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Jean-Marie Ghuysen

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Colette Goffin; Jean-Marie Ghuysen
Biochemistry and comparative genomics of SxxK superfamily acyltransferases offer a clue to the mycobacterial paradox: presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent.
M Marrec-Fairley; André Piette; X Gallet; Robert Brasseur; H Hara; Claudine Fraipont; Jean-Marie Ghuysen; Martine Nguyen-Distèche
Differential functionalities of amphiphilic peptide segments of the cell-septation penicillin-binding protein 3 of Escherichia coli.
Mohammed Terrak; Tushar Ghosh; Jean Van Heijenoort; Jozef Van Beeumen; Maxime Lampilas; Jozsef Aszodi; Juan A Ayala; Jean-Marie Ghuysen; Martine Nguyen-Distèche
The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan-polymerizing penicillin-binding protein 1b of Escherichia coli.

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2002: Colette Goffin; Jean-Marie Ghuysen
Biochemistry and comparative genomics of SxxK superfamily acyltransferases offer a clue to the mycobacterial paradox: presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent.
Microbiology and molecular biology reviews : MMBR 2002;66(4):702-38, table of contents.
2000: M Marrec-Fairley; André Piette; X Gallet; Robert Brasseur; H Hara; Claudine Fraipont; Jean-Marie Ghuysen; Martine Nguyen-Distèche
Differential functionalities of amphiphilic peptide segments of the cell-septation penicillin-binding protein 3 of Escherichia coli.
Molecular microbiology 2000;37(5):1019-31.
1999: Mohammed Terrak; Tushar Ghosh; Jean Van Heijenoort; Jozef Van Beeumen; Maxime Lampilas; Jozsef Aszodi; Juan A Ayala; Jean-Marie Ghuysen; Martine Nguyen-Distèche
The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan-polymerizing penicillin-binding protein 1b of Escherichia coli.
Molecular microbiology 1999;34(2):350-64.
1999: Jean-Marie Ghuysen; Colette Goffin
Lack of cell wall peptidoglycan versus penicillin sensitivity: new insights into the chlamydial anomaly.
Antimicrobial agents and chemotherapy 1999;43(10):2339-44.
1998: Colette Goffin; Jean-Marie Ghuysen
Multimodular penicillin-binding proteins: an enigmatic family of orthologs and paralogs.
Microbiology and molecular biology reviews : MMBR 1998;62(4):1079-93.
1998: D Raze; Olivier Dardenne; S Hallut; M Martinez-Bueno; Jacques Coyette; Jean-Marie Ghuysen
The gene encoding the low-affinity penicillin-binding protein 3r in Enterococcus hirae S185R is borne on a plasmid carrying other antibiotic resistance determinants.
Antimicrobial agents and chemotherapy 1998;42(3):534-9.
1998: Colette Duez; Iris Thamm; Frédéric Sapunaric; Jacques Coyette; Jean-Marie Ghuysen
The division and cell wall gene cluster of Enterococcus hirae S185.
DNA sequence : the journal of DNA sequencing and mapping 1998;9(3):149-61.
1998: Jean-Marie Ghuysen
[The bacterial cell wall and penicillin resistance: facts, questions and hopes].
Bulletin et mémoires de l'Académie royale de médecine de Belgique 1998;153(4):235-41.
1998: Jean-Marie Ghuysen
[Bacterial resistance to antibiotics, an exemplary model of directed molecular evolution].
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1998;60(4):287-94.
1997: G H Zhao; Colette Duez; Sophie Lepage; C Forceille; Noureddine Rhazi; D Klein; Jean-Marie Ghuysen; Jean-Marie Frère
Site-directed mutagenesis of the Actinomadura R39 DD-peptidase.
The Biochemical journal 1997;327 ( Pt 2)():377-81.
1997: M Adam; Claudine Fraipont; Noureddine Rhazi; Martine Nguyen-Distèche; Bernard Lakaye; Jean-Marie Frère; Bart Devreese; Jozef Van Beeumen; Y van Heijenoort; Jean Van Heijenoort; Jean-Marie Ghuysen
The bimodular G57-V577 polypeptide chain of the class B penicillin-binding protein 3 of Escherichia coli catalyzes peptide bond formation from thiolesters and does not catalyze glycan chain polymerization from the lipid II intermediate.
