FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Roberto Gherzi

Research Profile

Chemicals & Drugs

Concepts & Ideas

Anatomy

Phenomena

Phosphorylation

Physiology

Living Beings

Mouse
Rats

Genes & Molecular Sequences

Amino Acid Sequences

Co-author Network

Publications

TOP 3
Matteo Giovarelli; Michela Pasero; Gabriele Bucci; Roberto Gherzi; Paola Briata
KSRP silencing favors neural differentiation of P19 teratocarcinoma cells.
Giuseppe Nicastro; Paola Briata; María Flor García-Mayoral; Roberto Gherzi; David Hollingworth; Geoff Kelly; Stephen R Martin; Andres Ramos
Noncanonical G recognition mediates KSRP regulation of let-7 biogenesis.
Michela Pasero; gabriele bucci; Roberto Gherzi; Matteo Giovarelli; Paola Briata
Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Roberto Gherzi (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Matteo Giovarelli; Michela Pasero; Gabriele Bucci; Roberto Gherzi; Paola Briata
KSRP silencing favors neural differentiation of P19 teratocarcinoma cells.
Biochimica et biophysica acta 2013;1829(5):469-79.
2012: Giuseppe Nicastro; Paola Briata; María Flor García-Mayoral; Roberto Gherzi; David Hollingworth; Geoff Kelly; Stephen R Martin; Andres Ramos
Noncanonical G recognition mediates KSRP regulation of let-7 biogenesis.
Nature structural & molecular biology 2012;19(12):1282-6.
2012: Michela Pasero; gabriele bucci; Roberto Gherzi; Matteo Giovarelli; Paola Briata
Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation.
Cell reports 2012;2(5):1159-68.
2012: David Hollingworth; Stephen R Martin; Giuseppe Nicastro; Paola Briata; Adela M Candel; Roberto Gherzi; Andres Ramos
KH domains with impaired nucleic acid binding as a tool for functional analysis.
Nucleic acids research 2012;40(14):6873-86.
2012: Paola David; Maddalena Brustia; Doriana Chiarinotti; Andreana De Mauri; Roberto Gherzi; C Navino; Elisabetta Tarrano; Martino De Leo
[Human papillomavirus infection and cervical intraepithelial neoplasia in dialyzed patients].
Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia 2012;29(2):205-9.
2012: Paola Briata; C-Y Chen; C-F Chou; M Giovarelli; W-J Lin; M Pasero; M G Rosenfeld; M Trabucchi; Roberto Gherzi
PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis.
Cell death and differentiation 2012;19(3):478-87.
2012: Emanuela Repetto; Michael G Rosenfeld; Paola Briata; Roberto Gherzi; Brian D Harfe; Nathalie Kuziner; Michael McManus; Michele Trabucchi
Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP.
PLoS genetics 2012;8(7):e1002823.
2011: Wei-Jye Lin; Ming Luo; Jacqueline N Parker; Tim M Townes; Jun Tsao; Xiaojia Zheng; Xiaolin Zhu; James J Cody; Jennifer M Coleman; Roberto Gherzi; Chen-Chung Lin; Ching-Yi Chen
Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection.
Molecular and cellular biology 2011;31(16):3196-207.
2011: Paola Briata; Ching-Yi Chen; Matteo Giovarelli; Michela Pasero; Michele Trabucchi; Andres Ramos; Roberto Gherzi
KSRP, many functions for a single protein.
Frontiers in bioscience : a journal and virtual library 2011;16():1787-96.
2010: Roberto Gherzi; Andres Ramos; Michele Trabucchi; Ching-Yi Chen; Paola Briata
The role of KSRP in mRNA decay and microRNA precursor maturation.
Wiley interdisciplinary reviews. RNA 2010;1(2):230-9.
2010: Irene Díaz-Moreno; David Hollingworth; Geoff Kelly; Stephen Martin; MaríaFlor García-Mayoral; Paola Briata; Roberto Gherzi; Andres Ramos
Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets.
Nucleic acids research 2010;38(15):5193-205.
2010: Roberto Gherzi; M Trabucchi; Marco Ponassi; I-E Gallouzi; M G Rosenfeld; Paola Briata
Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation.
