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Gary Gilkeson

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Eiji Suzuki; Dennis K Watson; Sarah Williams; Gary S Gilkeson; Eva Karam; Xian-Kui John Zhang
Fli-1 transcription factor affects glomerulonephritis development by regulating expression of monocyte chemoattractant protein-1 in endothelial cells in the kidney.
Fei Gu; Ivan D Molano; Philip Ruiz; Lingyun Sun; Gary S Gilkeson
Differential effect of allogeneic versus syngeneic mesenchymal stem cell transplantation in MRL/lpr and (NZB/NZW)F1 mice.
Melissa A Cunningham; Jackie G EuDaly; Osama Naga; Jennifer L Scott; Gary S Gilkeson
Estrogen receptor alpha modulates Toll-like receptor signaling in murine lupus.

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2012: Eiji Suzuki; Dennis K Watson; Sarah Williams; Gary S Gilkeson; Eva Karam; Xian-Kui John Zhang
Fli-1 transcription factor affects glomerulonephritis development by regulating expression of monocyte chemoattractant protein-1 in endothelial cells in the kidney.
Clinical immunology (Orlando, Fla.) 2012;145(3):201-8.
2012: Fei Gu; Ivan D Molano; Philip Ruiz; Lingyun Sun; Gary S Gilkeson
Differential effect of allogeneic versus syngeneic mesenchymal stem cell transplantation in MRL/lpr and (NZB/NZW)F1 mice.
Clinical immunology (Orlando, Fla.) 2012;145(2):142-52.
2012: Melissa A Cunningham; Jackie G EuDaly; Osama Naga; Jennifer L Scott; Gary S Gilkeson
Estrogen receptor alpha modulates Toll-like receptor signaling in murine lupus.
Clinical immunology (Orlando, Fla.) 2012;144(1):1-12.
2012: Timothy B Niewold; Michelle Petri; Rosalind Ramsey-Goldman; John D Reveille; Kenaz Thomas; Mohammed Tikly; Timothy J Vyse; Daniel Walker; Andrew K Wong; Graciela S Alarcón; Marta E Alarcón-Riquelme; Mary Crow; Jeffrey C Edberg; Beverly S Franek; Jacqueline M Frost; Patrick M Gaffney; Gary S Gilkeson; Judith A James; Diane L Kamen; Stan Kamp; Silvia N Kariuki; Kenneth M Kaufman; Jennifer A Kelly; Robert P Kimberly; Akaash A Kumar; Joan T Merrill; Kathy L Moser; John B Harley
IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus.
Annals of the rheumatic diseases 2012;71(3):463-8.
2012: Yu Tang; Xiaofeng Zeng; Huayong Zhang; Gary S Gilkeson; Zhifeng Gu; Yayi Hou; Liwei Lu; Xiaolei Ma; Lingyun Sun
Gene expression profile reveals abnormalities of multiple signaling pathways in mesenchymal stem cell derived from patients with systemic lupus erythematosus.
Clinical & developmental immunology 2012;2012():826182.
2011: Elena Sánchez; Betty P Tsao; Luis M Vilá; Timothy J Vyse; Graciela S Alarcón; Marta E Alarcón-Riquelme; Elizabeth E Brown; Mary E Comeau; Jeffrey C Edberg; Barry I Freedman; Patrick M Gaffney; Gary S Gilkeson; John B Harley; Chaim O Jacob; Judith A James; Diane L Kamen; Kenneth M Kaufman; Jennifer A Kelly; Robert P Kimberly; Carl D Langefeld; Joan T Merrill; Timothy B Niewold; Michelle Petri; Rosalind Ramsey-Goldman; John D Reveille; Bruce C Richardson; Amr H Sawalha
Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.
Arthritis and rheumatism 2011;63(11):3493-501.
2011: Hideharu Sekine; Gary S Gilkeson; Phillip Ruiz; Stephen Tomlinson
The dual role of complement in the progression of renal disease in NZB/W F(1) mice and alternative pathway inhibition.
Molecular immunology 2011;49(1-2):317-23.
2011: Travis Hughes; Xana Kim-Howard; Jennifer A Kelly; Kenneth M Kaufman; Carl D Langefeld; Julie Ziegler; Elena Sanchez; Robert P Kimberly; Jeffrey C Edberg; Rosalind Ramsey-Goldman; Michelle Petri; John D Reveille; Javier Martín; Elizabeth E Brown; Luis M Vilá; Graciela S Alarcón; Judith A James; Gary S Gilkeson; Kathy L Moser; Patrick M Gaffney; Joan T Merrill; Timothy J Vyse; Marta E Alarcón-Riquelme; Swapan K Nath; John B Harley; Amr H Sawalha
Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
Arthritis and rheumatism 2011;63(6):1689-97.
2011: Hideharu Sekine; Ting Ting Hsieh Kinser; Fei Qiao; Efrain Martinez; Emily Paulling; Phillip Ruiz; Gary S Gilkeson; Stephen Tomlinson
The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice.
Arthritis and rheumatism 2011;63(4):1076-85.
2011: Tamara Nowling; Gary S Gilkeson
Mechanisms of tissue injury in lupus nephritis.
Arthritis research & therapy 2011;13(6):250.
2011: Ryan Webb; Jennifer A Kelly; Emily Somers; Travis Hughes; Kenneth M Kaufman; Elena Sanchez; Swapan K Nath; Gail R Bruner; Marta E Alarcón-Riquelme; Gary S Gilkeson; Diane L Kamen; Bruce C Richardson; John B Harley; Amr H Sawalha
Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.
Annals of the rheumatic diseases 2011;70(1):151-6.
2010: C G Parks; R E Biagini; G S Cooper; Gary S Gilkeson; M A Dooley
Total serum IgE levels in systemic lupus erythematosus and associations with childhood onset allergies.
Lupus 2010;19(14):1614-22.
2010: Omar Moussa; Amanda C Larue; Romeo S Abangan; Christopher R Williams; Xian-Kui John Zhang; Masahiro Masuya; Yong Z Gong; Demetri D Spyropoulos; Makio Ogawa; Gary S Gilkeson; Dennis Watson
Thrombocytopenia in mice lacking the carboxy-terminal regulatory domain of the Ets transcription factor Fli1.
Molecular and cellular biology 2010;30(21):5194-206.
2010: J Mathenia; E Reyes-Cortes; S Williams; Ivan D Molano; Phillip Ruiz; Dennis Watson; Gary S Gilkeson; Xian-Kui John Zhang
Impact of Fli-1 transcription factor on autoantibody and lupus nephritis in NZM2410 mice.
Clinical and experimental immunology 2010;162(2):362-71.
2010: Jun Liang; Huayong Zhang; Bingzhu Hua; Hong Wang; Liwei Lu; Songtao Shi; Yayi Hou; Xiaofeng Zeng; Gary S Gilkeson; Lingyun Sun
Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study.
Annals of the rheumatic diseases 2010;69(8):1423-9.
2010: Xana Kim-Howard; Amit K Maiti; Juan-Manuel Anaya; Gail R Bruner; Elizabeth E Brown; Joan T Merrill; Jeffrey C Edberg; Michelle Petri; John D Reveille; Rosalind Ramsey-Goldman; Graciela S Alarcon; Timothy J Vyse; Gary S Gilkeson; Robert P Kimberly; Judith A James; Guthridge Joel; John B Harley; Swapan K Nath
ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry.
