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Carine Giovannangeli

Research Profile

Chemicals & Drugs

Concepts & Ideas

Nucleic Acid Conformation

Physiology

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Publications

TOP 3
Fanny Marlin; Loïc Perrouault; TE Saison-Behmoaras; Philippe Simon; Patrizia Alberti; Charlotte Boix; Stéphanie Bonneau; Céline Cordier; Marc Fontecave; Aurélie Fossey; Carine Giovannangeli
Flavin conjugates for delivery of peptide nucleic acids.
Koji Nakanishi; Francesca Cavallo; Loïc Perrouault; Carine Giovannangeli; Mary Ellen Moynahan; Marco Barchi; Erika Brunet; Maria Jasin
Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication.
Jean-Paul Concorder; Carine Giovannangeli
Engineered nucleases for targeted genome modification.

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All Publications

2012: Fanny Marlin; Loïc Perrouault; TE Saison-Behmoaras; Philippe Simon; Patrizia Alberti; Charlotte Boix; Stéphanie Bonneau; Céline Cordier; Marc Fontecave; Aurélie Fossey; Carine Giovannangeli
Flavin conjugates for delivery of peptide nucleic acids.
Chembiochem : a European journal of chemical biology 2012;13(17):2593-8.
2011: Koji Nakanishi; Francesca Cavallo; Loïc Perrouault; Carine Giovannangeli; Mary Ellen Moynahan; Marco Barchi; Erika Brunet; Maria Jasin
Homology-directed Fanconi anemia pathway cross-link repair is dependent on DNA replication.
Nature structural & molecular biology 2011;18(4):500-3.
2011: Jean-Paul Concorder; Carine Giovannangeli
Engineered nucleases for targeted genome modification.
Current gene therapy 2011;11(1):1.
2010: Fanny Marlin; Philippe Simon; TE Saison-Behmoaras; Carine Giovannangeli
Delivery of oligonucleotides and analogues: the oligonucleotide conjugate-based approach.
Chembiochem : a European journal of chemical biology 2010;11(11):1493-500.
2008: Philippe Simon; Fabio Cannata; Jean-Paul Concordet; Carine Giovannangeli
Targeting DNA with triplex-forming oligonucleotides to modify gene sequence.
Biochimie 2008;90(8):1109-16.
2008: Fabio Cannata; Erika Brunet; Loïc Perrouault; Victoria Roig; SLIMANE AIT-SI-ALI; Ulysse Asseline; Jean-Paul Concordet; Carine Giovannangeli
Triplex-forming oligonucleotide-orthophenanthroline conjugates for efficient targeted genome modification.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9576-81.
2008: Philippe Simon; Fabio Cannata; Loïc Perrouault; Ludovic Halby; Jean-Paul Concordet; Alexandre Boutorine; Vladimir Ryabinin; Alexandre Sinyakov; Carine Giovannangeli
Sequence-specific DNA cleavage mediated by bipyridine polyamide conjugates.
Nucleic acids research 2008;36(11):3531-8.
2007: Alexandre S Boutorine; Ludovic Halby; Philippe Simon; Loïc Perrouault; Carine Giovannangeli; Georgy V Gursky; Anna N Surovaya; Sergei Grokhovsky; Vladimir A Ryabinin; Alexandre N Sinyakov
Sequence-specific recognition of double-stranded DNA by synthetic minor groove binder conjugates. toward the construction of artificial site-specific deoxyribonucleases.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1559-63.
2007: Fatima Boutimah-Hamoudi; Erwan Leforestier; Catherine Sénamaud-Beaufort; Peter E Nielsen; Carine Giovannangeli; Tula Ester Saison-Behmoaras
Cellular antisense activity of peptide nucleic acid (PNAs) targeted to HIV-1 polypurine tract (PPT) containing RNA.
Nucleic acids research 2007;35(12):3907-17.
2007: Zahra Hassani; Jean-Christophe François; Gladys Alfama; Ghislaine Morvan Dubois; Mathilde Paris; Carine Giovannangeli; Barbara A Demeneix
