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Giuseppe Giaccone

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Antineoplastic Combined Chemotherapy Protocols

Chemicals & Drugs

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Publications

TOP 3
Nogová Lucia; Boellaard Ronald; Kobe Carsten; Hoetjes Nikie; Zander Thomas; Gross Stefan Hubert; Dimitrijevic Sasa; Pellas Theodore; Eschner Wolfgang; Schmidt Katja; Bangard Christopher; Hayes Wendy; Thomas Roman K; Dietlein Markus; Giaccone Giuseppe; Hoekstra Otto S; Lammertsma Adriaan A; Wolf Jürgen
Downregulation of 18F-FDG uptake in PET as an early pharmacodynamic effect in treatment of non-small cell lung cancer with the mTOR inhibitor everolimus.
Soria J-C; Shepherd F A; Douillard J-Y; Wolf J; Giaccone G; Crino L; Cappuzzo F; Sharma S; Gross S H; Dimitrijevic S; Di Scala L; Gardner H; Nogova L; Papadimitrakopoulou V
Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors.
Giaccone Giuseppe; Rajan Arun
Met amplification and HSP90 inhibitors.

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All Publications

2009: Nogová Lucia; Boellaard Ronald; Kobe Carsten; Hoetjes Nikie; Zander Thomas; Gross Stefan Hubert; Dimitrijevic Sasa; Pellas Theodore; Eschner Wolfgang; Schmidt Katja; Bangard Christopher; Hayes Wendy; Thomas Roman K; Dietlein Markus; Giaccone Giuseppe; Hoekstra Otto S; Lammertsma Adriaan A; Wolf Jürgen
Downregulation of 18F-FDG uptake in PET as an early pharmacodynamic effect in treatment of non-small cell lung cancer with the mTOR inhibitor everolimus.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(11):1815-9.
2009: Soria J-C; Shepherd F A; Douillard J-Y; Wolf J; Giaccone G; Crino L; Cappuzzo F; Sharma S; Gross S H; Dimitrijevic S; Di Scala L; Gardner H; Nogova L; Papadimitrakopoulou V
Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(10):1674-81.
2009: Giaccone Giuseppe; Rajan Arun
Met amplification and HSP90 inhibitors.
Cell cycle (Georgetown, Tex.) 2009;8(17):2682.
2009: Giaccone Giuseppe; Zatloukal Petr; Roubec Jaromir; Floor Karijn; Musil Jaromir; Kuta Milan; van Klaveren Rob J; Chaudhary Subhash; Gunther Adrie; Shamsili Setareh
Multicenter phase II trial of YM155, a small-molecule suppressor of survivin, in patients with advanced, refractory, non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(27):4481-6.
2009: van Riel J M; Peters G J; Mammatas L H; Honeywell R J; Laan A C; Ruyter R; van den Berg F G; Giaccone G; van Groeningen C J
A phase I and pharmacokinetic study of gemcitabine given by 24-h hepatic arterial infusion.
European journal of cancer (Oxford, England : 1990) 2009;45(14):2519-27.
2009: Jackman David M; Miller Vincent A; Cioffredi Leigh-Anne; Yeap Beow Y; Jänne Pasi A; Riely Gregory J; Ruiz Marielle Gallegos; Giaccone Giuseppe; Sequist Lecia V; Johnson Bruce E
Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(16):5267-73.
2009: Gutierrez Martin E; Kummar Shivaani; Giaccone Giuseppe
Next generation oncology drug development: opportunities and challenges.
Nature reviews. Clinical oncology 2009;6(5):259-65.
2009: Checinska Agnieszka; Giaccone Giuseppe; Rodriguez Jose A; Kruyt Frank A E; Jimenez Connie R
Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells.
Journal of proteomics 2009;72(4):575-85.
2009: Kummar Shivaani; Doroshow James H; Tomaszewski Joseph E; Calvert A Hilary; Lobbezoo Marinus; Giaccone Giuseppe;
Phase 0 clinical trials: recommendations from the Task Force on Methodology for the Development of Innovative Cancer Therapies.
European journal of cancer (Oxford, England : 1990) 2009;45(5):741-6.
2009: Giaccone Giuseppe; Iacona Renee B; Fandi Abderrahim; Janas Mette; Ochs Judith S; Herbst Roy S; Johnson David H
Epidermal growth factor receptor expression analysis in chemotherapy-naive patients with advanced non-small-cell lung cancer treated with gefitinib or placebo in combination with platinum-based chemotherapy.
Journal of cancer research and clinical oncology 2009;135(3):467-76.
2009: Roepman Paul; Jassem Jacek; Smit Egbert F; Muley Thomas; Niklinski Jacek; van de Velde Tony; Witteveen Anke T; Rzyman Witold; Floore Arno; Burgers Sjaak; Giaccone Giuseppe; Meister Michael; Dienemann Hendrik; Skrzypski Marcin; Kozlowski Miroslaw; Mooi Wolter J; van Zandwijk Nico
An immune response enriched 72-gene prognostic profile for early-stage non-small-cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(1):284-90.
2009: Galleges Ruiz M I; Floor K; Steinberg S M; Grünberg K; Thunnissen F B J M; Belien J A M; Meijer G A; Peters G J; Smit E F; Rodriguez J A; Giaccone G
Combined assessment of EGFR pathway-related molecular markers and prognosis of NSCLC patients.
British journal of cancer 2009;100(1):145-52.
2009: Carter Corey A; Rajan Arun; Giaccone Giuseppe
Plantar erythrodysesthesia with bullous otitis externa, toxicities from sorafenib: a case report.
Cases journal 2009;2():6264.
2009: Voortman Johannes; Pham Thang V; Knol Jaco C; Giaccone Giuseppe; Jimenez Connie R
Prediction of outcome of non-small cell lung cancer patients treated with chemotherapy and bortezomib by time-course MALDI-TOF-MS serum peptide profiling.
Proteome science 2009;7():34.
2009: van Cruijsen Hester; Ruiz Mariëlle Gallegos; van der Valk Paul; de Gruijl Tanja D; Giaccone Giuseppe
Tissue micro array analysis of ganglioside N-glycolyl GM3 expression and signal transducer and activator of transcription (STAT)-3 activation in relation to dendritic cell infiltration and microvessel density in non-small cell lung cancer.
BMC cancer 2009;9():180.
2008: Rajan Arun; Giaccone Giuseppe
Treatment of advanced thymoma and thymic carcinoma.
Current treatment options in oncology 2008;9(4-6):277-87.
2008: Lee Min-Jung; Kim Yeong Sang; Kummar Shivaani; Giaccone Giuseppe; Trepel Jane B
Histone deacetylase inhibitors in cancer therapy.
Current opinion in oncology 2008;20(6):639-49.
2008: Bottomley Andrew; Debruyne Channa; Felip Enriqueta; Millward Michael; Thiberville Luc; D'Addario Giannicola; Rome Lisa; Zatloukal Petr; Coens Corneel; Giaccone Giuseppe
Symptom and quality of life results of an international randomised phase III study of adjuvant vaccination with Bec2/BCG in responding patients with limited disease small-cell lung cancer.
European journal of cancer (Oxford, England : 1990) 2008;44(15):2178-84.
2008: Perk Lars R; Stigter-van Walsum Marijke; Visser Gerard W M; Kloet Reina W; Vosjan Maria J W D; Leemans C René; Giaccone Giuseppe; Albano Raffaella; Comoglio Paolo M; van Dongen Guus A M S
Quantitative PET imaging of Met-expressing human cancer xenografts with 89Zr-labelled monoclonal antibody DN30.
European journal of nuclear medicine and molecular imaging 2008;35(10):1857-67.
2008: van Cruijsen Hester; van der Veldt Astrid A M; Vroling Laura; Oosterhoff Dinja; Broxterman Henk J; Scheper Rik J; Giaccone Giuseppe; Haanen John B A G; van den Eertwegh Alfons J M; Boven Epie; Hoekman Klaas; de Gruijl Tanja D
Sunitinib-induced myeloid lineage redistribution in renal cell cancer patients: CD1c+ dendritic cell frequency predicts progression-free survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5884-92.
2008: Rajan A; Gutierrez M; Giaccone G
Newer opportunities in systemic therapy of lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19 Suppl 7():vii31-7.
2008: Bröker Linda E; Valdivieso Manual; Pilat Mary Jo; Deluca Pamela; Zhou Xiaofei; Parker Susan; Giaccone Giuseppe; Lorusso Patricia M
Effect of food on the pharmacokinetic behavior of the potent oral taxane BMS-275183.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(13):4186-91.
2008: Giaccone G; Zucali P A
Src as a potential therapeutic target in non-small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008;19(7):1219-23.
2008: Giovannetti Elisa; Lemos Clara; Tekle Christina; Smid Kees; Nannizzi Sara; Rodriguez José A; Ricciardi Simona; Danesi Romano; Giaccone Giuseppe; Peters Godefridus J
Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells.
Molecular pharmacology 2008;73(4):1290-300.
2008: Gutierrez Martin; Giaccone Giuseppe
Antiangiogenic therapy in nonsmall cell lung cancer.
Current opinion in oncology 2008;20(2):176-82.
2008: Barlési Fabrice; Giaccone Giuseppe; Gallegos-Ruiz Marielle I; Span Simone W; Lefesvre Pierre; Kruyt Frank A E; Rodriguez Jose Antonio
Genotype analysis of the VNTR polymorphism in the SMYD3 histone methyltransferase gene: lack of correlation with the level of histone H3 methylation in NSCLC tissues or with the risk of NSCLC.
International journal of cancer. Journal international du cancer 2008;122(6):1441-2.
2008: Eberhard David A; Giaccone Giuseppe; Johnson Bruce E;
Biomarkers of response to epidermal growth factor receptor inhibitors in Non-Small-Cell Lung Cancer Working Group: standardization for use in the clinical trial setting.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(6):983-94.
2008: Booth Christopher M; Calvert A Hilary; Giaccone Giuseppe; Lobbezoo Marinus W; Seymour Lesley K; Eisenhauer Elizabeth A
Endpoints and other considerations in phase I studies of targeted anticancer therapy: recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies (MDICT).
European journal of cancer (Oxford, England : 1990) 2008;44(1):19-24.
2008: Booth Christopher M; Calvert A Hilary; Giaccone Giuseppe; Lobbezoo Marinus W; Eisenhauer Elizabeth A; Seymour Lesley K
Design and conduct of phase II studies of targeted anticancer therapy: recommendations from the task force on methodology for the development of innovative cancer therapies (MDICT).
European journal of cancer (Oxford, England : 1990) 2008;44(1):25-9.
2008: Gallegos Ruiz Mariëlle I; Floor Karijn; Roepman Paul; Rodriguez José A; Meijer Gerrit A; Mooi Wolter J; Jassem Ewa; Niklinski Jacek; Muley Thomas; van Zandwijk Nico; Smit Egbert F; Beebe Kristin; Neckers Len; Ylstra Bauke; Giaccone Giuseppe
Integration of gene dosage and gene expression in non-small cell lung cancer, identification of HSP90 as potential target.
PloS one 2008;3(3):e0001722.
2007: Giaccone Giuseppe
18Fluorodeoxyglucose positron emission tomography, a standard diagnostic tool in lung cancer.
Journal of the National Cancer Institute 2007;99(23):1741-3.
2007: Gallegos Ruiz M I; Floor K; Vos W; Grünberg K; Meijer G A; Rodriguez J A; Giaccone G
Epidermal growth factor receptor (EGFR) gene copy number detection in non-small-cell lung cancer; a comparison of fluorescence in situ hybridization and chromogenic in situ hybridization.
