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John Giddings

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Keiji Nogami; Evgueni L Saenko; Masahiro Takeyama; John C Giddings; Akira Yoshioka; Midori Shima
Identification of a thrombin-interactive site within the FVIII A2 domain that is responsible for the cleavage at Arg372.
Keiji Nogami; Midori Shima; John C Giddings; Masahiro Takeyama; Ichiro Tanaka; Akira Yoshioka
Relationship between the binding sites for von Willebrand factor, phospholipid, and human factor VIII C2 inhibitor alloantibodies within the factor VIII C2 domain.
Masahiro Takeyama; Yoshihiko Sakurai; Midori Shima; Tomoko Matsumoto; Keiji Nogami; Ichiro Tanaka; Tomohiro Takeda; John C Giddings; Akira Yoshioka
Heparin-induced inhibitory effects of a prothrombin complex concentrate on global tests of haemostasis.

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2008: Keiji Nogami; Evgueni L Saenko; Masahiro Takeyama; John C Giddings; Akira Yoshioka; Midori Shima
Identification of a thrombin-interactive site within the FVIII A2 domain that is responsible for the cleavage at Arg372.
British journal of haematology 2008;140(4):433-43.
2007: Keiji Nogami; Midori Shima; John C Giddings; Masahiro Takeyama; Ichiro Tanaka; Akira Yoshioka
Relationship between the binding sites for von Willebrand factor, phospholipid, and human factor VIII C2 inhibitor alloantibodies within the factor VIII C2 domain.
International journal of hematology 2007;85(4):317-22.
2007: Masahiro Takeyama; Yoshihiko Sakurai; Midori Shima; Tomoko Matsumoto; Keiji Nogami; Ichiro Tanaka; Tomohiro Takeda; John C Giddings; Akira Yoshioka
Heparin-induced inhibitory effects of a prothrombin complex concentrate on global tests of haemostasis.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2007;18(1):1-7.
2006: T Inoue; Midori Shima; Masahiro Takeyama; Tomoko Matsumoto; Katsumi Nishiya; Ichiro Tanaka; Yoshihiko Sakurai; John C Giddings; Akira Yoshioka
Higher recovery of factor VIII (FVIII) with intermediate FVIII/von Willebrand factor concentrate than with recombinant FVIII in a haemophilia A patient with an inhibitor.
Haemophilia : the official journal of the World Federation of Hemophilia 2006;12(1):110-3.
2004: T Hayashi; Ichiro Tanaka; Midori Shima; Koichi Yoshida; Kazuyoshi Fukuda; Yoshihiko Sakurai; Tomoko Matsumoto; John C Giddings; Akira Yoshioka
Unresponsiveness to factor VIII inhibitor bypassing agents during haemostatic treatment for life-threatening massive bleeding in a patient with haemophilia A and a high responding inhibitor.
Haemophilia : the official journal of the World Federation of Hemophilia 2004;10(4):397-400.
2004: Yukiko Hayashi; Midori Shima; Hiromichi Kanehiro; Yousuke Nakajima; Natsuko Daikoku; Masanori Higuchi; Sachiko Miyagawa; Seiki Kamisue; Kazuyoshi Fukuda; Ichiro Tanaka; John C Giddings; Akira Yoshioka
Ecthyma gangrenosum combined with multiple perforations of the small intestine associated with Pseudomonas aeruginosa.
Pediatrics international : official journal of the Japan Pediatric Society 2004;46(1):104-8.
2004: Yoshihiko Sakurai; Midori Shima; John C Giddings; Masahiro Takeyama; Shogo Kasuda; Keiji Nogami; Katsumi Nishiya; Akira Yoshioka
A critical role for thrombin in platelet aggregation under high shear stress.
Thrombosis research 2004;113(5):311-8.
2003: M Shibata; Midori Shima; H Misu; Y Okimoto; John C Giddings; Akira Yoshioka
Management of haemophilia B inhibitor patients with anaphylactic reactions to FIX concentrates.
Haemophilia : the official journal of the World Federation of Hemophilia 2003;9(3):269-71.
