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Alfred Gilman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
18
Sternweis, Paul
17
Sprang, Stephen
14
Kozasa, Tohru
11
Mumby, Susanne
10
Sunahara, Roger
10
Tesmer, John
9
Lee, Ethan
9
Dessauer, Carmen
8
Linder, Maurine
7
Hepler, John
6
Kahn, Richard
6
Berman, David
6
Krumins, Andrejs
5
Ross, Elliott
5
Coleman, DE

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Publications

TOP 3
Krumins Andrejs M; Gilman Alfred G
Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins.
Gibson Scott K; Gilman Alfred G
Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.
Tall Gregory G; Gilman Alfred G
Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes.

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All Publications

2006: Krumins Andrejs M; Gilman Alfred G
Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins.
The Journal of biological chemistry 2006;281(15):10250-62.
2006: Gibson Scott K; Gilman Alfred G
Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(1):212-7.
2005: Tall Gregory G; Gilman Alfred G
Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16584-9.
2004: Tall Gregory G; Gilman Alfred G
Purification and functional analysis of Ric-8A: a guanine nucleotide exchange factor for G-protein alpha subunits.
Methods in enzymology 2004;390():377-88.
2003: Hatley Mark E; Lockless Steve W; Gibson Scott K; Gilman Alfred G; Ranganathan Rama
Allosteric determinants in guanine nucleotide-binding proteins.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):14445-50.
2003: Chen Zhu; Raman Malavika; Chen Linda; Lee Sheu Fen; Gilman Alfred G; Cobb Melanie H
TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors.
The Journal of biological chemistry 2003;278(25):22278-83.
2003: Tall Gregory G; Krumins Andrejs M; Gilman Alfred G
Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor.
The Journal of biological chemistry 2003;278(10):8356-62.
2002: Gilman Alfred G; Simon Melvin I; Bourne Henry R; Harris Bruce A; Long Rochelle; Ross Elliott M; Stull James T; Taussig Ronald; Bourne Henry R; Arkin Adam P; Cobb Melanie H; Cyster Jason G; Devreotes Peter N; Ferrell James E; Fruman David; Gold Michael; Weiss Arthur; Stull James T; Berridge Michael J; Cantley Lewis C; Catterall William A; Coughlin Shaun R; Olson Eric N; Smith Temple F; Brugge Joan S; Botstein David; Dixon Jack E; Hunter Tony; Lefkowitz Robert J; Pawson Anthony J; Sternberg Paul W; Varmus Harold; Subramaniam Shankar; Sinkovits Robert S; Li Joshua; Mock Dennis; Ning Yuhong; Saunders Brian; Sternweis Paul C; Hilgemann Donald; Scheuermann Richard H; DeCamp Dianne; Hsueh Robert; Lin Keng-Mean; Ni Yan; Seaman William E; Simpson Paul C; O'Connell Timothy D; Roach Tamara; Simon Melvin I; Choi Sangdun; Eversole-Cire Pamela; Fraser Iain; Mumby Marc C; Zhao Yingming; Brekken Deirdre; Shu Hongjun; Meyer Tobias; Chandy Grischa; Heo Won Do; Liou Jen; O'Rourke Nancy; Verghese Mary; Mumby Susanne M; Han Heping; Brown H Alex; Forrester Jeffrey S; Ivanova Pavlina; Milne Stephen B; Casey Patrick J; Harden T Kendall; Arkin Adam P; Doyle John; Gray Martha L; Meyer Tobias; Michnick Stephen; Schmidt Martin A; Toner Mehmet; Tsien Roger Y; Natarajan Madhusudan; Ranganathan Rama; Sambrano Gilberto R;
Overview of the Alliance for Cellular Signaling.
Nature 2002;420(6916):703-6.
2002: Duncan Joseph A; Gilman Alfred G
Characterization of Saccharomyces cerevisiae acyl-protein thioesterase 1, the enzyme responsible for G protein alpha subunit deacylation in vivo.
The Journal of biological chemistry 2002;277(35):31740-52.
2002: Krumins Andrejs M; Gilman Alfred G
Assay of RGS protein activity in vitro using purified components.
Methods in enzymology 2002;344():673-85.
2002: Tesmer John J G; Sunahara Roger K; Fancy David A; Gilman Alfred G; Sprang Stephen R
Crystallization of complex between soluble domains of adenylyl cyclase and activated Gs alpha.
Methods in enzymology 2002;345():198-206.
2002: Hatley Mark E; Gilman Alfred G; Sunahara Roger K
Expression, purification, and assay of cytosolic (catalytic) domains of membrane-bound mammalian adenylyl cyclases.
Methods in enzymology 2002;345():127-40.
2001: Gilman A G
Cross talk: interview with Al Gilman.
Molecular interventions 2001;1(1):14-21.
2000: Hatley M E; Benton B K; Xu J; Manfredi J P; Gilman A G; Sunahara R K
Isolation and characterization of constitutively active mutants of mammalian adenylyl cyclase.
The Journal of biological chemistry 2000;275(49):38626-32.
2000: Gilman A G
Wrong signals about alliance's scope and aim.
Nature 2000;408(6809):133.
2000: Tesmer J J; Dessauer C W; Sunahara R K; Murray L D; Johnson R A; Gilman A G; Sprang S R
Molecular basis for P-site inhibition of adenylyl cyclase.
