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Ezio Giacobini

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Disorders

Alzheimer Disease

Chemicals & Drugs

Anatomy

Living Beings

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Co-Publications
Name
12
Marchi, Mario
5
Kerpel-Fronius, Sándor
4
Lahiri, Debomoy
4
Michel, Jean-Pierre
3
Elble, Rodger
3
Maelicke, Alfred
3
Manyam, Bala
3
Sugaya, Kiminobu
2
Gold, Gabriel
2
Greig, Nigel
2
Zekry, Dina
2
Brufani, M
1
Cutler, Neal
1
de Leon, Mony
1
de Ribaupierre, Anik

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Publications

TOP 3
Martínez Ana; Lahiri Debomoy K; Giacobini Ezio; Greig Nigel H
Advances in Alzheimer therapy: understanding pharmacological approaches to the disease.
Becker Robert E; Greig Nigel H; Giacobini Ezio
Why do so many drugs for Alzheimer's disease fail in development? Time for new methods and new practices?
Greig Nigel H; Giacobini Ezio; Lahiri Debomoy K
Advances in Alzheimer therapy: development of innovative new strategies.

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All Publications

2009: Martínez Ana; Lahiri Debomoy K; Giacobini Ezio; Greig Nigel H
Advances in Alzheimer therapy: understanding pharmacological approaches to the disease.
Current Alzheimer research 2009;6(2):83-5.
2008: Becker Robert E; Greig Nigel H; Giacobini Ezio
Why do so many drugs for Alzheimer's disease fail in development? Time for new methods and new practices?
Journal of Alzheimer's disease : JAD 2008;15(2):303-25.
2007: Greig Nigel H; Giacobini Ezio; Lahiri Debomoy K
Advances in Alzheimer therapy: development of innovative new strategies.
Current Alzheimer research 2007;4(4):336-9.
2007: Giacobini Ezio; Becker Robert E
One hundred years after the discovery of Alzheimer's disease. A turning point for therapy?
Journal of Alzheimer's disease : JAD 2007;12(1):37-52.
2005: Onder Graziano; Zanetti Orazio; Giacobini Ezio; Frisoni Giovanni B; Bartorelli Luisa; Carbone Gabriele; Lambertucci Paola; Silveri Maria Caterina; Bernabei Roberto
Reality orientation therapy combined with cholinesterase inhibitors in Alzheimer's disease: randomised controlled trial.
The British journal of psychiatry : the journal of mental science 2005;187():450-5.
2005: Greig Nigel H; Lahiri Debomoy K; Giacobini Ezio
Editorial: advances in Alzheimer therapy: something old, something new, something borrowed, something blue.
Current Alzheimer research 2005;2(3):275-9.
2005: Bonin-Guillaume Sylvie; Zekry Dina; Giacobini Ezio; Gold Gabriel; Michel Jean-Pierre
[The economical impact of dementia]
Presse médicale (Paris, France : 1983) 2005;34(1):35-41.
2004: Giacobini Ezio
Cholinesterase inhibitors: new roles and therapeutic alternatives.
Pharmacological research : the official journal of the Italian Pharmacological Society 2004;50(4):433-40.
2004: Winblad B; Palmer K; Kivipelto M; Jelic V; Fratiglioni L; Wahlund L-O; Nordberg A; Bäckman L; Albert M; Almkvist O; Arai H; Basun H; Blennow K; de Leon M; DeCarli C; Erkinjuntti T; Giacobini E; Graff C; Hardy J; Jack C; Jorm A; Ritchie K; van Duijn C; Visser P; Petersen R C
Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment.
Journal of internal medicine 2004;256(3):240-6.
2003: Giacobini Ezio
Cholinergic function and Alzheimer's disease.
International journal of geriatric psychiatry 2003;18(Suppl 1):S1-5.
2003: Giacobini Ezio
Cholinesterases: new roles in brain function and in Alzheimer's disease.
Neurochemical research 2003;28(3-4):515-22.
2003: Lahiri Debomoy K; Farlow Martin R; Sambamurti Kumar; Greig Nigel H; Giacobini Ezio; Schneider Lon S
A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease.
Current drug targets 2003;4(2):97-112.
2002: Giacobini Ezio; Spiegel R; Enz A; Veroff A E; Cutler N R
Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit.
Journal of neural transmission (Vienna, Austria : 1996) 2002;109(7-8):1053-65.
2002: Giacobini E
Long-term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer' disease.
Journal of neural transmission. Supplementum 2002;(62):181-7.
2001: Slosman D O; Ludwig C; Zerarka S; Pellerin L; Chicherio C; de Ribaupierre A; Annoni J M; Bouras C; Herrmann F; Michel J P; Giacobini E; Magistretti P J
Brain energy metabolism in Alzheimer's disease: 99mTc-HMPAO SPECT imaging during verbal fluency and role of astrocytes in the cellular mechanism of 99mTc-HMPAO retention.
Brain research. Brain research reviews 2001;36(2-3):230-40.
2001: Michel J P; Zekry D; Mulligan R; Giacobini E; Gold G
Economic considerations of Alzheimer's disease and related disorders.
