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Irene Ghobrial

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Ngo Hai T; Azab Abdel Kareem; Farag Mena; Jia Xiaoying; Melhem Molly M; Runnels Judith; Roccaro Aldo M; Azab Feda; Sacco Antonio; Leleu Xavier; Anderson Kenneth C; Ghobrial Irene M
Src tyrosine kinase regulates adhesion and chemotaxis in Waldenstrom macroglobulinemia.
Treon Steven P; Ioakimidis Leukothea; Soumerai Jacob D; Patterson Christopher J; Sheehy Patricia; Nelson Marybeth; Willen Michael; Matous Jeffrey; Mattern John; Diener Jakow G; Keogh George P; Myers Thomas J; Boral Andy; Birner Ann; Esseltine Dixie L; Ghobrial Irene M
Primary therapy of Waldenström macroglobulinemia with bortezomib, dexamethasone, and rituximab: WMCTG clinical trial 05-180.
Azab Abdel Kareem; Azab Feda; Blotta Simona; Pitsillides Costas M; Thompson Brian; Runnels Judith M; Roccaro Aldo M; Ngo Hai T; Melhem Molly R; Sacco Antonio; Jia Xiaoying; Anderson Kenneth C; Lin Charles P; Rollins Barrett J; Ghobrial Irene M
RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma.

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All Publications

2009: Ngo Hai T; Azab Abdel Kareem; Farag Mena; Jia Xiaoying; Melhem Molly M; Runnels Judith; Roccaro Aldo M; Azab Feda; Sacco Antonio; Leleu Xavier; Anderson Kenneth C; Ghobrial Irene M
Src tyrosine kinase regulates adhesion and chemotaxis in Waldenstrom macroglobulinemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6035-41.
2009: Treon Steven P; Ioakimidis Leukothea; Soumerai Jacob D; Patterson Christopher J; Sheehy Patricia; Nelson Marybeth; Willen Michael; Matous Jeffrey; Mattern John; Diener Jakow G; Keogh George P; Myers Thomas J; Boral Andy; Birner Ann; Esseltine Dixie L; Ghobrial Irene M
Primary therapy of Waldenström macroglobulinemia with bortezomib, dexamethasone, and rituximab: WMCTG clinical trial 05-180.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(23):3830-5.
2009: Azab Abdel Kareem; Azab Feda; Blotta Simona; Pitsillides Costas M; Thompson Brian; Runnels Judith M; Roccaro Aldo M; Ngo Hai T; Melhem Molly R; Sacco Antonio; Jia Xiaoying; Anderson Kenneth C; Lin Charles P; Rollins Barrett J; Ghobrial Irene M
RhoA and Rac1 GTPases play major and differential roles in stromal cell-derived factor-1-induced cell adhesion and chemotaxis in multiple myeloma.
Blood 2009;114(3):619-29.
2009: Roccaro Aldo M; Sacco Antonio; Thompson Brian; Leleu Xavier; Azab Abdel Kareem; Azab Feda; Runnels Judith; Jia Xiaoying; Ngo Hai T; Melhem Molly R; Lin Charles P; Ribatti Domenico; Rollins Barrett J; Witzig Thomas E; Anderson Kenneth C; Ghobrial Irene M
MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma.
Blood 2009;113(26):6669-80.
2009: Laubach Jacob P; Mitsiades Constantine S; Roccaro Aldo M; Ghobrial Irene M; Anderson Kenneth C; Richardson Paul G
Clinical challenges associated with bortezomib therapy in multiple myeloma and Waldenströms Macroglobulinemia.
Leukemia & lymphoma 2009;50(5):694-702.
2009: Braggio Esteban; Keats Jonathan J; Leleu Xavier; Van Wier Scott; Jimenez-Zepeda Victor H; Valdez Riccardo; Schop Roelandt F J; Price-Troska Tammy; Henderson Kimberly; Sacco Antonio; Azab Feda; Greipp Philip; Gertz Morie; Hayman Suzanne; Rajkumar S Vincent; Carpten John; Chesi Marta; Barrett Michael; Stewart A Keith; Dogan Ahmet; Bergsagel P Leif; Ghobrial Irene M; Fonseca Rafael
Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-kappaB signaling pathways in Waldenstrom's macroglobulinemia.