Biochemistry 2000;39(47):14464-71.
1999: Carman C V; Parent J L; Day P W; Pronin A N; Sternweis P M; Wedegaertner P B; Gilman A G; Benovic J L; Kozasa T
Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2.
The Journal of biological chemistry 1999;274(48):34483-92.
1999: Posner B A; Gilman A G; Harris B A
Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways.
The Journal of biological chemistry 1999;274(43):31087-93.
1999: Chen L T; Gilman A G; Kozasa T
A candidate target for G protein action in brain.
The Journal of biological chemistry 1999;274(38):26931-8.
1999: Tesmer J J; Sunahara R K; Johnson R A; Gosselin G; Gilman A G; Sprang S R
Two-metal-Ion catalysis in adenylyl cyclase.
Science (New York, N.Y.) 1999;285(5428):756-60.
1999: Posner B A; Mukhopadhyay S; Tesmer J J; Gilman A G; Ross E M
Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue.
Biochemistry 1999;38(24):7773-9.
1999: Dessauer C W; Tesmer J J; Sprang S R; Gilman A G
The interactions of adenylate cyclases with P-site inhibitors.
Trends in pharmacological sciences 1999;20(5):205-10.
1999: Huang C; Duncan J A; Gilman A G; Mumby S M
Persistent membrane association of activated and depalmitoylated G protein alpha subunits.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(2):412-7.
1998: Snow B E; Krumins A M; Brothers G M; Lee S F; Wall M A; Chung S; Mangion J; Arya S; Gilman A G; Siderovski D P
A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):13307-12.
1998: Panchenko M P; Saxena K; Li Y; Charnecki S; Sternweis P M; Smith T F; Gilman A G; Kozasa T; Neer E J
Sites important for PLCbeta2 activation by the G protein betagamma subunit map to the sides of the beta propeller structure.
The Journal of biological chemistry 1998;273(43):28298-304.
1998: Dessauer C W; Tesmer J J; Sprang S R; Gilman A G
Identification of a Gialpha binding site on type V adenylyl cyclase.
The Journal of biological chemistry 1998;273(40):25831-9.
1998: Ingi T; Krumins A M; Chidiac P; Brothers G M; Chung S; Snow B E; Barnes C A; Lanahan A A; Siderovski D P; Ross E M; Gilman A G; Worley P F
Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(18):7178-88.
1998: Posner B A; Mixon M B; Wall M A; Sprang S R; Gilman A G
The A326S mutant of Gialpha1 as an approximation of the receptor-bound state.
The Journal of biological chemistry 1998;273(34):21752-8.
1998: Snow B E; Hall R A; Krumins A M; Brothers G M; Bouchard D; Brothers C A; Chung S; Mangion J; Gilman A G; Lefkowitz R J; Siderovski D P
GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain.
The Journal of biological chemistry 1998;273(28):17749-55.
1998: Hart M J; Jiang X; Kozasa T; Roscoe W; Singer W D; Gilman A G; Sternweis P C; Bollag G
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13.
Science (New York, N.Y.) 1998;280(5372):2112-4.
1998: Kozasa T; Jiang X; Hart M J; Sternweis P M; Singer W D; Gilman A G; Bollag G; Sternweis P C
p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13.
Science (New York, N.Y.) 1998;280(5372):2109-11.
1998: Sunahara R K; Beuve A; Tesmer J J; Sprang S R; Garbers D L; Gilman A G
Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases.
The Journal of biological chemistry 1998;273(26):16332-8.
1998: Li Y; Sternweis P M; Charnecki S; Smith T F; Gilman A G; Neer E J; Kozasa T
Sites for Galpha binding on the G protein beta subunit overlap with sites for regulation of phospholipase Cbeta and adenylyl cyclase.
The Journal of biological chemistry 1998;273(26):16265-72.
1998: Duncan J A; Gilman A G
A cytoplasmic acyl-protein thioesterase that removes palmitate from G protein alpha subunits and p21(RAS).
The Journal of biological chemistry 1998;273(25):15830-7.
1998: Lin H C; Duncan J A; Kozasa T; Gilman A G
Sequestration of the G protein beta gamma subunit complex inhibits receptor-mediated endocytosis.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(9):5057-60.
1998: Berman D M; Gilman A G
Mammalian RGS proteins: barbarians at the gate.
The Journal of biological chemistry 1998;273(3):1269-72.
1997: Tesmer J J; Sunahara R K; Gilman A G; Sprang S R
Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.
Science (New York, N.Y.) 1997;278(5345):1907-16.
1997: Huang C; Hepler J R; Chen L T; Gilman A G; Anderson R G; Mumby S M
Organization of G proteins and adenylyl cyclase at the plasma membrane.
Molecular biology of the cell 1997;8(12):2365-78.
1997: Raw A S; Coleman D E; Gilman A G; Sprang S R
Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.
Biochemistry 1997;36(50):15660-9.
1997: Sunahara R K; Tesmer J J; Gilman A G; Sprang S R
Crystal structure of the adenylyl cyclase activator Gsalpha.
Science (New York, N.Y.) 1997;278(5345):1943-7.
1997: Dessauer C W; Gilman A G
The catalytic mechanism of mammalian adenylyl cyclase. Equilibrium binding and kinetic analysis of P-site inhibition.
The Journal of biological chemistry 1997;272(44):27787-95.