Annals of the rheumatic diseases 2010;69(7):1329-32.
2010: Ivan D Molano; J Mathenia; Phillip Ruiz; Gary S Gilkeson; Xian-Kui John Zhang
Decreased expression of Fli-1 in bone marrow-derived haematopoietic cells significantly affects disease development in Murphy Roths Large/lymphoproliferation (MRL/lpr) mice.
Clinical and experimental immunology 2010;160(2):275-82.
2010: Erin E Morris; May Y Amria; Emily Kistner-Griffin; John L Svenson; Diane L Kamen; Gary S Gilkeson; Tamara Nowling
A GA microsatellite in the Fli1 promoter modulates gene expression and is associated with systemic lupus erythematosus patients without nephritis.
Arthritis research & therapy 2010;12(6):R212.
2010: Baerbel Rohrer; Qin Long; Beth Coughlin; Brandon Renner; Yuxiang Huang; Kannan Kunchithapautham; Viviana P Ferreira; Michael K Pangburn; Gary S Gilkeson; Joshua M Thurman; Stephen Tomlinson; V Michael Holers
A targeted inhibitor of the complement alternative pathway reduces RPE injury and angiogenesis in models of age-related macular degeneration.
Advances in experimental medicine and biology 2010;703():137-49.
2009: Robert Campbell; Glinda S Cooper; Gary S Gilkeson
The impact of systemic lupus erythematosus on employment.
The Journal of rheumatology 2009;36(11):2470-5.
2009: Ryan Webb; Joan T Merrill; Jennifer A Kelly; Andrea Sestak; Kenneth M Kaufman; Carl D Langefeld; Julie Ziegler; Robert P Kimberly; Jeffrey C Edberg; Rosalind Ramsey-Goldman; Michelle Petri; John D Reveille; Graciela S Alarcón; Luis M Vilá; Marta E Alarcón-Riquelme; Judith A James; Gary S Gilkeson; Chaim O Jacob; Kathy L Moser; Patrick M Gaffney; Timothy J Vyse; Swapan K Nath; Peter Lipsky; John B Harley; Amr H Sawalha
A polymorphism within IL21R confers risk for systemic lupus erythematosus.
Arthritis and rheumatism 2009;60(8):2402-7.
2009: Bahram Namjou; Courtney Gray-McGuire; Andrea L Sestak; Gary S Gilkeson; Chaim O Jacob; J T Merrill; Judith A James; Edward K Wakeland; Quan-Zhen Li; Carl D Langefeld; J Divers; J Ziegler; Kathy L Moser; Jennifer A Kelly; Kenneth M Kaufman; John B Harley
Evaluation of C1q genomic region in minority racial groups of lupus.
Genes and immunity 2009;10(5):517-24.
2009: Don L Armstrong; Andreas Reiff; Barry L Myones; F P Quismorio; Marisa Klein-Gitelman; D McCurdy; Linda Wagner-Weiner; E Silverman; J O Ojwang; K M Kaufman; J A Kelly; J T Merrill; J B Harley; S-C Bae; Timothy J Vyse; Gary S Gilkeson; P M Gaffney; K L Moser; Chaim Putterman; J C Edberg; Elizabeth E Brown; J Ziegler; Carl D Langefeld; Raphael Zidovetzki; Chaim O Jacob
Identification of new SLE-associated genes with a two-step Bayesian study design.
Genes and immunity 2009;10(5):446-56.
2009: K B Douglas; D C Windels; J Zhao; A V Gadeliya; Hui Wu; K M Kaufman; J B Harley; J Merrill; R P Kimberly; G S Alarcón; Elizabeth E Brown; J C Edberg; R Ramsey-Goldman; Michelle Petri; J D Reveille; L M Vilá; P M Gaffney; Judith A James; K L Moser; M E Alarcón-Riquelme; Timothy J Vyse; Gary S Gilkeson; C O Jacob; J T Ziegler; Carl D Langefeld; Daniela Ulgiati; Betty P Tsao; Susan A Boackle
Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing.
Genes and immunity 2009;10(5):457-69.
2009: J S Bates; C J Lessard; J M Leon; T Nguyen; L J Battiest; J Rodgers; Kenneth M Kaufman; Judith A James; Gary S Gilkeson; Jennifer A Kelly; M B Humphrey; John B Harley; Courtney Gray-McGuire; Kathy L Moser; Patrick M Gaffney
Meta-analysis and imputation identifies a 109 kb risk haplotype spanning TNFAIP3 associated with lupus nephritis and hematologic manifestations.
Genes and immunity 2009;10(5):470-7.
2009: R Lu; G S Vidal; J A Kelly; Angelica Maria Delgado-Vega; X K Howard; S R Macwana; N Dominguez; W Klein; C Burrell; I T Harley; K M Kaufman; G R Bruner; K L Moser; P M Gaffney; Gary S Gilkeson; E K Wakeland; Q-Z Li; C D Langefeld; M C Marion; J Divers; G S Alarcón; Elizabeth E Brown; R P Kimberly; J C Edberg; R Ramsey-Goldman; J D Reveille; Gerald McGwin; L M Vilá; Michelle Petri; S-C Bae; S-K Cho; S-Y Bang; I Kim; Chan-Bum Choi; J Martin; T J Vyse; J T Merrill; J B Harley; M E Alarcón-Riquelme; S K Nath; J A James; J M Guthridge
Genetic associations of LYN with systemic lupus erythematosus.
Genes and immunity 2009;10(5):397-403.
2009: L Guo; H Deshmukh; R Lu; G S Vidal; J A Kelly; K M Kaufman; N Dominguez; W Klein; X Kim-Howard; G R Bruner; R Hal Scofield; K L Moser; P M Gaffney; I M Dozmorov; Gary S Gilkeson; E K Wakeland; Q-Z Li; C D Langefeld; M C Marion; A H Williams; J Divers; G S Alarcón; Elizabeth E Brown; R P Kimberly; J C Edberg; R Ramsey-Goldman; J D Reveille; Gerald McGwin; L M Vilá; Michelle Petri; T J Vyse; J T Merrill; J A James; S K Nath; J B Harley; J M Guthridge
Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population.
Genes and immunity 2009;10(5):531-8.
2009: Baerbel Rohrer; Qin Long; Beth Coughlin; R Brooks Wilson; Yuxiang Huang; Fei Qiao; Peter H Tang; Kannan Kunchithapautham; Gary S Gilkeson; Stephen Tomlinson
A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.
Investigative ophthalmology & visual science 2009;50(7):3056-64.
2009: Hideharu Sekine; Ricardo C Ferreira; Qiang Pan-Hammarstrom; Lennart Hammarström; Gary S Gilkeson; timothy wayne behrens
Comment on "Reassessment of the role of mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching".
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):4495-6; author reply 496-7.
