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Daniel Gillet

Research Profile

Chemicals & Drugs

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Cell Membrane

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TOP 3
Romain Noel; Valérie Pons; Julien Barbier; David-Alexandre Buisson; Maria Daniela Garcia-Castillo; Daniel Gillet; Amélie Goudet; Neetu Gupta; Ludger Johannes; Jennifer Martinez; Aurélien Michau; Jean-Christophe Cintrat
N-Methyldihydroquinazolinone Derivatives of Retro-2 with Enhanced Efficacy against Shiga Toxin.
Xin Ming; Romain Noel; Julien Barbier; John Bauman; Canhong Cao; Kyle Carver; Jean-Christophe Cintrat; Michael Fisher; Daniel Gillet; Rudolph L Juliano
The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides.
Alexandre Chenal; Christine Almunia; Clément E Blanchet; Patrice Catty; Elisabeth Garcia; Daniel Gillet; Alexis Gonneaud; Nicolas Hussy; Johanna C Karst; Christel Marquette; Sylvain Pichard; Bénédicte Salin; Charlotte Vendrely; Heidi Vitrac; Vincent Forge
Amyloid fibrils formed by the programmed cell death regulator Bcl-xL.

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All Publications

2013: Romain Noel; Valérie Pons; Julien Barbier; David-Alexandre Buisson; Maria Daniela Garcia-Castillo; Daniel Gillet; Amélie Goudet; Neetu Gupta; Ludger Johannes; Jennifer Martinez; Aurélien Michau; Jean-Christophe Cintrat
N-Methyldihydroquinazolinone Derivatives of Retro-2 with Enhanced Efficacy against Shiga Toxin.
Journal of medicinal chemistry 2013;56(8):3404-13.
2013: Xin Ming; Romain Noel; Julien Barbier; John Bauman; Canhong Cao; Kyle Carver; Jean-Christophe Cintrat; Michael Fisher; Daniel Gillet; Rudolph L Juliano
The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides.
Nucleic acids research 2013;41(6):3673-87.
2012: Alexandre Chenal; Christine Almunia; Clément E Blanchet; Patrice Catty; Elisabeth Garcia; Daniel Gillet; Alexis Gonneaud; Nicolas Hussy; Johanna C Karst; Christel Marquette; Sylvain Pichard; Bénédicte Salin; Charlotte Vendrely; Heidi Vitrac; Vincent Forge
Amyloid fibrils formed by the programmed cell death regulator Bcl-xL.
Journal of molecular biology 2012;415(3):584-99.
2012: Julien Barbier; Céline Bouclier; Ludger Johannes; Daniel Gillet
Inhibitors of the cellular trafficking of ricin.
Toxins 2012;4(1):15-27.
2011: Anne Chassaing; Vincent Forge; Anne Araye-Guet; Julien Barbier; Sylvain Pichard; Daniel Gillet
Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain.
The FEBS journal 2011;278(23):4516-25.
2011: Petr Man; Caroline Montagner; Sylvain Pichard; Heidi Vitrac; Eric Forest; Daniel Gillet; Daniel Kavan; Vincent Forge
Accessibility changes within diphtheria toxin T domain upon membrane penetration probed by hydrogen exchange and mass spectrometry.
Journal of molecular biology 2011;414(1):123-34.
2010: Petr Man; Caroline Montagner; Heidi Vitrac; Daniel Kavan; Sylvain Pichard; Daniel Gillet; Eric Forest; Vincent Forge
Accessibility changes within diphtheria toxin T domain when in the functional molten globule state, as determined using hydrogen/deuterium exchange measurements.
The FEBS journal 2010;277(3):653-62.
2009: Alexandre Chenal; Lydia Prongidi-Fix; Aurélie Perier; Christopher Aisenbrey; Grégory Vernier; Stephan Lambotte; Michael Haertlein; Marie-Thérèse Dauvergne; Giovanna Fragneto; Burkhard Bechinger; Daniel Gillet; Vincent Forge; Michel Ferrand
Deciphering membrane insertion of the diphtheria toxin T domain by specular neutron reflectometry and solid-state NMR spectroscopy.
Journal of molecular biology 2009;391(5):872-83.
2007: Aurélie Perier; Christine Gourier; Sylvain Pichard; Julien Husson; Evelyne Lajeunesse; Aurélie Babon; André Menez; Daniel Gillet
Creation of intercellular bonds by anchoring protein ligands to membranes using the diphtheria toxin T domain.
FEBS letters 2007;581(28):5480-4.