Aging (Milan, Italy) 2001;13(3):255-60.
2001: Giacobini E
Is anti-cholinesterase therapy of Alzheimer's disease delaying progression?
Aging (Milan, Italy) 2001;13(3):247-54.
2001: Giacobini E
Selective inhibitors of butyrylcholinesterase: a valid alternative for therapy of Alzheimer's disease?
Drugs & aging 2001;18(12):891-8.
2001: Giacobini E
Do cholinesterase inhibitors have disease-modifying effects in Alzheimer's disease?
CNS drugs 2001;15(2):85-91.
2000: Giacobini E
Cholinesterase inhibitors stabilize Alzheimer disease.
Neurochemical research 2000;25(9-10):1185-90.
2000: Giacobini E
Cholinesterase inhibitors stabilize Alzheimer's disease.
Annals of the New York Academy of Sciences 2000;920():321-7.
2000: Giacobini E
Present and future of Alzheimer therapy.
Journal of neural transmission. Supplementum 2000;59():231-42.
2000: Giacobini E
Cholinesterase inhibitor therapy stabilizes symptoms of Alzheimer disease.
Alzheimer disease and associated disorders 2000;14 Suppl 1():S3-10.
1999: Wevers A; Monteggia L; Nowacki S; Bloch W; Schütz U; Lindstrom J; Pereira E F; Eisenberg H; Giacobini E; de Vos R A; Steur E N; Maelicke A; Albuquerque E X; Schröder H
Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein.
The European journal of neuroscience 1999;11(7):2551-65.
1998: Giacobini E
Aging, Alzheimer's disease, and estrogen therapy.
Experimental gerontology 1998;33(7-8):865-9.
1998: Giacobini E; Michel J P
Treatment of Alzheimer's disease. New developments.
Annales de médecine interne 1998;149(4):231-7.
1998: Giacobini E
Cholinergic foundations of Alzheimer's disease therapy.
Journal of physiology, Paris 1998;92(3-4):283-7.
1998: Giacobini E
Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: from tacrine to future applications.
Neurochemistry international 1998;32(5-6):413-9.
1997: Giacobini E
Metrifonate. A viewpoint.
Drugs & aging 1997;11(6):497.
1997: Giacobini E
From molecular structure to Alzheimer therapy.
Japanese journal of pharmacology 1997;74(3):225-41.
1997: Summers K L; Kem W R; Giacobini E
Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex.
Japanese journal of pharmacology 1997;74(2):139-46.
1997: Kalaria R N; Giacobini E
Meeting report: the Fifth International Conference on Alzheimer's Disease and Related Disorders.
Alzheimer disease and associated disorders 1997;11(2):113-9.
1997: Giacobini E; Carpenter J R
Conference report: the Fourth International Nice/Springfield Symposium on Advances in Alzheimer Therapy.
Alzheimer disease and associated disorders 1997;11(1):57-9.
1997: Giacobini E
Alzheimer disease, from molecular biology to therapy.
Advances in experimental medicine and biology 1997;429():235-45.
1996: Summers K L; Lippiello P; Giacobini E
A microdialysis study of the effects of the nicotinic agonist RJR-2403 on cortical release of acetylcholine and biogenic amines.
Neurochemical research 1996;21(10):1181-6.
1996: Giacobini E; Zhu X D; Williams E; Sherman K A
The effect of the selective reversible acetylcholinesterase inhibitor E2020 on extracellular acetylcholine and biogenic amine levels in rat cortex.
Neuropharmacology 1996;35(2):205-11.
1996: Zhu X D; Cuadra G; Brufani M; Maggi T; Pagella P G; Williams E; Giacobini E
Effects of MF-268, a new cholinesterase inhibitor, on acetylcholine and biogenic amines in rat cortex.
Journal of neuroscience research 1996;43(1):120-6.
1996: Giacobini E; Mori F; Lai C C
The effect of cholinesterase inhibitors on the secretion of APPS from rat brain cortex.
Annals of the New York Academy of Sciences 1996;777():393-8.
1996: Giacobini E
New trends in cholinergic therapy for Alzheimer disease: nicotinic agonists or cholinesterase inhibitors?
Progress in brain research 1996;109():311-23.
1995: Cuadra G; Giacobini E
Effects of cholinesterase inhibitors and clonidine coadministration on rat cortex neurotransmitters in vivo.
The Journal of pharmacology and experimental therapeutics 1995;275(1):228-36.
1995: Summers K L; Lippiello P; Verhulst S; Giacobini E
5-fluoronicotine, noranhydroecgonine, and pyridyl-methylpyrrolidine release acetylcholine and biogenic amines in rat cortex in vivo.
Neurochemical research 1995;20(9):1089-94.
1995: Mori F; Cuadra G; Giacobini E
Metrifonate effects on acetylcholine and biogenic amines in rat cortex.
Neurochemical research 1995;20(9):1081-8.
1995: Zhu X D; Giacobini E
Second generation cholinesterase inhibitors: effect of (L)-huperzine-A on cortical biogenic amines.
Journal of neuroscience research 1995;41(6):828-35.
1995: Summers K L; Giacobini E
Effects of local and repeated systemic administration of (-)nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex.