Journal of bacteriology 1997;179(19):6005-9.
1997: Sophie Lepage; P Dubois; Tushar Ghosh; Bernard Joris; S Mahapatra; M Kundu; J Basu; P Chakrabarti; S T Cole; Martine Nguyen-Distèche; Jean-Marie Ghuysen
Dual multimodular class A penicillin-binding proteins in Mycobacterium leprae.
Journal of bacteriology 1997;179(14):4627-30.
1997: Karin Hardt; Bernard Joris; Sophie Lepage; Robert Brasseur; J O Lampen; Jean-Marie Frère; Anthony L Fink; Jean-Marie Ghuysen
The penicillin sensory transducer, BlaR, involved in the inducibility of beta-lactamase synthesis in Bacillus licheniformis is embedded in the plasma membrane via a four-alpha-helix bundle.
Molecular microbiology 1997;23(5):935-44.
1997: Jean-Marie Ghuysen
Penicillin-binding proteins. Wall peptidoglycan assembly and resistance to penicillin: facts, doubts and hopes.
International journal of antimicrobial agents 1997;8(1):45-60.
1996: F Chavagnat; Colette Duez; M Guinand; Philippe Potin; Tristan Barbeyron; Bernard Henrissat; Jean Wallach; Jean-Marie Ghuysen
Cloning, sequencing and overexpression in Escherichia coli of the alginatelyase-encoding aly gene of Pseudomonas alginovora: identification of three classes of alginate lyases.
The Biochemical journal 1996;319 ( Pt 2)():575-83.
1996: Colette Goffin; Claudine Fraipont; J Ayala; M Terrak; Martine Nguyen-Distèche; Jean-Marie Ghuysen
The non-penicillin-binding module of the tripartite penicillin-binding protein 3 of Escherichia coli is required for folding and/or stability of the penicillin-binding module and the membrane-anchoring module confers cell septation activity on the folded structure.
Journal of bacteriology 1996;178(18):5402-9.
1996: M E Mollerach; P Partoune; Jacques Coyette; Jean-Marie Ghuysen
Importance of the E-46-D-160 polypeptide segment of the non-penicillin-binding module for the folding of the low-affinity, multimodular class B penicillin-binding protein 5 of Enterococus hirae.
Journal of bacteriology 1996;178(6):1774-5.
1996: Joyoti Basu; S Mahapatra; Manikuntala Kundu; S Mukhopadhyay; Martine Nguyen-Distèche; P Dubois; Bernard Joris; J Van Beeumen; S T Cole; Parul Chakrabarti; Jean-Marie Ghuysen
Identification and overexpression in Escherichia coli of a Mycobacterium leprae gene, pon1, encoding a high-molecular-mass class A penicillin-binding protein, PBP1.
Journal of bacteriology 1996;178(6):1707-11.
1996: Jean-Marie Ghuysen; Paulette Charlier; Jacques Coyette; Colette Duez; Eveline Fonzé; Claudine Fraipont; Colette Goffin; Bernard Joris; Martine Nguyen-Distèche
Penicillin and beyond: evolution, protein fold, multimodular polypeptides, and multiprotein complexes.
Microbial drug resistance (Larchmont, N.Y.) 1996;2(2):163-75.
1995: J Grandchamps; Martine Nguyen-Distèche; C Damblon; Jean-Marie Frère; Jean-Marie Ghuysen
Streptomyces K15 active-site serine DD-transpeptidase: specificity profile for peptide, thiol ester and ester carbonyl donors and pathways of the transfer reactions.
The Biochemical journal 1995;307 ( Pt 2)():335-9.
1995: M Malissard; F Chavagnat; Colette Duez; M J Vacheron; M Guinand; G Michel; Jean-Marie Ghuysen
Overproduction and properties of the mannuronate alginate lyase AlxMB.
FEMS microbiology letters 1995;126(2):105-11.
1994: Jean-Marie Ghuysen
Molecular structures of penicillin-binding proteins and beta-lactamases.
Trends in microbiology 1994;2(10):372-80.
1994: Colette Duez; C Piron-Fraipont; Bernard Joris; Jean Dusart; M S Urdea; J A Martial; Jean-Marie Frère; Jean-Marie Ghuysen
Primary structure of the Streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene.