2007: Aurélie Perier; Anne Chassaing; Stéphanie Raffestin; Sylvain Pichard; Michel Masella; André Ménez; Vincent Forge; Alexandre Chenal; Daniel Gillet
Concerted protonation of key histidines triggers membrane interaction of the diphtheria toxin T domain.
The Journal of biological chemistry 2007;282(33):24239-45.
2007: Caroline Montagner; Aurélie Perier; Sylvain Pichard; Grégory Vernier; André Ménez; Daniel Gillet; Vincent Forge; Alexandre Chenal
Behavior of the N-terminal helices of the diphtheria toxin T domain during the successive steps of membrane interaction.
Biochemistry 2007;46(7):1878-87.
2006: Bratislav Janjic; Pedro Andrade; Xiao-Fei Wang; Julien Fourcade; Christine Almunia; Pavol Kudela; Adam Brufsky; Samuel Jacobs; David M Friedland; Ronald G Stoller; Daniel Gillet; Ronald Herberman; John M Kirkwood; Bernard Maillere; Hassane M Zarour
Spontaneous CD4+ T cell responses against TRAG-3 in patients with melanoma and breast cancers.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(4):2717-27.
2005: Alexandre Chenal; Grégory Vernier; Philippe Savarin; Natalia A Bushmarina; Annabelle Gèze; Florent Guillain; Daniel Gillet; Vincent Forge
Conformational states and thermodynamics of alpha-lactalbumin bound to membranes: a case study of the effects of pH, calcium, lipid membrane curvature and charge.
Journal of molecular biology 2005;349(4):890-905.
2005: Aurélie Babon; Christine Almunia; Claire Boccaccio; Bruno Beaumelle; Michael H Gelb; André Ménez; Bernard Maillère; Jean-Pierre Abastado; Margarita Salcedo; Daniel Gillet
Cross-presentation of a CMV pp65 epitope by human dendritic cells using bee venom PLA2 as a membrane-binding vector.
FEBS letters 2005;579(7):1658-64.
2005: Maja Mandic; Florence A Castelli; Bratislav Janjic; Christine Almunia; Pedro Andrade; Daniel Gillet; Vladimir Brusic; John M Kirkwood; Bernard Maillere; Hassane M Zarour
One NY-ESO-1-derived epitope that promiscuously binds to multiple HLA-DR and HLA-DP4 molecules and stimulates autologous CD4+ T cells from patients with NY-ESO-1-expressing melanoma.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1751-9.
2004: Cécile Buhot; Alexandre Chenal; Alain Sanson; Sandra Pouvelle-Moratille; Michael H Gelb; André Ménez; Daniel Gillet; Bernard Maillère
Alteration of the tertiary structure of the major bee venom allergen Api m 1 by multiple mutations is concomitant with low IgE reactivity.
Protein science : a publication of the Protein Society 2004;13(11):2970-8.
2004: Mahmood Tavallaie; Alexandre Chenal; Daniel Gillet; Yannick PEREIRA; Maria Manich; Maryse Gibert; Stéphanie Raffestin; Michel R Popoff; Jean-Christophe Marvaud
Interaction between the two subdomains of the C-terminal part of the botulinum neurotoxin A is essential for the generation of protective antibodies.
FEBS letters 2004;572(1-3):299-306.
2003: Maja Mandic; Christine Almunia; Stephanie Vicel; Daniel Gillet; Bratislav Janjic; Kara Coval; Bernard Maillere; John M Kirkwood; Hassane M Zarour
The alternative open reading frame of LAGE-1 gives rise to multiple promiscuous HLA-DR-restricted epitopes recognized by T-helper 1-type tumor-reactive CD4+ T cells.
Cancer research 2003;63(19):6506-15.
2003: Philippe Nizard; David-Alexandre Gross; Aurélie Babon; Alexandre Chenal; Bruno Beaumelle; Kostas Kosmatopoulos; Daniel Gillet
Anchoring cytokines to tumor cells for the preparation of anticancer vaccines without gene transfection in mice.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2003;26(1):63-71.
2002: Jean-Christophe Marvaud; Bradley G Stiles; Alexandre Chenal; Daniel Gillet; Maryse Gibert; Leonard A Smith; Michel R Popoff
Clostridium perfringens iota toxin. Mapping of the Ia domain involved in docking with Ib and cellular internalization.
The Journal of biological chemistry 2002;277(46):43659-66.
2002: Alexandre Chenal; Philippe Savarin; Philippe Nizard; Florent Guillain; Daniel Gillet; Vincent Forge