1997: Dessauer C W; Scully T T; Gilman A G
Interactions of forskolin and ATP with the cytosolic domains of mammalian adenylyl cyclase.
The Journal of biological chemistry 1997;272(35):22272-7.
1997: Sunahara R K; Dessauer C W; Whisnant R E; Kleuss C; Gilman A G
Interaction of Gsalpha with the cytosolic domains of mammalian adenylyl cyclase.
The Journal of biological chemistry 1997;272(35):22265-71.
1997: Nekrasova E R; Berman D M; Rustandi R R; Hamm H E; Gilman A G; Arshavsky V Y
Activation of transducin guanosine triphosphatase by two proteins of the RGS family.
Biochemistry 1997;36(25):7638-43.
1997: Huang C; Hepler J R; Gilman A G; Mumby S M
Attenuation of Gi- and Gq-mediated signaling by expression of RGS4 or GAIP in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6159-63.
1997: Kleuss C; Gilman A G
Gsalpha contains an unidentified covalent modification that increases its affinity for adenylyl cyclase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6116-20.
1997: Tesmer J J; Berman D M; Gilman A G; Sprang S R
Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis.
Cell 1997;89(2):251-61.
1997: Hepler J R; Berman D M; Gilman A G; Kozasa T
RGS4 and GAIP are GTPase-activating proteins for Gq alpha and block activation of phospholipase C beta by gamma-thio-GTP-Gq alpha.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):428-32.
1996: Dessauer C W; Posner B A; Gilman A G
Visualizing signal transduction: receptors, G-proteins, and adenylate cyclases.
Clinical science (London, England : 1979) 1996;91(5):527-37.
1996: Berghuis A M; Lee E; Raw A S; Gilman A G; Sprang S R
Structure of the GDP-Pi complex of Gly203-->Ala gialpha1: a mimic of the ternary product complex of galpha-catalyzed GTP hydrolysis.
Structure (London, England : 1993) 1996;4(11):1277-90.
1996: Lin H C; Gilman A G
Regulation of dynamin I GTPase activity by G protein betagamma subunits and phosphatidylinositol 4,5-bisphosphate.
The Journal of biological chemistry 1996;271(45):27979-82.
1996: Berman D M; Kozasa T; Gilman A G
The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis.
The Journal of biological chemistry 1996;271(44):27209-12.
1996: Duncan J A; Gilman A G
Autoacylation of G protein alpha subunits.
The Journal of biological chemistry 1996;271(38):23594-600.
1996: Berman D M; Wilkie T M; Gilman A G
GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits.
Cell 1996;86(3):445-52.
1996: Dessauer C W; Gilman A G
Purification and characterization of a soluble form of mammalian adenylyl cyclase.
The Journal of biological chemistry 1996;271(28):16967-74.
1996: Whisnant R E; Gilman A G; Dessauer C W
Interaction of the two cytosolic domains of mammalian adenylyl cyclase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6621-5.
1996: Kozasa T; Gilman A G
Protein kinase C phosphorylates G12 alpha and inhibits its interaction with G beta gamma.
The Journal of biological chemistry 1996;271(21):12562-7.
1996: Schreibmayer W; Dessauer C W; Vorobiov D; Gilman A G; Lester H A; Davidson N; Dascal N
Inhibition of an inwardly rectifying K+ channel by G-protein alpha-subunits.
Nature 1996;380(6575):624-7.
1996: Hepler J R; Biddlecome G H; Kleuss C; Camp L A; Hofmann S L; Ross E M; Gilman A G
Functional importance of the amino terminus of Gq alpha.
The Journal of biological chemistry 1996;271(1):496-504.
1996: Doupnik C A; Dessauer C W; Slepak V Z; Gilman A G; Davidson N; Lester H A
Time resolved kinetics of direct G beta 1 gamma 2 interactions with the carboxyl terminus of Kir3.4 inward rectifier K+ channel subunits.
Neuropharmacology 1996;35(7):923-31.
1996: Sunahara R K; Dessauer C W; Gilman A G
Complexity and diversity of mammalian adenylyl cyclases.
Annual review of pharmacology and toxicology 1996;36():461-80.
1995: Wall M A; Coleman D E; Lee E; Iñiguez-Lluhi J A; Posner B A; Gilman A G; Sprang S R
The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2.
Cell 1995;83(6):1047-58.
1995: Mixon M B; Lee E; Coleman D E; Berghuis A M; Gilman A G; Sprang S R
Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysis.
Science (New York, N.Y.) 1995;270(5238):954-60.
1995: Tang W J; Gilman A G
Construction of a soluble adenylyl cyclase activated by Gs alpha and forskolin.
Science (New York, N.Y.) 1995;268(5218):1769-72.
1995: Gilman A G
Nobel Lecture. G proteins and regulation of adenylyl cyclase.
Bioscience reports 1995;15(2):65-97.
1995: Kozasa T; Gilman A G
Purification of recombinant G proteins from Sf9 cells by hexahistidine tagging of associated subunits. Characterization of alpha 12 and inhibition of adenylyl cyclase by alpha z.
The Journal of biological chemistry 1995;270(4):1734-41.
1995: Taussig R; Gilman A G
Mammalian membrane-bound adenylyl cyclases.
The Journal of biological chemistry 1995;270(1):1-4.