A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain.
Nucleic acids research 2007;35(9):e65.
2006: Erika Brunet; Maddalena Corgnali; Fabio Cannata; Loïc Perrouault; Carine Giovannangeli
Targeting chromosomal sites with locked nucleic acid-modified triplex-forming oligonucleotides: study of efficiency dependence on DNA nuclear environment.
Nucleic acids research 2006;34(16):4546-53.
2006: Maria Duca; Dominique Guianvarc'h; Kahina Oussedik; Ludovic Halby; Anna Garbesi; Daniel Dauzonne; Claude Monneret; Neil Osheroff; Carine Giovannangeli; Paola B Arimondo
Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides.
Nucleic acids research 2006;34(6):1900-11.
2006: Paola B Arimondo; Craig J Thomas; Kahina Oussedik; Brigitte Baldeyrou; Christine Mahieu; Ludovic Halby; Dominique Guianvarc'h; Amélie Lansiaux; Sidney Hecht; Christian Bailly; Carine Giovannangeli
Exploring the cellular activity of camptothecin-triple-helix-forming oligonucleotide conjugates.
Molecular and cellular biology 2006;26(1):324-33.
2005: Erika Brunet; Patrizia Alberti; Loïc Perrouault; Ravindra Babu; Jesper Wengel; Carine Giovannangeli
Exploring cellular activity of locked nucleic acid-modified triplex-forming oligonucleotides and defining its molecular basis.
The Journal of biological chemistry 2005;280(20):20076-85.
2005: Zahra Hassani; Gregory F Lemkine; Patrick Erbacher; Karima Palmier; Gladys Alfama; Carine Giovannangeli; Jean-Paul Behr; Barbara A Demeneix
Lipid-mediated siRNA delivery down-regulates exogenous gene expression in the mouse brain at picomolar levels.
The journal of gene medicine 2005;7(2):198-207.
2005: Erika Brunet; Maddalena Corgnali; Loïc Perrouault; Victoria Roig; Ulysse Asseline; Mads D Sørensen; B Ravindra Babu; Jesper Wengel; Carine Giovannangeli
Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: improving DNA binding properties and reaching cellular activities.
Nucleic acids research 2005;33(13):4223-34.
2005: Charlotte Andrieu-Soler; Mariana Casas; Anne-Marie Faussat; Christelle Gandolphe; Marc Doat; Denis Tempé; Carine Giovannangeli; Francine Behar-Cohen; Jean-Paul Concordet
Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAs.
Nucleic acids research 2005;33(12):3733-42.
2004: Robert Besch; Carine Giovannangeli; Klaus Degitz
Triplex-forming oligonucleotides - sequence-specific DNA ligands as tools for gene inhibition and for modulation of DNA-associated functions.
Current drug targets 2004;5(8):691-703.
2004: Darya S Novopashina; Alexandre N Sinyakov; Vladimir A Ryabinin; Alya G Venyaminova; Loïc Perrouault; Erika Brunet; Carine Giovannangeli; Alexandre S Boutorine
Binding properties of the conjugates of oligo(2'-O-methylribonucleotides) with minor groove binders targeted to double stranded DNA.
Nucleosides, nucleotides & nucleic acids 2004;23(6-7):1015-22.
2004: Robert Besch; Carine Giovannangeli; Theda Schuh; Claudia Kammerbauer; Klaus Degitz
Characterization and quantification of triple helix formation in chromosomal DNA.
Journal of molecular biology 2004;341(4):979-89.
2004: Robert Besch; Christoph Marschall; Theda Schuh; Carine Giovannangeli; Claudia Kammerbauer; Klaus Degitz
Triple helix-mediated inhibition of gene expression is increased by PUVA.
The Journal of investigative dermatology 2004;122(5):1114-20.
2004: francois guillonneau; AL Guieysse; S Nocentini; Carine Giovannangeli; Danièle Praseuth
