FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Norbert Ghyselinck

Research Profile

Chemicals & Drugs

Living Beings

Physiology

Procedures

In Situ Hybridization

Co-author Network

Publications

TOP 3
Mathilde Raverdeau; Manuel Mark; Gérard Benoit; Pierre Chambon; Irwin Davidson; Christine Dennefeld; Betty Féret; Aurore Gely-Pernot; Norbert B Ghyselinck
Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.
Daniel C Berry; Colleen M Croniger; Norbert B Ghyselinck; Noa Noy
Transthyretin blocks retinol uptake and cell signaling by the holo-retinol-binding protein receptor STRA6.
Rowena Lavery; Manuel Mark; Eva Pauper; Andreas Schedl; Anne-Amandine Chassot; Dirk G de Rooij; Norbert B Ghyselinck; Elodie P Gregoire; Muriel Klopfenstein; Marie-Christine Chaboissier
Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Norbert Ghyselinck (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Mathilde Raverdeau; Manuel Mark; Gérard Benoit; Pierre Chambon; Irwin Davidson; Christine Dennefeld; Betty Féret; Aurore Gely-Pernot; Norbert B Ghyselinck
Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(41):16582-7.
2012: Daniel C Berry; Colleen M Croniger; Norbert B Ghyselinck; Noa Noy
Transthyretin blocks retinol uptake and cell signaling by the holo-retinol-binding protein receptor STRA6.
Molecular and cellular biology 2012;32(19):3851-9.
2012: Rowena Lavery; Manuel Mark; Eva Pauper; Andreas Schedl; Anne-Amandine Chassot; Dirk G de Rooij; Norbert B Ghyselinck; Elodie P Gregoire; Muriel Klopfenstein; Marie-Christine Chaboissier
Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals.
PLoS genetics 2012;8(12):e1003170.
2012: Alberto Ruiz; Chinatsu Tosha; Norbert B Ghyselinck; Samer Habib; Jane Hu; Hugues Jacobs; Muriel Klopfenstein; Marcia Lloyd; Manuel Mark; Steven Nusinowitz; Roxana A Radu; Dean Bok
Retinoid content, visual responses, and ocular morphology are compromised in the retinas of mice lacking the retinol-binding protein receptor, STRA6.
Investigative ophthalmology & visual science 2012;53(6):3027-39.
2011: Hugues Jacobs; Manuel Mark; Matti Viluksela; Christine Dennefeld; Betty Féret; Helen Håkansson; Norbert B Ghyselinck
Retinoic acid drives aryl hydrocarbon receptor expression and is instrumental to dioxin-induced toxicity during palate development.
Environmental health perspectives 2011;119(11):1590-5.
2011: Gonzalo Fernández-Miranda; Norbert B Ghyselinck; Alejandra González; Javier Martín; Sagrario Ortega; Marianna Trakala; Ignacio Pérez de Castro; Marta Cañamero; Beatriz Escobar; Marcos Malumbres
Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development.
Development (Cambridge, England) 2011;138(13):2661-72.
2011: Radhika Puttagunta; André Schmandke; Elisa Floriddia; Natalie Fomin; Perrine Gaub; Norbert B Ghyselinck; Simone Di Giovanni
RA-RAR-β counteracts myelin-dependent inhibition of neurite outgrowth via Lingo-1 repression.
The Journal of cell biology 2011;193(7):1147-56.
2010: Laura Cammas; Frédéric Trensz; Abdeljalil Jellali; Norbert B Ghyselinck; Michel J Roux; Pascal Dollé
Retinoic acid receptor (RAR)-alpha is not critically required for mediating retinoic acid effects in the developing mouse retina.
Investigative ophthalmology & visual science 2010;51(6):3281-90.
2009: Emilie A Leclerc; Anne Huchenq; Nicolas R Mattiuzzo; Daniel Metzger; Pierre Chambon; Norbert B Ghyselinck; Guy Serre; Nathalie Jonca; Marina Guerrin
Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction.
Journal of cell science 2009;122(Pt 15):2699-709.
2009: Bénédicte Mascrez; Norbert B Ghyselinck; Pierre Chambon; Manuel Mark
A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(11):4272-7.
2009: Manuel Mark; Norbert B Ghyselinck; Pierre Chambon
Function of retinoic acid receptors during embryonic development.
