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François Ghiringhelli

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Anne-Sophie Pierre; Jerome Bellenger; S Bellenger; Cécile Fèvre; François Ghiringhelli; Joseph Gresti; Aziz Hichami; Mélaine Minville-Walz; Michel Narce; Laurent Pichon; Mickaël Rialland
Trans-10, cis-12 conjugated linoleic acid induced cell death in human colon cancer cells through reactive oxygen species-mediated ER stress.
Alice Hervieu; Cédric Rébé; Pierre Vabres; Frédérique Végran; Lionel Apetoh; Mélanie Bruchard; Fanny Chalmin; François Ghiringhelli; Grégoire Mignot
Dacarbazine-mediated upregulation of NKG2D ligands on tumor cells activates NK and CD8 T cells and restrains melanoma growth.
Mélanie Bruchard; Fanny Chalmin; Angélique Chevriaux; Jean-Louis Connat; Valentin Derangère; Jean Kanellopoulos; François Martin; Grégoire Mignot; Cédric Rébé; Bernhard RYFFEL; Benoit Simon; Frédérique Végran; Lionel Apetoh; Wilfrid Boireau; François Ghiringhelli
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.

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All Publications

2013: Anne-Sophie Pierre; Jerome Bellenger; S Bellenger; Cécile Fèvre; François Ghiringhelli; Joseph Gresti; Aziz Hichami; Mélaine Minville-Walz; Michel Narce; Laurent Pichon; Mickaël Rialland
Trans-10, cis-12 conjugated linoleic acid induced cell death in human colon cancer cells through reactive oxygen species-mediated ER stress.
Biochimica et biophysica acta 2013;1831(4):759-68.
2013: Alice Hervieu; Cédric Rébé; Pierre Vabres; Frédérique Végran; Lionel Apetoh; Mélanie Bruchard; Fanny Chalmin; François Ghiringhelli; Grégoire Mignot
Dacarbazine-mediated upregulation of NKG2D ligands on tumor cells activates NK and CD8 T cells and restrains melanoma growth.
The Journal of investigative dermatology 2013;133(2):499-508.
2013: Mélanie Bruchard; Fanny Chalmin; Angélique Chevriaux; Jean-Louis Connat; Valentin Derangère; Jean Kanellopoulos; François Martin; Grégoire Mignot; Cédric Rébé; Bernhard RYFFEL; Benoit Simon; Frédérique Végran; Lionel Apetoh; Wilfrid Boireau; François Ghiringhelli
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
Nature medicine 2013;19(1):57-64.
2012: François Martin; Lionel Apetoh; François Ghiringhelli
Controversies on the role of Th17 in cancer: a TGF-β-dependent immunosuppressive activity?
Trends in molecular medicine 2012;18(12):742-9.
2012: Sylvain Ladoire; C Levy; A Lortholary; C Mesleard; Grégoire Mignot; F Penault-Llorca; Cédric Rébé; H Roché; M Spielmann; Lionel Apetoh; Laurent Arnould; Romain Boidot; Franck bonnetain; A Chevriaux; Cécile Dalban; F Eichler; Pierre Fumoleau; François Ghiringhelli
FOXP3 expression in cancer cells and anthracyclines efficacy in patients with primary breast cancer treated with adjuvant chemotherapy in the phase III UNICANCER-PACS 01 trial.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2012;23(10):2552-61.
2012: Laurie Menger; Mickaël Michaud; Grégoire Mignot; Nazanine Modjtahedi; Frederic Schlemmer; Shensi Shen; Abdul Qader Sukkurwala; Eric Sulpice; Erika Vacchelli; Takahiro Yamazaki; Laurence Zitvogel; Sandy Adjemian; Fabrice André; Lorenzo Galluzzi; François Ghiringhelli; Xavier Gidrol; Oliver Kepp; Clara Locher; Yuting Ma; Isabelle Martins; Guido Kroemer
Cardiac glycosides exert anticancer effects by inducing immunogenic cell death.
Science translational medicine 2012;4(143):143ra99.
2012: Magali Terme; Evelyn Ullrich; Sophie Viaud; Hideo Yagita; Laetitia Aymeric; Nathalie Chaput; Lieping Chen; Jerome Coudert; Mariapia Degli-Esposti; Mélanie Desbois; François Ghiringhelli; Gilles Kaplanski; Masashi Kato; Guido Kroemer; Salaheddine Mécheri; Kathrin Meinhardt; Armelle Prévost-Blondel; Bernard Ryffel; Joachim L Schultze; Eric Tartour; Laurence Zitvogel
Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells.