Neurochemical research 1995;20(6):753-9.
1995: Cuadra G; Giacobini E
Coadministration of cholinesterase inhibitors and idazoxan: effects of neurotransmitters in rat cortex in vivo.
The Journal of pharmacology and experimental therapeutics 1995;273(1):230-40.
1995: Zhu X D; Giacobini E; Hornsperger J M
Effect of MDL 73,745 on acetylcholine and biogenic amine levels in rat cortex.
European journal of pharmacology 1995;276(1-2):93-9.
1995: Mori F; Lai C C; Fusi F; Giacobini E
Cholinesterase inhibitors increase secretion of APPs in rat brain cortex.
Neuroreport 1995;6(4):633-6.
1994: Giacobini E
Therapy for Alzheimer's disease. Symptomatic or neuroprotective?
Molecular neurobiology 1994;9(1-3):115-8.
1994: Hornsperger J M; Collard J N; Heydt J G; Giacobini E; Funes S; Dow J; Schirlin D
Trimethylsilylated trifluoromethyl ketones, a novel class of acetylcholinesterase inhibitors: biochemical and pharmacological profile of MDL 73,745.
Biochemical Society transactions 1994;22(3):758-63.
1994: Cuadra G; Summers K; Giacobini E
Cholinesterase inhibitor effects on neurotransmitters in rat cortex in vivo.
The Journal of pharmacology and experimental therapeutics 1994;270(1):277-84.
1994: Giacobini E
Therapy of Alzheimer disease: symptomatic or neuroprotective?
Journal of neural transmission. Supplementum 1994;43():211-7.
1993: Messamore E; Warpman U; Ogane N; Giacobini E
Cholinesterase inhibitor effects on extracellular acetylcholine in rat cortex.
Neuropharmacology 1993;32(8):745-50.
1993: Messamore E; Warpman U; Williams E; Giacobini E
Muscarinic receptors mediate attenuation of extracellular acetylcholine levels in rat cerebral cortex after cholinesterase inhibition.
Neuroscience letters 1993;158(2):205-8.
1993: Messamore E; Ogane N; Giacobini E
Cholinesterase inhibitor effects on extracellular acetylcholine in rat striatum.
Neuropharmacology 1993;32(3):291-6.
1993: Matsuoka Y; Rakonczay Z; Giacobini E; Naritoku D
L-beta-methylamino-alanine-induced behavioral changes in rats.
Pharmacology, biochemistry, and behavior 1993;44(3):727-34.
1993: Giacobini E
Pharmacotherapy of Alzheimer disease: new drugs and novel strategies.
Progress in brain research 1993;98():447-54.
1992: Ogane N; Giacobini E; Struble R
Differential inhibition of acetylcholinesterase molecular forms in normal and Alzheimer disease brain.
Brain research 1992;589(2):307-12.
1992: Ogane N; Giacobini E; Messamore E
Preferential inhibition of acetylcholinesterase molecular forms in rat brain.
Neurochemical research 1992;17(5):489-95.
1992: Linville D G; Giacobini E; Arneric S P
Heptyl-physostigmine enhances basal forebrain control of cortical cerebral blood flow.
Journal of neuroscience research 1992;31(3):573-7.
1992: Giacobini E
Pharmacological replacement of cholinergic function in Alzheimer disease.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():412A-413A.
1991: Schröder H; Giacobini E; Struble R G; Luiten P G; van der Zee E A; Zilles K; Strosberg A D
Muscarinic cholinoceptive neurons in the frontal cortex in Alzheimer's disease.
Brain research bulletin 1991;27(5):631-6.
1991: Schröder H; Giacobini E; Struble R G; Zilles K; Maelicke A
Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease.
Neurobiology of aging 1991;12(3):259-62.
1991: Rakonczay Z; Matsuoka Y; Giacobini E
Effects of L-beta-N-methylamino-L-alanine (L-BMAA) on the cortical cholinergic and glutamatergic systems of the rat.
Journal of neuroscience research 1991;29(1):121-6.
1991: Sugaya K; Downen M; Giacobini E
Nucleus basalis lesions decrease alpha- and kappa-bungarotoxins binding in rat cortex.
Neuroreport 1991;2(4):177-80.
1991: Giacobini E
Nicotinic cholinergic receptors in human brain: effects of aging and Alzheimer.
Advances in experimental medicine and biology 1991;296():303-15.
1991: Schröder H; Giacobini E; Struble R G; Zilles K; Maelicke A; Luiten P G; Strosberg A D
Cellular distribution and expression of cortical acetylcholine receptors in aging and Alzheimer's disease.
Annals of the New York Academy of Sciences 1991;640():189-92.
1990: Giacobini E
Cholinergic receptors in human brain: effects of aging and Alzheimer disease.
Journal of neuroscience research 1990;27(4):548-60.
1990: Sugaya K; Giacobini E; Chiappinelli V A
Nicotinic acetylcholine receptor subtypes in human frontal cortex: changes in Alzheimer's disease.
Journal of neuroscience research 1990;27(3):349-59.
1990: Manyam B V; Giacobini E; Ferraro T N; Hare T A
Cerebrospinal fluid as a reflector of central cholinergic and amino acid neurotransmitter activity in cerebellar ataxia.