Cell death and differentiation 2010;17(6):975-83.
2010: Michele Trabucchi; Paola Briata; Witold Filipowicz; Andres Ramos; Roberto Gherzi; Michael G Rosenfeld
KSRP promotes the maturation of a group of miRNA precursors.
Advances in experimental medicine and biology 2010;700():36-42.
2009: Michele Trabucchi; Paola Briata; Witold Filipowicz; Michael G Rosenfeld; Andres Ramos; Roberto Gherzi
How to control miRNA maturation?
RNA biology 2009;6(5):536-40.
2009: Tina Ruggiero; Michele Trabucchi; Francesca De Santa; Simona Zupo; Brian D Harfe; Michael McManus; M Geoff Rosenfeld; Paola Briata; Roberto Gherzi
LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(9):2898-908.
2009: Michele Trabucchi; Paola Briata; Mariaflor Garcia-Mayoral; Astrid D Haase; Witold Filipowicz; Andres Ramos; Roberto Gherzi; Michael G Rosenfeld
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs.
Nature 2009;459(7249):1010-4.
2009: Irene Díaz-Moreno; David Hollingworth; Thomas A Frenkiel; Geoff Kelly; Stephen Martin; Steven Howell; MaríaFlor García-Mayoral; Roberto Gherzi; Paola Briata; Andres Ramos
Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding.
Nature structural & molecular biology 2009;16(3):238-46.
2009: Morris Nechama; Yong Peng; Osnat Bell; Paola Briata; Roberto Gherzi; Daniel R Schoenberg; Tally Naveh-Many
KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells.
BMC cell biology 2009;10():70.
2008: Morris Nechama; Iddo Z Ben-Dov; Paola Briata; Roberto Gherzi; Tally Naveh-Many
The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(10):3458-68.
2007: María Flor García-Mayoral; David Hollingworth; Laura Masino; Irene Díaz-Moreno; Geoff Kelly; Roberto Gherzi; Chu-Fang Chou; Ching-Yi Chen; Andres Ramos
The structure of the C-terminal KH domains of KSRP reveals a noncanonical motif important for mRNA degradation.
Structure (London, England : 1993) 2007;15(4):485-98.
2007: Annamaria Bevilacqua; Laura Ghisolfi; Sara Franzi; Giovanna Maresca; Roberto Gherzi; Sergio Capaccioli; Angelo Nicolin; Gianfranco Canti
Stabilization of cellular mRNAs and up-regulation of proteins by oligoribonucleotides homologous to the Bcl2 adenine-uridine rich element motif.
Molecular pharmacology 2007;71(2):531-8.
2007: Tina Ruggiero; Michele Trabucchi; Marco Ponassi; Giorgio Corte; Ching-Yi Chen; Latifa al-Haj; Khalid S A Khabar; Paola Briata; Roberto Gherzi
Identification of a set of KSRP target transcripts upregulated by PI3K-AKT signaling.
BMC molecular biology 2007;8():28.
2006: Roberto Gherzi; Michele Trabucchi; Marco Ponassi; Tina Ruggiero; Giorgio Corte; Christoph Moroni; Ching-Yi Chen; Khalid S A Khabar; Jens S Andersen; Paola Briata
The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling.
PLoS biology 2006;5(1):e5.
2006: Chu-Fang Chou; Alok Mulky; Sushmit Maitra; Wei-Jye Lin; Roberto Gherzi; John C Kappes; Ching-Yi Chen
Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay.
Molecular and cellular biology 2006;26(10):3695-706.
2005: Paola Briata; Sonia Vanina Forcales; Marco Ponassi; Giorgio Corte; Ching-Yi Chen; Michael Karin; Pier Lorenzo Puri; Roberto Gherzi
p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts.
Molecular cell 2005;20(6):891-903.
2004: Martin Schmidlin; Min Lu; Sabrina A Leuenberger; Georg Stoecklin; Michel Mallaun; Brigitte Gross; Roberto Gherzi; daniel Hess; Brian A Hemmings; Christoph Moroni
The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B.
The EMBO journal 2004;23(24):4760-9.
2004: Roberto Gherzi; Kyung-Yeol Lee; Paola Briata; Daniel Wegmüller; Christoph Moroni; Michael Karin; Ching-Yi Chen
A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery.
Molecular cell 2004;14(5):571-83.
