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José Giglio
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46
Soares, Andreimar
26
Sampaio, Suely
26
Arantes, Eliane
18
Marangoni, Sérgio
15
Rodrigues, Veridiana
15
Cintra, A C O
15
Homsi-Brandeburgo, Maria Inês
14
Andrião-Escarso, Sílvia
13
Fontes, Marcos
12
Marcussi, Silvana
12
Oliveira, B
11
Vieira, Carlos
11
Antunes, Edson
10
Rodrigues-Simioni, Léa
9
Novello, José Camillo
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All Publications
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2009: Oliveira Juliana G; Soares Sandro G; Soares Andreimar M; Giglio José R; Teixeira José E; Barbosa José E
Expression of human recombinant antibody fragments capable of partially inhibiting the phospholypase activity of Crotalus durissus terrificus venom.
Basic & clinical pharmacology & toxicology 2009;105(2):84-91.
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2009: Cologna Camila T; Marcussi Silvana; Giglio José R; Soares Andreimar M; Arantes Eliane C
Tityus serrulatus scorpion venom and toxins: an overview.
Protein and peptide letters 2009;16(8):920-32.
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2008: Alves Raquel Melo; Antonucci Gilmara Ausech; Paiva Helder Henrique; Cintra Adélia Cristina Oliveira; Franco João José; Mendonça-Franqueiro Elaine Paula; Dorta Daniel Junqueira; Giglio José Roberto; Rosa José César; Fuly André Lopes; Dias-Baruffi Marcelo; Soares Andreimar Martins; Sampaio Suely Vilela
Evidence of caspase-mediated apoptosis induced by l-amino acid oxidase isolated from Bothrops atrox snake venom.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2008;151(4):542-50.
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2008: Sant' Ana Carolina D; Ticli Fabio K; Oliveira Leandro L; Giglio Jose R; Rechia Carem G V; Fuly André L; Selistre de Araújo Heloisa S; Franco João J; Stabeli Rodrigo G; Soares Andreimar M; Sampaio Suely V
BjussuSP-I: a new thrombin-like enzyme isolated from Bothrops jararacussu snake venom.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2008;151(3):443-54.
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2007: Marcussi Silvana; Bernardes Carolina P; Santos-Filho Norival A; Mazzi Maurício V; Oliveira Clayton Z; Izidoro Luiz Fernando M; Fuly André L; Magro Angelo J; Braz Antonio S K; Fontes Marcos R M; Giglio José R; Soares Andreimar M
Molecular and functional characterization of a new non-hemorrhagic metalloprotease from Bothrops jararacussu snake venom with antiplatelet activity.
Peptides 2007;28(12):2328-39.
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2007: de Castro França Suzelei; Correa Maria Madalena; dos Santos Schivo Ieda Regina; Garcia Leme João; Giglio José Roberto
A low molecular weight proinflammatory factor from rat spleen lymphocytes. Isolation and partial characterization.
Inflammation 2007;30(3-4):87-96.
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2007: da Silva Noelson M V; Arruda Emerson Z; Murakami Yugo L B; Moraes Raphael A M; El-Kik Camila Z; Tomaz Marcelo A; Fernandes Fabrício F A; Oliveira Clayton Z; Soares Andreimar M; Giglio Jose R; Melo Paulo A
Evaluation of three Brazilian antivenom ability to antagonize myonecrosis and hemorrhage induced by Bothrops snake venoms in a mouse model.
Toxicon : official journal of the International Society on Toxinology 2007;50(2):196-205.
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2007: Rodrigues Renata S; Izidoro Luiz Fernando M; Teixeira Sabrina S; Silveira Lucas B; Hamaguchi Amélia; Homsi-Brandeburgo Maria Inês; Selistre-de-Araújo Heloísa S; Giglio José R; Fuly André L; Soares Andreimar M; Rodrigues Veridiana M
Isolation and functional characterization of a new myotoxic acidic phospholipase A(2) from Bothrops pauloensis snake venom.
Toxicon : official journal of the International Society on Toxinology 2007;50(1):153-65.
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2007: Marcussi Silvana; Sant'Ana Carolina D; Oliveira Clayton Z; Rueda Aristides Quintero; Menaldo Danilo L; Beleboni Rene O; Stabeli Rodrigo G; Giglio José R; Fontes Marcos R M; Soares Andreimar M
Snake venom phospholipase A2 inhibitors: medicinal chemistry and therapeutic potential.
Current topics in medicinal chemistry 2007;7(8):743-56.
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2006: Cecchini Alessandra L; Vasconcelos Flávio; Amara Susan G; Giglio José Roberto; Arantes Eliane Candiani
Effects of Tityus serrulatus scorpion venom and its toxin TsTX-V on neurotransmitter uptake in vitro.
Toxicology and applied pharmacology 2006;217(2):196-203.
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2006: Tamarozzi M B; Soares S G; Marcussi S; Giglio J R; Barbosa J E
Expression of recombinant human antibody fragments capable of inhibiting the phospholipase and myotoxic activities of Bothrops jararacussu venom.
Biochimica et biophysica acta 2006;1760(9):1450-7.
