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Jack Arbiser

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TOP 3
Jack L Arbiser
Zebrafish lead the way in control of vascular permeability.
Chunhua Yu; Hui Ying Zhang; Qiuyang Zhang; Xi Zhang; Jack L Arbiser; Edaire Cheng; Xiaofang Huo; Stuart Jon Spechler; David H Wang; Rhonda F Souza
Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells.
Jack L Arbiser; Maria Bips; Michael Y Bonner; Anne Seidler; Charles Kovach
Combination therapy of imiquimod and gentian violet for cutaneous melanoma metastases.

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All Publications

2012: Jack L Arbiser
Zebrafish lead the way in control of vascular permeability.
Blood 2012;120(11):2162-4.
2012: Chunhua Yu; Hui Ying Zhang; Qiuyang Zhang; Xi Zhang; Jack L Arbiser; Edaire Cheng; Xiaofang Huo; Stuart Jon Spechler; David H Wang; Rhonda F Souza
Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells.
American journal of physiology. Gastrointestinal and liver physiology 2012;303(5):G561-9.
2012: Jack L Arbiser; Maria Bips; Michael Y Bonner; Anne Seidler; Charles Kovach
Combination therapy of imiquimod and gentian violet for cutaneous melanoma metastases.
Journal of the American Academy of Dermatology 2012;67(2):e81-3.
2012: Michael Y Bonner; Jack L Arbiser
Targeting NADPH oxidases for the treatment of cancer and inflammation.
Cellular and molecular life sciences : CMLS 2012;69(14):2435-42.
2012: Chie Ishikawa; Jack L Arbiser; Naoki Mori
Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia.
Biochimica et biophysica acta 2012;1820(7):879-87.
2012: Jack L Arbiser
NHERF-2 silences the silencers.
Blood 2012;119(20):4582-4.
2012: Jennifer M Munson; Sydney A Rowson; Jack L Arbiser; Michael Y Bonner; Daniel J Brat; Sara A Courtneidge; Begoña Diaz; Levi Fried; Lohitash Karumbaiah; Ulla G Knaus; Ravi V Bellamkonda
Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma.
Science translational medicine 2012;4(127):127ra36.
2012: Itzamarie Chévere-Torres; Michael J Gambello; Areum Kang; Hanoch Kaphzan; Jack L Arbiser; Aditi Bhattacharya; Jordan M Maki; Emanuela Santini; Eric Klann
Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex.
Neurobiology of disease 2012;45(3):1101-10.
2012: Baskaran Govindarajan; Marsha A Moses; Emir Veledar; Laura Willoughby; Hamid Band; Michael Y Bonner; Suephy Chen; Adam S Curatolo; Martin-Garrido Abel; Jack L Arbiser
Cooperative benefit for the combination of rapamycin and imatinib in tuberous sclerosis complex neoplasia.
Vascular cell 2012;4(1):11.
2012: Arumugam Nagalingam; Neeraj Saxena; Jack L Arbiser; Michael Y Bonner; Dipali Sharma
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis.
Breast cancer research : BCR 2012;14(1):R35.
2011: Masayoshi Yamaguchi; Jack L Arbiser; Mervyn WEITZMANN
Honokiol stimulates osteoblastogenesis by suppressing NF-κB activation.
International journal of molecular medicine 2011;28(6):1049-53.
2011: Sabrina Diano; Marcelo O Dietrich; Xiao-Bing Gao; Erika Gyengesi; Jack L Arbiser; Denise D Belsham; Anton M Bennett; Jin Kwon Jeong; Kaitlin Kelly; Esther Kim; Zhong-Wu Liu; Charles V Mobbs; Hai-Bin Ruan; David A Sarruf; Michael W Schwartz; Marya Shanabrough; Shigetomo Suyama; Xiaoyong Yang; Tamas L Horvath
Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity.
Nature medicine 2011;17(9):1121-7.
2011: Jack L Arbiser
Beating the rap in angiogenesis.
Blood 2011;118(7):1719-20.
2011: Stephanie Carnesecchi; Christine Deffert; Yves Donati; Cecile Guichard; Boris Hinz; Jack L Arbiser; Botond Banfi; Constance Barazzone Argiroffo; Olivier Basset; Jean-Claude Pache; Olivier Preynat-Seauve; Karl-Heinz Krause
A key role for NOX4 in epithelial cell death during development of lung fibrosis.
Antioxidants & redox signaling 2011;15(3):607-19.
2011: Jack L Arbiser
Fumarate esters as angiogenesis inhibitors: key to action in psoriasis?
The Journal of investigative dermatology 2011;131(6):1189-91.
2011: Jack L Arbiser; David E Fisher
Fisetin: a natural fist against melanoma?
The Journal of investigative dermatology 2011;131(6):1187-9.
2011: Ricardo L Berrios; Jack L Arbiser
Novel antiangiogenic agents in dermatology.
Archives of biochemistry and biophysics 2011;508(2):222-6.
2011: Xu Zhang; Yujuan Zheng; Levi E Fried; Yatao Du; Sergio J Montano; Allie Sohn; Benjamin Lefkove; Lars Holmgren; Jack L Arbiser; Arne Holmgren; Jun Lu
Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes.
Free radical biology & medicine 2011;50(7):811-20.
2011: Cynthia Bartus; Lawrence F Brown; Michael Y Bonner; Jack L Arbiser
High level expression of angiopoietin-2 in human abscesses.
Journal of the American Academy of Dermatology 2011;64(1):200-1.