Cancer research 2009;69(8):3579-88.
2009: Pascal Laurent; Gay Julie; Willekens Christophe; Wemeau Mathieu; Balkaran Sandy; Robu Daniela; Roccaro Aldo; Morel Pierre; Ghobrial Irene; Leleu Xavier
Bortezomib and Waldenstrom's macroglobulinemia.
Expert opinion on pharmacotherapy 2009;10(5):909-16.
2009: Leleu Xavier; Hunter Zachary R; Xu Lian; Roccaro Aldo M; Moreau Anne-Sophie; Santos Daniel D; Hatjiharissi Evdoxia; Bakthavachalam Vinod; Adamia Sophia; Ho Allen W; Soumerai Jacob; Patterson Christopher J; Manning Robert J; Hamilton Susanna; Verselis Sigitas; Fox Edward; Carrasco Ruben; Ghobrial Irene M; Treon Steven P
Expression of regulatory genes for lymphoplasmacytic cell differentiation in Waldenstrom Macroglobulinemia.
British journal of haematology 2009;145(1):59-63.
2009: Azab Abdel Kareem; Runnels Judith M; Pitsillides Costas; Moreau Anne-Sophie; Azab Feda; Leleu Xavier; Jia Xiaoying; Wright Renee; Ospina Beatriz; Carlson Alicia L; Alt Clemens; Burwick Nicholas; Roccaro Aldo M; Ngo Hai T; Farag Mena; Melhem Molly R; Sacco Antonio; Munshi Nikhil C; Hideshima Teru; Rollins Barrett J; Anderson Kenneth C; Kung Andrew L; Lin Charles P; Ghobrial Irene M
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
Blood 2009;113(18):4341-51.
2009: Roccaro Aldo M; Sacco Antonio; Chen Changzhong; Runnels Judith; Leleu Xavier; Azab Feda; Azab Abdel Kareem; Jia Xiaoying; Ngo Hai T; Melhem Molly R; Burwick Nicholas; Varticovski Lyuba; Novina Carl D; Rollins Barrett J; Anderson Kenneth C; Ghobrial Irene M
microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia.
Blood 2009;113(18):4391-402.
2009: Roccaro Aldo M; Sacco Antonio; Leleu Xavier; Azab Abdel Kareem; Azab Feda; Runnels Judith; Jia Xiaoying; Ngo Hai T; Melhem Molly; Moreau Anne-Sophie; Ghobrial Irene M
Role of proteasome inhibition in Waldenström's macroglobulinemia.
Clinical lymphoma & myeloma 2009;9(1):94-6.
2009: Ghobrial Irene M; Leleu Xavier; Azab Abdel Kareem; Runnels Judith; Jia Xiaoying; Ngo Hai; Melhem Molly; Azab Feda; Sacco Antonio; Quang Phong; Burwick Nicholas; Moreau Anne-Sophie; Husu Emanuel; Farag Mena; Roccaro Aldo
Novel therapeutic agents in Waldenström's macroglobulinemia.
Clinical lymphoma & myeloma 2009;9(1):84-6.
2009: Leleu Xavier; Tamburini Jérome; Roccaro Aldo; Morel Pierre; Soumerai Jacob; Lévy Vincent; Wemeau Mathieu; Balkaran Sandy; Poulain Stephanie; Hunter Zachary R; Ghobrial Irene M; Treon Steven P; Leblond Veronique
Balancing risk versus benefit in the treatment of Waldenström's Macroglobulinemia patients with nucleoside analogue-based therapy.
Clinical lymphoma & myeloma 2009;9(1):71-3.
2009: Braggio Esteban; Keats Jonathan J; Leleu Xavier; Wier Scott Van; Jimenez-Zepeda Victor Hugo; Schop Roelandt F J; Chesi Marta; Barrett Michael; Stewart Alexander Keith; Dogan Ahmet; Bergsagel Peter Leif; Ghobrial Irene M; Fonseca Rafael
High-resolution genomic analysis in Waldenström's macroglobulinemia identifies disease-specific and common abnormalities with marginal zone lymphomas.
