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Bernard Gilquin

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

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Chemicals & Drugs

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Publications

TOP 3
Emeric Gueneau; Marie-Hélene Le Du; Pierre Legrand; Floriana Londino; Josan A Márquez; Mireille Moutiez; Cathy Quemener; Carine Tellier-Lebegue; Serge Boiteux; Pierre Bonnesoeur; Claudine Dherin; Bernard Gilquin; Muriel Gondry; Jean-Baptiste Charbonnier
Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Catherine Marquer; André Ménez; Gilles Mourier; Denis Servent; Sophie Zinn-Justin; Carole Fruchart-Gaillard; Guillaume Letellier; Elodie Marcon; Bernard Gilquin
Structural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptor.
Emilie Kondé; Benjamin Bourgeois; Carine Tellier-Lebegue; Wei Wu; Javier Pérez; Sandrine Caputo; Wika Attanda; Sylvaine Gasparini; Jean-Baptiste Charbonnier; Bernard Gilquin; Howard J Worman; Sophie Zinn-Justin
Structural analysis of the Smad2-MAN1 interaction that regulates transforming growth factor-β signaling at the inner nuclear membrane.

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All Publications

2013: Emeric Gueneau; Marie-Hélene Le Du; Pierre Legrand; Floriana Londino; Josan A Márquez; Mireille Moutiez; Cathy Quemener; Carine Tellier-Lebegue; Serge Boiteux; Pierre Bonnesoeur; Claudine Dherin; Bernard Gilquin; Muriel Gondry; Jean-Baptiste Charbonnier
Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nature structural & molecular biology 2013;20(4):461-8.
2011: Catherine Marquer; André Ménez; Gilles Mourier; Denis Servent; Sophie Zinn-Justin; Carole Fruchart-Gaillard; Guillaume Letellier; Elodie Marcon; Bernard Gilquin
Structural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptor.
The Journal of biological chemistry 2011;286(36):31661-75.
2010: Emilie Kondé; Benjamin Bourgeois; Carine Tellier-Lebegue; Wei Wu; Javier Pérez; Sandrine Caputo; Wika Attanda; Sylvaine Gasparini; Jean-Baptiste Charbonnier; Bernard Gilquin; Howard J Worman; Sophie Zinn-Justin
Structural analysis of the Smad2-MAN1 interaction that regulates transforming growth factor-β signaling at the inner nuclear membrane.
Biochemistry 2010;49(37):8020-32.
2008: Cédric Laguri; Isabelle Duband-Goulet; Nikolas Friedrich; Marianne Axt; Pascal Belin; Isabelle Callebaut; Bernard Gilquin; Sophie Zinn-Justin; Joël Couprie
Human mismatch repair protein MSH6 contains a PWWP domain that targets double stranded DNA.
Biochemistry 2008;47(23):6199-207.
2008: Bernard Gilquin
[The controversy concerning Friedrich Wegener].
Presse médicale (Paris, France : 1983) 2008;37(5 Pt 1):799-801.
2007: Ludovic Carlier; Joël Couprie; Albane le Maire; Laure Guilhaudis; Isabelle Milazzo-Segalas; Marie Courçon; Mireille Moutiez; Muriel Gondry; Daniel Davoust; Bernard Gilquin; Sophie Zinn-Justin
Solution structure of the region 51-160 of human KIN17 reveals an atypical winged helix domain.
Protein science : a publication of the Protein Society 2007;16(12):2750-5.
2007: Nathalie Lancelot; Gaëlle Charier; Joël Couprie; Isabelle Duband-Goulet; Béatrice Alpha-Bazin; Eric Quemeneur; Emilie Ma; Marie-Claude Marsolier-Kergoat; Virginie Ropars; Jean-Baptiste Charbonnier; Simona Miron; Constantin T Craescu; Isabelle Callebaut; Bernard Gilquin; Sophie Zinn-Justin
The checkpoint Saccharomyces cerevisiae Rad9 protein contains a tandem tudor domain that recognizes DNA.
