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A L J Gielkens

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Anneke Feberwee; Wil Landman; Th von Banniseht-Wysmuller; Don Klinkenberg; J C M Vernooij; A L J Gielkens; Arjan Stegeman
The effect of a live vaccine on the horizontal transmission of Mycoplasma gallisepticum.
Anneke Feberwee; Th von Banniseht-Wysmuller; J C M Vernooij; A L J Gielkens; Arjan Stegeman
The effect of vaccination with a bacterin on the horizontal transmission of Mycoplasma gallisepticum.
Anneke Feberwee; Jeroen R Dijkstra; Th von Banniseht-Wysmuller; A L J Gielkens; Jaap A Wagenaar
Genotyping of Mycoplasma gallisepticum and M. synoviae by Amplified Fragment Length Polymorphism (AFLP) analysis and digitalized Random Amplified Polymorphic DNA (RAPD) analysis.

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2006: Anneke Feberwee; Wil Landman; Th von Banniseht-Wysmuller; Don Klinkenberg; J C M Vernooij; A L J Gielkens; Arjan Stegeman
The effect of a live vaccine on the horizontal transmission of Mycoplasma gallisepticum.
Avian pathology : journal of the W.V.P.A 2006;35(5):359-66.
2006: Anneke Feberwee; Th von Banniseht-Wysmuller; J C M Vernooij; A L J Gielkens; Arjan Stegeman
The effect of vaccination with a bacterin on the horizontal transmission of Mycoplasma gallisepticum.
Avian pathology : journal of the W.V.P.A 2006;35(1):35-7.
2005: Anneke Feberwee; Jeroen R Dijkstra; Th von Banniseht-Wysmuller; A L J Gielkens; Jaap A Wagenaar
Genotyping of Mycoplasma gallisepticum and M. synoviae by Amplified Fragment Length Polymorphism (AFLP) analysis and digitalized Random Amplified Polymorphic DNA (RAPD) analysis.
Veterinary microbiology 2005;111(1-2):125-31.
2005: Anneke Feberwee; DR Mekkes; Don Klinkenberg; J C M Vernooij; A L J Gielkens; Arjan Stegeman
An experimental model to quantify horizontal transmission of Mycoplasma gallisepticum.
Avian pathology : journal of the W.V.P.A 2005;34(4):355-61.
2005: Hein J Boot; Arjan J W Hoekman; A L J Gielkens
The enhanced virulence of very virulent infectious bursal disease virus is partly determined by its B-segment.
Archives of virology 2005;150(1):137-44.
2003: SO Al-Garib; A L J Gielkens; Erik Gruys; Ben P H Peeters; Guus Koch
Tissue tropism in the chicken embryo of non-virulent and virulent Newcastle diseases strains that express green fluorescence protein.
Avian pathology : journal of the W.V.P.A 2003;32(6):591-6.
2003: SO Al-Garib; Erik Gruys; A L J Gielkens; Guus Koch
Detection of antibody-forming cells directed against Newcastle disease virus and their immunoglobulin class by double immunoenzyme histochemistry.
Avian diseases 2003;47(2):453-7.
2003: Arie Kant; Francis Balk; Leontine Born; Dirk van Roozelaar; Jos Heijmans; A L J Gielkens; A A H M ter Huurne
Classification of Dutch and German avian reoviruses by sequencing the sigma C protein.
Veterinary research 2003;34(2):203-12.
2003: SO Al-Garib; A L J Gielkens; D E Gruys; L Hartog; Guus Koch
Immunoglobulin class distribution of systemic and mucosal antibody responses to Newcastle disease in chickens.
Avian diseases 2003;47(1):32-40.
2002: Hein J Boot; A A H M ter Huurne; Arjan J W Hoekman; J M A Pol; A L J Gielkens; Ben P H Peeters
Exchange of the C-terminal part of VP3 from very virulent infectious bursal disease virus results in an attenuated virus with a unique antigenic structure.
Journal of virology 2002;76(20):10346-55.
2001: Hein J Boot; A A H M ter Huurne; S A Vastenhouw; A Kant; Ben P H Peeters; A L J Gielkens
Rescue of infectious bursal disease virus from mosaic full-length clones composed of serotype I and II cDNA.
Archives of virology 2001;146(10):1991-2007.
2001: J H Ovelgönne; Wil Landman; Erik Gruys; A L J Gielkens; B P Peeters
Identical amyloid precursor proteins in two breeds of chickens which differ in susceptibility to develop amyloid arthropathy.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2001;8(1):41-51.
