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Sankar Ghosh

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
11
Coca-Prados, Miguel
11
Hayden, Matthew
11
May, Michael
8
Jimi, Eijiro
7
Voll, Reinhard
5
Kopp, Elizabeth
5
D'Acquisto, Fulvio
5
Flavell, Richard
5
Zhong, Haihong
4
Martin-Vasallo, Pablo
4
Xiao, Changchun
4
Marienfeld, Ralf
4
Phillips, Roderick
3
Lee, Ki-Young
3
Tempst, Paul

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Publications

TOP 3
Park Sung-Gyoo; Schulze-Luehrman Jan; Hayden Matthew S; Hashimoto Naoko; Ogawa Wataru; Kasuga Masato; Ghosh Sankar
The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells.
Sullivan C A W; Ghosh S; Ocal I T; Camp R L; Rimm David L; Chung G G
Microvessel area using automated image analysis is reproducible and is associated with prognosis in breast cancer.
Ghosh Sankar; Hayden Matthew S
New regulators of NF-kappaB in inflammation.

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All Publications

2009: Park Sung-Gyoo; Schulze-Luehrman Jan; Hayden Matthew S; Hashimoto Naoko; Ogawa Wataru; Kasuga Masato; Ghosh Sankar
The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells.
Nature immunology 2009;10(2):158-66.
2009: Sullivan C A W; Ghosh S; Ocal I T; Camp R L; Rimm David L; Chung G G
Microvessel area using automated image analysis is reproducible and is associated with prognosis in breast cancer.
Human pathology 2009;40(2):156-65.
2008: Ghosh Sankar; Hayden Matthew S
New regulators of NF-kappaB in inflammation.
Nature reviews. Immunology 2008;8(11):837-48.
2008: Jimi Eijiro; Strickland Ian; Voll Reinhard E; Long Meixiao; Ghosh Sankar
Differential role of the transcription factor NF-kappaB in selection and survival of CD4+ and CD8+ thymocytes.
Immunity 2008;29(4):523-37.
2008: Dong Jie; Jimi Eijiro; Zhong Haihong; Hayden Matthew S; Ghosh Sankar
Repression of gene expression by unphosphorylated NF-kappaB p65 through epigenetic mechanisms.
Genes & development 2008;22(9):1159-73.
2008: Hayden Matthew S; Ghosh Sankar
Shared principles in NF-kappaB signaling.
Cell 2008;132(3):344-62.
2008: Palkowitsch Lysann; Leidner Julia; Ghosh Sankar; Marienfeld Ralf B
Phosphorylation of serine 68 in the IkappaB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor necrosis factor-alpha-induced NF-kappaB activity.
The Journal of biological chemistry 2008;283(1):76-86.
2007: Chapoval Svetlana P; Al-Garawi Amal; Lora Jose M; Strickland Ian; Ma Bing; Lee Patty J; Homer Robert J; Ghosh Sankar; Coyle Anthony J; Elias Jack A
Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):7030-41.
2006: Hayden Matthew S; West A Phillip; Ghosh Sankar
SnapShot: NF-kappaB signaling pathways.
Cell 2006;127(6):1286-7.
2006: Marienfeld Ralf B; Palkowitsch Lysann; Ghosh Sankar
Dimerization of the I kappa B kinase-binding domain of NEMO is required for tumor necrosis factor alpha-induced NF-kappa B activity.
Molecular and cellular biology 2006;26(24):9209-19.
2006: Schulze-Luehrmann Jan; Ghosh Sankar
Antigen-receptor signaling to nuclear factor kappa B.
Immunity 2006;25(5):701-15.
2006: Hayden M S; West A P; Ghosh S
NF-kappaB and the immune response.
Oncogene 2006;25(51):6758-80.
2006: Igarashi Hideya; Baba Yoshihiro; Nagai Yoshinori; Jimi Eijiro; Ghosh Sankar; Kincade Paul W
NF-kappaB is dispensable for normal lymphocyte development in bone marrow but required for protection of progenitors from TNFalpha.
International immunology 2006;18(5):653-9.
2006: Shim Jae-Hyuck; Xiao Changchun; Hayden Matthew S; Lee Ki-Young; Trombetta E Sergio; Pypaert Marc; Nara Atsuki; Yoshimori Tamotsu; Wilm Bettina; Erdjument-Bromage Hediye; Tempst Paul; Hogan Brigid L M; Mellman Ira; Ghosh Sankar
CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis.
The Journal of cell biology 2006;172(7):1045-56.
2006: West A Phillip; Koblansky Anna Alicia; Ghosh Sankar
Recognition and signaling by toll-like receptors.
Annual review of cell and developmental biology 2006;22():409-37.