European journal of biochemistry / FEBS 1994;224(3):1079.
1994: L Fanuel; B Granier; J M Wilkin; C Bellefroid-Bourguignon; Bernard Joris; J Knowles; E Komives; J Van Beeumen; Jean-Marie Ghuysen; Jean-Marie Frère
The precursor of the Streptomyces R61 DD-peptidase containing a C-terminal extension is inactive.
FEBS letters 1994;351(1):49-52.
1994: J Ayala; Colette Goffin; Martine Nguyen-Distèche; Jean-Marie Ghuysen
Site-directed mutagenesis of penicillin-binding protein 3 of Escherichia coli: role of Val-545.
FEMS microbiology letters 1994;121(2):251-6.
1994: Jean-Marie Ghuysen; Josette Lamotte-Brasseur; Bernard Joris; G D Shockman
Binding site-shaped repeated sequences of bacterial wall peptidoglycan hydrolases.
FEBS letters 1994;342(1):23-8.
1994: Claudine Fraipont; M Adam; Martine Nguyen-Distèche; W Keck; J Van Beeumen; Juan A Ayala; B Granier; H Hara; Jean-Marie Ghuysen
Engineering and overexpression of periplasmic forms of the penicillin-binding protein 3 of Escherichia coli.
The Biochemical journal 1994;298 ( Pt 1)():189-95.
1993: Colette Goffin; Juan A Ayala; Martine Nguyen-Distèche; Jean-Marie Ghuysen
Site-directed mutagenesis of dicarboxylic acid residues of the penicillin-binding module of the Escherichia coli penicillin-binding protein 3.
FEMS microbiology letters 1993;113(3):247-51.
1993: M L Hourdou; M Guinand; M J Vacheron; G Michel; L Denoroy; Colette Duez; S Englebert; Bernard Joris; G Weber; Jean-Marie Ghuysen
Characterization of the sporulation-related gamma-D-glutamyl-(L)meso-diaminopimelic-acid-hydrolysing peptidase I of Bacillus sphaericus NCTC 9602 as a member of the metallo(zinc) carboxypeptidase A family. Modular design of the protein.
The Biochemical journal 1993;292 ( Pt 2)():563-70.
1993: M Malissard; Colette Duez; M Guinand; M J Vacheron; G Michel; Nicole Marty; Bernard Joris; Iris Thamm; Jean-Marie Ghuysen
Sequence of a gene encoding a (poly ManA) alginate lyase active on Pseudomonas aeruginosa alginate.
FEMS microbiology letters 1993;110(1):101-6.
1993: G Piras; D Raze; A el Kharroubi; D Hastir; S Englebert; Jacques Coyette; Jean-Marie Ghuysen
Cloning and sequencing of the low-affinity penicillin-binding protein 3r-encoding gene of Enterococcus hirae S185: modular design and structural organization of the protein.
Journal of bacteriology 1993;175(10):2844-52.
1992: P Palomeque-Messia; V Quittre; M Leyh-Bouille; Martine Nguyen-Distèche; C J Gershater; I K Dacey; Jean Dusart; J Van Beeumen; Jean-Marie Ghuysen
Secretion by overexpression and purification of the water-soluble Streptomyces K15 DD-transpeptidase/penicillin-binding protein.
The Biochemical journal 1992;288 ( Pt 1)():87-91.
1992: Y Zhu; S Englebert; Bernard Joris; Jean-Marie Ghuysen; T Kobayashi; J O Lampen
Structure, function, and fate of the BlaR signal transducer involved in induction of beta-lactamase in Bacillus licheniformis.
Journal of bacteriology 1992;174(19):6171-8.
1992: B Granier; Colette Duez; Sophie Lepage; S Englebert; Jean Dusart; Otto Dideberg; J Van Beeumen; Jean-Marie Frère; Jean-Marie Ghuysen
Primary and predicted secondary structure of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.
The Biochemical journal 1992;286 ( Pt 3)():981-2.