2001: Ben P H Peeters; Olav S de Leeuw; I Verstegen; Guus Koch; A L J Gielkens
Generation of a recombinant chimeric Newcastle disease virus vaccine that allows serological differentiation between vaccinated and infected animals.
Vaccine 2001;19(13-14):1616-27.
2000: Hein J Boot; A A H M ter Huurne; Arjan J W Hoekman; Ben P H Peeters; A L J Gielkens
Rescue of very virulent and mosaic infectious bursal disease virus from cloned cDNA: VP2 is not the sole determinant of the very virulent phenotype.
Journal of virology 2000;74(15):6701-11.
2000: Ben P H Peeters; Y K Gruijthuijsen; Olav S de Leeuw; A L J Gielkens
Genome replication of Newcastle disease virus: involvement of the rule-of-six.
Archives of virology 2000;145(9):1829-45.
2000: Mirriam G J Tacken; Peter J M Rottier; A L J Gielkens; Ben P H Peeters
Interactions in vivo between the proteins of infectious bursal disease virus: capsid protein VP3 interacts with the RNA-dependent RNA polymerase, VP1.
The Journal of general virology 2000;81(Pt 1):209-18.
1999: Hein J Boot; A A H M ter Huurne; Ben P H Peeters; A L J Gielkens
Efficient rescue of infectious bursal disease virus from cloned cDNA: evidence for involvement of the 3'-terminal sequence in genome replication.
Virology 1999;265(2):330-41.
1999: Ben P H Peeters; Olav S de Leeuw; Guus Koch; A L J Gielkens
Rescue of Newcastle disease virus from cloned cDNA: evidence that cleavability of the fusion protein is a major determinant for virulence.
Journal of virology 1999;73(6):5001-9.
1996: B J Hooft van Iddekinge; Niels De Wind; G Wensvoort; Tjeerd G Kimman; A L J Gielkens; R J M Moormann
Comparison of the protective efficacy of recombinant pseudorabies viruses against pseudorabies and classical swine fever in pigs; influence of different promoters on gene expression and on protection.
Vaccine 1996;14(1):6-12.
1996: MJ Kaashoek; F A van Engelenburg; A Moerman; A L J Gielkens; F A M Rijsewijk; JT van Oirschot
Virulence and immunogenicity in calves of thymidine kinase- and glycoprotein E-negative bovine herpesvirus 1 mutants.
Veterinary microbiology 1996;48(1-2):143-53.
1995: JT van Oirschot; F A M Rijsewijk; P J Straver; R C Ruuls; J Quak; A Davidse; F Westenbrink; A L J Gielkens; J E van Dijk; A Moerman
Virulence and genotype of a bovine herpesvirus 1 isolate from semen of a subclinically infected bull.
The Veterinary record 1995;137(10):235-9.
1995: F Wagenaar; J M A Pol; B Peeters; A L J Gielkens; Niels De Wind; Tjeerd G Kimman
The US3-encoded protein kinase from pseudorabies virus affects egress of virions from the nucleus.
The Journal of general virology 1995;76 ( Pt 7)():1851-9.
1995: P B Belt; I H Muileman; Bram Schreuder; J Bos-de Ruijter; A L J Gielkens; Mari A Smits
Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie.
The Journal of general virology 1995;76 ( Pt 3)():509-17.
1995: R Jansen; J Briaire; Elbarte M Kamp; A L J Gielkens; Mari A Smits
The CAMP effect of Actinobacillus pleuropneumoniae is caused by Apx toxins.
FEMS microbiology letters 1995;126(2):139-43.
1995: Hilde E Smith; Henk J Wisselink; U Vecht; A L J Gielkens; Mari A Smits
High-efficiency transformation and gene inactivation in Streptococcus suis type 2.
Microbiology (Reading, England) 1995;141 ( Pt 1)():181-8.
1995: R Jansen; J Briaire; Hilde E Smith; P Dom; Freddy Haesebrouck; Elbarte M Kamp; A L J Gielkens; Mari A Smits
Knockout mutants of Actinobacillus pleuropneumoniae serotype 1 that are devoid of RTX toxins do not activate or kill porcine neutrophils.
Infection and immunity 1995;63(1):27-37.
1995: Tjeerd G Kimman; A L J Gielkens; K Glazenburg; L Jacobs; Mart de Jong; W A Mulder; Ben P H Peeters
Characterization of live pseudorabies virus vaccines.
Developments in biological standardization 1995;84():89-96.
