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Adalgeir Arason

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Iceland

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Göran Jönsson; Niklas Loman; Kristina Lövgren; Linda Magnusson; Per Malmström; Heli Nevanlinna; Håkan Olsson; Camilla Persson; Markus Ringnér; Lao H Saal; Johan Staaf; Johan Vallon-Christersson; Rainer Fagerholm; Mårten Fernö; Dorthe Grabau; Sofia K Gruvberger-Saal; Cecilia Hegardt; Päivi Heikkilä; Karolina Holm; Oskar T Johannsson; Ellinor Johnsson; Bjarni A Agnarsson; Adalgeir Arason; Rosa B Barkardottir; Åke Borg
The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.
Karolina Holm; Göran Jönsson; Linda Magnusson; Markus Ringnér; Johan Staaf; Johan Vallon-Christersson; Adalgeir Arason; Rosa B Barkardottir; Haukur Gunnarsson; Cecilia Hegardt; Ake Borg
Characterisation of amplification patterns and target genes at chromosome 11q13 in CCND1-amplified sporadic and familial breast tumours.
Yael Laitman; Lesley McGuffog; Katherine L Nathanson; Susan L Neuhausen; Heli Nevanlinna; Kenneth Offit; Susan Peock; Paolo Peterlongo; Paolo Radice; Johanna Rantala; Rita K Schmutzler; Olga M Sinilnikova; Barbara Wappenschmidt; Ido Wolf; Antonis C Antoniou; Adalgeir Arason; Maria Adelaide Caligo; Xiaoqing Chen; Georgia Chenevix-Trench; Fergus Couch; Douglas F Easton; Patricia Ganz; Andrew K Godwin; Sue Healey; Frans B L Hogervorst; Claudine Isaacs; Tomas Kirchhoff; Karoline B Kuchenbaecker; Eitan Friedman
The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers.

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All Publications

2012: Göran Jönsson; Niklas Loman; Kristina Lövgren; Linda Magnusson; Per Malmström; Heli Nevanlinna; Håkan Olsson; Camilla Persson; Markus Ringnér; Lao H Saal; Johan Staaf; Johan Vallon-Christersson; Rainer Fagerholm; Mårten Fernö; Dorthe Grabau; Sofia K Gruvberger-Saal; Cecilia Hegardt; Päivi Heikkilä; Karolina Holm; Oskar T Johannsson; Ellinor Johnsson; Bjarni A Agnarsson; Adalgeir Arason; Rosa B Barkardottir; Åke Borg
The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.
Cancer research 2012;72(16):4028-36.
2012: Karolina Holm; Göran Jönsson; Linda Magnusson; Markus Ringnér; Johan Staaf; Johan Vallon-Christersson; Adalgeir Arason; Rosa B Barkardottir; Haukur Gunnarsson; Cecilia Hegardt; Ake Borg
Characterisation of amplification patterns and target genes at chromosome 11q13 in CCND1-amplified sporadic and familial breast tumours.
Breast cancer research and treatment 2012;133(2):583-94.
2012: Yael Laitman; Lesley McGuffog; Katherine L Nathanson; Susan L Neuhausen; Heli Nevanlinna; Kenneth Offit; Susan Peock; Paolo Peterlongo; Paolo Radice; Johanna Rantala; Rita K Schmutzler; Olga M Sinilnikova; Barbara Wappenschmidt; Ido Wolf; Antonis C Antoniou; Adalgeir Arason; Maria Adelaide Caligo; Xiaoqing Chen; Georgia Chenevix-Trench; Fergus Couch; Douglas F Easton; Patricia Ganz; Andrew K Godwin; Sue Healey; Frans B L Hogervorst; Claudine Isaacs; Tomas Kirchhoff; Karoline B Kuchenbaecker; Eitan Friedman
The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers.
Breast cancer research and treatment 2012;132(3):1119-26.
2012: Eydis Th Gudmundsdottir; Haukur Gunnarsson; Oskar T Johannsson; Bjarni A Agnarsson; Laufey T Amundadottir; Adalgeir Arason; Rosa B Barkardottir; Inga Reynisdottir
The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients.
BMC cancer 2012;12():621.
