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Farideh Ghomashchi
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39
Gelb, Michael
13
Lambeau, Gérard
10
Jain, Mahendra
8
Yu, Bao-Zhu
7
Valentin, Eulogio
6
Lazdunski, Michel
5
Singer, Alan
4
Leslie, Christina
4
Sadilek, Martin
3
Koduri, Rao
3
Bollinger, James
3
Tucker, Dawn
3
Watson, Steve
3
Yokoyama, Kohei
3
Biochimie et Genie Enzymatique des Lipases, Laboratoire
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Geonetwork of Farideh Ghomashchi (preview)
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All Publications
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2009: Tucker Dawn E; Ghosh Moumita; Ghomashchi Farideh; Loper Robyn; Suram Saritha; John Bonnie St; Girotti Milena; Bollinger James G; Gelb Michael H; Leslie Christina C
Role of phosphorylation and basic residues in the catalytic domain of cytosolic phospholipase A2alpha in regulating interfacial kinetics and binding and cellular function.
The Journal of biological chemistry 2009;284(14):9596-611.
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2007: Ghosh Moumita; Loper Robyn; Ghomashchi Farideh; Tucker Dawn E; Bonventre Joseph V; Gelb Michael H; Leslie Christina C
Function, activity, and membrane targeting of cytosolic phospholipase A(2)zeta in mouse lung fibroblasts.
The Journal of biological chemistry 2007;282(16):11676-86.
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2007: Rouault Morgane; Le Calvez Catherine; Boilard Eric; Surrel Fanny; Singer Alan; Ghomashchi Farideh; Bezzine Sofiane; Scarzello Sabine; Bollinger James; Gelb Michael H; Lambeau Gérard
Recombinant production and properties of binding of the full set of mouse secreted phospholipases A2 to the mouse M-type receptor.
Biochemistry 2007;46(6):1647-62.
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2005: Tucker Dawn E; Stewart Allison; Nallan Laxman; Bendale Pravine; Ghomashchi Farideh; Gelb Michael H; Leslie Christina C
Group IVC cytosolic phospholipase A2gamma is farnesylated and palmitoylated in mammalian cells.
Journal of lipid research 2005;46(10):2122-33.
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2005: Rubin Barry B; Downey Gregory P; Koh Adeline; Degousee Norbert; Ghomashchi Farideh; Nallan Laxman; Stefanski Eva; Harkin Denis W; Sun Chunxiang; Smart Brian P; Lindsay Thomas F; Cherepanov Vera; Vachon Eric; Kelvin David; Sadilek Martin; Brown Glenn E; Yaffe Michael B; Plumb Jonathan; Grinstein Sergio; Glogauer Michael; Gelb Michael H
Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity.
The Journal of biological chemistry 2005;280(9):7519-29.
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2004: Bollinger James G; Diraviyam Karthikeyan; Ghomashchi Farideh; Murray Diana; Gelb Michael H
Interfacial binding of bee venom secreted phospholipase A2 to membranes occurs predominantly by a nonelectrostatic mechanism.
Biochemistry 2004;43(42):13293-304.
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2004: Mounier Carine M; Ghomashchi Farideh; Lindsay Margaret R; James Scott; Singer Alan G; Parton Robert G; Gelb Michael H
Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A(2) occurs predominantly during the secretory process and with the involvement of cytosolic phospholipase A(2)-alpha.
The Journal of biological chemistry 2004;279(24):25024-38.
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2004: Canaan Stéphane; Zádori Zoltán; Ghomashchi Farideh; Bollinger James; Sadilek Martin; Moreau Marie Eve; Tijssen Peter; Gelb Michael H
Interfacial enzymology of parvovirus phospholipases A2.
The Journal of biological chemistry 2004;279(15):14502-8.
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2003: Gurrieri Silvia; Fürstenberger Gerhard; Schadow Alexia; Haas Ulrike; Singer Alan G; Ghomashchi Farideh; Pfeilschifter Josef; Lambeau Gérard; Gelb Michael H; Kaszkin Marietta
Differentiation-dependent regulation of secreted phospholipases A2 in murine epidermis.
The Journal of investigative dermatology 2003;121(1):156-64.
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2002: Singer Alan G; Ghomashchi Farideh; Le Calvez Catherine; Bollinger James; Bezzine Sofiane; Rouault Morgane; Sadilek Martin; Nguyen Eric; Lazdunski Michel; Lambeau Gerard; Gelb Michael H
Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2.
The Journal of biological chemistry 2002;277(50):48535-49.
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2002: Pan Ying H; Yu Bao-Zhu; Singer Alan G; Ghomashchi Farideh; Lambeau Gerard; Gelb Michael H; Jain Mahendra K; Bahnson Brian J
Crystal structure of human group X secreted phospholipase A2. Electrostatically neutral interfacial surface targets zwitterionic membranes.
The Journal of biological chemistry 2002;277(32):29086-93.