Nuclear receptor signaling 2009;7():e002.
2008: Nadege vernet; Christine Dennefeld; Muriel Klopfenstein; Alberto Ruiz; Dean Bok; Norbert B Ghyselinck; Manuel Mark
Retinoid X receptor beta (RXRB) expression in Sertoli cells controls cholesterol homeostasis and spermiation.
Reproduction (Cambridge, England) 2008;136(5):619-26.
2008: Manuel Mark; Hugues Jacobs; Mustapha Oulad-Abdelghani; Christine Dennefeld; Betty Féret; Nadege vernet; Carmen-Alina Codreanu; Pierre Chambon; Norbert B Ghyselinck
STRA8-deficient spermatocytes initiate, but fail to complete, meiosis and undergo premature chromosome condensation.
Journal of cell science 2008;121(Pt 19):3233-42.
2008: Nicolas Matt; Norbert B Ghyselinck; Isabelle Pellerin; Valérie Dupé
Impairing retinoic acid signalling in the neural crest cells is sufficient to alter entire eye morphogenesis.
Developmental biology 2008;320(1):140-8.
2008: Wen-Lin Liao; Hsiu-Chao Tsai; Hsiao-Fang Wang; Josephine Chang; Kuan-Ming Lu; Hsiao-Lin Wu; Yi-Chao Lee; Ting-Fen Tsai; Hiroshi Takahashi; Michael Wagner; Norbert B Ghyselinck; Pierre Chambon; Fu-Chin Liu
Modular patterning of structure and function of the striatum by retinoid receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(18):6765-70.
2007: Mehdi Tafti; Norbert B Ghyselinck
Functional implication of the vitamin A signaling pathway in the brain.
Archives of neurology 2007;64(12):1706-11.
2007: Alberto Ruiz; Norbert B Ghyselinck; Nathan L Mata; Steven Nusinowitz; Marcia Lloyd; Christine Dennefeld; Pierre Chambon; Dean Bok
Somatic ablation of the Lrat gene in the mouse retinal pigment epithelium drastically reduces its retinoid storage.
Investigative ophthalmology & visual science 2007;48(12):5377-87.
2007: Sophie Vauclair; François Majo; André-Dante Durham; Norbert B Ghyselinck; Yann Barrandon; Freddy Radtke
Corneal epithelial cell fate is maintained during repair by Notch1 signaling via the regulation of vitamin A metabolism.
Developmental cell 2007;13(2):242-53.
2007: Frank Schnütgen; Norbert B Ghyselinck
Adopting the good reFLEXes when generating conditional alterations in the mouse genome.
Transgenic research 2007;16(4):405-13.
2007: Aida Halilagic; VANESSA RIBES; Norbert B Ghyselinck; Maija H Zile; Pascal Dollé; Michèle Studer
Retinoids control anterior and dorsal properties in the developing forebrain.
Developmental biology 2007;303(1):362-75.
2006: Nadege vernet; Christine Dennefeld; Florian Guillou; Pierre Chambon; Norbert B Ghyselinck; Manuel Mark
Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells.
The EMBO journal 2006;25(24):5816-25.
2006: Cécile Calléja; Nadia Messaddeq; Benoit Chapellier; Haiyuan Yang; Wojciech Krezel; Mei Li; Daniel Metzger; Bénédicte Mascrez; Kiminori Ohta; Hiroyuki Kagechika; Yasuyuki Endo; Manuel Mark; Norbert B Ghyselinck; Pierre Chambon
Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes.
Genes & development 2006;20(11):1525-38.
2006: Norbert B Ghyselinck; Nadege vernet; Christine Dennefeld; Norbert Giese; Heinz Nau; Pierre Chambon; Stéphane Viville; Manuel Mark
Retinoids and spermatogenesis: lessons from mutant mice lacking the plasma retinol binding protein.
Developmental dynamics : an official publication of the American Association of Anatomists 2006;235(6):1608-22.
2006: Manuel Mark; Norbert B Ghyselinck; Pierre Chambon
Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis.
Annual review of pharmacology and toxicology 2006;46():451-80.
2006: Nadege vernet; Christine Dennefeld; Cécile Rochette-Egly; Mustapha Oulad-Abdelghani; Pierre Chambon; Norbert B Ghyselinck; Manuel Mark
Retinoic acid metabolism and signaling pathways in the adult and developing mouse testis.
Endocrinology 2006;147(1):96-110.
2005: Nicolas Matt; Valérie Dupé; Jean-Marie Garnier; Christine Dennefeld; Pierre Chambon; Manuel Mark; Norbert B Ghyselinck
Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells.
Development (Cambridge, England) 2005;132(21):4789-800.
2005: Stéphanie Maret; Paul Franken; Yves Dauvilliers; Norbert B Ghyselinck; Pierre Chambon; Mehdi Tafti
Retinoic acid signaling affects cortical synchrony during sleep.
Science (New York, N.Y.) 2005;310(5745):111-3.
2005: Pi Hoegberg; Carsten K Schmidt; Nick Fletcher; Charlotte B Nilsson; Christina Trossvik; A Gerlienke Schuur; Abraham Brouwer; Heinz Nau; Norbert B Ghyselinck; Pierre Chambon; Helen Håkansson
Retinoid status and responsiveness to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking retinoid binding protein or retinoid receptor forms.
Chemico-biological interactions 2005;156(1):25-39.
2005: Roseann Piantedosi; Norbert B Ghyselinck; William S Blaner; Silke Vogel
Cellular retinol-binding protein type III is needed for retinoid incorporation into milk.
The Journal of biological chemistry 2005;280(25):24286-92.
2005: Frank Schnütgen; Silke De-Zolt; Petra Van Sloun; Melanie Hollatz; Thomas Floss; Jens Hansen; Joachim Altschmied; Claudia Seisenberger; Norbert B Ghyselinck; Patricia Ruiz; Pierre Chambon; Wolfgang Wurst; Harald von Melchner
Genomewide production of multipurpose alleles for the functional analysis of the mouse genome.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(20):7221-6.
2005: Marta Wietrzych; Hamid Meziane; Anne Sutter; Norbert B Ghyselinck; Paul F Chapman; Pierre Chambon; Wojciech Krezel
Working memory deficits in retinoid X receptor gamma-deficient mice.
Learning & memory (Cold Spring Harbor, N.Y.) 2005;12(3):318-26.
2005: Nicolas Matt; Carsten K Schmidt; Valérie Dupé; Christine Dennefeld; Heinz Nau; Pierre Chambon; Manuel Mark; Norbert B Ghyselinck
Contribution of cellular retinol-binding protein type 1 to retinol metabolism during mouse development.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;233(1):167-76.
2005: Patricia Serpente; Stefan Tümpel; Norbert B Ghyselinck; Karen Niederreither; Leanne M Wiedemann; Pascal Dollé; Pierre Chambon; Carl Schwarz; Alex P Gould
Direct crossregulation between retinoic acid receptor {beta} and Hox genes during hindbrain segmentation.
Development (Cambridge, England) 2005;132(3):503-13.
2005: Eduardo Francisco Farias; David E Ong; Norbert B Ghyselinck; Shigeo Nakajo; Yuvarani S Kuppumbatti; Rafael Mira-Y-Lopez
Cellular retinol-binding protein I, a regulator of breast epithelial retinoic acid receptor activity, cell differentiation, and tumorigenicity.
Journal of the National Cancer Institute 2005;97(1):21-9.
2004: Andrei Molotkov; Norbert B Ghyselinck; Pierre Chambon; Gregg Duester
Opposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradation.
The Biochemical journal 2004;383(Pt 2):295-302.
2004: Manuel Mark; Norbert B Ghyselinck; Pierre Chambon
Retinoic acid signalling in the development of branchial arches.
Current opinion in genetics & development 2004;14(5):591-8.
2004: Bénédicte Mascrez; Norbert B Ghyselinck; Mitsuhiro Watanabe; Jean-Sébastien Annicotte; Pierre Chambon; Johan Auwerx; Manuel Mark
Ligand-dependent contribution of RXRbeta to cholesterol homeostasis in Sertoli cells.
EMBO reports 2004;5(3):285-90.
2003: Valérie Dupé; Nicolas Matt; Jean-Marie Garnier; Pierre Chambon; Manuel Mark; Norbert B Ghyselinck
A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14036-41.
2003: Nicolas Matt; Norbert B Ghyselinck; Olivia Wendling; Pierre Chambon; Manuel Mark
Retinoic acid-induced developmental defects are mediated by RARbeta/RXR heterodimers in the pharyngeal endoderm.
Development (Cambridge, England) 2003;130(10):2083-93.
2003: Frank Schnütgen; Nathalie Doerflinger; Cécile Calléja; Olivia Wendling; Pierre Chambon; Norbert B Ghyselinck
A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse.
