FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Hazel Girvan

Research Profile

Chemicals & Drugs

Phenomena

Physiology

Concepts & Ideas

Co-author Network

Publications

TOP 3
Hazel M Girvan; Andrew W Munro
Heme sensor proteins.
Andrew W Munro; Adrian J Dunford; Hazel M Girvan; Amy E Mason; Kirsty J McLean
What makes a P450 tick?
M Gordon Joyce; Andrew W Munro; Rajasekhar Neeli; Olivier Roitel; George J Baker; Robin A Curtis; Adrian J Dunford; Idorenyin S Ekanem; Hazel M Girvan; David Leys
The crystal structure of the FAD/NADPH-binding domain of flavocytochrome P450 BM3.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Hazel Girvan (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Hazel M Girvan; Andrew W Munro
Heme sensor proteins.
The Journal of biological chemistry 2013;288(19):13194-203.
2013: Andrew W Munro; Adrian J Dunford; Hazel M Girvan; Amy E Mason; Kirsty J McLean
What makes a P450 tick?
Trends in biochemical sciences 2013;38(3):140-50.
2012: M Gordon Joyce; Andrew W Munro; Rajasekhar Neeli; Olivier Roitel; George J Baker; Robin A Curtis; Adrian J Dunford; Idorenyin S Ekanem; Hazel M Girvan; David Leys
The crystal structure of the FAD/NADPH-binding domain of flavocytochrome P450 BM3.
The FEBS journal 2012;279(9):1694-706.
2011: Timothy N Waltham; Hazel M Girvan; Christopher F Butler; Stuart R Rigby; Adrian J Dunford; Robert A Holt; Andrew W Munro
Analysis of the oxidation of short chain alkynes by flavocytochrome P450 BM3.
Metallomics : integrated biometal science 2011;3(4):369-78.
2011: Hazel M Girvan; Adrian J Dunford; Rajasekhar Neeli; Idorenyin S Ekanem; Timothy N Waltham; M Gordon Joyce; David Leys; Robin A Curtis; Paul Williams; Karl Fisher; Michael W Voice; Andrew W Munro
Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer.
Archives of biochemistry and biophysics 2011;507(1):75-85.
2010: Hazel M Girvan; Colin W Levy; Paul Williams; Karl Fisher; Myles R Cheesman; Stephen E J Rigby; David Leys; Andrew W Munro
Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
The Biochemical journal 2010;427(3):455-66.
2009: Adrian J Dunford; Hazel M Girvan; Nigel S Scrutton; Andrew W Munro
Probing the molecular determinants of coenzyme selectivity in the P450 BM3 FAD/NADPH domain.
Biochimica et biophysica acta 2009;1794(8):1181-9.
2009: Hazel M Girvan; Helen S Toogood; Rachael E Littleford; Harriet E Seward; W Ewen Smith; Idorenyin S Ekanem; David Leys; Myles R Cheesman; Andrew W Munro
Novel haem co-ordination variants of flavocytochrome P450BM3.
The Biochemical journal 2009;417(1):65-76.
2007: Kirsty J McLean; Hazel M Girvan; Andrew W Munro
Cytochrome P450/redox partner fusion enzymes: biotechnological and toxicological prospects.
Expert opinion on drug metabolism & toxicology 2007;3(6):847-63.
2007: Sibylle Brenner; sam hay; Hazel M Girvan; Andrew W Munro; Nigel S Scrutton
Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed "proximal-distal" transition probed by temperature-jump spectroscopy.
The journal of physical chemistry. B 2007;111(27):7879-86.
2007: Andrew W Munro; Hazel M Girvan; Kirsty J McLean
Variations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily.
Natural product reports 2007;24(3):585-609.
2007: Hazel M Girvan; Derren J Heyes; Nigel S Scrutton; Andrew W Munro
Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale.
Journal of the American Chemical Society 2007;129(20):6647-53.
2007: Andrew W Munro; Hazel M Girvan; Kirsty J McLean
Cytochrome P450--redox partner fusion enzymes.
Biochimica et biophysica acta 2007;1770(3):345-59.
2007: Hazel M Girvan; Harriet E Seward; Helen S Toogood; Myles R Cheesman; David Leys; Andrew W Munro
Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.
The Journal of biological chemistry 2007;282(1):564-72.
2007: Michael A Noble; Hazel M Girvan; Susan J Smith; W Ewen Smith; Marat B Murataliev; Victor M Guzov; René Feyereisen; Andrew W Munro
Analysis of the interactions of cytochrome b5 with flavocytochrome P450 BM3 and its domains.
Drug metabolism reviews 2007;39(2-3):599-617.
2006: Kirsty J McLean; Adrian J Dunford; Muna Sabri; Rajasekhar Neeli; Hazel M Girvan; Philip R Balding; David Leys; Harriet E Seward; Ker R Marshall; Andrew W Munro
CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen.
Biochemical Society transactions 2006;34(Pt 6):1178-82.
2006: Hazel M Girvan; T N Waltham; Rajasekhar Neeli; H F Collins; Kirsty J McLean; Nigel S Scrutton; David Leys; Andrew W Munro
Flavocytochrome P450 BM3 and the origin of CYP102 fusion species.
Biochemical Society transactions 2006;34(Pt 6):1173-7.
2006: Kirsty J McLean; Ashley J Warman; Harriet E Seward; Ker R Marshall; Hazel M Girvan; Myles R Cheesman; Michael R Waterman; Andrew W Munro
Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions.
Biochemistry 2006;45(27):8427-43.
2005: Harriet E Seward; Hazel M Girvan; Andrew W Munro
Cytochrome P450s: creating novel ligand sets.
Dalton transactions (Cambridge, England : 2003) 2005;(21):3419-26.
2005: Rajasekhar Neeli; Hazel M Girvan; Andrew Lawrence; Martin J Warren; David Leys; Nigel S Scrutton; Andrew W Munro
The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase.
FEBS letters 2005;579(25):5582-8.
2005: Ashley J Warman; Olivier Roitel; Rajasekhar Neeli; Hazel M Girvan; Harriet E Seward; S A Murray; Kirsty J McLean; M Gordon Joyce; Helen S Toogood; R A Holt; David Leys; Nigel S Scrutton; Andrew W Munro
Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme.
Biochemical Society transactions 2005;33(Pt 4):747-53.
2004: Luca Quaroni; Harriet E Seward; Kirsty J McLean; Hazel M Girvan; Tobias W B Ost; Michael A Noble; Sharon M Kelly; Nicholas C Price; Myles R Cheesman; W Ewen Smith; Andrew W Munro
Interaction of nitric oxide with cytochrome P450 BM3.
Biochemistry 2004;43(51):16416-31.
2004: Hazel M Girvan; Ker R Marshall; Rachel J Lawson; David Leys; M Gordon Joyce; John Clarkson; W Ewen Smith; Myles R Cheesman; Andrew W Munro
Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set.
The Journal of biological chemistry 2004;279(22):23274-86.
2004: M Gordon Joyce; Hazel M Girvan; Andrew W Munro; David Leys
A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.
The Journal of biological chemistry 2004;279(22):23287-93.
2003: Stéphane Marchal; Hazel M Girvan; Antonius C F Gorren; Bernd Mayer; Andrew W Munro; Claude Balny; Reinhard Lange
Formation of transient oxygen complexes of cytochrome p450 BM3 and nitric oxide synthase under high pressure.
Biophysical journal 2003;85(5):3303-9.