1995: K L Glazenburg; R J M Moormann; Tjeerd G Kimman; A L J Gielkens; Ben P H Peeters
Genetic recombination of pseudorabies virus: evidence that homologous recombination between insert sequences is less frequent than between autologous sequences.
Archives of virology 1995;140(4):671-85.
1995: K L Glazenburg; Ben P H Peeters; J M A Pol; A L J Gielkens; R J M Moormann
Construction and properties of pseudorabies virus recombinants with altered control of immediate-early gene expression.
Journal of virology 1995;69(1):189-97.
1994: K L Glazenburg; R J M Moormann; Tjeerd G Kimman; A L J Gielkens; Ben P H Peeters
In vivo recombination of pseudorabies virus strains in mice.
Virus research 1994;34(2):115-26.
1994: R Jansen; J Briaire; A B van Geel; Elbarte M Kamp; A L J Gielkens; Mari A Smits
Genetic map of the Actinobacillus pleuropneumoniae RTX-toxin (Apx) operons: characterization of the ApxIII operons.
Infection and immunity 1994;62(10):4411-8.
1994: F A van Engelenburg; MJ Kaashoek; F A M Rijsewijk; L van den Burg; A Moerman; A L J Gielkens; JT van Oirschot
A glycoprotein E deletion mutant of bovine herpesvirus 1 is avirulent in calves.
The Journal of general virology 1994;75 ( Pt 9)():2311-8.
1994: K L Glazenburg; M Elgersma-Hooisma; J Briaire; J Voermans; Tjeerd G Kimman; A L J Gielkens; R J M Moormann
Vaccine properties of pseudorabies virus strain 783 are not affected by a deletion of 71 base pairs in the promoter/enhancer region of the viral immediate early gene.
Vaccine 1994;12(12):1097-100.
1994: Niels De Wind; Ben P H Peeters; A Zuderveld; A L J Gielkens; A J Berns; Tjeerd G Kimman
Mutagenesis and characterization of a 41-kilobase-pair region of the pseudorabies virus genome: transcription map, search for virulence genes, and comparison with homologs of herpes simplex virus type 1.
Virology 1994;200(2):784-90.
1994: MJ Kaashoek; A Moerman; J Madić; F A M Rijsewijk; J Quak; A L J Gielkens; JT van Oirschot
A conventionally attenuated glycoprotein E-negative strain of bovine herpesvirus type 1 is an efficacious and safe vaccine.
Vaccine 1994;12(5):439-44.
1994: B Peeters; A Bouma; T de Bruin; R J M Moormann; A L J Gielkens; Tjeerd G Kimman
Non-transmissible pseudorabies virus gp50 mutants: a new generation of safe live vaccines.
Vaccine 1994;12(4):375-80.
1994: W A Mulder; J Priem; K L Glazenburg; F Wagenaar; E Gruys; A L J Gielkens; J M A Pol; Tjeerd G Kimman
Virulence and pathogenesis of non-virulent and virulent strains of pseudorabies virus expressing envelope glycoprotein E1 of hog cholera virus.
The Journal of general virology 1994;75 ( Pt 1)():117-24.
1994: A L J Gielkens; Ben P H Peeters
Function of Aujeszky's disease virus proteins in virus replication and virulence.
Acta veterinaria Hungarica 1994;42(2-3):227-41.
1993: L Jacobs; W A Mulder; JT van Oirschot; A L J Gielkens; Tjeerd G Kimman
Deleting two amino acids in glycoprotein gI of pseudorabies virus decreases virulence and neurotropism for pigs, but does not affect immunogenicity.
The Journal of general virology 1993;74 ( Pt 10)():2201-6.
1993: R Jansen; J Briaire; Elbarte M Kamp; A L J Gielkens; Mari A Smits
Structural analysis of the Actinobacillus pleuropneumoniae-RTX-toxin I (ApxI) operon.
Infection and immunity 1993;61(9):3688-95.
1993: Hilde E Smith; F H Reek; U Vecht; A L J Gielkens; Mari A Smits
Repeats in an extracellular protein of weakly pathogenic strains of Streptococcus suis type 2 are absent in pathogenic strains.
Infection and immunity 1993;61(8):3318-26.
1993: R Jansen; J Briaire; Elbarte M Kamp; A L J Gielkens; Mari A Smits
Cloning and characterization of the Actinobacillus pleuropneumoniae-RTX-toxin III (ApxIII) gene.
Infection and immunity 1993;61(3):947-54.