2005: Shim Jae-Hyuck; Xiao Changchun; Paschal Amber E; Bailey Shannon T; Rao Ping; Hayden Matthew S; Lee Ki-Young; Bussey Crystal; Steckel Michael; Tanaka Nobuyuki; Yamada Gen; Akira Shizuo; Matsumoto Kunihiro; Ghosh Sankar
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo.
Genes & development 2005;19(22):2668-81.
2005: Jimi Eijiro; Phillips Roderick J; Rincon Mercedes; Voll Reinhard; Karasuyama Hajime; Flavell Richard; Ghosh Sankar
Activation of NF-kappaB promotes the transition of large, CD43+ pre-B cells to small, CD43- pre-B cells.
International immunology 2005;17(6):815-25.
2005: Ziegler Elizabeth C; Ghosh Sankar
Regulating inducible transcription through controlled localization.
Science's STKE : signal transduction knowledge environment 2005;2005(284):re6.
2005: Lee Ki-Young; D'Acquisto Fulvio; Hayden Matthew S; Shim Jae-Hyuck; Ghosh Sankar
PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation.
Science (New York, N.Y.) 2005;308(5718):114-8.
2005: di Meglio Paola; Ianaro Angela; Ghosh Sankar
Amelioration of acute inflammation by systemic administration of a cell-permeable peptide inhibitor of NF-kappaB activation.
Arthritis and rheumatism 2005;52(3):951-8.
2005: Xiao Changchun; Ghosh Sankar
NF-kappaB, an evolutionarily conserved mediator of immune and inflammatory responses.
Advances in experimental medicine and biology 2005;560():41-5.
2004: May Michael J; Larsen Signe E; Shim Jae Hyuck; Madge Lisa A; Ghosh Sankar
A novel ubiquitin-like domain in IkappaB kinase beta is required for functional activity of the kinase.
The Journal of biological chemistry 2004;279(44):45528-39.
2004: Hayden Matthew S; Ghosh Sankar
Signaling to NF-kappaB.
Genes & development 2004;18(18):2195-224.
2004: Jimi Eijiro; Aoki Kazuhiro; Saito Hiroaki; D'Acquisto Fulvio; May Michael J; Nakamura Ichiro; Sudo Testuo; Kojima Takefumi; Okamoto Fujio; Fukushima Hidefumi; Okabe Koji; Ohya Keiichi; Ghosh Sankar
Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo.
Nature medicine 2004;10(6):617-24.
2004: Zhang Dekai; Zhang Guolong; Hayden Matthew S; Greenblatt Matthew B; Bussey Crystal; Flavell Richard A; Ghosh Sankar
A toll-like receptor that prevents infection by uropathogenic bacteria.
Science (New York, N.Y.) 2004;303(5663):1522-6.
2003: Xiao Changchun; Shim Jae-hyuck; Klüppel Michael; Zhang Samuel Shao-Min; Dong Chen; Flavell Richard A; Fu Xin-Yuan; Wrana Jeffrey L; Hogan Brigid L M; Ghosh Sankar
Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.
Genes & development 2003;17(23):2933-49.
2003: Wu Chun; Ghosh Sankar
Differential phosphorylation of the signal-responsive domain of I kappa B alpha and I kappa B beta by I kappa B kinases.
The Journal of biological chemistry 2003;278(34):31980-7.
2003: Ma Xian-Yong; Wang Hong; Ding Bo; Zhong Haihong; Ghosh Sankar; Lengyel Peter
The interferon-inducible p202a protein modulates NF-kappaB activity by inhibiting the binding to DNA of p50/p65 heterodimers and p65 homodimers while enhancing the binding of p50 homodimers.
The Journal of biological chemistry 2003;278(25):23008-19.
2003: Marienfeld Ralf; May Michael J; Berberich Ingolf; Serfling Edgar; Ghosh Sankar; Neumann Manfred
RelB forms transcriptionally inactive complexes with RelA/p65.
The Journal of biological chemistry 2003;278(22):19852-60.
2002: Budde Lucy M; Wu Chun; Tilman Christopher; Douglas Iris; Ghosh Sankar
Regulation of IkappaBbeta expression in testis.
Molecular biology of the cell 2002;13(12):4179-94.
2002: May Michael J; Marienfeld Ralf B; Ghosh Sankar
Characterization of the Ikappa B-kinase NEMO binding domain.
The Journal of biological chemistry 2002;277(48):45992-6000.
2002: Ghosh Sankar; Karin Michael
Missing pieces in the NF-kappaB puzzle.
Cell 2002;109 Suppl():S81-96.
2002: Zhong Haihong; May Michael J; Jimi Eijiro; Ghosh Sankar
The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1.
Molecular cell 2002;9(3):625-36.
2002: Zhang Guolong; Ghosh Sankar
Negative regulation of toll-like receptor-mediated signaling by Tollip.