Cancer research 2012;72(11):2757-67.
2012: Fanny Chalmin; Angélique Chevriaux; Valentin Derangère; Gerard Eberl; Lionel Apetoh; Christophe Borg; Mélanie Bruchard; Aziz Hichami; Sylvain Ladoire; David Masson; Grégoire Mignot; Jean René Pallandre; Cédric Rébé; Simon C Robson; Bernhard RYFFEL; Frédérique Végran; Julie Vincent; François Ghiringhelli
Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression.
Immunity 2012;36(3):362-73.
2012: François Ghiringhelli; Mélanie Bruchard; Fanny Chalmin; Cédric Rébé
Production of adenosine by ectonucleotidases: a key factor in tumor immunoescape.
Journal of biomedicine & biotechnology 2012;2012():473712.
2011: Johnny Moretto; Janice R Aldrich-Wright; Bruno Chauffert; François Ghiringhelli; Florence Bouyer
Discrepancy between in vitro and in vivo antitumor effect of a new platinum(II) metallointercalator.
Investigational new drugs 2011;29(6):1164-76.
2011: Mathieu Boulin; Jean-Pierre Cercueil; Bruno Chauffert; Philippe Fagnoni; François Ghiringhelli; Serge Aho; Laurent Bedenne; Séverine Guiu; Patrick Hillon; Denis Krause; Boris Guiu
Screening of anticancer drugs for chemoembolization of hepatocellular carcinoma.
Anti-cancer drugs 2011;22(8):741-8.
2011: Sylvain Ladoire; Pierre Pfitzenmeyer; Valérie Quipourt; Laurie Rambach; Laurent Arnould; Laure Favier; Pierre Fumoleau; François Ghiringhelli; Bruno Coudert
Feasibility and safety of weekly sequential epirubicin-paclitaxel as adjuvant treatment for operable breast cancer patients older than 70 years.
Clinical breast cancer 2011;11(4):235-40.
2011: Sylvain Ladoire; F Martin; Grégoire Mignot; Cédric Rébé; Lionel Apetoh; Laurent Arnould; Bruno Coudert; Pierre Fumoleau; François Ghiringhelli
T-bet expression in intratumoral lymphoid structures after neoadjuvant trastuzumab plus docetaxel for HER2-overexpressing breast carcinoma predicts survival.
British journal of cancer 2011;105(3):366-71.
2011: Sylvain Ladoire; François Martin; François Ghiringhelli
Prognostic role of FOXP3+ regulatory T cells infiltrating human carcinomas: the paradox of colorectal cancer.
Cancer immunology, immunotherapy : CII 2011;60(7):909-18.
2011: Sylvain Ladoire; Francois Martin; Grégoire Mignot; Cédric Rébé; André Vanoli; Lionel Apetoh; Laurent Arnould; Marie Hélène Bizollon; Franck bonnetain; Bruno Coudert; Charles Coutant; Sandrine Dabakuyo; Pierre Fumoleau; François Ghiringhelli
In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival.
The Journal of pathology 2011;224(3):389-400.
2011: Yuting Ma; Laetitia Aymeric; Clara Locher; Stephen R Mattarollo; Nicolas F Delahaye; Pablo Pereira; Laurent Boucontet; Lionel Apetoh; François Ghiringhelli; Noelia Casares; Juan José Lasarte; Goro Matsuzaki; Koichi Ikuta; Bernard Ryffel; Kamel Benlagha; Antoine Tesnière; Nicolas Ibrahim; Julie Déchanet-Merville; Nathalie Chaput; Mark J Smyth; Guido Kroemer; Laurence Zitvogel
Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy.
The Journal of experimental medicine 2011;208(3):491-503.
2011: Grégoire Mignot; Fanny Chalmin; Sylvain Ladoire; Cédric Rébé; François Ghiringhelli
Tumor exosome-mediated MDSC activation.
The American journal of pathology 2011;178(3):1403-4; author reply 1404-5.
2011: Lionel Apetoh; Clara Locher; François Ghiringhelli; Guido Kroemer; Laurence Zitvogel
Harnessing dendritic cells in cancer.
Seminars in immunology 2011;23(1):42-9.
2011: Dominique Delmas; Virginie Aires; Emeric Limagne; Patrick Dutartre; Frédéric Mazué; François Ghiringhelli; Norbert Latruffe
Transport, stability, and biological activity of resveratrol.
Annals of the New York Academy of Sciences 2011;1215():48-59.