2003: Paola Briata; Cristina Ilengo; Giorgio Corte; Christoph Moroni; Michael G Rosenfeld; Ching-Yi Chen; Roberto Gherzi
The Wnt/beta-catenin-->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs.
Molecular cell 2003;12(5):1201-11.
2003: Annamaria Bevilacqua; Michela Ceriani; Gianfranco Canti; Laura Asnaghi; Roberto Gherzi; Gary Brewer; Laura Papucci; Nicola Schiavone; Sergio Capaccioli; Angelo Nicolin
Bcl-2 protein is required for the adenine/uridine-rich element (ARE)-dependent degradation of its own messenger.
The Journal of biological chemistry 2003;278(26):23451-9.
2001: C Y Chen; Roberto Gherzi; Shao-En Ong; E L Chan; Reinout Raijmakers; G J Pruijn; Georg Stoecklin; Christoph Moroni; M Mann; Michael Karin
AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.
Cell 2001;107(4):451-64.
2000: C Y Chen; Roberto Gherzi; J S Andersen; Guido Gaietta; Karsten Jürchott; hans-dieter royer; M Mann; Michael Karin
Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation.
Genes & development 2000;14(10):1236-48.
1998: Roberto Gherzi; Alessandra Leprini; Annalisa Siri; Luciano Zardi
Structure of 5' region of human tenascin-R gene and characterization of its promoter.
DNA and cell biology 1998;17(3):275-82.
1998: Roberto Gherzi; C Bellini; E Bonioli
Altered response to stimuli of the AP-1/DNA binding activity in a syndrome of precocious ageing (geroderma osteodysplastica hereditaria).
Mechanisms of ageing and development 1998;100(2):169-75.
1998: Alessandra Leprini; Roberto Gherzi; E Vecchi; Laura Borsi; Luciano Zardi; Annalisa Siri
Rat tenascin-R gene: structure, chromosome location and transcriptional activity of promoter and exon 1.
Cytogenetics and cell genetics 1998;83(1-2):115-23.
1997: Roberto Gherzi; Paola Briata; Edoardo Boncinelli; Marco Ponassi; G Querzè; Francesca Viti; Giorgio Corte; Luciano Zardi
The human homeodomain protein OTX2 binds to the human tenascin-C promoter and trans-represses its activity in transfected cells.
DNA and cell biology 1997;16(5):559-67.
1997: Giulia Arrigo; Roberto Gherzi; Maria Clara Bonaglia; Alessandra Leprini; Orsetta Zuffardi; Luciano Zardi
Assignment of the tenascin-R gene (Tnr) to mouse chromosome 4 band E2 by fluorescence in situ hybridization; refinement of the human TNR location to chromosome 1q24.
Cytogenetics and cell genetics 1997;78(2):145-6.
1996: Alessandra Leprini; Roberto Gherzi; Annalisa Siri; G Querzé; F Viti; Luciano Zardi
The human tenascin-R gene.
The Journal of biological chemistry 1996;271(49):31251-4.
1995: Roberto Gherzi; Marco Ponassi; B Gaggero; Luciano Zardi
The first untranslated exon of the human tenascin-C gene plays a regulatory role in gene transcription.
FEBS letters 1995;369(2-3):335-9.
1995: Roberto Gherzi; Hans-Christoph Fehmann; A Volz; Marco Ponassi; Burkhard Göke
The glucagon gene is transcribed in beta-like pancreatic cells.
Experimental cell research 1995;218(2):460-8.
1995: Roberto Gherzi; Barbara Carnemolla; Annalisa Siri; Marco Ponassi; Enrica Balza; Luciano Zardi
Human tenascin gene. Structure of the 5'-region, identification, and characterization of the transcription regulatory sequences.
The Journal of biological chemistry 1995;270(7):3429-34.
1995: Hans-Christoph Fehmann; Roberto Gherzi; Burkhard Göke
Regulation of islet hormone gene expression by incretin hormones.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1995;103 Suppl 2():56-65.
1994: Roberto Gherzi; Paola Briata; Hans-Christoph Fehmann; Burkhard Göke
Ras antagonizes cAMP stimulated glucagon gene transcription in pancreatic islet cell lines.
FEBS letters 1994;353(3):277-80.
1994: Roberto Gherzi; Hans-Christoph Fehmann; Rolf Eissele; Burkhard Göke
