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Adria Giacca

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Melanie Dawn Guenette; Margaret Hahn; Loretta Lam; Tamara Arenovich; Araba Chintoh; Adria Giacca; Celine Teo; Gary Remington
Atypical antipsychotics and effects of adrenergic and serotonergic receptor binding on insulin secretion in-vivo: an animal model.
Sandra Pereira; Michael C Riddell; Yaniv Shpilberg; Wen Qin Yu; Jacqueline L Beaudry; Cristina Dirlea; I George Fantus; María E Frigolet; B L Grégoire Nyomba; Edward Park; Adria Giacca
Duration of rise in free fatty acids determines salicylate's effect on hepatic insulin sensitivity.
Christine Tang; Frederick Yoon; Edith Arany; Astrid Chamson-Reig; Paresh Dandona; Marc Y Donath; Jan A Ehses; Husam Ghanim; Tracy T Goh; Khajag Koulajian; Gary F Lewis; Anthony E Naassan; Andrei I Oprescu; Adria Giacca
Susceptibility to fatty acid-induced β-cell dysfunction is enhanced in prediabetic diabetes-prone biobreeding rats: a potential link between β-cell lipotoxicity and islet inflammation.

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All Publications

2013: Melanie Dawn Guenette; Margaret Hahn; Loretta Lam; Tamara Arenovich; Araba Chintoh; Adria Giacca; Celine Teo; Gary Remington
Atypical antipsychotics and effects of adrenergic and serotonergic receptor binding on insulin secretion in-vivo: an animal model.
Schizophrenia research 2013;146(1-3):162-9.
2013: Sandra Pereira; Michael C Riddell; Yaniv Shpilberg; Wen Qin Yu; Jacqueline L Beaudry; Cristina Dirlea; I George Fantus; María E Frigolet; B L Grégoire Nyomba; Edward Park; Adria Giacca
Duration of rise in free fatty acids determines salicylate's effect on hepatic insulin sensitivity.
The Journal of endocrinology 2013;217(1):31-43.
2013: Christine Tang; Frederick Yoon; Edith Arany; Astrid Chamson-Reig; Paresh Dandona; Marc Y Donath; Jan A Ehses; Husam Ghanim; Tracy T Goh; Khajag Koulajian; Gary F Lewis; Anthony E Naassan; Andrei I Oprescu; Adria Giacca
Susceptibility to fatty acid-induced β-cell dysfunction is enhanced in prediabetic diabetes-prone biobreeding rats: a potential link between β-cell lipotoxicity and islet inflammation.
Endocrinology 2013;154(1):89-101.
2012: Michael K L Chu; Adria Giacca; Claudia R Gordijo; Alexander Ivovic; Khajag Koulajian; Jian Chen; Simon Chiang; Xiao Yu Wu; Yu Sun
In vitro and in vivo testing of glucose-responsive insulin-delivery microdevices in diabetic rats.
Lab on a chip 2012;12(14):2533-9.
2012: Danna M Breen; Paresh Dandona; Vernon W Dolinsky; Jason R B Dyck; Husam Ghanim; June Guo; Scott P Heximer; Margaret Mroziewicz; Evangelia L Tsiani; Hangjun Zhang; Michelle P Bendeck; Adria Giacca
Resveratrol inhibits neointimal formation after arterial injury through an endothelial nitric oxide synthase-dependent mechanism.
Atherosclerosis 2012;222(2):375-81.
2011: Margaret Hahn; Loretta Lam; Steve Mann; Tamara Arenovich; Araba Chintoh; Tony Cohn; Paul Fletcher; Adria Giacca; Melanie Guenette; Tom Wolever; Li Xu; Gary Remington
Atypical antipsychotics and effects of muscarinic, serotonergic, dopaminergic and histaminergic receptor binding on insulin secretion in vivo: an animal model.
Schizophrenia research 2011;131(1-3):90-5.
2011: Danna M Breen; Adria Giacca
Effects of insulin on the vasculature.
