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Robertina Giacconi
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50
Mocchegiani, Eugenio
36
Cipriano, Catia
33
Malavolta, Marco
22
Costarelli, Laura
22
Muti, Elisa
14
Muzzioli, Mario
14
Gasparini, Nazzarena
6
Saba, Vittorio
5
Monti, Daniela
4
Mariani, Erminia
4
Rink, Lothar
4
Tesei, Silvia
4
Jajte, Jolanta
4
Lio, Domenico
4
Caruso, Calogero
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Geonetwork of Robertina Giacconi (preview)
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All Publications
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2009: Piacenza Francesco; Malavolta Marco; Cipriano Catia; Costarelli Laura; Giacconi Robertina; Muti Elisa; Tesei Silvia; Pierpaoli Sara; Basso Andrea; Bracci Massimo; Bonacucina Viviana; Santarelli Lory; Mocchegiani Eugenio
l-Arginine normalizes NOS activity and zinc-MT homeostasis in the kidney of mice chronically exposed to inorganic mercury.
Toxicology letters 2009;189(3):200-5.
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2009: Mocchegiani Eugenio; Giacconi Robertina; Cipriano Catia; Malavolta Marco
NK and NKT cells in aging and longevity: role of zinc and metallothioneins.
Journal of clinical immunology 2009;29(4):416-25.
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2009: Cipriano Catia; Tesei Silvia; Malavolta Marco; Giacconi Robertina; Muti Elisa; Costarelli Laura; Piacenza Francesco; Pierpaoli Sara; Galeazzi Roberta; Blasco Maria; Vera Elsa; Canela Andres; Lattanzio Fabrizia; Mocchegiani Eugenio
Accumulation of cells with short telomeres is associated with impaired zinc homeostasis and inflammation in old hypertensive participants.
The journals of gerontology. Series A, Biological sciences and medical sciences 2009;64(7):745-51.
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2008: Giacconi Robertina; Caruso Calogero; Malavolta Marco; Lio Domenico; Balistreri Carmela R; Scola Letizia; Candore Giuseppina; Muti Elisa; Mocchegiani Eugenio
Pro-inflammatory genetic background and zinc status in old atherosclerotic subjects.
Ageing research reviews 2008;7(4):306-18.
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2008: Mocchegiani Eugenio; Giacconi Robertina; Malavolta Marco
Zinc signalling and subcellular distribution: emerging targets in type 2 diabetes.
Trends in molecular medicine 2008;14(10):419-28.
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2008: Mazzatti D J; Malavolta M; White A J; Costarelli L; Giacconi R; Muti E; Cipriano C; Powell J R; Mocchegiani E
Effects of interleukin-6 -174C/G and metallothionein 1A +647A/C single-nucleotide polymorphisms on zinc-regulated gene expression in ageing.
Experimental gerontology 2008;43(5):423-32.
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2008: Mocchegiani Eugenio; Giacconi Robertina; Costarelli Laura; Muti Elisa; Cipriano Catia; Tesei Silvia; Pierpaoli Sara; Giuli Cinzia; Papa Roberta; Marcellini Fiorella; Gasparini Nazzarena; Pierandrei Romeo; Piacenza Francesco; Mariani Ermina; Monti Daniela; Dedoussis George; Kanoni Stavroula; Herbein Georges; Fulop Tamas; Rink Lothar; Jajte Jolanta; Malavolta Marco
Zinc deficiency and IL-6 -174G/C polymorphism in old people from different European countries: effect of zinc supplementation. ZINCAGE study.
Experimental gerontology 2008;43(5):433-44.
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2008: Giacconi R; Bonfigli A R; Testa R; Sirolla C; Cipriano C; Marra M; Muti E; Malavolta M; Costarelli L; Piacenza F; Tesei S; Mocchegiani E
+647 A/C and +1245 MT1A polymorphisms in the susceptibility of diabetes mellitus and cardiovascular complications.
Molecular genetics and metabolism 2008;94(1):98-104.