Membrane protein insertion regulated by bringing electrostatic and hydrophobic interactions into play. A case study with the translocation domain of diphtheria toxin.
The Journal of biological chemistry 2002;277(45):43425-32.
2002: Alexandre Chenal; Philippe Nizard; Vincent Forge; Martine Pugnière; Marie-Odile Roy; Jean-Claude Mani; Florent Guillain; Daniel Gillet
Does fusion of domains from unrelated proteins affect their folding pathways and the structural changes involved in their function? A case study with the diphtheria toxin T domain.
Protein engineering 2002;15(5):383-91.
2001: Philippe Nizard; Alexandre Chenal; Bruno Beaumelle; A Fourcade; Daniel Gillet
Prolonged display or rapid internalization of the IgG-binding protein ZZ anchored to the surface of cells using the diphtheria toxin T domain.
Protein engineering 2001;14(6):439-46.
2001: Philippe Nizard; David-Alexandre Gross; Alexandre Chenal; Bruno Beaumelle; Kostas Kosmatopoulos; Daniel Gillet
[Anchoring cytokines to cancer cells using diphtheria toxin: better than immunotherapy by gene transfer?].
Journal de la Société de biologie 2001;195(3):229-34.
1998: D Liger; Philippe Nizard; C Gaillard; Johanna C vanderSpek; John R Murphy; B Pitard; Daniel Gillet
The diphtheria toxin transmembrane domain as a pH sensitive membrane anchor for human interleukin-2 and murine interleukin-3.
Protein engineering 1998;11(11):1111-20.
1998: Philippe Nizard; D Liger; C Gaillard; Daniel Gillet
Anchoring antibodies to membranes using a diphtheria toxin T domain-ZZ fusion protein as a pH sensitive membrane anchor.
FEBS letters 1998;433(1-2):83-8.
1997: Laetitia Petit; Maryse Gibert; Daniel Gillet; Christine Laurent-Winter; Patrice Boquet; Michel R Popoff
Clostridium perfringens epsilon-toxin acts on MDCK cells by forming a large membrane complex.
Journal of bacteriology 1997;179(20):6480-7.
1997: D Liger; Johanna C vanderSpek; C Gaillard; C Cansier; John R Murphy; P Leboulch; Daniel Gillet
Characterization and receptor specific toxicity of two diphtheria toxin-related interleukin-3 fusion proteins DAB389-mIL-3 and DAB389-(Gly4Ser)2-mIL-3.
FEBS letters 1997;406(1-2):157-61.
1994: Eric Ezan; Frédéric Ducancel; Daniel Gillet; Pascal Drevet; André Ménez; JM Grognet; Jean-Claude Boulain
Recombinant technology in the preparation of immunogen and enzymatic tracer. Application to the development of an enzyme immunoassay for rat prolactin.
Journal of immunological methods 1994;169(2):205-11.
1993: Daniel Gillet; Eric Ezan; Frédéric Ducancel; C Gaillard; T Ardouin; M Istin; André Ménez; Jean-Claude Boulain; JM Grognet
Enzyme immunoassay using a rat prolactin-alkaline phosphatase recombinant tracer.
Analytical chemistry 1993;65(13):1779-84.
1993: Frédéric Ducancel; Daniel Gillet; A Carrier; Evelyne Lajeunesse; André Ménez; Jean-Claude Boulain
Recombinant colorimetric antibodies: construction and characterization of a bifunctional F(ab)2/alkaline phosphatase conjugate produced in Escherichia coli.
Bio/technology (Nature Publishing Company) 1993;11(5):601-5.
1992: Beata Schlichtholz; Y Legros; Daniel Gillet; C Gaillard; Michel Marty; D Lane; F Calvo; T Soussi
The immune response to p53 in breast cancer patients is directed against immunodominant epitopes unrelated to the mutational hot spot.
Cancer research 1992;52(22):6380-4.
1992: Daniel Gillet; Frédéric Ducancel; E Pradel; Michel Léonetti; André Ménez; Jean-Claude Boulain
Insertion of a disulfide-containing neurotoxin into E. coli alkaline phosphatase: the hybrid retains both biological activities.
Protein engineering 1992;5(3):273-8.
1992: Frédéric Ducancel; Daniel Gillet; André Ménez; Jean-Claude Boulain
[Recombinant colorimetric antibodies: genetic construction and production in E. coli].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1992;315(6):221-4.