Histopathology 2007;51(5):631-7.
2007: Engelsma Dieuwke; Rodriguez Jose A; Fish Alexander; Giaccone Giuseppe; Fornerod Maarten
Homodimerization antagonizes nuclear export of survivin.
Traffic (Copenhagen, Denmark) 2007;8(11):1495-502.
2007: Barlési Fabrice; Giaccone Giuseppe; Gallegos-Ruiz Marielle I; Loundou Anderson; Span Simone W; Lefesvre Pierre; Kruyt Frank A E; Rodriguez Jose Antonio
Global histone modifications predict prognosis of resected non small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(28):4358-64.
2007: Voortman Jens; Resende Tatiana P; Abou El Hassan Mohamed A I; Giaccone Giuseppe; Kruyt Frank A E
TRAIL therapy in non-small cell lung cancer cells: sensitization to death receptor-mediated apoptosis by proteasome inhibitor bortezomib.
Molecular cancer therapeutics 2007;6(7):2103-12.
2007: Bröker Linda E; Veltkamp Stephan A; Heath Elisabeth I; Kuenen Bart C; Gall Helen; Astier Ludovic; Parker Susan; Kayitalire Louis; Lorusso Patricia M; Schellens Jan H M; Giaccone Giuseppe
A phase I safety and pharmacologic study of a twice weekly dosing regimen of the oral taxane BMS-275183.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(13):3906-12.
2007: Meijerink Martijn R; van Cruijsen Hester; Hoekman Klaas; Kater Matthijs; van Schaik Cors; van Waesberghe Jan Hein T M; Giaccone Giuseppe; Manoliu Radu A
The use of perfusion CT for the evaluation of therapy combining AZD2171 with gefitinib in cancer patients.
European radiology 2007;17(7):1700-13.
2007: Giaccone Giuseppe
Advances at the Center for Cancer Research at the National Cancer Institute's Medical Oncology Branch.
Clinical advances in hematology & oncology : H&O 2007;5(6):443-4, 459.
2007: Voortman Jens; Smit Egbert F; Honeywell Richard; Kuenen Bart C; Peters Godefridus J; van de Velde Helgi; Giaccone Giuseppe
A parallel dose-escalation study of weekly and twice-weekly bortezomib in combination with gemcitabine and cisplatin in the first-line treatment of patients with advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(12):3642-51.
2007: Giaccone Giuseppe
The potential of antiangiogenic therapy in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(7):1961-70.
2007: Vischioni B; Oudejans J J; Kruyt F A E; Giaccone G; Rodriguez J A
Immunohistochemical detection of nuclear survivin in NSCLC: a comparison of commercial antibodies.
Histopathology 2007;50(5):671-5.
2007: Checinska Agnieszka; Hoogeland Bas S J; Rodriguez Jose A; Giaccone Giuseppe; Kruyt Frank A E
Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.
Experimental cell research 2007;313(6):1215-24.
2007: van Meerbeeck Jan P; Kramer Gijs W P M; Van Schil Paul E Y; Legrand Catherine; Smit Egbert F; Schramel Franz; Tjan-Heijnen Vivianne C; Biesma Bonne; Debruyne Channa; van Zandwijk Nico; Splinter Ted A W; Giaccone Giuseppe;
Randomized controlled trial of resection versus radiotherapy after induction chemotherapy in stage IIIA-N2 non-small-cell lung cancer.
Journal of the National Cancer Institute 2007;99(6):442-50.
2007: Voortman Jens; Checinska Agnieszka; Giaccone Giuseppe; Rodriguez Jose A; Kruyt Frank A E
Bortezomib, but not cisplatin, induces mitochondria-dependent apoptosis accompanied by up-regulation of noxa in the non-small cell lung cancer cell line NCI-H460.
Molecular cancer therapeutics 2007;6(3):1046-53.
2007: Honeywell R; Laan A C; van Groeningen C J; Strocchi E; Ruiter R; Giaccone G; Peters G J
The determination of gemcitabine and 2'-deoxycytidine in human plasma and tissue by APCI tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;847(2):142-52.
2007: Dumez Herlinde; Gall Helen; Capdeville Renaud; Dutreix Catherine; van Oosterom Allan T; Giaccone Giuseppe
A phase I and pharmacokinetic study of LAF389 administered to patients with advanced cancer.
Anti-cancer drugs 2007;18(2):219-25.
2007: Gallegos Ruiz Mariëlle I; van Cruijsen Hester; Smit Egbert F; Grünberg Katrien; Meijer Gerrit A; Rodriguez José A; Ylstra Bauke; Giaccone Giuseppe
Genetic heterogeneity in patients with multiple neoplastic lung lesions: a report of three cases.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2007;2(1):12-21.
2007: Belderbos José; Uitterhoeve Lon; van Zandwijk Nico; Belderbos Huub; Rodrigus Patrick; van de Vaart Paul; Price Allan; van Walree Nico; Legrand Catherine; Dussenne Sonia; Bartelink Harry; Giaccone Giuseppe; Koning Caro;
Randomised trial of sequential versus concurrent chemo-radiotherapy in patients with inoperable non-small cell lung cancer (EORTC 08972-22973).
European journal of cancer (Oxford, England : 1990) 2007;43(1):114-21.
2007: van Cruijsen H; Hoekman K; Stam A G M; van den Eertwegh A J M; Kuenen B C; Scheper R J; Giaccone G; de Gruijl T D
Defective differentiation of myeloid and plasmacytoid dendritic cells in advanced cancer patients is not normalized by tyrosine kinase inhibition of the vascular endothelial growth factor receptor.
Clinical & developmental immunology 2007;2007():17315.
2007: Voortman Jens; Checinska Agnieszka; Giaccone Giuseppe
The proteasomal and apoptotic phenotype determine bortezomib sensitivity of non-small cell lung cancer cells.
Molecular cancer 2007;6():73.
2007: Kesisis Georgios; Broxterman Henk; Giaccone Giuseppe
Angiogenesis inhibitors. Drug selectivity and target specificity.
Current pharmaceutical design 2007;13(27):2795-809.
2007: de Gunst Matheus M; Gallegos-Ruiz Marielle I; Giaccone Giuseppe; Rodriguez Jose Antonio
Functional analysis of cancer-associated EGFR mutants using a cellular assay with YFP-tagged EGFR intracellular domain.
Molecular cancer 2007;6():56.
2007: Gallegos Ruiz Mariëlle I; Floor Karijn; Rijmen Frank; Grünberg Katrien; Rodriguez José A; Giaccone Giuseppe
EGFR and K-ras mutation analysis in non-small cell lung cancer: comparison of paraffin embedded versus frozen specimens.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(3):257-64.
2006: Kris Mark G; Giaccone Giuseppe; Davies Angela; Fukuoka Masahiro; Garfield David H; Jassem Jacek; Quoix Elisabeth A; Sandler Alan B; Scagliotti Giorgio V; Van Meerbeeck Jan P; West Howard
Systemic therapy of bronchioloalveolar carcinoma: results of the first IASLC/ASCO consensus conference on bronchioloalveolar carcinoma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(9 Suppl):S32-6.
2006: Achille Michaela; Gallegos-Ruiz Marielle; Giaccone Giuseppe; Soria Jean-Charles
Response to erlotinib in first-line treatment of non-small-cell lung cancer in a white male smoker with squamous-cell histology.
Clinical lung cancer 2006;8(3):214-6.
2006: Vischioni Barbara; Oudejans Joost J; Vos Wim; Rodriguez Jose A; Giaccone Giuseppe
Frequent overexpression of aurora B kinase, a novel drug target, in non-small cell lung carcinoma patients.
Molecular cancer therapeutics 2006;5(11):2905-13.
2006: Zucali Paolo A; Giaccone Giuseppe
Biology and management of malignant pleural mesothelioma.
European journal of cancer (Oxford, England : 1990) 2006;42(16):2706-14.
2006: Efficace F; Bottomley A; Smit E F; Lianes P; Legrand C; Debruyne C; Schramel F; Smit H J; Gaafar R; Biesma B; Manegold C; Coens C; Giaccone G; Van Meerbeeck J;
Is a patient's self-reported health-related quality of life a prognostic factor for survival in non-small-cell lung cancer patients? A multivariate analysis of prognostic factors of EORTC study 08975.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(11):1698-704.
2006: Tijink Bernard M; Buter Jan; de Bree Remco; Giaccone Giuseppe; Lang Margreet S; Staab Alexander; Leemans C René; van Dongen Guus A M S
A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 1):6064-72.
2006: Giaccone Giuseppe; Gallegos Ruiz Marielle; Le Chevalier Thierry; Thatcher Nick; Smit Egbert; Rodriguez Jose Antonio; Janne Pasi; Oulid-Aissa Dalila; Soria Jean-Charles
Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(20 Pt 1):6049-55.
2006: Savonije J H; van Groeningen C J; van den Broek W J M; Rentinck M E M; Corstens F H M; Gundy C; Giaccone G; Marx J J M
Iron absorption during epoetin alfa therapy for chemotherapy-associated anaemia.
Cancer investigation 2006;24(6):562-6.
2006: Kroep J R; Smit E F; Giaccone G; Van der Born K; Beijnen J H; Van Groeningen C J; Van der Vijgh W J F; Postmus P E; Pinedo H M; Peters G J
Pharmacology of the paclitaxel-cisplatin, gemcitabine-cisplatin, and paclitaxel-gemcitabine combinations in patients with advanced non-small cell lung cancer.
Cancer chemotherapy and pharmacology 2006;58(4):509-16.
2006: Checinska Agnieszka; Oudejans Joost J; Span Simone W; Rodriguez Jose A; Kruyt Frank A E; Giaccone Giuseppe
The expression of TUCAN, an inhibitor of apoptosis protein, in patients with advanced non-small cell lung cancer treated with chemotherapy.
Anticancer research 2006;26(5B):3819-24.
2006: Giaccone Giuseppe; Wilmink Hanneke; Paul Marinus A; van der Valk Paul
Systemic treatment of malignant thymoma: a decade experience at a single institution.
American journal of clinical oncology 2006;29(4):336-44.
2006: Rodriguez J A; Lens S M A; Span S W; Vader G; Medema R H; Kruyt F A E; Giaccone G
Subcellular localization and nucleocytoplasmic transport of the chromosomal passenger proteins before nuclear envelope breakdown.
Oncogene 2006;25(35):4867-79.
2006: Kramer Gijsbert W P M; Legrand Catherine L; van Schil Paul; Uitterhoeve Lon; Smit Egbert F; Schramel Franz; Biesma Bonne; Tjan-Heijnen Vivianne; van Zandwijk Nico; Splinter Ted; Giaccone Giuseppe; van Meerbeeck Jan P;
Quality assurance of thoracic radiotherapy in EORTC 08941: a randomised trial of surgery versus thoracic radiotherapy in patients with stage IIIA non-small-cell lung cancer (NSCLC) after response to induction chemotherapy.
European journal of cancer (Oxford, England : 1990) 2006;42(10):1391-8.
2006: Lammertsma Adriaan A; Hoekstra Corneline J; Giaccone Giuseppe; Hoekstra Otto S
How should we analyse FDG PET studies for monitoring tumour response?
European journal of nuclear medicine and molecular imaging 2006;33 Suppl 1():16-21.
2006: Janmaat Maarten L; Gallegos-Ruiz Mariëlle I; Rodriguez José A; Meijer Gerrit A; Vervenne Walter L; Richel Dick J; Van Groeningen Cees; Giaccone Giuseppe
Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(10):1612-9.
2006: Lens Susanne M A; Rodriguez Jose A; Vader Gerben; Span Simone W; Giaccone Giuseppe; Medema René H
Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres.