Current vascular pharmacology 2011;9(3):321-32.
2011: Adria Giacca; Changting Xiao; Andrei I Oprescu; Andre C Carpentier; Gary F Lewis
Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies.
American journal of physiology. Endocrinology and metabolism 2011;300(2):E255-62.
2010: Michael A Király; Jon Campbell; Edward Park; Holly E Bates; Jessica T Y Yue; Venket Rao; Stephen G Matthews; George Bikopoulos; Maria Rozakis-Adcock; Adria Giacca; Mladen Vranic; Michael C Riddell
Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats.
American journal of physiology. Endocrinology and metabolism 2010;298(3):E671-82.
2010: Danna M Breen; Jiwanjeet K Dhaliwall; Kalam K Chan; June Guo; Loretta Lam; Michelle P Bendeck; Adria Giacca
Insulin inhibits and oral sucrose increases neointimal growth after arterial injury in rats.
Journal of vascular research 2010;47(5):412-22.
2009: Jian Chen; Michael Chu; Khajag Koulajian; Xiao Yu Wu; Adria Giacca; Yu Sun
A monolithic polymeric microdevice for pH-responsive drug delivery.
Biomedical microdevices 2009;11(6):1251-7.
2009: Danna M Breen; Kalam K Chan; Jiwanjeet K Dhaliwall; Michael R Ward; Nael Al Koudsi; Loretta Lam; Melissa De Souza; Husam Ghanim; Paresh Dandona; Duncan J Stewart; Michelle P Bendeck; Adria Giacca
Insulin increases reendothelialization and inhibits cell migration and neointimal growth after arterial injury.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(7):1060-6.
2009: Araba F Chintoh; Steve W Mann; Loretta Lam; Adria Giacca; Paul Fletcher; Jose Nobrega; Gary Remington
Insulin resistance and secretion in vivo: effects of different antipsychotics in an animal model.
Schizophrenia research 2009;108(1-3):127-33.
2009: Hélène Duez; Angela C Smith; Changting Xiao; Adria Giacca; Linda Szeto; Daniel J Drucker; Gary F Lewis
Acute dipeptidyl peptidase-4 inhibition rapidly enhances insulin-mediated suppression of endogenous glucose production in mice.
Endocrinology 2009;150(1):56-62.
2008: Araba F Chintoh; Steve W Mann; Loretta Lam; Carol Lam; Tony A Cohn; Paul Fletcher; Jose N Nobrega; Adria Giacca; Gary Remington
Insulin resistance and decreased glucose-stimulated insulin secretion after acute olanzapine administration.
Journal of clinical psychopharmacology 2008;28(5):494-9.
2008: Araba F Chintoh; Steve W Mann; Tony K T Lam; Adria Giacca; Gary Remington
Insulin resistance following continuous, chronic olanzapine treatment: an animal model.
Schizophrenia research 2008;104(1-3):23-30.
2008: Jingyu Diao; Emma M Allister; Vasilij Koshkin; Simon C Lee; Alpana Bhattacharjee; Christine Tang; Adria Giacca; Catherine B Chan; Michael B Wheeler
UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):12057-62.
2008: Ignatius M Y Szeto; Alfred Aziz; Paul J Das; Ameer Y Taha; Nobuhiko Okubo; Sandra Reza-Lopez; Adria Giacca; G Harvey Anderson
High multivitamin intake by Wistar rats during pregnancy results in increased food intake and components of the metabolic syndrome in male offspring.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(2):R575-82.
2008: C Xiao; Adria Giacca; Gary F Lewis
Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men.
Diabetologia 2008;51(1):139-46.
2007: Andrei I Oprescu; George Bikopoulos; Anthony Naassan; Emma M Allister; Christine Tang; Edward Park; Hiroshi Uchino; Gary F Lewis; I George Fantus; Maria Rozakis-Adcock; Michael B Wheeler; Adria Giacca
Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo.
Diabetes 2007;56(12):2927-37.
