart W Ember; Ilenia Ciani; Chaker Tlili; Anthony J Walton; Jonathan G Terry; Jason Crain
Fluorescence lifetime imaging of quantum dot labeled DNA microarrays.
International journal of molecular sciences 2009;10(4):1930-41.
2009: Esther Grinfeld; Alan Ross; Thorsten Forster; Peter Ghazal; Peter G E Kennedy
Genome-wide reduction in transcriptomal profiles of varicella-zoster virus vaccine strains compared with parental Oka strain using long oligonucleotide microarrays.
Virus genes 2009;38(1):19-29.
2009: Sarah Kabani; Katelyn Fenn; Alan Ross; Alasdair Ivens; Terry K Smith; Peter Ghazal; Keith Matthews
Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei.
BMC genomics 2009;10():427.
2009: Paul Lacaze; Sobia Raza; Garwin Sing; David Page; Thorsten Forster; Petter Storm; Marie Craigon; Tarif Awad; Peter Ghazal; Tom C Freeman
Combined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signalling.
BMC genomics 2009;10():372.
2008: Elena E Ferapontova; Christopher P Mountford; J Crain; A H Buck; Paul Dickinson; J S Beattie; Peter Ghazal; Jonathan G Terry; A J Walton; A R Mount
Electrochemical control of a DNA Holliday Junction nanoswitch by Mg2+ ions.
Biosensors & bioelectronics 2008;24(3):422-8.
2008: Stewart T G Burgess; Fiona Kenyon; Nichola O'Looney; Alan J Ross; Marisa Chong Kwan; John S Beattie; Juraj Petrik; Peter Ghazal; Colin J Campbell
A multiplexed protein microarray for the simultaneous serodiagnosis of human immunodeficiency virus/hepatitis C virus infection and typing of whole blood.
Analytical biochemistry 2008;382(1):9-15.
2008: Montse Gustems; Andreas Busche; Martin Messerle; Peter Ghazal; Ana Angulo
In vivo competence of murine cytomegalovirus under the control of the human cytomegalovirus major immediate-early enhancer in the establishment of latency and reactivation.
Journal of virology 2008;82(20):10302-7.
2008: Marco Grzegorczyk; Dirk Husmeier; Kieron D Edwards; Peter Ghazal; Andrew J Millar
Modelling non-stationary gene regulatory processes with a non-homogeneous Bayesian network and the allocation sampler.
Bioinformatics (Oxford, England) 2008;24(18):2071-8.
2008: Rosemary A L Bayne; Thorsten Forster; Stewart T G Burgess; Marie Craigon; Melanie J Walton; David T Baird; Peter Ghazal; Richard A Anderson
Molecular profiling of the human testis reveals stringent pathway-specific regulation of RNA expression following gonadotropin suppression and progestogen treatment.
Journal of andrology 2008;29(4):389-403.
2008: Andreas Busche; Ana Angulo; Penelope Kay-Jackson; Peter Ghazal; Martin Messerle
Phenotypes of major immediate-early gene mutants of mouse cytomegalovirus.
Medical microbiology and immunology 2008;197(2):233-40.
2008: Steven Watterson; Stephen Marshall; Peter Ghazal
Logic models of pathway biology.
Drug discovery today 2008;13(9-10):447-56.
2008: Sofia Papadia; Francesc X Soriano; Frédéric Léveillé; Marc-Andre Martel; Kelly A Dakin; Henrik H Hansen; Angela Kaindl; Marco Sifringer; Jill Fowler; Vanya Stefovska; Grahame McKenzie; Marie Craigon; Roderick Corriveau; Peter Ghazal; Karen Horsburgh; Bruce A Yankner; David J A Wyllie; Chrysanthy Ikonomidou; Giles E Hardingham
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.
Nature neuroscience 2008;11(4):476-87.
2008: Christopher P Mountford; Amy H Buck; Colin J Campbell; Paul Dickinson; Elena E Ferapontova; Jonathan G Terry; John S Beattie; Anthony J Walton; Peter Ghazal; Andrew R Mount; Jason Crain
Molecular recognition with DNA nanoswitches: effects of single base mutations on structure.
The journal of physical chemistry. B 2008;112(8):2439-44.
2008: Jon Hill; Matthew Hambley; Thorsten Forster; Muriel Mewissen; Terence M Sloan; Florian Scharinger; Arthur Trew; Peter Ghazal
SPRINT: a new parallel framework for R.