2009: Chaim O Jacob; Jiankun Zhu; Don L Armstrong; Mei Yan; Jie Han; Xin J Zhou; James A Thomas; Andreas Reiff; Barry L Myones; Joshua O Ojwang; Kenneth M Kaufman; Marisa Klein-Gitelman; Deborah McCurdy; Linda Wagner-Weiner; Earl Silverman; Julie Ziegler; Jennifer A Kelly; Joan T Merrill; John B Harley; Rosalind Ramsey-Goldman; Luis M Vila; Sang-Cheol Bae; Timothy J Vyse; Gary S Gilkeson; Patrick M Gaffney; Kathy L Moser; Carl D Langefeld; Raphael Zidovetzki; Chandra Mohan
Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(15):6256-61.
2009: Bahram Namjou; Andrea L Sestak; Don L Armstrong; Raphael Zidovetzki; Jennifer A Kelly; Noam Jacob; Voicu Ciobanu; Kenneth M Kaufman; Joshua O Ojwang; Julie Ziegler; Francesco P Quismorio; Andreas Reiff; Barry L Myones; Guthridge Joel; Swapan K Nath; Gail R Bruner; Ruth Mehrian-Shai; Earl Silverman; Marisa Klein-Gitelman; Deborah McCurdy; Linda Wagner-Weiner; James J Nocton; Chaim Putterman; Sang-Cheol Bae; Yun Jung Kim; Michelle Petri; John D Reveille; Timothy J Vyse; Gary S Gilkeson; Diane L Kamen; Marta E Alarcón-Riquelme; Patrick M Gaffney; Kathy L Moser; Joan T Merrill; R Hal Scofield; Judith A James; Carl D Langefeld; John B Harley; Chaim O Jacob
High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.
Arthritis and rheumatism 2009;60(4):1085-95.
2009: Ryan Webb; Jonathan Wren; Matlock Jeffries; Jennifer A Kelly; Kenneth M Kaufman; Yuhong Tang; Mark Barton Frank; Joan Merrill; Robert P Kimberly; Jeffrey C Edberg; Rosalind Ramsey-Goldman; Michelle Petri; John D Reveille; Graciela S Alarcón; Luis M Vilá; Marta E Alarcón-Riquelme; Judith A James; Timothy J Vyse; Kathy L Moser; Patrick M Gaffney; Gary S Gilkeson; John B Harley; Amr H Sawalha
Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus.
Arthritis and rheumatism 2009;60(4):1076-84.
2009: Kui Liu; Quan-Zhen Li; Angelica Maria Delgado-Vega; Anna-Karin Abelson; Elena Sánchez; Jennifer A Kelly; Li Li; Yang Liu; Jinchun Zhou; Mei Yan; Qiu Ye; Shenxi Liu; Chun Xie; Xin J Zhou; Sharon A Chung; Bernardo Pons-Estel; Torsten Witte; Enrique de Ramón; Sang-Cheol Bae; Nadia Barizzone; Gian Domenico Sebastiani; Joan T Merrill; Peter K Gregersen; Gary S Gilkeson; Robert P Kimberly; Timothy J Vyse; Il Kim; Sandra D'Alfonso; Javier Martin; John B Harley; Lindsey A Criswell; Edward K Wakeland; Marta E Alarcón-Riquelme; Chandra Mohan
Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans.
The Journal of clinical investigation 2009;119(4):911-23.
2009: Deborah E Keil; Margie M Peden-Adams; Stacy Wallace; Phillip Ruiz; Gary S Gilkeson
Assessment of trichloroethylene (TCE) exposure in murine strains genetically-prone and non-prone to develop autoimmune disease.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 2009;44(5):443-53.
2009: Deborah E Keil; W David McGuinn; Andrew Dudley; Jackie G EuDaly; Gary S Gilkeson; Margie M Peden-Adams
N,N,-diethyl-m-toluamide (DEET) suppresses humoral immunological function in B6C3F1 mice.
Toxicological sciences : an official journal of the Society of Toxicology 2009;108(1):110-23.
2009: Ashley J Snider; Toshihiko Kawamori; Sarah G Bradshaw; K Alexa Orr; Gary S Gilkeson; Yusuf A Hannun; Lina M Obeid
A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(1):143-52.
2008: Ted R Mikuls; L B Hughes; Andrew Westfall; V Michael Holers; Lezlie A Parrish; D van der Heijde; M van Everdingen; Graciela S Alarcón; Doyt L Conn; Beth L Jonas; Leigh F Callahan; Edwin A Smith; Gary S Gilkeson; George Howard; Larry W Moreland; S Louis Bridges
Cigarette smoking, disease severity and autoantibody expression in African Americans with recent-onset rheumatoid arthritis.
Annals of the rheumatic diseases 2008;67(11):1529-34.
2008: Chinedu J Njoku; Sally Self; Phillip Ruiz; Ann F Hofbauer; Gary S Gilkeson; Jim Oates
Inducible nitric oxide synthase inhibitor SD-3651 reduces proteinuria in MRL/lpr mice deficient in the NOS2 gene.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2008;56(7):911-9.
2008: Margie M Peden-Adams; Jackie G EuDaly; A Michelle Lee; Julie Miller; Deborah E Keil; Gary S Gilkeson
Lifetime exposure to trichloroethylene (TCE) does not accelerate autoimmune disease in MRL +/+ mice.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 2008;43(12):1402-9.
2008: Sarah Bradshaw; W Jim Zheng; Lam C Tsoi; Gary S Gilkeson; Xian-Kui John Zhang
A role for Fli-1 in B cell proliferation: implications for SLE pathogenesis.
Clinical immunology (Orlando, Fla.) 2008;129(1):19-30.
2008: Christopher M Reilly; Megan Thomas; Robert M Gogal; Selen Olgun; Arben Santo; Renna Sodhi; Eileen T Samy; Stanford L Peng; Gary S Gilkeson; Nilamadhab Mishra
The histone deacetylase inhibitor trichostatin A upregulates regulatory T cells and modulates autoimmunity in NZB/W F1 mice.
Journal of autoimmunity 2008;31(2):123-30.
2008: Xian-Kui John Zhang; Omar Moussa; Amanda C Larue; Sarah Bradshaw; Ivan D Molano; Demetri D Spyropoulos; Gary S Gilkeson; Dennis Watson
The transcription factor Fli-1 modulates marginal zone and follicular B cell development in mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(3):1644-54.
2008: C G Parks; Glinda S Cooper; Mary Anne Dooley; M M Park; E L Treadwell; Gary S Gilkeson
Childhood agricultural and adult occupational exposures to organic dusts in a population-based case-control study of systemic lupus erythematosus.
Lupus 2008;17(8):711-9.
2008: John L Svenson; Jackie G EuDaly; Phillip Ruiz; Kenneth S Korach; Gary S Gilkeson
Impact of estrogen receptor deficiency on disease expression in the NZM2410 lupus prone mouse.
Clinical immunology (Orlando, Fla.) 2008;128(2):259-68.
2008: Margie M Peden-Adams; Jennifer M Keller; Jackie G EuDaly; Jennifer Berger; Gary S Gilkeson; Deborah E Keil
Suppression of humoral immunity in mice following exposure to perfluorooctane sulfonate.
Toxicological sciences : an official journal of the Society of Toxicology 2008;104(1):144-54.
2008: Diane L Kamen; Mia Barron; Tia M Parker; Stephanie R Shaftman; Gail R Bruner; Teresa Aberle; Judith A James; R Hal Scofield; John B Harley; Gary S Gilkeson
Autoantibody prevalence and lupus characteristics in a unique African American population.