2010: Johan Staaf; Markus Ringnér; Johan Vallon-Christersson; Göran Jönsson; Pär-Ola Bendahl; Karolina Holm; Adalgeir Arason; Haukur Gunnarsson; Cecilia Hegardt; Bjarni A Agnarsson; Lena Luts; Dorthe Grabau; Mårten Fernö; Per-Olof Malmström; Oskar Th Johannsson; Niklas Loman; Rosa B Barkardottir; Ake Borg
Identification of subtypes in human epidermal growth factor receptor 2--positive breast cancer reveals a gene signature prognostic of outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(11):1813-20.
2010: Adalgeir Arason; Haukur Gunnarsson; Gudrun Johannesdottir; Kristjan Jonasson; Pär-Ola Bendahl; Elizabeth M Gillanders; Bjarni A Agnarsson; Göran Jönsson; Katri Pylkäs; Aki Mustonen; Tuomas Heikkinen; Kristiina Aittomäki; Carl Blomqvist; Beatrice Melin; Oskar T H Johannsson; Pål Møller; Robert Winqvist; Heli Nevanlinna; Ake Borg; Rosa B Barkardottir
Genome-wide search for breast cancer linkage in large Icelandic non-BRCA1/2 families.
Breast cancer research : BCR 2010;12(4):R50.
2010: Göran Jönsson; Johan Staaf; Johan Vallon-Christersson; Markus Ringnér; Karolina Holm; Cecilia Hegardt; Haukur Gunnarsson; Rainer Fagerholm; Carina Strand; Bjarni A Agnarsson; Outi Kilpivaara; Lena Luts; Päivi Heikkilä; Kristiina Aittomäki; Carl Blomqvist; Niklas Loman; Per Malmström; Håkan Olsson; Oskar Th Johannsson; Adalgeir Arason; Heli Nevanlinna; Rosa B Barkardottir; Ake Borg
Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics.
Breast cancer research : BCR 2010;12(3):R42.
2010: Johan Staaf; Göran Jönsson; Markus Ringnér; Johan Vallon-Christersson; Dorthe Grabau; Adalgeir Arason; Haukur Gunnarsson; Bjarni A Agnarsson; Per-Olof Malmström; Oskar T Johannsson; Niklas Loman; Rosa B Barkardottir; Ake Borg
High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer.
Breast cancer research : BCR 2010;12(3):R25.
2008: Haukur Gunnarsson; Adalgeir Arason; Elizabeth M Gillanders; Bjarni A Agnarsson; Gudrun Johannesdottir; Oskar Th Johannsson; Rosa B Barkardottir
Evidence against PALB2 involvement in Icelandic breast cancer susceptibility.
Journal of negative results in biomedicine 2008;7():5.
2006: Sanna-Maria Karppinen; Rosa B Barkardottir; K Backenhorn; T Sydenham; Kirsi Syrjäkoski; Johanna Schleutker; Tarja Ikonen; Katri Pylkäs; Katrin Rapakko; Hannele Erkko; Gudrun Johannesdottir; Anne-Marie Gerdes; Mads Thomassen; Bjarni A Agnarsson; M Grip; Anne Kallioniemi; Juha Kere; Lauri A Aaltonen; Adalgeir Arason; P Møller; Torben A Kruse; Ake Borg; Robert Winqvist
Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies.
Journal of medical genetics 2006;43(11):856-62.
2006: Hrefna Kristin Johannsdottir; Goran Jonsson; Gudrun Johannesdottir; Bjarni A Agnarsson; Hannaleena Eerola; Adalgeir Arason; Paivi Heikkila; Valgardur Egilsson; Hakan Olsson; Oskar T Johannsson; Heli Nevanlinna; Ake Borg; Rosa B Barkardottir
Chromosome 5 imbalance mapping in breast tumors from BRCA1 and BRCA2 mutation carriers and sporadic breast tumors.
International journal of cancer. Journal international du cancer 2006;119(5):1052-60.
2004: Hrefna Kristin Johannsdottir; Gudrun Johannesdottir; Bjarni A Agnarsson; Hannaleena Eerola; Adalgeir Arason; Oskar T Johannsson; Päivi Heikkilä; Valgardur Egilsson; Hakan Olsson; Ake Borg; Heli Nevanlinna; Rosa B Barkardottir
Deletions on chromosome 4 in sporadic and BRCA mutated tumors and association with pathological variables.