BMC bioinformatics 2008;9():558.
2008: Sobia Raza; Kevin A Robertson; Paul A Lacaze; David Page; Anton J Enright; Peter Ghazal; Tom C Freeman
A logic-based diagram of signalling pathways central to macrophage activation.
BMC systems biology 2008;2():36.
2008: Nichola O'Looney; Stewart T G Burgess; Marisa Chong Kwan; Alan J Ross; Janine Robb; Thorsten Forster; John S Beattie; Peter Ghazal; Juraj Petrik; Colin J Campbell
Evaluation of a protein microarray method for immuno-typing erythrocytes in whole blood.
Journal of immunoassay & immunochemistry 2008;29(2):197-209.
2008: Gordon Y C Cheung; Paul Dickinson; Garwin Sing; Marie Craigon; Peter Ghazal; Roger Parton; John G Coote
Transcriptional responses of murine macrophages to the adenylate cyclase toxin of Bordetella pertussis.
Microbial pathogenesis 2008;44(1):61-70.
2007: Claire L Smith; Paul Dickinson; Thorsten Forster; Mizanur Khondoker; Marie Craigon; Alan Ross; Petter Storm; Stewart Burgess; Paul Lacaze; Benjamin J Stenson; Peter Ghazal
Quantitative assessment of human whole blood RNA as a potential biomarker for infectious disease.
The Analyst 2007;132(12):1200-9.
2007: Amy H Buck; Javier Santoyo-Lopez; Kevin A Robertson; Diwakar S Kumar; Martin Reczko; Peter Ghazal
Discrete clusters of virus-encoded micrornas are associated with complementary strands of the genome and the 7.2-kilobase stable intron in murine cytomegalovirus.
Journal of virology 2007;81(24):13761-70.
2007: Amy H Buck; Colin J Campbell; Paul Dickinson; Christopher P Mountford; Hélène C Stoquert; Jonathan G Terry; Stuart A G Evans; Lorraine M Keane; Tsueu-Ju Su; Andrew R Mount; Anthony J Walton; John S Beattie; Jason Crain; Peter Ghazal
DNA nanoswitch as a biosensor.
Analytical chemistry 2007;79(12):4724-8.
2006: Jonathan G Terry; Colin J Campbell; Alan J Ross; Andrew D Livingston; Amy H Buck; Paul Dickinson; Christopher P Mountford; Stuart A G Evans; Andrew R Mount; John S Beattie; Jason Crain; Peter Ghazal; Anthony J Walton
Improved silicon nitride surfaces for next-generation microarrays.
Langmuir : the ACS journal of surfaces and colloids 2006;22(26):11400-4.
2006: Andrew R Mount; Christopher P Mountford; Stuart A G Evans; Tsueu-Ju Su; Amy H Buck; Paul Dickinson; Colin J Campbell; L M Keane; Jonathan G Terry; John S Beattie; Anthony J Walton; Peter Ghazal; Jason Crain
The stability and characteristics of a DNA Holliday junction switch.
Biophysical chemistry 2006;124(3):214-21.
2006: Christopher P Mountford; Andrew R Mount; Stuart A G Evans; Tsueu-Ju Su; Paul Dickinson; Amy H Buck; Colin J Campbell; Jonathan G Terry; John S Beattie; Anthony J Walton; Peter Ghazal; Jason Crain
Time-resolved FRET and FLIM of four-way DNA junctions.
Journal of fluorescence 2006;16(6):839-45.
2006: Montse Gustems; Eva Borst; Chris A Benedict; Carmen Pérez; Martin Messerle; Peter Ghazal; Ana Angulo
Regulation of the transcription and replication cycle of human cytomegalovirus is insensitive to genetic elimination of the cognate NF-kappaB binding sites in the enhancer.
Journal of virology 2006;80(19):9899-904.
2006: G R Grimes; T Q Wen; Muriel Mewissen; R M Baxter; S Moodie; John S Beattie; Peter Ghazal
PDQ Wizard: automated prioritization and characterization of gene and protein lists using biomedical literature.
Bioinformatics (Oxford, England) 2006;22(16):2055-7.
2006: Hilary Critchley; Kevin A Robertson; Thorsten Forster; Teresa A Henderson; Alistair R W Williams; Peter Ghazal
Gene expression profiling of mid to late secretory phase endometrial biopsies from women with menstrual complaint.