Nucleic acids research 2007;35(17):5898-912.
2006: Henrik Gårdsvoll; Bernard Gilquin; Marie Hélène Le Du; Andre Ménèz; Thomas J D Jørgensen; Michael Ploug
Characterization of the functional epitope on the urokinase receptor. Complete alanine scanning mutagenesis supplemented by chemical cross-linking.
The Journal of biological chemistry 2006;281(28):19260-72.
2006: Sandrine Caputo; Joël Couprie; Isabelle Duband-Goulet; Emilie Kondé; Feng Lin; Sandrine Braud; Muriel Gondry; Bernard Gilquin; Howard J Worman; Sophie Zinn-Justin
The carboxyl-terminal nucleoplasmic region of MAN1 exhibits a DNA binding winged helix domain.
The Journal of biological chemistry 2006;281(26):18208-15.
2006: Ludovic Carlier; Albane le Maire; Sandrine Braud; Cédric Masson; Muriel Gondry; Sophie Zinn-Justin; Laure Guilhaudis; Isabelle Milazzo; Daniel Davoust; Bernard Gilquin; Joël Couprie
NMR assignment of region 51-160 of human KIN17, a DNA and RNA-binding protein.
Journal of biomolecular NMR 2006;36 Suppl 1():29.
2006: Sandrine Caputo; Feng Lin; Bernard Gilquin; Howard J Worman; Sophie Zinn-Justin; Joël Couprie
NMR assignment of region 655-775 of human MAN1.
Journal of biomolecular NMR 2006;36 Suppl 1():2.
2005: Bernard Gilquin; Sandrine Braud; Mats A L Eriksson; Benoît Roux; Timothy D Bailey; Birgit T Priest; Maria L Garcia; André Ménez; Sylvaine Gasparini
A variable residue in the pore of Kv1 channels is critical for the high affinity of blockers from sea anemones and scorpions.
The Journal of biological chemistry 2005;280(29):27093-102.
2005: Béatrice Alpha-Bazin; Alain Lorphelin; Nathalie Nozerand; Gaëlle Charier; Charles Marchetti; Frédéric Bérenguer; Joël Couprie; Bernard Gilquin; Sophie Zinn-Justin; Eric Quemeneur
Boundaries and physical characterization of a new domain shared between mammalian 53BP1 and yeast Rad9 checkpoint proteins.
Protein science : a publication of the Protein Society 2005;14(7):1827-39.
2005: Paola Llinas; Marie Hélène Le Du; Henrik Gårdsvoll; Keld Danø; Michael Ploug; Bernard Gilquin; Enrico A Stura; André Ménez
Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide.
The EMBO journal 2005;24(9):1655-63.
2005: Simone Spuler; Christian Geier; Karl Josef Osterziel; Matthias Gutberlet; Janine Genschel; Thomas-Nicolas Lehmann; Sophie Zinn-Justin; Bernard Gilquin; Hartmut Schmidt
A new LMNA mutation causing limb girdle muscular dystrophy 1B.
Journal of neurology 2005;252(5):621-3.
2004: Gaëlle Charier; Joël Couprie; Béatrice Alpha-Bazin; Vincent Meyer; Eric Quemeneur; raphael guerois; Isabelle Callebaut; Bernard Gilquin; Sophie Zinn-Justin
The Tudor tandem of 53BP1: a new structural motif involved in DNA and RG-rich peptide binding.
Structure (London, England : 1993) 2004;12(9):1551-62.
2004: Sylvaine Gasparini; Bernard Gilquin; André Ménez
Comparison of sea anemone and scorpion toxins binding to Kv1 channels: an example of convergent evolution.
Toxicon : official journal of the International Society on Toxinology 2004;43(8):901-8.