1993: Niels De Wind; Anton Berns; A L J Gielkens; Tjeerd G Kimman
Ribonucleotide reductase-deficient mutants of pseudorabies virus are avirulent for pigs and induce partial protective immunity.
The Journal of general virology 1993;74 ( Pt 3)():351-9.
1993: L Jacobs; H J Rziha; Tjeerd G Kimman; A L J Gielkens; JT van Oirschot
Deleting valine-125 and cysteine-126 in glycoprotein gI of pseudorabies virus strain NIA-3 decreases plaque size and reduces virulence in mice.
Archives of virology 1993;131(3-4):251-64.
1993: B Peeters; J M A Pol; A L J Gielkens; R J M Moormann
Envelope glycoprotein gp50 of pseudorabies virus is essential for virus entry but is not required for viral spread in mice.
Journal of virology 1993;67(1):170-7.
1992: Tjeerd G Kimman; J M A Pol; Niels De Wind; N Oei-Lie; A J Berns; A L J Gielkens
Role of different genes in the virulence and pathogenesis of Aujeszky's disease virus.
Veterinary microbiology 1992;33(1-4):45-52.
1992: K Glazenburg; A L J Gielkens; R J M Moormann
Effects of replacing the promoter of the immediate early gene with the promoter of Drosophila heat-shock gene HSP70 on the growth and virulence of pseudorabies virus.
Veterinary microbiology 1992;33(1-4):35-43.
1992: Hilde E Smith; U Vecht; A L J Gielkens; Mari A Smits
Cloning and nucleotide sequence of the gene encoding the 136-kilodalton surface protein (muramidase-released protein) of Streptococcus suis type 2.
Infection and immunity 1992;60(6):2361-7.
1992: B Peeters; Niels De Wind; R Broer; A L J Gielkens; R J M Moormann
Glycoprotein H of pseudorabies virus is essential for entry and cell-to-cell spread of the virus.
Journal of virology 1992;66(6):3888-92.
1992: Tjeerd G Kimman; Niels De Wind; N Oei-Lie; J M A Pol; A J Berns; A L J Gielkens
Contribution of single genes within the unique short region of Aujeszky's disease virus (suid herpesvirus type 1) to virulence, pathogenesis and immunogenicity.
The Journal of general virology 1992;73 ( Pt 2)():243-51.
1992: B Peeters; Niels De Wind; M Hooisma; F Wagenaar; A L J Gielkens; R J M Moormann
Pseudorabies virus envelope glycoproteins gp50 and gII are essential for virus penetration, but only gII is involved in membrane fusion.
Journal of virology 1992;66(2):894-905.
1991: Mari A Smits; J Briaire; R Jansen; Hilde E Smith; Elbarte M Kamp; A L J Gielkens
Cytolysins of Actinobacillus pleuropneumoniae serotype 9.
Infection and immunity 1991;59(12):4497-504.
1991: JT van Oirschot; R J M Moormann; A J Berns; A L J Gielkens
Efficacy of a pseudorabies virus vaccine based on deletion mutant strain 783 that does not express thymidine kinase and glycoprotein I.
American journal of veterinary research 1991;52(7):1056-60.
1991: M van Zijl; G Wensvoort; E de Kluyver; MM Hulst; H van der Gulden; A L J Gielkens; Anton Berns; R J M Moormann
Live attenuated pseudorabies virus expressing envelope glycoprotein E1 of hog cholera virus protects swine against both pseudorabies and hog cholera.
Journal of virology 1991;65(5):2761-5.
1991: Tjeerd G Kimman; G J Binkhorst; T S G A M van den Ingh; J M A Pol; A L J Gielkens; M E Roelvink
Aujeszky's disease in horses fulfils Koch's postulates.
The Veterinary record 1991;128(5):103-6.
1991: J M A Pol; F Wagenaar; A L J Gielkens
Morphogenesis of three pseudorabies virus strains in porcine nasal mucosa.
Intervirology 1991;32(6):327-37.
1990: JT van Oirschot; C Terpstra; R J M Moormann; A J Berns; A L J Gielkens
Safety of an Aujeszky's disease vaccine based on deletion mutant strain 783 which does not express thymidine kinase and glycoprotein I.
The Veterinary record 1990;127(18):443-6.
1990: Niels De Wind; A Zijderveld; K Glazenburg; A L J Gielkens; Anton Berns
Linker insertion mutagenesis of herpesviruses: inactivation of single genes within the Us region of pseudorabies virus.
Journal of virology 1990;64(10):4691-6.
