Thomas Giese

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Hug Andreas; Dalpke Alexander; Wieczorek Nina; Giese Thomas; Lorenz Alexander; Auffarth Gerd; Liesz Arthur; Veltkamp Roland
Infarct volume is a major determiner of post-stroke immune cell function and susceptibility to infection.
Giese Thomas; Sommerer Claudia; Zeier Martin; Meuer Stefan
Monitoring immunosuppression with measures of NFAT decreases cancer incidence.
Kolb Armin; Rieder Simon; Born Diana; Giese Nathalia A; Giese Thomas; Rudofsky Gottfried; Werner Jens; Büchler Markus W; Friess Helmut; Esposito Irene; Jörg Kleeff
Glucagon/insulin ratio as a potential biomarker for pancreatic cancer in patients with new-onset diabetes mellitus.

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2009: Hug Andreas; Dalpke Alexander; Wieczorek Nina; Giese Thomas; Lorenz Alexander; Auffarth Gerd; Liesz Arthur; Veltkamp Roland
Infarct volume is a major determiner of post-stroke immune cell function and susceptibility to infection.
Stroke; a journal of cerebral circulation 2009;40(10):3226-32.
2009: Giese Thomas; Sommerer Claudia; Zeier Martin; Meuer Stefan
Monitoring immunosuppression with measures of NFAT decreases cancer incidence.
Clinical immunology (Orlando, Fla.) 2009;132(3):305-11.
2009: Kolb Armin; Rieder Simon; Born Diana; Giese Nathalia A; Giese Thomas; Rudofsky Gottfried; Werner Jens; Büchler Markus W; Friess Helmut; Esposito Irene; Jörg Kleeff
Glucagon/insulin ratio as a potential biomarker for pancreatic cancer in patients with new-onset diabetes mellitus.
Cancer biology & therapy 2009;8(16):1527-33.
2009: Halme Jarkko; Sachse Michael; Vogel Heiko; Giese Thomas; Klar Ernst; Kirschfink Michael
Primary human hepatocytes are protected against complement by multiple regulators.
Molecular immunology 2009;46(11-12):2284-9.
2009: Oberlies Johanna; Watzl Carsten; Giese Thomas; Luckner Claudia; Kropf Pascale; Müller Ingrid; Ho Anthony D; Munder Markus
Regulation of NK cell function by human granulocyte arginase.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(9):5259-67.
2009: Berger Michael; Ablasser Andrea; Kim Sarah; Bekeredjian-Ding Isabelle; Giese Thomas; Endres Stefan; Hornung Veit; Hartmann Gunther
TLR8-driven IL-12-dependent reciprocal and synergistic activation of NK cells and monocytes by immunostimulatory RNA.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(3):262-71.
2009: Ceyhan Güralp O; Deucker Stefanie; Demir Ihsan Ekin; Erkan Mert; Schmelz Martin; Bergmann Frank; Müller Michael W; Giese Thomas; Büchler Markus W; Giese Nathalia A; Friess Helmut
Neural fractalkine expression is closely linked to pain and pancreatic neuritis in human chronic pancreatitis.
Laboratory investigation; a journal of technical methods and pathology 2009;89(3):347-61.
2009: Raemer Patrick C; Haemmerling Susanne; Giese Thomas; Canaday David H; Katus Hugo A; Dengler Thomas J; Shankar Sivanandam G Vijay
Endothelial progenitor cells possess monocyte-like antigen-presenting and T-cell-co-stimulatory capacity.
Transplantation 2009;87(3):340-9.
2009: Liesz Arthur; Suri-Payer Elisabeth; Veltkamp Claudia; Doerr Henrike; Sommer Clemens; Rivest Serge; Giese Thomas; Veltkamp Roland
Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke.
Nature medicine 2009;15(2):192-9.
2009: Ceyhan Güralp O; Bergmann Frank; Kadihasanoglu Mustafa; Altintas Burak; Demir Ihsan E; Hinz Ulf; Müller Michael W; Giese Thomas; Büchler Markus W; Giese Nathalia A; Friess Helmut
Pancreatic neuropathy and neuropathic pain--a comprehensive pathomorphological study of 546 cases.
Gastroenterology 2009;136(1):177-186.e1.
2009: Treede Irina; Braun Annika; Jeliaskova Petia; Giese Thomas; Füllekrug Joachim; Griffiths Gareth; Stremmel Wolfgang; Ehehalt Robert
TNF-alpha-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells.
BMC gastroenterology 2009;9():53.