2011: Ricardo L Berrios; Jack L Arbiser
Effectiveness of gentian violet and similar products commonly used to treat pyodermas.
Dermatologic clinics 2011;29(1):69-73.
2010: Benjamin Stoff; Jamie MacKelfresh; Levi Fried; Cynthia Cohen; Jack L Arbiser
A nonsteroidal alternative to impetiginized eczema in the emergency room.
Journal of the American Academy of Dermatology 2010;63(3):537-9.
2010: Wei-Ting Liao; Hsin-Su Yu; Jack L Arbiser; Chein-Hui Hong; Baskaran Govindarajan; Chih-Yin Chai; Wan-Ju Shan; Yu-Fen Lin; Gwo-Shing Chen; Abel Lee
Enhanced MCP-1 release by keloid CD14+ cells augments fibroblast proliferation: role of MCP-1 and Akt pathway in keloids.
Experimental dermatology 2010;19(8):e142-50.
2010: Jack L Arbiser
EC-specific chemotaxis receptor: a double-edged sword.
Blood 2010;115(22):4328-9.
2010: Sareeta R S Parker; Carmen Traywick; Jack L Arbiser
Ulcerative granulomatous mycosis fungoides.
Skinmed 2010;8(3):188-90.
2010: Rebecca J Leeman-Neill; Quan Cai; Sonali C Joyce; Sufi Thomas; Neil E Bhola; Daniel B Neill; Jack L Arbiser; Jennifer Rubin Grandis
Honokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(9):2571-9.
2010: Sundararaman Swaminathan; Jack L Arbiser; Kim M Hiatt; Whitney High; Sameh Abul-Ezz; Thomas D Horn; Sudhir V Shah
Rapid improvement of nephrogenic systemic fibrosis with rapamycin therapy: possible role of phospho-70-ribosomal-S6 kinase.
Journal of the American Academy of Dermatology 2010;62(2):343-5.
2010: Jack L Arbiser
Translating cyclooxygenase signaling in patch heterozygote mice into a randomized clinical trial in basal cell carcinoma.
Cancer prevention research (Philadelphia, Pa.) 2010;3(1):4-7.
2009: Jack L Arbiser; M Y Bonner; R L Berrios
Hemangiomas, angiosarcomas, and vascular malformations represent the signaling abnormalities of pathogenic angiogenesis.
Current molecular medicine 2009;9(8):929-34.
2009: Ramon Alvin Chua; Jack L Arbiser
The role of angiogenesis in the pathogenesis of psoriasis.
Autoimmunity 2009;42(7):574-9.
2009: Ramon Alvin Chua; Jamie MacKelfresh; Cynthia Cohen; Vijay Varma; Levi Fried; Jack L Arbiser
Disseminated pyoderma gangrenosum: role for vascular endothelial growth factor and hypoxia inducible factor-2.
Journal of the American Academy of Dermatology 2009;61(4):730-2.
2009: Bobby Bhatia; Paul A Northcott; Dolares Hambardzumyan; Baskaran Govindarajan; Daniel J Brat; Jack L Arbiser; Eric C Holland; Michael D Taylor; Anna Marie Kenney
Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization.
Cancer research 2009;69(18):7224-34.
2009: Sulochana S Bhandarkar; Marisa Jaconi; Levi E Fried; Michael Y Bonner; Benjamin Lefkove; Baskaran Govindarajan; Betsy N Perry; Ravi Parhar; Jamie MacKelfresh; Allie Sohn; Michael Stouffs; Ulla G Knaus; George D Yancopoulos; Yvonne Reiss; Andrew V Benest; Hellmut G Augustin; Jack L Arbiser
Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.
The Journal of clinical investigation 2009;119(8):2359-65.
2009: Jack L Arbiser
Gentian violet is safe.
Journal of the American Academy of Dermatology 2009;61(2):359.
2009: Andrew Courtwright; Sharareh Siamakpour-Reihani; Jack L Arbiser; Natalie Banet; Eleanor Hilliard; Levi Fried; Chad A Livasy; David Ketelsen; Desh Bandhu Nepal; Charles M Perou; Winston Patterson; Nancy Demore
Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathway.
Cancer research 2009;69(11):4621-8.
2009: Jack L Arbiser; Michael Y Bonner
Melanomas reveal their nakedness: uncovered by interferon alfa.
Archives of dermatology 2009;145(5):587-8.
2009: Ramon Chua; Shannon Setzer; Baskaran Govindarajan; Debbie Sexton; Cynthia Cohen; Jack L Arbiser
Maspin expression, angiogenesis, prognostic parameters, and outcome in malignant melanoma.
Journal of the American Academy of Dermatology 2009;60(5):758-66.
2009: Levi E Fried; Jack L Arbiser
Honokiol, a multifunctional antiangiogenic and antitumor agent.
Antioxidants & redox signaling 2009;11(5):1139-48.
2009: Jack L Arbiser
Unexpected autocrine role of vascular endothelial growth factor in squamous cell carcinoma.
The Journal of investigative dermatology 2009;129(3):538-40.
2009: Moshe Lapidoth; Dan Ben-Amitai; Sulochana Bhandarkar; Levi Fried; Jack L Arbiser
Efficacy of topical application of eosin for ulcerated hemangiomas.
Journal of the American Academy of Dermatology 2009;60(2):350-1.
2009: Jack L Arbiser; Levi Fried
The hunting of the Snrk.
Blood 2009;113(5):983-4.