2002: Keiji Nogami; Midori Shima; Katsumi Nishiya; Yoshihiko Sakurai; Ichiro Tanaka; John C Giddings; Evgueni L Saenko; Akira Yoshioka
Human factor VIII inhibitor alloantibodies with a C2 epitope inhibit factor Xa-catalyzed factor VIII activation: a new anti-factor VIII inhibitory mechanism.
Thrombosis and haemostasis 2002;87(3):459-65.
2002: Keiji Nogami; Midori Shima; Katsumi Nishiya; Kazuya Hosokawa; Evgueni L Saenko; John C Giddings; Ichiro Tanaka; Akira Yoshioka
Anticoagulant effects of a synthetic peptide containing residues Thr-2253-Gln-2270 within factor VIII C2 domain that selectively inhibits factor Xa-catalysed factor VIII activation.
British journal of haematology 2002;116(4):868-74.
2001: Tomoko Matsumoto; Midori Shima; Kazuyoshi Fukuda; Keiji Nogami; John C Giddings; T Murakami; Ichiro Tanaka; Akira Yoshioka
Immunological characterization of factor VIII autoantibodies in patients with acquired hemophilia A in the presence or absence of underlying disease.
Thrombosis research 2001;104(6):381-8.
2001: Keiji Nogami; Midori Shima; John C Giddings; Kazuya Hosokawa; M Nagata; Seiki Kamisue; Hiroshi Suzuki; Masaru Shibata; Evgueni L Saenko; Ichiro Tanaka; Akira Yoshioka
Circulating factor VIII immune complexes in patients with type 2 acquired hemophilia A and protection from activated protein C-mediated proteolysis.
Blood 2001;97(3):669-77.
1999: Keiji Nogami; Midori Shima; H Nakai; Ichiro Tanaka; Hiroshi Suzuki; Shogo Morichika; Masaru Shibata; Evgueni L Saenko; Dorothea Scandella; John C Giddings; Akira Yoshioka
Identification of a factor VIII peptide, residues 2315-2330, which neutralizes human factor VIII C2 inhibitor alloantibodies: requirement of Cys2326 and Glu2327 for maximum effect.
British journal of haematology 1999;107(1):196-203.
1999: Masaru Shibata; Midori Shima; Yoshihiro Fujimura; Y Takahashi; H Nakai; Yoshihiko Sakurai; M Asatani; A Nomura; H Take; John C Giddings; Akira Yoshioka
Identification of the binding site for an alloantibody to von Willebrand factor which inhibits binding to glycoprotein Ib within the amino-terminal region flanking the A1 domain.
Thrombosis and haemostasis 1999;81(5):793-8.
1999: H Matsui; M Sugimoto; S Tsuji; Midori Shima; John C Giddings; Akira Yoshioka
Transient hypoplastic anemia caused by primary human parvovirus B19 infection in a previously untreated patient with hemophilia transfused with a plasma-derived, monoclonal antibody-purified factor VIII concentrate.
Journal of pediatric hematology/oncology 1999;21(1):74-6.
1998: Hiroshi Suzuki; Midori Shima; Seiki Kamisue; H Nakai; Keiji Nogami; Masaru Shibata; Shogo Morichika; Ichiro Tanaka; John C Giddings; Akira Yoshioka
The role of platelet von Willebrand factor in the binding of factor VIII to activated platelets.
Thrombosis research 1998;90(5):207-14.
1997: Midori Shima; I Tanaka; Y Sawamoto; H Kanehiro; N Matsuo; A Nishimura; John C Giddings; Akira Yoshioka
Successful treatment of two brothers with congenital afibrinogenemia for splenic rupture using heat- and solvent detergent-treated fibrinogen concentrates.
Journal of pediatric hematology/oncology 1997;19(5):462-5.
1996: Y Sawamoto; M Shima; M Yamamoto; Seiki Kamisue; H Nakai; Ichiro Tanaka; K Hayashi; John C Giddings; Akira Yoshioka
Measurement of anti-factor IX IgG subclasses in haemophilia B patients who developed inhibitors with episodes of allergic reactions to factor IX concentrates.
Thrombosis research 1996;83(4):279-86.