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2008: Malavolta Marco; Cipriano Catia; Costarelli Laura; Giacconi Robertina; Tesei Silvia; Muti Elisa; Piacenza Francesco; Pierpaoli Sara; Larbi Annis; Pawelec Graham; Dedoussis George; Herbein George; Monti Daniela; Jajte Jolanta; Rink Lothar; Mocchegiani Eugenio
Metallothionein downregulation in very old age: a phenomenon associated with cellular senescence?
Rejuvenation research 2008;11(2):455-9.
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2008: Costarelli Laura; Muti Elisa; Malavolta Marco; Giacconi Robertina; Cipriano Catia; Sartini Davide; Emanuelli Monica; Silvestrini Mauro; Provinciali Leandro; Gobbi Beatrice; Mocchegiani Eugenio
Modulation of genes involved in zinc homeostasis in old low-grade atherosclerotic patients under effects of HMG-CoA reductase inhibitors.
Rejuvenation research 2008;11(2):287-91.
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2008: Marcellini Fiorella; Giuli Cinzia; Papa Roberta; Gagliardi Cristina; Dedoussis George; Monti Daniela; Jajte Jolanta; Giacconi Robertina; Malavolta Marco; Mocchegiani Eugenio
Zinc in elderly people: effects of zinc supplementation on psychological dimensions in dependence of IL-6 -174 polymorphism: a Zincage study.
Rejuvenation research 2008;11(2):479-83.
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2008: Giacconi Robertina; Muti Elisa; Malavolta Marco; Cardelli Maurizio; Pierpaoli Sara; Cipriano Catia; Costarelli Laura; Tesei Silvia; Saba Vittorio; Mocchegiani Eugenio
A novel Zip2 Gln/Arg/Leu codon 2 polymorphism is associated with carotid artery disease in aging.
Rejuvenation research 2008;11(2):297-300.
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2008: Mocchegiani E; Malavolta M; Muti E; Costarelli L; Cipriano C; Piacenza F; Tesei S; Giacconi R; Lattanzio F
Zinc, metallothioneins and longevity: interrelationships with niacin and selenium.
Current pharmaceutical design 2008;14(26):2719-32.
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2007: Mazzatti D J; Malavolta M; White A J; Costarelli L; Giacconi R; Muti E; Cipriano C; Powell J R; Mocchegiani E
Differential effects of in vitro zinc treatment on gene expression in peripheral blood mononuclear cells derived from young and elderly individuals.
Rejuvenation research 2007;10(4):603-20.
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2007: Mocchegiani Eugenio; Giacconi Robertina; Cipriano Catia; Costarelli Laura; Muti Elisa; Tesei Silvia; Giuli Cinzia; Papa Roberta; Marcellini Fiorella; Mariani Erminia; Rink Lothar; Herbein George; Varin Audrey; Fulop Tamas; Monti Daniela; Jajte Jolanta; Dedoussis George; Gonos Efstathios S; Trougakos Ioannis P; Malavolta Marco
Zinc, metallothioneins, and longevity--effect of zinc supplementation: zincage study.
Annals of the New York Academy of Sciences 2007;1119():129-46.
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2007: Mocchegiani E; Giacconi R; Cipriano C; Malavolta M
Chronobiology and effects of the age on the immune function: nutritional and genetic background.
Veterinary research communications 2007;31 Suppl 1():109-13.
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2007: Giacconi Robertina; Caruso Calogero; Lio Domenico; Muti Elisa; Cipriano Catia; Costarelli Laura; Saba Vittorio; Gasparini Nazzarena; Malavolta Marco; Mocchegiani Eugenio
CD14 C (-260)T polymorphism, atherosclerosis, elderly: role of cytokines and metallothioneins.
International journal of cardiology 2007;120(1):45-51.
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2007: Giacconi Robertina; Muti Elisa; Malavolta Marco; Cipriano Catia; Costarelli Laura; Bernardini Gianni; Gasparini Nazzarena; Mariani Erminia; Saba Vittorio; Boccoli Gianfranco; Mocchegiani Eugenio
The +838 C/G MT2A polymorphism, metals, and the inflammatory/immune response in carotid artery stenosis in elderly people.