2009: Zahn Alexandra; Giese Thomas; Karner Max; Braun Annika; Hinz Ulf; Stremmel Wolfgang; Ehehalt Robert
Transcript levels of different cytokines and chemokines correlate with clinical and endoscopic activity in ulcerative colitis.
BMC gastroenterology 2009;9():13.
2008: Michalski C W; Erkan M; Sauliunaite D; Giese T; Stratmann R; Sartori C; Giese N A; Friess H; Kleeff J
Ex vivo chemosensitivity testing and gene expression profiling predict response towards adjuvant gemcitabine treatment in pancreatic cancer.
British journal of cancer 2008;99(5):760-7.
2008: Loos Martin; Giese Nathalia A; Kleeff Jörg; Giese Thomas; Gaida Matthias M; Bergmann Frank; Laschinger Melanie; W Büchler Markus; Friess Helmut
Clinical significance and regulation of the costimulatory molecule B7-H1 in pancreatic cancer.
Cancer letters 2008;268(1):98-109.
2008: Sommerer Claudia; Hartschuh Wolfgang; Enk Alexander; Meuer Stefan; Zeier Martin; Giese Thomas
Pharmacodynamic immune monitoring of NFAT-regulated genes predicts skin cancer in elderly long-term renal transplant recipients.
Clinical transplantation 2008;22(5):549-54.
2008: Wente Moritz N; Gaida Matthias M; Mayer Christine; Michalski Christoph W; Haag Natascha; Giese Thomas; Felix Klaus; Bergmann Frank; Giese Nathalia A; Friess Helmut
Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma.
International journal of oncology 2008;33(2):297-308.
2008: Mörmann Maik; Thederan Mareike; Nackchbandi Inaam; Giese Thomas; Wagner Christof; Hänsch G Maria
Lipopolysaccharides (LPS) induce the differentiation of human monocytes to osteoclasts in a tumour necrosis factor (TNF) alpha-dependent manner: a link between infection and pathological bone resorption.
Molecular immunology 2008;45(12):3330-7.
2008: Sommerer C; Morath C; Giese T; Meuer S; Zeier M
Activity of nuclear factor of activated T cells is independent of the number of peripheral lymphocytes in FTY720-treated patients.
Transplantation proceedings 2008;40(5):1416-8.
2008: Bartel M; Hänsch G M; Giese T; Penzel R; Ceyhan Go; Ketterer K; von Knebel-Döberitz M; Friess H M; Giese N A
Abnormal crosstalk between pancreatic acini and macrophages during the clearance of apoptotic cells in chronic pancreatitis.
The Journal of pathology 2008;215(2):195-203.
2008: Braunstein J; Autschbach F; Giese T; Lasitschka F; Heidtmann A; Sido B; Funke B; Reiser C; Schröder A J; Nebl G; Samstag Y; Meuer S C
Up-regulation of the phosphoinositide 3-kinase pathway in human lamina propria T lymphocytes.
Clinical and experimental immunology 2008;151(3):496-504.
2008: Wente Moritz N; Mayer Christine; Gaida Matthias M; Michalski Christoph W; Giese Thomas; Bergmann Frank; Giese Nathalia A; Büchler Markus W; Friess Helmut
CXCL14 expression and potential function in pancreatic cancer.
Cancer letters 2008;259(2):209-17.
2008: Sommerer Claudia; Giese Thomas; Schmidt Jan; Meuer Stefan; Zeier Martin
Ciclosporin A tapering monitored by NFAT-regulated gene expression: a new concept of individual immunosuppression.
Transplantation 2008;85(1):15-21.
2008: Sido Bernd; Lasitschka Felix; Giese Thomas; Gassler Nikolaus; Funke Benjamin; Schröder-Braunstein Jutta; Brunnemer Ulf; Meuer Stefan C; Autschbach Frank
A prominent role for mucosal cystine/cysteine metabolism in intestinal immunoregulation.
Gastroenterology 2008;134(1):179-91.
2008: Michalski Christoph W; Selvaggi Federico; Bartel Michael; Mitkus Tomas; Gorbachevski Andrej; Giese Thomas; Sebastiano Pierluigi Di; Giese Nathalia A; Friess Helmut
Altered anti-inflammatory response of mononuclear cells to neuropeptide PACAP is associated with deregulation of NF-{kappa}B in chronic pancreatitis.
American journal of physiology. Gastrointestinal and liver physiology 2008;294(1):G50-7.