1992: A M Hadonou; J M Wilkin; L Varetto; Bernard Joris; Josette Lamotte-Brasseur; D Klein; Colette Duez; Jean-Marie Ghuysen; Jean-Marie Frère
Site-directed mutagenesis of the Streptomyces R61 DD-peptidase. Catalytic function of the conserved residues around the active site and a comparison with class-A and class-C beta-lactamases.
European journal of biochemistry / FEBS 1992;207(1):97-102.
1992: C Bourguignon-Bellefroid; Bernard Joris; J Van Beeumen; Jean-Marie Ghuysen; Jean-Marie Frère
Point mutations of two arginine residues in the Streptomyces R61 DD-peptidase.
The Biochemical journal 1992;283 ( Pt 1)():123-8.
1992: B Granier; Colette Duez; Sophie Lepage; S Englebert; Jean Dusart; Otto Dideberg; J Van Beeumen; Jean-Marie Frère; Jean-Marie Ghuysen
Primary and predicted secondary structures of the Actinomadura R39 extracellular DD-peptidase, a penicillin-binding protein (PBP) related to the Escherichia coli PBP4.
The Biochemical journal 1992;282 ( Pt 3)():781-8.
1992: Bernard Joris; S Englebert; C P Chu; R Kariyama; Lolita Daneo-Moore; G D Shockman; Jean-Marie Ghuysen
Modular design of the Enterococcus hirae muramidase-2 and Streptococcus faecalis autolysin.
FEMS microbiology letters 1992;70(3):257-64.
1992: M L Hourdou; Colette Duez; Bernard Joris; M J Vacheron; M Guinand; G Michel; Jean-Marie Ghuysen
Cloning and nucleotide sequence of the gene encoding the gamma-D-glutamyl-L-diamino acid endopeptidase II of Bacillus sphaericus.
FEMS microbiology letters 1992;70(2):165-70.
1992: A M Hadonou; M Jamin; M Adam; Bernard Joris; Jean Dusart; Jean-Marie Ghuysen; Jean-Marie Frère
Importance of the His-298 residue in the catalytic mechanism of the Streptomyces R61 extracellular DD-peptidase.
The Biochemical journal 1992;282 ( Pt 2)():495-500.
1992: C Bourguignon-Bellefroid; J M Wilkin; Bernard Joris; R T Aplin; C Houssier; F G Prendergast; J Van Beeumen; Jean-Marie Ghuysen; Jean-Marie Frère
Importance of the two tryptophan residues in the Streptomyces R61 exocellular DD-peptidase.
The Biochemical journal 1992;282 ( Pt 2)():361-7.
1992: Josette Lamotte-Brasseur; F Jacob-Dubuisson; Georges Dive; Jean-Marie Frère; Jean-Marie Ghuysen
Streptomyces albus G serine beta-lactamase. Probing of the catalytic mechanism via molecular modelling of mutant enzymes.
The Biochemical journal 1992;282 ( Pt 1)():189-95.
1991: A el Kharroubi; Philippe Jacques; G Piras; J Van Beeumen; Jacques Coyette; Jean-Marie Ghuysen
The Enterococcus hirae R40 penicillin-binding protein 5 and the methicillin-resistant Staphylococcus aureus penicillin-binding protein 2' are similar.
The Biochemical journal 1991;280 ( Pt 2)():463-9.
1991: Bernard Joris; Philippe Ledent; Otto Dideberg; Eveline Fonzé; Josette Lamotte-Brasseur; J A Kelly; Jean-Marie Ghuysen; Jean-Marie Frère
Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins.
Antimicrobial agents and chemotherapy 1991;35(11):2294-301.
1991: P Palomeque-Messia; S Englebert; M Leyh-Bouille; Martine Nguyen-Distèche; Colette Duez; S Houba; Otto Dideberg; J Van Beeumen; Jean-Marie Ghuysen
Amino acid sequence of the penicillin-binding protein/DD-peptidase of Streptomyces K15. Predicted secondary structures of the low Mr penicillin-binding proteins of class A.
The Biochemical journal 1991;279 ( Pt 1)():223-30.
1991: Josette Lamotte-Brasseur; Georges Dive; Otto Dideberg; Paulette Charlier; Jean-Marie Frère; Jean-Marie Ghuysen
Mechanism of acyl transfer by the class A serine beta-lactamase of Streptomyces albus G.
The Biochemical journal 1991;279 ( Pt 1)():213-21.