Molecular medicine (Cambridge, Mass.) 2007;13(7-8):388-95.
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2007: Mocchegiani Eugenio; Giacconi Robertina; Muti Elisa; Cipriano Catia; Costarelli Laura; Tesei Silvia; Gasparini Nazzarena; Malavolta Marco
Zinc-bound metallothioneins and immune plasticity: lessons from very old mice and humans.
Immunity & ageing : I & A 2007;4():7.
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2006: Mocchegiani Eugenio; Costarelli Laura; Giacconi Robertina; Cipriano Catia; Muti Elisa; Malavolta Marco
Zinc-binding proteins (metallothionein and alpha-2 macroglobulin) and immunosenescence.
Experimental gerontology 2006;41(11):1094-107.
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2006: Malavolta Marco; Costarelli Laura; Giacconi Robertina; Muti Elisa; Bernardini Gianni; Tesei Silvia; Cipriano Catia; Mocchegiani Eugenio
Single and three-color flow cytometry assay for intracellular zinc ion availability in human lymphocytes with Zinpyr-1 and double immunofluorescence: relationship with metallothioneins.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2006;69(10):1043-53.
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2006: Vasto Sonya; Mocchegiani Eugenio; Candore Giuseppina; Listì Florinda; Colonna-Romano Giuseppina; Lio Domenico; Malavolta Marco; Giacconi Robertina; Cipriano Catia; Caruso Calogero
Inflammation, genes and zinc in ageing and age-related diseases.
Biogerontology 2006;7(5-6):315-27.
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2006: Cipriano Catia; Malavolta Marco; Costarelli Laura; Giacconi Robertina; Muti Elisa; Gasparini Nazzarena; Cardelli Maurizio; Monti Daniela; Mariani Erminia; Mocchegiani Eugenio
Polymorphisms in MT1a gene coding region are associated with longevity in Italian Central female population.
Biogerontology 2006;7(5-6):357-65.
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2006: Giacconi Robertina; Cipriano Catia; Muti Elisa; Costarelli Laura; Malavolta Marco; Caruso Calogero; Lio Domenico; Mocchegiani Eugenio
Involvement of -308 TNF-alpha and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients.
Biogerontology 2006;7(5-6):347-56.
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2006: Mocchegiani Eugenio; Santarelli Lory; Costarelli Laura; Cipriano Catia; Muti Elisa; Giacconi Robertina; Malavolta Marco
Plasticity of neuroendocrine-thymus interactions during ontogeny and ageing: role of zinc and arginine.
Ageing research reviews 2006;5(3):281-309.
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2006: Mocchegiani Eugenio; Costarelli Laura; Giacconi Robertina; Cipriano Catia; Muti Elisa; Tesei Silvia; Malavolta Marco
Nutrient-gene interaction in ageing and successful ageing. A single nutrient (zinc) and some target genes related to inflammatory/immune response.
Mechanisms of ageing and development 2006;127(6):517-25.
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2006: Crivello Antonio; Giacalone Antonio; Scola Letizia; Forte Giusi Irma; Nuzzo Domenico; Giacconi Robertina; Cipriano Catia; Candore Giuseppina; Mocchegiani Eugenio; Colonna-Romano Giuseppina; Lio Domenico; Caruso Calogero
Frequency of polymorphisms of signal peptide of TGF-beta1 and -1082G/A SNP at the promoter region of Il-10 gene in patients with carotid stenosis.
Annals of the New York Academy of Sciences 2006;1067():288-93.
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2006: Mocchegiani Eugenio; Costarelli Laura; Giacconi Robertina; Cipriano Catia; Muti Elisa; Rink Lothar; Malavolta Marco
Zinc homeostasis in aging: two elusive faces of the same "metal".
Rejuvenation research 2006;9(2):351-4.