Archives of neurology 1990;47(11):1194-9.
1990: Kumar V; Giacobini E
Use of agraphia in subtyping of Alzheimer's disease.
Archives of gerontology and geriatrics 1990;11(2):155-9.
1990: Manyam B V; Giacobini E; Colliver J A
Cerebrospinal fluid acetylcholinesterase and choline measurements in Huntington's disease.
Journal of neurology 1990;237(5):281-4.
1990: Scremin O U; Scremin A M; Somani S M; Giacobini E
Brain regional distribution of physostigmine and its relation to cerebral blood flow following intravenous administration in rats.
Journal of neuroscience research 1990;26(2):188-95.
1990: Manyam B V; Giacobini E; Colliver J A
Cerebrospinal fluid choline levels are decreased in Parkinson's disease.
Annals of neurology 1990;27(6):683-5.
1990: Pomponi M; Giacobini E; Brufani M
Present state and future development of the therapy of Alzheimer disease.
Aging (Milan, Italy) 1990;2(2):125-53.
1990: Giacobini E
The cholinergic system in Alzheimer disease.
Progress in brain research 1990;84():321-32.
1990: Giacobini E
Molecular genetic approaches in the therapy of Alzheimer's disease.
Advances in experimental medicine and biology 1990;265():277-81.
1989: Kumar V; Giacobini E; Markwell S
CSF choline and acetylcholinesterase in early-onset vs. late-onset Alzheimer's disease patients.
Acta neurologica Scandinavica 1989;80(5):461-6.
1989: De Sarno P; Pomponi M; Giacobini E; Tang X C; Williams E
The effect of heptyl-physostigmine, a new cholinesterase inhibitor, on the central cholinergic system of the rat.
Neurochemical research 1989;14(10):971-7.
1989: Tang X C; De Sarno P; Sugaya K; Giacobini E
Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat.
Journal of neuroscience research 1989;24(2):276-85.
1989: Hallak M; Giacobini E
Physostigmine, tacrine and metrifonate: the effect of multiple doses on acetylcholine metabolism in rat brain.
Neuropharmacology 1989;28(3):199-206.
1989: Unni L K; Hannant M E; Becker R E; Giacobini E
Determination of physostigmine in plasma and cerebrospinal fluid by liquid chromatography with electrochemical detection.
Clinical chemistry 1989;35(2):292-5.
1989: De Sarno P; Giacobini E
Modulation of acetylcholine release by nicotinic receptors in the rat brain.
Journal of neuroscience research 1989;22(2):194-200.
1989: Elble R; Giacobini E; Higgins C
Choline levels are increased in cerebrospinal fluid of Alzheimer patients.
Neurobiology of aging 1989;10(1):45-50.
1989: Giacobini E; Becker R
Present progress and future development in the therapy for Alzheimer's disease.
Progress in clinical and biological research 1989;317():1121-54.
1989: Giacobini E; DeSarno P; Clark B; McIlhany M
The cholinergic receptor system of the human brain: neurochemical and pharmacological aspects in aging and Alzheimer.
Progress in brain research 1989;79():335-43.
1988: Kumar V; Smith R C; Sherman K A; Ashford W; Murphy J; Giacobini E; Colliver J
Cortisol responses to cholinergic drugs in Alzheimer's disease.
International journal of clinical pharmacology, therapy, and toxicology 1988;26(10):471-6.
1988: Kumar V; Giacobini E
Cerebrospinal fluid choline, and acetylcholinesterase activity in familial vs. non-familial Alzheimer's disease patients.
Archives of gerontology and geriatrics 1988;7(2):111-7.
1988: Smith R C; Kumar V; Khera G; Elble R; Giacobini E; Colliver J
Brain morphological measures and CSF acetylcholine in Alzheimer dementia.
Psychiatry research 1988;23(1):111-4.
1988: Becker R; Giacobini E; Elble R; McIlhany M; Sherman K
Potential pharmacotherapy of Alzheimer disease. A comparison of various forms of physostigmine administration.
Acta neurologica Scandinavica. Supplementum 1988;116():19-32.
1987: Giacobini E
Modulation of brain acetylcholine levels with cholinesterase inhibitors as a treatment of Alzheimer disease.
The Keio journal of medicine 1987;36(4):381-91.
1987: Di Vona P; Giacobini E; Minucci S
[Obstructive syndrome of the superior vena cava caused by bronchogenic cyst. A clinical case]
Minerva chirurgica 1987;42(17):1335-7.
1987: Giacobini E; Somani S; McIlhany M; Downen M; Hallak M
Pharmacokinetics and pharmacodynamics of physostigmine after intravenous administration in beagle dogs.
Neuropharmacology 1987;26(7B):831-6.
1987: Hallak M; Giacobini E
A comparison of the effects of two inhibitors on brain cholinesterase.
Neuropharmacology 1987;26(6):521-30.
1987: Wortsman J; Foley P J; Tacker W A; Giacobini E; Cryer P E; Frank S
Cerebrospinal fluid changes in experimental cardiac arrest (maximal stress).
The American journal of physiology 1987;252(6 Pt 1):E756-61.