1991: Philippe Jacques; A el Kharroubi; J Van Beeumen; G Piras; Jacques Coyette; Jean-Marie Ghuysen
Mode of membrane insertion and sequence of a 32-amino acid peptide stretch of the penicillin-binding protein 4 of Enterococcus hirae.
FEMS microbiology letters 1991;66(2):119-23.
1991: Jean-Marie Ghuysen
Serine beta-lactamases and penicillin-binding proteins.
Annual review of microbiology 1991;45():37-67.
1990: G Piras; A el Kharroubi; J van Beeumen; E Coeme; Jacques Coyette; Jean-Marie Ghuysen
Characterization of an Enterococcus hirae penicillin-binding protein 3 with low penicillin affinity.
Journal of bacteriology 1990;172(12):6856-62.
1990: H Urabe; M V Lenzini; M Mukaide; Jean Dusart; Michiko M Nakano; Jean-Marie Ghuysen; H Ogawara
Beta-lactamase expression in Streptomyces cacaoi.
Journal of bacteriology 1990;172(11):6427-34.
1990: Jean-Marie Ghuysen
Membrane topology, structure, and functions of the penicillin-interactive proteins.
Biotechnology and applied biochemistry 1990;12(5):468-72.
1990: F Jacob; Bernard Joris; Otto Dideberg; Jean Dusart; Jean-Marie Ghuysen; Jean-Marie Frère
Engineering a novel beta-lactamase by a single point mutation.
Protein engineering 1990;4(1):79-86.
1990: Colette Duez; Bernard Lakaye; S Houba; Jean Dusart; Jean-Marie Ghuysen
Cloning, nucleotide sequence and amplified expression of the gene encoding the extracellular metallo (Zn) DD-peptidase of Streptomyces albus G.
FEMS microbiology letters 1990;59(1-2):215-9.
1990: C Piron-Fraipont; M V Lenzini; Jean Dusart; Jean-Marie Ghuysen
Transcriptional analysis of the DD-peptidase/penicillin-binding protein-encoding dac gene of Streptomyces R61: use of the promoter and signal sequences in a secretion vector.
Molecular & general genetics : MGG 1990;223(1):114-20.
1990: Josette Lamotte-Brasseur; Georges Dive; D Dehareng; Jean-Marie Ghuysen
Electrostatic potential maps at the quantum chemistry level of the active sites of the serine peptidases, alpha-chymotrypsin and subtilisin.
Journal of theoretical biology 1990;145(2):183-98.
1990: Bernard Joris; Philippe Ledent; T Kobayashi; J O Lampen; Jean-Marie Ghuysen
Expression in Escherichia coli of the carboxy terminal domain of the BLAR sensory-transducer protein of Bacillus licheniformis as a water-soluble Mr 26,000 penicillin-binding protein.
FEMS microbiology letters 1990;58(1):107-13.
1990: Bernard Joris; Georges Dive; Adriano O Henriques; P J Piggot; Jean-Marie Ghuysen
The life-cycle proteins RodA of Escherichia coli and SpoVE of Bacillus subtilis have very similar primary structures.
Molecular microbiology 1990;4(3):513-7.
1990: Y F Zhu; I H Curran; Bernard Joris; Jean-Marie Ghuysen; J O Lampen
Identification of BlaR, the signal transducer for beta-lactamase production in Bacillus licheniformis, as a penicillin-binding protein with strong homology to the OXA-2 beta-lactamase (class D) of Salmonella typhimurium.
Journal of bacteriology 1990;172(2):1137-41.
1989: S Houba; S Willem; Colette Duez; C Molitor; Jean Dusart; Jean-Marie Frère; Jean-Marie Ghuysen
Nucleotide sequence of the gene encoding the active-site serine beta-lactamase from Actinomadura R39.
FEMS microbiology letters 1989;53(3):241-6.
1989: C Piron-Fraipont; Colette Duez; Alain Matagne; C Molitor; Jean Dusart; Jean-Marie Frère; Jean-Marie Ghuysen
Cloning and amplified expression in Streptomyces lividans of the gene encoding the extracellular beta-lactamase of Actinomadura R39.
The Biochemical journal 1989;262(3):849-54.