1994: Kleuss C; Raw A S; Lee E; Sprang S R; Gilman A G
Mechanism of GTP hydrolysis by G-protein alpha subunits.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9828-31.
1994: Coleman D E; Berghuis A M; Lee E; Linder M E; Gilman A G; Sprang S R
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.
Science (New York, N.Y.) 1994;265(5177):1405-12.
1994: Chang W J; Ying Y S; Rothberg K G; Hooper N M; Turner A J; Gambliel H A; De Gunzburg J; Mumby S M; Gilman A G; Anderson R G
Purification and characterization of smooth muscle cell caveolae.
The Journal of cell biology 1994;126(1):127-38.
1994: Coleman D E; Lee E; Mixon M B; Linder M E; Berghuis A M; Gilman A G; Sprang S R
Crystallization and preliminary crystallographic studies of Gi alpha 1 and mutants of Gi alpha 1 in the GTP and GDP-bound states.
Journal of molecular biology 1994;238(4):630-4.
1994: Mumby S M; Kleuss C; Gilman A G
Receptor regulation of G-protein palmitoylation.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2800-4.
1994: Wickman K D; Iñiguez-Lluhl J A; Davenport P A; Taussig R; Krapivinsky G B; Linder M E; Gilman A G; Clapham D E
Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel.
Nature 1994;368(6468):255-7.
1994: Ueda N; Iñiguez-Lluhi J A; Lee E; Smrcka A V; Robishaw J D; Gilman A G
G protein beta gamma subunits. Simplified purification and properties of novel isoforms.
The Journal of biological chemistry 1994;269(6):4388-95.
1994: Taussig R; Tang W J; Hepler J R; Gilman A G
Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.
The Journal of biological chemistry 1994;269(8):6093-100.
1994: Hepler J R; Kozasa T; Gilman A G
Purification of recombinant Gq alpha, G11 alpha, and G16 alpha from Sf9 cells.
Methods in enzymology 1994;237():191-212.
1994: Lee E; Linder M E; Gilman A G
Expression of G-protein alpha subunits in Escherichia coli.
Methods in enzymology 1994;237():146-64.
1994: Taussig R; Tang W J; Gilman A G
Expression and purification of recombinant adenylyl cyclases in Sf9 cells.
Methods in enzymology 1994;238():95-108.
1993: Lee S B; Shin S H; Hepler J R; Gilman A G; Rhee S G
Activation of phospholipase C-beta 2 mutants by G protein alpha q and beta gamma subunits.
The Journal of biological chemistry 1993;268(34):25952-7.
1993: Kozasa T; Hepler J R; Smrcka A V; Simon M I; Rhee S G; Sternweis P C; Gilman A G
Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):9176-80.
1993: Iñiguez-Lluhi J; Kleuss C; Gilman A G
The importance of G-protein beta lambda subunits.
Trends in cell biology 1993;3(7):230-6.
1993: Taussig R; Iñiguez-Lluhi J A; Gilman A G
Inhibition of adenylyl cyclase by Gi alpha.
Science (New York, N.Y.) 1993;261(5118):218-21.
1993: Hepler J R; Kozasa T; Smrcka A V; Simon M I; Rhee S G; Sternweis P C; Gilman A G
Purification from Sf9 cells and characterization of recombinant Gq alpha and G11 alpha. Activation of purified phospholipase C isozymes by G alpha subunits.
The Journal of biological chemistry 1993;268(19):14367-75.
1993: Linder M E; Middleton P; Hepler J R; Taussig R; Gilman A G; Mumby S M
Lipid modifications of G proteins: alpha subunits are palmitoylated.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3675-9.
1993: Taussig R; Quarmby L M; Gilman A G
Regulation of purified type I and type II adenylylcyclases by G protein beta gamma subunits.
The Journal of biological chemistry 1993;268(1):9-12.
1992: Iñiguez-Lluhi J A; Simon M I; Robishaw J D; Gilman A G
G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma.
The Journal of biological chemistry 1992;267(32):23409-17.
1992: Hepler J R; Gilman A G
G proteins.
Trends in biochemical sciences 1992;17(10):383-7.
1992: Tang W J; Gilman A G
Adenylyl cyclases.
Cell 1992;70(6):869-72.
1992: Linder M E; Gilman A G
G proteins.
Scientific American 1992;267(1):56-61, 64-5.
1992: Taussig R; Sanchez S; Rifo M; Gilman A G; Belardetti F
Inhibition of the omega-conotoxin-sensitive calcium current by distinct G proteins.
Neuron 1992;8(4):799-809.
1992: Lee E; Taussig R; Gilman A G
The G226A mutant of Gs alpha highlights the requirement for dissociation of G protein subunits.
The Journal of biological chemistry 1992;267(2):1212-8.
1992: Muntz K H; Sternweis P C; Gilman A G; Mumby S M
Influence of gamma subunit prenylation on association of guanine nucleotide-binding regulatory proteins with membranes.
Molecular biology of the cell 1992;3(1):49-61.
1992: Tang W J; Iñiguez-Lluhi J A; Mumby S; Gilman A G
Regulation of mammalian adenylyl cyclases by G-protein alpha and beta gamma subunits.
Cold Spring Harbor symposia on quantitative biology 1992;57():135-44.
1991: Tang W J; Gilman A G
Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits.
Science (New York, N.Y.) 1991;254(5037):1500-3.