1987: D'Auria S; Minucci S; Giacobini E; Bozzao A; Eleuteri Serpieri D; Petrelli C L; Rossi F; Epifanio A
[Use of computerized tomography as a guide in thoracic needle biopsies]
Archivio Monaldi per le malattie del torace 1987;42(3):219-29.
1987: Elble R; Giacobini E; Scarsella G F
Cholinesterases in cerebrospinal fluid. A longitudinal study in Alzheimer disease.
Archives of neurology 1987;44(4):403-7.
1987: Giacobini E; Mattio T; Mussini I
Aging of cholinergic synapses in the avian iris. Part I--Biochemical studies.
Neurobiology of aging 1987;8(2):123-9.
1987: De Sarno P; Giacobini E; Downen M
Release of acetylcholinesterase from the caudate nucleus of the rat.
Journal of neuroscience research 1987;18(4):578-90.
1987: Giacobini E
Neurochemical analysis of single neurons: a mini-review dedicated to Oliver H. Lowry.
Journal of neuroscience research 1987;18(4):632-7.
1987: Giacobini E
Carbonic anhydrase: the first marker of glial development.
Current topics in developmental biology 1987;21():207-15.
1986: Mattio T; McIlhany M; Giacobini E; Hallak M
The effects of physostigmine on acetylcholinesterase activity of CSF plasma and brain. A comparison of intravenous and intraventricular administration in beagle dogs.
Neuropharmacology 1986;25(10):1167-77.
1986: Hallak M; Giacobini E
Relation of brain regional physostigmine concentration to cholinesterase activity and acetylcholine and choline levels in rat.
Neurochemical research 1986;11(7):1037-48.
1986: Iorio F; Giacobini E; Lorenzon D
Esophageal dischalasia: serendipity during 99mTc thyroid scan.
European journal of nuclear medicine 1986;11(12):505-6.
1986: Kim J S; Gutierrez M C; Giacobini E; Sundberg J P
Experimental maternal hyperpipecolatemia decreases DNA in the mouse brain.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1986;4(2):113-8.
1985: Kim J S; Giacobini E
Transport of pipecolic acid in adult and developing mouse brain.
Neurochemical research 1985;10(10):1405-15.
1985: Kim J S; Giacobini E
Pipecolic acid levels and transport in developing mouse brain.
Brain research 1985;354(2):181-6.
1985: Gutierrez M D; Giacobini E
Identification and characterization of pipecolic acid binding sites in mouse brain.
Neurochemical research 1985;10(5):691-702.
1985: Mattio T G; Richardson J S; Giacobini E
Acute effects of cholinesterase inhibitors on uptake of choline in the rat iris.
Neuropharmacology 1985;24(4):325-8.
1984: Kim J S; Giacobini E
Quantitative determination and regional distribution of pipecolic acid in rodent brain.
Neurochemical research 1984;9(11):1559-69.
1984: Mattio T G; Richardson J S; Giacobini E
Effects of DFP on iridic metabolism and release of acetylcholine and on pupillary function in the rat.
Neuropharmacology 1984;23(10):1207-14.
1984: Richardson J S; Mattio T G; Giacobini E
Amitriptyline and imipramine inhibit the release of acetylcholine from parasympathetic nerve terminals in the rat iris.
Canadian journal of physiology and pharmacology 1984;62(7):857-9.
1983: Ortiz J G; Giacobini E; Schmidt-Glenewinkel T
Allylglycine affects acetylation of putrescine and spermidine in mouse brain.
Neuropharmacology 1983;22(10):1237-9.
1983: Sze P Y; Marchi M; Towle A C; Giacobini E
Increased uptake of [3H]choline by rat superior cervical ganglion: an effect of dexamethasone.
Neuropharmacology 1983;22(6):711-6.
1983: Nishio H; Giacobini E; Ortiz J; Del Carmen Gutierrez M
Accumulation and metabolism of pipecolic acid in the developing brain of the mouse.
Brain research 1983;282(2):107-12.
1983: Ortiz J G; Giacobini E; Schmidt-Glenewinkel T
Acetylation of polyamines in mouse brain: subcellular and regional distribution.
Journal of neuroscience research 1983;9(2):193-201.
1983: Nomura Y; Schmidt-Glenewinkel T; Giacobini E; Ortiz J
Metabolism of cadaverine and pipecolic acid in brain and other organs of the mouse.
Journal of neuroscience research 1983;9(3):279-89.
1982: Hruschak K A; Friedrich V L; Giacobini E
Synaptogenesis in chick paravertebral sympathetic ganglia: a morphometric analysis.
Brain research 1982;256(2):229-40.
1982: Nishio H; Giacobini E; Ortiz J
Accumulation, elimination, release and metabolism of pipecolic acid in the mouse brain following intraventricular injection.
Neurochemical research 1982;7(4):373-85.
1981: Nishio H; Ortiz J; Giacobini E
Accumulation and metabolism of pipecolic acid in the brain and other organs of the mouse.
Neurochemical research 1981;6(12):1241-52.
1981: Yurkewicz L; Lauder J M; Marchi M; Giacobini E
3H-thymidine long survival autoradiography as a method for dating the time of neuronal origin in the chick embryo: the locus coeruleus and cerebellar Purkinje cells.