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2002: Canaan Stéphane; Nielsen Robert; Ghomashchi Farideh; Robinson Bruce H; Gelb Michael H
Unusual mode of binding of human group IIA secreted phospholipase A2 to anionic interfaces as studied by continuous wave and time domain electron paramagnetic resonance spectroscopy.
The Journal of biological chemistry 2002;277(34):30984-90.
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2002: Degousee Norbert; Ghomashchi Farideh; Stefanski Eva; Singer Alan; Smart Brian P; Borregaard Niels; Reithmeier Reinhardt; Lindsay Thomas F; Lichtenberger Cornelia; Reinisch Walter; Lambeau Gerard; Arm Jonathan; Tischfield Jay; Gelb Michael H; Rubin Barry B
Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis.
The Journal of biological chemistry 2002;277(7):5061-73.
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2001: Ghomashchi F; Stewart A; Hefner Y; Ramanadham S; Turk J; Leslie C C; Gelb M H
A pyrrolidine-based specific inhibitor of cytosolic phospholipase A(2)alpha blocks arachidonic acid release in a variety of mammalian cells.
Biochimica et biophysica acta 2001;1513(2):160-6.
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2001: Murakami M; Koduri R S; Enomoto A; Shimbara S; Seki M; Yoshihara K; Singer A; Valentin E; Ghomashchi F; Lambeau G; Gelb M H; Kudo I
Distinct arachidonate-releasing functions of mammalian secreted phospholipase A2s in human embryonic kidney 293 and rat mastocytoma RBL-2H3 cells through heparan sulfate shuttling and external plasma membrane mechanisms.
The Journal of biological chemistry 2001;276(13):10083-96.
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2001: Cook T A; Ghomashchi F; Gelb M H; Florio S K; Beavo J A
The delta subunit of type 6 phosphodiesterase reduces light-induced cGMP hydrolysis in rod outer segments.
The Journal of biological chemistry 2001;276(7):5248-55.
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2000: Valentin E; Singer A G; Ghomashchi F; Lazdunski M; Gelb M H; Lambeau G
Cloning and recombinant expression of human group IIF-secreted phospholipase A(2).
Biochemical and biophysical research communications 2000;279(1):223-8.
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2000: Gelb M H; Valentin E; Ghomashchi F; Lazdunski M; Lambeau G
Cloning and recombinant expression of a structurally novel human secreted phospholipase A2.
The Journal of biological chemistry 2000;275(51):39823-6.
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2000: Hefner Y; Borsch-Haubold A G; Murakami M; Wilde J I; Pasquet S; Schieltz D; Ghomashchi F; Yates J R; Armstrong C G; Paterson A; Cohen P; Fukunaga R; Hunter T; Kudo I; Watson S P; Gelb M H
Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases.
The Journal of biological chemistry 2000;275(48):37542-51.
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2000: Cook T A; Ghomashchi F; Gelb M H; Florio S K; Beavo J A
Binding of the delta subunit to rod phosphodiesterase catalytic subunits requires methylated, prenylated C-termini of the catalytic subunits.
Biochemistry 2000;39(44):13516-23.
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2000: Mounier C M; Luchetta P; Lecut C; Koduri R S; Faure G; Lambeau G; Valentin E; Singer A; Ghomashchi F; Béguin S; Gelb M H; Bon C
Basic residues of human group IIA phospholipase A2 are important for binding to factor Xa and prothrombinase inhibition comparison with other mammalian secreted phospholipases A2.
European journal of biochemistry / FEBS 2000;267(16):4960-9.
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2000: Valentin E; Ghomashchi F; Gelb M H; Lazdunski M; Lambeau G
Novel human secreted phospholipase A(2) with homology to the group III bee venom enzyme.
The Journal of biological chemistry 2000;275(11):7492-6.
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2000: Bezzine S; Koduri R S; Valentin E; Murakami M; Kudo I; Ghomashchi F; Sadilek M; Lambeau G; Gelb M H
Exogenously added human group X secreted phospholipase A(2) but not the group IB, IIA, and V enzymes efficiently release arachidonic acid from adherent mammalian cells.
The Journal of biological chemistry 2000;275(5):3179-91.
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2000: Whitten M E; Yokoyama K; Schieltz D; Ghomashchi F; Lam D; Yates J R; Palczewski K; Gelb M H
Structural analysis of protein prenyl groups and associated C-terminal modifications.
Methods in enzymology 2000;316():436-51.
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1999: Buschbeck M; Ghomashchi F; Gelb M H; Watson S P; Börsch-Haubold A G
Stress stimuli increase calcium-induced arachidonic acid release through phosphorylation of cytosolic phospholipase A2.
The Biochemical journal 1999;344 Pt 2():359-66.
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1999: Valentin E; Ghomashchi F; Gelb M H; Lazdunski M; Lambeau G
On the diversity of secreted phospholipases A(2). Cloning, tissue distribution, and functional expression of two novel mouse group II enzymes.
