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Balaram Ghosh

Research Profile

Disorders

Asthma

Chemicals & Drugs

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India

Physiology

Procedures

Case Control Studies

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Living Beings

Genes & Molecular Sequences

Single Nucleotide Polymorphism

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Publications

TOP 3
Ulaganathan Mabalirajan; Rakhshinda Rehman; Suchita Singh; Vijay P Singh; Anurag Agrawal; Tanveer Ahmad; Jyotirmoi Aich; Shyam Biswal; Amit K Dinda; Kritika Khanna; Manish Kumar; SARVESH KUMAR; Geeta Leishangthem; Balaram Ghosh
Linoleic acid metabolite drives severe asthma by causing airway epithelial injury.
SARVESH KUMAR; Virinder S Parmar; Ashok K Prasad; Brajendra K Singh; Shyam Biswal; Balaram Ghosh
Ethyl 3',4',5'-trimethoxythionocinnamate modulates NF-κB and Nrf2 transcription factors.
Ulaganathan Mabalirajan; Rakhshinda Rehman; Suchita Singh; SARVESH KUMAR; Geeta Leishangthem; Anurag Agrawal; Tanveer Ahmad; Shyam Biswal; Amit Kumar Dinda; Balaram Ghosh
12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma.

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All Publications

2013: Ulaganathan Mabalirajan; Rakhshinda Rehman; Suchita Singh; Vijay P Singh; Anurag Agrawal; Tanveer Ahmad; Jyotirmoi Aich; Shyam Biswal; Amit K Dinda; Kritika Khanna; Manish Kumar; SARVESH KUMAR; Geeta Leishangthem; Balaram Ghosh
Linoleic acid metabolite drives severe asthma by causing airway epithelial injury.
Scientific reports 2013;3():1349.
2013: SARVESH KUMAR; Virinder S Parmar; Ashok K Prasad; Brajendra K Singh; Shyam Biswal; Balaram Ghosh
Ethyl 3',4',5'-trimethoxythionocinnamate modulates NF-κB and Nrf2 transcription factors.
European journal of pharmacology 2013;700(1-3):32-41.
2013: Ulaganathan Mabalirajan; Rakhshinda Rehman; Suchita Singh; SARVESH KUMAR; Geeta Leishangthem; Anurag Agrawal; Tanveer Ahmad; Shyam Biswal; Amit Kumar Dinda; Balaram Ghosh
12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma.
Scientific reports 2013;3():1540.
2013: SARVESH KUMAR; Ulanganathan Mabalirajan; Virinder S Parmar; Ashok K Prasad; Rakhshinda Rehman; Brajendra K Singh; Shyam Biswal; Balaram Ghosh
A novel cinnamate derivative attenuates asthma features and reduces bronchial epithelial injury in mouse model.
International immunopharmacology 2013;15(1):150-9.
2012: Jyotirmoi Aich; Anurag Agrawal; Tanveer Ahmad; Kritika Khanna; Ulanganathan Mabalirajan; Rakshinda Rehman; Balaram Ghosh
Resveratrol attenuates experimental allergic asthma in mice by restoring inositol polyphosphate 4 phosphatase (INPP4A).
International immunopharmacology 2012;14(4):438-43.
2011: Jyotsna Batra; Sunandini Chandra; Rajshekhar Chatterjee; Sudipta Das; Balaram Ghosh
Monocyte chemotactic protein (MCP3) promoter polymorphism is associated with atopic asthma in the Indian population.
The Journal of allergy and clinical immunology 2011;128(1):239-242.e3.
2011: Pankaj Gupta; Sumati Bhatia; Ashish Dhawan; Sakshi Balwani; Shatrughan Sharma; Raju Brahma; Rajpal Singh; Balaram Ghosh; Virinder S Parmar; Ashok K Prasad
Selective biocatalytic aminolysis of (±)-epichlorohydrin: synthesis and ICAM-1 inhibitory activity of (S)-(+)-3-arylamino-1-chloropropan-2-ols.
Bioorganic & medicinal chemistry 2011;19(7):2263-8.
2010: Ulanganathan Mabalirajan; Tanveer Ahmad; Geeta Leishangthem; Amit Dinda; Anurag Agrawal; Balaram Ghosh