The Journal of comparative neurology 1981;203(2):257-67.
1981: Nishio H; Giacobini E
Brain uptake of pipecolic acid, amino acids, amines following intracarotid injection in the mouse.
Neurochemical research 1981;6(8):835-45.
1981: Rossi P; Giacobini E; D'Auria S; Tipaldi L; Simonetti G; Passariello R; Linguiti L; Bompiani C
[Abdominal angio-CT: technique of injection and scanning (author's transl)]
La Radiologia medica 1981;67(4):217-23.
1981: Nomura Y; Okuma Y; Segawa T; Schmidt-Glenewinkel T; Giacobini E
Comparison of synaptosomal and glial uptake of pipecolic acid and GABA in rat brain.
Neurochemical research 1981;6(4):391-400.
1981: Marchi M; Hoffman D W; Giacobini E; Volle R
Development and aging of cholinergic synapses. VI. Mechanisms of acetylcholine biosynthesis in the chick iris.
Developmental neuroscience 1981;4(6):442-50.
1981: Marchi M; Yurkewicz L; Giacobini E; Fredrickson T
Development and aging of cholinergic synapses. V. Changes in nicotinic cholinergic receptor binding in ciliary ganglia and irises of the chicken.
Developmental neuroscience 1981;4(4):258-66.
1981: Yurkewicz L; Marchi M; Lauder J M; Giacobini E
Development and aging of noradrenergic cell bodies and axon terminals in the chicken.
Journal of neuroscience research 1981;6(5):621-41.
1980: Nomura Y; Schmidt-Glenewinkel T; Giacobini E
Uptake of piperidine and pipecolic acid by synaptosomes from mouse brain.
Neurochemical research 1980;5(11):1163-73.
1980: Hoffman D W; Giacobini E
Characteristics of norepinephrine uptake in developing peripheral nerve terminals.
Brain research 1980;201(1):57-70.
1980: Marchi M; Hoffman D W; Giacobini E; Fredrickson T
Age dependent changes in choline uptake of the chick iris.
Brain research 1980;195(2):425-31.
1980: Hoffman D W; Salzman S K; Marchi M; Giacobini E
Norepinephrine levels in peripheral nerve terminals during development and aging.
Journal of neurochemistry 1980;34(6):1785-7.
1980: Marchi M; Hoffman D W; Giacobini E; Fredrickson T
Development and aging of cholinergic synapses. IV. Acetylcholinesterase and choline acetyltransferase activities in autonomic ganglia and iris of the chick.
Developmental neuroscience 1980;3(4-6):235-47.
1980: Marchi M; Hoffman D W; Mussini I; Giacobini E
Development and aging of cholinergic synapses. III. Choline uptake in the developing iris of the chick.
Developmental neuroscience 1980;3(4-6):185-98.
1980: Marchi M; Giacobini E
Development and aging of cholinergic synapses. II. Continuous growth of acetylcholine and choline levels in autonomic ganglia and iris of the chick.
Developmental neuroscience 1980;3(1):39-48.
1980: Giacobini E; Nomura Y; Schmidt-Glenewinkel T
Pipecolic acid: origin, biosynthesis and metabolism in the brain.
Cellular and molecular biology, including cyto-enzymology 1980;26(2):135-46.
1980: Hoffman D W; Marchi M; Giacobini E
Norepinephrine uptake in aging adrenergic nerve terminals.
Neurobiology of aging 1980;1(1):65-8.
1980: Dahl A L; Giacobini E; Serra G; Manara L
The fate of tritium-labeled reserpine in the chick embryo: a preliminary report.
Journal of neuroscience research 1980;5(1):73-8.
1979: Giacobini E; Pilar G; Suszkiw J; Uchimura H
Normal distribution and denervation changes of neurotransmitter related enzymes in cholinergic neurones.
The Journal of physiology 1979;286():233-53.
1979: Marchi M; Giacobini E; Hruschak K
Development and aging of cholinergic synapses. I. Endogenous levels of acetylcholine and choline in developing autonomic ganglia and iris of the chick.
Developmental neuroscience 1979;2(5):201-12.
1979: Giacobini E
Cholinergic receptors in synaptogenesis: drug-receptor interaction during development.
Proceedings of the Western Pharmacology Society 1979;22():15-9.
1979: Scarsella G; Toschi G; Bareggi S R; Giacobini E
Molecular forms of cholinesterases in cerebrospinal fluid, blood plasma, and brain tissue of the beagle dog.
Journal of neuroscience research 1979;4(1):19-24.
1978: Chiappinelli V A; Giacobini E
Time course of appearance of alpha-bungarotoxin binding sites during development of chick ciliary ganglion and iris.
Neurochemical research 1978;3(4):465-78.
1978: Scarsella G; Toschi G; Chiappinelli V A; Giacobini E
Molecular forms of acetylcholinesterase in the ciliary ganglion and iris of the chick. Developmental changes and effects of axotomy.
Developmental neuroscience 1978;1(3-4):133-41.
1978: Bareggi S R; Giacobini E
Acetylcholinesterase activity in ventricular and cisternal CSF of dogs: effect of chlorpromazine.