2008: Caroline Le Poole; Cecele J Denman; Jack L Arbiser
Immunosuppression may be present within condyloma acuminata.
Journal of the American Academy of Dermatology 2008;59(6):967-74.
2008: Junguk Park; Gunnar F Kaufmann; J Phillip Bowen; Jack L Arbiser; Kim D Janda
Solenopsin A, a venom alkaloid from the fire ant Solenopsis invicta, inhibits quorum-sensing signaling in Pseudomonas aeruginosa.
The Journal of infectious diseases 2008;198(8):1198-201.
2008: Sulochana S Bhandarkar; Jacqueline F Bromberg; Carol Carrillo; Ponniah Selvakumar; Rajendra K Sharma; Betsy N Perry; Baskaran Govindarajan; Levi Fried; Allie Sohn; Kalpana Reddy; Jack L Arbiser
Tris (dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5743-8.
2008: Sergey Dikalov; Tanya Losik; Jack L Arbiser
Honokiol is a potent scavenger of superoxide and peroxyl radicals.
Biochemical pharmacology 2008;76(5):589-96.
2008: Kalpana K Reddy; Benjamin Lefkove; Lan Bo Chen; Baskaran Govindarajan; Arkaitz Carracedo; Guillermo Velasco; Carol O Carrillo; Sulochana S Bhandarkar; Michael J Owens; Fatima Mechta-Grigoriou; Jack L Arbiser
The antidepressant sertraline downregulates Akt and has activity against melanoma cells.
Pigment cell & melanoma research 2008;21(4):451-6.
2008: Benoit Boivin; Sheng Zhang; Jack L Arbiser; Zhong-Yin Zhang; Nicholas K Tonks
A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(29):9959-64.
2008: Shruti M Raja; Shuzhen Chen; Ping Yue; Timothy M Acker; Benjamin Lefkove; Jack L Arbiser; Fadlo R Khuri; Shi-Yong Sun
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.
Molecular cancer therapeutics 2008;7(7):2212-23.
2008: Avalon Garcia; Yang Zheng; Chen Zhao; Alfredo Toschi; Judy Fan; Natalie Shraibman; H Alex Brown; Dafna Bar-Sagi; David A Foster; Jack L Arbiser
Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(13):4267-74.
2008: Linda P Fried; Jack L Arbiser
The reactive oxygen-driven tumor: relevance to melanoma.
Pigment cell & melanoma research 2008;21(2):117-22.
2008: Sulochana S Bhandarkar; Jamie MacKelfresh; Levi Fried; Jack L Arbiser
Targeted therapy of oral hairy leukoplakia with gentian violet.
Journal of the American Academy of Dermatology 2008;58(4):711-2.
2008: Nina Funa; Kalpana Reddy; Sulochana S Bhandarkar; Elena Kurenova; Lily Yang; William G Cance; Michael Welsh; Jack L Arbiser
Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo.
The Journal of investigative dermatology 2008;128(3):710-6.
2008: Levi E Fried; Jack L Arbiser
Application of angiogenesis to clinical dermatology.
Advances in dermatology 2008;24():89-103.
2008: Levi Fried; Robert S Kirsner; Sulochana Bhandarkar; Jack L Arbiser
Efficacy of rapamycin in scleroderma: a case study.
Lymphatic research and biology 2008;6(3-4):217-9.
2007: Sulochana S Bhandarkar; Cynthia Cohen; Maria Kuruvila; Thomas H Rea; Jamie MacKelfresh; Delphine J Lee; Robert L Modlin; Jack L Arbiser
Angiogenesis in cutaneous lesions of leprosy: implications for treatment.
Archives of dermatology 2007;143(12):1527-9.
2007: Jack L Arbiser
Why targeted therapy hasn't worked in advanced cancer.
The Journal of clinical investigation 2007;117(10):2762-5.
2007: Franck Amblard; Baskaran Govindarajan; Benjamin Lefkove; Kimberly L Rapp; Mervi Detorio; Jack L Arbiser; Ray F Schinazi
Synthesis, cytotoxicity, and antiviral activities of new neolignans related to honokiol and magnolol.
Bioorganic & medicinal chemistry letters 2007;17(16):4428-31.
2007: Benjamin Lefkove; Baskaran Govindarajan; Jack L Arbiser
Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors.
Expert review of anti-infective therapy 2007;5(4):573-9.
2007: Melissa Munroe; Jack L Arbiser; Gail A Bishop
Honokiol, a natural plant product, inhibits inflammatory signals and alleviates inflammatory arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):753-63.
2007: Ido Wolf; James O'Kelly; Naoki Wakimoto; Anh Nguyen; Franck Amblard; Beth Y Karlan; Jack L Arbiser; H Phillip Koeffler
Honokiol, a natural biphenyl, inhibits in vitro and in vivo growth of breast cancer through induction of apoptosis and cell cycle arrest.
International journal of oncology 2007;30(6):1529-37.
2007: Betsy Perry; Jacqueline Banyard; Elizabeth R McLaughlin; Randy Watnick; Allie Sohn; David N Brindley; Toshiyuki Obata; Lewis C Cantley; Cynthia Cohen; Jack L Arbiser
AKT1 overexpression in endothelial cells leads to the development of cutaneous vascular malformations in vivo.
Archives of dermatology 2007;143(4):504-6.