Molecular biology of the cell 2006;17(4):1897-909.
2006: Bröker Linda E; de Vos Filip Y F L; van Groeningen Cees J; Kuenen Bart C; Gall Helen E; Woo Michael H; Voi Maurizio; Gietema Jourik A; de Vries Elisabeth G E; Giaccone Giuseppe
Phase I trial with BMS-275183, a novel oral taxane with promising antitumor activity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(6):1760-7.
2006: Rodriguez Jose Antonio; Giaccone Giuseppe
Keynote comment: are large-scale cancer-genomics projects ready to use?
The lancet oncology 2006;7(3):190-1.
2006: Bottomley Andrew; Gaafar Rabab; Manegold Christian; Burgers Sjaak; Coens Corneel; Legrand Catherine; Vincent Mark; Giaccone Giuseppe; Van Meerbeeck Jan;
Short-term treatment-related symptoms and quality of life: results from an international randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an EORTC Lung-Cancer Group and National Cancer Institute, Canada, Intergroup Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(9):1435-42.
2006: Savonije Jorine H; van Groeningen Cees J; Wormhoudt Lars W; Giaccone Guiseppe
Early intervention with epoetin alfa during platinum-based chemotherapy: an analysis of the results of a multicenter, randomized, controlled trial based on initial hemoglobin level.
The oncologist 2006;11(2):206-16.
2006: Savonije Jorine H; van Groeningen Cees J; Wormhoudt Lars W; Giaccone Guiseppe
Early Intervention with epoetin alfa during platinum-based chemotherapy: an analysis of quality-of-life results of a multicenter, randomized, controlled trial compared with population normative data.
The oncologist 2006;11(2):197-205.
2006: Vischioni Barbara; van der Valk Paul; Span Simone W; Kruyt Frank A E; Rodriguez Jose A; Giaccone Giuseppe
Expression and localization of inhibitor of apoptosis proteins in normal human tissues.
Human pathology 2006;37(1):78-86.
2006: Smorenburg C H; Peters G J; van Groeningen C J; Noordhuis P; Smid K; van Riel A M G H; Dercksen W; Pinedo H M; Giaccone G
Phase II study of tailored chemotherapy for advanced colorectal cancer with either 5-fluouracil and leucovorin or oxaliplatin and irinotecan based on the expression of thymidylate synthase and dihydropyrimidine dehydrogenase.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(1):35-42.
2006: Janmaat Maarten L; Rodriguez José A; Gallegos-Ruiz Mariëlle; Kruyt Frank A E; Giaccone Giuseppe
Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells.
International journal of cancer. Journal international du cancer 2006;118(1):209-14.
2006: Honeywell R; van Groeningen C J; Laan A C; Strocchi E; Ruiter R; Giaccone G; Peters G J
Analysis of deoxycytidine accumulation in gemcitabine treated patients.
Nucleosides, nucleotides & nucleic acids 2006;25(9-11):1225-32.
2006: Checinska Agnieszka; Giaccone Giuseppe; Hoogeland Bas S J; Ferreira Carlos G; Rodriguez Jose A; Kruyt Frank A E
TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells.
BMC cancer 2006;6():166.
2006: Voortman Jens; Giaccone Giuseppe
Severe reversible cardiac failure after bortezomib treatment combined with chemotherapy in a non-small cell lung cancer patient: a case report.
BMC cancer 2006;6():129.
2005: Giaccone Giuseppe
The role of EGFR-TK inhibition in non-small cell lung cancer.
Onkologie 2005;28(12):619-20.
2005: van Cruijsen Hester; Giaccone Giuseppe; Hoekman Klaas
Epidermal growth factor receptor and angiogenesis: Opportunities for combined anticancer strategies.
International journal of cancer. Journal international du cancer 2005;117(6):883-8.
2005: Buter Jan; Giaccone Giuseppe
EGFR inhibitors in lung cancer.
Oncology (Williston Park, N.Y.) 2005;19(13):1707-11; discussion 1711-2, 1720-3.
2005: Giaccone Giuseppe; Rodriguez Jose Antonio
EGFR inhibitors: what have we learned from the treatment of lung cancer?
Nature clinical practice. Oncology 2005;2(11):554-61.
2005: Bell Daphne W; Lynch Thomas J; Haserlat Sara M; Harris Patricia L; Okimoto Ross A; Brannigan Brian W; Sgroi Dennis C; Muir Beth; Riemenschneider Markus J; Iacona Renee Bailey; Krebs Annetta D; Johnson David H; Giaccone Giuseppe; Herbst Roy S; Manegold Christian; Fukuoka Masahiro; Kris Mark G; Baselga José; Ochs Judith S; Haber Daniel A
Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(31):8081-92.
2005: Ludwig Heinz; Khayat David; Giaccone Giuseppe; Facon Thierry
Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies.
Cancer 2005;104(9):1794-807.
2005: van Meerbeeck Jan P; Gaafar Rabab; Manegold Christian; Van Klaveren Rob J; Van Marck Eric A; Vincent Mark; Legrand Catherine; Bottomley Andrew; Debruyne Channa; Giaccone Giuseppe;
Randomized phase III study of cisplatin with or without raltitrexed in patients with malignant pleural mesothelioma: an intergroup study of the European Organisation for Research and Treatment of Cancer Lung Cancer Group and the National Cancer Institute of Canada.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(28):6881-9.
2005: Giaccone Giuseppe; Debruyne Channa; Felip Enriqueta; Chapman Paul B; Grant Stefan C; Millward Michael; Thiberville Luc; D'addario Giannicola; Coens Corneel; Rome Lisa S; Zatloukal Petr; Masso Oriol; Legrand Catherine
Phase III study of adjuvant vaccination with Bec2/bacille Calmette-Guerin in responding patients with limited-disease small-cell lung cancer (European Organisation for Research and Treatment of Cancer 08971-08971B; Silva Study).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(28):6854-64.
2005: Scagliotti Giorgio V; Smit Egbert; Bosquee Lionel; O'Brien Mary; Ardizzoni Andrea; Zatloukal Peter; Eberhardt Wilfried; Smid-Geirnaerdt Maartje; de Bruin Hein G; Dussenne Sonia; Legrand Catherine; Giaccone Giuseppe;
A phase II study of paclitaxel in advanced bronchioloalveolar carcinoma (EORTC trial 08956).
Lung cancer (Amsterdam, Netherlands) 2005;50(1):91-6.
2005: Hansma A H G; Broxterman H J; van der Horst I; Yuana Y; Boven E; Giaccone G; Pinedo H M; Hoekman K
Recombinant human endostatin administered as a 28-day continuous intravenous infusion, followed by daily subcutaneous injections: a phase I and pharmacokinetic study in patients with advanced cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(10):1695-701.
2005: Kuenen Bart C; Giaccone Giuseppe; Ruijter Rita; Kok Astrid; Schalkwijk Casper; Hoekman Klaas; Pinedo Herbert M
Dose-finding study of the multitargeted tyrosine kinase inhibitor SU6668 in patients with advanced malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(17):6240-6.
2005: Giaccone Giuseppe
Targeting HER1/EGFR in cancer therapy: experience with erlotinib.
Future oncology (London, England) 2005;1(4):449-60.
2005: Janmaat Maarten L; Rodriguez José A; Jimeno José; Kruyt Frank A E; Giaccone Giuseppe
Kahalalide F induces necrosis-like cell death that involves depletion of ErbB3 and inhibition of Akt signaling.
Molecular pharmacology 2005;68(2):502-10.
2005: Savonije J H; van Groeningen C J; van Bochove A; Honkoop A H; van Felius C L; Wormhoudt L W; Giaccone G
Effects of early intervention with epoetin alfa on transfusion requirement, hemoglobin level and survival during platinum-based chemotherapy: Results of a multicenter randomised controlled trial.
European journal of cancer (Oxford, England : 1990) 2005;41(11):1560-9.
2005: Uyl-de Groot Carin A; Giaccone Giuseppe
Health economics: can we afford an unrestricted use of new biological agents in gastrointestinal oncology?
Current opinion in oncology 2005;17(4):392-6.
2005: Giaccone Giuseppe
EGFR point mutation confers resistance to gefitinib in a patient with non-small-cell lung cancer.
Nature clinical practice. Oncology 2005;2(6):296-7.
2005: Giaccone Giuseppe
Epidermal growth factor receptor inhibitors in the treatment of non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(14):3235-42.
2005: Bröker Linda E; Kruyt Frank A E; Giaccone Giuseppe
Cell death independent of caspases: a review.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(9):3155-62.
2005: Boven E; Westerman M; van Groeningen C J; Verschraagen M; Ruijter R; Zegers I; van der Vijgh W J F; Giaccone G
Phase I and pharmacokinetic study of the novel chemoprotector BNP7787 in combination with cisplatin and attempt to eliminate the hydration schedule.
British journal of cancer 2005;92(9):1636-43.
2005: Ferrer Miriam; Rodríguez Jose A; Spierings Ellen A; de Winter Johan P; Giaccone Giuseppe; Kruyt Frank A E
Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export.
Human molecular genetics 2005;14(10):1271-81.
2005: Giaccone G
HER1/EGFR-targeted agents: predicting the future for patients with unpredictable outcomes to therapy.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16(4):538-48.
2005: Oosterhoff D; Overmeer R M; de Graaf M; van der Meulen I H; Giaccone G; van Beusechem V W; Haisma H J; Pinedo H M; Gerritsen W R
Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11.
British journal of cancer 2005;92(5):882-7.
2005: Giaccone Giuseppe
Treatment of malignant thymoma.
Current opinion in oncology 2005;17(2):140-6.
2005: Ferrer Miriam; Span Simone W; Vischioni Barbara; Oudejans Joost J; van Diest Paul J; de Winter Johan P; Giaccone Giuseppe; Kruyt Frank A E
FANCD2 expression in advanced non-small-cell lung cancer and response to platinum-based chemotherapy.
Clinical lung cancer 2005;6(4):250-4.
2005: Giaccone Giuseppe; Smit Egbert
Lung cancer.
Cancer chemotherapy and biological response modifiers 2005;22():413-42.
2005: Buter J; Giaccone G
Medical treatment of non-small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2005;16 Suppl 2():ii229-32.
2004: Roz Luca; Andriani Francesca; Ferreira Carlos G; Giaccone Giuseppe; Sozzi Gabriella
The apoptotic pathway triggered by the Fhit protein in lung cancer cell lines is not affected by Bcl-2 or Bcl-x(L) overexpression.
Oncogene 2004;23(56):9102-10.
2004: Vischioni B; van der Valk P; Span S W; Kruyt F A E; Rodriguez J A; Giaccone G
Nuclear localization of survivin is a positive prognostic factor for survival in advanced non-small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(11):1654-60.
2004: Geoerger Birgit; Vassal Gilles; Opolon Paule; Dirven Clemens M F; Morizet Jackie; Laudani Lysiane; Grill Jacques; Giaccone Giuseppe; Vandertop W Peter; Gerritsen Winald R; van Beusechem Victor W
Oncolytic activity of p53-expressing conditionally replicative adenovirus AdDelta24-p53 against human malignant glioma.
Cancer research 2004;64(16):5753-9.
2004: Vischioni Barbara; Giaccone Giuseppe; Span Simone W; Kruyt Frank A E; Rodriguez Jose A
Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2.
Experimental cell research 2004;298(2):535-48.
2004: Ferrer Miriam; de Winter Johan P; Mastenbroek D C Jeroen; Curiel David T; Gerritsen Winald R; Giaccone Giuseppe; Kruyt Frank A E
Chemosensitizing tumor cells by targeting the Fanconi anemia pathway with an adenovirus overexpressing dominant-negative FANCA.