Journal of neuroscience research 1978;3(5-6):335-9.
1977: Fairman K; Chiappinelli V; Giacobini E; Yurkewicz L
The effect of a single dose of reserpine administered prior to incubation on the development of tyrosine hydroxylase activity in chick sympathetic ganglia.
Brain research 1977;122(3):503-12.
1976: Chiappinelli V; Giacobini E; Pilar G; Uchimura H
Induction of cholinergic enzymes in chick ciliary ganglion and iris muscle cells during synapse formation.
The Journal of physiology 1976;257(3):749-66.
1976: Fairman K; Giacobini E; Chiappinelli V
Developmental variations of tyrosine hydroxylase and acetylcholinesterase in embryonic and post-hatching chicken sympathetic ganglia.
Brain research 1976;102(2):301-12.
1976: Giacobini E
Piperidine: a new neuromodulator or a hypogenic substance?
Advances in biochemical psychopharmacology 1976;15():17-56.
1976: Giacobini E
New first messengers in a pluralistic society of neurotransmitters.
Advances in biochemical psychopharmacology 1976;15():1-4.
1975: Drucker-Colín R R; Giacobini E
Sleep-inducing effect of piperidine.
Brain research 1975;88(1):186-9.
1975: Castrucci A; De Medici L; Giacobini E; Valenti M
[Panangiographic and hemodynamic study of portal hypertension. Clinical and therapeutic considerations]
Journal de radiologie, d'électrologie, et de médecine nucléaire 1975;56 suppl 2():531-2.
1975: Giacobini E
Neuronal control of neurotransmitters biosynthesis during development.
Journal of neuroscience research 1975;1(3-4):315-31.
1975: Giacobini E
The use of microchemical techniques for the identification of new transmitter molecules in neurons.
Journal of neuroscience research 1975;1(1):1-18.
1974: Dolezalova H; Giacobini E; Giacobini G; Rossi A; Toschi G
Developmental variations of choline acetyl-transferase, dopamine-beta-hydroxylase and monoamineoxidase in chicken embryo and chicken sympathetic ganglia.
Brain research 1974;73(2):309-20.
1973: Stepita-Klauco M; Dolezalova H; Giacobini E
The action of piperidine on cholinoceptive neurons of the snail.
Brain research 1973;63():141-52.
1973: Dolezalova H; Stepita-Klauco M; Giacobini E
The passage of tritiated piperidine into the central ganglia and other tissues of the snail.
The International journal of neuroscience 1973;6(2):89-95.
1973: Dolezalova H; Giacobini E; Seiler N; Schneider H H
Determination of piperidine in snail brain (Helix pomatia).
Brain research 1973;55(1):242-4.
1973: Hemminki K; Hemminki E; Giacobini E
Activity of enzymes related to neurotransmission in neuronal and glial fractions.
The International journal of neuroscience 1973;5(2):87-90.
1973: Dolezalova H; Giacobini E; Stepita-Klauco M
An attempt to identify putative neurotransmitter molecules in the central nervous system of the snail.
The International journal of neuroscience 1973;5(2):53-6.
1972: Koslow S H; Giacobini E; Kerpel-Fronius S; Olson L
Cholinergic transmission in the hypoglossal reinnervated nictitating membrane of the cat: an enzymatic, histochemical and physiological study.
The Journal of pharmacology and experimental therapeutics 1972;180(3):664-71.
1971: Giacobini E
[Biochemical psychotherories. Where do we stand in 1971? 1. Monoamine theories]
Läkartidningen 1971;68(49):5699-712.
1971: Filogamo G; Giacobini E; Giacobini G; Noré B
Developmental changes of DOPA decarboxylase in chick embryo and chick spinal and sympathetic ganglia.
Journal of neurochemistry 1971;18(8):1589-91.
1971: Koslow S H; Stepita-Klauco M; Olson L; Giacobini E
Functional reinnervation of cat sympathetic ganglia with splenic nerve homografts.
Experientia 1971;27(7):799-801.
1971: Giacobini E; Noré B
Dopa-decarboxylase in autonomic and sensory ganglia of the cat.
Acta physiologica Scandinavica 1971;82(2):209-17.
1971: Giacobini E
Biochemistry of synaptic plasticity studied in single neurons.
Advances in cytopharmacology 1971;1():427-31.
1971: Giacobini E; Hökfelt T; Kerpel-Fronius S; Koslow S H; Mitchard M; Noré B
Micro-scale procedure for the preparation of subcellular fractions from individual autonomic ganglia.
Journal of neurochemistry 1971;18(2):223-31.
1971: Giacobini E; Przybylski A
Studies on hypoxia in isolated neurons. II. The effect of hypoxia on the impulse activity and the intracellular K-Na ratio of the slowly adapting stretch receptor neuron (SRN).
The International journal of neuroscience 1971;1(3):163-9.
1971: Giacobini E; Przybylski A
Studies on hypoxia in isolated neurons. I. An open chamber apparatus for studying the effect of hypoxia on isolated neuron preparations.
The International journal of neuroscience 1971;1(3):159-62.
1970: Mitchard M; Giacobini E; Carlsson B
A sensitive, automated magnetic diver balance.