Arthritis and rheumatism 2008;58(5):1237-47.
2008: Erica Anderson; Paul Nietert; Diane L Kamen; Gary S Gilkeson
Ethnic disparities among patients with systemic lupus erythematosus in South Carolina.
The Journal of rheumatology 2008;35(5):819-25.
2008: Robert Campbell; Glinda S Cooper; Gary S Gilkeson
Two aspects of the clinical and humanistic burden of systemic lupus erythematosus: mortality risk and quality of life early in the course of disease.
Arthritis and rheumatism 2008;59(4):458-64.
2008: Laura B Hughes; Dahliann Morrison; James M Kelley; Miguel A Padilla; Laura Kelly Vaughan; Andrew Westfall; Harshit Dwivedi; Ted R Mikuls; V Michael Holers; Lezlie A Parrish; Graciela S Alarcón; Doyt L Conn; Beth L Jonas; Leigh F Callahan; Edwin A Smith; Gary S Gilkeson; George Howard; Larry W Moreland; Nick Patterson; David Reich; S Louis Bridges
The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture.
Arthritis and rheumatism 2008;58(2):349-58.
2008: Swapan K Nath; Shizhong Han; Xana R Kim-Howard; Jennifer A Kelly; Parvathi Viswanathan; Gary S Gilkeson; Wei Chen; Cheng Zhu; Rodger P McEver; Robert P Kimberly; Marta E Alarcón-Riquelme; Timothy J Vyse; Quan-Zhen Li; Edward K Wakeland; Joan T Merrill; Judith A James; Kenneth M Kaufman; Guthridge Joel; John B Harley
A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.
Nature genetics 2008;40(2):152-4.
2008: John B Harley; Marta E Alarcón-Riquelme; Lindsey A Criswell; Chaim O Jacob; Robert P Kimberly; Kathy L Moser; Betty P Tsao; Timothy J Vyse; Carl D Langefeld; Swapan K Nath; Guthridge Joel; Beth L Cobb; Daniel B Mirel; Miranda C Marion; Adrienne H Williams; Jasmin Divers; Wei Wang; Summer G Frank; Bahram Namjou; Stacey B Gabriel; Annette T Lee; Peter K Gregersen; timothy wayne behrens; Kimberly E Taylor; Michelle Fernando; Raphael Zidovetzki; Patrick M Gaffney; Jeffrey C Edberg; John D Rioux; Joshua O Ojwang; Judith A James; Joan T Merrill; Gary S Gilkeson; Michael F Seldin; Hong Yin; Emily C Baechler; Quan-Zhen Li; Edward K Wakeland; Gail R Bruner; Kenneth M Kaufman; Jennifer A Kelly
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
Nature genetics 2008;40(2):204-10.
2008: Carl Atkinson; Fei Qiao; Hongbin Song; Gary S Gilkeson; Stephen Tomlinson
Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(2):1231-8.
2008: Shizhong Han; Guthridge Joel; Isaac T W Harley; Andrea L Sestak; Xana Kim-Howard; Kenneth M Kaufman; Bahram Namjou; Harshal Deshmukh; Gail R Bruner; Luis R Espinoza; Gary S Gilkeson; John B Harley; Judith A James; Swapan K Nath
Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction.
PloS one 2008;3(3):e0001757.
2008: Amr H Sawalha; Ryan Webb; Shizhong Han; Jennifer A Kelly; Kenneth M Kaufman; Robert P Kimberly; Marta E Alarcón-Riquelme; Judith A James; Timothy J Vyse; Gary S Gilkeson; Chan-Bum Choi; R Hal Scofield; Sang-Cheol Bae; Swapan K Nath; John B Harley
Common variants within MECP2 confer risk of systemic lupus erythematosus.
PloS one 2008;3(3):e1727.
2008: Jim Oates; Stephanie R Shaftman; Sally Self; Gary S Gilkeson
Association of serum nitrate and nitrite levels with longitudinal assessments of disease activity and damage in systemic lupus erythematosus and lupus nephritis.
Arthritis and rheumatism 2008;58(1):263-72.
2008: Tamara Nowling; Jennifer Dziadyk Fulton; Katherine Chike-Harris; Gary S Gilkeson
Ets factors and a newly identified polymorphism regulate Fli1 promoter activity in lymphocytes.
Molecular immunology 2008;45(1):1-12.
2007: Jim Oates; Libby W Farrelly; Ann F Hofbauer; Wei Wang; Gary S Gilkeson
Association of reactive oxygen and nitrogen intermediate and complement levels with apoptosis of peripheral blood mononuclear cells in lupus patients.
Arthritis and rheumatism 2007;56(11):3738-47.
2007: Baerbel Rohrer; Yao Guo; Kannan Kunchithapautham; Gary S Gilkeson
Eliminating complement factor D reduces photoreceptor susceptibility to light-induced damage.
Investigative ophthalmology & visual science 2007;48(11):5282-9.
2007: Henda Bouali; Paul Nietert; Tamara Nowling; Janardan P Pandey; Mary Anne Dooley; Glinda Cooper; John Harley; Diane L Kamen; Jim Oates; Gary S Gilkeson
Association of the G-463A myeloperoxidase gene polymorphism with renal disease in African Americans with systemic lupus erythematosus.
The Journal of rheumatology 2007;34(10):2028-34.
2007: Glinda S Cooper; Edward L Treadwell; E William St Clair; Gary S Gilkeson; Mary Anne Dooley
Sociodemographic associations with early disease damage in patients with systemic lupus erythematosus.
Arthritis and rheumatism 2007;57(6):993-9.
2007: Amanda M Lenderink; Katharine Liegel; Danica Ljubanović; Kathrin E Coleman; Gary S Gilkeson; V Michael Holers; Joshua M Thurman
The alternative pathway of complement is activated in the glomeruli and tubulointerstitium of mice with adriamycin nephropathy.
American journal of physiology. Renal physiology 2007;293(2):F555-64.
2007: Jessy J Alexander; Alexander Jacob; Paul Vezina; Hideharu Sekine; Gary S Gilkeson; Richard J Quigg
Absence of functional alternative complement pathway alleviates lupus cerebritis.
European journal of immunology 2007;37(6):1691-701.
2007: Hideharu Sekine; Ricardo C Ferreira; Qiang Pan-Hammarstrom; Robert R Graham; Beth Ziemba; Sandra S de Vries; Jiabin Liu; Keli L Hippen; Thearith Koeuth; Ward A Ortmann; Akiko Iwahori; Margaret K Elliott; Steven Offer; Cara Skon; Likun Du; Jill Novitzke; Annette T Lee; Nianxi Zhao; Joshua D Tompkins; David Altshuler; Peter K Gregersen; Charlotte Cunningham-Rundles; Reuben S Harris; Chengtao Her; David L Nelson; Lennart Hammarström; Gary S Gilkeson; timothy wayne behrens
Role for Msh5 in the regulation of Ig class switch recombination.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(17):7193-8.
2007: Takashi Miwa; Michael A Maldonado; Lin Zhou; Koei Yamada; Gary S Gilkeson; Robert A Eisenberg; Wen-Chao Song
Decay-accelerating factor ameliorates systemic autoimmune disease in MRL/lpr mice via both complement-dependent and -independent mechanisms.