1991: Gao B N; Gilman A G
Cloning and expression of a widely distributed (type IV) adenylyl cyclase.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10178-82.
1991: Feinstein P G; Schrader K A; Bakalyar H A; Tang W J; Krupinski J; Gilman A G; Reed R R
Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10173-7.
1991: Itoh H; Gilman A G
Expression and analysis of Gs alpha mutants with decreased ability to activate adenylylcyclase.
The Journal of biological chemistry 1991;266(24):16226-31.
1991: Tang W J; Krupinski J; Gilman A G
Expression and characterization of calmodulin-activated (type I) adenylylcyclase.
The Journal of biological chemistry 1991;266(13):8595-603.
1991: Linder M E; Pang I H; Duronio R J; Gordon J I; Sternweis P C; Gilman A G
Lipid modifications of G protein subunits. Myristoylation of Go alpha increases its affinity for beta gamma.
The Journal of biological chemistry 1991;266(7):4654-9.
1991: Higashijima T; Graziano M P; Suga H; Kainosho M; Gilman A G
19F and 31P NMR spectroscopy of G protein alpha subunits. Mechanism of activation by Al3+ and F-.
The Journal of biological chemistry 1991;266(6):3396-401.
1991: Casey P J; Pang I H; Gilman A G
Assay of G-protein beta gamma-subunit complex by catalytic support of ADP-ribosylation of Go alpha.
Methods in enzymology 1991;195():315-21.
1991: Mumby S M; Gilman A G
Synthetic peptide antisera with determined specificity for G protein alpha or beta subunits.
Methods in enzymology 1991;195():215-33.
1991: Linder M E; Gilman A G
Purification of recombinant Gi alpha and Go alpha proteins from Escherichia coli.
Methods in enzymology 1991;195():202-15.
1991: Graziano M P; Freissmuth M; Gilman A G
Purification of recombinant Gs alpha.
Methods in enzymology 1991;195():192-202.
1990: Mumby S M; Casey P J; Gilman A G; Gutowski S; Sternweis P C
G protein gamma subunits contain a 20-carbon isoprenoid.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5873-7.
1990: Linder M E; Ewald D A; Miller R J; Gilman A G
Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli.
The Journal of biological chemistry 1990;265(14):8243-51.
1990: Casey P J; Fong H K; Simon M I; Gilman A G
Gz, a guanine nucleotide-binding protein with unique biochemical properties.
The Journal of biological chemistry 1990;265(4):2383-90.
1990: Mumby S M; Heukeroth R O; Gordon J I; Gilman A G
G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(2):728-32.
1990: Gilman A G
Regulation of adenylyl cyclase by G proteins.
Advances in second messenger and phosphoprotein research 1990;24():51-7.
1989: Freissmuth M; Gilman A G
Mutations of GS alpha designed to alter the reactivity of the protein with bacterial toxins. Substitutions at ARG187 result in loss of GTPase activity.
The Journal of biological chemistry 1989;264(36):21907-14.
1989: Gilman A G
The Albert Lasker Medical Awards. G proteins and regulation of adenylyl cyclase.
JAMA : the journal of the American Medical Association 1989;262(13):1819-25.
1989: Graziano M P; Gilman A G
Synthesis in Escherichia coli of GTPase-deficient mutants of Gs alpha.
The Journal of biological chemistry 1989;264(26):15475-82.
1989: Freissmuth M; Casey P J; Gilman A G
G proteins control diverse pathways of transmembrane signaling.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(10):2125-31.
1989: Krupinski J; Coussen F; Bakalyar H A; Tang W J; Feinstein P G; Orth K; Slaughter C; Reed R R; Gilman A G
Adenylyl cyclase amino acid sequence: possible channel- or transporter-like structure.
Science (New York, N.Y.) 1989;244(4912):1558-64.
1989: Casey P J; Graziano M P; Gilman A G
G protein beta gamma subunits from bovine brain and retina: equivalent catalytic support of ADP-ribosylation of alpha subunits by pertussis toxin but differential interactions with Gs alpha.
Biochemistry 1989;28(2):611-6.
1989: Graziano M P; Freissmuth M; Gilman A G
Expression of Gs alpha in Escherichia coli. Purification and properties of two forms of the protein.
The Journal of biological chemistry 1989;264(1):409-18.
1989: Gilman A G
Transmembrane signaling, G proteins, and adenylyl cyclase.
Harvey lectures 1989;85():153-72.
1988: Mumby S; Pang I H; Gilman A G; Sternweis P C
Chromatographic resolution and immunologic identification of the alpha 40 and alpha 41 subunits of guanine nucleotide-binding regulatory proteins from bovine brain.
The Journal of biological chemistry 1988;263(4):2020-6.
1988: Casey P J; Gilman A G
G protein involvement in receptor-effector coupling.
The Journal of biological chemistry 1988;263(6):2577-80.
1988: Casey P J; Graziano M P; Freissmuth M; Gilman A G
Role of G proteins in transmembrane signaling.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():203-8.
1987: Gao B; Mumby S; Gilman A G
The G protein beta 2 complementary DNA encodes the beta 35 subunit.
The Journal of biological chemistry 1987;262(36):17254-7.
1987: Buss J E; Mumby S M; Casey P J; Gilman A G; Sefton B M
Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(21):7493-7.