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2006: Stábeli Rodrigo G; Amui Saulo F; Sant'Ana Carolina D; Pires Matheus G; Nomizo Auro; Monteiro Marta C; Romão Pedro R T; Guerra-Sá Renata; Vieira Carlos A; Giglio José R; Fontes Marcos R M; Soares Andreimar M
Bothrops moojeni myotoxin-II, a Lys49-phospholipase A2 homologue: an example of function versatility of snake venom proteins.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2006;142(3-4):371-81.
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2005: Camargo Enilton A; Esquisatto Laura C M; Esquisatto Marcelo A; Ribela Maria Teresa C P; Cintra Adélia C; Giglio José R; Antunes Edson; Landucci Elen C T
Characterization of the acute pancreatitis induced by secretory phospholipases A2 in rats.
Toxicon : official journal of the International Society on Toxinology 2005;46(8):921-6.
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2005: Ticli Fábio K; Hage Lorane I S; Cambraia Rafael S; Pereira Paulo S; Magro Angelo J; Fontes Marcos R M; Stábeli Rodrigo G; Giglio José R; França Suzelei C; Soares Andreimar M; Sampaio Suely V
Rosmarinic acid, a new snake venom phospholipase A2 inhibitor from Cordia verbenacea (Boraginaceae): antiserum action potentiation and molecular interaction.
Toxicon : official journal of the International Society on Toxinology 2005;46(3):318-27.
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2005: da Silva Jocivânia O; Coppede Juliana S; Fernandes Vanessa C; Sant'ana Carolina D; Ticli Fábio K; Mazzi Maurício V; Giglio José R; Pereira Paulo S; Soares Andreimar M; Sampaio Suely V
Antihemorrhagic, antinucleolytic and other antiophidian properties of the aqueous extract from Pentaclethra macroloba.
Journal of ethnopharmacology 2005;100(1-2):145-52.
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2005: Vasconcelos Flávio; Lanchote Vera Lúcia; Bendhack Lusiane M; Giglio José Roberto; Sampaio Suely Vilela; Arantes Eliane Candiani
Effects of voltage-gated Na+ channel toxins from Tityus serrulatus venom on rat arterial blood pressure and plasma catecholamines.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2005;141(1):85-92.
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2005: Bomfim José Henrique G G; de Godoy Márcio A F; Giglio José R; de Oliveira Ana Maria; Arantes Eliane C
Effects induced by Tityus serrulatus scorpion venom and its toxins TsTX-I and TsTX-V on the rat isolated retractor penis muscle.
Pharmacology 2005;73(4):190-8.
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2005: Veronese E L G; Esmeraldino L E; Trombone A P F; Santana A E; Bechara G H; Kettelhut I; Cintra A C O; Giglio J R; Sampaio S V
Inhibition of the myotoxic activity of Bothrops jararacussu venom and its two major myotoxins, BthTX-I and BthTX-II, by the aqueous extract of Tabernaemontana catharinensis A. DC. (Apocynaceae).
Phytomedicine : international journal of phytotherapy and phytopharmacology 2005;12(1-2):123-30.
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2005: Cecchini Alessandra L; Marcussi Silvana; Silveira Lucas B; Borja-Oliveira Caroline R; Rodrigues-Simioni Léa; Amara Susan; Stábeli Rodrigo G; Giglio José R; Arantes Eliane C; Soares Andreimar M
Biological and enzymatic activities of Micrurus sp. (Coral) snake venoms.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2005;140(1):125-34.
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2005: Soares Andreimar M; Ticli Fábio K; Marcussi Silvana; Lourenço Miriam V; Januário Ana Helena; Sampaio Suely V; Giglio José R; Lomonte Bruno; Pereira Paulo S
Medicinal plants with inhibitory properties against snake venoms.
Current medicinal chemistry 2005;12(22):2625-41.
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2004: Vasconcelos Flávio; Sampaio Suely V; Garófalo Maria A R; Guimarães Luiz Fernando L; Giglio José R; Arantes Eliane C
Insulin-like effects of Bauhinia forficata aqueous extract upon Tityus serrulatus scorpion envenoming.
Journal of ethnopharmacology 2004;95(2-3):385-92.
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2004: Oshima-Franco Yoko; Leite Gildo Bernardo; Belo Cháriston André Dal; Hyslop Stephen; Prado-Franceschi Júlia; Cintra Adélia Cristina Oliveira; Giglio José Roberto; da Cruz-Höfling Maria Alice; Rodrigues-Simioni Léa
The presynaptic activity of bothropstoxin-I, a myotoxin from Bothrops jararacussu snake venom.
Basic & clinical pharmacology & toxicology 2004;95(4):175-82.
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2004: Fuly André L; Soares Andreimar M; Marcussi Silvana; Giglio José R; Guimarães Jorge A
Signal transduction pathways involved in the platelet aggregation induced by a D-49 phospholipase A2 isolated from Bothrops jararacussu snake venom.
Biochimie 2004;86(9-10):731-9.
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2004: Rodrigues Veridiana M; Marcussi Silvana; Cambraia Rafael S; de Araújo Ana L; Malta-Neto Natael R; Hamaguchi Amélia; Ferro Eloísa A V; Homsi-Brandeburgo Maria I; Giglio José R; Soares Andreimar M
Bactericidal and neurotoxic activities of two myotoxic phospholipases A2 from Bothrops neuwiedi pauloensis snake venom.