2007: Katsumi Shigemura; Jack L Arbiser; Shi-Yong Sun; Majd zayzafoon; Peter A S Johnstone; Masato Fujisawa; Akinobu Gotoh; Babette Weksler; Haiyen E Zhau; Leland W K Chung
Honokiol, a natural plant product, inhibits the bone metastatic growth of human prostate cancer cells.
Cancer 2007;109(7):1279-89.
2007: So Dug Lim; William Stallcup; Benjamin Lefkove; Baskaran Govindarajan; Kit-Sing Au; Hope Northrup; Deborah Lang; David E Fisher; Avani Patel; Mahul B Amin; Jack L Arbiser
Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem cells?
Molecular medicine (Cambridge, Mass.) 2007;13(3-4):160-5.
2007: Baskaran Govindarajan; James E Sligh; Bethaney J Vincent; Meiling Li; Jeffrey A Canter; Brian J Nickoloff; Richard J Rodenburg; Jan A M Smeitink; Larry Oberley; Yuping Zhang; Joyce M Slingerland; Rebecca S Arnold; David J. Lambeth; Cynthia Cohen; Lula Hilenski; Kathy K Griendling; Marta Martínez-Diez; José M Cuezva; Jack L Arbiser
Overexpression of Akt converts radial growth melanoma to vertical growth melanoma.
The Journal of clinical investigation 2007;117(3):719-29.
2007: Jack L Arbiser; Tweeny Kau; Martha Konar; Krishna Narra; Ramani Ramchandran; Scott A Summers; chris vlahos; Keqiang Ye; Betsy N Perry; William F Matter; Anthony Fischl; James Cook; Pamela A Silver; Jenny Bain; Philip Cohen; David Whitmire; Scott Furness; Baskaran Govindarajan; J Phillip Bowen
Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis.
Blood 2007;109(2):560-5.
2007: Farheen Shirazi; Cynthia Cohen; Levi Fried; Jack L Arbiser
Mammalian target of rapamycin (mTOR) is activated in cutaneous vascular malformations in vivo.
Lymphatic research and biology 2007;5(4):233-6.
2007: Sulochana S Bhandarkar; Jack L Arbiser
Curcumin as an inhibitor of angiogenesis.
Advances in experimental medicine and biology 2007;595():185-95.
2006: Jack L Arbiser; Karen P Mann; Elizabeth M Losken; Cynthia Cohen; Kalpana Reddy; Kenneth Kokko; Brian Pollack; Chung-Yang Fan; Fiona M O'Reilly
Presence of p16 hypermethylation and Epstein-Barr virus infection in transplant-associated hematolymphoid neoplasm of the skin.
Journal of the American Academy of Dermatology 2006;55(5):794-8.
2006: Betsy N Perry; Jack L Arbiser
The duality of angiogenesis: implications for therapy of human disease.
The Journal of investigative dermatology 2006;126(10):2160-6.
2006: Betsy N Perry; Baskaran Govindarajan; Sulochana S Bhandarkar; Ulla G Knaus; Monika Valo; Celina Sturk; Carol O Carrillo; Allie Sohn; Francesca Cerimele; Daniel J Dumont; Albert Losken; Joseph Williams; Lawrence F Brown; Xiaolian Tan; Ella Ioffe; George D Yancopoulos; Jack L Arbiser
Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice.
The Journal of investigative dermatology 2006;126(10):2316-22.
2006: Kwang Seok Ahn; Gautam Sethi; Shishir Shishodia; Bokyung Sung; Jack L Arbiser; Bharat B Aggarwal
Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway.
Molecular cancer research : MCR 2006;4(9):621-33.
2006: Betsy N Perry; Cynthia Cohen; Baskaran Govindarajan; George Cotsonis; Jack L Arbiser
Wilms tumor 1 expression present in most melanomas but nearly absent in nevi.
Archives of dermatology 2006;142(8):1031-4.
2006: Franck Amblard; David Delinsky; Jack L Arbiser; Ray F Schinazi
Facile purification of honokiol and its antiviral and cytotoxic properties.
Journal of medicinal chemistry 2006;49(11):3426-7.
2006: Jack L Arbiser; Baskaran Govindarajan; Traci Battle; Rebecca Lynch; David A Frank; Masuko Fukai; Betsy N Perry; David F Stern; George Bowden; Anquan Liu; Eva Klein; Pawel J Kolodziejski; N Tony Eissa; Chowdhury Faiz Hossain; Dale G Nagle
Carbazole is a naturally occurring inhibitor of angiogenesis and inflammation isolated from antipsoriatic coal tar.
The Journal of investigative dermatology 2006;126(6):1396-402.
2005: Jamie MacKelfresh; Seaver Soon; Jack L Arbiser
Combination therapy of doxycycline and topical tacrolimus for venous ulcers.
Archives of dermatology 2005;141(11):1476-7.
2005: Leslie P Lawley; Francesca Cerimele; Sharon W Weiss; Paula North; Cynthia Cohen; Harry P W Kozakewich; John B Mulliken; Jack L Arbiser
Expression of Wilms tumor 1 gene distinguishes vascular malformations from proliferative endothelial lesions.
Archives of dermatology 2005;141(10):1297-300.
2005: Stephen Hunter; Sharon Weiss; Chin-Yih Ou; David L Jaye; Andrew Young; Josiah N Wilcox; Jack L Arbiser; David Monson; John R Goldblum; J D L Nolen; Vijay Varma
Apolipoprotein D is down-regulated during malignant transformation of neurofibromas.
Human pathology 2005;36(9):987-93.