Nature biotechnology 2003;21(5):562-5.
2003: Daniel Metzger; Arup Kumar Indra; Mei Li; Benoit Chapellier; Cécile Calleja; Norbert B Ghyselinck; Pierre Chambon
Targeted conditional somatic mutagenesis in the mouse: temporally-controlled knock out of retinoid receptors in epidermal keratinocytes.
Methods in enzymology 2003;364():379-408.
2002: Raymond Romand; Eri Hashino; Pascal Dollé; Jean-Luc Vonesch; Pierre Chambon; Norbert B Ghyselinck
The retinoic acid receptors RARalpha and RARgamma are required for inner ear development.
Mechanisms of development 2002;119(2):213-23.
2002: Benoit Chapellier; Manuel Mark; Nadia Messaddeq; Cécile Calléja; Xavier Warot; Jacques Brocard; Christelle Gérard; Mei Li; Daniel Metzger; Norbert B Ghyselinck; Pierre Chambon
Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled.
The EMBO journal 2002;21(13):3402-13.
2002: John C Saari; Maria Nawrot; Gregory G Garwin; Matthew J Kennedy; James B Hurley; Norbert B Ghyselinck; Pierre Chambon
Analysis of the visual cycle in cellular retinol-binding protein type I (CRBPI) knockout mice.
Investigative ophthalmology & visual science 2002;43(6):1730-5.
2002: Norbert B Ghyselinck; Benoit Chapellier; Cécile Calléja; A Kumar Indra; Mei Li; Nadia Messaddeq; Manuel Mark; Daniel Metzger; Pierre Chambon
[Genetic dissection of retinoic acid function in epidermis physiology].
Annales de dermatologie et de vénéréologie 2002;129(5 Pt 2):793-9.
2002: Benoit Chapellier; Manuel Mark; Jean-Marie Garnier; Andrée Dierich; Pierre Chambon; Norbert B Ghyselinck
A conditional floxed (loxP-flanked) allele for the retinoic acid receptor gamma (RARgamma) gene.
Genesis (New York, N.Y. : 2000) 2002;32(2):95-8.
2002: Benoit Chapellier; Manuel Mark; Julie Bastien; Andrée Dierich; Marianne LeMeur; Pierre Chambon; Norbert B Ghyselinck
A conditional floxed (loxP-flanked) allele for the retinoic acid receptor beta (RARbeta) gene.
Genesis (New York, N.Y. : 2000) 2002;32(2):91-4.
2002: Benoit Chapellier; Manuel Mark; Jean-Marie Garnier; Marianne LeMeur; Pierre Chambon; Norbert B Ghyselinck
A conditional floxed (loxP-flanked) allele for the retinoic acid receptor alpha (RARalpha) gene.
Genesis (New York, N.Y. : 2000) 2002;32(2):87-90.
2002: Alexander Crocoll; Ute Herzer; Norbert B Ghyselinck; Pierre Chambon; Andrew C B Cato
Interdigital apoptosis and downregulation of BAG-1 expression in mouse autopods.
Mechanisms of development 2002;111(1-2):149-52.
2001: Bénédicte Mascrez; Manuel Mark; Wojciech Krezel; Valérie Dupé; Marianne LeMeur; Norbert B Ghyselinck; Pierre Chambon
Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXR alpha.
Development (Cambridge, England) 2001;128(11):2049-62.
2001: Olivia Wendling; Norbert B Ghyselinck; Pierre Chambon; Manuel Mark
Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning.
Development (Cambridge, England) 2001;128(11):2031-8.
2001: M Mori; Norbert B Ghyselinck; Pierre Chambon; Manuel Mark
Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes.
Investigative ophthalmology & visual science 2001;42(6):1312-8.
2001: Philippe Kastner; H J Lawrence; C Waltzinger; Norbert B Ghyselinck; Pierre Chambon; Susan Chan
Positive and negative regulation of granulopoiesis by endogenous RARalpha.
Blood 2001;97(5):1314-20.
2000: Richard Mollard; Norbert B Ghyselinck; Olivia Wendling; Pierre Chambon; Manuel Mark
Stage-dependent responses of the developing lung to retinoic acid signaling.
The International journal of developmental biology 2000;44(5):457-62.
2000: Raymond Romand; Vincent Sapin; Norbert B Ghyselinck; Paul Avan; S Le Calvez; Pascal Dollé; Pierre Chambon; M Mark
Spatio-temporal distribution of cellular retinoid binding protein gene transcripts in the developing and the adult cochlea. Morphological and functional consequences in CRABP- and CRBPI-null mutant mice.