Toxicon : official journal of the International Society on Toxinology 2004;44(3):305-14.
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2004: Cecchini A L; Soares A M; Cecchini R; de Oliveira A H C; Ward R J; Giglio J R; Arantes E C
Effect of crotapotin on the biological activity of Asp49 and Lys49 phospholipases A(2) from Bothrops snake venoms.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2004;138(4):429-36.
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2004: Stábeli Rodrigo G; Marcussi Silvana; Carlos Guilherme B; Pietro Rosemeire C L R; Selistre-de-Araújo Heloísa S; Giglio José R; Oliveira Eduardo B; Soares Andreimar M
Platelet aggregation and antibacterial effects of an l-amino acid oxidase purified from Bothrops alternatus snake venom.
Bioorganic & medicinal chemistry 2004;12(11):2881-6.
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2004: Roberto Patrícia G; Kashima Simone; Marcussi Silvana; Pereira José O; Astolfi-Filho Spartaco; Nomizo Auro; Giglio José R; Fontes Marcos R M; Soares Andreimar M; França Suzelei C
Cloning and identification of a complete cDNA coding for a bactericidal and antitumoral acidic phospholipase A2 from Bothrops jararacussu venom.
The protein journal 2004;23(4):273-85.
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2004: Kashima Simone; Roberto Patrícia G; Soares Andreimar M; Astolfi-Filho Spartaco; Pereira José O; Giuliati Silvana; Faria Milton; Xavier Mauro A S; Fontes Marcos R M; Giglio José R; França Suzelei C
Analysis of Bothrops jararacussu venomous gland transcriptome focusing on structural and functional aspects: I--gene expression profile of highly expressed phospholipases A2.
Biochimie 2004;86(3):211-9.
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2004: Soares Andreimar M; Sestito Wladimir P; Marcussi Silvana; Stábeli Rodrigo G; Andrião-Escarso Silvia H; Cunha Odete A B; Vieira Carlos A; Giglio José R
Alkylation of myotoxic phospholipases A2 in Bothrops moojeni venom: a promising approach to an enhanced antivenom production.
The international journal of biochemistry & cell biology 2004;36(2):258-70.
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2004: de Almeida Lucilene; Cintra Adelia C O; Veronese Elen L G; Nomizo Auro; Franco João José; Arantes Eliane C; Giglio José Roberto; Sampaio Suely Vilela
Anticrotalic and antitumoral activities of gel filtration fractions of aqueous extract from Tabernaemontana catharinensis (Apocynaceae).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2004;137(1):19-27.
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2003: Soares Andreimar M; Giglio José R
Chemical modifications of phospholipases A2 from snake venoms: effects on catalytic and pharmacological properties.
Toxicon : official journal of the International Society on Toxinology 2003;42(8):855-68.
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2003: Magro Angelo J; Soares Andreimar M; Giglio José R; Fontes Marcos R M
Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights.
Biochemical and biophysical research communications 2003;311(3):713-20.
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2003: Ketelhut D F J; de Mello M Homem; Veronese E L G; Esmeraldino L E; Murakami M T; Arni R K; Giglio J R; Cintra A C O; Sampaio S V
Isolation, characterization and biological activity of acidic phospholipase A2 isoforms from Bothrops jararacussu snake venom.
Biochimie 2003;85(10):983-91.
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2003: Izidoro L F M; Rodrigues V M; Rodrigues R S; Ferro E V; Hamaguchi A; Giglio J R; Homsi-Brandeburgo M I
Neutralization of some hematological and hemostatic alterations induced by neuwiedase, a metalloproteinase isolated from Bothrops neuwiedi pauloensis snake venom, by the aqueous extract from Casearia mariquitensis (Flacourtiaceae).
Biochimie 2003;85(7):669-75.
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2003: Gonçalves Antonio A; Toyama Marcos H; Carneiro Everardo M; Marangoni Sergio; Arantes Eliana C; Giglio José R; Boschero Antonio C
Participation of Na(+) channels in the potentiation by Tityus serrulatus alpha-toxin TsTx-V of glucose-induced electrical activity and insulin secretion in rodent islet beta-cells.
Toxicon : official journal of the International Society on Toxinology 2003;41(8):1039-45.
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2003: Soares Andreimar M; Marcussi Silvana; Stábeli Rodrigo G; França Suzelei C; Giglio José R; Ward Richard J; Arantes Eliane C
Structural and functional analysis of BmjMIP, a phospholipase A2 myotoxin inhibitor protein from Bothrops moojeni snake plasma.
Biochemical and biophysical research communications 2003;302(2):193-200.
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2003: Brito Ana G; Soares Andreimar M; Homsi-Brandeburgo Maria I; Borges Márcia H; Giglio José R; Penha-Silva Nilson
Spectroscopic analysis of the stability of bothrops myotoxic phospholipases A2 to guanidine and urea denaturation.
Protein and peptide letters 2003;10(1):99-108.
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2002: Andrião-Escarso Sílvia H; Soares Andreimar M; Fontes Marcos R M; Fuly André L; Corrêa Fernando M A; Rosa José C; Greene Lewis J; Giglio José R
Structural and functional characterization of an acidic platelet aggregation inhibitor and hypotensive phospholipase A(2) from Bothrops jararacussu snake venom.