2005: Jack L Arbiser; Xing-Cong Li; Chowdhury Faiz Hossain; Dale G Nagle; David M Smith; Paul Miller; Baskaran Govindarajan; Joshua B DiCarlo; Kristin R Landis-Piwowar; Qingping Dou
Naturally occurring proteasome inhibitors from mate tea (Ilex paraguayensis) serve as models for topical proteasome inhibitors.
The Journal of investigative dermatology 2005;125(2):207-12.
2005: Thomas Philip Robinson; Richard B Hubbard; Tedman Ehlers; Jack L Arbiser; David Goldsmith; J Phillip Bowen
Synthesis and biological evaluation of aromatic enones related to curcumin.
Bioorganic & medicinal chemistry 2005;13(12):4007-13.
2005: Jack L Arbiser
Implications of Epstein-Barr Virus (EBV)-induced carcinogenesis on cutaneous inflammation and carcinogenesis: evidence of recurring patterns of angiogenesis and signal transduction.
The Journal of investigative dermatology 2005;124(5):xi-xii.
2005: Baskaran Govindarajan; Asha Shah; Cynthia Cohen; Rebecca S Arnold; Jeffrey Schechner; Jun Chung; Arthur M Mercurio; Rhoda M Alani; Byungwoo Ryu; Chun-Yang Fan; José M Cuezva; Marta Martinez; Jack L Arbiser
Malignant transformation of human cells by constitutive expression of platelet-derived growth factor-BB.
The Journal of biological chemistry 2005;280(14):13936-43.
2005: Baskaran Govindarajan; Daniel J Brat; Marie Csete; William D Martin; Emma Murad; Karin Litani; Cynthia Cohen; Francesca Cerimele; Matthew Nunnelley; Benjamin Lefkove; Toshiyuki Yamamoto; Chunsik Lee; Jack L Arbiser
Transgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain.
The Journal of biological chemistry 2005;280(7):5870-4.
2005: Anquan Liu; Jack L Arbiser; Arne Holmgren; George Klein; Eva Klein
PSK and Trx80 inhibit B-cell growth in EBV-infected cord blood mononuclear cells through T cells activated by the monocyte products IL-15 and IL-12.
Blood 2005;105(4):1606-13.
2005: Nada C Macaron; Cynthia Cohen; Suephy C Chen; Jack L Arbiser
gli-1 Oncogene is highly expressed in granulomatous skin disorders, including sarcoidosis, granuloma annulare, and necrobiosis lipoidica diabeticorum.
Archives of dermatology 2005;141(2):259-62.
2005: Uma Nadiminti; Jack L Arbiser
Rapamycin (sirolimus) as a steroid-sparing agent in dermatomyositis.
Journal of the American Academy of Dermatology 2005;52(2 Suppl 1):17-9.
2005: Francesca Cerimele; Traci Battle; Rebecca Lynch; David A Frank; Emma Murad; Cynthia Cohen; Nada C Macaron; John Sixbey; Kenneth Smith; Randolph S Watnick; Aristidis Eliopoulos; Bahig M Shehata; Jack L Arbiser
Reactive oxygen signaling and MAPK activation distinguish Epstein-Barr Virus (EBV)-positive versus EBV-negative Burkitt's lymphoma.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(1):175-9.
2005: M S Furness; Thomas Philip Robinson; Tedman Ehlers; Richard B Hubbard; Jack L Arbiser; David Goldsmith; J Phillip Bowen
Antiangiogenic agents: studies on fumagillin and curcumin analogs.
Current pharmaceutical design 2005;11(3):357-73.
2004: Xiaojun Lu; Jack L Arbiser; James West; Marloes Hoedt-Miller; Alison Sheridan; Baskaran Govindarajan; Julie Harral; David M Rodman; Brian W Fouty
Tumor necrosis factor-related apoptosis-inducing ligand can induce apoptosis in subsets of premalignant cells.
The American journal of pathology 2004;165(5):1613-20.
2004: Jack L Arbiser; Chun-Yang Fan; Xiaobo Su; Beth O Van Emburgh; Francesca Cerimele; Mark Steven Miller; Jeff D Harvell; M Peter Marinkovich
Involvement of p53 and p16 tumor suppressor genes in recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma.
The Journal of investigative dermatology 2004;123(4):788-90.
2004: Amy Kim Gira; Lawrence F Brown; Carl V Washington; Cynthia Cohen; Jack L Arbiser
Keloids demonstrate high-level epidermal expression of vascular endothelial growth factor.
Journal of the American Academy of Dermatology 2004;50(6):850-3.
2004: Jack L Arbiser
Molecular regulation of angiogenesis and tumorigenesis by signal transduction pathways: evidence of predictable and reproducible patterns of synergy in diverse neoplasms.
Seminars in cancer biology 2004;14(2):81-91.
2004: Tetyana Levchenko; Anders Bratt; Jack L Arbiser; Lars Holmgren
Angiomotin expression promotes hemangioendothelioma invasion.
Oncogene 2004;23(7):1469-73.
2003: Girish Munavalli; Amy K Reisenauer; Marsha A Moses; Susan Kilroy; Jack L Arbiser
Weight loss-induced calciphylaxis: potential role of matrix metalloproteinases.
The Journal of dermatology 2003;30(12):915-9.
2003: Emma Rennel; Michael J Cross; Peter Klint; Xianhe Bai; Jack L Arbiser; Pär Gerwins
Regulation of endothelial cell differentiation and transformation by H-Ras.
Experimental cell research 2003;291(1):189-200.