The Journal of biological chemistry 1999;274(44):31195-202.
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1999: Börsch-Haubold A G; Ghomashchi F; Pasquet S; Goedert M; Cohen P; Gelb M H; Watson S P
Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways.
European journal of biochemistry / FEBS 1999;265(1):195-203.
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1999: Ghomashchi F; Loo R; Balsinde J; Bartoli F; Apitz-Castro R; Clark J D; Dennis E A; Gelb M H
Trifluoromethyl ketones and methyl fluorophosphonates as inhibitors of group IV and VI phospholipases A(2): structure-function studies with vesicle, micelle, and membrane assays.
Biochimica et biophysica acta 1999;1420(1-2):45-56.
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1998: Lin Y; Ghomashchi F; Nielsen R; Snitko Y; Yu B Z; Han S K; Cho W; Wilton D C; Jain M K; Robinson B H; Gelb M H
Binding of bee venom and human group IIa phospholipases A2 to membranes: a minor role for electrostatics.
Biochemical Society transactions 1998;26(3):341-5.
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1998: Ghomashchi F; Lin Y; Hixon M S; Yu B Z; Annand R; Jain M K; Gelb M H
Interfacial recognition by bee venom phospholipase A2: insights into nonelectrostatic molecular determinants by charge reversal mutagenesis.
Biochemistry 1998;37(19):6697-710.
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1997: Yu B Z; Ghomashchi F; Cajal Y; Annand R R; Berg O G; Gelb M H; Jain M K
Use of an imperfect neutral diluent and outer vesicle layer scooting mode hydrolysis to analyze the interfacial kinetics, inhibition, and substrate preferences of bee venom phospholipase A2.
Biochemistry 1997;36(13):3870-81.
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1997: Nicolas J P; Lin Y; Lambeau G; Ghomashchi F; Lazdunski M; Gelb M H
Localization of structural elements of bee venom phospholipase A2 involved in N-type receptor binding and neurotoxicity.
The Journal of biological chemistry 1997;272(11):7173-81.
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1995: Bayburt T; Yu B Z; Street I; Ghomashchi F; Laliberté F; Perrier H; Wang Z; Homan R; Jain M K; Gelb M H
Continuous, vesicle-based fluorimetric assays of 14- and 85-kDa phospholipases A2.
Analytical biochemistry 1995;232(1):7-23.
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1995: Ghomashchi F; Zhang X; Liu L; Gelb M H
Binding of prenylated and polybasic peptides to membranes: affinities and intervesicle exchange.
Biochemistry 1995;34(37):11910-8.
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1994: Bartoli F; Lin H K; Ghomashchi F; Gelb M H; Jain M K; Apitz-Castro R
Tight binding inhibitors of 85-kDa phospholipase A2 but not 14-kDa phospholipase A2 inhibit release of free arachidonate in thrombin-stimulated human platelets.
The Journal of biological chemistry 1994;269(22):15625-30.
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1993: Street I P; Lin H K; Laliberté F; Ghomashchi F; Wang Z; Perrier H; Tremblay N M; Huang Z; Weech P K; Gelb M H
Slow- and tight-binding inhibitors of the 85-kDa human phospholipase A2.
Biochemistry 1993;32(23):5935-40.
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1992: Jain M K; Ghomashchi F; Yu B Z; Bayburt T; Murphy D; Houck D; Brownell J; Reid J C; Solowiej J E; Wong S M
Fatty acid amides: scooting mode-based discovery of tight-binding competitive inhibitors of secreted phospholipases A2.
Journal of medicinal chemistry 1992;35(19):3584-6.
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1992: Yokoyama K; Goodwin G W; Ghomashchi F; Glomset J; Gelb M H
Protein prenyltransferases.
Biochemical Society transactions 1992;20(2):489-94.
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1992: Ghomashchi F; Schüttel S; Jain M K; Gelb M H
Kinetic analysis of a high molecular weight phospholipase A2 from rat kidney: divalent metal-dependent trapping of enzyme on product-containing vesicles.
Biochemistry 1992;31(15):3814-24.
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1991: Ghomashchi F; Yu B Z; Mihelich E D; Jain M K; Gelb M H
Kinetic characterization of phospholipase A2 modified by manoalogue.
Biochemistry 1991;30(40):9559-69.
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1991: Ghomashchi F; Yu B Z; Berg O; Jain M K; Gelb M H
Interfacial catalysis by phospholipase A2: substrate specificity in vesicles.
Biochemistry 1991;30(29):7318-29.
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1991: Ghomashchi F; O'Hare T; Clary D; Gelb M H
Interfacial catalysis by phospholipase A2: evaluation of the interfacial rate constants by steady-state isotope effect studies.
Biochemistry 1991;30(29):7298-305.
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1991: Yokoyama K; Goodwin G W; Ghomashchi F; Glomset J A; Gelb M H
A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(12):5302-6.
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