Clinical lymphoma & myeloma 2009;9(1):39-42.
2009: Gertz Morie A; Ghobrial Irene; Luc-Harousseau Jean
Multiple myeloma: biology, standard therapy, and transplant therapy.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(1 Suppl):46-52.
2009: Leleu Xavier; Soumerai Jacob; Roccaro Aldo; Hatjiharissi Evdoxia; Hunter Zachary R; Manning Robert; Ciccarelli Bryan T; Sacco Antonio; Ioakimidis Leukothea; Adamia Sophia; Moreau Anne-Sophie; Patterson Christopher J; Ghobrial Irene M; Treon Steven P
Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenström macroglobulinemia treated with nucleoside analogs.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(2):250-5.
2009: Leleu Xavier; Xu Lian; Jia Xiaoying; Sacco Antonio; Farag Mena; Hunter Zachary R; Moreau Anne-Sophie; Ngo Hai T; Hatjiharissi Evdoxia; Ho Allen W; Santos Daniel D; Adamia Sofia; O'Connor Kelly; Ciccarelli Bryan; Soumerai Jacob; Manning Robert J; Patterson Christopher J; Roccaro Aldo M; Ghobrial Irene M; Treon Steven P
Endoplasmic reticulum stress is a target for therapy in Waldenstrom macroglobulinemia.
Blood 2009;113(3):626-34.
2009: Venon Marie-Dominique; Roccaro Aldo M; Gay Julie; Moreau Anne-Sophie; Dulery Remy; Facon Thierry; Ghobrial Irene M; Leleu Xavier
Front line treatment of elderly multiple myeloma in the era of novel agents.
Biologics : targets & therapy 2009;3():99-109.
2008: Alsayed Yazan; Leleu Xavier; Leontovich Alexey; Oton Ana B; Melhem Mona; George Diane; Ghobrial Irene M
Proteomics analysis in post-transplant lymphoproliferative disorders.
European journal of haematology 2008;81(4):298-303.
2008: Leleu Xavier; Roccaro Aldo M; Moreau Anne-Sophie; Dupire Sophie; Robu Daniela; Gay Julie; Hatjiharissi Evdoxia; Burwik Nicholas; Ghobrial Irene M
Waldenstrom macroglobulinemia.
Cancer letters 2008;270(1):95-107.
2008: Roccaro Aldo M; Ghobrial Irene M; Blotta Simona; Treon Steven P; Malagola Michele; Anderson Kenneth C; Richardson Paul G; Russo Domenico
Advances in the treatment of monoclonal gammopaties: The emerging role of targeted therapy in plasma cell dyscrasias.
Biologics : targets & therapy 2008;2(3):419-31.
2008: Oton Ana B; Wang Hong; Leleu Xavier; Melhem Mona F; George Diane; Lacasce Ann; Foon Kenneth; Ghobrial Irene M
Clinical and pathological prognostic markers for survival in adult patients with post-transplant lymphoproliferative disorders in solid transplant.
Leukemia & lymphoma 2008;49(9):1738-44.
2008: Moreau Anne-Sophie; Jia Xiaoying; Patterson Christopher J; Roccaro Aldo M; Xu Lian; Sacco Antonio; O'Connor Kelly; Soumerai Jacob; Ngo Hai T; Hatjiharissi Evdoxia; Hunter Zachary R; Ciccarelli Bryan; Manning Robert; Ghobrial Irene M; Leleu Xavier; Treon Steven P
The HMG-CoA inhibitor, simvastatin, triggers in vitro anti-tumour effect and decreases IgM secretion in Waldenstrom macroglobulinaemia.
British journal of haematology 2008;142(5):775-85.
2008: Ansell Stephen M; Inwards David J; Rowland Kendrith M; Flynn Patrick J; Morton Roscoe F; Moore Dennis F; Kaufmann Scott H; Ghobrial Irene; Kurtin Paul J; Maurer Matthew; Allmer Christine; Witzig Thomas E
Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group.
Cancer 2008;113(3):508-14.