The Journal of biological chemistry 2002;277(9):7059-65.
2002: D'Acquisto Fulvio; May Michael J; Ghosh Sankar
Inhibition of nuclear factor kappa B (NF-B): an emerging theme in anti-inflammatory therapies.
Molecular interventions 2002;2(1):22-35.
2002: Kim Dongsoo; Xu Min; Nie Lei; Peng Xiao-Cong; Jimi Eijiro; Voll Reinhard E; Nguyen Thuan; Ghosh Sankar; Sun Xiao-Hong
Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities.
Immunity 2002;16(1):9-21.
2001: D'Acquisto F; Ghosh S
PACT and PKR: turning on NF-kappa B in the absence of virus.
Science's STKE : signal transduction knowledge environment 2001;2001(89):re1.
2001: Zhang G; Ghosh S
Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity.
The Journal of clinical investigation 2001;107(1):13-9.
2000: Voll R E; Jimi E; Phillips R J; Barber D F; Rincon M; Hayday A C; Flavell R A; Ghosh S
NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development.
Immunity 2000;13(5):677-89.
2000: May M J; D'Acquisto F; Madge L A; Glöckner J; Pober J S; Ghosh S
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex.
Science (New York, N.Y.) 2000;289(5484):1550-4.
2000: Li B; Yu H; Zheng W; Voll R; Na S; Roberts A W; Williams D A; Davis R J; Ghosh S; Flavell R A
Role of the guanosine triphosphatase Rac2 in T helper 1 cell differentiation.
Science (New York, N.Y.) 2000;288(5474):2219-22.
2000: Millet I; Phillips R J; Sherwin R S; Ghosh S; Voll R E; Flavell R A; Vignery A; Rincón M
Inhibition of NF-kappaB activity and enhancement of apoptosis by the neuropeptide calcitonin gene-related peptide.
The Journal of biological chemistry 2000;275(20):15114-21.
2000: Budde L M; Ghosh S
Cloning and characterization of the gene encoding mouse IkappaBbeta.
Gene 2000;247(1-2):279-86.
2000: Fenwick C; Na S Y; Voll R E; Zhong H; Im S Y; Lee J W; Ghosh S
A subclass of Ras proteins that regulate the degradation of IkappaB.
Science (New York, N.Y.) 2000;287(5454):869-73.
2000: Zhang G; Ghosh S
Molecular mechanisms of NF-kappaB activation induced by bacterial lipopolysaccharide through Toll-like receptors.
Journal of endotoxin research 2000;6(6):453-7.
1999: Wu C; Ghosh S
beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta.
The Journal of biological chemistry 1999;274(42):29591-4.
1999: Kopp E; Medzhitov R; Carothers J; Xiao C; Douglas I; Janeway C A; Ghosh S
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway.
Genes & development 1999;13(16):2059-71.
1999: May M J; Ghosh S
IkappaB kinases: kinsmen with different crafts.
Science (New York, N.Y.) 1999;284(5412):271-3.
1999: Ghosh S
Regulation of inducible gene expression by the transcription factor NF-kappaB.
Immunologic research 1999;19(2-3):183-9.
1998: Medzhitov R; Preston-Hurlburt P; Kopp E; Stadlen A; Chen C; Ghosh S; Janeway C A
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.
Molecular cell 1998;2(2):253-8.
1998: Zhong H; Voll R E; Ghosh S
Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300.
Molecular cell 1998;1(5):661-71.
1998: May M J; Ghosh S
Signal transduction through NF-kappa B.
Immunology today 1998;19(2):80-8.
1998: Ghosh S; May M J; Kopp E B
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses.
Annual review of immunology 1998;16():225-60.
1997: Ray P; Yang L; Zhang D H; Ghosh S K; Ray A
Selective up-regulation of cytokine-induced RANTES gene expression in lung epithelial cells by overexpression of IkappaBR.
The Journal of biological chemistry 1997;272(32):20191-7.
1997: Phillips R J; Ghosh S
Regulation of IkappaB beta in WEHI 231 mature B cells.
Molecular and cellular biology 1997;17(8):4390-6.
1997: Zhong H; SuYang H; Erdjument-Bromage H; Tempst P; Ghosh S
The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism.
Cell 1997;89(3):413-24.
1997: May M J; Ghosh S
Rel/NF-kappa B and I kappa B proteins: an overview.
Seminars in cancer biology 1997;8(2):63-73.
1996: Phillips R J; Gustafson S; Ghosh S
Identification of a novel NF-kappaB p50-related protein in B lymphocytes.
Molecular and cellular biology 1996;16(12):7089-97.
1996: Suyang H; Phillips R; Douglas I; Ghosh S
Role of unphosphorylated, newly synthesized I kappa B beta in persistent activation of NF-kappa B.
Molecular and cellular biology 1996;16(10):5444-9.