Cancer gene therapy 2004;11(8):539-46.
2004: Croles N; Smorenburg C H; van Groeningen C J; Giaccone G; Boven E
FOLFOX3 in heavily pretreated patients with metastatic colorectal cancer.
The Netherlands journal of medicine 2004;62(7):242-5.
2004: van der Vliet Hans J J; Molling Johan W; von Blomberg B Mary E; Nishi Nobusuke; Kölgen Wendy; van den Eertwegh Alfons J M; Pinedo Herbert M; Giaccone Giuseppe; Scheper Rik J
The immunoregulatory role of CD1d-restricted natural killer T cells in disease.
Clinical immunology (Orlando, Fla.) 2004;112(1):8-23.
2004: Abou El Hassan M A I; Mastenbroek D C J; Gerritsen W R; Giaccone G; Kruyt F A E
Overexpression of Bcl2 abrogates chemo- and radiotherapy-induced sensitisation of NCI-H460 non-small-cell lung cancer cells to adenovirus-mediated expression of full-length TRAIL.
British journal of cancer 2004;91(1):171-7.
2004: Giaccone Giuseppe
The role of gefitinib in lung cancer treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 2):4233s-4237s.
2004: Lynch Thomas J; Adjei Alex A; Bunn Paul A; DuBois Raymond N; Gandara David R; Giaccone Giuseppe; Govindan Ramaswamy; Herbst Roy S; Johnson Bruce E; Khuri Fadlo R; Perez-Soler Roman; Rosell Rafael; Rowinsky Eric K; Sandler Alan B; Scagliotti Giorgio V; Schiller Joan H; Shapiro Geoffrey I; Socinski Mark A; Hart Carol S
Novel agents in the treatment of lung cancer: conference summary statement.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 2):4199s-4204s.
2004: Peters Godefridus J; Noordhuis Paul; Van Groeningen Cornelis J; Giaccone Giuseppe; Holwerda Ulbe; Voorn Daphne; Schrijvers Ad; Schornagel Jan H; Beijnen Jos H; Fumoleau Pierre; Schellens Jan H M
The effect of food on the pharmacokinetics of S-1 after single oral administration to patients with solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 1):4072-6.
2004: Giaccone G; González-Larriba J L; van Oosterom A T; Alfonso R; Smit E F; Martens M; Peters G J; van der Vijgh W J F; Smith R; Averbuch S; Fandi A
Combination therapy with gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, gemcitabine and cisplatin in patients with advanced solid tumors.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(5):831-8.
2004: Giaccone G; Smit E F; de Jonge M; Dansin E; Briasoulis E; Ardizzoni A; Douillard J-Y; Spaeth D; Lacombe D; Baron B; Bachmann P; Fumoleau P;
Glufosfamide administered by 1-hour infusion as a second-line treatment for advanced non-small cell lung cancer; a phase II trial of the EORTC-New Drug Development Group.
European journal of cancer (Oxford, England : 1990) 2004;40(5):667-72.
2004: De Lange S M; van Groeningen C J; Kroep J R; Van Bochove A; Snijders J F; Peters G J; Pinedo H M; Giaccone G
Phase II trial of cisplatin and gemcitabine in patients with advanced gastric cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(3):484-8.
2004: Herbst Roy S; Giaccone Giuseppe; Schiller Joan H; Natale Ronald B; Miller Vincent; Manegold Christian; Scagliotti Giorgio; Rosell Rafael; Oliff Ira; Reeves James A; Wolf Michael K; Krebs Annetta D; Averbuch Steven D; Ochs Judith S; Grous John; Fandi Abderrahim; Johnson David H
Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial--INTACT 2.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(5):785-94.
2004: Giaccone Giuseppe; Herbst Roy S; Manegold Christian; Scagliotti Giorgio; Rosell Rafael; Miller Vincent; Natale Ronald B; Schiller Joan H; Von Pawel Joachim; Pluzanska Anna; Gatzemeier Ulrich; Grous John; Ochs Judith S; Averbuch Steven D; Wolf Michael K; Rennie Pamela; Fandi Abderrahim; Johnson David H
Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial--INTACT 1.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(5):777-84.
2004: Kroep J R; Pinedo H M; Giaccone G; Van Bochove A; Peters G J; Van Groeningen C J
Phase II study of cisplatin preceding gemcitabine in patients with advanced oesophageal cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(2):230-5.
2004: Bröker Linda E; Huisman Cynthia; Span Simone W; Rodriguez José A; Kruyt Frank A E; Giaccone Giuseppe
Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells.
Cancer research 2004;64(1):27-30.
2004: van Klaveren Rob J; Aerts Joachim G J V; de Bruin Hein; Giaccone Guiseppe; Manegold Christian; van Meerbeeck Jan P
Inadequacy of the RECIST criteria for response evaluation in patients with malignant pleural mesothelioma.
Lung cancer (Amsterdam, Netherlands) 2004;43(1):63-9.
2004: van Riel J M G H; van Groeningen C J; de Greve J; Gruia G; Pinedo H M; Giaccone G
Continuous infusion of hepatic arterial irinotecan in pretreated patients with colorectal cancer metastatic to the liver.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(1):59-63.
2004: Giaccone G
Twenty-five years of treating advanced NSCLC: what have we achieved?
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15 Suppl 4():iv81-3.
2003: Smit Egbert F; van Meerbeeck Jan P A M; Lianes Pilar; Debruyne Channa; Legrand Catherine; Schramel Franz; Smit Hans; Gaafar Rabab; Biesma Bonne; Manegold Chris; Neymark Niels; Giaccone Giuseppe;
Three-arm randomized study of two cisplatin-based regimens and paclitaxel plus gemcitabine in advanced non-small-cell lung cancer: a phase III trial of the European Organization for Research and Treatment of Cancer Lung Cancer Group--EORTC 08975.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(21):3909-17.
2003: Kruyt Frank A E; Checinska Agnieszka; Giaccone Guiseppe; Ferreira Carlos G
Correspondence re: L. Yang et al., Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide. Cancer Res., 63: 831-837, 2003.
Cancer research 2003;63(19):6566-7; author reply 6568.
2003: Scagliotti Giorgio V; Fossati Roldano; Torri Valter; Crinò Lucio; Giaccone Giuseppe; Silvano Giovanni; Martelli Massimo; Clerici Maurizia; Cognetti Francesco; Tonato Maurizio;
Randomized study of adjuvant chemotherapy for completely resected stage I, II, or IIIA non-small-cell Lung cancer.
Journal of the National Cancer Institute 2003;95(19):1453-61.
2003: Bunn Paul A; Shepherd Frances A; Sandler Alan; Le Chevalier Thierry; Belani Chandra P; Kosmidis Paris A; Scagliotti Giorgio V; Giaccone Giuseppe
Ongoing and future trials of biologic therapies in lung cancer.
Lung cancer (Amsterdam, Netherlands) 2003;41 Suppl 1():S175-86.
2003: Hirsch Fred R; Bunn Paul A; Johnson David H; Giaccone Guiseppe; Rosell Rafael
Lung cancer. Introduction.
Lung cancer (Amsterdam, Netherlands) 2003;41 Suppl 1():S1.
2003: van der Vliet Hans J J; Molling Johan W; Nishi Nobusuke; Masterson Allan J; Kölgen Wendy; Porcelli Steven A; van den Eertwegh Alfons J M; von Blomberg B Mary E; Pinedo Herbert M; Giaccone Giuseppe; Scheper Rik J
Polarization of Valpha24+ Vbeta11+ natural killer T cells of healthy volunteers and cancer patients using alpha-galactosylceramide-loaded and environmentally instructed dendritic cells.
Cancer research 2003;63(14):4101-6.
2003: O'Brien M E R; Splinter T; Smit E F; Biesma B; Krzakowski M; Tjan-Heijnen V C G; Van Bochove A; Stigt J; Smid-Geirnaerdt M J A; Debruyne C; Legrand C; Giaccone G;
Carboplatin and paclitaxol (Taxol) as an induction regimen for patients with biopsy-proven stage IIIA N2 non-small cell lung cancer. an EORTC phase II study (EORTC 08958).
European journal of cancer (Oxford, England : 1990) 2003;39(10):1416-22.
2003: Peters G J; Noordhuis P; Van Kuilenburg A B P; Schornagel J H; Gall H; Turner S L; Swart M S; Voorn D; Van Gennip A H; Wanders J; Holwerda U; Smid K; Giaccone G; Fumoleau P; Van Groeningen C J
Pharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors.
Cancer chemotherapy and pharmacology 2003;52(1):1-12.
2003: Rodriguez Jose A; Span Simone W; Kruyt Frank A E; Giaccone Giuseppe
Subcellular localization of CrmA: identification of a novel leucine-rich nuclear export signal conserved in anti-apoptotic serpins.
The Biochemical journal 2003;373(Pt 1):251-9.
2003: Janmaat Maarten L; Kruyt Frank A E; Rodriguez José A; Giaccone Giuseppe
Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(6):2316-26.
2003: Dziadziuszko R; Ardizzoni A; Postmus P E; Smit E F; Price A; Debruyne C; Legrand C; Giaccone G;
Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases. a phase II study of the EORTC Lung Cancer Group (08965).
European journal of cancer (Oxford, England : 1990) 2003;39(9):1271-6.
2003: Ferrer Miriam; Izeboud Thijs; Ferreira Carlos G; Span Simone W; Giaccone Giuseppe; Kruyt Frank A E
Cisplatin triggers apoptotic or nonapoptotic cell death in Fanconi anemia lymphoblasts in a concentration-dependent manner.
Experimental cell research 2003;286(2):381-95.
2003: Fukuoka Masahiro; Yano Seiji; Giaccone Giuseppe; Tamura Tomohide; Nakagawa Kazuhiko; Douillard Jean-Yves; Nishiwaki Yutaka; Vansteenkiste Johan; Kudoh Shinzoh; Rischin Danny; Eek Richard; Horai Takeshi; Noda Kazumasa; Takata Ichiro; Smit Egbert; Averbuch Steven; Macleod Angela; Feyereislova Andrea; Dong Rui-Ping; Baselga José
Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(12):2237-46.
2003: Baas P; Ardizzoni A; Grossi F; Nackaerts K; Numico G; Van Marck E; van de Vijver M; Monetti F; Smid-Geirnaerdt M J A; van Zandwijk N; Debruyne C; Legrand C; Giaccone G;
The activity of raltitrexed (Tomudex) in malignant pleural mesothelioma: an EORTC phase II study (08992).
European journal of cancer (Oxford, England : 1990) 2003;39(3):353-7.
2003: Tjan-Heijnen V C G; Caleo S; Postmus P E; Ardizzoni A; Burghouts J T M; Buccholz E; Biesma B; Gorlia T; Crott R; Giaccone G; Debruyne C; Manegold C;
Economic evaluation of antibiotic prophylaxis in small-cell lung cancer patients receiving chemotherapy: an EORTC double-blind placebo-controlled phase III study (08923).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(2):248-57.
2003: Giaccone Giuseppe; Smit Egbert
Lung cancer.
Cancer chemotherapy and biological response modifiers 2003;21():445-83.
2003: Janmaat M L; Giaccone G
The epidermal growth factor receptor pathway and its inhibition as anticancer therapy.
Drugs of today (Barcelona, Spain : 1998) 2003;39 Suppl C():61-80.
2003: Janmaat Maarten L; Giaccone Giuseppe
Small-molecule epidermal growth factor receptor tyrosine kinase inhibitors.
The oncologist 2003;8(6):576-86.
2003: Lobbezoo Marinus W; Giaccone Giuseppe; Van Kalken Coenraad;
Signal transduction modulators for cancer therapy: from promise to practice?