2003: Jack L Arbiser
Activation of B-raf in non-malignant nevi predicts a novel tumor suppressor gene in melanoma (MAP kinase phosphatase).
The Journal of investigative dermatology 2003;121(5):xiv.
2003: Francesca Cerimele; Lawrence F Brown; Francisco Bravo; Garret M Ihler; Philomene Kouadio; Jack L Arbiser
Infectious angiogenesis: Bartonella bacilliformis infection results in endothelial production of angiopoetin-2 and epidermal production of vascular endothelial growth factor.
The American journal of pathology 2003;163(4):1321-7.
2003: Xianhe Bai; Francesca Cerimele; Masuko Fukai; Muhammad Waqas; Paul M Campbell; Baskaran Govindarajan; Channing J Der; Traci Battle; David A Frank; Keqiang Ye; Emma Murad; Wolfgang Dubiel; Gerald A Soff; Jack L Arbiser
Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo.
The Journal of biological chemistry 2003;278(37):35501-7.
2003: Jack L Arbiser
Role of manganese superoxide dismutase in cancer.
Nature medicine 2003;9(9):1103; author reply 1103.
2003: Jack L Arbiser
Reversing the angiogenic switch with photodynamic therapy.
The Journal of investigative dermatology 2003;121(3):xi-xii.
2003: Baskaran Govindarajan; Melissa C Mizesko; Mark Steven Miller; Hiroaki Onda; Matthew Nunnelley; Katherine Casper; Daniel J Brat; Cynthia Cohen; Jack L Arbiser; Matthew Nunnelly
Tuberous sclerosis-associated neoplasms express activated p42/44 mitogen-activated protein (MAP) kinase, and inhibition of MAP kinase signaling results in decreased in vivo tumor growth.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(9):3469-75.
2003: Nada C Macaron; Cynthia Cohen; Suephy C Chen; Jack L Arbiser
Cutaneous lesions of secondary syphilis are highly angiogenic.
Journal of the American Academy of Dermatology 2003;48(6):878-81.
2003: Jack L Arbiser; Darlene Johnson; Cynthia Cohen; Lawrence F Brown
High-level expression of vascular endothelial growth factor and its receptors in an aphthous ulcer.
Journal of cutaneous medicine and surgery 2003;7(3):225-8.
2003: Baskaran Govindarajan; Xianhe Bai; Cynthia Cohen; Hua Zhong; Susan Kilroy; Gwendolyn Louis; Marsha A Moses; Jack L Arbiser
Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling.
The Journal of biological chemistry 2003;278(11):9790-5.
2003: Thomas Philip Robinson; Tedman Ehlers; Richard B Hubbard IV; Xianhe Bai; Jack L Arbiser; David Goldsmith; J Phillip Bowen
Design, synthesis, and biological evaluation of angiogenesis inhibitors: aromatic enone and dienone analogues of curcumin.
Bioorganic & medicinal chemistry letters 2003;13(1):115-7.
2003: Katarina G Chiller; Ilona J Frieden; Jack L Arbiser
Molecular pathogenesis of vascular anomalies: classification into three categories based upon clinical and biochemical characteristics.
Lymphatic research and biology 2003;1(4):267-81.
2002: Cynthia Cohen; Angel Zavala-Pompa; Judy H Sequeira; Mamoru Shoji; Deborah G Sexton; George Cotsonis; Francesca Cerimele; Baskaran Govindarajan; Nada C Macaron; Jack L Arbiser
Mitogen-actived protein kinase activation is an early event in melanoma progression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3728-33.
2002: Jack L Arbiser; Adam W Bingaman; Megan M Durham; Shannon Cowan; Cynthia Cohen; Elham Zarnegar; Vijay Varma; Christian P Larsen
SVR angiosarcomas can be rejected by CD4 costimulation dependent and CD8 costimulation independent pathways.
Molecular medicine (Cambridge, Mass.) 2002;8(9):551-8.
2002: Jack L Arbiser; Baskaran Govindarajan; Xianhe Bai; Hiroaki Onda; Andrius Kazlauskas; So Dug Lim; Mahul B Amin; Lena Claesson-Welsh
Functional tyrosine kinase inhibitor profiling: a generally applicable method points to a novel role of platelet-derived growth factor receptor-beta in tuberous sclerosis.
The American journal of pathology 2002;161(3):781-6.
2002: Tong Tang; Jack L Arbiser; Stephen J Brandt
Phosphorylation by mitogen-activated protein kinase mediates the hypoxia-induced turnover of the TAL1/SCL transcription factor in endothelial cells.
The Journal of biological chemistry 2002;277(21):18365-72.
2002: Jack L Arbiser; Daniel J Brat; Steve Hunter; Jeanine D'Armiento; Elizabeth Petri Henske; Zoya K Arbiser; Xianhe Bai; Gerald Goldberg; Cynthia Cohen; Sharon W Weiss
Tuberous sclerosis-associated lesions of the kidney, brain, and skin are angiogenic neoplasms.
Journal of the American Academy of Dermatology 2002;46(3):376-80.
2002: Jack L Arbiser; John Petros; Robert Klafter; Baskaran Govindajaran; Elizabeth R McLaughlin; Lawrence F Brown; Cynthia Cohen; Marsha A Moses; Susan Kilroy; Rebecca S Arnold; David J. Lambeth
Reactive oxygen generated by Nox1 triggers the angiogenic switch.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):715-20.