1996: Johnson D R; Douglas I; Jahnke A; Ghosh S; Pober J S
A sustained reduction in IkappaB-beta may contribute to persistent NF-kappaB activation in human endothelial cells.
The Journal of biological chemistry 1996;271(27):16317-22.
1996: Lin L; Ghosh S
A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit.
Molecular and cellular biology 1996;16(5):2248-54.
1996: Min W; Ghosh S; Lengyel P
The interferon-inducible p202 protein as a modulator of transcription: inhibition of NF-kappa B, c-Fos, and c-Jun activities.
Molecular and cellular biology 1996;16(1):359-68.
1995: Coca-Prados M; Fernández-Cabezudo M J; Sánchez-Torres J; Crabb J W; Ghosh S
Cell-specific expression of the human Na+,K(+)-ATPase beta 2 subunit isoform in the nonpigmented ciliary epithelium.
Investigative ophthalmology & visual science 1995;36(13):2717-28.
1995: Thompson J E; Phillips R J; Erdjument-Bromage H; Tempst P; Ghosh S
I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B.
Cell 1995;80(4):573-82.
1995: Ghosh G; van Duyne G; Ghosh S; Sigler P B
Structure of NF-kappa B p50 homodimer bound to a kappa B site.
Nature 1995;373(6512):303-10.
1995: Kopp E B; Ghosh S
NF-kappa B and rel proteins in innate immunity.
Advances in immunology 1995;58():1-27.
1994: Escribano J; Hernando N; Ghosh S; Crabb J; Coca-Prados M
cDNA from human ocular ciliary epithelium homologous to beta ig-h3 is preferentially expressed as an extracellular protein in the corneal epithelium.
Journal of cellular physiology 1994;160(3):511-21.
1994: Kopp E; Ghosh S
Inhibition of NF-kappa B by sodium salicylate and aspirin.
Science (New York, N.Y.) 1994;265(5174):956-9.
1994: Hernando N; Martin-Vasallo P; Ghosh S; Ghosh P K; Swaroop A; Coca-Prados M
Nucleotide sequence of a cDNA for the beta 2 subunit isoform of Na+,K(+)-ATPase from human retina.
Biochimica et biophysica acta 1994;1189(1):109-11.
1993: Martín-Alonso J M; Ghosh S; Coca-Prados M
Cloning of the bovine plasma selenium-dependent glutathione peroxidase (GP) cDNA from the ocular ciliary epithelium: expression of the plasma and cellular forms within the mammalian eye.
Journal of biochemistry 1993;114(2):284-91.
1993: Martin-Alonso J M; Ghosh S; Hernando N; Crabb J W; Coca-Prados M
Differential expression of the cellular retinaldehyde-binding protein in bovine ciliary epithelium.
Experimental eye research 1993;56(6):659-69.
1992: Hernando N; Martín-Alonso J M; Ghosh S; Coca-Prados M
Isolation of a cDNA encoding a glutathione S-transferase (GST) class-pi from the bovine ocular ciliary epithelium.
Experimental eye research 1992;55(5):711-8.
1992: Martín-Alonso J M; Hernando N; Ghosh S; Coca-Prados M
Molecular cloning of the bovine CD9 antigen from ocular ciliary epithelial cells.
Journal of biochemistry 1992;112(1):63-7.
1992: Coca-Prados M; Ghosh S; Gilula N B; Kumar N M
Expression and cellular distribution of the alpha 1 gap junction gene product in the ocular pigmented ciliary epithelium.
Current eye research 1992;11(2):113-22.
1991: Ghosh S; Hernando N; Martín-Alonso J M; Martin-Vasallo P; Coca-Prados M
Expression of multiple Na+,K(+)-ATPase genes reveals a gradient of isoforms along the nonpigmented ciliary epithelium: functional implications in aqueous humor secretion.
Journal of cellular physiology 1991;149(2):184-94.
1990: Ghosh S; Freitag A C; Martin-Vasallo P; Coca-Prados M
Cellular distribution and differential gene expression of the three alpha subunit isoforms of the Na,K-ATPase in the ocular ciliary epithelium.
The Journal of biological chemistry 1990;265(5):2935-40.
1989: Dotto G P; Moellmann G; Ghosh S; Edwards M; Halaban R
Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment.
The Journal of cell biology 1989;109(6 Pt 1):3115-28.
1989: Martin-Vasallo P; Ghosh S; Coca-Prados M
Expression of Na,K-ATPase alpha subunit isoforms in the human ciliary body and cultured ciliary epithelial cells.
Journal of cellular physiology 1989;141(2):243-52.
1988: Halaban R; Kwon B S; Ghosh S; Delli Bovi P; Baird A
bFGF as an autocrine growth factor for human melanomas.
Oncogene research 1988;3(2):177-86.

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