Biochemical pharmacology 2002;64(4):723-32.
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2002: Kashima Simone; Soares Andreimar M; Roberto Patrícia G; Pereira José O; Astolfi-Filho Spartaco; Cintra Adélia O; Fontes Marcos R M; Giglio José R; de Castro França Suzelei
cDNA sequence and molecular modeling of a nerve growth factor from Bothrops jararacussu venomous gland.
Biochimie 2002;84(7):675-80.
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2002: Soares Andreimar M; Oshima-Franco Yoko; Vieira Carlos A; Leite Gildo B; Fletcher Jeffrey E; Jiang M-S; Cintra Adelia C O; Giglio José R; Rodrigues-Simioni Léa
Mn(2+) ions reduce the enzymatic and pharmacological activities of bothropstoxin-I, a myotoxic Lys49 phospholipase A(2) homologue from Bothrops jararacussu snake venom.
The international journal of biochemistry & cell biology 2002;34(6):668-77.
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2002: Gambero Alessandra; Landucci Elen C T; Toyama Marcos H; Marangoni Sergio; Giglio Jose R; Nader Helena B; Dietrich Carl P; De Nucci Gilberto; Antunes Edson
Human neutrophil migration in vitro induced by secretory phospholipases A2: a role for cell surface glycosaminoglycans.
Biochemical pharmacology 2002;63(1):65-72.
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2001: Trento E P; Garcia O S; Rucavado A; França S C; Batalini C; Arantes E C; Giglio J R; Soares A M
Inhibitory properties of the anti-bothropic complex from Didelphis albiventris serum on toxic and pharmacological actions of metalloproteases and myotoxins from Bothrops asper venom.
Biochemical pharmacology 2001;62(11):1521-9.
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2001: Borges M H; Soares A M; Rodrigues V M; Oliveira F; Fransheschi A M; Rucavado A; Giglio J R; Homsi-Brandeburgo M I
Neutralization of proteases from Bothrops snake venoms by the aqueous extract from Casearia sylvestris (Flacourtiaceae).
Toxicon : official journal of the International Society on Toxinology 2001;39(12):1863-9.
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2001: Pessini A C; Takao T T; Cavalheiro E C; Vichnewski W; Sampaio S V; Giglio J R; Arantes E C
A hyaluronidase from Tityus serrulatus scorpion venom: isolation, characterization and inhibition by flavonoids.
Toxicon : official journal of the International Society on Toxinology 2001;39(10):1495-504.
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2001: Oshima-Franco Y; Leite G B; Silva G H; Cardoso D F; Hyslop S; Giglio J R; da Cruz-Höfling M A; Rodrigues-Simioni L
Neutralization of the pharmacological effects of bothropstoxin-I from Bothrops jararacussu (jararacuçu) venom by crotoxin antiserum and heparin.
Toxicon : official journal of the International Society on Toxinology 2001;39(10):1477-85.
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2001: Soares A M; Mancin A C; Cecchini A L; Arantes E C; França S C; Gutiérrez J M; Giglio J R
Effects of chemical modifications of crotoxin B, the phospholipase A(2) subunit of crotoxin from Crotalus durissus terrificus snake venom, on its enzymatic and pharmacological activities.
The international journal of biochemistry & cell biology 2001;33(9):877-88.
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2001: Cintra A C; Sampaio S V; Raghuvir A K; Giglio J R
Assignment of the disulfide bridges in bothropstoxin-I, a myonecrotic Lys49 PLA2 homolog from Bothrops jararacussu snake venom.
Journal of protein chemistry 2001;20(5):377-82.
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2001: Rodrigues V M; Soares A M; Andrião-Escarso S H; Franceschi A M; Rucavado A; Gutiérrez J M; Giglio J R
Pathological alterations induced by neuwiedase, a metalloproteinase isolated from Bothrops neuwiedi snake venom.
Biochimie 2001;83(6):471-9.
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2001: de Oliveira A H; Giglio J R; Andrião-Escarso S H; Ward R J
The effect of resonance energy homotransfer on the intrinsic tryptophan fluorescence emission of the bothropstoxin-I dimer.
Biochemical and biophysical research communications 2001;284(4):1011-5.
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2001: de Oliveira A H; Giglio J R; Andrião-Escarso S H; Ito A S; Ward R J
A pH-induced dissociation of the dimeric form of a lysine 49-phospholipase A2 abolishes Ca2+-independent membrane damaging activity.
Biochemistry 2001;40(23):6912-20.
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2001: Soares A M; Andrião-Escarso S H; Bortoleto R K; Rodrigues-Simioni L; Arni R K; Ward R J; Gutiérrez J M; Giglio J R
Dissociation of enzymatic and pharmacological properties of piratoxins-I and -III, two myotoxic phospholipases A2 from Bothrops pirajai snake venom.
Archives of biochemistry and biophysics 2001;387(2):188-96.
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2000: Oshima-Franco Y; Hyslop S; Cintra A C; Giglio J R; da Cruz-Höfling M A; Rodrigues-Simioni L
Neutralizing capacity of commercial bothropic antivenom against Bothrops jararacussu venom and bothropstoxin-I.