Anticancer research 2004;24(5A):2681-7.
2002: Hrafn Tulinius; Gudridur H Olafsdottir; Helgi Sigvaldason; Adalgeir Arason; Rosa B Barkardottir; Valgardur Egilsson; Helga M Ogmundsdottir; Laufey Tryggvadottir; Sigfridur Gudlaugsdottir; Jorunn E Eyfjord
The effect of a single BRCA2 mutation on cancer in Iceland.
Journal of medical genetics 2002;39(7):457-62.
2002: Ester Rozenblum; Pia Vahteristo; Therese Sandberg; Jon Thor Bergthorsson; Kirsi Syrjakoski; Don Weaver; Karin Haraldsson; Hrefna Kristin Johannsdottir; Paula Vehmanen; Savita Nigam; Natalie Golberger; Christiane Robbins; Evgenia Pak; Amalia Dutra; Elizabeth Gillander; Dietrich A Stephan; Joan E Bailey-Wilson; Suh-Hang Hank Juo; Tommi Kainu; Adalgeir Arason; Rosa B Barkardottir; Heli Nevanlinna; Ake Borg; Olli Kallioniemi
A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes.
Human genetics 2002;110(2):111-21.
2002: Sigurdur Ingvarsson; Bjarnveig I Sigbjornsdottir; Chen Huiping; Sigridur H Hafsteinsdottir; Gisli Ragnarsson; Rosa B Barkardottir; Adalgeir Arason; Valgardur Egilsson; Jon Thor Bergthorsson
Mutation analysis of the CHK2 gene in breast carcinoma and other cancers.
Breast cancer research : BCR 2002;4(3):R4.
2001: Rosa B Barkardottir; Laura Sarantaus; Adalgeir Arason; Paula Vehmanen; P O Bendahl; Tommi Kainu; Kirsi Syrjäkoski; Ralf Krahe; Pia Huusko; Seppo Pyrhönen; Kaija Holli; Olli Kallioniemi; Valgardur Egilsson; Juha Kere; Heli Nevanlinna
Haplotype analysis in Icelandic and Finnish BRCA2 999del5 breast cancer families.
European journal of human genetics : EJHG 2001;9(10):773-9.
2000: Jon Thor Bergthorsson; Gudrun Johannesdottir; Adalgeir Arason; K R Benediktsdottir; Bjarni A Agnarsson; Joan E Bailey-Wilson; Elizabeth M Gillanders; J Smith; Jeffrey M. Trent; Rosa B Barkardottir
Analysis of HPC1, HPCX, and PCaP in Icelandic hereditary prostate cancer.
Human genetics 2000;107(4):372-5.
1999: Chen Huiping; JT Johannsdottir; Adalgeir Arason; Gudridur H Olafsdottir; G Eiriksdottir; Valgardur Egilsson; Sigurdur Ingvarsson
Replication error in human breast cancer: comparison with clinical variables and family history of cancer.
Oncology reports 1999;6(1):117-22.
1998: Adalgeir Arason; A Jonasdottir; Rosa B Barkardottir; Jon Thor Bergthorsson; MD Teare; Douglas F Easton; Valgardur Egilsson
A population study of mutations and LOH at breast cancer gene loci in tumours from sister pairs: two recurrent mutations seem to account for all BRCA1/BRCA2 linked breast cancer in Iceland.
Journal of medical genetics 1998;35(6):446-9.
1998: D Ford; Douglas F Easton; Michael Stratton; Steven A Narod; David E Goldgar; Peter Devilee; Tim BISHOP; B Weber; G Lenoir; Jenny Chang-Claude; H Sobol; MD Teare; Jeffery Struewing; Adalgeir Arason; Siegfried Scherneck; Julian Peto; T R Rebbeck; P Tonin; Susan L Neuhausen; Rosa B Barkardottir; Jorunn E Eyfjord; H Lynch; Bruce A J Ponder; Simon A Gayther; M Zelada-Hedman
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.