American journal of obstetrics and gynecology 2006;195(2):406.e1-16.
2006: Michael Allen; Thorsten Forster; Declan C Schroeder; Matthew Hall; Douglas Roy; Peter Ghazal; William H Wilson
Locus-specific gene expression pattern suggests a unique propagation strategy for a giant algal virus.
Journal of virology 2006;80(15):7699-705.
2006: José Santiago Aguilar; GV Devi-Rao; Marcia K Rice; J Sunabe; Peter Ghazal; Edward K Wagner
Quantitative comparison of the HSV-1 and HSV-2 transcriptomes using DNA microarray analysis.
Virology 2006;348(1):233-41.
2006: J S Robb; Douglas J Roy; Peter Ghazal; J Allan; Juraj Petrik
Development of non-agglutination microarray blood grouping.
Transfusion medicine (Oxford, England) 2006;16(2):119-29.
2006: Colin J Campbell; Nichola O'Looney; Marisa Chong Kwan; Janine S Robb; Alan J Ross; John S Beattie; Juraj Petrik; Peter Ghazal
Cell interaction microarray for blood phenotyping.
Analytical chemistry 2006;78(6):1930-8.
2005: Peter G E Kennedy; Esther Grinfeld; Marie Craigon; Klemens Vierlinger; Douglas Roy; Thorsten Forster; Peter Ghazal
Transcriptomal analysis of varicella-zoster virus infection using long oligonucleotide-based microarrays.
The Journal of general virology 2005;86(Pt 10):2673-84.
2005: Aroosha Laghaee; Chris Malcolm; John Hallam; Peter Ghazal
Artificial intelligence and robotics in high throughput post-genomics.
Drug discovery today 2005;10(18):1253-9.
2005: William H Wilson; Declan C Schroeder; Michael Allen; Matthew T G Holden; Julian Parkhill; Bart Barrell; Carol Churcher; Nancy Hamlin; Karen Mungall; Halina Norbertczak; Michael A Quail; Claire Price; Ester Rabbinowitsch; Danielle Walker; Marie Craigon; Douglas Roy; Peter Ghazal
Complete genome sequence and lytic phase transcription profile of a Coccolithovirus.
Science (New York, N.Y.) 2005;309(5737):1090-2.
2005: Peter Ghazal; Astrid E Visser; Montse Gustems; Rosalía García; Eva Borst; Kevin Sullivan; Martin Messerle; Ana Angulo
Elimination of ie1 significantly attenuates murine cytomegalovirus virulence but does not alter replicative capacity in cell culture.
Journal of virology 2005;79(11):7182-94.
2005: Graeme R Grimes; Stuart Moodie; John S Beattie; Marie Craigon; Paul Dickinson; Thorsten Forster; Andrew D Livingston; Muriel Mewissen; Kevin A Robertson; Alan J Ross; Garwin Sing; Peter Ghazal
GPX-Macrophage Expression Atlas: a database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults.
BMC genomics 2005;6():178.
2005: Andrew D Livingston; Colin J Campbell; Edward K Wagner; Peter Ghazal
Biochip sensors for the rapid and sensitive detection of viral disease.
Genome biology 2005;6(6):112.
2005: José Santiago Aguilar; Peter Ghazal; Edward K Wagner
Design of a herpes simplex virus type 2 long oligonucleotide-based microarray: global analysis of HSV-2 transcript abundance during productive infection.
Methods in molecular biology (Clifton, N.J.) 2005;292():423-48.
2004: Gamze Karaca; Danna Hargett; Tim I McLean; José Santiago Aguilar; Peter Ghazal; Edward K Wagner; Steven L Bachenheimer
Inhibition of the stress-activated kinase, p38, does not affect the virus transcriptional program of herpes simplex virus type 1.
Virology 2004;329(1):142-56.
2004: Aixu Sun; GV Devi-Rao; Marcia K Rice; L W Gary; David Bloom; Rozanne M Sandri-Goldin; Peter Ghazal; Edward K Wagner
Immediate-early expression of the herpes simplex virus type 1 ICP27 transcript is not critical for efficient replication in vitro or in vivo.
Journal of virology 2004;78(19):10470-8.