2008: Richardson Paul G; Mitsiades Constantine; Schlossman Robert; Ghobrial Irene; Hideshima Teru; Munshi Nikhil; Anderson Kenneth C
Bortezomib in the front-line treatment of multiple myeloma.
Expert review of anticancer therapy 2008;8(7):1053-72.
2008: Ngo Hai T; Leleu Xavier; Lee Jack; Jia Xiaoying; Melhem Molly; Runnels Judith; Moreau Anne-Sophie; Burwick Nicholas; Azab Abdel Kareem; Roccaro Aldo; Azab Feda; Sacco Antonio; Farag Mena; Sackstein Robert; Ghobrial Irene M
SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia.
Blood 2008;112(1):150-8.
2008: Burwick Nicholas; Roccaro Aldo M; Leleu Xavier; Ghobrial Irene M
Targeted therapies in Waldenström macroglobulinemia.
Current opinion in investigational drugs (London, England : 2000) 2008;9(6):631-7.
2008: Leleu Xavier; Moreau Anne-Sophie; Weller Edie; Roccaro Aldo M; Coiteux ValéRie; Manning Robert; Nelson Marybeth; Leduc Renee; Robu Daniela; Dupire Sophie; Hatjiharissi Evdoxia; Burwick Nicholas; Darre Stéphane; Hennache Bernadette; Treon Steven P; Facon Thierry; Gertz Morie A; Ghobrial Irene M
Serum immunoglobulin free light chain correlates with tumor burden markers in Waldenstrom macroglobulinemia.
Leukemia & lymphoma 2008;49(6):1104-7.
2008: Moreau Anne-Sophie; Sebti Yasmine; Duhamel Alain; Roccaro Aldo M; Coiteux Valérie; Gastinne Thomas; Le Friec Gaëlle; Burwick Nicholas; Amiot Laurence; Ho Allen W; Poulain Stephanie; Hennache Bernadette; Hunter Zachary R; Dessaint Jean-Paul; Ghobrial Irene M; Treon Steven P; Facon Thierry; Zorn Emmanuel; Leleu Xavier
Clinical relevance of soluble HLA class I molecules in Waldenstrom Macroglobulinemia.
European journal of haematology 2008;80(6):503-9.
2008: Leleu Xavier; Eeckhoute Jérôme; Jia Xiaoying; Roccaro Aldo M; Moreau Anne-Sophie; Farag Mena; Sacco Antonio; Ngo Hai T; Runnels Judith; Melhem Molly R; Burwick Nicolas; Azab Abdelkareem; Azab Feda; Hunter Zachary; Hatjiharissi Evdoxia; Carrasco Daniel R; Treon Steven P; Witzig Thomas E; Hideshima Teru; Brown Myles; Anderson Kenneth C; Ghobrial Irene M
Targeting NF-kappaB in Waldenstrom macroglobulinemia.
Blood 2008;111(10):5068-77.
2008: Roccaro Aldo M; Leleu Xavier; Sacco Antonio; Jia Xiaoying; Melhem Molly; Moreau Anne-Sophie; Ngo Hai T; Runnels Judith; Azab Abdelkareem; Azab Feda; Burwick Nicholas; Farag Mena; Treon Steven P; Palladino Michael A; Hideshima Teru; Chauhan Dharminder; Anderson Kenneth C; Ghobrial Irene M
Dual targeting of the proteasome regulates survival and homing in Waldenstrom macroglobulinemia.
Blood 2008;111(9):4752-63.
2008: Roccaro Aldo M; Leleu Xavier; Sacco Antonio; Moreau Anne-Sophie; Hatjiharissi Evdoxia; Jia Xiaoying; Xu Lian; Ciccarelli Bryan; Patterson Christopher J; Ngo Hai T; Russo Domenico; Vacca Angelo; Dammacco Franco; Anderson Kenneth C; Ghobrial Irene M; Treon Steven P
Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(6):1849-58.