2011: Olivier Facy; François Radais; Sylvain Ladoire; Delphine Delroeux; Hervé Tixier; François Ghiringhelli; Patrick Rat; Bruno Chauffert; Pablo Ortega Deballon
Comparison of hyperthermia and adrenaline to enhance the intratumoral accumulation of cisplatin in a murine model of peritoneal carcinomatosis.
Journal of experimental & clinical cancer research : CR 2011;30():4.
2011: Sylvain Ladoire; Franck bonnetain; Mélanie Gauthier; Sylvie Zanetta; Jean Michel Petit; Séverine Guiu; Isabelle Kermarrec; Eric Mourey; Frederic Michel; Denis Krause; Patrick Hillon; Luc Cormier; François Ghiringhelli; Boris Guiu
Visceral fat area as a new independent predictive factor of survival in patients with metastatic renal cell carcinoma treated with antiangiogenic agents.
The oncologist 2011;16(1):71-81.
2011: Sylvain Ladoire; Laurent Arnould; Grégoire Mignot; Bruno Coudert; Cédric Rébé; Fanny Chalmin; Julie Vincent; Mélanie Bruchard; Bruno Chauffert; François Martin; Pierre Fumoleau; François Ghiringhelli
Presence of Foxp3 expression in tumor cells predicts better survival in HER2-overexpressing breast cancer patients treated with neoadjuvant chemotherapy.
Breast cancer research and treatment 2011;125(1):65-72.
2010: Sylvain Ladoire; Jean Christophe Eymard; Sylvie Zanetta; Grégoire Mignot; Etienne Martin; Isabelle Kermarrec; Eric Mourey; Frédéric Michel; Luc Cormier; François Ghiringhelli
Metronomic oral cyclophosphamide prednisolone chemotherapy is an effective treatment for metastatic hormone-refractory prostate cancer after docetaxel failure.
Anticancer research 2010;30(10):4317-23.
2010: Clara Locher; R Conforti; Laetitia Aymeric; Yuting Ma; Takahiro Yamazaki; Sylvie Rusakiewicz; Antoine Tesnière; François Ghiringhelli; Lionel Apetoh; Yannis Morel; Jean-Philippe Girard; Guido Kroemer; Laurence Zitvogel
Desirable cell death during anticancer chemotherapy.
Annals of the New York Academy of Sciences 2010;1209():99-108.
2010: Sylvain Ladoire; Caroline Beynat; Pierre Diaz; Bruno Coudert; Laure Favier; François Ghiringhelli
Spontaneous pyopneumothorax in patients treated with mTOR inhibitors for subpleural pulmonary metastases.
Medical oncology (Northwood, London, England) 2010;27(3):938-41.
2010: François Martin; Sylvain Ladoire; G Mignot; Lionel Apetoh; François Ghiringhelli
Human FOXP3 and cancer.
Oncogene 2010;29(29):4121-9.
2010: Cedric Khouri; Boris Guiu; Jean-Pierre Cercueil; Bruno Chauffert; Sylvain Ladoire; François Ghiringhelli
Raltitrexed and oxaliplatin hepatic arterial infusion for advanced colorectal cancer: a retrospective study.
Anti-cancer drugs 2010;21(6):656-61.
2010: Fanny Chalmin; Grégoire Mignot; François Ghiringhelli
[Myeloid-derived suppressor cells: a key player in cancer].
Médecine sciences : M/S 2010;26(6-7):576-9.
2010: Yuting Ma; Oliver Kepp; François Ghiringhelli; Lionel Apetoh; Laetitia Aymeric; Clara Locher; Antoine Tesniere; Isabelle Martins; André Ly; Nicole M Haynes; Mark J Smyth; Guido Kroemer; Laurence Zitvogel
Chemotherapy and radiotherapy: cryptic anticancer vaccines.
Seminars in immunology 2010;22(3):113-24.
2010: Julie Vincent; Grégoire Mignot; Fanny Chalmin; Sylvain Ladoire; Mélanie Bruchard; Angélique Chevriaux; François Martin; Lionel Apetoh; Cédric Rébé; François Ghiringhelli
5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity.
Cancer research 2010;70(8):3052-61.
2010: Boris Guiu; Julie Vincent; Séverine Guiu; Sylvain Ladoire; Pablo Ortega Deballon; Jean-Pierre Cercueil; Bruno Chauffert; François Ghiringhelli
Hepatic arterial infusion of gemcitabine-oxaliplatin in a large metastasis from colon cancer.