The oncologist 2003;8(2):210-3.
2002: Giaccone Giuseppe; Punt Cornelis J A; Ando Yoshitaka; Ruijter Rita; Nishi Nobusuke; Peters Marlies; von Blomberg B Mary E; Scheper Rik J; van der Vliet Hans J J; van den Eertwegh Alfons J M; Roelvink Marja; Beijnen Jos; Zwierzina Heinz; Pinedo Herbert M
A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3702-9.
2002: Bröker Linda E; Giaccone Giuseppe
The role of new agents in the treatment of non-small cell lung cancer.
European journal of cancer (Oxford, England : 1990) 2002;38(18):2347-61.
2002: Shepherd Frances A; Giaccone Giuseppe; Seymour Lesley; Debruyne Channa; Bezjak Andrea; Hirsh Vera; Smylie Michael; Rubin Sheldon; Martins Heidi; Lamont Alan; Krzakowski Maciej; Sadura Anna; Zee Benny
Prospective, randomized, double-blind, placebo-controlled trial of marimastat after response to first-line chemotherapy in patients with small-cell lung cancer: a trial of the National Cancer Institute of Canada-Clinical Trials Group and the European Organization for Research and Treatment of Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(22):4434-9.
2002: Giaccone Giuseppe
Targeted therapy in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2002;38 Suppl 2():S29-32.
2002: Giaccone Giuseppe
Clinical impact of novel treatment strategies.
Oncogene 2002;21(45):6970-81.
2002: Ardizzoni Andrea; Tjan-Heijnen Vivianne C G; Postmus Pieter E; Buchholz Erica; Biesma Bonne; Karnicka-Mlodkowska Hanna; Dziadziuszko Rafal; Burghouts Jos; Van Meerbeeck Jan P; Gans Steven; Legrand Catherine; Debruyne Channa; Giaccone Giuseppe; Manegold Christian;
Standard versus intensified chemotherapy with granulocyte colony-stimulating factor support in small-cell lung cancer: a prospective European Organization for Research and Treatment of Cancer-Lung Cancer Group Phase III Trial-08923.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(19):3947-55.
2002: van der Vliet Hans J J; Pinedo Herbert M; von Blomberg B Mary E; van den Eertwegh Alfons J M; Scheper Rik J; Giaccone Giuseppe
Natural Killer T cells.
The lancet oncology 2002;3(9):574.
2002: Bröker Linda E; Huisman Cynthia; Ferreira Carlos G; Rodriguez José A; Kruyt Frank A E; Giaccone Giuseppe
Late activation of apoptotic pathways plays a negligible role in mediating the cytotoxic effects of discodermolide and epothilone B in non-small cell lung cancer cells.
Cancer research 2002;62(14):4081-8.
2002: Ferreira Carlos G; Epping Mirjam; Kruyt Frank A E; Giaccone Giuseppe
Apoptosis: target of cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2024-34.
2002: Giaccone Giuseppe;
Early results of a randomized phase III trial of platinum-containing doublets versus a nonplatinum doublet in the treatment of advanced non-small cell lung cancer: European Organization for Research and Treatment of Cancer 08975.
Seminars in oncology 2002;29(3 Suppl 9):47-9.
2002: de Lange S M; van Groeningen C J; Meijer O W M; Cuesta M A; Langendijk J A; van Riel J M G H; Pinedo H M; Peters G J; Meijer S; Slotman B J; Giaccone G
Gemcitabine-radiotherapy in patients with locally advanced pancreatic cancer.
European journal of cancer (Oxford, England : 1990) 2002;38(9):1212-7.
2002: Baars A; Claessen A M E; Wagstaff J; Giaccone G; Scheper R J; Meijer S; Schakel M J A G; Gall H E; Meijer C J L M; Vermorken J B; Pinedo H M; van den Eertwegh A J M
A phase II study of active specific immunotherapy and 5-FU/Leucovorin as adjuvant therapy for stage III colon carcinoma.
British journal of cancer 2002;86(8):1230-4.
2002: van Meerbeeck J P; Baas P; Debruyne C; Smit E F; van Klaveren R J; Galdermans D; Lentz M A; Manegold C; Giaccone G;
A phase II EORTC study of temozolomide in patients with malignant pleural mesothelioma.
European journal of cancer (Oxford, England : 1990) 2002;38(6):779-83.
2002: Rodríguez Jose A; Span Simone W; Ferreira Carlos G M; Kruyt Frank A E; Giaccone Giuseppe
CRM1-mediated nuclear export determines the cytoplasmic localization of the antiapoptotic protein Survivin.
Experimental cell research 2002;275(1):44-53.
2002: Crul Mirjam; Mathôt Ron A; Giaccone Giuseppe; Punt Cornelis A; Rosing Hilde; Hillebrand Michel X; Ando Yoshitaka; Nishi Nobosuke; Tanaka Hideji; Schellens Jan M; Beijnen Jos H
Population pharmacokinetics of the novel anticancer agent KRN7000.
Cancer chemotherapy and pharmacology 2002;49(4):287-93.
2002: Kuenen Bart C; Rosen Lee; Smit Egbert F; Parson Mandy R N; Levi Marcel; Ruijter Rita; Huisman Holger; Kedde Marc A; Noordhuis Paul; van der Vijgh Wim J F; Peters Godefridus J; Cropp Gillian F; Scigalla Paul; Hoekman Klaus; Pinedo Herbert M; Giaccone Giuseppe
Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(6):1657-67.
2002: Huisman Cynthia; Ferreira Carlos G; Bröker Linda E; Rodriguez Jose A; Smit Egbert F; Postmus Pieter E; Kruyt Frank A E; Giaccone Giuseppe
Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):596-606.
2002: van Riel Johanna M G H; van Groeningen Cees J; Kedde Mark A; Gall Helen; Leisink Johanna M A; Gruia Gabriella; Pinedo Herbert M; van der Vijgh Wim J F; Giaccone Giuseppe
Continuous administration of irinotecan by hepatic arterial infusion: a phase I and pharmacokinetic study.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):405-12.
2002: van der Vliet Hans J J; von Blomberg B Mary E; Hazenberg Mette D; Nishi Nobusuke; Otto Sigrid A; van Benthem Birgit H; Prins Maria; Claessen Frans A; van den Eertwegh Alfons J M; Giaccone Giuseppe; Miedema Frank; Scheper Rik J; Pinedo Herbert M
Selective decrease in circulating V alpha 24+V beta 11+ NKT cells during HIV type 1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1490-5.
2002: Ferreira Carlos G; Huisman Cynthia; Giaccone Giuseppe
Novel approaches to the treatment of non-small cell lung cancer.
Critical reviews in oncology/hematology 2002;41(1):57-77.
2002: Giaccone Giuseppe; Smit Egbert F
Update on the systemic treatment of lung cancer.
Cancer chemotherapy and biological response modifiers 2002;20():697-716.
2002: Cerny T; Giaccone G
Pleura mesothelioma: combined modality treatments.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2002;13 Suppl 4():217-25.
2001: Hadithi M; van Boxem T J; Giaccone G; Postmus P E
Exercise-induced spontaneous hemothorax insinuates trauma; yet unmasks a lament disorder.
The Netherlands journal of medicine 2001;59(6):292-4.
2001: Huisman C; Postmus P E; Giaccone G; Smit E F
A phase I study of sequential intravenous topotecan and etoposide in lung cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2001;12(11):1567-73.
2001: Huisman C; Biesma B; Postmus P E; Giaccone G; Schramel F M; Smit E F
Accelerated cisplatin and high-dose epirubicin with G-CSF support in patients with relapsed non-small-cell lung cancer: feasibility and efficacy.
British journal of cancer 2001;85(10):1456-61.
2001: Giaccone G
State of the art in systemic treatment of lung cancer.
European journal of cancer (Oxford, England : 1990) 2001;37 Suppl 7():S99-114.
2001: Tjan-Heijnen V C; Postmus P E; Ardizzoni A; Manegold C H; Burghouts J; van Meerbeeck J; Gans S; Mollers M; Buchholz E; Biesma B; Legrand C; Debruyne C; Giaccone G;
Reduction of chemotherapy-induced febrile leucopenia by prophylactic use of ciprofloxacin and roxithromycin in small-cell lung cancer patients: an EORTC double-blind placebo-controlled phase III study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2001;12(10):1359-68.
2001: Huisman C; Giaccone G; van Groeningen C J; Sutedja G; Postmus P E; Smit E F
Combination of gemcitabine and cisplatin for advanced non-small cell lung cancer: a phase II study with emphasis on scheduling.
Lung cancer (Amsterdam, Netherlands) 2001;33(2-3):267-75.
2001: Ferreira C G; van der Valk P; Span S W; Ludwig I; Smit E F; Kruyt F A; Pinedo H M; van Tinteren H; Giaccone G
Expression of X-linked inhibitor of apoptosis as a novel prognostic marker in radically resected non-small cell lung cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2468-74.
2001: van der Vliet H J; von Blomberg B M; Nishi N; Reijm M; Voskuyl A E; van Bodegraven A A; Polman C H; Rustemeyer T; Lips P; van den Eertwegh A J; Giaccone G; Scheper R J; Pinedo H M
Circulating V(alpha24+) Vbeta11+ NKT cell numbers are decreased in a wide variety of diseases that are characterized by autoreactive tissue damage.
Clinical immunology (Orlando, Fla.) 2001;100(2):144-8.
2001: Ferreira C G; van der Valk P; Span S W; Jonker J M; Postmus P E; Kruyt F A; Giaccone G
Assessment of IAP (inhibitor of apoptosis) proteins as predictors of response to chemotherapy in advanced non-small-cell lung cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2001;12(6):799-805.
2001: Savonije J H; Spanier B W; van Groeningen C J; Giaccone G; Pinedo H M
[Decline in the need for blood transfusions in cancer patients due to the use of epoietin alfa during cisplatin based chemotherapy]
Nederlands tijdschrift voor geneeskunde 2001;145(18):878-81.
2001: Dingemans A C; van Ark-Otte J; Span S; Scagliotti G V; van der Valk P; Postmus P E; Giaccone G
Topoisomerase IIalpha and other drug resistance markers in advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2001;32(2):117-28.
2001: Backus H H; Dukers D F; van Groeningen C J; Vos W; Bloemena E; Wouters D; van Riel J M; Smid K; Giaccone G; Pinedo H M; Peters G J
5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2001;12(2):209-16.
2001: van der Vliet HJ; Nishi N; Koezuka Y; von Blomberg BM; van den Eertwegh AJ; Porcelli S A; Pinedo H M; Scheper R J; Giaccone G
Potent expansion of human natural killer T cells using alpha-galactosylceramide (KRN7000)-loaded monocyte-derived dendritic cells, cultured in the presence of IL-7 and IL-15.
Journal of immunological methods 2001;247(1-2):61-72.
2001: Giaccone G; Smit E F
Lung cancer.
Cancer chemotherapy and biological response modifiers 2001;19():485-534.
2001: Johnson S B; Eng T Y; Giaccone G; Thomas C R
Thymoma: update for the new millennium.
The oncologist 2001;6(3):239-46.
2000: van Riel J M; van Groeningen C J; Albers S H; Cazemier M; Meijer S; Bleichrodt R; van den Berg F G; Pinedo H M; Giaccone G
Hepatic arterial 5-fluorouracil in patients with liver metastases of colorectal cancer: single-centre experience in 145 patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(12):1563-70.
2000: Ferreira C G; Span S W; Peters G J; Kruyt F A; Giaccone G
Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460.
Cancer research 2000;60(24):7133-41.