2008: Huston Alissa; Leleu Xavier; Jia Xiaoying; Moreau Anne-Sophie; Ngo Hai T; Runnels Judith; Anderson Judy; Alsayed Yazan; Roccaro Aldo; Vallet Sonia; Hatjiharissi Evdoxia; Tai Yu-Tsu; Sportelli Peter; Munshi Nikhil; Richardson Paul; Hideshima Teru; Roodman David G; Anderson Kenneth C; Ghobrial Irene M
Targeting Akt and heat shock protein 90 produces synergistic multiple myeloma cell cytotoxicity in the bone marrow microenvironment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(3):865-74.
2007: Leleu Xavier; Jia Xiaoying; Runnels Judith; Ngo Hai T; Moreau Anne-Sophie; Farag Mena; Spencer Joel A; Pitsillides Costas M; Hatjiharissi Evdoxia; Roccaro Aldo; O'Sullivan Garrett; McMillin Douglas W; Moreno Daisy; Kiziltepe Tanyel; Carrasco Ruben; Treon Steven P; Hideshima Teru; Anderson Kenneth C; Lin Charles P; Ghobrial Irene M
The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.
Blood 2007;110(13):4417-26.
2007: Tai Yu-Tzu; Fulciniti Mariateresa; Hideshima Teru; Song Weihua; Leiba Merav; Li Xian-Feng; Rumizen Matthew; Burger Peter; Morrison Aileen; Podar Klaus; Chauhan Dharminder; Tassone Pierfrancesco; Richardson Paul; Munshi Nikhil C; Ghobrial Irene M; Anderson Kenneth C
Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis.
Blood 2007;110(5):1656-63.
2007: Treon Steven P; Hatjiharissi Evdoxia; Leleu Xavier; Moreau Anne-Sophie; Roccaro Aldo; Hunter Zachary R; Soumerai Jacob D; Ciccarelli Bryan; Xu Lian; Sacco Antonio; Ngo Hai T; Jia Xiaoying; Yang Cao; Adamia Sophia; Branagan Andrew R; Ho Allen W; Santos Daniel D; Tournilhac Olivier; Manning Robert J; Leduc Renee; O'Connor Kelly; Nelson Marybeth; Patterson Christopher J; Ghobrial Irene
Novel agents in the treatment of Waldenström's macroglobulinemia.
Clinical lymphoma & myeloma 2007;7 Suppl 5():S199-206.
2007: Younes Hashem; Leleu Xavier; Hatjiharissi Evdoxia; Moreau Anne-Sophie; Hideshima Teru; Richardson Paul; Anderson Kenneth C; Ghobrial Irene M
Targeting the phosphatidylinositol 3-kinase pathway in multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(13):3771-5.
2007: Ghobrial Joanne; Ghobrial Irene M; Mitsiades Constantine; Leleu Xavier; Hatjiharissi Evdoxia; Moreau Anne-Sophie; Roccaro Aldo; Schlossman Robert; Hideshima Teru; Anderson Kenneth C; Richardson Paul
Novel therapeutic avenues in myeloma: changing the treatment paradigm.
Oncology (Williston Park, N.Y.) 2007;21(7):785-92; discussion 798-800.
2007: Moreau Anne-Sophie; Jia Xiaoying; Ngo Hai T; Leleu Xavier; O'Sullivan Garrett; Alsayed Yazan; Leontovich Alexey; Podar Klaus; Kutok Jeffrey; Daley John; Lazo-Kallanian Suzan; Hatjiharissi Evdoxia; Raab Marc S; Xu Lian; Treon Steven P; Hideshima Teru; Anderson Kenneth C; Ghobrial Irene M
Protein kinase C inhibitor enzastaurin induces in vitro and in vivo antitumor activity in Waldenstrom macroglobulinemia.
Blood 2007;109(11):4964-72.
2007: Hatjiharissi Evdoxia; Ngo Hai; Leontovich Alexey A; Leleu Xavier; Timm Michael; Melhem Mona; George Diane; Lu Ganwei; Ghobrial Joanna; Alsayed Yazan; Zeismer Steven; Cabanela Miguel; Nehme Alex; Jia Xiaoying; Moreau Anne Sophie; Treon Steven P; Fonseca Rafael; Gertz Morie A; Anderson Kenneth C; Witzig Thomas E; Ghobrial Irene M
Proteomic analysis of waldenstrom macroglobulinemia.