2007: Edward Park; Victor Wong; Xinyu Guan; Andrei I Oprescu; Adria Giacca
Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo.
The Journal of endocrinology 2007;195(2):323-31.
2007: Christine Tang; Ping Han; Andrei I Oprescu; Simon C Lee; Armen V Gyulkhandanyan; Gary N Y Chan; Michael B Wheeler; Adria Giacca
Evidence for a role of superoxide generation in glucose-induced beta-cell dysfunction in vivo.
Diabetes 2007;56(11):2722-31.
2007: Tracy Goh; Timothy M Mason; Neehar Gupta; Abby So; Tony K T Lam; Loretta Lam; Gary F Lewis; Andrea Mari; Adria Giacca
Lipid-induced beta-cell dysfunction in vivo in models of progressive beta-cell failure.
American journal of physiology. Endocrinology and metabolism 2007;292(2):E549-60.
2006: Neehar Gupta; Edward Park; Harmanjit Sandhu; Tracy Goh; Vaja Tchipashvili; Adria Giacca
Direct and indirect effects of insulin on hepatic glucose production in diabetic depancreatized dogs during euglycemia.
The Journal of endocrinology 2006;190(3):695-702.
2006: Shu Chen; Tony K T Lam; Edward Park; Elena Burdett; Penny Y T Wang; Stephanie R Wiesenthal; Loretta Lam; Vaja Tchipashvili; I George Fantus; Adria Giacca
Oleate-induced decrease in hepatocyte insulin binding is mediated by PKC-delta.
Biochemical and biophysical research communications 2006;346(3):931-7.
2006: C Xiao; Adria Giacca; André Carpentier; Gary F Lewis
Differential effects of monounsaturated, polyunsaturated and saturated fat ingestion on glucose-stimulated insulin secretion, sensitivity and clearance in overweight and obese, non-diabetic humans.
Diabetologia 2006;49(6):1371-9.
2006: Hidenori Yoshii; Tony K T Lam; Neehar Gupta; Tracy Goh; C Andrew Haber; Hiroshi Uchino; Tony T Y Kim; Victor Z Chong; Keyur Shah; I George Fantus; Andrea Mari; Ryuzo Kawamori; Adria Giacca
Effects of portal free fatty acid elevation on insulin clearance and hepatic glucose flux.
American journal of physiology. Endocrinology and metabolism 2006;290(6):E1089-97.
2006: Thien Tran; Dinaz Naigamwalla; Andrei I Oprescu; Loretta Lam; Gail McKeown-Eyssen; W Robert Bruce; Adria Giacca
Hyperinsulinemia, but not other factors associated with insulin resistance, acutely enhances colorectal epithelial proliferation in vivo.
Endocrinology 2006;147(4):1830-7.
2005: Tony Kim; Kalam K Chan; Jiwanjeet K Dhaliwall; Nghia Huynh; Renee Suen; Hiroshi Uchino; Dinaz Naigamwalla; Michelle P Bendeck; Adria Giacca
Anti-atherogenic effect of insulin in vivo.
Journal of vascular research 2005;42(6):455-62.
2005: W Robert Bruce; Maria Cirocco; Adria Giacca; Y-I Kim; Norman E Marcon; Salomon Minkin
A pilot randomised controlled trial to reduce colorectal cancer risk markers associated with B-vitamin deficiency, insulin resistance and colonic inflammation.
British journal of cancer 2005;93(6):639-46.
2005: Hiroshi Uchino; Tony Kim; Tony K T Lam; Hidenori Yoshii; Peter Klement; Wendy Williams; Ryuzo Kawamori; Adria Giacca
FK-614, a selective peroxisome proliferator-activated receptor gamma agonist, improves peripheral glucose utilization while decreasing hepatic insulin extraction in alloxan-induced diabetic dogs.
Metabolism: clinical and experimental 2005;54(9):1250-8.