L-arginine reduces mitochondrial dysfunction and airway injury in murine allergic airway inflammation.
International immunopharmacology 2010;10(12):1514-9.
2010: Pankaj Gupta; Sakshi Balwani; SARVESH KUMAR; Neha Aggarwal; Miriam Rossi; Sarah Paumier; Francesco Caruso; Paolo Bovicelli; Luciano Saso; Anthony L DePass; Ashok K Prasad; Virinder S Parmar; Balaram Ghosh
beta-sitosterol among other secondary metabolites of Piper galeatum shows inhibition of TNFalpha-induced cell adhesion molecule expression on human endothelial cells.
Biochimie 2010;92(9):1213-21.
2010: Tanveer Ahmad; Ulaganathan Mabalirajan; Balaram Ghosh; Anurag Agrawal
Altered asymmetric dimethyl arginine metabolism in allergically inflamed mouse lungs.
American journal of respiratory cell and molecular biology 2010;42(1):3-8.
2009: Anurag Agrawal; Anirban Sinha; Tanveer Ahmad; Jyotirmoi Aich; Priyanka Singh; Abhay Sharma; Balaram Ghosh
Maladaptation of critical cellular functions in asthma: bioinformatic analysis.
Physiological genomics 2009;40(1):1-7.
2009: Ulanganathan Mabalirajan; Jyotirmoi Aich; Anurag Agrawal; Balaram Ghosh
Mepacrine inhibits subepithelial fibrosis by reducing the expression of arginase and TGF-beta1 in an extended subacute mouse model of allergic asthma.
American journal of physiology. Lung cellular and molecular physiology 2009;297(3):L411-9.
2009: Jyotsna Batra; Balaram Ghosh
Genetic contribution of chemokine receptor 2 (CCR2) polymorphisms towards increased serum total IgE levels in Indian asthmatics.
Genomics 2009;94(3):161-8.
2009: Ulaganathan Mabalirajan; Amit Kumar Dinda; Surendra Kumar Sharma; Balaram Ghosh
Esculetin restores mitochondrial dysfunction and reduces allergic asthma features in experimental murine model.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(3):2059-67.
2009: Anita Goel; Ashok K Prasad; Virinder S Parmar; Balaram Ghosh; Neeru Saini
Apoptogenic effect of 7,8-diacetoxy-4-methylcoumarin and 7,8-diacetoxy-4-methylthiocoumarin in human lung adenocarcinoma cell line: role of NF-kappaB, Akt, ROS and MAP kinase pathway.
Chemico-biological interactions 2009;179(2-3):363-74.
2009: Amit Sharma; Manish Kumar; Jyotirmoi Aich; Manoj Hariharan; Samir K Brahmachari; Anurag Agrawal; Balaram Ghosh
Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(14):5761-6.
2009: Amrendra Kumar; Balaram Ghosh
Genetics of asthma: a molecular biologist perspective.
Clinical and molecular allergy : CMA 2009;7():7.
2009: Shilpy Sharma; Balaram Ghosh
Promoter polymorphism in the MS4A2 gene and asthma in the Indian population.
International archives of allergy and immunology 2009;149(3):208-18.
2009: Arjun Ram; Shashi Kant Singh; Vijay Pal Singh; SARVESH KUMAR; Balaram Ghosh
Inhaled carbenoxolone prevents allergic airway inflammation and airway hyperreactivity in a mouse model of asthma.
International archives of allergy and immunology 2009;149(1):38-46.
2009: Rajshekhar Chatterjee; Jyotsna Batra; Balaram Ghosh
A common exonic variant of interleukin21 confers susceptibility to atopic asthma.
International archives of allergy and immunology 2009;148(2):137-46.
2008: Ulaganathan Mabalirajan; Amit Kumar Dinda; SARVESH KUMAR; Reema Roshan; Pooja Gupta; Surendra Kumar Sharma; Balaram Ghosh
Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(5):3540-8.
2008: Jyotsna Batra; Balaram Ghosh
N-acetyltransferases as markers for asthma and allergic/atopic disorders.
Current drug metabolism 2008;9(6):546-53.
2008: Rajshekhar Chatterjee; Jyotsna Batra; Sudipta Das; Surendra Kumar Sharma; Balaram Ghosh