Muscle & nerve 2000;23(12):1832-9.
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2000: de Castro R C; Landucci E C; Toyama M H; Giglio J R; Marangoni S; De Nucci G; Antunes E
Leucocyte recruitment induced by type II phospholipases A(2) into the rat pleural cavity.
Toxicon : official journal of the International Society on Toxinology 2000;38(12):1773-85.
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2000: Borges M H; Soares A M; Rodrigues V M; Andrião-Escarso S H; Diniz H; Hamaguchi A; Quintero A; Lizano S; Gutiérrez J M; Giglio J R; Homsi-Brandeburgo M I
Effects of aqueous extract of Casearia sylvestris (Flacourtiaceae) on actions of snake and bee venoms and on activity of phospholipases A2.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2000;127(1):21-30.
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2000: Rodrigues V M; Soares A M; Guerra-Sá R; Rodrigues V; Fontes M R; Giglio J R
Structural and functional characterization of neuwiedase, a nonhemorrhagic fibrin(ogen)olytic metalloprotease from Bothrops neuwiedi snake venom.
Archives of biochemistry and biophysics 2000;381(2):213-24.
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2000: Andrião-Escarso S H; Soares A M; Rodrigues V M; Angulo Y; Díaz C; Lomonte B; Gutiérrez J M; Giglio J R
Myotoxic phospholipases A(2) in bothrops snake venoms: effect of chemical modifications on the enzymatic and pharmacological properties of bothropstoxins from Bothrops jararacussu.
Biochimie 2000;82(8):755-63.
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2000: Batina M de F; Cintra A C; Veronese E L; Lavrador M A; Giglio J R; Pereira P S; Dias D A; França S C; Sampaio S V
Inhibition of the lethal and myotoxic activities of Crotalus durissus terrificus venom by Tabernaemontana catharinensis: identification of one of the active components.
Planta medica 2000;66(5):424-8.
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2000: Soares A M; Guerra-Sá R; Borja-Oliveira C R; Rodrigues V M; Rodrigues-Simioni L; Rodrigues V; Fontes M R; Lomonte B; Gutiérrez J M; Giglio J R
Structural and functional characterization of BnSP-7, a Lys49 myotoxic phospholipase A(2) homologue from Bothrops neuwiedi pauloensis venom.
Archives of biochemistry and biophysics 2000;378(2):201-9.
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2000: Landucci E C; de Castro R C; Toyama M; Giglio J R; Marangoni S; De Nucci G; Antunes E
Inflammatory oedema induced by the lys-49 phospholipase A(2) homologue piratoxin-i in the rat and rabbit. Effect of polyanions and p-bromophenacyl bromide.
Biochemical pharmacology 2000;59(10):1289-94.
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2000: Toyama M H; Soares A M; Wen-Hwa L; Polikarpov I; Giglio J R; Marangoni S
Amino acid sequence of piratoxin-II, a myotoxic lys49 phospholipase A(2) homologue from Bothrops pirajai venom.
Biochimie 2000;82(3):245-50.
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2000: Soares A M; Andrião-Escarso S H; Angulo Y; Lomonte B; Gutiérrez J M; Marangoni S; Toyama M H; Arni R K; Giglio J R
Structural and functional characterization of myotoxin I, a Lys49 phospholipase A(2) homologue from Bothrops moojeni (Caissaca) snake venom.
Archives of biochemistry and biophysics 2000;373(1):7-15.
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1999: Fontes M R; Soares A M; Rodrigues V M; Fernandes A C; Da Silva R J; Giglio J R
Crystallization and preliminary X-ray diffraction analysis of a myotoxic phospholipase A(2) homologue from Bothrops neuwiedi pauloensis venom.
Biochimica et biophysica acta 1999;1432(2):393-5.
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1999: Oliveira F; Rodrigues V M; Borges M H; Soares A M; Hamaguchi A; Giglio J R; Homsi-Brandeburgo M I
Purification and partial characterization of a new proteolytic enzyme from the venom of Bothrops moojeni (CAISSACA).
Biochemistry and molecular biology international 1999;47(6):1069-77.
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1999: Homsi-Brandeburgo M I; Toyama M H; Marangoni S; Ward R J; Giglio J R; Hartley B S
The amino acid sequence of ribitol dehydrogenase-F, a mutant enzyme with improved xylitol dehydrogenase activity.
Journal of protein chemistry 1999;18(4):489-95.
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1999: Andrião-Escarso S H; Soares A M; Rodrigues V M; Mancin A C; Reis M L; Ballejo G; Giglio J R
Isolation and characterization of an arginine ester hydrolase from Bothrops jararacussu venom which induces contractions of the isolated rat uterus.
Biochemistry and molecular biology international 1999;47(4):699-706.
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1999: Novello J C; Arantes E C; Varanda W A; Oliveira B; Giglio J R; Marangoni S
TsTX-IV, a short chain four-disulfide-bridged neurotoxin from Tityus serrulatus venom which acts on Ca2+-activated K+ channels.
Toxicon : official journal of the International Society on Toxinology 1999;37(4):651-60.