World journal of gastroenterology : WJG 2010;16(9):1150-4.
2010: Boris Guiu; Jean Michel Petit; Franck bonnetain; Sylvain Ladoire; Séverine Guiu; Jean-Pierre Cercueil; Denis Krausé; Patrick Hillon; Christophe Borg; Bruno Chauffert; François Ghiringhelli
Visceral fat area is an independent predictive biomarker of outcome after first-line bevacizumab-based treatment in metastatic colorectal cancer.
Gut 2010;59(3):341-7.
2010: Fanny Chalmin; Sylvain Ladoire; Grégoire Mignot; Julie Vincent; Mélanie Bruchard; Jean-Paul Remy-Martin; Wilfrid Boireau; Alain Rouleau; Benoit Simon; David Lanneau; Aurélie de Thonel; Gabriele Multhoff; Arlette Hamman; François Martin; Bruno Chauffert; Eric Solary; Laurence Zitvogel; Carmen Garrido; Bernhard RYFFEL; Christophe Borg; Lionel Apetoh; Cédric Rébé; François Ghiringhelli
Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.
The Journal of clinical investigation 2010;120(2):457-71.
2010: Laetitia Aymeric; Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; Isabelle Martins; Guido Kroemer; Mark J Smyth; Laurence Zitvogel
Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity.
Cancer research 2010;70(3):855-8.
2010: Antoine Tesniere; F Schlemmer; V Boige; O Kepp; I Martins; François Ghiringhelli; L Aymeric; M Michaud; Lionel Apetoh; L Barault; J Mendiboure; J-P Pignon; V Jooste; Peter van Endert; M Ducreux; Laurence Zitvogel; F Piard; Guido Kroemer
Immunogenic death of colon cancer cells treated with oxaliplatin.
Oncogene 2010;29(4):482-91.
2009: Clara Locher; Sylvie Rusakiewicz; Antoine Tesnière; François Ghiringhelli; Lionel Apetoh; Guido Kroemer; Laurence Zitvogel
Witch hunt against tumor cells enhanced by dendritic cells.
Annals of the New York Academy of Sciences 2009;1174():51-60.
2008: Laurence Zitvogel; Antoine Tesniere; Lionel Apetoh; François Ghiringhelli; Guido Kroemer
[Immunological aspects of anticancer chemotherapy].
Bulletin de l'Académie nationale de médecine 2008;192(7):1469-87; discussion 1487-9.
2008: Antoine Tesniere; Lionel Apetoh; François Ghiringhelli; Nicholas Joza; Theocharis Panaretakis; Oliver Kepp; Frederic Schlemmer; Laurence Zitvogel; Guido Kroemer
Immunogenic cancer cell death: a key-lock paradigm.
Current opinion in immunology 2008;20(5):504-11.
2008: Cédric Ménard; François Ghiringhelli; Stephan Roux; Nathalie Chaput; Christine Mateus; Ursula Grohmann; Sophie Caillat-Zucman; Laurence Zitvogel; Caroline Robert
Ctla-4 blockade confers lymphocyte resistance to regulatory T-cells in advanced melanoma: surrogate marker of efficacy of tremelimumab?
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(16):5242-9.
2008: Laurence Zitvogel; Lionel Apetoh; François Ghiringhelli; Fabrice André; Antoine Tesniere; Guido Kroemer
The anticancer immune response: indispensable for therapeutic success?
The Journal of clinical investigation 2008;118(6):1991-2001.
2008: Lionel Apetoh; Antoine Tesniere; François Ghiringhelli; Guido Kroemer; Laurence Zitvogel
Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies.
Cancer research 2008;68(11):4026-30.
2008: Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; M Obeid; Grégoire Mignot; Evelyn Ullrich; Guido Kroemer; Laurence Zitvogel
Cancer is not just a disease of a tissue: it is a host disease. How to reactivate host defense against tumors using conventional therapies of cancer?
Annales d'endocrinologie 2008;69(2):151-2.
2008: Laurence Zitvogel; Lionel Apetoh; François Ghiringhelli; Guido Kroemer
Immunological aspects of cancer chemotherapy.
Nature reviews. Immunology 2008;8(1):59-73.
2008: Antoine Tesniere; Theocharis Panaretakis; O Kepp; Lionel Apetoh; François Ghiringhelli; Laurence Zitvogel; Guido Kroemer
Molecular characteristics of immunogenic cancer cell death.
Cell death and differentiation 2008;15(1):3-12.