Expression, intracellular localization, and gene transcription regulation of the secretory protein 7B2 in endocrine pancreatic cell lines and human insulinomas.
Experimental cell research 1994;213(1):20-7.
1993: Paola Briata; F D'Anna; A T Franzi; Roberto Gherzi
AP-1 activity during normal human keratinocyte differentiation: evidence for a cytosolic modulator of AP-1/DNA binding.
Experimental cell research 1993;204(1):136-46.
1993: Roberto Gherzi; Paola Briata
[Insulin receptors, mechanism of signal transduction. Examples of abnormalities in states of insulin resistance].
Journées annuelles de diabétologie de l'Hôtel-Dieu 1993;():11-21.
1992: Giorgio Sesti; MA Marini; Paola Briata; A N Tullio; A Montemurro; P Borboni; R De Pirro; Roberto Gherzi; Renato Lauro
Androgens increase insulin receptor mRNA levels, insulin binding, and insulin responsiveness in HEp-2 larynx carcinoma cells.
Molecular and cellular endocrinology 1992;86(1-2):111-8.
1992: Roberto Gherzi; B Sparatore; M Patrone; A Sciutto; Paola Briata
Protein kinase C mRNA levels and activity in reconstituted normal human epidermis: relationships to cell differentiation.
Biochemical and biophysical research communications 1992;184(1):283-91.
1992: Roberto Gherzi; Giovanni Melioli; Michele De Luca; A D'Agostino; G Distefano; M Guastella; F D'Anna; A T Franzi; Ranieri Cancedda
"HepG2/erythroid/brain" type glucose transporter (GLUT1) is highly expressed in human epidermis: keratinocyte differentiation affects GLUT1 levels in reconstituted epidermis.
Journal of cellular physiology 1992;150(3):463-74.
1991: Roberto Gherzi; Giovanni Melioli; Michele De Luca; A D'Agostino; M Guastella; Carlo E Traverso; F D'Anna; A T Franzi; Ranieri Cancedda
High expression levels of the "erythroid/brain" type glucose transporter (GLUT1) in the basal cells of human eye conjunctiva and oral mucosa reconstituted in culture.
Experimental cell research 1991;195(1):230-6.
1991: Paola Briata; C Bellini; Marina Vignolo; Roberto Gherzi
Insulin receptor gene expression is reduced in cells from a progeric patient.
Molecular and cellular endocrinology 1991;75(1):9-14.
1990: Paola Briata; Roberto Gherzi
Multifactorial control of insulin receptor gene expression in human cell lines.
Biochemical and biophysical research communications 1990;170(3):1184-90.
1990: Paola Briata; L Briata; Roberto Gherzi
Glucose starvation and glycosylation inhibitors reduce insulin receptor gene expression: characterization and potential mechanism in human cells.
Biochemical and biophysical research communications 1990;169(2):397-405.
1990: L Rossetti; Ralph DeFronzo; Roberto Gherzi; P Stein; G Andraghetti; G Falzetti; G I Shulman; E Klein-Robbenhaar; Renzo Cordera
Effect of metformin treatment on insulin action in diabetic rats: in vivo and in vitro correlations.
Metabolism: clinical and experimental 1990;39(4):425-35.
1989: Paola Briata; C Laurino; Roberto Gherzi
c-myc gene expression in human cells is controlled by glucose.
Biochemical and biophysical research communications 1989;165(3):1123-9.
1989: A Pessino; Roberto Gherzi; G Damiani; R Longhi; L Adezati; Renzo Cordera
Antipeptide antibodies toward the extracellular domain of insulin receptor beta-subunit.
Biochemical and biophysical research communications 1989;162(3):1236-43.
1989: Roberto Gherzi; Giorgio Sesti; G Andraghetti; R De Pirro; Renato Lauro; L Adezati; Renzo Cordera
An extracellular domain of the insulin receptor beta-subunit with regulatory function on protein-tyrosine kinase.
The Journal of biological chemistry 1989;264(15):8627-35.
1989: Paola Briata; Roberto Gherzi; L Adezati; Renzo Cordera