Cancer research 2007;67(8):3777-84.
2007: Alsayed Yazan; Ngo Hai; Runnels Judith; Leleu Xavier; Singha Ujjal K; Pitsillides Costas M; Spencer Joel A; Kimlinger Teresa; Ghobrial Joanna M; Jia Xiaoying; Lu Ganwei; Timm Michael; Kumar Ashok; Côté Daniel; Veilleux Israel; Hedin Karen E; Roodman G David; Witzig Thomas E; Kung Andrew L; Hideshima Teru; Anderson Kenneth C; Lin Charles P; Ghobrial Irene M
Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.
Blood 2007;109(7):2708-17.
2007: Chauhan D; Velankar M; Brahmandam M; Hideshima T; Podar K; Richardson P; Schlossman R; Ghobrial I; Raje N; Munshi N; Anderson K C
A novel Bcl-2/Bcl-X(L)/Bcl-w inhibitor ABT-737 as therapy in multiple myeloma.
Oncogene 2007;26(16):2374-80.
2007: Ghobrial Irene M; Leleu Xavier; Hatjiharissi Evdoxia; Hideshima Teru; Mitsiades Constantine; Schlossman Robert; Anderson Kenneth C; Richardson Paul
Emerging drugs in multiple myeloma.
Expert opinion on emerging drugs 2007;12(1):155-63.
2007: Leleu Xavier; O'Connor Kelly; Ho Allen W; Santos Daniel D; Manning Robert; Xu Lian; Hatjiharissi Evdoxia; Moreau Anne-Sophie; Branagan Andrew R; Hunter Zachary R; Dimmock Elizabeth A; Soumerai Jacob; Patterson Christopher; Ghobrial Irene; Treon Steven P
Hepatitis C viral infection is not associated with Waldenström's macroglobulinemia.
American journal of hematology 2007;82(1):83-4.
2007: Richardson Paul; Mitsiades Constantine; Schlossman Robert; Ghobrial Irene; Hideshima Teru; Chauhan Dharminder; Munshi Nikhil; Anderson Kenneth
The treatment of relapsed and refractory multiple myeloma.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2007;():317-23.
2006: Francis Lanie K; Alsayed Yazan; Leleu Xavier; Jia Xiaoying; Singha Ujjal K; Anderson Judith; Timm Michael; Ngo Hai; Lu Ganwei; Huston Alissa; Ehrlich Lori A; Dimmock Elizabeth; Lentzsch Suzanne; Hideshima Teru; Roodman G David; Anderson Kenneth C; Ghobrial Irene M
Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(22):6826-35.
2006: Richardson Paul G; Mitsiades Constantine; Ghobrial Irene; Anderson Kenneth
Beyond single-agent bortezomib: combination regimens in relapsed multiple myeloma.
Current opinion in oncology 2006;18(6):598-608.
2006: Aggarwal Rohit; Ghobrial Irene M; Roodman G David
Chemokines in multiple myeloma.
Experimental hematology 2006;34(10):1289-95.
2006: Chng Wee J; Schop Roelandt F; Price-Troska Tammy; Ghobrial Irene; Kay Neil; Jelinek Diane F; Gertz Morie A; Dispenzieri Angela; Lacy Martha; Kyle Robert A; Greipp Philip R; Tschumper Renee C; Fonseca Rafael; Bergsagel Peter Leif
Gene-expression profiling of Waldenstrom macroglobulinemia reveals a phenotype more similar to chronic lymphocytic leukemia than multiple myeloma.
Blood 2006;108(8):2755-63.
2006: Schop Roelandt F J; Van Wier Scott A; Xu Ruifang; Ghobrial Irene; Ahmann Gregory J; Greipp Philip R; Kyle Robert A; Dispenzieri Angela; Lacy Martha Q; Rajkumar S Vincent; Gertz Morie A; Fonseca Rafael
6q deletion discriminates Waldenström macroglobulinemia from IgM monoclonal gammopathy of undetermined significance.
Cancer genetics and cytogenetics 2006;169(2):150-3.