2002: Baskaran Govindarajan; Robert Klafter; Mark Steven Miller; Claire Mansur; Melissa C Mizesko; Xianhe Bai; Kenneth LaMontagne; Jack L Arbiser
Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase.
Molecular medicine (Cambridge, Mass.) 2002;8(1):1-8.
2001: Zoya K Arbiser; Jack L Arbiser; Cynthia Cohen; Anthony A Gal
Neuroendocrine lung tumors: grade correlates with proliferation but not angiogenesis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001;14(12):1195-9.
2001: A Kim; Joshua B DiCarlo; Cynthia Cohen; Calvin O McCall; D Johnson; Barbara McAlpine; Anthony Quinn; E R McLaughlin; Jack L Arbiser
Are keloids really "gli-loids"?: High-level expression of gli-1 oncogene in keloids.
Journal of the American Academy of Dermatology 2001;45(5):707-11.
2001: E R McLaughlin; R Morris; Sharon W Weiss; Jack L Arbiser
Diffuse dermal angiomatosis of the breast: response to isotretinoin.
Journal of the American Academy of Dermatology 2001;45(3):462-5.
2001: Fiona M O'Reilly; Daniel J Brat; Barbara McAlpine; Hans E Grossniklaus; Andrew L Folpe; Jack L Arbiser
Microphthalmia transcription factor immunohistochemistry: a useful diagnostic marker in the diagnosis and detection of cutaneous melanoma, sentinel lymph node metastases, and extracutaneous melanocytic neoplasms.
Journal of the American Academy of Dermatology 2001;45(3):414-9.
2001: Jack L Arbiser; Raymond S Yeung; Sharon W Weiss; Zoya K Arbiser; Mahul B Amin; Cynthia Cohen; D Frank; Sudipta Mahajan; G S Herron; J Yang; Hiroaki Onda; H B Zhang; Xianhe Bai; E Uhlmann; A Loehr; Hope Northrup; P Au; I Davis; David E Fisher; David H Gutmann
The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms.
The American journal of pathology 2001;159(2):483-91.
2001: Jack L Arbiser; Sharon W Weiss; Zoya K Arbiser; Fernando Bravo; B Govindajaran; H Caceres-Rios; George Cotsonis; S Recavarren; Robert Swerlick; Cynthia Cohen
Differential expression of active mitogen-activated protein kinase in cutaneous endothelial neoplasms: implications for biologic behavior and response to therapy.
Journal of the American Academy of Dermatology 2001;44(2):193-7.
2000: Robert Klafter; Jack L Arbiser
Regulation of angiogenesis and tumorigenesis by signal transduction cascades: lessons from benign and malignant endothelial tumors.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2000;5(1):79-82.
2000: Kenneth LaMontagne; Marsha A Moses; DG Wiederschain; Sudipta Mahajan; J Holden; H Ghazizadeh; David A Frank; Jack L Arbiser
Inhibition of MAP kinase kinase causes morphological reversion and dissociation between soft agar growth and in vivo tumorigenesis in angiosarcoma cells.
The American journal of pathology 2000;157(6):1937-45.
2000: E R McLaughlin; Lawrence F Brown; Sharon W Weiss; J B Mulliken; A Perez-Atayde; Jack L Arbiser
VEGF and its receptors are expressed in a pediatric angiosarcoma in a patient with Aicardi's syndrome.
The Journal of investigative dermatology 2000;114(6):1209-10.
2000: Jack L Arbiser; H R Byers; Cynthia Cohen; J Arbeit
Altered basic fibroblast growth factor expression in common epidermal neoplasms: examination with in situ hybridization and immunohistochemistry.
Journal of the American Academy of Dermatology 2000;42(6):973-7.
2000: Jack L Arbiser; H Larsson; Lena Claesson-Welsh; Xianhe Bai; Kenneth LaMontagne; Sharon W Weiss; S Soker; Evelyn Flynn; Lawrence F Brown
Overexpression of VEGF 121 in immortalized endothelial cells causes conversion to slowly growing angiosarcoma and high level expression of the VEGF receptors VEGFR-1 and VEGFR-2 in vivo.
The American journal of pathology 2000;156(4):1469-76.
1999: W Wen; Marsha A Moses; DG Wiederschain; Jack L Arbiser; Judah Folkman
The generation of endostatin is mediated by elastase.
Cancer research 1999;59(24):6052-6.
1999: Jack L Arbiser; Katia P Karalis; A Viswanathan; C Koike; Bela Anand-Apte; E Flynn; Bruce R Zetter; J A Majzoub
Corticotropin-releasing hormone stimulates angiogenesis and epithelial tumor growth in the skin.
The Journal of investigative dermatology 1999;113(5):838-42.
1999: Jack L Arbiser; G Raab; Richard M Rohan; S Paul; K Hirschi; Evelyn Flynn; E Roydon Price; David E Fisher; Cynthia Cohen; Michael Klagsbrun
Isolation of mouse stromal cells associated with a human tumor using differential diphtheria toxin sensitivity.
The American journal of pathology 1999;155(3):723-9.
1999: Jack L Arbiser; D Panigrathy; Nancy Demore; Maria A Rupnick; Evelyn Flynn; Taturo Udagawa; Robert J D'Amato
The antiangiogenic agents TNP-470 and 2-methoxyestradiol inhibit the growth of angiosarcoma in mice.
Journal of the American Academy of Dermatology 1999;40(6 Pt 1):925-9.