2004: Kevin L Garwood; Thomas McLaughlin; Christopher Garwood; Scott Joens; Norman Morrison; Christopher Taylor; Kathleen Carroll; Caroline Evans; Anthony D Whetton; Sarah Hart; David Stead; Zhikang Yin; Alistair J P Brown; Andy Hesketh; Keith F Chater; Lena Hansson; Muriel Mewissen; Peter Ghazal; Julie Howard; Kathryn S Lilley; Simon J Gaskell; Andrew Brass; Simon Hubbard; Stephen G Oliver; Norman W Paton
PEDRo: a database for storing, searching and disseminating experimental proteomics data.
BMC genomics 2004;5():68.
2004: Chris A Benedict; Ana Angulo; Ginelle Patterson; Sukwon Ha; Huang Huang; Martin Messerle; Carl Ware; Peter Ghazal
Neutrality of the canonical NF-kappaB-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro.
Journal of virology 2004;78(2):741-50.
2004: Colin J Campbell; Peter Ghazal
Molecular signatures for diagnosis of infection: application of microarray technology.
Journal of applied microbiology 2004;96(1):18-23.
2003: Jerome Aubert; Marios P Stavridis; Susan Tweedie; Michelle O'Reilly; Klemens Vierlinger; Meng Li; Peter Ghazal; Thomas Pratt; John O Mason; Douglas Roy; Austin Smith
Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100 Suppl 1():11836-41.
2003: Peter Ghazal; Martin Messerle; Kent Osborn; Ana Angulo
An essential role of the enhancer for murine cytomegalovirus in vivo growth and pathogenesis.
Journal of virology 2003;77(5):3217-28.
2003: Dan J Von Seggern; Edith Aguilar; Karen Kinder; Shonna Kaye Fleck; J C Gonzalez Armas; Susan C Stevenson; Peter Ghazal; Glen R Nemerow; Martin Friedlander
In vivo transduction of photoreceptors or ciliary body by intravitreal injection of pseudotyped adenoviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(1):27-34.
2003: Bahram Ebrahimi; Bernadette M Dutia; Kim L Roberts; Jose J Garcia-Ramirez; Paul Dickinson; James P Stewart; Peter Ghazal; Douglas J Roy; Anthony A Nash
Transcriptome profile of murine gammaherpesvirus-68 lytic infection.
The Journal of general virology 2003;84(Pt 1):99-109.
2002: William C Yang; GV Devi-Rao; Peter Ghazal; Edward K Wagner; Steven J Triezenberg
General and specific alterations in programming of global viral gene expression during infection by VP16 activation-deficient mutants of herpes simplex virus type 1.
Journal of virology 2002;76(24):12758-74.
2002: José Santiago Aguilar; D Roy; Peter Ghazal; Edward K Wagner
Dimethyl sulfoxide blocks herpes simplex virus-1 productive infection in vitro acting at different stages with positive cooperativity. Application of micro-array analysis.
BMC infectious diseases 2002;2():9.
2002: Douglas Roy; Thorsten Forster; Sean McGeever; Kevin Robertson; Peter Ghazal
Meeting review: Bioinformatics of biochips: accelerating discovery in functional genomics.
Comparative and functional genomics 2002;3(4):380-6.
2002: Edward K Wagner; J J Garcia Ramirez; S W N Stingley; Santiago Aguilar; L Buehler; Gayathri B Devi-Rao; Peter Ghazal
Practical approaches to long oligonucleotide-based DNA microarray: lessons from herpesviruses.
Progress in nucleic acid research and molecular biology 2002;71():445-91.
2001: Chris A Benedict; Theresa A Banks; L Senderowicz; M Ko; W J Britt; Ana Angulo; Peter Ghazal; Carl Ware
Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus détente.
Immunity 2001;15(4):617-26.
2001: S Redpath; Peter Ghazal; Nicholas R J Gascoigne
Hijacking and exploitation of IL-10 by intracellular pathogens.
Trends in microbiology 2001;9(2):86-92.
2001: S Redpath; Ana Angulo; Nicholas R J Gascoigne; Peter Ghazal
Immune checkpoints in viral latency.
Annual review of microbiology 2001;55():531-60.
2001: JJ García-Ramírez; F Ruchti; H Huang; K Simmen; Ana Angulo; Peter Ghazal
Dominance of virus over host factors in cross-species activation of human cytomegalovirus early gene expression.
Journal of virology 2001;75(1):26-35.