2006: Ghobrial Irene M; Fonseca Rafael; Gertz Morie A; Plevak Matthew F; Larson Dirk R; Therneau Terry M; Wolf Robert C; Hoffmann Randi J; Lust John A; Witzig Thomas E; Lacy Martha Q; Dispenzieri Angela; Vincent Rajkumar S; Zeldenrust Stephen R; Greipp Philip R; Kyle Robert A
Prognostic model for disease-specific and overall mortality in newly diagnosed symptomatic patients with Waldenstrom macroglobulinaemia.
British journal of haematology 2006;133(2):158-64.
2006: Anderson Gülsüm; Gries Margarete; Kurihara Noriyoshi; Honjo Tadashi; Anderson Judy; Donnenberg Vera; Donnenberg Albert; Ghobrial Irene; Mapara Markus Y; Stirling David; Roodman David; Lentzsch Suzanne
Thalidomide derivative CC-4047 inhibits osteoclast formation by down-regulation of PU.1.
Blood 2006;107(8):3098-105.
2006: Hwang Janice Jin; Ghobrial Irene M; Anderson Kenneth C
New frontiers in the treatment of multiple myeloma.
TheScientificWorldJournal 2006;6():1475-503.
2005: Ghobrial Irene M; Habermann Thomas M; Maurer Matthew J; Geyer Susan M; Ristow Kay M; Larson Timothy S; Walker Randall C; Ansell Stephen M; Macon William R; Gores Gregory G; Stegall Mark D; McGregor Christopher G
Prognostic analysis for survival in adult solid organ transplant recipients with post-transplantation lymphoproliferative disorders.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(30):7574-82.
2005: Witzig Thomas E; Geyer Susan M; Ghobrial Irene; Inwards David J; Fonseca Rafael; Kurtin Paul; Ansell Stephen M; Luyun Ronnie; Flynn Patrick J; Morton Roscoe F; Dakhil Shaker R; Gross Howard; Kaufmann Scott H
Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(23):5347-56.
2005: Ehrlich Lori A; Chung Ho Yeon; Ghobrial Irene; Choi Sun Jin; Morandi Francesca; Colla Simona; Rizzoli Vittorio; Roodman G David; Giuliani Nicola
IL-3 is a potential inhibitor of osteoblast differentiation in multiple myeloma.
Blood 2005;106(4):1407-14.
2005: Ghobrial Irene M; Weenig Roger H; Pittlekow Mark R; Qu Guangzhi; Kurtin Paul J; Ristow Kay; Ansell Stephen M
Clinical outcome of patients with subcutaneous panniculitis-like T-cell lymphoma.
Leukemia & lymphoma 2005;46(5):703-8.
2005: Ghobrial Irene M; Witzig Thomas E; Adjei Alex A
Targeting apoptosis pathways in cancer therapy.
CA: a cancer journal for clinicians 2005;55(3):178-94.
2005: Ghobrial Irene M; McCormick Daniel J; Kaufmann Scott H; Leontovich Alexey A; Loegering David A; Dai Nga T; Krajnik Kelly L; Stenson Mary J; Melhem Mona F; Novak Anne J; Ansell Stephen M; Witzig Thomas E
Proteomic analysis of mantle-cell lymphoma by protein microarray.
Blood 2005;105(9):3722-30.
2005: Eckel-Passow Jeanette E; Hoering Antje; Therneau Terry M; Ghobrial Irene
Experimental design and analysis of antibody microarrays: applying methods from cDNA arrays.
Cancer research 2005;65(8):2985-9.
2005: Ghobrial Irene M; Habermann Thomas M; Ristow Kay M; Ansell Stephen M; Macon William; Geyer Suzan M; McGregor Christopher G
Prognostic factors in patients with post-transplant lymphoproliferative disorders (PTLD) in the rituximab era.
Leukemia & lymphoma 2005;46(2):191-6.
2005: Ghobrial Irene M; Habermann Thomas M; Macon William R; Ristow Kay M; Larson Timothy S; Walker Randall C; Ansell Stephen M; Gores Gregory J; Stegall Mark D; McGregor Christopher G
Differences between early and late posttransplant lymphoproliferative disorders in solid organ transplant patients: are they two different diseases?