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2005: Giacconi Robertina; Cipriano Catia; Muti Elisa; Costarelli Laura; Maurizio Cardelli; Saba Vittorio; Gasparini Nazzarena; Malavolta Marco; Mocchegiani Eugenio
Novel -209A/G MT2A polymorphism in old patients with type 2 diabetes and atherosclerosis: relationship with inflammation (IL-6) and zinc.
Biogerontology 2005;6(6):407-13.
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2005: Giacconi Robertina; Caruso Calogero; Lio Domenico; Muti Elisa; Cipriano Catia; Saba Vittorio; Boccoli Gianfranco; Gasparini Nazzarena; Malavolta Marco; Mocchegiani Eugenio
1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients.
Mechanisms of ageing and development 2005;126(8):866-73.
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2005: Cipriano C; Caruso C; Lio D; Giacconi R; Malavolta M; Muti E; Gasparini N; Franceschi C; Mocchegiani E
The -308G/A polymorphism of TNF-alpha influences immunological parameters in old subjects affected by infectious diseases.
International journal of immunogenetics 2005;32(1):13-8.
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2005: Moroni Fausto; Di Paolo Maria Luisa; Rigo Adelio; Cipriano Catia; Giacconi Robertina; Recchioni Rina; Marcheselli Fiorella; Malavolta Marco; Mocchegiani Eugenio
Interrelationship among neutrophil efficiency, inflammation, antioxidant activity and zinc pool in very old age.
Biogerontology 2005;6(4):271-81.
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2004: Ambra Roberto; Mocchegiani Eugenio; Giacconi Robertina; Canali Raffaella; Rinna Alessandra; Malavolta Marco; Virgili Fabio
Characterization of the hsp70 response in lymphoblasts from aged and centenarian subjects and differential effects of in vitro zinc supplementation.
Experimental gerontology 2004;39(10):1475-84.
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2004: Mocchegiani Eugenio; Giacconi Robertina; Muti Elisa; Rogo Cinzia; Bracci Massimo; Muzzioli Mario; Cipriano Catia; Malavolta Marco
Zinc, immune plasticity, aging, and successful aging: role of metallothionein.
Annals of the New York Academy of Sciences 2004;1019():127-34.
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2004: Mocchegiani Eugenio; Giacconi Robertina; Cipriano Catia; Gasparini Nazzarena; Bernardini Gianni; Malavolta Marco; Menegazzi Marta; Cavalieri Elisabetta; Muzzioli Mario; Ciampa Anna Rosa; Suzuki Hisanori
The variations during the circadian cycle of liver CD1d-unrestricted NK1.1+TCR gamma/delta+ cells lead to successful ageing. Role of metallothionein/IL-6/gp130/PARP-1 interplay in very old mice.
Experimental gerontology 2004;39(5):775-88.
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2004: Giacconi Robertina; Cipriano Catia; Albanese Francesco; Boccoli Gianfranco; Saba Vittorio; Olivieri Fabiola; Franceschi Claudio; Mocchegiani Eugenio
The -174G/C polymorphism of IL-6 is useful to screen old subjects at risk for atherosclerosis or to reach successful ageing.
Experimental gerontology 2004;39(4):621-8.
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2004: Mocchegiani Eugenio; Giacconi Robertina; Fattoretti Patrizia; Casoli Tiziana; Cipriano Catia; Muti Elisa; Malavolta Marco; DiStefano Giuseppina; Bertoni-Freddari Carlo
Metallothionein isoforms (I+II and III) and interleukin-6 in the hippocampus of old rats: may their concomitant increments lead to neurodegeneration?
Brain research bulletin 2004;63(2):133-42.
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2003: Cipriano Catia; Giacconi Robertina; Muzzioli Mario; Gasparini Nazzarena; Orlando Fiorenza; Corradi Attilio; Cabassi Enrico; Mocchegiani Eugenio
Metallothionein (I+II) confers, via c-myc, immune plasticity in oldest mice: model of partial hepatectomy/liver regeneration.