2000: van Moorsel C J; Pinedo H M; Smid K; Comijn E M; Voorn D A; Veerman G; Lakerveld B; Van der Vijgh W J; Giaccone G; Postmus P E; Peters G J
Schedule-dependent pharmacodynamic effects of gemcitabine and cisplatin in mice bearing Lewis lung murine non-small cell lung tumours.
European journal of cancer (Oxford, England : 1990) 2000;36(18):2420-9.
2000: Huisman C; Smit E F; Giaccone G; Postmus P E
Second-line chemotherapy in relapsing or refractory non-small-cell lung cancer: a review.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(21):3722-30.
2000: Padrón J M; van der Wilt C L; Smid K; Smitskamp-Wilms E; Backus H H; Pizao P E; Giaccone G; Peters G J
The multilayered postconfluent cell culture as a model for drug screening.
Critical reviews in oncology/hematology 2000;36(2-3):141-57.
2000: Meerum Terwogt J; van Tellingen O; Nannan Panday V R; Huizing M T; Schellens J H; ten Bokkel Huinink W W; Boschma M U; Giaccone G; Veenhof C H; Beijnen J H
Cremophor EL pharmacokinetics in a phase I study of paclitaxel (Taxol) and carboplatin in non-small cell lung cancer patients.
Anti-cancer drugs 2000;11(9):687-94.
2000: Postmus P E; Haaxma-Reiche H; Smit E F; Groen H J; Karnicka H; Lewinski T; van Meerbeeck J; Clerico M; Gregor A; Curran D; Sahmoud T; Kirkpatrick A; Giaccone G
Treatment of brain metastases of small-cell lung cancer: comparing teniposide and teniposide with whole-brain radiotherapy--a phase III study of the European Organization for the Research and Treatment of Cancer Lung Cancer Cooperative Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(19):3400-8.
2000: Bergman A M; Giaccone G; van Moorsel C J; Mauritz R; Noordhuis P; Pinedo H M; Peters G J
Cross-resistance in the 2',2'-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000 to standard and investigational drugs.
European journal of cancer (Oxford, England : 1990) 2000;36(15):1974-83.
2000: Kroep J R; Giaccone G; Tolis C; Voorn D A; Loves W J; Groeningen C J; Pinedo H M; Peters G J
Sequence dependent effect of paclitaxel on gemcitabine metabolism in relation to cell cycle and cytotoxicity in non-small-cell lung cancer cell lines.
British journal of cancer 2000;83(8):1069-76.
2000: Dingemans A M; Van Ark-Otte J; Smit E F; Postmus P E; Giaccone G
Validation of a polymerase chain reaction aided transcript titration assay (PATTY) for topoisomerase II in lung cancer samples.
Anticancer research 2000;20(5B):3549-54.
2000: Baars A; Claessen A M; van den Eertwegh A J; Gall H E; Stam A G; Meijer S; Giaccone G; Meijer C J; Scheper R J; Wagstaff J; Vermorken J B; Pinedo H M
Skin tests predict survival after autologous tumor cell vaccination in metastatic melanoma: experience in 81 patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(8):965-70.
2000: van Riel J M; van Groeningen C J; Giaccone G; Pinedo H M
Hepatic arterial chemotherapy for colorectal cancer metastatic to the liver.
Oncology 2000;59(2):89-97.
2000: van Groeningen C J; Peters G J; Schornagel J H; Gall H; Noordhuis P; de Vries M J; Turner S L; Swart M S; Pinedo H M; Hanauske A R; Giaccone G
Phase I clinical and pharmacokinetic study of oral S-1 in patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(14):2772-9.
2000: Van Zandwijk N; Smit E F; Kramer G W; Schramel F; Gans S; Festen J; Termeer A; Schlosser N J; Debruyne C; Curran D; Giaccone G
Gemcitabine and cisplatin as induction regimen for patients with biopsy-proven stage IIIA N2 non-small-cell lung cancer: a phase II study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group (EORTC 08955).
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(14):2658-64.
2000: Baas P; van Meerbeeck J; Groen H; Schouwink H; Burgers S; Daamen S; Giaccone G
Caelyx in malignant mesothelioma: a phase II EORTC study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(6):697-700.
2000: Linskens R K; Golding R P; van Groeningen C J; Giaccone G
Severe acute lung injury induced by gemcitabine.
The Netherlands journal of medicine 2000;56(6):232-5.
2000: Hadithi M; Weijmer M C; van den Bosch J; Giaccone G
A bone biopsy is mandatory in the optimal management of bone lesions in patients with a long-term history of malignancy of the breast.
The Netherlands journal of medicine 2000;56(6):223-8.
2000: Van Triest B; Pinedo H M; Giaccone G; Peters G J
Downstream molecular determinants of response to 5-fluorouracil and antifolate thymidylate synthase inhibitors.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(4):385-91.
2000: Nishi N; van der Vliet H J; Koezuka Y; von Blomberg B M; Scheper R J; Pinedo H M; Giaccone G
Synergistic effect of KRN7000 with interleukin-15, -7, and -2 on the expansion of human V alpha 24+V beta 11+ T cells in vitro.
Human immunology 2000;61(4):357-65.
2000: Giaccone G; Smit E F; van Meerbeeck J P; Splinter T; Golding R P; Pinedo H M; Laan D; van Tinteren H; Postmus P E
A phase I-II study of gemcitabine and paclitaxel in advanced non-small-cell lung cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(1):109-12.
2000: Ferreira C G; Tolis C; Span S W; Peters G J; van Lopik T; Kummer A J; Pinedo H M; Giaccone G
Drug-induced apoptosis in lung cnacer cells is not mediated by the Fas/FasL (CD95/APO1) signaling pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(1):203-12.
2000: Giaccone G
Treatment of thymoma and thymic carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11 Suppl 3():245-6.
1999: Van Der Vliet H J; Nishi N; Koezuka Y; Peyrat M A; Von Blomberg B M; Van Den Eertwegh A J; Pinedo H M; Giaccone G; Scheper R J
Effects of alpha-galactosylceramide (KRN7000), interleukin-12 and interleukin-7 on phenotype and cytokine profile of human Valpha24+ Vbeta11+ T cells.
Immunology 1999;98(4):557-63.
1999: Ferreira C G; Tolis C; Giaccone G
p53 and chemosensitivity.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(9):1011-21.
1999: Dingemans A M; Witlox M A; Stallaert R A; van der Valk P; Postmus P E; Giaccone G
Expression of DNA topoisomerase IIalpha and topoisomerase IIbeta genes predicts survival and response to chemotherapy in patients with small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(8):2048-58.
1999: Huisman C; Postmus P E; Giaccone G; Smit E F
Second-line chemotherapy and its evaluation in small cell lung cancer.
Cancer treatment reviews 1999;25(4):199-206.
1999: Kroep J R; Giaccone G; Voorn D A; Smit E F; Beijnen J H; Rosing H; van Moorsel C J; van Groeningen C J; Postmus P E; Pinedo H M; Peters G J
Gemcitabine and paclitaxel: pharmacokinetic and pharmacodynamic interactions in patients with non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(7):2190-7.
1999: van Meerbeeck J P; Baas P; Debruyne C; Groen H J; Manegold C; Ardizzoni A; Gridelli C; van Marck E A; Lentz M; Giaccone G
A Phase II study of gemcitabine in patients with malignant pleural mesothelioma. European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group.
Cancer 1999;85(12):2577-82.
1999: Tolis C; Peters G J; Ferreira C G; Pinedo H M; Giaccone G
Cell cycle disturbances and apoptosis induced by topotecan and gemcitabine on human lung cancer cell lines.
European journal of cancer (Oxford, England : 1990) 1999;35(5):796-807.
1999: Meersma G J; Bakker M; Groen H J; Van der Zee A G; Jensen P B; Giaccone G; De Vries E G; Smit E F
A PCR-aided transcript titration assay (PATTY) to measure topoisomerase I gene expression in human tumor specimens.
Anticancer research 1999;19(2A):1309-15.
1999: Giaccone G
Gemcitabine plus taxane combinations in non-small cell lung cancer.
Seminars in oncology 1999;26(1 Suppl 4):19-24.
1999: van Riel J M; Giaccone G; Pinedo H M
Pancreaticobiliary cancer: the future aspects of medical oncology.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10 Suppl 4():296-9.
1999: van Riel J M; van Groeningen C J; Pinedo H M; Giaccone G
Current chemotherapeutic possibilities in pancreaticobiliary cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10 Suppl 4():157-61.
1999: Honkoop A H; Luykx-de Bakker S A; Hoekman K; Meyer S; Meyer O W; van Groeningen C J; van Diest P J; Boven E; van der Wall E; Giaccone G; Wagstaff J; Pinedo H M
Prolonged neoadjuvant chemotherapy with GM-CSF in locally advanced breast cancer.
The oncologist 1999;4(2):106-11.
1998: Boven E; Pinedo H M; van Hattum A H; Scheffer P G; Peters W H; Erkelens C A; Schlüper H M; Kuiper C M; van Ark-Otte J; Giaccone G
Characterization of human soft-tissue sarcoma xenografts for use in secondary drug screening.
British journal of cancer 1998;78(12):1586-93.
1998: Dingemans A M; Pinedo H M; Giaccone G
Clinical resistance to topoisomerase-targeted drugs.
Biochimica et biophysica acta 1998;1400(1-3):275-88.
1998: Giaccone G; Manegold C; Rosell R; Gatzemeier U; Quoix E
An update on European randomized studies in non-small cell lung cancer.
Seminars in oncology 1998;25(4 Suppl 9):11-7.
1998: van Ark-Otte J; Kedde M A; van der Vijgh W J; Dingemans A M; Jansen W J; Pinedo H M; Boven E; Giaccone G
Determinants of CPT-11 and SN-38 activities in human lung cancer cells.
British journal of cancer 1998;77(12):2171-6.
1998: Giaccone G; Splinter T A; Debruyne C; Kho G S; Lianes P; van Zandwijk N; Pennucci M C; Scagliotti G; van Meerbeeck J; van Hoesel Q; Curran D; Sahmoud T; Postmus P E
Randomized study of paclitaxel-cisplatin versus cisplatin-teniposide in patients with advanced non-small-cell lung cancer. The European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(6):2133-41.
1998: Honkoop A H; van Diest P J; de Jong J S; Linn S C; Giaccone G; Hoekman K; Wagstaff J; Pinedo H M
Prognostic role of clinical, pathological and biological characteristics in patients with locally advanced breast cancer.
British journal of cancer 1998;77(4):621-6.
1998: van Ark-Otte J; Samelis G; Rubio G; Lopez Saez J B; Pinedo H M; Giaccone G
Effects of tubulin-inhibiting agents in human lung and breast cancer cell lines with different multidrug resistance phenotypes.
Oncology reports 1998;5(1):249-55.
1998: Nannan Panday V R; van Warmerdam L J; Huizing M T; Ten Bokkel Huinink W W; Vermorken J B; Giaccone G; Veenhof C H; Schellens J H; Beijnen J H
Carboplatin dosage formulae can generate inaccurate predictions of Carboplatin exposure in carboplatin/paclitaxel combination regimens.
Clinical drug investigation 1998;15(4):327-35.
1998: Jansen W J; Hulscher T M; van Ark-Otte J; Giaccone G; Pinedo H M; Boven E
CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein.
British journal of cancer 1998;77(3):359-65.
1997: Giaccone G; Linn S C; Welink J; Catimel G; Stieltjes H; van der Vijgh W J; Eeltink C; Vermorken J B; Pinedo H M
A dose-finding and pharmacokinetic study of reversal of multidrug resistance with SDZ PSC 833 in combination with doxorubicin in patients with solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(11):2005-15.