Psoralen interstrand cross-link repair is specifically altered by an adjacent triple-stranded structure.
Nucleic acids research 2004;32(3):1143-53.
2002: Robert Besch; Carine Giovannangeli; Claudia Kammerbauer; Klaus Degitz
Specific inhibition of ICAM-1 expression mediated by gene targeting with Triplex-forming oligonucleotides.
The Journal of biological chemistry 2002;277(36):32473-9.
2001: Silvia Diviacco; Valentina Rapozzi; Luigi E Xodo; C Helene; Franco Quadrifoglio; Carine Giovannangeli
Site-directed inhibition of DNA replication by triple helix formation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(14):2660-8.
2001: M Faria; Carine Giovannangeli
Triplex-forming molecules: from concepts to applications.
The journal of gene medicine 2001;3(4):299-310.
2001: Yves Aubert; Loïc Perrouault; Claude Hélène; Carine Giovannangeli; Ulysse Asseline
Synthesis and properties of triple helix-forming oligodeoxyribonucleotides containing 7-chloro-7-deaza-2'-deoxyguanosine.
Bioorganic & medicinal chemistry 2001;9(6):1617-24.
2001: M Faria; CD Wood; MR White; Claude Hélène; Carine Giovannangeli
Transcription inhibition induced by modified triple helix-forming oligonucleotides: a quantitative assay for evaluation in cells.
Journal of molecular biology 2001;306(1):15-24.
2001: M Faria; D G Spiller; C Dubertret; J S Nelson; MR White; D Scherman; Claude Hélène; Carine Giovannangeli
Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo.
Nature biotechnology 2001;19(1):40-4.
2000: Carine Giovannangeli; Claude Hélène
Triplex technology takes off.
Nature biotechnology 2000;18(12):1245-6.
2000: Carine Giovannangeli; Claude Hélène
Triplex-forming molecules for modulation of DNA information processing.
Current opinion in molecular therapeutics 2000;2(3):288-96.
2000: M Faria; CD Wood; Loïc Perrouault; J S Nelson; A Winter; MR White; C Helene; Carine Giovannangeli
Targeted inhibition of transcription elongation in cells mediated by triplex-forming oligonucleotides.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):3862-7.
2000: FX Barre; Slimane Ait-Si-Ali; Carine Giovannangeli; R Luis; SLIMANE AIT-SI-ALI; Linda L Pritchard; C Helene; Annick Harel-Bellan
Unambiguous demonstration of triple-helix-directed gene modification.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3084-8.
2000: AL Guieysse; Danièle Praseuth; Carine Giovannangeli; Ulysse Asseline; Claude Hélène
Psoralen adducts induced by triplex-forming oligonucleotides are refractory to repair in HeLa cells.
Journal of molecular biology 2000;296(2):373-83.
1999: FX Barre; Carine Giovannangeli; Claude Hélène; Annick Harel-Bellan
Covalent crosslinks introduced via a triple helix-forming oligonucleotide coupled to psoralen are inefficiently repaired.
Nucleic acids research 1999;27(3):743-9.
1997: Carine Giovannangeli; Claude Hélène
Progress in developments of triplex-based strategies.
Antisense & nucleic acid drug development 1997;7(4):413-21.
1997: Carine Giovannangeli; Silvia Diviacco; V Labrousse; Sergei Gryaznov; Pierre Charneau; C Helene
Accessibility of nuclear DNA to triplex-forming oligonucleotides: the integrated HIV-1 provirus as a target.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(1):79-84.
1997: Claude Hélène; Carine Giovannangeli; A L Guieysse-Peugeot; Danièle Praseuth
Sequence-specific control of gene expression by antigene and clamp oligonucleotides.
Ciba Foundation symposium 1997;209():94-102; discussion 102-6.