2000: Ana Angulo; Peter Ghazal; Martin Messerle
The major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth.
Journal of virology 2000;74(23):11129-36.
2000: S W Stingley; J J Ramirez; Santiago Aguilar; K Simmen; Rozanne M Sandri-Goldin; Peter Ghazal; Edward K Wagner
Global analysis of herpes simplex virus type 1 transcription using an oligonucleotide-based DNA microarray.
Journal of virology 2000;74(21):9916-27.
2000: Peter Ghazal; J C González Armas; JJ García-Ramírez; Sabine K Kurz; Ana Angulo
Viruses: hostages to the cell.
Virology 2000;275(2):233-7.
2000: Ana Angulo; D Kerry; H Huang; Eva Borst; A Razinsky; J Wu; U Hobom; Martin Messerle; Peter Ghazal
Identification of a boundary domain adjacent to the potent human cytomegalovirus enhancer that represses transcription of the divergent UL127 promoter.
Journal of virology 2000;74(6):2826-39.
2000: H Wang; M N Griffiths; Dennis R Burton; Peter Ghazal
Rapid antibody responses by low-dose, single-step, dendritic cell-targeted immunization.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):847-52.
2000: Peter Ghazal; JJ García-Ramírez; J C González-Armas; Sabine K Kurz; Ana Angulo
Principles of homeostasis in governing virus activation and latency.
Immunologic research 2000;21(2-3):219-23.
1999: T Preckel; Wai-Ping Fung-Leung; Z Cai; Antonella Vitiello; L Salter-Cid; Ola Winqvist; Tom Wolfe; M Von Herrath; Ana Angulo; Peter Ghazal; J D Lee; AM Fourie; Ying Wu; J Pang; Karen Ngo; PA Peterson; Klaus J Frueh; yang robin
Impaired immunoproteasome assembly and immune responses in PA28-/- mice.
Science (New York, N.Y.) 1999;286(5447):2162-5.
1999: K J Lee; Ana Angulo; Peter Ghazal; Kim D Janda
Soluble-polymer supported synthesis of a prostanoid library: identification of antiviral activity.
Organic letters 1999;1(11):1859-62.
1999: Liliane A Dickinson; JW Trauger; Eldon E Baird; Peter Ghazal; Peter B Dervan; Joel M Gottesfeld
Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides.
Biochemistry 1999;38(33):10801-7.
1999: J Chambers; Ana Angulo; D Amaratunga; Hongqing Guo; Y Jiang; JS Wan; Anton Bittner; Klaus J Frueh; MR Jackson; PA Peterson; Mark G Erlander; Peter Ghazal
DNA microarrays of the complex human cytomegalovirus genome: profiling kinetic class with drug sensitivity of viral gene expression.
Journal of virology 1999;73(7):5757-66.
1999: S Redpath; Ana Angulo; Nicholas R J Gascoigne; Peter Ghazal
Murine cytomegalovirus infection down-regulates MHC class II expression on macrophages by induction of IL-10.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6701-7.
1999: P Kanakaraj; Karen Ngo; Ying Wu; Ana Angulo; Peter Ghazal; CA Harris; John Siekierka; PA Peterson; Wai-Ping Fung-Leung
Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice.
The Journal of experimental medicine 1999;189(7):1129-38.
1998: Ana Angulo; Martin Messerle; U H Koszinowski; Peter Ghazal
Enhancer requirement for murine cytomegalovirus growth and genetic complementation by the human cytomegalovirus enhancer.
Journal of virology 1998;72(11):8502-9.
1998: Ana Angulo; R A Chandraratna; J F LeBlanc; Peter Ghazal
Ligand induction of retinoic acid receptors alters an acute infection by murine cytomegalovirus.
Journal of virology 1998;72(6):4589-600.
1998: J F LeBlanc; K E McLane; Paul W H I Parren; Dennis R Burton; Peter Ghazal
Recognition properties of a sequence-specific DNA binding antibody.
Biochemistry 1998;37(17):6015-22.
1996: K Ahn; Ana Angulo; Peter Ghazal; PA Peterson; Y Yang; Klaus J Frueh
Human cytomegalovirus inhibits antigen presentation by a sequential multistep process.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):10990-5.
1996: Ana Angulo; C Suto; Richard A Heyman; Peter Ghazal
Characterization of the sequences of the human cytomegalovirus enhancer that mediate differential regulation by natural and synthetic retinoids.