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1998: Mancin A C; Soares A M; Andrião-Escarso S H; Faça V M; Greene L J; Zuccolotto S; Pelá I R; Giglio J R
The analgesic activity of crotamine, a neurotoxin from Crotalus durissus terrificus (South American rattlesnake) venom: a biochemical and pharmacological study.
Toxicon : official journal of the International Society on Toxinology 1998;36(12):1927-37.
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1998: Rodrigues V M; Soares A M; Mancin A C; Fontes M R; Homsi-Brandeburgo M I; Giglio J R
Geographic variations in the composition of myotoxins from Bothrops neuwiedi snake venoms: biochemical characterization and biological activity.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 1998;121(3):215-22.
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1998: Toyama M H; Soares A M; Vieira C A; Novello J C; Oliveira B; Giglio J R; Marangoni S
Amino acid sequence of piratoxin-I, a myotoxin from Bothrops pirajai snake venom, and its biological activity after alkylation with p-bromophenacyl bromide.
Journal of protein chemistry 1998;17(7):713-8.
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1998: Cogo J C; Prado-Franceschi J; Giglio J R; Corrado A P; Cruz-Höfling M A; Donato J L; Leite G B; Rodrigues-Simioni L
An unusual presynaptic action of Bothrops insularis snake venom mediated by phospholipase A2 fraction.
Toxicon : official journal of the International Society on Toxinology 1998;36(10):1323-32.
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1998: Pereira M F; Novello J C; Cintra A C; Giglio J R; Landucci E T; Oliveira B; Marangoni S
The amino acid sequence of bothropstoxin-II, an Asp-49 myotoxin from Bothrops jararacussu (Jararacucu) venom with low phospholipase A2 activity.
Journal of protein chemistry 1998;17(4):381-6.
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1998: Soares A M; Rodrigues V M; Homsi-Brandeburgo M I; Toyama M H; Lombardi F R; Arni R K; Giglio J R
A rapid procedure for the isolation of the Lys-49 myotoxin II from Bothrops moojeni (caissaca) venom: biochemical characterization, crystallization, myotoxic and edematogenic activity.
Toxicon : official journal of the International Society on Toxinology 1998;36(3):503-14.
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1998: da Silva Giotto M T; Garratt R C; Oliva G; Mascarenhas Y P; Giglio J R; Cintra A C; de Azevedo W F; Arni R K; Ward R J
Crystallographic and spectroscopic characterization of a molecular hinge: conformational changes in bothropstoxin I, a dimeric Lys49-phospholipase A2 homologue.
Proteins 1998;30(4):442-54.
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1998: Landucci E C; Castro R C; Pereira M F; Cintra A C; Giglio J R; Marangoni S; Oliveira B; Cirino G; Antunes E; De Nucci G
Mast cell degranulation induced by two phospholipase A2 homologues: dissociation between enzymatic and biological activities.
European journal of pharmacology 1998;343(2-3):257-63.
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1998: Teixeira C E; Bento A C; Lopes-Martins R A; Teixeira S A; von Eickestedt V; Muscará M N; Arantes E C; Giglio J R; Antunes E; de Nucci G
Effect of Tityus serrulatus scorpion venom on the rabbit isolated corpus cavernosum and the involvement of NANC nitrergic nerve fibres.
British journal of pharmacology 1998;123(3):435-42.
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1997: Soares A M; Rodrigues V M; Borges M H; Andrião-Escarso S H; Cunha O A; Homsi-Brandeburgo M I; Giglio J R
Inhibition of proteases, myotoxins and phospholipases A2 from Bothrops venoms by the heteromeric protein complex of Didelphis albiventris opossum serum.
Biochemistry and molecular biology international 1997;43(5):1091-9.
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1997: Mancin A C; Soares A M; Giglio C A; Andrião-Escarso S H; Vieira C A; Giglio J R
The histamine releasers crotamine, protamine and compound 48/80 activate specific proteases and phospholipases A2.
Biochemistry and molecular biology international 1997;42(6):1171-7.
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1997: Corrêa M M; Sampaio S V; Lopes R A; Mancuso L C; Cunha O A; Franco J J; Giglio J R
Biochemical and histopathological alterations induced in rats by Tityus serrulatus scorpion venom and its major neurotoxin tityustoxin-I.
Toxicon : official journal of the International Society on Toxinology 1997;35(7):1053-67.
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1997: Andrião-Escarso S H; Sampaio S V; Cunha O A; Marangoni S; Oliveira B; Giglio J R
Isolation and characterization of a new clotting factor from Bothrops jararacussu (jararacuçu) venom.
Toxicon : official journal of the International Society on Toxinology 1997;35(7):1043-52.
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1997: Sampaio S V; Coutinho-Netto J; Arantes E C; Toyama M H; Novello J C; Giglio J R
TsTX-VII, a new toxin from Tityus serrulatus scorpion venom able to induce the release of neurotransmitters from rat brain synaptosomes not blocked by tetrodotoxin.
Biochemistry and molecular biology international 1997;41(6):1255-63.
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1996: Rego E; Bento A C; Lopes-Martins R A; Antunes E; Novello J C; Marangoni S; Giglio J R; Oliveira B; De Nucci G
Isolation and partial characterization of a polypeptide from Phoneutria nigriventer spider venom that relaxes rabbit corpus cavernosum in vitro.