1997: Sahmoud T; Postmus P E; van Pottelsberghe C; Mattson K; Tammilehto L; Splinter T A; Planting A S; Sutedja T; van Pawel J; van Zandwijk N; Baas P; Roozendaal K J; Schrijver M; Kirkpatrick A; Van Glabbeke M; Ardizzoni A; Giaccone G
Etoposide in malignant pleural mesothelioma: two phase II trials of the EORTC Lung Cancer Cooperative Group.
European journal of cancer (Oxford, England : 1990) 1997;33(13):2211-5.
1997: van Zandwijk N; Groen H J; Postmus P E; Burghouts J T; ten Velde G P; Ardizzoni A; Smith I E; Baas P; Sahmoud T; Kirkpatrick A; Dalesio O; Giaccone G
Role of recombinant interferon-gamma maintenance in responding patients with small cell lung cancer. A randomised phase III study of the EORTC Lung Cancer Cooperative Group.
European journal of cancer (Oxford, England : 1990) 1997;33(11):1759-66.
1997: Honkoop A H; van der Wall E; Feller N; Schuurhuis G J; van der Vijgh W J; Boven E; van Groeningen C J; Giaccone G; Hoekman K; Vermorken J B; Wagstaff J; Pinedo H M
Multiple cycles of high-dose doxorubicin and cyclophosphamide with G-CSF mobilized peripheral blood progenitor cell support in patients with metastatic breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1997;8(10):957-62.
1997: Dingemans A M; Brakenhoff R H; Postmus P E; Giaccone G
Detection of cytokeratin-19 transcripts by reverse transcriptase-polymerase chain reaction in lung cancer cell lines and blood of lung cancer patients.
Laboratory investigation; a journal of technical methods and pathology 1997;77(3):213-20.
1997: Gregor A; Drings P; Burghouts J; Postmus P E; Morgan D; Sahmoud T; Kirkpatrick A; Dalesio O; Giaccone G
Randomized trial of alternating versus sequential radiotherapy/chemotherapy in limited-disease patients with small-cell lung cancer: a European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(8):2840-9.
1997: Apolinario R M; van der Valk P; de Jong J S; Deville W; van Ark-Otte J; Dingemans A M; van Mourik J C; Postmus P E; Pinedo H M; Giaccone G
Prognostic value of the expression of p53, bcl-2, and bax oncoproteins, and neovascularization in patients with radically resected non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(6):2456-66.
1997: Linn S C; Pinedo H M; van Ark-Otte J; van der Valk P; Hoekman K; Honkoop A H; Vermorken J B; Giaccone G
Expression of drug resistance proteins in breast cancer, in relation to chemotherapy.
International journal of cancer. Journal international du cancer 1997;71(5):787-95.
1997: Giaccone G; Postmus P E; Splinter T A; Diaz-Puente M; Van Zandwijk N; Scagliotti G; Ardizzoni A; Van Meerbeeck J; Debruyne C
Cisplatin/paclitaxel vs cisplatin/teniposide for advanced non-small-cell lung cancer. The EORTC Lung Cancer Cooperative Group. The European Organization for Research and Treatment of Cancer.
Oncology (Williston Park, N.Y.) 1997;11(4 Suppl 3):11-4.
1997: Jansen W J; Zwart B; Hulscher S T; Giaccone G; Pinedo H M; Boven E
CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants.
International journal of cancer. Journal international du cancer 1997;70(3):335-40.
1996: Postmus P E; Giaccone G; Debruyne C; Sahmoud T; Splinter T A; van Zandwijk N
Results of the phase II EORTC study comparing paclitaxel/cisplatin with teniposide/cisplatin in patients with non-small cell lung cancer. EORTC Lung Cancer Cooperative Group.
Seminars in oncology 1996;23(5 Suppl 12):10-3.
1996: van Meerbeeck J; Debruyne C; van Zandwijk N; Postmus P E; Pennucci M C; van Breukelen F; Galdermans D; Groen H; Pinson P; van Glabbeke M; van Marck E; Giaccone G
Paclitaxel for malignant pleural mesothelioma: a phase II study of the EORTC Lung Cancer Cooperative Group.
British journal of cancer 1996;74(6):961-3.
1996: Postmus P E; Scagliotti G; Groen H J; Gozzelino F; Burghouts J T; Curran D; Sahmoud T; Kirkpatrick A; Giaccone G; Splinter T A
Standard versus alternating non-cross-resistant chemotherapy in extensive small cell lung cancer: an EORTC Phase III trial.
European journal of cancer (Oxford, England : 1990) 1996;32A(9):1498-503.
1996: Dingemans A M; van Ark-Otte J; van der Valk P; Apolinario R M; Scheper R J; Postmus P E; Giaccone G
Expression of the human major vault protein LRP in human lung cancer samples and normal lung tissues.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7(6):625-30.
1996: Linn S C; Honkoop A H; Hoekman K; van der Valk P; Pinedo H M; Giaccone G
p53 and P-glycoprotein are often co-expressed and are associated with poor prognosis in breast cancer.
British journal of cancer 1996;74(1):63-8.
1996: Giaccone G; van Ark-Otte J; Rubio G J; Gazdar A F; Broxterman H J; Dingemans A M; Flens M J; Scheper R J; Pinedo H M
MRP is frequently expressed in human lung-cancer cell lines, in non-small-cell lung cancer and in normal lungs.
International journal of cancer. Journal international du cancer 1996;66(6):760-7.
1996: Giaccone G
New drugs for the management of lung cancer.
British journal of hospital medicine 1996;55(10):634-8.
1996: Izquierdo M A; Scheffer G L; Flens M J; Giaccone G; Broxterman H J; Meijer C J; van der Valk P; Scheper R J
Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors.
The American journal of pathology 1996;148(3):877-87.
1996: van Zandwijk N; Giaccone G
Treatment of metastatic non-small cell lung cancer.
Current opinion in oncology 1996;8(2):120-5.
1996: Giaccone G; Ardizzoni A; Kirkpatrick A; Clerico M; Sahmoud T; van Zandwijk N
Cisplatin and etoposide combination chemotherapy for locally advanced or metastatic thymoma. A phase II study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(3):814-20.
1996: Planting A; Helle P; Drings P; Dalesio O; Kirkpatrick A; McVie G; Giaccone G
A randomized study of high-dose split course radiotherapy preceded by high-dose chemotherapy versus high-dose radiotherapy only in locally advanced non-small-cell lung cancer. An EORTC Lung Cancer Cooperative Group trial.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7(2):139-44.
1996: Honkoop A H; Hoekman K; Wagstaff J; Boven E; van Groeningen C J; Giaccone G; Vermorken J B; Pinedo H M
Dose-intensive chemotherapy with doxorubicin, cyclophosphamide and GM-CSF fails to improve survival of metastatic breast cancer patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1996;7(1):35-9.
1996: Splinter T A; Sahmoud T; Festen J; van Zandwijk N; Sörenson S; Clerico M; Burghouts J; Dautzenberg B; Kho G S; Kirkpatrick A; Giaccone G
Two schedules of teniposide with or without cisplatin in advanced non-small-cell lung cancer: a randomized study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1996;14(1):127-34.
1995: Giaccone G; van Ark-Otte J; Scagliotti G; Capranico G; van der Valk P; Rubio G; Dalesio O; Lopez R; Zunino F; Walboomers J
Differential expression of DNA topoisomerases in non-small cell lung cancer and normal lung.
Biochimica et biophysica acta 1995;1264(3):337-46.
1995: Izquierdo M A; Van der Valk P; Van Ark-Otte J; Rubio G; Germa-Lluch J R; Ueda R; Scheper R J; Takahashi T; Giaccone G
Differential expression of the c-kit proto-oncogene in germ cell tumours.
The Journal of pathology 1995;177(3):253-8.
1995: Broxterman H J; Giaccone G; Lankelma J
Multidrug resistance proteins and other drug transport-related resistance to natural product agents.
Current opinion in oncology 1995;7(6):532-40.
1995: Smitskamp-Wilms E; Giaccone G; Pinedo H M; van der Laan B F; Peters G J
DT-diaphorase activity in normal and neoplastic human tissues; an indicator for sensitivity to bioreductive agents?
British journal of cancer 1995;72(4):917-21.
1995: Linn S C; Giaccone G; van Diest P J; Blokhuis W M; van der Valk P; van Kalken C K; Kuiper C M; Pinedo H M; Baak J P
Prognostic relevance of P-glycoprotein expression in breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1995;6(7):679-85.
1995: Izquierdo M A; van der Zee A G; Vermorken J B; van der Valk P; Beliën J A; Giaccone G; Scheffer G L; Flens M J; Pinedo H M; Kenemans P
Drug resistance-associated marker Lrp for prediction of response to chemotherapy and prognoses in advanced ovarian carcinoma.
Journal of the National Cancer Institute 1995;87(16):1230-7.
1995: Giaccone G; Huizing M; Postmus P E; ten Bokkel Huinink W W; Koolen M; van Zandwijk N; Vermorken J B; Beijnen J H; Dalesio O; Pinedo H M
Dose-finding and sequencing study of paclitaxel and carboplatin in non-small cell lung cancer.
Seminars in oncology 1995;22(4 Suppl 9):78-82.
1995: Linn S C; Giaccone G
MDR1/P-glycoprotein expression in colorectal cancer.
European journal of cancer (Oxford, England : 1990) 1995;31A(7-8):1291-4.
1995: Giaccone G
New drugs in non-small cell lung cancer. An overview.
Lung cancer (Amsterdam, Netherlands) 1995;12 Suppl 1():S155-62.
1995: Giaccone G; Linn S C; Pinedo H M
Multidrug resistance in breast cancer: mechanisms, strategies.
European journal of cancer (Oxford, England : 1990) 1995;31A Suppl 7():S15-7.
1995: Rubio G J; Pinedo H M; Virizuela J; van Ark-Otte J; Giaccone G
Effects of suramin on human lung cancer cell lines.
European journal of cancer (Oxford, England : 1990) 1995;31A(2):244-51.
1994: Beijnen J H; Huizing M T; ten Bokkel Huinink W W; Veenhof C H; Vermorken J B; Giaccone G; Pinedo H M
Bioanalysis, pharmacokinetics, and pharmacodynamics of the novel anticancer drug paclitaxel (Taxol).
Seminars in oncology 1994;21(5 Suppl 8):53-62.
1994: Giaccone G; Huizing M; ten Bokkel Huinink W; Koolen M; Postmus P; van Kralingen K; van Zandwijk N; Vermorken J; Beijnen J; Dalesio O
Preliminary results of two dose-finding studies of paclitaxel (Taxol) and carboplatin in non-small cell lung and ovarian cancers: a European Cancer Centre effort.
Seminars in oncology 1994;21(5 Suppl 8):34-8.
1994: Pizao P E; Smitskamp-Wilms E; Van Ark-Otte J; Beijnen J H; Peters G J; Pinedo H M; Giaccone G
Antiproliferative activity of the topoisomerase I inhibitors topotecan and camptothecin, on sub- and postconfluent tumor cell cultures.
Biochemical pharmacology 1994;48(6):1145-54.
1994: Linn S C; van Kalken C K; van Tellingen O; van der Valk P; van Groeningen C J; Kuiper C M; Pinedo H M; Giaccone G
Clinical and pharmacologic study of multidrug resistance reversal with vinblastine and bepridil.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1994;12(4):812-9.
1994: Giaccone G
DNA topoisomerases and topoisomerase inhibitors.
Pathologie-biologie 1994;42(4):346-52.