2008: Michalski Christoph W; Maier Milena; Erkan Mert; Sauliunaite Danguole; Bergmann Frank; Pacher Pal; Batkai Sandor; Giese Nathalia A; Giese Thomas; Friess Helmut; Kleeff Jörg
Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells.
PloS one 2008;3(2):e1701.
2007: Veltkamp C; Ruhwald R; Veltkamp R; Giese T; Stremmel W
Regulatory CD4+ CD25+ T cells prevent thymic dysfunction in experimental chronic colitis.
Scandinavian journal of immunology 2007;66(6):636-44.
2007: Konstandin Mathias H; Sommerer Claudia; Doesch Andreas; Zeier Martin; Meuer Stefan C; Katus Hugo A; Dengler Thomas J; Giese Thomas
Pharmacodynamic cyclosporine A-monitoring: relation of gene expression in lymphocytes to cyclosporine blood levels in cardiac allograft recipients.
Transplant international : official journal of the European Society for Organ Transplantation 2007;20(12):1036-43.
2007: Müller Michael W; Giese Nathalia A; Swiercz Jakub M; Ceyhan Güralp O; Esposito Irene; Hinz Ulf; Büchler Peter; Giese Thomas; Büchler Markus W; Offermanns Stefan; Friess Helmut
Association of axon guidance factor semaphorin 3A with poor outcome in pancreatic cancer.
International journal of cancer. Journal international du cancer 2007;121(11):2421-33.
2007: Kayed H; Jiang X; Keleg S; Jesnowski R; Giese T; Berger M R; Esposito I; Löhr M; Friess H; Kleeff J
Regulation and functional role of the Runt-related transcription factor-2 in pancreatic cancer.
British journal of cancer 2007;97(8):1106-15.
2007: Welsch Thilo; Endlich Karlhans; Giese Thomas; Büchler Markus W; Schmidt Jan
Eps8 is increased in pancreatic cancer and required for dynamic actin-based cell protrusions and intercellular cytoskeletal organization.
Cancer letters 2007;255(2):205-18.
2007: Treede Irina; Braun Annika; Sparla Richard; Kühnel Mark; Giese Thomas; Turner Jerrold R; Anes Elsa; Kulaksiz Hasan; Füllekrug Joachim; Stremmel Wolfgang; Griffiths Gareth; Ehehalt Robert
Anti-inflammatory effects of phosphatidylcholine.
The Journal of biological chemistry 2007;282(37):27155-64.
2007: Keleg Shereen; Kayed Hany; Jiang Xiaohua; Penzel Roland; Giese Thomas; Büchler Markus W; Friess Helmut; Kleeff Jörg
Adrenomedullin is induced by hypoxia and enhances pancreatic cancer cell invasion.
International journal of cancer. Journal international du cancer 2007;121(1):21-32.
2007: Michalski Christoph W; Laukert Tamara; Sauliunaite Danguole; Pacher Pál; Bergmann Frank; Agarwal Nitin; Su Yun; Giese Thomas; Giese Nathalia A; Bátkai Sándor; Friess Helmut; Kuner Rohini
Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis.
Gastroenterology 2007;132(5):1968-78.
2007: Erkan Mert; Kleeff Jörg; Gorbachevski Andre; Reiser Carolin; Mitkus Tomas; Esposito Irene; Giese Thomas; Büchler Markus W; Giese Nathalia A; Friess Helmut
Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity.
Gastroenterology 2007;132(4):1447-64.
2007: Michalski Christoph W; Autschbach Frank; Selvaggi Federico; Shi Xin; Di Mola Fabio Francesco; Roggo Antoine; Müller Michael W; Di Sebastiano Pierluigi; Büchler Markus W; Giese Thomas; Friess Helmut
Increase in substance P precursor mRNA in noninflamed small-bowel sections in patients with Crohn's disease.
American journal of surgery 2007;193(4):476-81.
2007: Ceyhan Güralp O; Bergmann Frank; Kadihasanoglu Mustafa; Erkan Mert; Park Weon; Hinz Ulf; Giese Thomas; Müller Michael W; Büchler Markus W; Giese Nathalia A; Friess Helmut
The neurotrophic factor artemin influences the extent of neural damage and growth in chronic pancreatitis.
Gut 2007;56(4):534-44.
2007: Kusumawidjaja Grace; Kayed Hany; Giese Nathalia; Bauer Andrea; Erkan Mert; Giese Thomas; Hoheise Jörg D; Friess Helmut; Kleeff Jörg
Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells.
Cancer biology & therapy 2007;6(3):367-76.