1987: Gao B; Gilman A G; Robishaw J D
A second form of the beta subunit of signal-transducing G proteins.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(17):6122-5.
1987: Graziano M P; Casey P J; Gilman A G
Expression of cDNAs for G proteins in Escherichia coli. Two forms of Gs alpha stimulate adenylate cyclase.
The Journal of biological chemistry 1987;262(23):11375-81.
1987: Higashijima T; Ferguson K M; Sternweis P C; Smigel M D; Gilman A G
Effects of Mg2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteins.
The Journal of biological chemistry 1987;262(2):762-6.
1987: Higashijima T; Ferguson K M; Sternweis P C; Ross E M; Smigel M D; Gilman A G
The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins.
The Journal of biological chemistry 1987;262(2):752-6.
1987: Higashijima T; Ferguson K M; Smigel M D; Gilman A G
The effect of GTP and Mg2+ on the GTPase activity and the fluorescent properties of Go.
The Journal of biological chemistry 1987;262(2):757-61.
1987: Gilman A G
G proteins: transducers of receptor-generated signals.
Annual review of biochemistry 1987;56():615-49.
1986: Robishaw J D; Smigel M D; Gilman A G
Molecular basis for two forms of the G protein that stimulates adenylate cyclase.
The Journal of biological chemistry 1986;261(21):9587-90.
1986: Kahn R A; Gilman A G
The protein cofactor necessary for ADP-ribosylation of Gs by cholera toxin is itself a GTP binding protein.
The Journal of biological chemistry 1986;261(17):7906-11.
1986: Ferguson K M; Higashijima T; Smigel M D; Gilman A G
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins.
The Journal of biological chemistry 1986;261(16):7393-9.
1986: Robishaw J D; Russell D W; Harris B A; Smigel M D; Gilman A G
Deduced primary structure of the alpha subunit of the GTP-binding stimulatory protein of adenylate cyclase.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(5):1251-5.
1986: Mumby S M; Kahn R A; Manning D R; Gilman A G
Antisera of designed specificity for subunits of guanine nucleotide-binding regulatory proteins.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(2):265-9.
1985: May D C; Ross E M; Gilman A G; Smigel M D
Reconstitution of catecholamine-stimulated adenylate cyclase activity using three purified proteins.
The Journal of biological chemistry 1985;260(29):15829-33.
1985: Harris B A; Robishaw J D; Mumby S M; Gilman A G
Molecular cloning of complementary DNA for the alpha subunit of the G protein that stimulates adenylate cyclase.
Science (New York, N.Y.) 1985;229(4719):1274-7.
1985: Katada T; Gilman A G; Watanabe Y; Bauer S; Jakobs K H
Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase.
European journal of biochemistry / FEBS 1985;151(2):431-7.
1985: Smigel M D; Ferguson K M; Gilman A G
Control of adenylate cyclase activity by G proteins.
Advances in cyclic nucleotide and protein phosphorylation research 1985;19():103-11.
1984: Bokoch G M; Gilman A G
Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin.
Cell 1984;39(2 Pt 1):301-8.
1984: Hurley J B; Simon M I; Teplow D B; Robishaw J D; Gilman A G
Homologies between signal transducing G proteins and ras gene products.
Science (New York, N.Y.) 1984;226(4676):860-2.
1984: Asano T; Katada T; Gilman A G; Ross E M
Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by beta-adrenergic receptors in reconstituted phospholipid vesicles.
The Journal of biological chemistry 1984;259(15):9351-4.
1984: Kahn R A; Gilman A G
ADP-ribosylation of Gs promotes the dissociation of its alpha and beta subunits.
The Journal of biological chemistry 1984;259(10):6235-40.
1984: Kahn R A; Gilman A G
Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin.
The Journal of biological chemistry 1984;259(10):6228-34.
1984: Katada T; Northup J K; Bokoch G M; Ui M; Gilman A G
The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and guanine nucleotide-dependent hormonal inhibition.
The Journal of biological chemistry 1984;259(6):3578-85.
1984: Katada T; Bokoch G M; Northup J K; Ui M; Gilman A G
The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Properties and function of the purified protein.
The Journal of biological chemistry 1984;259(6):3568-77.
1984: Bokoch G M; Katada T; Northup J K; Ui M; Gilman A G
Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase.
The Journal of biological chemistry 1984;259(6):3560-7.
1984: Gilman A G
G proteins and dual control of adenylate cyclase.
Cell 1984;36(3):577-9.
1984: Katada T; Bokoch G M; Smigel M D; Ui M; Gilman A G
The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and the inhibition of adenylate cyclase in S49 lymphoma cyc- and wild type membranes.
The Journal of biological chemistry 1984;259(6):3586-95.
1984: Manning D R; Fraser B A; Kahn R A; Gilman A G
ADP-ribosylation of transducin by islet-activation protein. Identification of asparagine as the site of ADP-ribosylation.
The Journal of biological chemistry 1984;259(2):749-56.
1984: Gilman A G
Guanine nucleotide-binding regulatory proteins and dual control of adenylate cyclase.
The Journal of clinical investigation 1984;73(1):1-4.
1984: Smigel M; Katada T; Northup J K; Bokoch G M; Ui M; Gilman A G
Mechanisms of guanine nucleotide-mediated regulation of adenylate cyclase activity.
Advances in cyclic nucleotide and protein phosphorylation research 1984;17():1-18.