2005: Alfred Aziz; G Harvey Anderson; Adria Giacca; France Cho
Hyperglycemia after protein ingestion concurrent with injection of a GLP-1 receptor agonist in rats: a possible role for dietary peptides.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;289(3):R688-94.
2005: Ying Lin; Anders H Berg; Puneeth Iyengar; Tony K T Lam; Adria Giacca; Terry P Combs; Michael W Rajala; Xue-Liang Du; Brent Rollman; Weijie Li; Meredith Hawkins; Nir Barzilai; Christopher J Rhodes; I George Fantus; Michael Brownlee; Philipp E Scherer
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.
The Journal of biological chemistry 2005;280(6):4617-26.
2005: Nadeeja Wijesekara; Daniel Konrad; Mohamed Eweida; Craig Jefferies; Nicole Liadis; Adria Giacca; Michael A Crackower; Akira Suzuki; Tak W Mak; C Ronald Kahn; Amira Klip; Minna Woo
Muscle-specific Pten deletion protects against insulin resistance and diabetes.
Molecular and cellular biology 2005;25(3):1135-45.
2004: Nathalie Leung; T Sakaue; André Carpentier; Kristine D Uffelman; Adria Giacca; Gary F Lewis
Prolonged increase of plasma non-esterified fatty acids fully abolishes the stimulatory effect of 24 hours of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men.
Diabetologia 2004;47(2):204-13.
2004: Xiaolin Wang; Hui Li; Domenica De Leo; Wanbei Guo; Vasilij Koshkin; I George Fantus; Adria Giacca; Catherine B Chan; Sandy D Der; Michael B Wheeler
Gene and protein kinase expression profiling of reactive oxygen species-associated lipotoxicity in the pancreatic beta-cell line MIN6.
Diabetes 2004;53(1):129-40.
2003: C Andrew Haber; Tony K T Lam; Zhiwen Yu; Neehar Gupta; Tracy Goh; Elena Bogdanovic; Adria Giacca; I George Fantus
N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: possible role of oxidative stress.
American journal of physiology. Endocrinology and metabolism 2003;285(4):E744-53.
2003: André Carpentier; Bernard Zinman; Nathalie Leung; Adria Giacca; Anthony J G Hanley; Stewart B Harris; Robert A Hegele; Gary F Lewis
Free fatty acid-mediated impairment of glucose-stimulated insulin secretion in nondiabetic Oji-Cree individuals from the Sandy Lake community of Ontario, Canada: a population at very high risk for developing type 2 diabetes.
Diabetes 2003;52(6):1485-95.
2003: Tony K T Lam; André Carpentier; Gary F Lewis; GERALD VAN DE WERVE; I George Fantus; Adria Giacca
Mechanisms of the free fatty acid-induced increase in hepatic glucose production.
American journal of physiology. Endocrinology and metabolism 2003;284(5):E863-73.
2003: Chao-Hung Wang; Nathalie Leung; Nathalie Lapointe; Linda Szeto; Kristine D Uffelman; Adria Giacca; Jean-Lucien Rouleau; Gary F Lewis
Vasopeptidase inhibitor omapatrilat induces profound insulin sensitization and increases myocardial glucose uptake in Zucker fatty rats: Studies comparing a vasopeptidase inhibitor, angiotensin-converting enzyme inhibitor, and angiotensin II type I receptor blocker.
Circulation 2003;107(14):1923-9.
2003: Tony K T Lam; GERALD VAN DE WERVE; Adria Giacca
Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites.
American journal of physiology. Endocrinology and metabolism 2003;284(2):E281-90.
2003: Thien Tran; Neehar Gupta; Tracy Goh; Dinaz Naigamwalla; Marie Chia; Niloofar Koohestani; Shruti Mehrotra; Gail McKeown-Eyssen; Adria Giacca; W Robert Bruce
Direct measure of insulin sensitivity with the hyperinsulinemic-euglycemic clamp and surrogate measures of insulin sensitivity with the oral glucose tolerance test: correlations with aberrant crypt foci promotion in rats.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(1):47-56.