The American journal of pathology 2007;170(4):1258-66.
2006: Jim Oates; Gary S Gilkeson
The biology of nitric oxide and other reactive intermediates in systemic lupus erythematosus.
Clinical immunology (Orlando, Fla.) 2006;121(3):243-50.
2006: Hideharu Sekine; Kareem L Graham; Shenru Zhao; Margaret K Elliott; Phillip Ruiz; Paul J Utz; Gary S Gilkeson
Role of MHC-linked genes in autoantigen selection and renal disease in a murine model of systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):7423-34.
2006: Ted R Mikuls; V Michael Holers; Lezlie A Parrish; Kristine A Kuhn; Doyt L Conn; Gary S Gilkeson; Edwin A Smith; Diane L Kamen; Beth L Jonas; Leigh F Callahan; Graciela S Alarcón; George Howard; Larry W Moreland; S Louis Bridges
Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in African Americans with early rheumatoid arthritis.
Arthritis and rheumatism 2006;54(9):3057-9.
2006: Tamara Nowling; Gary S Gilkeson
Regulation of Fli1 gene expression and lupus.
Autoimmunity reviews 2006;5(6):377-82.
2006: Xiaoping Qing; Jiri Zavadil; Michelle B Crosby; Mark P Hogarth; Bevra H Hahn; Chandra Mohan; Gary S Gilkeson; Erwin P Bottinger; Chaim Putterman
Nephritogenic anti-DNA antibodies regulate gene expression in MRL/lpr mouse glomerular mesangial cells.
Arthritis and rheumatism 2006;54(7):2198-210.
2006: Sarah Gallant; Gary S Gilkeson
ETS transcription factors and regulation of immunity.
Archivum immunologiae et therapiae experimentalis 2006;54(3):149-63.
2006: Christopher M Reilly; Selen Olgun; David Goodwin; Robert M Gogal; Arben Santo; Jason W Romesburg; S Ansar Ahmed; Gary S Gilkeson
Interferon regulatory factor-1 gene deletion decreases glomerulonephritis in MRL/lpr mice.
European journal of immunology 2006;36(5):1296-308.
2006: Jiabin Liu; George Karypis; Keli L Hippen; A L Vegoe; Phillip Ruiz; Gary S Gilkeson; timothy wayne behrens
Genomic view of systemic autoimmunity in MRLlpr mice.
Genes and immunity 2006;7(2):156-68.
2006: Diane L Kamen; Glinda S Cooper; Henda Bouali; Stephanie R Shaftman; Bruce W Hollis; Gary S Gilkeson
Vitamin D deficiency in systemic lupus erythematosus.
Autoimmunity reviews 2006;5(2):114-7.
2006: Michelle B Crosby; Xian-Kui John Zhang; Tamara Nowling; John L Svenson; Christopher J Nicol; Frank J Gonzalez; Gary S Gilkeson
Inflammatory modulation of PPAR gamma expression and activity.
Clinical immunology (Orlando, Fla.) 2006;118(2-3):276-83.
2006: Margie M Peden-Adams; Jackie G EuDaly; Lauren M Heesemann; Joshua Smythe; Julie Miller; Gary S Gilkeson; Deborah E Keil
Developmental immunotoxicity of trichloroethylene (TCE): studies in B6C3F1 mice.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 2006;41(3):249-71.
2005: Henda Bouali; Gary S Gilkeson
New therapies and preventive strategies to treat and minimize damage in lupus.
Current rheumatology reports 2005;7(6):457-62.
2005: Ellen M Ginzler; Mary Anne Dooley; Cynthia Aranow; Mimi Y Kim; Jill P Buyon; Joan T Merrill; Michelle Petri; Gary S Gilkeson; Daniel J Wallace; Michael H Weisman; Gerald B Appel
Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis.
The New England journal of medicine 2005;353(21):2219-28.
2005: Michelle B Crosby; John L Svenson; Gary S Gilkeson; Tamara Nowling
A novel PPAR response element in the murine iNOS promoter.
Molecular immunology 2005;42(11):1303-10.
2005: Maria K Haraldsson; Nathanial G dela Paz; Jason G Kuan; Gary S Gilkeson; Argyrios N Theofilopoulos; Dwight H Kono
Autoimmune alterations induced by the New Zealand Black Lbw2 locus in BWF1 mice.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):5065-73.
2005: Christine G Parks; Glinda S Cooper; Lori L Hudson; Mary Anne Dooley; Edward L Treadwell; E William St Clair; Gary S Gilkeson; Janardan P Pandey
Association of Epstein-Barr virus with systemic lupus erythematosus: effect modification by race, age, and cytotoxic T lymphocyte-associated antigen 4 genotype.
Arthritis and rheumatism 2005;52(4):1148-59.
2005: Joshua M Thurman; Damian M Kraus; Guillermina Girardi; Dennis E Hourcade; Hee J Kang; patricia royer; Lynne M Mitchell; Patricia C Giclas; Jane Salmon; Gary S Gilkeson; V Michael Holers
A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice.
Molecular immunology 2005;42(1):87-97.
2005: Michelle B Crosby; John L Svenson; Xian-Kui John Zhang; Christopher J Nicol; Frank J Gonzalez; Gary S Gilkeson
Peroxisome proliferation-activated receptor (PPAR)gamma is not necessary for synthetic PPARgamma agonist inhibition of inducible nitric-oxide synthase and nitric oxide.
The Journal of pharmacology and experimental therapeutics 2005;312(1):69-76.
2004: Xian-Kui John Zhang; Sarah Gallant; Ivan D Molano; Omar Moussa; Phillip Ruiz; Demetri D Spyropoulos; Dennis Watson; Gary S Gilkeson
Decreased expression of the Ets family transcription factor Fli-1 markedly prolongs survival and significantly reduces renal disease in MRL/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(10):6481-9.
2004: Glinda S Cooper; Christine G Parks; Edward L Treadwell; E William St Clair; Gary S Gilkeson; Mary Anne Dooley
Occupational risk factors for the development of systemic lupus erythematosus.
The Journal of rheumatology 2004;31(10):1928-33.
2004: Christopher M Reilly; Nilamadhab Mishra; Julie M Miller; Dimple Joshi; Phillip Ruiz; Victoria M Richon; Paul A Marks; Gary S Gilkeson
Modulation of renal disease in MRL/lpr mice by suberoylanilide hydroxamic acid.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):4171-8.
2004: Glenn Douglas; Chris Reilly; Mary Anne Dooley; Grier Page; Glinda Cooper; Gary S Gilkeson
Angiotensin-converting enzyme (insertion/deletion) and endothelial nitric oxide synthase polymorphisms in patients with systemic lupus erythematosus.
The Journal of rheumatology 2004;31(9):1756-62.
2004: Deborah E Keil; Andrew Dudley; Jackie G EuDaly; J Dempsey; Leon F Butterworth; Gary S Gilkeson; Margie M Peden-Adams
Immunological and hematological effects observed in B6C3F1 mice exposed to JP-8 jet fuel for 14 days.
Journal of toxicology and environmental health. Part A 2004;67(14):1109-29.
2004: Christine G Parks; Janardan P Pandey; Mary Anne Dooley; Edward L Treadwell; E William St Clair; Gary S Gilkeson; Carol A Feghali-Bostwick; Carol L Feghali-Botswick; Glinda S Cooper
Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism.