2004: Gaëlle Charier; Béatrice Alpha-Bazin; Joël Couprie; Isabelle Callebaut; Frédéric Bérenguer; Eric Quemeneur; Bernard Gilquin; Sophie Zinn-Justin
1H, 13C and 15N resonance assignments of the region 1463-1617 of the mouse p53 binding protein 1 (53BP1).
Journal of biomolecular NMR 2004;28(3):303-4.
2003: Bernard Gilquin; Marjorie Bourgoin; Renée Ménez; Marie Hélène Le Du; Denis Servent; Sophie Zinn-Justin; André Ménez
Motions and structural variability within toxins: implication for their use as scaffolds for protein engineering.
Protein science : a publication of the Protein Society 2003;12(2):266-77.
2002: Patrick Barth; Philippe Savarin; Bernard Gilquin; Bernard Lagoutte; Francoise Ochsenbein
Solution NMR structure and backbone dynamics of the PsaE subunit of photosystem I from Synechocystis sp. PCC 6803.
Biochemistry 2002;41(47):13902-14.
2002: Bernard Gilquin; Judith Racapé; Anja Wrisch; Violeta Visan; Alain Lecoq; Stephan Grissmer; André Ménez; Sylvaine Gasparini
Structure of the BgK-Kv1.1 complex based on distance restraints identified by double mutant cycles. Molecular basis for convergent evolution of Kv1 channel blockers.
The Journal of biological chemistry 2002;277(40):37406-13.
2002: Isabelle Krimm; Cecilia Ostlund; Bernard Gilquin; Joël Couprie; Paul Hossenlopp; Jean-Paul Mornon; Gisèle Bonne; Jean-Claude Courvalin; Howard J Worman; Sophie Zinn-Justin
The Ig-like structure of the C-terminal domain of lamin A/C, mutated in muscular dystrophies, cardiomyopathy, and partial lipodystrophy.
Structure (London, England : 1993) 2002;10(6):811-23.
2002: Carole Fruchart-Gaillard; Bernard Gilquin; Stephanie Antil-Delbeke; Nicolas Le Novère; Toru Tamiya; Pierre-Jean Corringer; Jean-Pierre Changeux; André Ménez; Denis Servent
Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):3216-21.
2002: J Iñaki Guijarro; Alessandro Pintar; Ada Prochnicka-Chalufour; Valérie Guez; Bernard Gilquin; Hugues BEDOUELLE; Muriel DELEPIERRE
Structure and dynamics of the anticodon arm binding domain of Bacillus stearothermophilus Tyrosyl-tRNA synthetase.
Structure (London, England : 1993) 2002;10(3):311-7.
2002: C Monnet; Florence Bettsworth; Enrico A Stura; Marie Hélène Le Du; Renée Ménez; L Derrien; Sophie Zinn-Justin; Bernard Gilquin; Geneviève Sibaï; Nicole Battail-Poirot; Michel Jolivet; André Ménez; M Arnaud; Frédéric Ducancel; Jean-Baptiste Charbonnier
Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.
Journal of molecular biology 2002;315(4):699-712.
2001: N Wolff; Bernard Gilquin; K Courchay; I Callebaut; H J Worman; Sophie Zinn-Justin
Structural analysis of emerin, an inner nuclear membrane protein mutated in X-linked Emery-Dreifuss muscular dystrophy.
FEBS letters 2001;501(2-3):171-6.
2001: C Laguri; Bernard Gilquin; Nicolas Wolff; Régine Romi-Lebrun; K Courchay; Isabelle Callebaut; Howard J Worman; Sophie Zinn-Justin
Structural characterization of the LEM motif common to three human inner nuclear membrane proteins.
Structure (London, England : 1993) 2001;9(6):503-11.
2001: Florence Bettsworth; C Monnet; Benedicte Jardin-Watelet; Nicole Battail-Poirot; Bernard Gilquin; Michel Jolivet; André Menez; M Arnaud; Frédéric Ducancel
Functional characterization of two anti-estradiol antibodies as deduced from modelling and site-directed mutagenesis experiments.