2007: Bekeredjian-Ding Isabelle; Inamura Seiichi; Giese Thomas; Moll Hermann; Endres Stefan; Sing Andreas; Zähringer Ulrich; Hartmann Gunther
Staphylococcus aureus protein A triggers T cell-independent B cell proliferation by sensitizing B cells for TLR2 ligands.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(5):2803-12.
2007: Kolb Armin; Kleeff Jörg; Arnold Nichole; Giese Nathalia A; Giese Thomas; Korc Murray; Friess Helmut
Expression and differential signaling of heregulins in pancreatic cancer cells.
International journal of cancer. Journal international du cancer 2007;120(3):514-23.
2007: Esposito Irene; Kayed Hany; Keleg Shereen; Giese Thomas; Sage E Helene; Schirmacher Peter; Friess Helmut; Kleeff Jörg
Tumor-suppressor function of SPARC-like protein 1/Hevin in pancreatic cancer.
Neoplasia (New York, N.Y.) 2007;9(1):8-17.
2007: Endt Johanna; Eissmann Philipp; Hoffmann Sabrina C; Meinke Stephan; Giese Thomas; Watzl Carsten
Modulation of 2B4 (CD244) activity and regulated SAP expression in human NK cells.
European journal of immunology 2007;37(1):193-8.
2007: Gleissner Christian A; Zastrow Arne; Klingenberg Roland; Kluger Martin S; Konstandin Mathias; Celik Sultan; Haemmerling Susanne; Shankar Vijay; Giese Thomas; Katus Hugo A; Dengler Thomas J
IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells.
European journal of immunology 2007;37(1):177-92.
2007: Künzli Beat M; Berberat Pascal O; Giese Thomas; Csizmadia Eva; Kaczmarek Elzbieta; Baker Colin; Halaceli Irfan; Büchler Markus W; Friess Helmut; Robson Simon C
Upregulation of CD39/NTPDases and P2 receptors in human pancreatic disease.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(1):G223-30.
2007: Kayed Hany; Kleeff Jörg; Keleg Shereen; Felix Klaus; Giese Thomas; Berger Martin R; Büchler Markus W; Friess Helmut
Effects of bone sialoprotein on pancreatic cancer cell growth, invasion and metastasis.
Cancer letters 2007;245(1-2):171-83.
2007: Kayed Hany; Bekasi Sandor; Keleg Shereen; Michalski Christoph W; Giese Thomas; Friess Helmut; Kleeff Jörg
BGLAP is expressed in pancreatic cancer cells and increases their growth and invasion.
Molecular cancer 2007;6():83.
2007: Michalski Christoph W; Gorbachevski Andre; Erkan Mert; Reiser Carolin; Deucker Stefanie; Bergmann Frank; Giese Thomas; Weigand Markus; Giese Nathalia A; Friess Helmut; Kleeff Jörg
Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis.
Journal of translational medicine 2007;5():63.
2006: Sommerer Claudia; Konstandin Mathias; Dengler Thomas; Schmidt Jan; Meuer Stefan; Zeier Martin; Giese Thomas
Pharmacodynamic monitoring of cyclosporine a in renal allograft recipients shows a quantitative relationship between immunosuppression and the occurrence of recurrent infections and malignancies.
Transplantation 2006;82(10):1280-5.
2006: Su Yun; Büchler Peter; Gazdhar Amiq; Giese Nathalia; Reber Howard A; Hines Oscar J; Giese Thomas; Büchler Markus W; Friess Helmut
Pancreatic regeneration in chronic pancreatitis requires activation of the notch signaling pathway.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2006;10(9):1230-41; discussion 1242.
2006: Kayed Hany; Kleeff Jörg; Keleg Shereen; Jiang Xiaohua; Penzel Roland; Giese Thomas; Zentgraf Hanswalter; Büchler Markus W; Korc Murray; Friess Helmut
Correlation of glypican-1 expression with TGF-beta, BMP, and activin receptors in pancreatic ductal adenocarcinoma.
International journal of oncology 2006;29(5):1139-48.
2006: Shrikhande Shailesh V; Kleeff Jörg; Kayed Hany; Keleg Shereen; Reiser Carolin; Giese Thomas; Büchler Markus W; Esposito Irene; Friess Helmut
Silencing of X-linked inhibitor of apoptosis (XIAP) decreases gemcitabine resistance of pancreatic cancer cells.
Anticancer research 2006;26(5A):3265-73.