Genetic association of acidic mammalian chitinase with atopic asthma and serum total IgE levels.
The Journal of allergy and clinical immunology 2008;122(1):202-8, 208.e1-7.
2008: Arjun Ram; Ulanganathan Mabalirajan; Shashi Kant Singh; Vijay Pal Singh; Balaram Ghosh
Mepacrine alleviates airway hyperresponsiveness and airway inflammation in a mouse model of asthma.
International immunopharmacology 2008;8(6):893-9.
2008: Mamta Sharma; Jyotsna Batra; Ulanganathan Mabalirajan; Shilpy Sharma; Rana Nagarkatti; Jyotirmoi Aich; Surendra K Sharma; Pramod V Niphadkar; Balaram Ghosh
A genetic variation in inositol polyphosphate 4 phosphatase a enhances susceptibility to asthma.
American journal of respiratory and critical care medicine 2008;177(7):712-9.
2008: Naresh Singh; SARVESH KUMAR; Prabhjot Singh; Hanumantharao G Raj; Ashok K Prasad; Virinder S Parmar; Balaram Ghosh
Piper longum Linn. Extract inhibits TNF-alpha-induced expression of cell adhesion molecules by inhibiting NF-kappaB activation and microsomal lipid peroxidation.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2008;15(4):284-91.
2007: SARVESH KUMAR; Vandana Singhal; Reema Roshan; Amit Sharma; Gopal Waman Rembhotkar; Balaram Ghosh
Piperine inhibits TNF-alpha induced adhesion of neutrophils to endothelial monolayer through suppression of NF-kappaB and IkappaB kinase activation.
European journal of pharmacology 2007;575(1-3):177-86.
2007: Jyotsna Batra; Rajshekhar Chatterjee; Balaram Ghosh
Inducible nitric oxide synthase (iNOS): role in asthma pathogenesis.
Indian journal of biochemistry & biophysics 2007;44(5):303-9.
2007: Anita Goel; Ashok K Prasad; Virinder S Parmar; Balaram Ghosh; Neeru Saini
7,8-Dihydroxy-4-methylcoumarin induces apoptosis of human lung adenocarcinoma cells by ROS-independent mitochondrial pathway through partial inhibition of ERK/MAPK signaling.
FEBS letters 2007;581(13):2447-54.
2007: SARVESH KUMAR; Amit Sharma; Babita Madan; Vandana Singhal; Balaram Ghosh
Isoliquiritigenin inhibits IkappaB kinase activity and ROS generation to block TNF-alpha induced expression of cell adhesion molecules on human endothelial cells.
Biochemical pharmacology 2007;73(10):1602-12.
2007: SARVESH KUMAR; Brajendra K Singh; Anil K Pandey; Ajit Kumar; Sunil K Sharma; Hanumantharao G Raj; Ashok K Prasad; Erik Van Der Eycken; Virinder S Parmar; Balaram Ghosh
A chromone analog inhibits TNF-alpha induced expression of cell adhesion molecules on human endothelial cells via blocking NF-kappaB activation.
Bioorganic & medicinal chemistry 2007;15(8):2952-62.
2007: Mamta Sharma; Kamiya Mehla; Jyotsna Batra; Balaram Ghosh
Association of a chromosome 1q21 locus in close proximity to a late cornified envelope-like proline-rich 1 (LELP1) gene with total serum IgE levels.
Journal of human genetics 2007;52(4):378-83.
2007: Jyotsna Batra; Tej Pratap Singh; Ulanganathan Mabalirajan; Aditi Sinha; Rajendra Prasad; Balaram Ghosh
Association of inducible nitric oxide synthase with asthma severity, total serum immunoglobulin E and blood eosinophil levels.
Thorax 2007;62(1):16-22.
2006: Shilpy Sharma; Amit Sharma; SARVESH KUMAR; Surendra K Sharma; Balaram Ghosh
Association of TNF haplotypes with asthma, serum IgE levels, and correlation with serum TNF-alpha levels.
American journal of respiratory cell and molecular biology 2006;35(4):488-95.
2006: Arjun Ram; Ulanganathan Mabalirajan; Moumita Das; Indranil Bhattacharya; Amit Dinda; Sharad V Gangal; Balaram Ghosh
Glycyrrhizin alleviates experimental allergic asthma in mice.