2002: Neehar Gupta; Harmanjit Sandhu; Tracy Goh; Keyur Shah; Stephanie R Wiesenthal; Hidenori Yoshii; Victor Chong; Tony K T Lam; C Andrew Haber; Wendy Williams; Vaja Tchipashvili; Adria Giacca
Insulin inhibits glucose production by a direct effect in diabetic depancreatized dogs during euglycemia.
American journal of physiology. Endocrinology and metabolism 2002;283(5):E1002-7.
2002: Tony K T Lam; Hidenori Yoshii; C Andrew Haber; Elena Bogdanovic; Loretta Lam; I George Fantus; Adria Giacca
Free fatty acid-induced hepatic insulin resistance: a potential role for protein kinase C-delta.
American journal of physiology. Endocrinology and metabolism 2002;283(4):E682-91.
2002: Robert L Dobbins; Lidia S Szczepaniak; Jeff Myhill; Yoshifumi Tamura; Hiroshi Uchino; Adria Giacca; J Denis McGarry
The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats.
Diabetes 2002;51(6):1825-33.
2002: Gary F Lewis; André Carpentier; Khosrow Adeli; Adria Giacca
Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes.
Endocrine reviews 2002;23(2):201-29.
2002: Timothy M Mason; B Chan; B El-Bahrani; Tracy Goh; Neehar Gupta; J Gamble; Z Qing Shi; Marc Prentki; George Steiner; Adria Giacca
The effect of chronic insulin delivery via the intraperitoneal versus the subcutaneous route on hepatic triglyceride secretion rate in streptozotocin diabetic rats.
Atherosclerosis 2002;161(2):345-52.
2002: W Robert Bruce; Adria Giacca; Alan Medline
Possible mechanisms relating diet to colorectal cancer risk.
IARC scientific publications 2002;156():277-81.
2001: André Carpentier; Adria Giacca; Gary F Lewis
Effect of increased plasma non-esterified fatty acids (NEFAs) on arginine-stimulated insulin secretion in obese humans.
Diabetologia 2001;44(11):1989-97.
2001: André Carpentier; Bruce W Patterson; Kristine D Uffelman; Adria Giacca; Mladen Vranic; Mark S Cattral; Gary F Lewis
The effect of systemic versus portal insulin delivery in pancreas transplantation on insulin action and VLDL metabolism.
Diabetes 2001;50(6):1402-13.
2001: SJ Fisher; ZQ Shi; H Lavina A Lickley; Suad Efendic; Mladen Vranic; Adria Giacca
Low-dose IGF-I has no selective advantage over insulin in regulating glucose metabolism in hyperglycemic depancreatized dogs.
The Journal of endocrinology 2001;168(1):49-58.
2000: W Robert Bruce; Adria Giacca; Alan Medline
Possible mechanisms relating diet and risk of colon cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(12):1271-9.
2000: Timothy M Mason; Neehar Gupta; Tracy Goh; B El-Bahrani; J Zannis; GERALD VAN DE WERVE; Adria Giacca
Chronic intraperitoneal insulin delivery, as compared with subcutaneous delivery, improves hepatic glucose metabolism in streptozotocin diabetic rats.
Metabolism: clinical and experimental 2000;49(11):1411-6.
2000: C K Wan; Adria Giacca; M Matsuhisa; B El-Bahrani; Loretta Lam; CD Rodgers; ZQ Shi
Increased responses of glucagon and glucose production to hypoglycemia with intraperitoneal versus subcutaneous insulin treatment.
Metabolism: clinical and experimental 2000;49(8):984-9.
2000: M Niwa; S Rashid; Kathy Shum; Julian Mathoo; Owen Chan; Vaja Tchipashvili; Ryuzo Kawamori; Mladen Vranic; Adria Giacca
Effect of JTT-501 on net hepatic glucose balance and peripheral glucose uptake in alloxan-induced diabetic dogs.