Journal of molecular recognition : JMR 2001;14(2):99-109.
2001: Philippe Savarin; Sophie Zinn-Justin; Bernard Gilquin
Variability in automated assignment of NOESY spectra and three-dimensional structure determination: a test case on three small disulfide-bonded proteins.
Journal of biomolecular NMR 2001;19(1):49-62.
2000: Nicolas Wolff; M Guenneugues; Bernard Gilquin; Eugenia Drakopoulou; Claudio Vita; André Ménez; Sophie Zinn-Justin
Characterization of the internal motions of a chimeric protein by 13C NMR highlights the important dynamic consequences of the engineering on a millisecond time scale.
European journal of biochemistry / FEBS 2000;267(22):6519-33.
2000: Bernard Gilquin; C Guilbert; david perahia
Unfolding of hen egg lysozyme by molecular dynamics simulations at 300K: insight into the role of the interdomain interface.
Proteins 2000;41(1):58-74.
2000: Sophie Michalet; F Teixeira; Bernard Gilquin; Gilles Mourier; Denis Servent; Pascal Drevet; P Binder; S Tzartos; André Ménez; Pascal Kessler
Relative spatial position of a snake neurotoxin and the reduced disulfide bond alpha (Cys192-Cys193) at the alpha gamma interface of the nicotinic acetylcholine receptor.
The Journal of biological chemistry 2000;275(33):25608-15.
1999: Philippe Savarin; Régine Romi-Lebrun; Sophie Zinn-Justin; B Lebrun; Terumi Nakajima; Bernard Gilquin; André Menez
Structural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: solution structure of the potassium channel inhibitor HsTX1.
Protein science : a publication of the Protein Society 1999;8(12):2672-85.
1999: M Guenneugues; Bernard Gilquin; Nicolas Wolff; André Ménez; Sophie Zinn-Justin
Internal motion time scales of a small, highly stable and disulfide-rich protein: a 15N, 13C NMR and molecular dynamics study.
Journal of biomolecular NMR 1999;14(1):47-66.
1999: Bernard Gilquin; Alain Lecoq; F Desné; M Guenneugues; Sophie Zinn-Justin; André Ménez
Conformational and functional variability supported by the BPTI fold: solution structure of the Ca2+ channel blocker calcicludine.
Proteins 1999;34(4):520-32.
1999: J Song; N Jamin; Bernard Gilquin; Claudio Vita; André Ménez
A gradual disruption of tight side-chain packing: 2D 1H-NMR characterization of acid-induced unfolding of CHABII.
Nature structural biology 1999;6(2):129-34.
1998: Philippe Savarin; M Guenneugues; Bernard Gilquin; Hung Lamthanh; Sylvaine Gasparini; Sophie Zinn-Justin; André Ménez
Three-dimensional structure of kappa-conotoxin PVIIA, a novel potassium channel-blocking toxin from cone snails.
Biochemistry 1998;37(16):5407-16.
1998: Claudio Vita; Jean Vizzavona; Eugenia Drakopoulou; Sophie Zinn-Justin; Bernard Gilquin; André Ménez
Novel miniproteins engineered by the transfer of active sites to small natural scaffolds.
Biopolymers 1998;47(1):93-100.
1997: M Guenneugues; Pascal Drevet; S Pinkasfeld; Bernard Gilquin; André Ménez; Sophie Zinn-Justin
Picosecond to hour time scale dynamics of a "three finger" toxin: correlation with its toxic and antigenic properties.
Biochemistry 1997;36(51):16097-108.
1997: J Song; Bernard Gilquin; N Jamin; Eugenia Drakopoulou; M Guenneugues; M Dauplais; Claudio Vita; André Ménez
NMR solution structure of a two-disulfide derivative of charybdotoxin: structural evidence for conservation of scorpion toxin alpha/beta motif and its hydrophobic side chain packing.
Biochemistry 1997;36(13):3760-6.