1983: Northup J K; Smigel M D; Sternweis P C; Gilman A G
The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution of the activated 45,000-dalton (alpha) subunit.
The Journal of biological chemistry 1983;258(18):11369-76.
1983: Northup J K; Sternweis P C; Gilman A G
The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution, activity, and properties of the 35,000-dalton (beta) subunit.
The Journal of biological chemistry 1983;258(18):11361-8.
1983: Bokoch G M; Katada T; Northup J K; Hewlett E L; Gilman A G
Identification of the predominant substrate for ADP-ribosylation by islet activating protein.
The Journal of biological chemistry 1983;258(4):2072-5.
1982: Northup J K; Smigel M D; Gilman A G
The guanine nucleotide activating site of the regulatory component of adenylate cyclase. Identification by ligand binding.
The Journal of biological chemistry 1982;257(19):11416-23.
1982: Sternweis P C; Gilman A G
Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(16):4888-91.
1982: Schleifer L S; Kahn R A; Hanski E; Northup J K; Sternweis P C; Gilman A G
Requirements for cholera toxin-dependent ADP-ribosylation of the purified regulatory component of adenylate cyclase.
The Journal of biological chemistry 1982;257(1):20-3.
1982: Hanski E; Gilman A G
The guanine nucleotide-binding regulatory component of adenylate cyclase in human erythrocytes.
Journal of cyclic nucleotide research 1982;8(5):323-36.
1982: Smigel M D; Northup J K; Gilman A G
Characteristics of the guanine nucleotide-binding regulatory component of adenylate cyclase.
Recent progress in hormone research 1982;38():601-24.
1981: Hanski E; Sternweis P C; Northup J K; Dromerick A W; Gilman A G
The regulatory component of adenylate cyclase. Purification and properties of the turkey erythrocyte protein.
The Journal of biological chemistry 1981;256(24):12911-9.
1981: Sternweis P C; Northup J K; Smigel M D; Gilman A G
The regulatory component of adenylate cyclase. Purification and properties.
The Journal of biological chemistry 1981;256(22):11517-26.
1981: Sternweis P C; Northup J K; Hanski E; Schleifer L S; Smigel M D; Gilman A G
Purification and properties of the regulatory component (G/F) of adenylate cyclase.
Advances in cyclic nucleotide research 1981;14():23-36.
1980: Northup J K; Sternweis P C; Smigel M D; Schleifer L S; Ross E M; Gilman A G
Purification of the regulatory component of adenylate cyclase.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(11):6516-20.
1980: Schleifer L S; Garrison J C; Sternweis P C; Northup J K; Gilman A G
The regulatory component of adenylate cyclase from uncoupled S49 lymphoma cells differs in charge from the wild type protein.
The Journal of biological chemistry 1980;255(7):2641-4.
1980: Howlett A C; Gilman A G
Hydrodynamic properties of the regulatory component of adenylate cyclase.
The Journal of biological chemistry 1980;255(7):2861-6.
1980: Ross E M; Gilman A G
Biochemical properties of hormone-sensitive adenylate cyclase.
Annual review of biochemistry 1980;49():533-64.
1979: Sternweis P C; Gilman A G
Reconstitution of catecholamine-sensitive adenylate cyclase. Reconstitution of the uncoupled variant of the S40 lymphoma cell.
The Journal of biological chemistry 1979;254(9):3333-40.
1979: Howlett A C; Sternweis P C; Macik B A; Van Arsdale P M; Gilman A G
Reconstitution of catecholamine-sensitive adenylate cyclase. Association of a regulatory component of the enzyme with membranes containing the catalytic protein and beta-adrenergic receptors.
The Journal of biological chemistry 1979;254(7):2287-95.
1979: Ross E M; Howlett A C; Gilman A G
Identification and partial characterization of some components of hormone-stimulated adenylate cyclase.
Progress in clinical and biological research 1979;31():735-49.
1978: Ross E M; Howlett A C; Ferguson K M; Gilman A G
Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.
The Journal of biological chemistry 1978;253(18):6401-12.
1978: Howlett A C; Van Arsdale P M; Gilman A G
Efficiency of coupling between the beta adrenergic receptor and adenylate cyclase.
Molecular pharmacology 1978;14(4):531-9.
1978: Burgess W H; Howlett A C; Kretsinger R H; Gilman A G
S49 lymphoma wild type and variant clones contain normal calcium dependent regulator.
Journal of cyclic nucleotide research 1978;4(3):175-81.
1978: Ross E M; Haga T; Howlett A C; Schwarzmeier J; Schleifer L S; Gilman A G
Hormone-sensitive adenylate cyclase: resolution and reconstitution of some components necessary for regulation of the enzyme.
Advances in cyclic nucleotide research 1978;9():53-68.
1977: Ross E M; Gilman A G
Resolution of some components of adenylate cyclase necessary for catalytic activity.
The Journal of biological chemistry 1977;252(20):6966-9.
1977: Ross E M; Gilman A G
Reconstitution of catecholamine-sensitive adenylate cyclase activity: interactions of solubilized components with receptor-replete membranes.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(9):3715-9.
1977: Ross E M; Maguire M E; Sturgill T W; Biltonen R L; Gilman A G
Relationship between the beta-adrenergic receptor and adenylate cyclase.
The Journal of biological chemistry 1977;252(16):5761-75.