Transplantation 2005;79(2):244-7.
2004: Ghobrial Irene M; Uslan Daniel Z; Call Timothy G; Witzig Thomas E; Gertz Morie A
Initial increase in the cryoglobulin level after rituximab therapy for type II cryoglobulinemia secondary to Waldenström macroglobulinemia does not indicate failure of response.
American journal of hematology 2004;77(4):329-30.
2004: Ghobrial Irene M; Fonseca Rafael; Greipp Philip R; Blood Emily; Rue Montserrat; Vesole David H; Gertz Morie A;
Initial immunoglobulin M 'flare' after rituximab therapy in patients diagnosed with Waldenstrom macroglobulinemia: an Eastern Cooperative Oncology Group Study.
Cancer 2004;101(11):2593-8.
2004: Ghobrial Irene M; Buadi Francis; Spinner Robert J; Colgan Joseph P; Wolanskyj Alexandra P; Dyck P James; Witzig Thomas E; Micallef Ivana N; O'Neill Brian Patrick
High-dose intravenous methotrexate followed by autologous stem cell transplantation as a potentially effective therapy for neurolymphomatosis.
Cancer 2004;100(11):2403-7.
2004: Ghobrial Irene M; Witzig Thomas E
Waldenström macroglobulinemia.
Current treatment options in oncology 2004;5(3):239-47.
2004: Ghobrial Irene; Witzig Thomas
Radioimmunotherapy: a new treatment modality for B-cell non-Hodgkin's lymphoma.
Oncology (Williston Park, N.Y.) 2004;18(5):623-30; discussion 633-4, 637-8, 640.
2004: Ghobrial Irene M; Bunch T Jared; Caplice Noel M; Edwards William D; Miller Dylan V; Litzow Mark R
Fatal coronary artery disease after unrelated donor bone marrow transplantation.
Mayo Clinic proceedings. Mayo Clinic 2004;79(3):403-6.
2004: Ghobrial Irene M; Bone Nancy D; Stenson Mary J; Novak Anne; Hedin Karen E; Kay Neil E; Ansell Stephen M
Expression of the chemokine receptors CXCR4 and CCR7 and disease progression in B-cell chronic lymphocytic leukemia/ small lymphocytic lymphoma.
Mayo Clinic proceedings. Mayo Clinic 2004;79(3):318-25.
2004: Ghobrial Irene M; Wolf Robert C; Pereira Denise L; Fonseca Rafael; White William L; Colgan Joseph P; Habermann Thomas M; Inwards David J; Markovic Svetomir N; Ansell Stephen M; Micallef Ivana N M; Porrata Luis F; Witzig Thomas E
Therapeutic options in patients with lymphoma and severe liver dysfunction.
Mayo Clinic proceedings. Mayo Clinic 2004;79(2):169-75.
2004: Riter Henry G; Ghobrial Irene M
Renal cell carcinoma with acrometastasis and scalp metastasis.
Mayo Clinic proceedings. Mayo Clinic 2004;79(1):76.
2003: Ghobrial Irene M; Otteman Larry A; White William L
An EBV-positive lymphoproliferative disorder after therapy with alemtuzumab.
The New England journal of medicine 2003;349(26):2570-2; discussion 2570-2.
2003: Ghobrial Irene M; Gertz Morie A; Fonseca Rafael
Waldenström macroglobulinaemia.
The lancet oncology 2003;4(11):679-85.
2003: Ghobrial Irene M; Rajkumar S Vincent
Management of thalidomide toxicity.
The journal of supportive oncology 2003;1(3):194-205.
2003: Ghobrial I M; Dispenzieri A; Bundy K L; Gastineau D A; Rajkumar S V; Therneau T M; Lacy M Q; Witzig T E; Litzow M R; Christensen B R; Hayman S; Pribula C G; Gertz M A
Effect of thalidomide on stem cell collection and engraftment in patients with multiple myeloma.
Bone marrow transplantation 2003;32(6):587-92.
2002: Ghobrial Irene M; Adjei Alex A
Inhibitors of the ras oncogene as therapeutic targets.
Hematology/oncology clinics of North America 2002;16(5):1065-88.

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