Effect of two different glucose concentrations on insulin receptor mRNA levels in human hepatoma HepG2 cells.
Biochemical and biophysical research communications 1989;160(3):1415-20.
1988: Roberto Gherzi; C Caratti; G Andraghetti; Stefano Bertolini; A Montemurro; Giorgio Sesti; Renzo Cordera
Direct modulation of insulin receptor protein tyrosine kinase by vanadate and anti-insulin receptor monoclonal antibodies.
Biochemical and biophysical research communications 1988;152(3):1474-80.
1987: Renzo Cordera; G Andraghetti; Roberto Gherzi; L Adezati; A Montemurro; Renato Lauro; I D Goldfine; R De Pirro
Species specificity of insulin binding and insulin receptor protein tyrosine kinase activity.
Endocrinology 1987;121(6):2007-10.
1987: Roberto Gherzi; Renzo Cordera; G Andraghetti; R De Pirro; G R Freidenberg; Renato Lauro; L Adezati
Regulation of insulin receptor-associated tyrosine kinase by a polyclonal IgG.
Molecular and cellular endocrinology 1987;53(1-2):9-14.
1986: Roberto Gherzi; G Andraghetti; E Ferrannini; Renzo Cordera
Insulin receptor autophosphorylation and kinase activity in streptozotocin diabetic rats. Effect of a short fast.
Biochemical and biophysical research communications 1986;140(3):850-6.
1986: Renzo Cordera; Roberto Gherzi; R De Pirro; G Andraghetti; G R Freidenberg; F Minuto; Renato Lauro; G Giordano; L Adezati
Insulin-like growth factor I (IGF I) receptor autophosphorylation and kinase activity. Effect of a human polyclonal antibody (pIgG)
Biochemical and biophysical research communications 1986;138(3):1023-9.
1986: Roberto Gherzi; G Andraghetti; Renzo Cordera; L Adezati
Porcine and human semisynthetic insulin bind equally to the insulin receptor on red blood cells.
Diabète & métabolisme 1986;12(4):225-6.
1986: Roberto Gherzi; G Andraghetti; G Versari; Renzo Cordera
Effect of insulin receptor autophosphorylation on insulin receptor binding.
Molecular and cellular endocrinology 1986;45(2-3):247-52.
1986: Renzo Cordera; Roberto Gherzi; R De Pirro; G Andraghetti
[Kinase activity associated with the insulin receptor: biochemical characterization].
Minerva endocrinologica 1986;11(2):107-10.
1985: Renzo Cordera; Roberto Gherzi; R De Pirro; L Rossetti; G R Freidenberg; G Andraghetti; Renato Lauro; L Adezati
Inhibition of insulin and epidermal growth factor (EGF) receptor autophosphorylation by a human polyclonal IgG.
Biochemical and biophysical research communications 1985;132(3):991-1000.
1985: Renzo Cordera; Stefano Bertolini; G Andraghetti; G Pistocchi; M de Alessi; Roberto Gherzi
Insulin receptor binding on red cells of hypertriglyceridemic patients. Effect of a low fat, low carbohydrate diet.
Diabète & métabolisme 1985;11(3):137-40.
1985: Renzo Cordera; G Andraghetti; R Bonadonna; Roberto Gherzi; M Maiello; P Odetti; G Viviani; F Berri; L Adezati
Influence of cell age and ketoaminic linkage on rapid glycosylation of hemoglobin in human red cells in vitro.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1985;17(4):201-4.
1985: Roberto Gherzi; G Andraghetti; L Adezati; Renzo Cordera
Insulin receptor regulation in human mature red cells in vitro.
Hormone research 1985;22(4):270-5.
1984: Renzo Cordera; G Chimini; M Bagnasco; Roberto Gherzi
Membrane degradation of receptor bound insulin. Influence of glipizide.
Minerva endocrinologica 1984;9(2):293-6.
1984: L Adezati; G Andraghetti; D Boeri; A Canepa; G Carta; Renzo Cordera; G Falzetti; Roberto Gherzi; M Maiello; P Odetti
[Human insulin. Receptor affinity, acute effects and long-term treatment].
Minerva endocrinologica 1984;9(2):181-92.
1984: Renzo Cordera; G Chimini; M Bagnasco; Roberto Gherzi
Insulin binding on MOLT 4 cells: effect of a sulfonylurea.
Hormone research 1984;20(4):246-51.