2006: Berberat Pascal O; Friess Helmut; Schmied Bruno; Kremer Michael; Gragert Stefanie; Flechtenmacher Christa; Schemmer Peter; Schmidt Jan; Kraus Thomas; Uhl Waldemar; Meuer Stefan; Büchler Markus W; Giese Thomas
Differentially expressed genes in postperfusion biopsies predict early graft dysfunction after liver transplantation.
Transplantation 2006;82(5):699-704.
2006: Munder Markus; Schneider Henriette; Luckner Claudia; Giese Thomas; Langhans Claus-Dieter; Fuentes Jose M; Kropf Pascale; Mueller Ingrid; Kolb Armin; Modolell Manuel; Ho Anthony D
Suppression of T-cell functions by human granulocyte arginase.
Blood 2006;108(5):1627-34.
2006: Ceyhan Güralp O; Giese Nathalia A; Erkan Mert; Kerscher Annika G; Wente Moritz N; Giese Thomas; Büchler Markus W; Friess Helmut
The neurotrophic factor artemin promotes pancreatic cancer invasion.
Annals of surgery 2006;244(2):274-81.
2006: Bekeredjian-Ding Isabelle; Roth Susanne Ilona; Gilles Stefanie; Giese Thomas; Ablasser Andrea; Hornung Veit; Endres Stefan; Hartmann Gunther
T cell-independent, TLR-induced IL-12p70 production in primary human monocytes.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7438-46.
2006: Guo Junchao; Kleeff Jörg; Zhao Yupei; Li Junsheng; Giese Thomas; Esposito Irene; Büchler Markus W; Korc Murray; Friess Helmut
Yes-associated protein (YAP65) in relation to Smad7 expression in human pancreatic ductal adenocarcinoma.
International journal of molecular medicine 2006;17(5):761-7.
2006: Schneider Martin; Büchler Peter; Giese Nathalia; Giese Thomas; Wilting Jörg; Büchler Markus W; Friess Helmut
Role of lymphangiogenesis and lymphangiogenic factors during pancreatic cancer progression and lymphatic spread.
International journal of oncology 2006;28(4):883-90.
2006: Wagner Christof; Ochmann Carsten; Schoels Margarita; Giese Thomas; Stegmaier Sabine; Richter Rosi; Hug Friederike; Hänsch G Maria
The complement receptor 1, CR1 (CD35), mediates inhibitory signals in human T-lymphocytes.
Molecular immunology 2006;43(6):643-51.
2006: Gulbinas Antanas; Berberat Pascal O; Dambrauskas Zilvinas; Giese Thomas; Giese Nathalia; Autschbach Frank; Kleeff Joerg; Meuer Stefan; Büchler Markus W; Friess Helmut
Aberrant gata-3 expression in human pancreatic cancer.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(2):161-9.
2006: Köninger J; Giese N A; Bartel M; di Mola F F; Berberat P O; di Sebastiano P; Giese T; Büchler M W; Friess H
The ECM proteoglycan decorin links desmoplasia and inflammation in chronic pancreatitis.
Journal of clinical pathology 2006;59(1):21-7.
2006: Kayed Hany; Kleeff Jörg; Kolb Armin; Ketterer Knut; Keleg Shereen; Felix Klaus; Giese Thomas; Penzel Roland; Zentgraf Hanswalter; Büchler Markus W; Korc Murray; Friess Helmut
FXYD3 is overexpressed in pancreatic ductal adenocarcinoma and influences pancreatic cancer cell growth.
International journal of cancer. Journal international du cancer 2006;118(1):43-54.
2006: Michalski Christoph W; Di Mola Fabio Francesco; Kümmel Klaus; Wendt Michael; Köninger Jörg S; Giese Thomas; Giese Nathalia A; Friess Helmut
Human inflammatory bowel disease does not associate with Lawsonia intracellularis infection.
BMC microbiology 2006;6():81.
2005: Büchler Peter; Gazdhar Amiq; Schubert Mario; Giese Nathalia; Reber Howard A; Hines Oscar J; Giese Thomas; Ceyhan Güralp O; Müller Michael; Büchler Markus W; Friess Helmut
The Notch signaling pathway is related to neurovascular progression of pancreatic cancer.
Annals of surgery 2005;242(6):791-800, discussion 800-1.
2005: Martignoni Marc E; Kunze Phillipp; Hildebrandt Wulf; Künzli Beat; Berberat Pascal; Giese Thomas; Klöters Oliver; Hammer Jürgen; Büchler Markus W; Giese Nathalia A; Friess Helmut
Role of mononuclear cells and inflammatory cytokines in pancreatic cancer-related cachexia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(16):5802-8.