1989: A el Kharroubi; G Piras; Philippe Jacques; I Szabo; J Van Beeumen; Jacques Coyette; Jean-Marie Ghuysen
Active-site and membrane topology of the DD-peptidase/penicillin-binding protein no. 6 of Enterococcus hirae (Streptococcus faecium) A.T.C.C. 9790.
The Biochemical journal 1989;262(2):457-62.
1989: M Leyh-Bouille; J Van Beeumen; S Renier-Pirlot; Bernard Joris; Martine Nguyen-Distèche; Jean-Marie Ghuysen
The Streptomyces K15 DD-peptidase/penicillin-binding protein. Active site and sequence of the N-terminal region.
The Biochemical journal 1989;260(2):601-4.
1988: Jean-Marie Ghuysen
Bacterial active-site serine penicillin-interactive proteins and domains: mechanism, structure, and evolution.
Reviews of infectious diseases 1988;10(4):726-32.
1988: J B Belder; Martine Nguyen-Distèche; N Houba-Herin; Jean-Marie Ghuysen; I N Maruyama; H Hara; Y Hirota; M Inouye
Overexpression, solubilization and refolding of a genetically engineered derivative of the penicillin-binding protein 3 of Escherichia coli K12.
Molecular microbiology 1988;2(4):519-25.
1988: J A Kelly; James R Knox; P C Moews; J M Frere; Jean-Marie Ghuysen
Using X-ray diffraction results and computer graphics to design beta-lactams.
Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1988;62 Suppl():182-91.
1988: Bernard Joris; Jean-Marie Ghuysen; Georges Dive; A Renard; Otto Dideberg; Paulette Charlier; Jean-Marie Frère; J A Kelly; J C Boyington; P C Moews
The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family.
The Biochemical journal 1988;250(2):313-24.
1987: L Varetto; Jean-Marie Frère; Jean-Marie Ghuysen
The importance of the negative charge of beta-lactam compounds for the inactivation of the active-site serine DD-peptidase of Streptomyces R61.
FEBS letters 1987;225(1-2):218-22.
1987: M V Lenzini; S Nojima; Jean Dusart; H Ogawara; P Dehottay; Jean-Marie Frere; Jean-Marie Ghuysen
Cloning and amplified expression in Streptomyces lividans of the gene encoding the extracellular beta-lactamase from Streptomyces cacaoi.
Journal of general microbiology 1987;133(10):2915-20.
1987: Otto Dideberg; Paulette Charlier; J P Wéry; P Dehottay; Jean Dusart; T Erpicum; Jean-Marie Frère; Jean-Marie Ghuysen
The crystal structure of the beta-lactamase of Streptomyces albus G at 0.3 nm resolution.
The Biochemical journal 1987;245(3):911-3.
1987: P Dehottay; Jean Dusart; F De Meester; Bernard Joris; J Van Beeumen; T Erpicum; Jean-Marie Frère; Jean-Marie Ghuysen
Nucleotide sequence of the gene encoding the Streptomyces albus G beta-lactamase precursor.
European journal of biochemistry / FEBS 1987;166(2):345-50.
1987: F De Meester; Bernard Joris; M V Lenzini; P Dehottay; T Erpicium; Jean Dusart; D Klein; Jean-Marie Ghuysen; Jean-Marie Frère; J Van Beeumen
The active sites of the beta-lactamases of Streptomyces cacaoi and Streptomyces albus G.
The Biochemical journal 1987;244(2):427-32.
1987: Colette Duez; C Piron-Fraipont; Bernard Joris; Jean Dusart; M S Urdea; J A Martial; Jean-Marie Frère; Jean-Marie Ghuysen
Primary structure of the Streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene.
European journal of biochemistry / FEBS 1987;162(3):509-18.
1987: M Leyh-Bouille; Martine Nguyen-Distèche; C Bellefroid-Bourguignon; Jean-Marie Ghuysen
Effects of thiol reagents on Streptomyces K15 DD-peptidase-catalysed reactions.
The Biochemical journal 1987;241(3):893-7.
1986: M Leyh-Bouille; Martine Nguyen-Distèche; S Pirlot; A Veithen; C Bourguignon; Jean-Marie Ghuysen
Streptomyces K15 DD-peptidase-catalysed reactions with suicide beta-lactam carbonyl donors.