Human immunology 2004;65(6):622-31.
2004: Hideharu Sekine; Hiroshi Watanabe; Gary S Gilkeson
Enrichment of anti-glomerular antigen antibody-producing cells in the kidneys of MRL/MpJ-Fas(lpr) mice.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(6):3913-21.
2004: Margie M Peden-Adams; Andrew Dudley; Jackie G EuDaly; C T Allen; Gary S Gilkeson; Deborah E Keil
Pyridostigmine bromide (PYR) alters immune function in B6C3F1 mice.
Immunopharmacology and immunotoxicology 2004;26(1):1-15.
2004: Christine G Parks; Lori L Hudson; Glinda S Cooper; Mary Anne Dooley; Edward L Treadwell; E William St Clair; Gary S Gilkeson; Janardan P Pandey
CTLA-4 gene polymorphisms and systemic lupus erythematosus in a population-based study of whites and African-Americans in the southeastern United States.
Lupus 2004;13(10):784-91.
2004: Jim Oates; Gary S Gilkeson
Nitric oxide induces apoptosis in spleen lymphocytes from MRL/lpr mice.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2004;52(1):62-71.
2004: Glinda S Cooper; Edward L Treadwell; Mary Anne Dooley; E William St Clair; Gary S Gilkeson; Jack A Taylor
N-acetyl transferase genotypes in relation to risk of developing systemic lupus erythematosus.
The Journal of rheumatology 2004;31(1):76-80.
2004: Margaret K Elliott; Tambi Jarmi; Phillip Ruiz; Yuanyuan Xu; V Michael Holers; Gary S Gilkeson
Effects of complement factor D deficiency on the renal disease of MRL/lpr mice.
Kidney international 2004;65(1):129-38.
2004: Christine G Parks; Glinda S Cooper; Mary Anne Dooley; Edward L Treadwell; E William St Clair; Gary S Gilkeson; Janardan P Pandey
Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States.
Annals of the rheumatic diseases 2004;63(1):91-4.
2003: Byron P Croker; Gary S Gilkeson; Laurence Morel
Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus.
Genes and immunity 2003;4(8):575-85.
2003: Kelly Guyton; Basilia Zingarelli; Sarah Ashton; Giuseppe Teti; George E Tempel; Chris Reilly; Gary S Gilkeson; Perry V Halushka; James A Cook
Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli.
Shock (Augusta, Ga.) 2003;20(1):56-62.
2003: Ivan D Molano; Shakisha Redmond; Hideharu Sekine; Xian-Kui John Zhang; Chris Reilly; Florence Hutchison; Phillip Ruiz; Gary S Gilkeson
Effect of genetic deficiency of terminal deoxynucleotidyl transferase on autoantibody production and renal disease in MRL/lpr mice.
Clinical immunology (Orlando, Fla.) 2003;107(3):186-97.
2003: Nilamadhab Mishra; Christopher M Reilly; Doris R Brown; Phillip Ruiz; Gary S Gilkeson
Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse.
The Journal of clinical investigation 2003;111(4):539-52.
2003: Patricia A Fraser; Wei-Zi Ding; Mehrdad Mohseni; Edward L Treadwell; Mary Anne Dooley; E William St Clair; Gary S Gilkeson; Glinda S Cooper
Glutathione S-transferase M null homozygosity and risk of systemic lupus erythematosus associated with sun exposure: a possible gene-environment interaction for autoimmunity.
The Journal of rheumatology 2003;30(2):276-82.
2003: Joshua M Thurman; Danica Ljubanovic; Charles L Edelstein; Gary S Gilkeson; V Michael Holers
Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(3):1517-23.
2003: Jim Oates; Marc C Levesque; Maurine R Hobbs; Erica Grace Smith; Ivan D Molano; Grier P Page; Bruce S Hill; J Brice Weinberg; Glinda S Cooper; Gary S Gilkeson
Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in african-americans.
The Journal of rheumatology 2003;30(1):60-7.
2002: Glinda S Cooper; Mary Anne Dooley; Edward L Treadwell; E William St Clair; Gary S Gilkeson
Risk factors for development of systemic lupus erythematosus: allergies, infections, and family history.
Journal of clinical epidemiology 2002;55(10):982-9.
2002: Jim Oates; Gary S Gilkeson
Mediators of injury in lupus nephritis.
Current opinion in rheumatology 2002;14(5):498-503.
2002: Christine G Parks; Glinda S Cooper; Leena A Nylander-French; Wayne T Sanderson; John M Dement; Philip L Cohen; Mary Anne Dooley; Edward L Treadwell; E William St Clair; Gary S Gilkeson; Jane Hoppin; David A Savitz
Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States.
Arthritis and rheumatism 2002;46(7):1840-50.
2002: Glinda S Cooper; Mary Anne Dooley; Edward L Treadwell; E William St Clair; Gary S Gilkeson
Hormonal and reproductive risk factors for development of systemic lupus erythematosus: results of a population-based, case-control study.
Arthritis and rheumatism 2002;46(7):1830-9.
2002: Jim Oates; Christopher M Reilly; Michelle B Crosby; Gary S Gilkeson
Peroxisome proliferator-activated receptor gamma agonists: potential use for treating chronic inflammatory diseases.
Arthritis and rheumatism 2002;46(3):598-605.
2002: Christopher M Reilly; Libby W Farrelly; Dana Viti; Shakisha T Redmond; Florence Hutchison; Phillip Ruiz; Pam Manning; Jane Connor; Gary S Gilkeson
Modulation of renal disease in MRL/lpr mice by pharmacologic inhibition of inducible nitric oxide synthase.
Kidney international 2002;61(3):839-46.
2002: Glinda S Cooper; Christine G Parks; Edward L Treadwell; E William St Clair; Gary S Gilkeson; Philip L Cohen; Robert A S Roubey; Mary Anne Dooley
Differences by race, sex and age in the clinical and immunologic features of recently diagnosed systemic lupus erythematosus patients in the southeastern United States.
Lupus 2002;11(3):161-7.
2002: Christopher M Reilly; Gary S Gilkeson
Use of genetic knockouts to modulate disease expression in a murine model of lupus, MRL/lpr mice.
Immunologic research 2002;25(2):143-53.
2001: Glinda S Cooper; Mary Anne Dooley; Edward L Treadwell; E William St Clair; Gary S Gilkeson
Smoking and use of hair treatments in relation to risk of developing systemic lupus erythematosus.
The Journal of rheumatology 2001;28(12):2653-6.
2001: Margie M Peden-Adams; Jackie G EuDaly; E Eudaly; Andrew Dudley; J Zeigler; A Lee; J Robbs; Gary S Gilkeson; Deborah E Keil
Evaluation of immunotoxicity induced by single or concurrent exposure to N,N-diethyl-m-toluamide (DEET), pyridostigmine bromide (PYR), and JP-8 jet fuel.
Toxicology and industrial health 2001;17(5-10):192-209.
2001: Hideharu Sekine; Christopher M Reilly; Ivan D Molano; Gérard Garnier; Antonella Circolo; Phillip Ruiz; V Michael Holers; S A Boackle; Gary S Gilkeson
Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6444-51.