1977: Haga T; Ross E M; Anderson H J; Gilman A G
Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(5):2016-20.
1977: Maguire M E; Ross E M; Gilman A G
beta-Adrenergic receptor: ligand binding properties and the interaction with adenylyl cyclase.
Advances in cyclic nucleotide research 1977;8():1-83.
1976: Insel P A; Maguire M E; Gilman A G; Bourne H R; Coffino P; Melmon K L
Beta adrenergic receptors and adenylate cyclase: products of separate genes?
Molecular pharmacology 1976;12(6):1062-9.
1976: Brunton L L; Wiklund R A; Van Arsdale P M; Gilman A G
Binding of (3H)prostaglandin E1 to putative receptors linked to adenylate cyclase of cultured cell clones.
The Journal of biological chemistry 1976;251(10):3037-44.
1976: Maguire M E; Wiklund R A; Anderson H J; Gilman A G
Binding of (125I)iodohydroxybenzylpindolol to putative beta-adrenergic receptors of rat glioma cells and other cell clones.
The Journal of biological chemistry 1976;251(5):1221-31.
1976: Maguire M E; Van Arsdale P M; Gilman A G
An agonist-specific effect of guanine nucleotides on binding to the beta adrenergic receptor.
Molecular pharmacology 1976;12(2):335-9.
1976: Maguire M E; Brunton L L; Wiklund R A; Anderson H I; Van Arsdale P M; Gilman A G
Hormone receptors and the control of cyclic AMP metabolism in parental and hybrid somatic cells.
Recent progress in hormone research 1976;32():633-67.
1975: Maguire M E; Sturgill T W; Gilman A G
Frustration and adenylate cyclase.
Metabolism: clinical and experimental 1975;24(3):287-99.
1975: Maguire M E; Sturgill T W; Anderson H J; Minna J D; Gilman A G
Hormonal control of cyclic AMP metabolism in parental and hybrid somatic cells.
Advances in cyclic nucleotide research 1975;5():699-718.
1974: Guerrant R L; Brunton L L; Schnaitman T C; Rebhun L I; Gilman A G
Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli.
Infection and immunity 1974;10(2):320-7.
1974: Maguire M E; Gilman A G
Adenylate cyclase assay with adenylyl imidodiphosphate and product detection by competitive protein binding.
Biochimica et biophysica acta 1974;358(1):154-63.
1974: Gilman A G; Murad F
Assay of cyclic nucleotides by receptor protein binding displacement.
Methods in enzymology 1974;38():49-61.
1973: Minna J D; Gilman A G
Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. II. Effects of prostaglandin E1 and theophylline on parental and hybrid cells.
The Journal of biological chemistry 1973;248(19):6618-25.
1973: Gilman A G; Minna J D
Expression of genes for metabolism of cyclic adenosine 3':5'-monophosphate in somatic cells. I. Responses to catecholamines in parental and hybrid cells.
The Journal of biological chemistry 1973;248(19):6610-7.
1972: Gilman A G; Schrier B K
Adenosine cyclic 3',5'-monophosphate in fetal rat brain cell cultures. I. Effect of catecholamines.
Molecular pharmacology 1972;8(4):410-6.
1972: Secrist J A; Barrio J R; Leonard N J; Villar-Palasi C; Gilman A G
Fluorescent modification of adenosine 3',5'-monophosphate: spectroscopic properties and activity in enzyme systems.
Science (New York, N.Y.) 1972;177(45):279-80.
1972: Gilman A G
Regulation of cyclic AMP metabolism in cultured cells of the nervous system.
Advances in cyclic nucleotide research 1972;1():389-410.
1972: Gilman A G
Protein binding assays for cyclic nucleotides.
Advances in cyclic nucleotide research 1972;2():9-24.
1971: Gilman A G; Nirenberg M
Regulation of adenosine 3',5'-cyclic monophosphate metabolism in cultured neuroblastoma cells.
Nature 1971;234(5328):356-8.
1971: Murad F; Gilman A G
Adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate: a simultaneous protein binding assay.
Biochimica et biophysica acta 1971;252(2):397-400.
1971: Seeds N W; Gilman A G
Norepinephrine stinulated increase of cyclic AMP levels in developing mouse brain cell cultures.
Science (New York, N.Y.) 1971;174(6):292.
1971: Gilman A G; Nirenberg M
Effect of catecholamines on the adenosine 3':5'-cyclic monophosphate concentrations of clonal satellite cells of neurons.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(9):2165-8.
1970: Gilman A G
A protein binding assay for adenosine 3':5'-cyclic monophosphate.
Proceedings of the National Academy of Sciences of the United States of America 1970;67(1):305-12.
1970: Seeds N W; Gilman A G; Amano T; Nirenberg M W
Regulation of axon formation by clonal lines of a neural tumor.
Proceedings of the National Academy of Sciences of the United States of America 1970;66(1):160-7.
1968: Gilman A G; Rall T W
The role of adenosine 3',5'-phosphate in mediating effects of thyroid-stimulating hormone on carbohydrate metabolism of bovine thyroid slices.
The Journal of biological chemistry 1968;243(22):5872-81.
1968: Gilman A G; Rall T W
Factors influencing adenosine 3',5'-phosphate accumulation in bovine thyroid slices.
The Journal of biological chemistry 1968;243(22):5867-71.

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