1997: M Dauplais; Alain Lecoq; J Song; J Cotton; N Jamin; Bernard Gilquin; Christian Roumestand; Claudio Vita; CL de Medeiros; Edward G Rowan; Alan L Harvey; André Ménez
On the convergent evolution of animal toxins. Conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures.
The Journal of biological chemistry 1997;272(7):4302-9.
1996: Sophie Zinn-Justin; M Guenneugues; Eugenia Drakopoulou; Bernard Gilquin; Claudio Vita; André Ménez
Transfer of a beta-hairpin from the functional site of snake curaremimetic toxins to the alpha/beta scaffold of scorpion toxins: three-dimensional solution structure of the chimeric protein.
Biochemistry 1996;35(26):8535-43.
1995: M Dauplais; Bernard Gilquin; Lourival D Possani; G Gurrola-Briones; Christian Roumestand; André Ménez
Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins.
Biochemistry 1995;34(51):16563-73.
1995: I Ségalas; Christian Roumestand; Sophie Zinn-Justin; Bernard Gilquin; R Ménez; André Ménez; F Toma
Solution structure of a green mamba toxin that activates muscarinic acetylcholine receptors, as studied by nuclear magnetic resonance and molecular modeling.
Biochemistry 1995;34(4):1248-60.
1994: Christian Roumestand; Bernard Gilquin; O Trémeau; E Gatineau; L Mouawad; André Ménez; F Toma
Proton NMR studies of the structural and dynamical effect of chemical modification of a single aromatic side-chain in a snake cardiotoxin. Relation to the structure of the putative binding site and the cytolytic activity of the toxin.
Journal of molecular biology 1994;243(4):719-35.
1994: Bernard Gilquin; david perahia; Vincent Dive
A free-energy simulation study of a bacterial collagenase inhibitor.
International journal of peptide and protein research 1994;43(4):384-92.
1993: Bernard Gilquin; Christian Roumestand; Sophie Zinn-Justin; André Ménez; F Toma
Refined three-dimensional solution structure of a snake cardiotoxin: analysis of the side-chain organization suggests the existence of a possible phospholipid binding site.
Biopolymers 1993;33(11):1659-75.
1992: Sophie Zinn-Justin; Christian Roumestand; Bernard Gilquin; F Bontems; André Ménez; F Toma
Three-dimensional solution structure of a curaremimetic toxin from Naja nigricollis venom: a proton NMR and molecular modeling study.
Biochemistry 1992;31(46):11335-47.
1992: F Bontems; Bernard Gilquin; Christian Roumestand; André Ménez; F Toma
Analysis of side-chain organization on a refined model of charybdotoxin: structural and functional implications.
Biochemistry 1992;31(34):7756-64.
1992: Vincent Dive; Athanasios Yiotakis; Christian Roumestand; Bernard Gilquin; J Labadie; F Toma
Peptide inhibitors of E. collagenolyticum bacterial collagenase--effect of N-methylation. Consequences on biological activity and conformational properties.
International journal of peptide and protein research 1992;39(6):506-15.
1991: F Bontems; Christian Roumestand; Bernard Gilquin; André Ménez; F Toma
Refined structure of charybdotoxin: common motifs in scorpion toxins and insect defensins.
Science (New York, N.Y.) 1991;254(5037):1521-3.
1991: F Bontems; Christian Roumestand; P Boyot; Bernard Gilquin; Y Doljansky; A Menez; F Toma
Three-dimensional structure of natural charybdotoxin in aqueous solution by 1H-NMR. Charybdotoxin possesses a structural motif found in other scorpion toxins.
European journal of biochemistry / FEBS 1991;196(1):19-28.
1990: André Ménez; E Gatineau; Christian Roumestand; Alan L Harvey; L Mouawad; Bernard Gilquin; F Toma
Do cardiotoxins possess a functional site? Structural and chemical modification studies reveal the functional site of the cardiotoxin from Naja nigricollis.
Biochimie 1990;72(8):575-88.