2001: Anastasios V Korompilias; Gary S Gilkeson; Anthony V Seaber; James R Urbaniak
Hemorrhage and thrombus formation in early experimental osteonecrosis.
Clinical orthopaedics and related research 2001;(386):11-8.
2001: Kelly Guyton; R Bond; Chris Reilly; Gary S Gilkeson; Perry V Halushka; James A Cook
Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
Journal of leukocyte biology 2001;69(4):631-8.
2001: Christopher M Reilly; Jim Oates; J Sudian; Michelle B Crosby; Perry V Halushka; Gary S Gilkeson
Prostaglandin J(2) inhibition of mesangial cell iNOS expression.
Clinical immunology (Orlando, Fla.) 2001;98(3):337-45.
2001: Janardan P Pandey; Glinda S Cooper; Edward L Treadwell; Gary S Gilkeson; E William St Clair; Mary Anne Dooley
Immunoglobulin GM and KM allotypes in systemic lupus erythematosus.
Experimental and clinical immunogenetics 2001;18(3):117-22.
2000: T Keng; Chris Privalle; Gary S Gilkeson; J B Weinberg
Peroxynitrite formation and decreased catalase activity in autoimmune MRL-lpr/lpr mice.
Molecular medicine (Cambridge, Mass.) 2000;6(9):779-92.
2000: Laurence Morel; Byron P Croker; Kim R M Blenman; Chandra Mohan; G Huang; Gary S Gilkeson; Edward K Wakeland
Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6670-5.
2000: Christopher M Reilly; Jim Oates; James A Cook; J D Morrow; Perry V Halushka; Gary S Gilkeson
Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1498-504.
2000: Hiroshi Watanabe; Gérard Garnier; Antonella Circolo; Rick A Wetsel; Phillip Ruiz; V Michael Holers; S A Boackle; HR Colten; Gary S Gilkeson
Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):786-94.
2000: Ivan D Molano; MK Wloch; A A Alexander; Hiroshi Watanabe; Gary S Gilkeson
Effect of a genetic deficiency of terminal deoxynucleotidyl transferase on autoantibody production by C57BL6 Fas(lpr) mice.
Clinical immunology (Orlando, Fla.) 2000;94(1):24-32.
1999: Jim Oates; E F Christensen; Christopher M Reilly; Sally Self; Gary S Gilkeson
Prospective measure of serum 3-nitrotyrosine levels in systemic lupus erythematosus: correlation with disease activity.
Proceedings of the Association of American Physicians 1999;111(6):611-21.
1999: Chandra Mohan; Laurence Morel; P Yang; H Watanabe; Byron P Croker; Gary S Gilkeson; Edward K Wakeland
Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies.
The Journal of clinical investigation 1999;103(12):1685-95.
1999: Gary S Gilkeson; C Cannon; Jim Oates; Chris Reilly; D Goldman; Michelle Petri
Correlation of serum measures of nitric oxide production with lupus disease activity.
The Journal of rheumatology 1999;26(2):318-24.
1998: Gary S Gilkeson; J Conover; M Halpern; David S Pisetsky; A Feagin; D M Klinman
Effects of bacterial DNA on cytokine production by (NZB/NZW)F1 mice.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):3890-5.
1998: Glinda S Cooper; Mary Anne Dooley; Edward L Treadwell; E William St Clair; Christine G Parks; Gary S Gilkeson
Hormonal, environmental, and infectious risk factors for developing systemic lupus erythematosus.
Arthritis and rheumatism 1998;41(10):1714-24.
1998: Hiroshi Watanabe; D Sherris; Gary S Gilkeson
Soluble CD16 in the treatment of murine lupus nephritis.
Clinical immunology and immunopathology 1998;88(1):91-5.
1998: J B Weinberg; Gary S Gilkeson; R P Mason; W Chamulitrat
Nitrosylation of blood hemoglobin and renal nonheme proteins in autoimmune MRL-lpr/lpr mice.
Free radical biology & medicine 1998;24(1):191-6.
1997: MK Wloch; Stephen H Clarke; Gary S Gilkeson
Influence of VH CDR3 arginine and light chain pairing on DNA reactivity of a bacterial DNA-induced anti-DNA antibody from a BALB/c mouse.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):6083-90.
1997: Anastasios V Korompilias; Gary S Gilkeson; Thomas L Ortel; Anthony V Seaber; James R Urbaniak
Anticardiolipin antibodies and osteonecrosis of the femoral head.
Clinical orthopaedics and related research 1997;(345):174-80.
1997: Ester Carballo; Gary S Gilkeson; Perry Blackshear
Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction.
The Journal of clinical investigation 1997;100(5):986-95.
1997: Gary S Gilkeson; J S Mudgett; Michael F Seldin; Phillip Ruiz; A A Alexander; Mary A Misukonis; David S Pisetsky; J Brice Weinberg
Clinical and serologic manifestations of autoimmune disease in MRL-lpr/lpr mice lacking nitric oxide synthase type 2.
The Journal of experimental medicine 1997;186(3):365-73.
1997: MK Wloch; A L Alexander; Anne M Pippen; David S Pisetsky; Gary S Gilkeson
Molecular properties of anti-DNA induced in preautoimmune NZB/W mice by immunization with bacterial DNA.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(9):4500-6.
1997: Jim Oates; Phillip Ruiz; A Alexander; Anne M Pippen; Gary S Gilkeson
Effect of late modulation of nitric oxide production on murine lupus.
Clinical immunology and immunopathology 1997;83(1):86-92.
1997: D S Pisetsky; Gary S Gilkeson; E W St Clair
Systemic lupus erythematosus. Diagnosis and treatment.
The Medical clinics of North America 1997;81(1):113-28.
1996: E W St Clair; W E Wilkinson; T Lang; L Sanders; Mary A Misukonis; Gary S Gilkeson; David S Pisetsky; D I Granger; J Brice Weinberg
Increased expression of blood mononuclear cell nitric oxide synthase type 2 in rheumatoid arthritis patients.
The Journal of experimental medicine 1996;184(3):1173-8.
1996: M K Wloch; A L Alexander; Anne M Pippen; David S Pisetsky; Gary S Gilkeson
Differences in V kappa gene utilization and VH CDR3 sequence among anti-DNA from C3H-lpr mice and lupus mice with nephritis.
European journal of immunology 1996;26(9):2225-33.
1996: J B Lefkowith; R Di Valerio; J Norris; G D Glick; A L Alexander; L Jackson; Gary S Gilkeson
Murine glomerulotropic monoclonal antibodies are highly oligoclonal and exhibit distinctive molecular features.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(3):1297-305.
1996: J B Lefkowith; Gary S Gilkeson
Nephritogenic autoantibodies in lupus: current concepts and continuing controversies.
Arthritis and rheumatism 1996;39(6):894-903.
1996: G A Taylor; Ester Carballo; D M Lee; Wi S Lai; M J Thompson; Dhavalkumar D Patel; D I Schenkman; Gary S Gilkeson; H E Broxmeyer; B F Haynes; Perry Blackshear
A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency.
Immunity 1996;4(5):445-54.
1996: RP Polisson; Gary S Gilkeson; E H Pyun; D S Pisetsky; Edwin A Smith; Lee S Simon
A multicenter trial of recombinant human interferon gamma in patients with systemic sclerosis: effects on cutaneous fibrosis and interleukin 2 receptor levels.