1994: Smitskamp-Wilms E; Peters G J; Pinedo H M; van Ark-Otte J; Giaccone G
Chemosensitivity to the indoloquinone EO9 is correlated with DT-diaphorase activity and its gene expression.
Biochemical pharmacology 1994;47(8):1325-32.
1994: Giaccone G
Small cell lung cancer and topoisomerases.
Anticancer research 1994;14(1B):269-76.
1994: Lopez R; Peters G J; Smitskamp-Wilms E; Virizuela J A; van Ark-Otte J; Pinedo H M; Giaccone G
In vitro sequence-dependent synergistic effect of suramin and camptothecin.
European journal of cancer (Oxford, England : 1990) 1994;30A(11):1670-4.
1993: Giaccone G; Dalesio O; McVie G J; Kirkpatrick A; Postmus P E; Burghouts J T; Bakker W; Koolen M G; Vendrik C P; Roozendaal K J
Maintenance chemotherapy in small-cell lung cancer: long-term results of a randomized trial. European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1993;11(7):1230-40.
1993: Clerico M; Bertetto O; Morandini M P; Cardinali C; Giaccone G
Antiemetic activity of oral lorazepam in addition to methylprednisolone and metoclopramide in the prophylactic treatment of vomiting induced by cisplatin. A double-blind, placebo-controlled study with crossover design.
Tumori 1993;79(2):119-22.
1993: van Kalken C K; Broxterman H J; Pinedo H M; Feller N; Dekker H; Lankelma J; Giaccone G
Cortisol is transported by the multidrug resistance gene product P-glycoprotein.
British journal of cancer 1993;67(2):284-9.
1993: Pizao P E; Peters G J; Van Ark-Otte J; Smets L A; Smitskamp-Wilms E; Winograd B; Pinedo H M; Giaccone G
Cytotoxic effects of anticancer agents on subconfluent and multilayered postconfluent cultures.
European journal of cancer (Oxford, England : 1990) 1993;29A(11):1566-73.
1992: van Kalken C K; Giaccone G; van der Valk P; Kuiper C M; Hadisaputro M M; Bosma S A; Scheper R J; Meijer C J; Pinedo H M
Multidrug resistance gene (P-glycoprotein) expression in the human fetus.
The American journal of pathology 1992;141(5):1063-72.
1992: Pizao P E; Lyaruu D M; Peters G J; van Ark-Otte J; Winograd B; Giaccone G; Pinedo H M
Growth, morphology and chemosensitivity studies on postconfluent cells cultured in 'V'-bottomed microtiter plates.
British journal of cancer 1992;66(4):660-5.
1992: Pizao P E; Winograd B; Peters G J; Leyva A; Giaccone G; Pinedo H M
In vitro chemosensitivity testing of multilayered microcultures.
Anticancer research 1992;12(4):1319-22.
1992: Mattson K; Giaccone G; Kirkpatrick A; Evrard D; Tammilehto L; van Breukelen F J; Planteydt H T; van Zandwijk N
Epirubicin in malignant mesothelioma: a phase II study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(5):824-8.
1992: Giaccone G; Splinter T A; Kirkpatrick A; Dalesio O; van Zandwijk N; McVie J G
The European Organization for Research and Treatment of Cancer experience with teniposide: preliminary results of a randomized study in non-small cell lung cancer.
Seminars in oncology 1992;19(2 Suppl 6):98-102.
1992: Giaccone G
Teniposide alone and in combination chemotherapy in small cell lung cancer.
Seminars in oncology 1992;19(2 Suppl 6):75-80.
1992: Quoix E A; Giaccone G; Jassem J; Karnicka H; Wiatr E; Cortes-Funes H; Roozendaal K J; Kirkpatrick A; Evrard D; van Zandwijk N
Epirubicin in previously untreated patients with small cell lung cancer: a phase II study by the EORTC Lung Cancer Cooperative Group.
European journal of cancer (Oxford, England : 1990) 1992;28A(10):1667-70.
1991: Giaccone G; Schmidt G; Calciati A
Pilot study of teniposide in combination chemotherapy for small cell lung cancer.
European journal of cancer (Oxford, England : 1990) 1991;27(2):141-3.
1991: van Kalken C K; van der Hoeven J J; de Jong J; Giaccone G; Schuurhuis G J; Maessen P A; Blokhuis W M; van der Vijgh W J; Pinedo H M
Bepridil in combination with anthracyclines to reverse anthracycline resistance in cancer patients.
European journal of cancer (Oxford, England : 1990) 1991;27(6):739-44.
1991: van Breukelen F J; Mattson K; Giaccone G; van Zandwijk N; Planteydt H T; Kirkpatrick A; Dalesio O
Mitoxantrone in malignant pleural mesothelioma: a study by the EORTC Lung Cancer Cooperative Group.
European journal of cancer (Oxford, England : 1990) 1991;27(12):1627-9.
1991: van Kalken C K; Pinedo H M; Giaccone G
Multidrug resistance from the clinical point of view.
European journal of cancer (Oxford, England : 1990) 1991;27(11):1481-6.
1991: Iberti V; Donadio M; Giaccone G
Cisplatin and teniposide chemotherapy for advanced non-small cell lung cancer.
European journal of cancer (Oxford, England : 1990) 1991;27(9):1104-6.
1991: Giaccone G; Iberti V; Donadio M; Testore F
Mitomycin C, teniposide, and cisplatin combination chemotherapy for advanced non-small-cell carcinoma of the lung.
Cancer chemotherapy and pharmacology 1991;28(2):147-9.
1990: Giaccone G; Donadio M; Bonardi G; Iberti V; Calciati A
4'-EPI-doxorubicin in advanced lung cancer. A phase II trial.
Investigational new drugs 1990;8(4):393-6.
1990: Giaccone G; Donadio M; Bonardi G; Testore F; Calciati A
Doxorubicin and etoposide in the treatment of advanced measurable breast cancer.
Oncology 1990;47(2):105-8.
1989: Giaccone G; Bagatella M; Donadio M; Calciati A
Phase II study of divided-dose vinblastine in advanced cancer patients.
Tumori 1989;75(3):248-51.
1989: Anderson G; Clavel M; Smyth J; Giaccone G; Gracia M; Planting A S; Dalesio O; Kirkpatrick A; McVie G
Phase II study of 9-hydroxy-2-methyl-ellipticinium acetate (ellipticinium) in patients with advanced carcinoma of the lung. EORTC Lung Cancer Cooperative Group.
European journal of cancer & clinical oncology 1989;25(5):909-10.
1989: Bonardi G; Donadio M; Maestroni F; Giaccone G; Calciati A
Isolated central nervous system metastasis from ovarian carcinoma: a case report.
Tumori 1989;75(2):181-2.
1989: Giaccone G
Identification of new drugs in pretreated patients with small cell lung cancer.
European journal of cancer & clinical oncology 1989;25(3):411-3.
1989: Giaccone G; Donadio M; Bonardi G; Silvestro L; Viano I; Cotevino G; Vinzio M; Genazzani E; Calciati A
Phase II study of alpha-interferon plus bleomycin in advanced non-small cell lung cancer.
Anticancer research 1989;9(2):405-8.
1989: Giaccone G; Bagatella M; Donadio M; Bonardi G; Maestroni F; Calciati A
Lonidamine versus polychemotherapy in advanced non-small-cell lung cancer. A preliminary analysis.
Tumori 1989;75(1):43-6.
1989: Giaccone G; Donadio M; Calciati A
Phase II study of esorubicin in the treatment of patients with advanced sarcoma.
Oncology 1989;46(5):285-7.
1988: Giaccone G; Donadio M; Bonardi G; Testore F; Calciati A
Teniposide in the treatment of small-cell lung cancer: the influence of prior chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1988;6(8):1264-70.
1988: Giaccone G; Donadio M; Ferrati P; Calciati A
Cisplatin and etoposide in chemotherapy-refractory advanced breast cancer.
Tumori 1988;74(2):191-3.
1988: Giaccone G; Donadio M; Bonardi G M; Testore F; Calciati A
Teniposide (VM26): an effective treatment for brain metastases of small cell carcinoma of the lung.
European journal of cancer & clinical oncology 1988;24(4):629-31.
1988: Giaccone G; Bertetto O; Secat M A; Calciati A
High doses of methylprednisolone with or without alizapride in the prevention of cisplatin-induced emesis. A randomized, double-blind, crossover study.
Oncology 1988;45(2):74-8.
1988: Giaccone G; Bagatella M; Bertetto O; Donadio M; Calciati A
Phase II study of divided-dose vinblastine in advanced breast cancer patients.
Cancer chemotherapy and pharmacology 1988;21(1):65-7.
1987: Giaccone G; Ferrati P; Donadio M; Testore F; Calciati A
Reinduction chemotherapy in small cell lung cancer.
European journal of cancer & clinical oncology 1987;23(11):1697-9.
1987: Giaccone G; Bagatella M; Donadio M; Bonardi G M; Testore F; Ferrati P; Ciuffreda L; Calciati A
Mitomycin C, vinblastine and cis-platin. An active regimen for advanced non-small cell lung cancer.
British journal of cancer 1987;56(4):475-8.
1987: Giaccone G; Donadio M; Bonardi G; Bagatella M; Calciati A
4'-Deoxydoxorubicin, an inactive drug in small cell lung cancer.
European journal of cancer & clinical oncology 1987;23(9):1407-8.
1987: Giaccone G; Donadio M; Ferrati P; Bonardi G; Ciuffreda L; Bagatella M; Calciati A
Teniposide in the treatment of non-small cell lung carcinoma.
Cancer treatment reports 1987;71(1):83-5.
1987: Giaccone G; Ciuffreda L; Donadio M; Ferrati P; Risio M; Leria G; Bonardi G; Calciati A
Bone marrow evaluation in small cell carcinoma of the lung.
Acta oncologica (Stockholm, Sweden) 1987;26(3):185-8.
1986: Maggi G; Giaccone G; Donadio M; Ciuffreda L; Dalesio O; Leria G; Trifiletti G; Casadio C; Palestro G; Mancuso M
Thymomas. A review of 169 cases, with particular reference to results of surgical treatment.
Cancer 1986;58(3):765-76.
1986: Giaccone G; Bonardi G; Leria G; Donadio M; Calciati A
Long-term survival and complete response to adriamycin and etoposide in a case of hepatocellular carcinoma.
Tumori 1986;72(4):409-11.
1986: Giaccone G; Risio M; Bonardi G; Calciati A
Stevens-Johnson syndrome and fatal pulmonary toxicity to combination chemotherapy containing bleomycin: a case report.
Tumori 1986;72(3):331-3.
1985: Giaccone G; Musella R; Bertetto O; Donadio M; Calciati A
Cisplatin-containing chemotherapy in the treatment of invasive thymoma: report of five cases.
Cancer treatment reports 1985;69(6):695-7.
1985: Giaccone G; Donadio M; Ferrati P; Ciuffreda L; Bagatella M; Gaddi M; Calciati A
Disorders of serum electrolytes and renal function in patients treated with cis-platinum on an outpatient basis.
European journal of cancer & clinical oncology 1985;21(4):433-7.
1984: Giaccone G; Donadio M; Musella R; Bertetto O; Ciuffreda L; Ferrati P; Clerico M; Calciati A
Comparison of methylprednisolone and metoclopramide in the prophylactic treatment of cis-platin-induced nausea and vomiting.
Tumori 1984;70(3):237-41.
1983: Musella R; Giaccone G; D'Ambrosio E; Calciati A
Father-son testicular cancer, case report.
Tumori 1983;69(3):269-70.
1981: Conte P F; Giaccone G; Musella R; Calciati A
Combination chemotherapy for metastatic brain tumors.
Tumori 1981;67(6):559-62.

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