The European journal of neuroscience 2000;12(8):2793-804.
1999: Valérie Dupé; Norbert B Ghyselinck; Olivia Wendling; Pierre Chambon; Manuel Mark
Key roles of retinoic acid receptors alpha and beta in the patterning of the caudal hindbrain, pharyngeal arches and otocyst in the mouse.
Development (Cambridge, England) 1999;126(22):5051-9.
1999: Norbert B Ghyselinck; Claes O Båvik; Vincent Sapin; Manuel Mark; D Bonnier; Colette Hindelang; Andrée Dierich; Charlotte B Nilsson; Helen Håkansson; Patrick Sauvant; Véronique Azaïs-Braesco; M Frasson; Serge Picaud; Pierre Chambon
Cellular retinol-binding protein I is essential for vitamin A homeostasis.
The EMBO journal 1999;18(18):4903-14.
1999: Manuel Mark; Norbert B Ghyselinck; Olivia Wendling; Valérie Dupé; Bénédicte Mascrez; Philippe Kastner; Pierre Chambon
A genetic dissection of the retinoid signalling pathway in the mouse.
The Proceedings of the Nutrition Society 1999;58(3):609-13.
1999: Valérie Dupé; Norbert B Ghyselinck; Vilmos A Thomazy; Laszlo Nagy; Peter Davies; Pierre Chambon; Manuel Mark
Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods.
Developmental biology 1999;208(1):30-43.
1998: Bénédicte Mascrez; Manuel Mark; Andrée Dierich; Norbert B Ghyselinck; Philippe Kastner; Pierre Chambon
The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development.
Development (Cambridge, England) 1998;125(23):4691-707.
1998: M P Gaub; Yves Lutz; Norbert B Ghyselinck; I Scheuer; V Pfister; Pierre Chambon; Cécile Rochette-Egly
Nuclear detection of cellular retinoic acid binding proteins I and II with new antibodies.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(10):1103-11.
1998: Norbert B Ghyselinck; Olivia Wendling; Nadia Messaddeq; Andrée Dierich; C Lampron; D Décimo; Stéphane Viville; Pierre Chambon; Manuel Mark
Contribution of retinoic acid receptor beta isoforms to the formation of the conotruncal septum of the embryonic heart.
Developmental biology 1998;198(2):303-18.
1998: Wojciech Krezel; Norbert B Ghyselinck; Tarek A Samad; Valérie Dupé; Philippe Kastner; Emiliana Borrelli; Pierre Chambon
Impaired locomotion and dopamine signaling in retinoid receptor mutant mice.
Science (New York, N.Y.) 1998;279(5352):863-7.
1998: Manuel Mark; Norbert B Ghyselinck; Philippe Kastner; Valérie Dupé; Olivia Wendling; Wojciech Krezel; Bénédicte Mascrez; Pierre Chambon
Mesectoderm is a major target of retinoic acid action.
European journal of oral sciences 1998;106 Suppl 1():24-31.
1997: Philippe Kastner; Nadia Messaddeq; Manuel Mark; Olivia Wendling; J M Grondona; S Ward; Norbert B Ghyselinck; Pierre Chambon
Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes.
Development (Cambridge, England) 1997;124(23):4749-58.
1997: Norbert B Ghyselinck; Valérie Dupé; Andrée Dierich; Nadia Messaddeq; Jean-Marie Garnier; Cécile Rochette-Egly; Pierre Chambon; Manuel Mark
Role of the retinoic acid receptor beta (RARbeta) during mouse development.
The International journal of developmental biology 1997;41(3):425-47.
1997: Manuel Mark; Philippe Kastner; Norbert B Ghyselinck; Wojciech Krezel; Valérie Dupé; Pierre Chambon
[Genetic control of the development by retinoic acid].
Comptes rendus des séances de la Société de biologie et de ses filiales 1997;191(1):77-90.
1997: Philippe Kastner; Manuel Mark; Norbert B Ghyselinck; Wojciech Krezel; Valérie Dupé; J M Grondona; Pierre Chambon
Genetic evidence that the retinoid signal is transduced by heterodimeric RXR/RAR functional units during mouse development.
Development (Cambridge, England) 1997;124(2):313-26.
1992: D Lohnes; Andrée Dierich; Norbert B Ghyselinck; Philippe Kastner; C Lampron; Marianne LeMeur; Thomas Lufkin; C Mendelsohn; Harikrishna Nakshatri; Pierre Chambon
Retinoid receptors and binding proteins.
Journal of cell science. Supplement 1992;16():69-76.