The Journal of rheumatology 1996;23(4):654-8.
1996: Gary S Gilkeson; Phillip Ruiz; Anne M Pippen; A L Alexander; J B Lefkowith; David S Pisetsky
Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA.
The Journal of experimental medicine 1996;183(4):1389-97.
1996: Gary S Gilkeson; N B Allen
Retroperitoneal fibrosis. A true connective tissue disease.
Rheumatic diseases clinics of North America 1996;22(1):23-38.
1995: Gary S Gilkeson; K Bernstein; Anne M Pippen; Stephen H Clarke; T Marion; David S Pisetsky; Phillip Ruiz; J B Lefkowith
The influence of variable-region somatic mutations on the specificity and pathogenicity of murine monoclonal anti-DNA antibodies.
Clinical immunology and immunopathology 1995;76(1 Pt 1):59-67.
1995: Gary S Gilkeson; Anne M Pippen; David S Pisetsky
Induction of cross-reactive anti-dsDNA antibodies in preautoimmune NZB/NZW mice by immunization with bacterial DNA.
The Journal of clinical investigation 1995;95(3):1398-402.
1994: J Brice Weinberg; D L Granger; David S Pisetsky; Michael F Seldin; Mary A Misukonis; S N Mason; Anne M Pippen; Phillip Ruiz; E R Wood; Gary S Gilkeson
The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine.
The Journal of experimental medicine 1994;179(2):651-60.
1993: Gary S Gilkeson; Phillip Ruiz; D Howell; J B Lefkowith; David S Pisetsky
Induction of immune-mediated glomerulonephritis in normal mice immunized with bacterial DNA.
Clinical immunology and immunopathology 1993;68(3):283-92.
1993: Gary S Gilkeson; D D Bloom; David S Pisetsky; Stephen H Clarke
Molecular characterization of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. Differences from spontaneous anti-DNA in the content and location of VH CDR3 arginines.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(3):1353-64.
1993: S M Palmer; Gary S Gilkeson; D S Pisetsky
Effect of sex on the induction of anti-DNA antibodies in normal mice immunized with bacterial DNA.
Lupus 1993;2(4):251-5.
1993: J P Messina; Gary S Gilkeson; D S Pisetsky
The influence of DNA structure on the in vitro stimulation of murine lymphocytes by natural and synthetic polynucleotide antigens.
Cellular immunology 1993;147(1):148-57.
1993: K Bernstein; D Bolshoun; Gary S Gilkeson; T Munns; J B Lefkowith
Detection of glomerular-binding immune elements in murine lupus using a tissue-based ELISA.
Clinical and experimental immunology 1993;91(3):449-55.
1993: E H Pyun; David S Pisetsky; Gary S Gilkeson
The fine specificity of monoclonal anti-DNA antibodies induced in normal mice by immunization with bacterial DNA.
Journal of autoimmunity 1993;6(1):11-26.
1992: M L Watson; Jaya K Rao; Gary S Gilkeson; Phillip Ruiz; E M Eicher; David S Pisetsky; A Matsuzawa; J M Rochelle; Michael F Seldin
Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci.
The Journal of experimental medicine 1992;176(6):1645-56.
1992: Gary S Gilkeson; Robert F Spurney; Thomas M Coffman; Roger Kurlander; Phillip Ruiz; David S Pisetsky
Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice.
Clinical immunology and immunopathology 1992;64(2):166-72.
1992: C R Robertson; Gary S Gilkeson; Michael M Ward; David S Pisetsky
Patterns of heavy and light chain utilization in the antibody response to single-stranded bacterial DNA in normal human subjects and patients with systemic lupus erythematosus.
Clinical immunology and immunopathology 1992;62(1 Pt 1):25-32.
1991: J P Messina; Gary S Gilkeson; David S Pisetsky
Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(6):1759-64.
1991: Gary S Gilkeson; Phillip Ruiz; A J Pritchard; David S Pisetsky
Genetic control of inflammatory arthritis and glomerulonephritis in congenic lpr mice and their F1 hybrids.
Journal of autoimmunity 1991;4(4):595-606.
1991: Gary S Gilkeson; A J Pritchard; David S Pisetsky
Specificity of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA.
Clinical immunology and immunopathology 1991;59(2):288-300.
1990: D P Wu; Gary S Gilkeson; J Armitage; C F Reich; David S Pisetsky
Selective recognition of DNA antigenic determinants by murine monoclonal anti-DNA antibodies.
Clinical and experimental immunology 1990;82(1):33-7.
1990: Gary S Gilkeson; A J Pritchard; David S Pisetsky
Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA.
European journal of immunology 1990;20(8):1789-94.
1990: F Blum; Gary S Gilkeson; C Greenberg; J Murray
Superficial migratory thrombophlebitis and the lupus anticoagulant.
International journal of dermatology 1990;29(3):190-2.
1990: David S Pisetsky; J P Grudier; Gary S Gilkeson
A role for immunogenic DNA in the pathogenesis of systemic lupus erythematosus.
Arthritis and rheumatism 1990;33(2):153-9.
1989: Gary S Gilkeson; Phillip Ruiz; J P Grudier; Roger Kurlander; David S Pisetsky
Genetic control of inflammatory arthritis in congenic lpr mice.
Clinical immunology and immunopathology 1989;53(3):460-74.
1989: Gary S Gilkeson; J P Grudier; David S Pisetsky
The antibody response of normal mice to immunization with single-stranded DNA of various species origin.
Clinical immunology and immunopathology 1989;51(3):362-71.
1989: Gary S Gilkeson; C W Christensen; J R Rice
Retroperitoneal fibrosis. The forgotten connective tissue disease.
North Carolina medical journal 1989;50(4):192-4.
1989: Gary S Gilkeson; J P Grudier; D G Karounos; David S Pisetsky
Induction of anti-double stranded DNA antibodies in normal mice by immunization with bacterial DNA.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(5):1482-6.
1988: W J Shergy; Gary S Gilkeson; D C German
Acute gouty arthritis and intravenous nitroglycerin.
Archives of internal medicine 1988;148(11):2505-6.
1988: Gary S Gilkeson; R Polisson; H Sinclair; J Vogler; J Rice; D Caldwell; Charles E Spritzer; Salutario Martinez
Early detection of carpal erosions in patients with rheumatoid arthritis: a pilot study of magnetic resonance imaging.
The Journal of rheumatology 1988;15(9):1361-6.
1988: Gary S Gilkeson; D S Caldwell
Riboflavin-responsive multiple acyl coenzyme A dehydrogenase deficiency presenting as a proximal myopathy in a young adult.
Arthritis and rheumatism 1988;31(5):695-6.
1987: Gary S Gilkeson; R L Delaney
Effectiveness of sublingual clonidine in patients unable to take oral medication.
Drug intelligence & clinical pharmacy 1987;21(3):262-3.
1978: Gary S Gilkeson; M J Stone; M Waterman; R Ting; C E Gomez-Sanchez; A Hull; J T Willerson
Detection of myoglobin by radioimmmunoassay in human sera: its usefulness and limitations as an emergency room screening test for acute myocardial infarction.
American heart journal 1978;95(1):70-7.