Toxicon : official journal of the International Society on Toxinology 1996;34(10):1141-7.
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1996: Sampaio S V; Coutinho-Netto J; Arantes E C; Marangoni S; Oliveira B; Giglio J R
Isolation of toxin TsTX-VI from Tityus serrulatus scorpion venom. Effects on the release of neurotransmitters from synaptosomes.
Biochemistry and molecular biology international 1996;39(4):729-40.
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1996: Bortoleto R K; Ward R J; Giglio J R; Cintra A C; Arni R K
Crystallization of bothropstoxin II isolated from the venom of Bothrops jararacussu.
Toxicon : official journal of the International Society on Toxinology 1996;34(5):614-7.
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1995: Toyama M H; Mancuso L C; Giglio J R; Novello J C; Oliveira B; Marangoni S
A quick procedure for the isolation of dimeric piratoxins-I and II, two myotoxins from Bothrops pirajai snake venom. N-terminal sequencing.
Biochemistry and molecular biology international 1995;37(6):1047-55.
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1995: Rodrigues-Simioni L; Prado-Franceschi J; Cintra A C; Giglio J R; Jiang M S; Fletcher J E
No role for enzymatic activity or dantrolene-sensitive Ca2+ stores in the muscular effects of bothropstoxin, a Lys49 phospholipase A2 myotoxin.
Toxicon : official journal of the International Society on Toxinology 1995;33(11):1479-89.
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1995: Mancuso L C; Correa M M; Vieira C A; Cunha O A; Lachat J J; de Araujo H S; Ownby C L; Giglio J R
Fractionation of Bothrops pirajai snake venom: isolation and characterization of piratoxin-I, a new myotoxic protein.
Toxicon : official journal of the International Society on Toxinology 1995;33(5):615-26.
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1995: Marangoni S; Toyama M H; Arantes E C; Giglio J R; da Silva C A; Carneiro E M; Gonçalves A A; Oliveira B
Amino acid sequence of TsTX-V, an alpha-toxin from Tityus serrulatus scorpion venom, and its effect on K+ permeability of beta-cells from isolated rat islets of Langerhans.
Biochimica et biophysica acta 1995;1243(3):309-14.
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1995: Arni R K; Ward R J; Cintra A C; Giglio J R
Crystallization and preliminary diffraction data of bothropstoxin I isolated from the venom of Bothrops jararacussu.
Toxicon : official journal of the International Society on Toxinology 1995;33(3):383-6.
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1995: Bento A C; Rego E; Pedroso-Mariani S R; Mancuso L C; Giglio J R; Novello J C; Marangoni S; Caracelli I; Oliveira B; Antunes E
Isolation of a polypeptide from Phoneutria nigriventer spider venom responsible for the increased vascular permeability in rabbit skin.
Toxicon : official journal of the International Society on Toxinology 1995;33(2):171-8.
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1994: Arantes E C; Riccioppo Neto F; Sampaio S V; Vieira C A; Giglio J R
Isolation and characterization of TsTX-V, a new neurotoxin from Tityus serrulatus scorpion venom which delays the inactivation of Na+ channels.
Biochimica et biophysica acta 1994;1199(1):69-75.
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1993: Antunes E; Marangoni R A; Giglio J R; Brain S D; de Nucci G
Activation of tissue kallikrein-kininogen-kinin system in rabbit skin by a fraction isolated from Phoneutria nigriventer (armed spider) venom.
Toxicon : official journal of the International Society on Toxinology 1993;31(11):1385-91.
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1993: Bento A C; Novello J C; Marangoni S; Antunes E; Giglio J R; Oliveira B; de Nucci G
Identification of a new vascular smooth muscle contracting polypeptide in Phoneutria nigriventer spider venom.
Biochemical pharmacology 1993;46(6):1092-5.
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1993: Marangoni S; Borges N C; Marangoni R A; Antunes E; Vieira C A; Novello J C; Domont G B; Giglio J R; Oliveira B; de Nucci G
Biochemical characterization of a vascular smooth muscle contracting polypeptide purified from Phoneutria nigriventer (armed spider) venom.
Toxicon : official journal of the International Society on Toxinology 1993;31(4):377-84.
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1993: Melo P A; Homsi-Brandeburgo M I; Giglio J R; Suarez-Kurtz G
Antagonism of the myotoxic effects of Bothrops jararacussu venom and bothropstoxin by polyanions.
Toxicon : official journal of the International Society on Toxinology 1993;31(3):285-91.
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1993: Cintra A C; Marangoni S; Oliveira B; Giglio J R
Bothropstoxin-I: amino acid sequence and function.
Journal of protein chemistry 1993;12(1):57-64.
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1992: Heluany N F; Homsi-Brandeburgo M I; Giglio J R; Prado-Franceschi J; Rodrigues-Simioni L
Effects induced by bothropstoxin, a component from Bothrops jararacussu snake venom, on mouse and chick muscle preparations.
Toxicon : official journal of the International Society on Toxinology 1992;30(10):1203-10.
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1992: Arantes E C; Sampaio S V; Vieira C A; Giglio J R
What is tityustoxin?