2007: Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; Alfredo Criollo; Carla Ortiz; Rosette Lidereau; Christophe Mariette; Nathalie Chaput; Jean-Paul Mira; Suzette Delaloge; Fabrice André; Thomas Tursz; Guido Kroemer; Laurence Zitvogel
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy.
Immunological reviews 2007;220():47-59.
2007: Michel Obeid; Antoine Tesniere; Theocharis Panaretakis; Roberta Tufi; Nick Joza; Peter van Endert; François Ghiringhelli; Lionel Apetoh; Nathalie Chaput; Caroline Flament; Evelyn Ullrich; Stéphane de Botton; Laurence Zitvogel; Guido Kroemer
Ecto-calreticulin in immunogenic chemotherapy.
Immunological reviews 2007;220():22-34.
2007: Nathalie Chaput; Stéphane de Botton; Michel Obeid; Lionel Apetoh; François Ghiringhelli; Theocharis Panaretakis; Caroline Flament; Laurence Zitvogel; Guido Kroemer
Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference.
Journal of molecular medicine (Berlin, Germany) 2007;85(10):1069-76.
2007: Michel Obeid; Theocharis Panaretakis; Antoine Tesniere; Nick Joza; Roberta Tufi; Lionel Apetoh; François Ghiringhelli; Laurence Zitvogel; Guido Kroemer
Leveraging the immune system during chemotherapy: moving calreticulin to the cell surface converts apoptotic death from "silent" to immunogenic.
Cancer research 2007;67(17):7941-4.
2007: Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; Michel Obeid; Carla Ortiz; Alfredo Criollo; Grégoire Mignot; M Chiara Maiuri; Evelyn Ullrich; Patrick Saulnier; Huan Yang; Sebastian Amigorena; Bernhard RYFFEL; Franck J Barrat; Paul Saftig; Francis Levi; Rosette Lidereau; Catherine Nogues; Jean-Paul Mira; Agnès Chompret; Virginie Joulin; Françoise Clavel-Chapelon; Jean Bourhis; Fabrice André; Suzette Delaloge; Thomas Tursz; Guido Kroemer; Laurence Zitvogel
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.
Nature medicine 2007;13(9):1050-9.
2007: N Falvo; François Ghiringhelli; Sabine Berthier; Bernard Bonnotte; Bernard Lorcerie
[Case-control study evaluating the incidence of hyperhomocysteinemia in cancer patients in an internal medicine department].
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne 2007;28(8):520-5.
2007: François Ghiringhelli; Cedric Menard; Pierre-Emmanuel Puig; Sylvain Ladoire; Stephan Roux; François Martin; Eric Solary; Axel Le Cesne; Laurence Zitvogel; Bruno Chauffert
Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients.
Cancer immunology, immunotherapy : CII 2007;56(5):641-8.
2007: François Ghiringhelli; Lionel Apetoh; Franck Housseau; Guido Kroemer; Laurence Zitvogel
Links between innate and cognate tumor immunity.
Current opinion in immunology 2007;19(2):224-31.
2007: Lionel Apetoh; Michel Obeid; Antoine Tesniere; François Ghiringhelli; Gian Maria Fimia; Mauro Piacentini; Guido Kroemer; Laurence Zitvogel
Immunogenic chemotherapy: discovery of a critical protein through proteomic analyses of tumor cells.
Cancer genomics & proteomics 2007;4(2):65-70.
2007: Lionel Apetoh; François Ghiringhelli; Laurence Zitvogel
[Calreticulin dictates the immunogenicity of anti-cancer chemotherapy and radiotherapy].
Médecine sciences : M/S 2007;23(3):257-8.
2007: Michel Obeid; Antoine Tesniere; François Ghiringhelli; Gian Maria Fimia; Lionel Apetoh; Jean-Luc PERFETTINI; Maria Castedo; Grégoire Mignot; Theocharis Panaretakis; Noelia Casares; Didier Métivier; Nathanael Larochette; Peter van Endert; Fabiola Ciccosanti; Mauro Piacentini; Laurence Zitvogel; Guido Kroemer
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Nature medicine 2007;13(1):54-61.
2006: François Ghiringhelli; Cédric Ménard; Francois Martin; Laurence Zitvogel
The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression.
Immunological reviews 2006;214():229-38.
2006: Elise Schmitt; Loic Maingret; Pierre-Emmanuel Puig; Anne-Laure Rerole; François Ghiringhelli; Arlette Hammann; Eric Solary; Guido Kroemer; Carmen Garrido
Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma.
Cancer research 2006;66(8):4191-7.