1998: Jack L Arbiser; S K Kraeft; R van Leeuwen; Selwyn J Hurwitz; Martin K Selig; G R Dickersin; A Flint; HR Byers; L B Chen
Clioquinol-zinc chelate: a candidate causative agent of subacute myelo-optic neuropathy.
Molecular medicine (Cambridge, Mass.) 1998;4(10):665-70.
1998: L Holmgren; G Jackson; Jack L Arbiser
p53 induces angiogenesis-restricted dormancy in a mouse fibrosarcoma.
Oncogene 1998;17(7):819-24.
1998: Jack L Arbiser; Nancy Demore; Richard M Rohan; R van Leeuwen; M T Huang; C Fisher; Evelyn Flynn; HR Byers
Curcumin is an in vivo inhibitor of angiogenesis.
Molecular medicine (Cambridge, Mass.) 1998;4(6):376-83.
1998: Jack L Arbiser; Evelyn Flynn; Raymond L Barnhill
Analysis of vascularity of human neurofibromas.
Journal of the American Academy of Dermatology 1998;38(6 Pt 1):950-4.
1998: Jack L Arbiser; Jo-David Fine; Dédée F Murrell; A Paller; Stephanie A Connors; K Keough; E Marsh; J Folkman
Basic fibroblast growth factor: a missing link between collagen VII, increased collagenase, and squamous cell carcinoma in recessive dystrophic epidermolysis bullosa.
Molecular medicine (Cambridge, Mass.) 1998;4(3):191-5.
1997: Jack L Arbiser
American Academy of Dermatology 1997 Awards for Young Investigators in Dermatology. Signal transduction and regulation of angiogenesis.
Journal of the American Academy of Dermatology 1997;37(5 Pt 1):772-7.
1997: Jack L Arbiser; Rhoda M Alani; Evelyn Flynn; V Wooten; HR Byers
Effects of thallium ion on cellular components of the skin.
The Journal of dermatology 1997;24(3):147-55.
1997: Jack L Arbiser; Marsha A Moses; CA Fernandez; N Ghiso; Y Cao; Nancy Demore; D Frank; Michael Brownlee; Evelyn Flynn; S Parangi; HR Byers; Judah Folkman
Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(3):861-6.
1996: W D Tope; Jack L Arbiser; Lyn M Duncan
Black tattoo reaction: the peacock's tale.
Journal of the American Academy of Dermatology 1996;35(3 Pt 1):477-9.
1996: Jack L Arbiser
Angiogenesis and the skin: a primer.
Journal of the American Academy of Dermatology 1996;34(3):486-97.
1995: Jack L Arbiser
Genetic immunodeficiencies: cutaneous manifestations and recent progress.
Journal of the American Academy of Dermatology 1995;33(1):82-9.
1995: Jack L Arbiser; J S Dzieczkowski; J V Harmon; Lyn M Duncan
Leukocytoclastic vasculitis following staphylococcal protein A column immunoadsorption therapy. Two cases and a review of the literature.
Archives of dermatology 1995;131(6):707-9.
1995: Jack L Arbiser; S L Moschella
Clofazimine: a review of its medical uses and mechanisms of action.
Journal of the American Academy of Dermatology 1995;32(2 Pt 1):241-7.
1995: Jack L Arbiser; J Katz
Hemophilus influenzae bacteremia in elderly men with Kaposi's sarcoma: two case reports and a review of the literature.
Cutis; cutaneous medicine for the practitioner 1995;55(2):101-3.
1994: R L van Leeuwen; S K Dekker; Jack L Arbiser; Bert-Jan Vermeer; Jan A Bruijn; H R Byers
Phorbol ester induced rapid attachment and spreading of melanoma cells and the role of extracellular matrix proteins.
International journal of cancer. Journal international du cancer 1994;57(6):894-900.
1994: Jack L Arbiser; K Grossman; E Kaye; K A Arndt
Use of short-course class 1 topical glucocorticoid under occlusion for the rapid control of erythrodermic psoriasis.
Archives of dermatology 1994;130(6):704-6.
1994: Jack L Arbiser; C Martinez; Z K Arbiser; G K Adler; L B Rosen; Joseph A Majzoub
Regulation of the ectopically expressed human glycoprotein alpha-subunit gene in the human hepatoma cell line NPLC.
Endocrinology 1994;134(2):582-7.
1993: Jack L Arbiser; Z K Arbiser; Joseph A Majzoub
Effects of hydroxyurea and cyclic adenosine monophosphate/protein kinase A inhibitors on the expression of the human chorionic gonadotropin alpha subunit and c-myc genes in choriocarcinoma.
Journal of endocrinological investigation 1993;16(11):849-56.
1993: Jack L Arbiser; Z K Arbiser; Joseph A Majzoub
Differential regulation of choriocarcinoma gene expression by DNA synthesis inhibitors.
Endocrine journal 1993;40(2):263-8.
1991: Jack L Arbiser; Z K Arbiser; Joseph A Majzoub
Regulation of gene expression in choriocarcinoma by methotrexate and hydroxyurea.
Endocrinology 1991;128(2):972-8.
1989: B G Robinson; Jack L Arbiser; Rodica L Emanuel; Joseph A Majzoub
Species-specific placental corticotropin releasing hormone messenger RNA and peptide expression.
Molecular and cellular endocrinology 1989;62(2):337-41.
1988: Jack L Arbiser; Cynthia C Morton; G A Bruns; Joseph A Majzoub
Human corticotropin releasing hormone gene is located on the long arm of chromosome 8.
Cytogenetics and cell genetics 1988;47(3):113-6.