2005: Guweidhi Ahmed; Kleeff Jörg; Adwan Hassan; Giese Nathalia A; Wente Moritz N; Giese Thomas; Büchler Markus W; Berger Martin R; Friess Helmut
Osteonectin influences growth and invasion of pancreatic cancer cells.
Annals of surgery 2005;242(2):224-34.
2005: Marschner Anja; Rothenfusser Simon; Hornung Veit; Prell Domenik; Krug Anne; Kerkmann Miren; Wellisch Daniela; Poeck Hendrik; Greinacher Andreas; Giese Thomas; Endres Stefan; Hartmann Gunther
CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells.
European journal of immunology 2005;35(8):2347-57.
2005: Wente Moritz N; Jain Anjali; Kono Evelyn; Berberat Pascal O; Giese Thomas; Reber Howard A; Friess Helmut; Büchler Markus W; Reiter Robert E; Hines Oscar J
Prostate stem cell antigen is a putative target for immunotherapy in pancreatic cancer.
Pancreas 2005;31(2):119-25.
2005: Li Junsheng; Kleeff Jörg; Esposito Irene; Kayed Hany; Felix Klaus; Giese Thomas; Büchler Markus W; Friess Helmut
Expression analysis of PMP22/Gas3 in premalignant and malignant pancreatic lesions.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(7):885-93.
2005: Kolb A; Kleeff J; Guweidhi A; Esposito I; Giese N A; Adwan H; Giese T; Büchler M W; Berger M R; Friess H
Osteopontin influences the invasiveness of pancreatic cancer cells and is increased in neoplastic and inflammatory conditions.
Cancer biology & therapy 2005;4(7):740-6.
2005: Autschbach F; Eisold S; Hinz U; Zinser S; Linnebacher M; Giese T; Löffler T; Büchler M W; Schmidt J
High prevalence of Mycobacterium avium subspecies paratuberculosis IS900 DNA in gut tissues from individuals with Crohn's disease.
Gut 2005;54(7):944-9.
2005: Klingenberg Roland; Autschbach Frank; Gleissner Christian; Giese Thomas; Wambsganss Nadine; Sommer Natascha; Richter Guenther; Katus Hugo A; Dengler Thomas J
Endothelial inducible costimulator ligand expression is increased during human cardiac allograft rejection and regulates endothelial cell-dependent allo-activation of CD8+ T cells in vitro.
European journal of immunology 2005;35(6):1712-21.
2005: Erkan Mert; Kleeff Jörg; Esposito Irene; Giese Thomas; Ketterer Knut; Büchler Markus W; Giese Nathalla A; Friess Helmut
Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis.
Oncogene 2005;24(27):4421-32.
2005: Berberat Pascal O; Dambrauskas Zilvinas; Gulbinas Antanas; Giese Thomas; Giese Nathalia; Künzli Beat; Autschbach Frank; Meuer Stefen; Büchler Markus W; Friess Helmut
Inhibition of heme oxygenase-1 increases responsiveness of pancreatic cancer cells to anticancer treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(10):3790-8.
2005: Bekeredjian-Ding Isabelle Béatrice; Wagner Moritz; Hornung Veit; Giese Thomas; Schnurr Max; Endres Stefan; Hartmann Gunther
Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):4043-50.
2005: Kayed Hany; Kleeff Jörg; Esposito Irene; Giese Thomas; Keleg Shereen; Giese Nathalia; Büchler Markus W; Friess Helmut
Localization of the human hedgehog-interacting protein (Hip) in the normal and diseased pancreas.
Molecular carcinogenesis 2005;42(4):183-92.
2005: Giese Thomas; Engstner Monika; Mansmann Ulrich; Hartschuh Wolfgang; Arden Bernhard
Quantification of melanoma micrometastases in sentinel lymph nodes using real-time RT-PCR.
The Journal of investigative dermatology 2005;124(3):633-7.
2005: Raykov Zahari; Savelyeva Larissa; Balboni Ginette; Giese Thomas; Rommelaere Jean; Giese Nathalia A
B1 lymphocytes and myeloid dendritic cells in lymphoid organs are preferential extratumoral sites of parvovirus minute virus of mice prototype strain expression.
Journal of virology 2005;79(6):3517-24.
2005: Jahrsdorfer Bernd; Mühlenhoff Lars; Blackwell Sue E; Wagner Moritz; Poeck Hendrik; Hartmann Evelyn; Jox Ralf; Giese Thomas; Emmerich Bertold; Endres Stefan; Weiner George J; Hartmann Gunther
B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(4):1490-9.