2006: Julien Taieb; Nathalie Chaput; Noël Emile Célestin Schartz; Stéphan Roux; Sophie Novault; Cédric Ménard; François Ghiringhelli; Magali Terme; Antoine F Carpentier; Guillaume Darrasse-Jèze; Guillaume Darrasse-Jèse; François Lemonnier; Laurence Zitvogel
Chemoimmunotherapy of tumors: cyclophosphamide synergizes with exosome based vaccines.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):2722-9.
2006: François Ghiringhelli; Laurence Zitvogel
[Vaccine strategies against melanoma].
Médecine sciences : M/S 2006;22(2):183-7.
2006: Julien Taieb; Nathalie Chaput; Cédric Ménard; Lionel Apetoh; Evelyn Ullrich; Mathieu Bonmort; Marie Péquignot; Noelia Casares; Magali Terme; Caroline Flament; Paule Opolon; Yann Lecluse; Didier Métivier; Elena Tomasello; Eric Vivier; François Ghiringhelli; François Martin; David Klatzmann; Thierry Poynard; Thomas Tursz; Graça Raposo; Hideo Yagita; Bernard Ryffel; Guido Kroemer; Laurence Zitvogel
A novel dendritic cell subset involved in tumor immunosurveillance.
Nature medicine 2006;12(2):214-9.
2005: Noelia Casares; Marie O Pequignot; Antoine Tesniere; François Ghiringhelli; Stéphan Roux; Nathalie Chaput; Elise Schmitt; Ahmed Hamai; Sandra Hervas-Stubbs; Michel Obeid; Frédéric Coutant; Didier Métivier; Evelyne Pichard; Pierre Aucouturier; Gérard Pierron; Carmen Garrido; Laurence Zitvogel; Guido Kroemer
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death.
The Journal of experimental medicine 2005;202(12):1691-701.
2005: François Ghiringhelli; Cédric Ménard; Magali Terme; Caroline Flament; Julien Taieb; Nathalie Chaput; Pierre-Emmanuel Puig; Sophie Novault; Bernard Escudier; Eric Vivier; Axel Lecesne; Caroline Robert; Jean-Yves Blay; Jacky Bernard; Sophie Caillat-Zucman; Antonio Freitas; Thomas Tursz; Orianne Wagner-Ballon; Claude Capron; William Vainchencker; François Martin; Laurence Zitvogel
CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner.
The Journal of experimental medicine 2005;202(8):1075-85.
2005: François Ghiringhelli; Pierre-Emmanuel Puig; Stephan Roux; Arnaud Parcellier; Elise Schmitt; Eric Solary; Guido Kroemer; François Martin; Bruno Chauffert; Laurence Zitvogel
Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation.
The Journal of experimental medicine 2005;202(7):919-29.
2005: Sylvain Ladoire; François Ghiringhelli; Patrick Manckoundia; R O Casasnovas; Eric Solary; Jean-François Besancenot; Pierre Pfitzenmeyer
[Treatment of cancer and hematological malignancy in elderly people (Part II)].
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne 2005;26(4):304-14.
2005: François Ghiringhelli; Sylvain Ladoire; Patrick Manckoundia; Bruno Chauffert; Eric Solary; Jean-François Besancenot; Pierre Pfitzenmeyer
[Treatment of cancer and hematological malignancy in elderly people: oncogeriatrics as a discipline for the future (Part I): geriatric evaluation and management of solid tumors].
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne 2005;26(3):216-25.
2004: Elise Schmitt; Arnaud Parcellier; François Ghiringhelli; Noelia Casares; Sandeep Gurbuxani; Nathalie M Droin; Ahmed Hamai; Marie O Pequignot; Arlette Hammann; Monique Moutet; Annie Fromentin; Guido Kroemer; Eric Solary; Carmen Garrido
Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C.
Cancer research 2004;64(8):2705-11.
2004: François Ghiringhelli; Nicolas Larmonier; Elise Schmitt; Arnaud Parcellier; Dominique Cathelin; Carmen Garrido; Bruno Chauffert; Eric Solary; Bernard Bonnotte; François Martin
CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative.
European journal of immunology 2004;34(2):336-44.
2003: Nicolas Larmonier; François Ghiringhelli; Claire B Larmonier; Monique Moutet; Annie Fromentin; Emmanuel Baulot; Eric Solary; Bernard Bonnotte; François Martin
Freshly isolated bone marrow cells induce death of various carcinoma cell lines.
International journal of cancer. Journal international du cancer 2003;107(5):747-56.