Toxicon : official journal of the International Society on Toxinology 1992;30(7):786-9.
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1991: Gutiérrez J M; Núñez J; Díaz C; Cintra A C; Homsi-Brandeburgo M I; Giglio J R
Skeletal muscle degeneration and regeneration after injection of bothropstoxin-II, a phospholipase A2 isolated from the venom of the snake Bothrops jararacussu.
Experimental and molecular pathology 1991;55(3):217-29.
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1991: de Mesquita L C; Selistre H S; Giglio J R
The hypotensive activity of Crotalus atrox (western diamondback rattlesnake) venom: identification of its origin.
The American journal of tropical medicine and hygiene 1991;44(3):345-53.
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1991: Sampaio S V; Arantes E C; Prado W A; Riccioppo Neto F; Giglio J R
Further characterization of toxins T1IV (TsTX-III) and T2IV from Tityus serrulatus scorpion venom.
Toxicon : official journal of the International Society on Toxinology 1991;29(6):663-72.
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1990: Marangoni S; Ghiso J; Sampaio S V; Arantes E C; Giglio J R; Oliveira B; Frangione B
The complete amino acid sequence of toxin TsTX-VI isolated from the venom of the scorpion Tityus serrulatus.
Journal of protein chemistry 1990;9(5):595-601.
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1990: Teno A M; Vieira C A; Santoro M M; Neves A G; Giglio J R
Interchain disulfide bonds in crotamine self-association.
Journal of biochemistry 1990;107(6):821-5.
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1990: Cintra A C; Vieira C A; Giglio J R
Primary structure and biological activity of bradykinin potentiating peptides from Bothrops insularis snake venom.
Journal of protein chemistry 1990;9(2):221-7.
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1990: Selistre H S; Queiroz L S; Cunha O A; De Souza G E; Giglio J R
Isolation and characterization of hemorrhagic, myonecrotic and edema-inducing toxins from Bothrops insularis (jararaca ilhoa) snake venom.
Toxicon : official journal of the International Society on Toxinology 1990;28(3):261-73.
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1990: Borges A; Arantes E C; Giglio J R
Isolation and characterization of toxic proteins from the venom of the Venezuelan scorpion Tityus discrepans (Karsch).
Toxicon : official journal of the International Society on Toxinology 1990;28(9):1011-7.
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1989: Arantes E C; Prado W A; Sampaio S V; Giglio J R
A simplified procedure for the fractionation of Tityus serrulatus venom: isolation and partial characterization of TsTX-IV, a new neurotoxin.
Toxicon : official journal of the International Society on Toxinology 1989;27(8):907-16.
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1989: Oliveira M J; Fontana M D; Giglio J R; Sampaio S V; Corrado A P; Prado W A
Effects of the venom of the Brazilian scorpion Tityus serrulatus and two of its fractions on the isolated diaphragm of the rat.
General pharmacology 1989;20(2):205-10.
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1989: Mello L E; Prado-Franceschi J; Giglio J R; Cavalheiro E A
Convulxin does not induce convulsions when injected into the rat dorsal hippocampus.
Acta physiologica et pharmacologica latinoamericana : organo de la Asociación Latinoamericana de Ciencias Fisiológicas y de la Asociación Latinoamericana de Farmacología 1989;39(4):353-8.
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1988: Homsi-Brandeburgo M I; Queiroz L S; Santo-Neto H; Rodrigues-Simioni L; Giglio J R
Fractionation of Bothrops jararacussu snake venom: partial chemical characterization and biological activity of bothropstoxin.
Toxicon : official journal of the International Society on Toxinology 1988;26(7):615-27.
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1987: Arêas E P; Giglio J R; Arantes E C; Kawano Y
Raman and infrared spectra of toxin gamma from the venom of the scorpion Tityus serrulatus.
Biochimica et biophysica acta 1987;915(2):292-8.
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1987: Selistre H S; Giglio J R
Isolation and characterization of a thrombin-like enzyme from the venom of the snake Bothrops insularis (jararaca ilhoa).
Toxicon : official journal of the International Society on Toxinology 1987;25(11):1135-44.
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1986: Jonas P; Vogel W; Arantes E C; Giglio J R
Toxin gamma of the scorpion Tityus serrulatus modifies both activation and inactivation of sodium permeability of nerve membrane.
Pflügers Archiv : European journal of physiology 1986;407(1):92-9.
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1984: Barhanin J; Ildefonse M; Rougier O; Sampaio S V; Giglio J R; Lazdunski M
Tityus gamma toxin, a high affinity effector of the Na+ channel in muscle, with a selectivity for channels in the surface membrane.
Pflügers Archiv : European journal of physiology 1984;400(1):22-7.
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1983: Sampaio S V; Laure C J; Giglio J R
Isolation and characterization of toxic proteins from the venom of the Brazilian scorpion Tityus serrulatus.
Toxicon : official journal of the International Society on Toxinology 1983;21(2):265-77.
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1982: Barhanin J; Giglio J R; Léopold P; Schmid A; Sampaio S V; Lazdunski M
Tityus serrulatus venom contains two classes of toxins. Tityus gamma toxin is a new tool with a very high affinity for studying the Na+ channel.
The Journal of biological chemistry 1982;257(21):12553-8.
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