International immunopharmacology 2006;6(9):1468-77.
2006: Jyotsna Batra; Surendra K Sharma; Balaram Ghosh
Arylamine N-acetyltransferase gene polymorphisms: markers for atopic asthma, serum IgE and blood eosinophil counts.
Pharmacogenomics 2006;7(5):673-82.
2005: SARVESH KUMAR; Pragya Arya; Chandrani Mukherjee; Brajendra K Singh; Naresh Singh; Virinder S Parmar; Ashok K Prasad; Balaram Ghosh
Novel aromatic ester from Piper longum and its analogues inhibit expression of cell adhesion molecules on endothelial cells.
Biochemistry 2005;44(48):15944-52.
2005: R Chatterjee; Jyotsna Batra; A Kumar; Ulanganathan Mabalirajan; S Nahid; Pramod V Niphadkar; Balaram Ghosh
Interleukin-10 promoter polymorphisms and atopic asthma in North Indians.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2005;35(7):914-9.
2005: Ritushree Kukreti; Pallav Bhatnagar; Chandrika B-Rao; Simone Gupta; Babita Madan; Chinmoyee Das; Randeep Guleria; Amita Umesh Athavale; Samir K Brahmachari; Balaram Ghosh
Beta(2)-adrenergic receptor polymorphisms and response to salbutamol among Indian asthmatics*.
Pharmacogenomics 2005;6(4):399-410.
2005: Ulaganathan Mabalirajan; Tamilarasu Kadhiravan; Surendra K Sharma; Banga Amit; Balaram Ghosh
Th(2) immune response in patients with dengue during defervescence: preliminary evidence.
The American journal of tropical medicine and hygiene 2005;72(6):783-5.
2005: Kamalpreet Nagpal; Shilpy Sharma; Chandrika B-Rao; Sanober Nahid; Pramod V Niphadkar; Surendra K Sharma; Balaram Ghosh
TGFbeta1 haplotypes and asthma in Indian populations.
The Journal of allergy and clinical immunology 2005;115(3):527-33.
2005: SARVESH KUMAR; Brajendra K Singh; Neerja Kalra; Vineet Kumar; Ajit Kumar; Ashok K Prasad; Hanumantharao G Raj; Virinder S Parmar; Balaram Ghosh
Novel thiocoumarins as inhibitors of TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) and microsomal lipid peroxidation.
Bioorganic & medicinal chemistry 2005;13(5):1605-13.
2005: Shilpy Sharma; Deepti Mann; Tej Pratap Singh; Balaram Ghosh
Lack of association of histamine-N-methyltransferase (HNMT) polymorphisms with asthma in the Indian population.
Journal of human genetics 2005;50(12):611-7.
2005: Jyotsna Batra; M Sharma; R Chatterjee; Shilpy Sharma; Ulanganathan Mabalirajan; Balaram Ghosh
CCR5 Delta32 deletion and atopic asthma in India.
Thorax 2005;60(1):85.
2005: Jyotsna Batra; Pramod V Niphadkar; Surendra K Sharma; Balaram Ghosh
Uteroglobin-related protein 1(UGRP1) gene polymorphisms and atopic asthma in the Indian population.
International archives of allergy and immunology 2005;136(1):1-6.
2004: Arjun Ram; Moumita Das; Sharad V Gangal; Balaram Ghosh
Para-Bromophenacyl bromide alleviates airway hyperresponsiveness and modulates cytokines, IgE and eosinophil levels in ovalbumin-sensitized and -challenged mice.
International immunopharmacology 2004;4(13):1697-707.
2004: S Sharma; Rana Nagarkatti; Chandrika B-Rao; Pramod V Niphadkar; Vannankandi Vijayan; Shilpy Sharma; Balaram Ghosh
A_16_C haplotype in the FcepsilonRIbeta gene confers a higher risk for atopic asthma in the Indian population.
Clinical genetics 2004;66(5):417-25.
2004: Mamta Sharma; Jyotsna Batra; Ulanganathan Mabalirajan; Sangeeta Goswami; Dipyaman Ganguly; Brajen Lahkar; N K Bhatia; Amrendra Kumar; Balaram Ghosh
Suggestive evidence of association of C-159T functional polymorphism of the CD14 gene with atopic asthma in northern and northwestern Indian populations.
Immunogenetics 2004;56(7):544-7.