Molecular endocrinology (Baltimore, Md.) 1996;10(7):781-93.
1996: J F Baskar; Patsy P Smith; Gary Ciment; S Hoffmann; C Tucker; D J Tenney; A M Colberg-Poley; Jay A Nelson; Peter Ghazal
Developmental analysis of the cytomegalovirus enhancer in transgenic animals.
Journal of virology 1996;70(5):3215-26.
1996: J F Baskar; Patsy P Smith; G Nilaver; R A Jupp; S Hoffmann; N J Peffer; D J Tenney; A M Colberg-Poley; Peter Ghazal; Jay A Nelson
The enhancer domain of the human cytomegalovirus major immediate-early promoter determines cell type-specific expression in transgenic mice.
Journal of virology 1996;70(5):3207-14.
1996: G Lee; J Wu; P Luu; Peter Ghazal; O Flores
Inhibition of the association of RNA polymerase II with the preinitiation complex by a viral transcriptional repressor.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(6):2570-5.
1995: Ana Angulo; C Suto; Marcus F Boehm; Richard A Heyman; Peter Ghazal
Retinoid activation of retinoic acid receptors but not of retinoid X receptors promotes cellular differentiation and replication of human cytomegalovirus in embryonal cells.
Journal of virology 1995;69(6):3831-7.
1995: K E McLane; Dennis R Burton; Peter Ghazal
Transplantation of a 17-amino acid alpha-helical DNA-binding domain into an antibody molecule confers sequence-dependent DNA recognition.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):5214-8.
1995: Ana Angulo; Peter Ghazal
Regulation of human cytomegalovirus by retinoic acid.
Scandinavian journal of infectious diseases. Supplementum 1995;99():113-5.
1994: Ashlee V Moses; C Ibanez; R Gaynor; Peter Ghazal; Jay A Nelson
Differential role of long terminal repeat control elements for the regulation of basal and Tat-mediated transcription of the human immunodeficiency virus in stimulated and unstimulated primary human macrophages.
Journal of virology 1994;68(1):298-307.
1993: J Wu; R Jupp; Richard M Stenberg; Jay A Nelson; Peter Ghazal
Site-specific inhibition of RNA polymerase II preinitiation complex assembly by human cytomegalovirus IE86 protein.
Journal of virology 1993;67(12):7547-55.
1993: R Jupp; S Hoffmann; Richard M Stenberg; Jay A Nelson; Peter Ghazal
Human cytomegalovirus IE86 protein interacts with promoter-bound TATA-binding protein via a specific region distinct from the autorepression domain.
Journal of virology 1993;67(12):7539-46.
1993: R Jupp; S Hoffmann; A Depto; Richard M Stenberg; Peter Ghazal; Jay A Nelson
Direct interaction of the human cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box.
Journal of virology 1993;67(9):5595-604.
1993: R Jupp; O Flores; Jay A Nelson; Peter Ghazal
The DNA-binding subunit of human transcription factor IID can interact with the TATA box as a multimer.
The Journal of biological chemistry 1993;268(22):16105-8.
1992: Peter Ghazal; C DeMattei; E Giulietti; Steven A Kliewer; Kazuhiko Umesono; Ronald M Evans
Retinoic acid receptors initiate induction of the cytomegalovirus enhancer in embryonal cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7630-4.
1992: E Baracchini; E Glezer; K Fish; Richard M Stenberg; Jay A Nelson; Peter Ghazal
An isoform variant of the cytomegalovirus immediate-early auto repressor functions as a transcriptional activator.
Virology 1992;188(2):518-29.
1991: Peter Ghazal; J Young; E Giulietti; C DeMattei; J Garcia; R Gaynor; Richard M Stenberg; Jay A Nelson
A discrete cis element in the human immunodeficiency virus long terminal repeat mediates synergistic trans activation by cytomegalovirus immediate-early proteins.
Journal of virology 1991;65(12):6735-42.
1991: C E Ibanez; R Schrier; Peter Ghazal; C Wiley; Jay A Nelson
Human cytomegalovirus productively infects primary differentiated macrophages.
Journal of virology 1991;65(12):6581-8.
1990: Richard M Stenberg; J Fortney; S W Barlow; B P Magrane; Jay A Nelson; Peter Ghazal
Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains.
Journal of virology 1990;64(4):1556-65.