2005: Veltkamp C; Sartor R B; Giese T; Autschbach F; Kaden I; Veltkamp R; Rost D; Kallinowski B; Stremmel W
Regulatory CD4+CD25+ cells reverse imbalances in the T cell pool of bone marrow transplanted TGepsilon26 mice leading to the prevention of colitis.
Gut 2005;54(2):207-14.
2005: Sido Bernd; Giese Thomas; Autschbach Frank; Lasitschka Felix; Braunstein Jutta; Meuer Stefan C
Potential role of thioredoxin in immune responses in intestinal lamina propria T lymphocytes.
European journal of immunology 2005;35(2):408-17.
2005: Li Junsheng; Kleeff Jörg; Abiatari Ivane; Kayed Hany; Giese Nathalia A; Felix Klaus; Giese Thomas; Büchler Markus W; Friess Helmut
Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer.
Molecular cancer 2005;4(1):14.
2004: Kayed H; Kleeff J; Ding J; Hammer J; Giese T; Zentgraf H; Büchler M W; Friess H
Expression analysis of MAC30 in human pancreatic cancer and tumors of the gastrointestinal tract.
Histology and histopathology 2004;19(4):1021-31.
2004: Schoels M; Dengler T J; Richter R; Meuer S C; Giese T
Detection of cardiac allograft rejection by real-time PCR analysis of circulating mononuclear cells.
Clinical transplantation 2004;18(5):513-7.
2004: Köninger Jörg; Giese Thomas; di Mola Fabio F; Wente Moritz N; Esposito Irene; Bachem Max G; Giese Nathalia A; Büchler Markus W; Friess Helmut
Pancreatic tumor cells influence the composition of the extracellular matrix.
Biochemical and biophysical research communications 2004;322(3):943-9.
2004: Guweidhi Ahmed; Kleeff Jörg; Giese Nathalia; El Fitori Jamael; Ketterer Knut; Giese Thomas; Büchler Markus W; Korc Murray; Friess Helmut
Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis.
Carcinogenesis 2004;25(9):1575-85.
2004: Hartel Mark; Di Mola Fabio F; Gardini Andrea; Zimmermann Arthur; Di Sebastiano Pierluigi; Guweidhi Ahmed; Innocenti Paolo; Giese Thomas; Giese Nathalia; Büchler Markus W; Friess Helmut
Desmoplastic reaction influences pancreatic cancer growth behavior.
World journal of surgery 2004;28(8):818-25.
2004: Köninger Jörg; Giese Nathalia A; di Mola Fabio Francesco; Berberat Pascal; Giese Thomas; Esposito Irene; Bachem Max G; Büchler Markus W; Friess Helmut
Overexpressed decorin in pancreatic cancer: potential tumor growth inhibition and attenuation of chemotherapeutic action.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4776-83.
2004: Giese Thomas; Zeier Martin; Meuer Stefan
Analysis of NFAT-regulated gene expression in vivo: a novel perspective for optimal individualized doses of calcineurin inhibitors.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19 Suppl 4():iv55-60.
2004: Kayed Hany; Kleeff Jörg; Keleg Shereen; Guo Junchau; Ketterer Knut; Berberat Pascal O; Giese Nathalia; Esposito Irene; Giese Thomas; Büchler Markus W; Friess Helmut
Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer.
International journal of cancer. Journal international du cancer 2004;110(5):668-76.
2004: Giese Thomas; McGrath Michael S; Stumm Susanne; Schempp Harald; Elstner Erich; Meuer Stefan C
Differential effects on innate versus adaptive immune responses by WF10.
Cellular immunology 2004;229(2):149-58.
2004: Eisold Sven; Ryschich Eduard; Linnebacher Michael; Giese Thomas; Nauheimer Dirk; Wild Anja; Bartsch Detlef K; Büchler Markus W; Schmidt Jan
Characterization of FAMPAC, a newly identified human pancreatic carcinoma cell line with a hereditary background.
Cancer 2004;100(9):1978-86.
2004: Poeck Hendrik; Wagner Moritz; Battiany Julia; Rothenfusser Simon; Wellisch Daniela; Hornung Veit; Jahrsdorfer Bernd; Giese Thomas; Endres Stefan; Hartmann Gunther
Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help.
Blood 2004;103(8):3058-64.
2004: Li J; Kleeff J; Guweidhi A; Esposito I; Berberat P O; Giese T; Büchler M W; Friess H
RUNX3 expression in primary and metastatic pancreatic cancer.