Analytical biochemistry 1970;37(1):112-24.
1970: Giacobini G; Marchisio P C; Giacobini E; Koslow S H
Developmental changes of cholinesterases and monoamine oxidase in chick embryo spinal and sympathetic ganglia.
Journal of neurochemistry 1970;17(8):1177-85.
1970: Giacobini E; Kerpel-Fronius S
Histochemical and biochemical correlations of monoamine oxidase activity in autonomic and sensory ganglia of the cat.
Acta physiologica Scandinavica 1970;78(4):522-8.
1970: Giacobini E; Karjalainen K; Kerpel-Fronius S; Ritzén M
Monoamines and monoamine oxidase in denervated sympathetic ganglia of the cat.
Neuropharmacology 1970;9(1):59-66.
1970: Giacobini E
Biochemistry of synaptic plasticity studied in single neurons.
Advances in biochemical psychopharmacology 1970;2():9-64.
1969: Koslow S H; Giacobini E
An isotopic micromethod for the measurement of cholinesterase activity in individual cells.
Journal of neurochemistry 1969;16(11):1523-8.
1969: Giacobini E; Kerpel-Fronius S
Catechol-O-methyltransferase in autonomic and sensory ganglia of the cat.
Acta physiologica Scandinavica 1969;75(4):523-9.
1969: Giacobini E
Value and limitations of quantitative chemical studies in individual cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1969;17(3):139-55.
1969: Giacobini E; Mitchard M
A micro-scale procedure for the preparation of synaptosomal and mitochondrial fractions from cervical sympathetic ganglia and caudate nuclei in the cat.
British journal of pharmacology 1969;35(2):370P.
1969: Giacobini E
Chemical studies on individual neurons. II. Invertebrate nerve cells.
Neurosciences research 1969;2(0):111-202.
1968: Consolo S; Giacobini E; Karjalainen K
Monoamine oxidase in sympathetic ganglia of the cat.
Acta physiologica Scandinavica 1968;74(4):513-20.
1968: Giacobini E; Jongkind J F
Pentose shunt enzymes in the crustacean stretch receptor neuron after impulse activity.
Acta physiologica Scandinavica 1968;73(1):255-6.
1968: Giacobini E
Biochemistry and pharmacology of autonomic neurons.
Annali dell'Istituto superiore di sanità 1968;4(5):459-88.
1967: Giacobini E; Hovmark S; Kometiani Z
Intracellular variations of Na and K in isolated nerve cells.
Acta physiologica Scandinavica 1967;71(4):391-400.
1967: Carlsson B; Giacobini E; Hovmark S
An instrument for simultaneous determination of sodium and potassium in microsamples of biological material.
Acta physiologica Scandinavica 1967;71(4):379-90.
1967: Buckley G; Consolo S; Giacobini E; Sjöqvist F
Cholinacetylase in innervated and denervated sympathetic ganglia and ganglion cells of the cat.
Acta physiologica Scandinavica 1967;71(4):348-56.
1967: Buckley G; Consolo S; Giacobini E; McCaman R
A micromethod for the determination of choline acetylase in individual cells.
Acta physiologica Scandinavica 1967;71(4):341-7.
1967: Giacobini E; Palmborg B; Sjöqvist F
Cholinesterase activity in innervated and denervated sympathetic ganglion cells of the cat.
Acta physiologica Scandinavica 1967;69(4):355-61.
1967: Giacobini E
Energy metabolism and ion transport studied in single neurons.
Protoplasma 1967;63(1):52-5.
1966: Giacobini E; Grasso A
Variations of glycolytic intermediates, phosphate compounds and pyridine nucleotides after prolonged stimulation of an isolated crustacean neurone.
Acta physiologica Scandinavica 1966;66(1):49-57.
1962: GIACOBINI E
Use of microgasometric techniques in pharmacological studies.
Biochemical pharmacology 1962;9():155-64.
1962: GIACOBINI E
A cytochemical study of the localization of carbonic anhydrase in the nervous system.
Journal of neurochemistry 1962;9():169-77.
1961: GIACOBINI E
Localization of carbonic anhydrase in the nervous system.
Science (New York, N.Y.) 1961;134():1524-5.
1960: GIACOBINI E
The intracellular localization of cholinesterase.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1960;8():419-24.
1960: GIACOBINI E; IZIKOWITZ S; WEGMANN A
The urinary excretion of noradrenaline and adrenaline during acute alcohol intoxication in alcoholic addicts.
Experientia 1960;16():467.
1959: GIACOBINI E
Quantitative determination of cholinesterase in individual spinal ganglion cells.
Acta physiologica Scandinavica 1959;45():238-54.
1957: GIACOBINI E
Quantitative determination of cholinesterase in individual sympathetic cells.
Journal of neurochemistry 1957;1(3):234-44.
1956: GIACOBINI E
Histochemical demonstration of AChE activity in isolated nerve cells.
Acta physiologica Scandinavica 1956;36(3):276-90.
1956: GIACOBINI E; ZAJICEK J
Quantitative determination of acetylcholinesterase activity in individual nerve cells.
Nature 1956;177(4500):185-6.

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