American journal of human genetics 1998;62(3):676-89.
1998: Jon Thor Bergthorsson; JT Johannsdottir; A Jonasdottir; G Eiriksdottir; Valgardur Egilsson; Sigurdur Ingvarsson; Rosa B Barkardottir; Adalgeir Arason
Chromosome imbalance at the 3p14 region in human breast tumours: high frequency in patients with inherited predisposition due to BRCA2.
European journal of cancer (Oxford, England : 1990) 1998;34(1):142-7.
1998: Jon Thor Bergthorsson; A Jonasdottir; Gudrun Johannesdottir; Adalgeir Arason; Valgardur Egilsson; Simon A Gayther; Ake Borg; S Hakanson; Sigurdur Ingvarsson; Rosa B Barkardottir
Identification of a novel splice-site mutation of the BRCA1 gene in two breast cancer families: screening reveals low frequency in Icelandic breast cancer patients.
Human mutation 1998;Suppl 1():S195-7.
1996: Gudrun Johannesdottir; Julius Gudmundsson; Jon Thor Bergthorsson; Adalgeir Arason; Bjarni A Agnarsson; G Eiriksdottir; Oskar T Johannsson; Ake Borg; Sigurdur Ingvarsson; Douglas F Easton; Valgardur Egilsson; Rosa B Barkardottir
High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients.
Cancer research 1996;56(16):3663-5.
1996: Julius Gudmundsson; Gudrun Johannesdottir; Adalgeir Arason; Jon Thor Bergthorsson; Sigurdur Ingvarsson; Valgardur Egilsson; Rosa B Barkardottir
Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and segregation of a common BRCA2 haplotype.
American journal of human genetics 1996;58(4):749-56.
1995: Julius Gudmundsson; Gudrun Johannesdottir; Jon Thor Bergthorsson; Adalgeir Arason; Sigurdur Ingvarsson; Valgardur Egilsson; Rosa B Barkardottir
Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-q13.
Cancer research 1995;55(21):4830-2.
1995: Jon Thor Bergthorsson; G Eiriksdottir; Rosa B Barkardottir; Valgardur Egilsson; Adalgeir Arason; Sigurdur Ingvarsson
Linkage analysis and allelic imbalance in human breast cancer kindreds using microsatellite markers from the short arm of chromosome 3.
Human genetics 1995;96(4):437-43.
1995: Julius Gudmundsson; Rosa B Barkardottir; G Eiriksdottir; T Baldursson; Adalgeir Arason; Valgardur Egilsson; Sigurdur Ingvarsson
Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations.
British journal of cancer 1995;72(3):696-701.
1995: R S Cornelis; Susan L Neuhausen; O Johansson; Adalgeir Arason; D Kelsell; Bruce A J Ponder; Patricia N Tonin; U Hamann; A Lindblom; P Lalle
High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCAl-linked families. The Breast Cancer Linkage Consortium.
Genes, chromosomes & cancer 1995;13(3):203-10.
1995: Jon Thor Bergthorsson; Valgardur Egilsson; Julius Gudmundsson; Adalgeir Arason; Sigurdur Ingvarsson
Identification of a breast tumor with microsatellite instability in a potential carrier of the hereditary non-polyposis colon cancer trait.
Clinical genetics 1995;47(6):305-10.
1995: R B Barkardóttir; Adalgeir Arason; Valgardur Egilsson; Julius Gudmundsson; A Jónasdóttir; G Jóhannesdóttir
Chromosome 17q-linkage seems to be infrequent in Icelandic families at risk of breast cancer.
Acta oncologica (Stockholm, Sweden) 1995;34(5):657-62.
1993: Adalgeir Arason; R B Barkardóttir; Valgardur Egilsson
Linkage analysis of chromosome 17q markers and breast-ovarian cancer in Icelandic families, and possible relationship to prostatic cancer.
American journal of human genetics 1993;52(4):711-7.
1989: R B Barkardóttir; O T Jóhannsson; Adalgeir Arason; V Gudnason; Valgardur Egilsson
Polymorphism of the c-Ha-ras-1 proto-oncogene in sporadic and familial breast cancer.
International journal of cancer. Journal international du cancer 1989;44(2):251-5.