Metabolism: clinical and experimental 2000;49(7):862-7.
2000: André Carpentier; S D Mittelman; R N Bergman; Adria Giacca; Gary F Lewis
Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes.
Diabetes 2000;49(3):399-408.
2000: W Robert Bruce; Thomas M S Wolever; Adria Giacca
Mechanisms linking diet and colorectal cancer: the possible role of insulin resistance.
Nutrition and cancer 2000;37(1):19-26.
1999: André Carpentier; S D Mittelman; B Lamarche; R N Bergman; Adria Giacca; Gary F Lewis
Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation.
The American journal of physiology 1999;276(6 Pt 1):E1055-66.
1999: Harmanjit Sandhu; Stephanie R Wiesenthal; Patrick E MacDonald; RH McCall; Vaja Tchipashvili; S Rashid; Malathy Satkunarajah; David M Irwin; ZQ Shi; Patricia L Brubaker; Michael B Wheeler; Mladen Vranic; Suad Efendic; Adria Giacca
Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs.
Diabetes 1999;48(5):1045-53.
1999: Stephanie R Wiesenthal; Harmanjit Sandhu; RH McCall; Vaja Tchipashvili; Hidenori Yoshii; Kenneth S Polonsky; ZQ Shi; Gary F Lewis; Andrea Mari; Adria Giacca
Free fatty acids impair hepatic insulin extraction in vivo.
Diabetes 1999;48(4):766-74.
1999: Gary F Lewis; André Carpentier; D Bilinski; Adria Giacca; Mladen Vranic
Counterregulatory response to hypoglycemia differs according to the insulin delivery route, but does not affect glucose production in normal humans.
The Journal of clinical endocrinology and metabolism 1999;84(3):1037-46.
1999: Gary F Lewis; André Carpentier; Mladen Vranic; Adria Giacca
Resistance to insulin's acute direct hepatic effect in suppressing steady-state glucose production in individuals with type 2 diabetes.
Diabetes 1999;48(3):570-6.
1999: Timothy M Mason; Tracy Goh; Vaja Tchipashvili; Harmanjit Sandhu; Neehar Gupta; Gary F Lewis; Adria Giacca
Prolonged elevation of plasma free fatty acids desensitizes the insulin secretory response to glucose in vivo in rats.
Diabetes 1999;48(3):524-30.
1999: Adria Giacca; RH McCall; B Chan; ZQ Shi
Increased dependence of glucose production on peripheral insulin in diabetic depancreatized dogs.
Metabolism: clinical and experimental 1999;48(2):153-60.
1998: Adria Giacca; Y Groenewoud; EY Tsui; P McClean; Bernard Zinman
Glucose production, utilization, and cycling in response to moderate exercise in obese subjects with type 2 diabetes and mild hyperglycemia.
Diabetes 1998;47(11):1763-70.
1998: Gary F Lewis; Mladen Vranic; Adria Giacca
Role of free fatty acids and glucagon in the peripheral effect of insulin on glucose production in humans.
The American journal of physiology 1998;275(1 Pt 1):E177-86.
1998: RH McCall; Stephanie R Wiesenthal; ZQ Shi; Kenneth S Polonsky; Adria Giacca
Insulin acutely suppresses glucose production by both peripheral and hepatic effects in normal dogs.
The American journal of physiology 1998;274(2 Pt 1):E346-56.
1997: SJ Fisher; Michael Lekas; ZQ Shi; D Bilinski; G Carvalho; Adria Giacca; Mladen Vranic
Insulin-independent acute restoration of euglycemia normalizes the impaired glucose clearance during exercise in diabetic dogs.
Diabetes 1997;46(11):1805-12.
1997: Gary F Lewis; Mladen Vranic; P Harley; Adria Giacca
Fatty acids mediate the acute extrahepatic effects of insulin on hepatic glucose production in humans.
Diabetes 1997;46(7):1111-9.
1997: Gary F Lewis; Mladen Vranic; Adria Giacca
Glucagon enhances the direct suppressive effect of insulin on hepatic glucose production in humans.