The Biochemical journal 1986;235(1):177-82.
1986: Jean-Marie Ghuysen; Jean-Marie Frère; M Leyh-Bouille; Martine Nguyen-Distèche; Jacques Coyette
Active-site-serine D-alanyl-D-alanine-cleaving-peptidase-catalysed acyl-transfer reactions. Procedures for studying the penicillin-binding proteins of bacterial plasma membranes.
The Biochemical journal 1986;235(1):159-65.
1986: Martine Nguyen-Distèche; M Leyh-Bouille; S Pirlot; Jean-Marie Frère; Jean-Marie Ghuysen
Streptomyces K15 DD-peptidase-catalysed reactions with ester and amide carbonyl donors.
The Biochemical journal 1986;235(1):167-76.
1986: P Dehottay; Jean Dusart; Colette Duez; M V Lenzini; J A Martial; Jean-Marie Frère; Jean-Marie Ghuysen; T Kieser
Cloning and amplified expression in Streptomyces lividans of a gene encoding extracellular beta-lactamase from Streptomyces albus G.
Gene 1986;42(1):31-6.
1985: J A Kelly; James R Knox; P C Moews; G J Hite; J B Bartolone; H Zhao; Bernard Joris; Jean-Marie Frère; Jean-Marie Ghuysen
2.8-A Structure of penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase from Streptomyces R61 and complexes with beta-lactams.
The Journal of biological chemistry 1985;260(10):6449-58.
1984: Paulette Charlier; Otto Dideberg; J C Jamoulle; Jean-Marie Frère; Jean-Marie Ghuysen; Georges Dive; Josette Lamotte-Brasseur
Active-site-directed inactivators of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase of Streptomyces albus G.
The Biochemical journal 1984;219(3):763-72.
1984: Jean-Marie Ghuysen; Jean-Marie Frère; M Leyh-Bouille; Martine Nguyen-Distèche; Jacques Coyette; Jean Dusart; Bernard Joris; Colette Duez; Otto Dideberg; Paulette Charlier
Bacterial wall peptidoglycan, DD-peptidases and beta-lactam antibiotics.
Scandinavian journal of infectious diseases. Supplementum 1984;42():17-37.
1982: J A Kelly; P C Moews; James R Knox; Jean-Marie Frère; Jean-Marie Ghuysen
Penicillin target enzyme and the antibiotic binding site.
Science (New York, N.Y.) 1982;218(4571):479-81.
1982: Martine Nguyen-Distèche; M Leyh-Bouille; Jean-Marie Ghuysen
Isolation of the membrane-bound 26 000-Mr penicillin-binding protein of Streptomyces strain K15 in the form of a penicillin-sensitive D-alanyl-D-alanine-cleaving transpeptidase.
The Biochemical journal 1982;207(1):109-15.
1982: Otto Dideberg; Paulette Charlier; Georges Dive; Bernard Joris; Jean-Marie Frère; Jean-Marie Ghuysen
Structure of a Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase at 2.5 A resolution.
Nature 1982;299(5882):469-70.
1981: M Leyh-Bouille; Martine Nguyen-Distèche; Jean-Marie Ghuysen
On the DD-carboxypeptidase enzyme system of Streptomyces strain K15.
European journal of biochemistry / FEBS 1981;115(3):579-84.
1980: Otto Dideberg; Bernard Joris; Jean-Marie Frere; Jean-Marie Ghuysen; G Weber; R Robaye; J M Delbrouck; I Roelandts
The exocellular DD-carboxypeptidase of Streptomyces albus G: a metallo (Zn2+) enzyme.
FEBS letters 1980;117(1):215-8.
1980: Otto Dideberg; Paulette Charlier; L Dupont; M Vermeire; Jean-Marie Frere; Jean-Marie Ghuysen
The 4.5 A resolution structure analysis of the exocellular DD-carboxypeptidase of Streptomyces albus G.
FEBS letters 1980;117(1):212-4.
1980: Jean Dusart; M Leyh-Bouille; Martine Nguyen-Distèche; Jean-Marie Ghuysen; P E Reynolds
Penicillin-binding proteins in the membranes of Streptomyces sp [proceedings].
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