2004: Rana Nagarkatti; Chandrika B-Rao; Vannankandi Vijayan; Surendra K Sharma; Balaram Ghosh
Signal transducer and activator of transcription 6 haplotypes and asthma in the Indian population.
American journal of respiratory cell and molecular biology 2004;31(3):317-21.
2004: Rana Nagarkatti; Raj Kumar; Surendra K Sharma; Balaram Ghosh
Association of IL4 gene polymorphisms with asthma in North Indians.
International archives of allergy and immunology 2004;134(3):206-12.
2004: Babita Madan; Ashok K Prasad; Virinder S Parmar; Balaram Ghosh
1,4-dihydroxyxanthone modulates the adhesive property of endothelial cells by inhibiting intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and E-selectin.
Bioorganic & medicinal chemistry 2004;12(6):1431-7.
2004: Shilpy Sharma; Balaram Ghosh
Association of an intragenic microsatellite marker in the CC16 gene with asthma in the Indian population.
Journal of human genetics 2004;49(12):677-83.
2003: Babita Madan; B C Mandal; SARVESH KUMAR; Balaram Ghosh
Canscora decussata (Roxb.) Schult (Gentianaceae) inhibits LPS-induced expression of ICAM-1 and E-selectin on endothelial cells and carageenan-induced paw-edema in rats.
Journal of ethnopharmacology 2003;89(2-3):211-6.
2003: Arjun Ram; Moumita Das; Balaram Ghosh
Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs.
Biological & pharmaceutical bulletin 2003;26(7):1021-4.
2003: Balaram Ghosh; Shilpy Sharma; Rana Nagarkatti
Genetics of asthma: current research paving the way for development of personalized drugs.
The Indian journal of medical research 2003;117():185-97.
2003: Babita Madan; Balaram Ghosh
Diferuloylmethane inhibits neutrophil infiltration and improves survival of mice in high-dose endotoxin shock.
Shock (Augusta, Ga.) 2003;19(1):91-6.
2002: Babita Madan; Ishwar Singh; Ajit Kumar; Ashok K Prasad; Hanumantharao G Raj; Virinder S Parmar; Balaram Ghosh
Xanthones as inhibitors of microsomal lipid peroxidation and TNF-alpha induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs).
Bioorganic & medicinal chemistry 2002;10(11):3431-6.
2002: Rana Nagarkatti; Chandrika B-Rao; Jai Prakash Rishi; Rajesh Chetiwal; Vipul Shandilya; Vannankandi Vijayan; Raj Kumar; Harish K Pemde; Surendra K Sharma; Sweety Sharma; Anand B Singh; Sharad V Gangal; Balaram Ghosh
Association of IFNG gene polymorphism with asthma in the Indian population.
The Journal of allergy and clinical immunology 2002;110(3):410-2.
2002: Babita Madan; Balaram Ghosh
Canscora decussata promotes adhesion of neutrophils to human umbilical vein endothelial cells.
Journal of ethnopharmacology 2002;79(2):229-35.
2001: Babita Madan; W N Gade; Balaram Ghosh
Curcuma longa activates NF-kappaB and promotes adhesion of neutrophils to human umbilical vein endothelial cells.
Journal of ethnopharmacology 2001;75(1):25-32.
2000: Babita Madan; S Batra; Balaram Ghosh
2'-hydroxychalcone inhibits nuclear factor-kappaB and blocks tumor necrosis factor-alpha- and lipopolysaccharide-induced adhesion of neutrophils to human umbilical vein endothelial cells.
Molecular pharmacology 2000;58(3):526-34.
1999: B Gupta; Balaram Ghosh
Curcuma longa inhibits TNF-alpha induced expression of adhesion molecules on human umbilical vein endothelial cells.
International journal of immunopharmacology 1999;21(11):745-57.
1999: R Manjeet K; Balaram Ghosh
Quercetin inhibits LPS-induced nitric oxide and tumor necrosis factor-alpha production in murine macrophages.
International journal of immunopharmacology 1999;21(7):435-43.