Journal of clinical pathology 2004;57(3):294-9.
2004: Giese Thomas; Zeier Martin; Schemmer Peter; Uhl Waldemar; Schoels Margarita; Dengler Thomas; Buechler Markus; Meuer Stefan
Monitoring of NFAT-regulated gene expression in the peripheral blood of allograft recipients: a novel perspective toward individually optimized drug doses of cyclosporine A.
Transplantation 2004;77(3):339-44.
2004: Eibert Sybille M; Lee Kyeong-Hee; Pipkorn Rüdiger; Sester Urban; Wabnitz Guido H; Giese Thomas; Meuer Stefan C; Samstag Yvonne
Cofilin peptide homologs interfere with immunological synapse formation and T cell activation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):1957-62.
2004: Guo Junchao; Kleeff Jörg; Li Junsheng; Ding Jiayi; Hammer Jürgen; Zhao Yupei; Giese Thomas; Korc Murray; Büchler Markus W; Friess Helmut
Expression and functional significance of CDC25B in human pancreatic ductal adenocarcinoma.
Oncogene 2004;23(1):71-81.
2004: Wagner Moritz; Poeck Hendrik; Jahrsdoerfer Bernd; Rothenfusser Simon; Prell Domenik; Bohle Barbara; Tuma Evelyn; Giese Thomas; Ellwart Joachim W; Endres Stefan; Hartmann Gunther
IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):954-63.
2003: Hartmann Evelyn; Wollenberg Barbara; Rothenfusser Simon; Wagner Moritz; Wellisch Daniela; Mack Brigitte; Giese Thomas; Gires Olivier; Endres Stefan; Hartmann Gunther
Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer.
Cancer research 2003;63(19):6478-87.
2003: Kerkmann Miren; Rothenfusser Simon; Hornung Veit; Towarowski Andreas; Wagner Moritz; Sarris Anja; Giese Thomas; Endres Stefan; Hartmann Gunther
Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(9):4465-74.
2003: Krug Anne; Rothenfusser Simon; Selinger S; Bock C; Kerkmann M; Battiany J; Sarris A; Giese Thomas; Speiser D; Endres Stefan; Hartmann Gunther
CpG-A oligonucleotides induce a monocyte-derived dendritic cell-like phenotype that preferentially activates CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(7):3468-77.
2003: Giese Thomas; Zimmermann Kurt; Meuer Stefan C
Functional characterization of pro-biotic pharmaceuticals by quantitative analysis of gene expression.
Arzneimittel-Forschung 2003;53(5):385-91.
2002: Autschbach Frank; Giese Thomas; Gassler Nikolaus; Sido Bernd; Heuschen Gundi; Heuschen Udo; Zuna Ivan; Schulz Patricia; Weckauf Helgard; Berger Irina; Otto Herwart F; Meuer Stefan C
Cytokine/chemokine messenger-RNA expression profiles in ulcerative colitis and Crohn's disease.
Virchows Archiv : an international journal of pathology 2002;441(5):500-13.
2002: Hornung Veit; Rothenfusser Simon; Britsch Stefanie; Krug Anne; Jahrsdörfer Bernd; Giese Thomas; Endres Stefan; Hartmann Gunther
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4531-7.
2001: Krug A; Towarowski A; Britsch S; Rothenfusser S; Hornung V; Bals R; Giese T; Engelmann H; Endres S; Krieg A M; Hartmann G
Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12.
European journal of immunology 2001;31(10):3026-37.
2001: Stallmach A; Giese T; Pfister K; Wittig B M; Künne S; Humphries M; Zeitz M; Meuer S C
Activation of beta(1) integrins mediates proliferation and inhibits apoptosis of intestinal CD4-positive lymphocytes.
European journal of immunology 2001;31(4):1228-38.
1999: Ding I; Bruyns E; Li P; Magada D; Paskind M; Rodman L; Seshadri T; Alexander D; Giese T; Schraven B
Biochemical and functional analysis of mice deficient in expression of the CD45-associated phosphoprotein LPAP.
European journal of immunology 1999;29(12):3956-61.
1999: Stallmach A; Wittig B; Giese T; Pfister K; Hoffmann J C; Bulfone-Paus S; Kunzendorf U; Meuer S C; Zeitz M
Protection of trinitrobenzene sulfonic acid-induced colitis by an interleukin 2-IgG2b fusion protein in mice.
Gastroenterology 1999;117(4):866-76.

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