The American journal of physiology 1997;272(3 Pt 1):E371-8.
1997: Adria Giacca; SJ Fisher; RH McCall; ZQ Shi; Mladen Vranic
Direct and indirect effects of insulin in suppressing glucose production in depancreatized dogs: role of glucagon.
Endocrinology 1997;138(3):999-1007.
1997: M Matsuhisa; ZQ Shi; C Wan; Michael Lekas; CD Rodgers; Adria Giacca; R Kawamori; Mladen Vranic
The effect of pioglitazone on hepatic glucose uptake measured with indirect and direct methods in alloxan-induced diabetic dogs.
Diabetes 1997;46(2):224-31.
1996: SJ Fisher; ZQ Shi; H Lavina A Lickley; Suad Efendic; Mladen Vranic; Adria Giacca
A moderate decline in specific activity does not lead to an underestimation of hepatic glucose production during a glucose clamp.
Metabolism: clinical and experimental 1996;45(5):587-93.
1996: SJ Fisher; Michael Lekas; RH McCall; ZQ Shi; Adria Giacca; Mladen Vranic
Determinants of glucose turnover in the pathophysiology of diabetes: an in vivo analysis in diabetic dogs.
Diabetes & metabolism 1996;22(2):111-21.
1996: Gary F Lewis; Bernard Zinman; Y Groenewoud; Mladen Vranic; Adria Giacca
Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans.
Diabetes 1996;45(4):454-62.
1994: ZQ Shi; Adria Giacca; S Fisher; Hubert Vidal; GERALD VAN DE WERVE; Mladen Vranic
Importance of substrate changes in the decrease of hepatic glucose cycling during insulin infusion and declining glycemia in the depancreatized dog.
Diabetes 1994;43(11):1284-90.
1994: Adria Giacca; SJ Fisher; ZQ Shi; R Gupta; H Lavina A Lickley; A Skottner; G H Anderson; Suad Efendic; Mladen Vranic
Insulin-like growth factor-I and insulin have no differential effects on glucose production and utilization under conditions of hyperglycemia.
Endocrinology 1994;134(5):2251-8.
1993: ZQ Shi; Adria Giacca; K Yamatani; SJ Fisher; H Lavina A Lickley; Mladen Vranic
Effects of subbasal insulin infusion on resting and exercise-induced glucose turnover in depancreatized dogs.
The American journal of physiology 1993;264(3 Pt 1):E334-41.
1993: ZQ Shi; Adria Giacca; SJ Fisher; Michael Lekas; D Bilinski; M Van Delangeryt; H Lavina A Lickley; Mladen Vranic
Indirect effects of insulin in regulating glucose fluxes.
Advances in experimental medicine and biology 1993;334():151-68.
1992: Amira Klip; André Marette; D Dimitrakoudis; T Ramlal; Adria Giacca; ZQ Shi; Mladen Vranic
Effect of diabetes on glucoregulation. From glucose transporters to glucose metabolism in vivo.
Diabetes care 1992;15(11):1747-66.
1992: Adria Giacca; SJ Fisher; ZQ Shi; R Gupta; H Lavina A Lickley; Mladen Vranic
Importance of peripheral insulin levels for insulin-induced suppression of glucose production in depancreatized dogs.
The Journal of clinical investigation 1992;90(5):1769-77.
1992: K Yamatani; ZQ Shi; Adria Giacca; R Gupta; S Fisher; H Lavina A Lickley; Mladen Vranic
Role of FFA-glucose cycle in glucoregulation during exercise in total absence of insulin.
The American journal of physiology 1992;263(4 Pt 1):E646-53.
1990: Adria Giacca; R Gupta; Suad Efendic; K Hall; A Skottner; L Lickley; Mladen Vranic
Differential effects of IGF-I and insulin on glucoregulation and fat metabolism in depancreatized dogs.
Diabetes 1990;39(3):340-7.