Mechanisms of ageing and development 2003;124(8-9):877-86.
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2003: Mocchegiani Eugenio; Muzzioli Mario; Giacconi Robertina; Cipriano Catia; Gasparini Nazzarena; Franceschi Claudio; Gaetti Remo; Cavalieri Elisabetta; Suzuki Hisanori
Metallothioneins/PARP-1/IL-6 interplay on natural killer cell activity in elderly: parallelism with nonagenarians and old infected humans. Effect of zinc supply.
Mechanisms of ageing and development 2003;124(4):459-68.
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2003: Giacconi Robertina; Cipriano Catia; Muzzioli Mario; Gasparini Nazzarena; Orlando Florenza; Mocchegiani Eugenio
Interrelationships among brain, endocrine and immune response in ageing and successful ageing: role of metallothionein III isoform.
Mechanisms of ageing and development 2003;124(4):371-8.
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2002: Mocchegiani Eugenio; Giacconi Robertina; Cipriano Catia; Gasparini Nazzarena; Orlando Fiorenza; Stecconi Rosalia; Muzzioli Mario; Isani Gloria; Carpenè Emilio
Metallothioneins (I+II) and thyroid-thymus axis efficiency in old mice: role of corticosterone and zinc supply.
Mechanisms of ageing and development 2002;123(6):675-94.
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2002: Mocchegiani Eugenio; Giacconi Robertina; Cipriano Catia; Muzzioli Mario; Gasparini Nazzarena; Moresi Raffaella; Stecconi Rosalia; Suzuki Hisanori; Cavalieri Elisabetta; Mariani Erminia
MtmRNA gene expression, via IL-6 and glucocorticoids, as potential genetic marker of immunosenescence: lessons from very old mice and humans.
Experimental gerontology 2002;37(2-3):349-57.
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2001: Mocchegiani E; Giacconi R; Cipriano C; Muzzioli M; Fattoretti P; Bertoni-Freddari C; Isani G; Zambenedetti P; Zatta P
Zinc-bound metallothioneins as potential biological markers of ageing.
Brain research bulletin 2001;55(2):147-53.
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2000: Mocchegiani E; Giacconi R; Muzzioli M; Cipriano C
Zinc, infections and immunosenescence.
Mechanisms of ageing and development 2000;121(1-3):21-35.
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2000: Mocchegiani E; Giacconi R; Muzzioli M; Gasparini N; Provinciali L; Spazzafumo L; Licastro F
Different age-related effects of thymectomy in myasthenia gravis: role of thymoma, zinc, thymulin, IL-2 and IL-6.
Mechanisms of ageing and development 2000;117(1-3):79-91.
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2000: Mocchegiani E; Muzzioli M; Giacconi R
Zinc and immunoresistance to infection in aging: new biological tools.
Trends in pharmacological sciences 2000;21(6):205-8.
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2000: Mocchegiani E; Muzzioli M; Giacconi R
Zinc, metallothioneins, immune responses, survival and ageing.
Biogerontology 2000;1(2):133-43.
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1999: Mocchegiani E; Perissin L; Santarelli L; Tibaldi A; Zorzet S; Rapozzi V; Giacconi R; Bulian D; Giraldi T
Melatonin administration in tumor-bearing mice (intact and pinealectomized) in relation to stress, zinc, thymulin and IL-2.
International journal of immunopharmacology 1999;21(1):27-46.
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1999: Mocchegiani E; Ciavattini A; Santarelli L; Tibaldi A; Muzzioli M; Bonazzi P; Giacconi R; Fabris N; Garzetti G G
Role of zinc and alpha2 macroglobulin on thymic endocrine activity and on peripheral immune efficiency (natural killer activity and interleukin 2) in cervical carcinoma.
British journal of cancer 1999;79(2):244-50.
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1998: Mocchegiani E; Muzzioli M; Cipriano C; Giacconi R
Zinc, T-cell pathways, aging: role of metallothioneins.
Mechanisms of ageing and development 1998;106(1-2):183-204.
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