1990: M van Zijl; H van der Gulden; Niels De Wind; A L J Gielkens; Anton Berns
Identification of two genes in the unique short region of pseudorabies virus; comparison with herpes simplex virus and varicella-zoster virus.
The Journal of general virology 1990;71 ( Pt 8)():1747-55.
1990: R J M Moormann; T de Rover; J Briaire; Ben P H Peeters; A L J Gielkens; JT van Oirschot
Inactivation of the thymidine kinase gene of a gI deletion mutant of pseudorabies virus generates a safe but still highly immunogenic vaccine strain.
The Journal of general virology 1990;71 ( Pt 7)():1591-5.
1990: JT van Oirschot; A L J Gielkens; R J M Moormann; A J Berns
Marker vaccines, virus protein-specific antibody assays and the control of Aujeszky's disease.
Veterinary microbiology 1990;23(1-4):85-101.
1990: L Jacobs; R H Meloen; A L J Gielkens; JT van Oirschot
Epitope analysis of glycoprotein I of pseudorabies virus.
The Journal of general virology 1990;71 ( Pt 4)():881-7.
1989: J M A Pol; A L J Gielkens; J T van Oirschot
Comparative pathogenesis of three strains of pseudorabies virus in pigs.
Microbial pathogenesis 1989;7(5):361-71.
1988: M van Zijl; W Quint; J Briaire; T de Rover; A L J Gielkens; Anton Berns
Regeneration of herpesviruses from molecularly cloned subgenomic fragments.
Journal of virology 1988;62(6):2191-5.
1987: JT van Oirschot; A L J Gielkens
Vaccines against Aujeszky's disease: comparison of efficacy, DNA fingerprints and antibody response to glycoprotein I.
The Veterinary quarterly 1987;9 Suppl 1():37S-49S.
1987: W Quint; A L J Gielkens; J Van Oirschot; Anton Berns; H T Cuypers
Construction and characterization of deletion mutants of pseudorabies virus: a new generation of 'live' vaccines.
The Journal of general virology 1987;68 ( Pt 2)():523-34.
1985: F Westenbrink; J M Brinkhof; A L J Gielkens
Gel electrophoretic analysis of polypeptides from nucleocapsids of Marek's disease virus strains and herpesvirus of turkey.
Archives of virology 1985;84(3-4):217-31.
1985: A L J Gielkens; JT van Oirschot; A J Berns
Genome differences among field isolates and vaccine strains of pseudorabies virus.
The Journal of general virology 1985;66 ( Pt 1)():69-82.
1985: Anton Berns; A van den Ouweland; W Quint; J van Oirschot; A L J Gielkens
Presence of markers for virulence in the unique short region or repeat region or both of pseudorabies hybrid viruses.
Journal of virology 1985;53(1):89-93.
1984: G F de Boer; A L J Gielkens; H M Boerrigter; L Hartog
Identification of avian leukosis virus shedding hens. Comparison of ALV gs-antigen levels in various test samples.
Avian pathology : journal of the W.V.P.A 1984;13(2):321-32.
1983: G F de Boer; A L J Gielkens; L Hartog; H M Boerrigter
The use of ELISA for detection of exogenous and endogenous avian leukosis viral antigens in basic breeding flocks.
Avian pathology : journal of the W.V.P.A 1983;12(4):447-59.
1982: S J Barteling; F Wagenaar; A L J Gielkens
The positively charged structural virus protein (VP1) of foot-and-mouth disease virus (type O1) contains a highly basic part which may be involved in early virus-cell interaction.
The Journal of general virology 1982;62 (Pt 2)():357-61.
1982: D Van Zaane; J M Brinkhof; A L J Gielkens
Molecular-biological characterization of Marek's disease virus. II. Differentiation of various MDV and HVT strains.
Virology 1982;121(1):133-46.
1982: D Van Zaane; J M Brinkhof; F Westenbrink; A L J Gielkens
Molecular-biological characterization of Marek's disease virus. I. Identification of virus-specific polypeptides in infected cells.
Virology 1982;121(1):116-32.
1981: A L J Gielkens; A A Ressang; J Ijzermann; J Quak
Test protocol of an enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies against bovine leukosis virus.
The Veterinary quarterly 1981;3(1):34-7.
1981: A A Ressang; A L J Gielkens; J Quak; N Mastenbroek
Studies on bovine leukosis. VII. Further experience with an ELISA for the detection of antibodies to bovine leukosis virus.
The Veterinary quarterly 1981;3(1):31-3.